Labeling device for SPR reagent kit production

The fully automated SPR reagent labeling device enables efficient and accurate labeling and online quality inspection of reagent kits, solving the problems of low automation and unstable labeling accuracy in existing technologies, and ensuring the stability of production efficiency and product quality.

CN224576981UActive Publication Date: 2026-07-31LIANGZHUN SHANGHAI MEDICAL EQUIP CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
LIANGZHUN SHANGHAI MEDICAL EQUIP CO LTD
Filing Date
2025-09-18
Publication Date
2026-07-31

AI Technical Summary

Technical Problem

Existing SPR kits suffer from low automation in the labeling process, unstable labeling accuracy, and the inability to automatically remove defective products online, resulting in low production efficiency and inconsistent product quality.

Method used

A fully automated labeling device was designed, comprising a main frame, a conveying mechanism, a positioning mechanism, a label supply mechanism, a label adsorption and application mechanism, and a detection and rejection mechanism. Through conveyor belt conveying, positioning and clamping, label peeling and application, online detection, and rejection of defective products, a multi-process collaborative operation is achieved.

Benefits of technology

This significantly improved the production efficiency and accuracy of SPR kit labeling, ensured product quality consistency and production process continuity, reduced labor costs, and prevented defective products from being mixed into qualified batches.

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Abstract

This utility model relates to the field of automation equipment technology and discloses a labeling device for SPR reagent kit production, including a conveying mechanism and a label supply mechanism. It innovatively incorporates a positioning mechanism, a label adsorption and attachment mechanism, and a detection and rejection mechanism. During operation, the positioning mechanism first clamps and fixes the delivered reagent kit to ensure labeling accuracy; the label adsorption and attachment mechanism completes the label adsorption and attachment actions; after labeling, the detection and rejection mechanism performs online detection of the products and automatically rejects defective products. This utility model solves the problems of low labeling accuracy and lack of online quality inspection function in existing technologies, realizing a high-precision, fully automated labeling and quality inspection process with high production efficiency and stable and reliable product quality.
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Description

Technical Field

[0001] This utility model relates to the field of automation equipment technology, and in particular to a labeling device for SPR reagent kit production. Background Technology

[0002] Surface plasmon resonance (SPR) technology, as a highly sensitive, real-time, label-free biomolecular interaction analysis technique, has been widely used in life science research, drug screening, and clinical diagnostics. The large-scale production of its core consumable, the SPR reagent kit, is one of the key aspects of its widespread adoption. Labeling is an essential step in the kit production process. The label carries crucial information such as the batch number, expiration date, and identification code; the accuracy and standardization of its application directly affect product quality, traceability, and user experience.

[0003] Currently, labeling of such reagent kits, especially in small to medium-sized production scales, still largely relies on manual or semi-automated methods. Operators need to manually place the reagent kits in the designated positions and then manually affix labels or activate a simple labeling device to complete the affixing. The drawbacks of this method are obvious. First, production efficiency is low; the speed and continuity of manual operation are limited, making it difficult to meet the needs of large-scale production, and it also consumes a significant amount of labor costs. More importantly, due to the randomness of manual operation and the differences in operator skill, it is difficult to ensure the consistency and accuracy of the affixing position of each label, which can easily lead to problems such as misaligned labels, uneven heights, or wrinkles, affecting the neatness of the product appearance.

[0004] To overcome the aforementioned problems, some automated labeling equipment has emerged on the market. While these devices have achieved automation and improved efficiency to a certain extent, they still have shortcomings in practical applications. For example, many general-purpose labeling devices do not provide stable positioning and clamping of reagent kits during transport. When the labeling head applies pressure, the reagent kit is prone to slight displacement or vibration, which directly leads to a decrease in labeling accuracy and fails to meet the stringent requirements for high-precision labeling in the medical reagent field. Therefore, a labeling device for SPR reagent kit production is proposed to address these issues. Utility Model Content

