A laser drilling device for the production of nifedipine controlled-release tablets

Abstract

This utility model provides a laser drilling device for the production of nifedipine controlled-release tablets, relating to the field of nifedipine production technology. It includes a base, with a drill body mounted on the top surface of the base. A fixed platform is provided on the top surface of the base, and a feeding trough is opened inside the fixed platform. A feeding assembly is installed inside the feeding trough. An electric push rod and a motor work together to drive the vertical lifting and rotation of the feeding tray. Combined with the design of a limiting plate, a long plate, and protrusions and concave blocks, it ensures precise positioning of the feeding tray during movement, avoiding errors caused by manual intervention. Simultaneously, the inclined feeding port and feeding tray facilitate feeding. A guide block and guide groove work together to fix the dispensing tray on the top surface of the feeding tray, facilitating the fixed placement of drugs requiring central drilling, achieving continuous automated feeding and reducing downtime.

Description

Technical Field

[0001] This utility model relates to the field of nifedipine production technology, and in particular to a laser drilling device for the production of nifedipine controlled-release tablets. Background Technology

[0002] Nifedipine is a commonly used dihydropyridine antihypertensive drug, and its production process includes key steps such as raw material synthesis, crystallization and purification, and formulation processing. In the formulation stage, the drug carrier or sustained-release matrix needs to be precisely processed (e.g., perforated) to control the drug release rate and meet the requirements of different dosage forms (e.g., sustained-release tablets, controlled-release tablets). Laser perforation technology, due to its advantages such as non-contact operation, high precision, and small heat-affected zone, is applied to the microporous processing of drug carriers to ensure the uniformity and stability of drug release, meeting the stringent requirements of Good Manufacturing Practices (GMP) for formulation processes.

[0003] Chinese Patent Publication No. CN210209099U discloses an adjustable laser punch for punching holes in tablets, including a laser punch and an adjustment assembly disposed at the bottom of the laser punch. The adjustment assembly includes a base, a support, a lifting platform, a guide rod, an adjustment handle, and an adjustment screw. The support is fixed on the base, the guide rod is disposed inside the support, the lifting platform is disposed outside the support, one end of the lifting platform has a slider, the slider is sleeved on the guide rod and can move up and down along the guide rod, the adjustment screw is disposed inside the support, the bottom end of the adjustment screw is movably connected to the base, and the top end is fixedly connected to the adjustment handle, a movable block is fixed on one side of the lifting platform, the movable block is sleeved on the adjustment screw and threadedly connected to the adjustment screw;

[0004] In this existing design, although the position of the laser drill can be fine-tuned by setting an adjustment component at the bottom of the laser drill without disassembling the entire laser drill, thus avoiding assembly errors during installation that could lead to deviations in the drilling position and ensuring drilling accuracy and improving production efficiency, the adjustment component, while enabling fine-tuning of the laser drill, relies on manual operation of the adjustment handle and screw. The adjustment process is cumbersome and prone to human error. For example, the lifting platform moves along the guide rod via a slider, requiring repeated turning of the adjustment screw to complete the positioning. This is not only inefficient but may also lead to a decrease in accuracy due to mechanical wear after multiple adjustments.

[0005] To address this issue, a laser drilling device for the production of nifedipine controlled-release tablets was designed. Utility Model Content

[0006] To address the problems mentioned in the background section, this invention provides a laser drilling device for the production of nifedipine controlled-release tablets, which features precise positioning and reduces errors caused by human intervention.

[0007] This utility model adopts the following technical solution: a laser drilling device for the production of nifedipine controlled-release tablets, including a base, a drilling body installed on the top surface of the base, a fixed platform provided on the top surface of the base, a feeding trough opened inside the fixed platform, a feeding assembly provided inside the feeding trough, the feeding assembly including an electric push rod, a motor and a feeding tray, an electric push rod installed at the center inside the feeding trough, a connecting plate connected to the output end of the electric push rod, a motor installed on the top surface of the connecting plate, the output end of the motor connected to the bottom surface of the feeding tray, a limiting plate installed inside the feeding trough, a protrusion installed at the top of the limiting plate, a long plate installed on the bottom surface of the feeding tray, a concave block installed at the bottom end of the long plate, and a feeding port opened on the inner wall of the feeding trough.

