Temperature-controlled cell ultra-clean workbench

By introducing a temperature control system into the clean bench, the problem of temperature changes affecting the accuracy of experimental data was solved, and real-time temperature control and constant temperature were achieved, improving the controllability and asepticity of the experiment.

CN224573784UActive Publication Date: 2026-07-31SHENZHEN AOLI BIOTECHNOLOGY CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
SHENZHEN AOLI BIOTECHNOLOGY CO LTD
Filing Date
2025-07-29
Publication Date
2026-07-31

AI Technical Summary

Technical Problem

Existing cell clean benches suffer from temperature variations that affect the accuracy of experimental data during long-term cell experiments. Furthermore, the use of low-temperature storage for reagents and antibodies increases the risk of contamination and wastes space.

Method used

A temperature control system is installed in the clean bench, including a temperature probe, control module, delivery pipeline, cooling module and heating module, to realize real-time detection and regulation of the operating table temperature and ensure constant temperature.

Benefits of technology

It improves the controllability of experiments, reduces the waste of operating space, lowers the risk of contamination, and enhances the sterility of the experimental environment.

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Abstract

This invention belongs to the field of cell culture technology, and specifically relates to a temperature-controlled cell clean bench. The invention provides a temperature-controlled cell clean bench, comprising a clean bench body, a temperature control system, and a purification system. The temperature control system can detect and regulate the temperature of the clean bench in real time, further enhancing the controllability of cell experiments conducted by researchers in the clean bench and effectively saving operating space.
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Description

Technical Field

[0001] This utility model relates to the field of cell culture technology, and in particular to a temperature-controlled cell clean bench. Background Technology

[0002] Existing cleanroom cell workstations lack temperature control systems, which can further affect the accuracy of cell experimental data during prolonged cell experiments due to temperature fluctuations. For reagents and antibodies requiring cryopreservation, they typically need to be transported to the cleanroom in styrofoam boxes with ice packs, increasing the risk of contamination and wasting space within the cleanroom. Therefore, intelligent temperature control for cleanroom cell workstations is essential. Utility Model Content

[0003] To address the aforementioned issues, this invention provides a temperature-controlled cell clean bench. The clean bench is equipped with a temperature control system that monitors and regulates the temperature of the clean bench in real time, further enhancing the controllability of cell experiments conducted by researchers in the clean bench and effectively saving operating space.

[0004] This utility model embodiment proposes a temperature-controlled cell ultra-clean workbench, comprising:

[0005] The clean bench body includes a top, an operating area, a support column, and a bottom.

[0006] A temperature control system, comprising a temperature probe, a control module, a delivery pipeline, a temperature control board, a refrigeration module, and a heating module;

[0007] A purification system is installed inside the top of the main body, and the purification system includes an air outlet, a fan, and a filter.

[0008] The operating area includes an operating table, and a temperature control plate for regulating the temperature of the operating table is located below the operating table. The temperature control plate is connected to the refrigeration module and the heating module through the delivery pipe.

[0009] The temperature probe in the temperature control system can detect the temperature of the operating table in real time and transmit the temperature information to the control module through an electrical signal. The control module compares the detected temperature with the user-preset temperature threshold. If the detected temperature is less than or greater than the temperature threshold, the control module will instruct the cooling module or heating module to work, thereby adjusting the temperature of the temperature control board to achieve a constant operating table temperature.

[0010] In one possible implementation, the refrigeration module is used to prepare cold air, and the heating module is used to prepare hot air.

[0011] In one possible implementation, the refrigeration module is used to prepare a cold liquid, and the heating module is used to prepare a hot liquid.

[0012] In one possible implementation, the purification system further includes an ultraviolet sterilization lamp for sterilization, maintaining the laminar flow hood in a sterile environment.

[0013] In one possible implementation, a dust filter is installed at the air vent to prevent excessive dust from entering the vent and extend the service life of the filter.

[0014] In one possible implementation, the temperature probe is connected to the operating console and electrically connected to the control module.

[0015] In one possible implementation, the temperature control system also includes an alarm that will sound when the temperature probe detects a temperature higher or lower than a preset value, reminding the experimenter to take appropriate action in a timely manner.

[0016] In one possible implementation, the temperature control system further includes a temperature display device to provide real-time feedback to the user on the temperature detected by the temperature probe.