[0005] To overcome the above deficiencies, this utility model provides a labeling device for SPR reagent kit production, aiming to improve the problems of unstable positioning during the labeling process leading to low labeling accuracy, and the lack of online quality detection and automatic rejection functions in the existing SPR reagent kit labeling devices, which result in discontinuous production processes and the risk of defective products being mixed in.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: A labeling device for SPR reagent kit production, comprising: Main frame labeling device; A delivery mechanism, mounted on the main frame labeling device, is used to deliver SPR reagent kits; and A label supply mechanism labeling device, mounted on the main frame labeling device, is used to supply labels; characterized in that the labeling device further includes: A positioning mechanism labeling device is disposed beside the conveying path of the conveying mechanism. The positioning mechanism labeling device includes a positioning plate labeling device, which is used to clamp and fix the reagent kit conveyed to the labeling position. A label adsorption and attachment mechanism is disposed above the positioning mechanism labeling device. The label adsorption and attachment mechanism includes an adsorption plate labeling device capable of vertical lifting and lowering. The adsorption plate labeling device is used to pick up labels from the label supply mechanism labeling device and press down to attach the labels to the reagent kit fixed by the positioning mechanism labeling device; and A detection and rejection mechanism labeling device is disposed downstream of the positioning mechanism labeling device along the conveying direction of the conveying mechanism. The detection and rejection mechanism labeling device includes a detector labeling device and a pusher labeling device. The detector labeling device is used to detect the labeled reagent kits, and the pusher labeling device is used to reject the reagent kits that are detected as unqualified by the detector labeling device from the conveying mechanism.

[0007] As a further description of the above technical solution: The label supply mechanism labeling device includes: an unwinding structure for placing the label roll labeling device, a motor labeling device, and a take-up roller labeling device driven by the motor labeling device. After the label tape of the label roll labeling device is wound around the guide roller labeling device, its backing paper is wound up by the take-up roller labeling device, thereby peeling the label off from the backing paper.

[0008] As a further description of the above technical solution: The label supply mechanism labeling device further includes a horizontally movable table labeling device, which is used to carry the label peeled off from the backing paper; the labeling device also includes a first cylinder assembly for driving the horizontal movement of the movable table labeling device, the first cylinder assembly including a cylinder-labeling device and a guide rod-labeling device, the cylinder-labeling device driving the movable table labeling device to move below and out from below the suction plate labeling device.

[0009] As a further description of the above technical solution: The label adsorption and application mechanism further includes a lower pressure plate labeling device and a second cylinder assembly for driving the lower pressure plate labeling device to move vertically up and down. The adsorption plate labeling device is installed at the bottom of the lower pressure plate labeling device. The second cylinder assembly includes a cylinder labeling device and a guide rod labeling device. The cylinder labeling device is used to drive the lower pressure plate labeling device and the adsorption plate labeling device to perform the lifting and lowering motion of picking up and applying labels.

[0010] As a further description of the above technical solution: The bottom surface of the adsorption plate labeling device is provided with at least one adsorption hole labeling device; the label adsorption and attachment mechanism labeling device also includes a vacuum pump labeling device, which is connected to the adsorption plate labeling device through a vacuum pipe labeling device, and is used to provide negative pressure to the adsorption hole labeling device to adsorb the label.

[0011] As a further description of the above technical solution: The positioning mechanism labeling device further includes a fourth cylinder assembly that drives the positioning plate labeling device. The fourth cylinder assembly includes a cylinder-four labeling device and a guide rod-four labeling device. The cylinder-four labeling device pushes the positioning plate labeling device to fix the reagent kit via the guide rod-four labeling device.

[0012] As a further description of the above technical solution: The labeling device of the detection and rejection mechanism also includes a third cylinder assembly for driving the push plate labeling device. The third cylinder assembly includes a cylinder three-labeling device and a guide rod three-labeling device. The cylinder three-labeling device is used to drive the push plate labeling device to reject the unqualified reagent kit after receiving the unqualified signal from the detector labeling device.

[0013] As a further description of the above technical solution: The conveying mechanism is a conveyor belt labeling device; the main frame labeling device is also equipped with a human-machine interface labeling device, and the bottom of the main frame labeling device is equipped with a foot labeling device.