[0008] In a preferred embodiment of the laser drilling equipment for producing nifedipine controlled-release tablets according to this utility model, the fixed platform is a circular platform, and the height of the top surface of the fixed platform is lower than the height of the bottom surface of the drilling device body.

[0009] In a preferred embodiment of the laser drilling equipment for producing nifedipine controlled-release tablets according to this utility model, the long plate is slidably connected in the gap between the limiting plate and the feeding trough.

[0010] In a preferred embodiment of the laser drilling equipment for producing nifedipine controlled-release tablets according to this utility model, the shapes and sizes of the protrusions and concave blocks are matched.

[0011] In a preferred embodiment of the laser drilling equipment for producing nifedipine controlled-release tablets according to this utility model, the feed port is inclined and used to connect to the feed pipe.

[0012] As a preferred embodiment of the laser drilling equipment for producing nifedipine controlled-release tablets according to this utility model, a guide block is installed on the top surface of the feeding tray, a distribution tray is provided on the surface of the feeding tray, a guide groove is opened on the bottom surface of the distribution tray, and a pull block is installed on the top surface of the distribution tray.

[0013] In a preferred embodiment of the laser drilling equipment for producing nifedipine controlled-release tablets according to this utility model, the shape and size of the guide block and the guide groove are matched.

[0014] As a preferred embodiment of the laser drilling equipment for producing nifedipine controlled-release tablets according to this utility model, the top surface of the dispensing tray is provided with a plurality of dispensing grooves, and the plurality of dispensing grooves are distributed in a circumferential array on the surface of the dispensing tray.

[0015] In a preferred embodiment of the laser drilling equipment for producing nifedipine controlled-release tablets according to this utility model, the center of the bottom end of the drilling body is opposite to the center of the material distribution trough.

[0016] Compared with the prior art, the advantages and positive effects of this utility model are as follows: it adopts an electric push rod and a motor to drive the vertical lifting and rotation of the feeding tray. Combined with the design of the limiting plate, the long plate and the convex and concave blocks, it ensures the precise positioning of the feeding tray during movement and avoids errors caused by manual intervention. At the same time, the inclined feeding port and the feeding tray facilitate feeding. Furthermore, a distribution tray is set up. Through the cooperation of the guide block and the guide groove, the distribution tray is fixed on the top surface of the feeding tray, which facilitates the fixed placement of drugs that require center drilling, realizes continuous automated feeding, reduces downtime, and the circumferential array distribution of the distribution groove is aligned with the center of the punch body to further ensure the consistency of the drilling position of each drug carrier, thereby improving the controllability of the drug release rate. Attached Figure Description

[0017] Figure 1 This utility model provides a schematic diagram of a laser drilling device for the production of nifedipine controlled-release tablets. Figure 1 ;

[0018] Figure 2 A partial cross-sectional view of a laser drilling device for the production of nifedipine controlled-release tablets is provided for this utility model.

[0019] Figure 3 This invention proposes a laser drilling device for the production of nifedipine controlled-release tablets. Figure 2 Enlarged view of point A in the middle;

[0020] Figure 4 This utility model provides a schematic diagram of a laser drilling device for the production of nifedipine controlled-release tablets. Figure 2 ;

[0021] Figure 5 This invention presents a partial schematic diagram of a laser drilling device for the production of nifedipine controlled-release tablets.

[0022] Legend:

[0023] 1. Base; 2. Drill body; 3. Fixing platform; 4. Feeding trough; 5. Feeding assembly; 501. Electric push rod; 502. Motor; 503. Feeding tray; 504. Connecting plate; 505. Limiting plate; 506. Protrusion; 507. Long plate; 508. Concave block; 509. Feeding port; 6. Guide block; 7. Distributing tray; 8. Guide groove; 9. Pull block; 10. Distributing trough. Detailed Implementation

[0024] To better understand the above-mentioned objectives, features, and advantages of this utility model, the present utility model will be further described below with reference to the accompanying drawings and embodiments. It should be noted that, unless otherwise specified, the embodiments and features described in these embodiments can be combined with each other.