[0017] In one possible implementation, the operating table is also equipped with a manual adjustment device, which is electrically connected to the control module. When the temperature control system malfunctions and cannot automatically and accurately regulate the temperature, the experimenter can manually adjust the temperature of the operating table through the manual adjustment device. Attached Figure Description

[0018] To more clearly illustrate the technical solutions of the embodiments of this application, the drawings used in the description of the embodiments of this application will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0019] Figure 1 This is a three-dimensional schematic diagram of the temperature-controlled cell ultra-clean workbench provided in this embodiment of the utility model;

[0020] Figure 2 This is a three-dimensional schematic diagram of the temperature control board provided in this embodiment of the utility model;

[0021] Figure 3 This is a schematic diagram showing the connection relationship between the temperature probe, control module, delivery pipeline, refrigeration module, and heating module provided in this embodiment of the utility model.

[0022] Figure label:

[0023] 1- The body of the ultra-clean workbench;

[0024] 11-Top of the main body, 12-Operating area, 13-Support column, 14-Bottom of the main body;

[0025] 2-Temperature control system;

[0026] 201-Temperature probe, 202-Control module, 204-Delivery pipe, 203-Refrigeration module, 205-Heating module;

[0027] 16-Control panel, 161-Temperature control board, 1612-Conduction channel. Detailed Implementation

[0028] The embodiments of this implementation are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this implementation, and should not be construed as limiting this implementation.

[0029] In the description of this embodiment, it should be understood that the orientation descriptions, such as up, down, front, back, left, right, etc., are based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this embodiment and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this embodiment.

[0030] In the description of this embodiment, "several" means one or more, "multiple" means two or more, "greater than," "less than," and "exceeding" are understood to exclude the stated number, while "above," "below," and "within" are understood to include the stated number. The use of "first" and "second" in the description is merely for distinguishing technical features and should not be construed as indicating or implying relative importance, or implicitly indicating the number of indicated technical features, or implicitly indicating the order of the indicated technical features.

[0031] In the description of this embodiment, unless otherwise explicitly limited, terms such as setting, installing, and connecting should be interpreted broadly, and those skilled in the art can reasonably determine the specific meaning of the above terms in this embodiment in conjunction with the specific content of the technical solution.

[0032] The following combination Figure 1-3 This invention provides a detailed description of the clean bench provided in the embodiments of the present invention.

[0033] Figure 1 This is a three-dimensional schematic diagram of the clean bench provided in this embodiment of the present invention. Figure 2 yes Figure 1 A 3D schematic diagram of the temperature control panel below the operating table 16 in the clean bench. Figure 3This is a schematic diagram showing the connection relationship between the temperature probe, control module, delivery pipeline, refrigeration module, and heating module provided in this embodiment of the utility model.

[0034] refer to Figure 1 The clean bench provided in this embodiment includes a clean bench body 1, with a top 11 at the top of the body. The top 11 can be a cube, cuboid, or any other geometric shape. A purification system for purifying the air inside the operating area is installed inside the top 11. In one possible implementation, the purification system has an air vent communicating with the operating area. The air vent serves as a window for air exchange between the operating area and the filter. In another possible implementation, the air vent is also equipped with a dust filter to filter dust or other impurities in the operating area, preventing them from entering the filter and causing blockage, thus reducing the lifespan of the clean bench. In yet another possible implementation, the purification system also includes an ultraviolet sterilization lamp, which can effectively kill bacteria in the operating area and maintain a sterile environment.

[0035] Continue to refer to Figure 1 In one possible implementation, the operating area 12 is located below the top 11 of the main body and has a semi-enclosed structure. Further, one side of the operating area 12 is connected to the outside for convenient operation by the experimenter. Preferably, the side of the operating area 12 connected to the outside is provided with a removable shielding barrier. This shielding barrier can be transparent glass or plastic to prevent external dust from entering the operating area 12. In one possible implementation, an operating table 16 is installed on the bottom surface of the operating area 12 for placing cell culture dishes or performing cell experiments. The operating table 16 can be the entire bottom surface of the operating area 12 or a portion thereof. In one possible implementation, a temperature control plate 161 is provided below the operating table 16. This temperature control plate 161 can be in direct contact with the operating table 16 or can conduct heat with the operating table 16 through a medium. The specific working principle of the temperature control plate 161 will be explained below with reference to the accompanying drawings.

[0036] Continue to refer to Figure 1 In one possible implementation, a plurality of support columns 13 are provided below the operating area 12. It is understood that the number of these support columns 13 can be [number missing]. Figure 1 The four supports can also be three, five or more. In one possible implementation, the lower part of the support column 13 is connected to the bottom 14 of the main body. It is understood that the lower part of the support column 13 may not have the bottom 14 of the main body and may directly contact the bottom surface. In one possible implementation, detachable pulleys can be provided under the support column 13 to facilitate the overall movement of the clean bench.