[0014] This utility model has the following beneficial effects: 1. This utility model integrates multiple processes, including reagent kit delivery, precise positioning, automatic label peeling and delivery, label adsorption, label pressing, post-label online detection, and automatic rejection of defective products, into a fully automated process. Through the coordinated automated operation of the conveyor belt, positioning mechanism, label supply mechanism, label adsorption and application mechanism, and detection and rejection mechanism, no manual intervention is required throughout the entire process, significantly reducing labor costs and greatly improving the overall production efficiency of SPR reagent kit labeling.

[0015] 2. In this invention, a specialized positioning mechanism is used at the labeling station where a four-cylinder-driven positioning plate actively clamps and fixes the reagent kits on the conveyor belt. This structure effectively prevents the reagent kits from shifting or shaking during the labeling process, ensuring that the labeling position of each reagent kit is consistent, thereby significantly improving labeling accuracy and stability.

[0016] 3. In this utility model, an innovative detection and rejection mechanism is set up downstream of the labeling station. Each labeled reagent kit is inspected online by a detector, which can detect defective products such as misaligned or missing labels in real time, and immediately reject them automatically via a three-pronged pneumatic pusher. This achieves online quality monitoring and automatic sorting, effectively preventing defective products from being mixed into qualified batches or flowing into subsequent processes, ensuring both the quality of the final product and the continuity of the production process. Attached Figure Description

[0017] Figure 1 This is a three-dimensional schematic diagram of the labeling device for SPR reagent kit production proposed in this utility model. Figure 2 This is a schematic diagram of the frame structure of the labeling device for SPR reagent kit production proposed in this utility model; Figure 3 This is a schematic diagram of the label adsorption and attachment mechanism of the labeling device for SPR reagent kit production proposed in this utility model. Figure 4 This is a schematic diagram of the label supply mechanism of the labeling device for SPR reagent kit production proposed in this utility model; Figure 5 This is a schematic diagram of the detection and rejection mechanism of the labeling device for SPR reagent kit production proposed in this utility model. Figure 6 This is a schematic diagram of the positioning mechanism of the labeling device for SPR reagent kit production proposed in this utility model.

[0018] Legend: 1. Frame; 2. Label supply mechanism; 201. Motor; 202. Label roll; 203. Rewinding roller; 204. Guide roller; 205. Cylinder 1; 206. Guide rod 1; 207. Moving table; 3. Label adsorption and attachment mechanism; 301. Cylinder 2; 302. Guide rod 2; 303. Lower pressure plate; 304. Adsorption plate; 305. Adsorption hole; 306. Air pump; 307. Air extraction pipe; 4. Conveyor belt; 5. Detection and rejection mechanism; 501. Detector; 502. Cylinder 3; 503. Guide rod 3; 504. Push plate; 6. Positioning mechanism; 601. Cylinder 4; 602. Guide rod 4; 603. Positioning plate; 7. Human-machine interface; 8. Foot. Detailed Implementation

[0019] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0020] Please refer to the appendix. Figure 1 - Appendix Figure 6 This utility model provides a labeling device for SPR reagent kit production, which aims to solve the problems of low automation, unstable labeling accuracy, and inability to automatically remove defective products online in the existing SPR reagent kit labeling process.

[0021] The SPR reagent kit labeling device includes a main frame 1 as a basic support platform. Several feet 8 for supporting and adjusting the level of the equipment are fixedly connected to the bottom of the main frame 1 by bolts. A human-machine interface 7 is also fixedly installed on one side of the main frame 1 for operating control and monitoring the status of the equipment.

[0022] A conveying mechanism is horizontally fixed on the main frame 1. Specifically, the conveying mechanism is a conveyor belt 4 driven by a drive motor. The conveyor belt 4 moves cyclically along a preset path to carry the SPR reagent kit and transport it to each subsequent functional station in sequence.

[0023] A label supply mechanism 2 is also fixedly installed on the main frame 1. The label supply mechanism 2 is set on one side of the conveyor belt 4 and is used to continuously supply labels peeled off from the backing paper.