[0025] Many specific details are set forth in the following description in order to provide a full understanding of the present invention. However, the present invention may also be implemented in other ways different from those described herein. Therefore, the present invention is not limited to the specific embodiments disclosed in the following specification.

[0026] Example 1

[0027] In the prior art, the existing adjustable laser punch for tablet punching includes a laser punch and an adjustment assembly located at the bottom of the laser punch. The adjustment assembly includes a base, a support, a lifting platform, a guide rod, an adjustment handle, and an adjustment screw. The support is fixed on the base, the guide rod is located inside the support, and the lifting platform is located outside the support. One end of the lifting platform has a slider, which is sleeved on the guide rod and can move up and down along the guide rod. The adjustment screw is located inside the support, with its bottom end movably connected to the base and its top end fixedly connected to the adjustment handle. A movable block is fixed on one side of the lifting platform, which is sleeved on the adjustment screw and threadedly connected to the adjustment screw.

[0028] This application incorporates the aforementioned prior art, such as Figures 1 to 3 As shown, this utility model provides a technical solution: a laser drilling device for the production of nifedipine controlled-release tablets, including a base 1, a drilling body 2 installed on the top surface of the base 1, a fixed platform 3 provided on the top surface of the base 1, a feeding trough 4 opened inside the fixed platform 3, a feeding assembly 5 provided inside the feeding trough 4, the feeding assembly 5 including an electric push rod 501, a motor 502 and a feeding tray 503, an electric push rod 501 installed at the center inside the feeding trough 4, a connecting plate 504 connected to the output end of the electric push rod 501, a motor 502 installed on the top surface of the connecting plate 504, the output end of the motor 502 connected to the bottom surface of the feeding tray 503, a limiting plate 505 installed inside the feeding trough 4, a protrusion 506 installed at the top of the limiting plate 505, a long plate 507 installed on the bottom surface of the feeding tray 503, a concave block 508 installed at the bottom end of the long plate 507, and a feeding port 509 opened on the inner wall of the feeding trough 4.

[0029] In this implementation plan, a feeding assembly 5 is provided, which is driven by an electric push rod 501 and a motor 502 to realize the vertical lifting and rotation of the feeding tray 503. Combined with the engagement of the protrusion 506 on the surface of the limiting plate 505 and the concave block 508 on the surface of the long plate 507, the feeding tray 503 can be accurately positioned during movement, avoiding errors caused by manual intervention and improving the accuracy of laser drilling.

[0030] Combining the above solutions:

[0031] Furthermore:

[0032] like Figure 1 As shown;

[0033] To facilitate material loading, in an optional embodiment, the fixed platform 3 is a circular platform, and the height of the top surface of the fixed platform 3 is lower than the height of the bottom surface of the punch body 2.

[0034] In this embodiment: the fixed platform 3 is set as a circular platform, and the height of the top surface of the fixed platform 3 is lower than the height of the bottom surface of the punch body 2, so that the punch body 2 can punch the material and facilitate feeding, so that the feeding tray 503 can rotate in the feeding groove 4 to punch different drugs.

[0035] Combining the above solutions:

[0036] Furthermore:

[0037] like Figures 2 to 4 As shown;

[0038] To facilitate the lifting and lowering of the feeding tray 503, in an optional embodiment, the long plate 507 is slidably connected in the gap between the limiting plate 505 and the feeding trough 4.

[0039] In this embodiment, the long plate 507 is slidably connected in the gap between the limiting plate 505 and the feeding groove 4, so that the electric push rod 501 can drive the feeding plate 503 to rise and fall vertically.

[0040] Combining the above solutions:

[0041] Furthermore:

[0042] like Figures 2 to 3 As shown;

[0043] In an optional embodiment, to limit the lifting height of the feed tray 503, the protrusions 506 and concave blocks 508 are matched in shape and size.