[0037] refer to Figure 2 In one possible implementation, the main body of the temperature control plate 161 is made of a thermally conductive metal with high-temperature resistance. It is understood that the main body of the temperature control plate 161 can be one or more metals such as copper, aluminum, and tungsten. In another possible implementation, a conduction channel 1612 is provided inside the temperature control plate 161. Furthermore, the conduction channel 1612 is connected to the delivery pipe 204, and the liquid or gas discharged from the delivery pipe 204 is conducted in the channel. It is understood that the conduction channel 1612 is distributed throughout the entire temperature control plate 161, so that the liquid or gas discharged from the delivery pipe 204 circulates in the conduction channel 1612, thereby changing the overall temperature of the temperature control plate 161.

[0038] refer to Figure 3 In one possible implementation, the temperature control system 2 includes a temperature probe 201 connected to the operating table 16, a control module 202, a delivery pipe 204, a cooling module 203, and a heating module 205. The temperature probe 201 is also connected to a temperature display device, enabling real-time display of the temperature of the operating table 16 detected by the probe 201 to the experimenter. In one possible implementation, the temperature probe 201 is electrically connected to the control module 202, transmitting the detected temperature to the control module 202 via an electrical signal. In another possible implementation, the delivery pipe 204 is connected to both the cooling module 203 and the heating module 205. It is understood that the delivery pipe 204 can selectively open the gate of either the cooling module 203 or the heating module, allowing the gas or liquid prepared by the corresponding module to enter the delivery pipe 204. In one possible implementation, the temperature probe 201 detects the temperature of the operating table 16 and feeds it back to the control module 202. The control module 202 compares the detected temperature with a user-preset temperature threshold. When the temperature threshold is greater than or less than the preset temperature threshold, the control module 202 can send a command to the delivery pipe 204, ordering the delivery pipe 204 to open the gate of the cooling module 203 or the heating module 205, so that the gas or liquid of the corresponding module enters the delivery pipe 204 and enters the conduction channel 1612, thereby adjusting the temperature of the temperature control plate 161 accordingly and achieving the effect of constant temperature of the operating table 16.

[0039] In one possible implementation, the temperature control system 2 also includes an alarm that sounds when the temperature probe 201 detects a temperature higher or lower than a preset value, reminding the experimenter to take appropriate action. In another possible implementation, the operating table 16 is also equipped with a manual adjustment device electrically connected to the control module 202. When the temperature control system 2 malfunctions and cannot automatically and accurately regulate the temperature, the experimenter can manually adjust the temperature of the operating table 16 using the manual adjustment device.

[0040] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "illustrative embodiment," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of this implementation. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0041] Although embodiments of this implementation have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of this implementation, the scope of which is defined by the claims and their equivalents.

Claims

1. A temperature-controlled cell ultra-clean workbench, characterized in that, include: The clean bench body (1) includes a top (11), an operating area (12), a support column (13), and a bottom (14). Temperature control system (2), the temperature control system (2) includes a temperature probe (201), a control module (202), a delivery pipe (204), a temperature control board (161), a refrigeration module (203) and a heating module (205); A purification system is installed inside the top (11) of the main body, and the purification system includes an air outlet, a fan and a filter; The operation area (12) is provided with an operation table (16), and a temperature control plate (161) for regulating the temperature of the operation table (16) is provided below the operation table (16). The temperature control plate (161) is connected to the refrigeration module (203) and the heating module (205) through the delivery pipe (204).

2. The temperature-controlled cell ultra-cleaning workstation of claim 1, wherein, The refrigeration module (203) is used to prepare cold air, and the heating module (205) is used to prepare hot air.

3. The temperature-controlled cell ultra-cleaning workstation of claim 1, wherein, The refrigeration module (203) is used to prepare cold liquid, and the heating module (205) is used to prepare hot liquid.

4. The temperature-controlled cell ultra-cleaning workstation of claim 1, wherein, The purification system also includes ultraviolet sterilization lamps.

5. The temperature-controlled cell ultra-cleaning bench according to claim 1 or 4, wherein, A dustproof net is installed at the air vent.

6. The temperature-controlled cell ultra-cleaning workstation of claim 1, wherein, The temperature probe (201) is connected to the operating table (16) and electrically connected to the control module (202).

7. The temperature-controlled cell ultra-cleaning workstation of claim 1, wherein, The temperature control system (2) also includes an alarm that will issue an alarm when the temperature probe (201) detects a temperature higher or lower than a preset value.

8. The temperature-controlled cell ultra-cleaning station of claim 7, wherein, The temperature control system (2) also includes a temperature display device to provide real-time feedback to the user on the temperature detected by the temperature probe (201).

9. The thermoregulated cell work station of claim 1, wherein, The control panel (16) is also equipped with a manual adjustment device, which is electrically connected to the control module (202).