[0024] On the main frame 1, a positioning mechanism 6 is fixedly installed along the conveying path of the conveyor belt 4. The positioning mechanism 6 includes a positioning plate 603 that can reciprocate horizontally. The movement of the positioning plate 603 is driven by a fourth cylinder assembly. The fourth cylinder assembly includes a cylinder 601 fixed on the main frame 1 and a guide rod 602 fixedly connected to the piston rod of the cylinder 601. The end of the guide rod 602 is fixedly connected to the positioning plate 603, so that the positioning plate 603 can clamp and fix or release the reagent kit on the conveyor belt 4 by the extension and retraction of the cylinder 601.

[0025] Above the conveyor belt 4, and directly opposite the aforementioned positioning mechanism 6, a label adsorption and attachment mechanism 3 is fixedly installed via a bracket. This mechanism includes a lower pressure plate 303 capable of vertical lifting and lowering, with an adsorption plate 304 fixedly connected to the bottom surface of the lower pressure plate 303. The vertical lifting and lowering movement of the lower pressure plate 303 is driven by a second cylinder assembly, which includes a second cylinder 301 vertically fixed to the main frame 1 and a second guide rod 302. The piston rod of the second cylinder 301 is fixedly connected to the upper end of the second guide rod 302, and the lower end of the second guide rod 302 is fixedly connected to the lower pressure plate 303. Multiple adsorption holes 305 are formed on the bottom surface of the adsorption plate 304. Each adsorption hole 305 is collected through a flow channel inside the adsorption plate 304 and connected to an air extraction pipe 307. The other end of the air extraction pipe 307 is connected to the air outlet of an air extraction pump 306 fixedly installed on the main frame 1.

[0026] Downstream of the labeling station along the conveyor belt 4, a detection and rejection mechanism 5 is also provided. The detection and rejection mechanism 5 includes a detector 501 fixed on the main frame 1. The detection probe of the detector 501 faces the conveying path of the conveyor belt 4 below. On one side of the conveyor belt 4, corresponding to the position of the detector 501, a third cylinder assembly is fixedly installed. The third cylinder assembly includes a horizontally arranged cylinder 3 502 and a guide rod 3 503. The piston rod of the cylinder 3 502 is fixedly connected to one end of the guide rod 3 503, and the other end of the guide rod 3 503 is fixedly connected to a push plate 504. The initial position of the push plate 504 is located outside the conveyor belt 4, and its pushing stroke is adapted to the width of the conveyor belt 4.

[0027] In a preferred embodiment, the aforementioned label supply mechanism 2 is specifically configured as follows: it includes an unwinding structure for mounting the entire label roll 202, a motor 201 fixedly mounted on the main frame 1, and a winding roller 203 driven by the motor 201 through a transmission mechanism; the label tape led out from the label roll 202 has a guide roller 204 for tensioning and guiding on its travel path, and after the label tape passes around the guide roller 204, its backing paper is wound up by the winding roller 203, and the label and backing paper are separated at the peeling point.

[0028] To achieve accurate label delivery, the label supply mechanism 2 also includes a movable stage 207 that can be reciprocated and slidably connected to the main frame 1 in the horizontal direction. The top surface of the movable stage 207 is used to support the label that has just been peeled off from the backing paper. The movable stage 207 is driven to move horizontally by a first cylinder assembly, which includes a horizontally fixed cylinder 205 and a guide rod 206. The piston rod of the cylinder 205 is fixedly connected to the movable stage 207 via the guide rod 206.

[0029] In the aforementioned label adsorption and attachment mechanism 3, the adsorption plate 304 is fixedly installed on the bottom surface of the lower pressure plate 303 by fasteners. The lower pressure plate 303 is fixedly connected to the lower end of the guide rod 302 of the second cylinder assembly that drives its lifting and lowering. The upper end of the guide rod 302 is fixedly connected to the piston rod of the cylinder 301. The cylinder body of the cylinder 301 is vertically fixedly installed on the main frame 1, thus forming a stable vertical motion unit.

[0030] To achieve reliable label adsorption, the vacuum pump 306 is connected to the vacuum chamber inside the adsorption plate 304 through the vacuum pipe 307. This vacuum chamber is also connected to all the adsorption holes 305 on the bottom surface. When the vacuum pump 306 is working, a negative pressure airflow is formed at the adsorption holes 305.