[0044] In this embodiment: the shapes and sizes of the protrusions 506 and the concave blocks 508 are matched. When the long plate 507 moves to the top of the limiting plate 505, the protrusions 506 and the concave blocks 508 are locked together to prevent the long plate 507 from disengaging from the limiting plate 505, thereby limiting the lifting height of the feeding tray 503 and avoiding affecting its operation.

[0045] Combining the above solutions:

[0046] Furthermore:

[0047] like Figure 2 and Figure 4 As shown;

[0048] To facilitate material loading, in an optional embodiment, the loading port 509 is inclined for connecting to the loading pipe.

[0049] In this embodiment: when the long plate 507 is at the top of the limiting plate 505, the punch body 2 can punch holes in the medicine on the top surface of the feeding tray 503. At this time, the long plate 507 completely blocks the feeding port 509. When the long plate 507 is at the bottom of the limiting plate 505, the long plate 507 gradually moves down and the feeding port 509 is exposed. Since the feeding port 509 is connected to the feeding pipe, the material can fall from the inclined feeding port 509 to the top surface of the feeding tray 503.

[0050] Combining the above solutions:

[0051] Furthermore:

[0052] like Figures 4 to 5 As shown;

[0053] To improve drilling efficiency, in an optional embodiment, a guide block 6 is installed on the top surface of the feeding tray 503, a distribution tray 7 is provided on the surface of the feeding tray 503, a guide groove 8 is opened on the bottom surface of the distribution tray 7, and a pull block 9 is installed on the top surface of the distribution tray 7.

[0054] In this embodiment, a distribution plate 7 is provided on the surface of the feeding plate 503, which can perform center punching on multiple groups of materials at one time, thus improving the punching efficiency.

[0055] Combining the above solutions:

[0056] Furthermore:

[0057] like Figures 4 to 5 As shown;

[0058] In an optional embodiment, the guide block 6 and the guide groove 8 are matched in shape and size to secure the dispensing disc 7.

[0059] In this embodiment: an irregularly shaped guide block 6 is installed on the top surface of the feeding tray 503, and a guide groove 8 matching the shape and size of the guide block 6 is opened on the bottom surface of the distributing tray 7. The distributing tray 7 can be fixed on the top surface of the feeding tray 503 by the engagement of the guide block 6 and the guide groove 8, making it convenient to pick up and put down the distributing tray 7.

[0060] Combining the above solutions:

[0061] Furthermore:

[0062] like Figures 4 to 5 As shown;

[0063] To facilitate multiple sets of drilling, in an optional embodiment, the top surface of the material distribution plate 7 is provided with a plurality of material distribution grooves 10, which are distributed in a circular array on the surface of the material distribution plate 7.

[0064] In this embodiment: a plurality of material distribution slots 10 are opened on the top surface of the material distribution plate 7, and the plurality of material distribution slots 10 are arranged in a circular array on the surface of the material distribution plate 7, so that when the motor 502 drives the feeding plate 503 to rotate, it drives the material distribution plate 7 to rotate, thereby driving the material in the material distribution slots 10 to rotate, so that the punch body 2 punches holes in the material.

[0065] Combining the above solutions:

[0066] Furthermore:

[0067] like Figure 1 As shown;

[0068] To facilitate center drilling, in an optional embodiment, the center of the bottom end of the punch body 2 is opposite to the center of the material distribution groove 10.

[0069] In this embodiment: when the material distribution trough 10 moves to the bottom of the punch body 2, since the center of the bottom of the punch body 2 is opposite to the center of the material distribution trough 10, the punch body 2 can punch a hole in the center of the material in the material distribution trough 10.