[0031] In the aforementioned positioning mechanism 6, the cylinder 601 of the fourth cylinder assembly is horizontally fixed on the main frame 1, and its piston rod is fixedly connected to the positioning plate 603 through the guide rod 602. When the piston rod of the cylinder 601 extends, it pushes the positioning plate 603 to push the reagent kit to the fixed baffle on the other side of the conveyor belt 4, thereby achieving a firm clamping.

[0032] In the aforementioned detection and rejection mechanism 5, the cylinder 3 502 of the third cylinder assembly is horizontally fixed on the main frame 1, and its piston rod is fixedly connected to the push plate 504 through the guide rod 3 503. When the detector 501 identifies the defective product and sends a control signal, the cylinder 3 502 is activated, driving the push plate 504 to extend instantly and push the defective reagent kit out of the running track of the conveyor belt 4.

[0033] Working principle: During operation, the SPR reagent kit to be labeled is first placed at the starting end of the conveyor belt 4. Under the action of the drive motor, the conveyor belt 4 smoothly transports the reagent kit to the designated labeling position. When the reagent kit reaches the position, the cylinder 601 of the positioning mechanism 6 is activated. Its piston rod pushes the positioning plate 603 towards the reagent kit through the guide rod 602. The positioning plate 603 pushes the reagent kit towards the fixed baffle on the other side of the conveyor belt 4 and clamps and fixes it, thereby preventing the reagent kit from shifting during the labeling process and effectively improving the labeling accuracy.

[0034] At the same time, the label supply mechanism 2 starts working. The motor 201 starts and drives the right-side take-up roller 203 to rotate. The label strip on the label roll 202 is unwound in an orderly manner from the left side under the guidance of the guide roller 204, and its backing paper is wound up by the right-side take-up roller 203, so that the label is peeled off from the backing paper at the front end of the moving table 207 and waits to be picked up.

[0035] After the label is peeled off, cylinder 205 of the first cylinder assembly is activated, and its piston rod drives the moving stage 207 to slide to the left through the guide rod 206, so that the moving stage 207 carrying the peeled label is precisely moved to directly below the adsorption plate 304.

[0036] Next, the label adsorption and attachment mechanism 3 begins to perform the label picking action. The second cylinder 301 of the second cylinder assembly is activated, and its piston rod drives the lower pressure plate 303 and the adsorption plate 304 installed at the bottom of the lower pressure plate 303 to move vertically downward through the guide rod 302. At the same time, the vacuum pump 306 evacuates the vacuum chamber inside the adsorption plate 304 through the vacuum pipe 307, so that the adsorption hole 305 at the bottom of the adsorption plate 304 generates negative pressure. When the adsorption plate 304 presses down and contacts the peeled label, the label is firmly adsorbed onto the bottom surface of the adsorption plate 304 by the negative pressure. After adsorption is completed, the second cylinder 301 moves in the opposite direction, driving the adsorption plate 304 to lift vertically.

[0037] As the adsorption plate 304 is lifted, cylinder 205 is activated again, causing the moving platform 207 to slide to the right, moving it out from under the adsorption plate 304 to make room for the subsequent labeling action.

[0038] Then, the labeling operation is performed. Cylinder 2 301 is started again, which drives the adsorption plate 304, which has been adsorbed with the label, to press vertically downward onto the SPR reagent kit that has been fixed by the positioning mechanism 6. With appropriate pressure, the label is flat and firmly attached to the reagent kit.

[0039] After labeling is completed, positioning mechanism 6 releases the reagent kit, and conveyor belt 4 restarts, transporting the labeled reagent kit to the detector 501 of detection and rejection mechanism 5. Detector 501 performs real-time detection on the labeled reagent kit to determine if there are any defects such as misaligned labels, missing labels, or damaged labels. When detector 501 detects a defective product, it immediately sends a signal to the third cylinder assembly, which starts cylinder 502. Its piston rod pushes push plate 504 through guide rod 503, pushing the defective reagent kit off conveyor belt 4 for automatic rejection. Reagent kits that pass the detector 501 test will continue to be transported to the right along conveyor belt 4, thus preventing defective products from mixing with qualified batches and ensuring the continuity of the production process and the stability of product quality. The entire process is monitored and controlled by human-machine interface 7, and foot 8 ensures the stable operation of the equipment.