[0070] Working principle: During use, depending on the required drilling position of the material, select whether to install the distribution plate 7. If the distribution plate 7 needs to be installed, align the guide block 6 and the guide groove 8 so that the distribution plate 7 is engaged with the top surface of the feeding plate 503. Then connect the feeding pipe and the feeding port 509, and start the motor 502 and the electric push rod 501. The motor 502 drives the feeding plate 503 to rotate, while the electric push rod 501 drives the connecting plate 504 to move downward. The connecting plate 504 drives the motor 502 to move. At this time, the feeding plate 503 drives the long plate 507 between the limiting plate 505 and the feeding groove 4. The material slides in the gap until the feeding plate 503 is lower than the feeding port 509. At this time, the material in the feeding port 509 can fall into the distribution trough 10. Then, the electric push rod 501 drives the connecting plate 504 to rise. The connecting plate 504 drives the motor 502 to move. The motor 502 drives the feeding plate 503 to rise until the long plate 507 moves to the top of the limiting plate 505. At this time, the concave block 508 and the convex block 506 are locked together. Under the drive of the motor 502, the feeding plate 503 drives the distribution plate 7 to rotate. The punch body 2 can then perform center punching on the material in the distribution trough 10.

[0071] The above description is merely a preferred embodiment of the present utility model and is not intended to limit the present utility model in any other way. Any person skilled in the art may make changes or modifications to the above-disclosed technical content to create equivalent embodiments for application in other fields. However, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present utility model without departing from the technical solution of the present utility model shall still fall within the protection scope of the technical solution of the present utility model.

Claims

1. A laser drilling apparatus for producing nifedipine controlled release tablets, comprising a base (1), characterized in that: The top surface of the base (1) is equipped with a punch body (2), and the top surface of the base (1) is provided with a fixed platform (3). The fixed platform (3) has a feeding groove (4) inside, and the feeding groove (4) is provided with a feeding assembly (5). The feeding assembly (5) includes an electric push rod (501), a motor (502), and a feeding tray (503). The electric push rod (501) is installed at the center of the feeding groove (4), and the output end of the electric push rod (501) is connected to a connecting plate (503). 4) A motor (502) is installed on the top surface of the connecting plate (504). The output end of the motor (502) is connected to the bottom surface of the feeding tray (503). A limiting plate (505) is installed inside the feeding trough (4). A protrusion (506) is installed on the top of the limiting plate (505). A long plate (507) is installed on the bottom surface of the feeding tray (503). A concave block (508) is installed at the bottom end of the long plate (507). A feeding port (509) is opened on the inner wall of the feeding trough (4).

2. The laser drilling apparatus for manufacturing controlled release nifedipine tablet according to claim 1, wherein: The fixed platform (3) is a circular platform, and the height of the top surface of the fixed platform (3) is lower than the height of the bottom surface of the punch body (2).

3. The laser drilling apparatus for manufacturing nifedipine controlled release tablet according to claim 2, wherein: The long plate (507) is slidably connected in the gap between the limiting plate (505) and the feeding trough (4).

4. The nifedipine controlled release tablet production laser drilling apparatus according to claim 3, characterized in that: The shape and size of the protrusion (506) and the concave block (508) are matched.

5. The laser drilling apparatus for manufacturing controlled release nifedipine tablet according to claim 4, characterized in that: The feed port (509) is inclined and is used to connect to the feed pipe.

6. The laser drilling apparatus for manufacturing nifedipine controlled release tablet according to claim 5, wherein: The top surface of the feeding tray (503) is equipped with a guide block (6), the surface of the feeding tray (503) is provided with a distribution tray (7), the bottom surface of the distribution tray (7) is provided with a guide groove (8), and the top surface of the distribution tray (7) is equipped with a pull block (9).

7. The nifedipine controlled release tablet production laser drilling apparatus according to claim 6, characterized in that: The guide block (6) and the guide groove (8) are matched in shape and size.

8. The nifedipine controlled release tablet production laser drilling apparatus according to claim 7, characterized in that: The top surface of the material distribution plate (7) is provided with a plurality of material distribution grooves (10), and the plurality of material distribution grooves (10) are arranged in a circular array on the surface of the material distribution plate (7).

9. The laser drilling apparatus for manufacturing nifedipine controlled release tablet according to claim 8, wherein: The center of the bottom end of the punch body (2) is opposite to the center of the material distribution groove (10).

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