[0040] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A labeling device for SPR reagent kit production, comprising: Main frame (1); A delivery mechanism, which is located on the main frame (1), is used to deliver the SPR reagent kit; as well as A label supply mechanism (2), which is mounted on the main frame (1), is used to supply labels; characterized in that the labeling device further includes: A positioning mechanism (6) is provided beside the conveying path of the conveying mechanism. The positioning mechanism (6) includes a positioning plate (603) for clamping and fixing the reagent kit conveyed to the labeling position. A label adsorption and attachment mechanism (3) is disposed above the positioning mechanism (6). The label adsorption and attachment mechanism (3) includes an adsorption plate (304) capable of vertical lifting and lowering. The adsorption plate (304) is used to pick up a label from the label supply mechanism (2) and press down to attach the label to the reagent kit fixed by the positioning mechanism (6); and The detection and rejection mechanism (5) is located downstream of the positioning mechanism (6) along the conveying direction of the conveying mechanism. The detection and rejection mechanism (5) includes a detector (501) and a pusher plate (504). The detector (501) is used to detect the labeled kits, and the pusher plate (504) is used to reject kits that are detected as unqualified by the detector (501) from the conveying mechanism.

2. The SPR labeler for label production kit according to claim 1, characterized in that: The label supply mechanism (2) includes: an unwinding structure for placing the label roll (202), a motor (201), and a winding roller (203) driven by the motor (201). After the label strip of the label roll (202) passes through the guide roller (204), its backing paper is wound up by the winding roller (203), thereby peeling the label off from the backing paper.

3. The SPR labeler for label production kit according to claim 1, characterized in that: The label supply mechanism (2) further includes a horizontally movable stage (207) for carrying labels peeled off from the backing paper; the labeling device further includes a first cylinder assembly for driving the movable stage (207) to move horizontally, the first cylinder assembly including a cylinder (205) and a guide rod (206), the cylinder (205) driving the movable stage (207) to move below and out of the adsorption plate (304).

4. The labeling device for SPR reagent kit production according to claim 1, characterized in that: The label adsorption and attachment mechanism (3) further includes a lower pressure plate (303) and a second cylinder assembly for driving the lower pressure plate (303) to rise and fall vertically; the adsorption plate (304) is installed at the bottom of the lower pressure plate (303), and the second cylinder assembly includes a second cylinder (301) and a second guide rod (302). The second cylinder (301) is used to drive the lower pressure plate (303) and the adsorption plate (304) to perform the lifting and lowering movements of picking up and attaching labels.

5. The labeling device for SPR reagent kit production according to claim 1, characterized in that: The bottom surface of the adsorption plate (304) is provided with at least one adsorption hole (305); the label adsorption and attachment mechanism (3) further includes an air pump (306), which is connected to the adsorption plate (304) through an air extraction pipe (307) to provide negative pressure to the adsorption hole (305) to adsorb the label.

6. The labeling device for SPR reagent kit production according to claim 1, characterized in that: The positioning mechanism (6) further includes a fourth cylinder assembly that drives the positioning plate (603), the fourth cylinder assembly including cylinder four (601) and guide rod four (602), the cylinder four (601) pushes the positioning plate (603) to fix the reagent kit via the guide rod four (602).

7. The labeling device for SPR reagent kit production according to claim 1, characterized in that: The detection and rejection mechanism (5) further includes a third cylinder assembly for driving the push plate (504). The third cylinder assembly includes a cylinder three (502) and a guide rod three (503). The cylinder three (502) is used to drive the push plate (504) to reject the unqualified reagent kit after receiving the unqualified signal from the detector (501).

8. The labeling device for SPR reagent kit production according to claim 1, characterized in that: The conveying mechanism is a conveyor belt (4); the main frame (1) is also provided with a human-machine interface (7), and the bottom of the main frame (1) is provided with feet (8).