Non-mechanical stirring type ventilation fermentor

Abstract

This utility model relates to a ventilated fermentation tank, specifically a non-mechanically stirred ventilated fermentation tank, comprising a tank body. Inside the tank body is a guide tube for guiding the fermentation broth upwards. Inside the guide tube is a jetting mechanism for supplying oxygen to the fermentation broth. At the bottom of the tank body is a gas-liquid mixing mechanism for supplying air to the jetting mechanism. The gas-liquid mixing mechanism includes a ventilation mechanism for supplying air to the jetting mechanism and a transmission mechanism for driving the ventilation mechanism in an up-and-down piston-like motion. Through the cooperation of the gas-liquid mixing mechanism and the deflection mechanism, the nozzle deflects slightly after each jet to change the jetting direction, achieving three-dimensional dynamic mixing of the fermentation broth. The periodic angle adjustment of the nozzle allows the jetting flow field to cover a wider area, while effectively avoiding uneven oxygen concentration distribution caused by fixed-point jetting, which could lead to oxidative stress in microorganisms.

Description

Technical Field

[0001] This utility model relates to a ventilated fermentation tank, specifically a non-mechanical stirring type ventilated fermentation tank. Background Technology

[0002] Non-mechanically stirred aerated fermenters are widely used in the field of microbial fermentation. Non-mechanically stirred fermenters usually have a simple structure and no complex mechanical parts. Since there is no shearing force generated by mechanical stirrers, the damage to microbial cells is smaller. They are especially suitable for the cultivation of microorganisms that are sensitive to shearing forces, such as filamentous bacteria, animal and plant cells, etc.

[0003] Non-mechanically stirred aerated fermenters play an important role in biochemical production due to their unique advantages. Therefore, non-mechanically stirred fermenters are usually considered when treating microorganisms that are sensitive to shear force.

[0004] Non-mechanically stirred fermenters use methods such as air extraction, liquid extraction, and jetting to treat the fermentation broth. Current fermenters are equipped with multiple nozzles that continuously inject oxygen during the fermentation process, causing the fermentation broth to mix with oxygen. Although multiple nozzles are installed in the fermenter, the jetting airflow will still continuously spray in the opposite direction to the single nozzle. In this case, the area near the nozzle may have a higher oxygen concentration, while the area away from the nozzle may have insufficient oxygen supply. Some microorganisms may produce more oxidative stress in a high-oxygen environment, leading to cell damage, reduced metabolic efficiency, and even inhibited growth. Utility Model Content

[0005] The purpose of this invention is to provide a non-mechanically stirred ventilated fermenter to solve the problem mentioned in the background art where the ejected airflow is still continuously and in a single opposite direction. In this case, the area near the nozzle may have a higher oxygen concentration, while the area away from the nozzle may have insufficient oxygen supply. Some microorganisms may produce more oxidative stress in a high-oxygen environment, leading to cell damage, reduced metabolic efficiency, and even growth inhibition.

[0006] To achieve the above objectives, this utility model provides the following technical solution:

[0007] A non-mechanically stirred ventilated fermenter includes a tank body, a guide tube for guiding the fermentation liquid inside the tank body, a jetting mechanism for supplying oxygen to the fermentation liquid inside the guide tube, and a gas-liquid mixing mechanism for supplying gas to the jetting mechanism at the bottom of the tank body.

[0008] The gas-liquid mixing mechanism includes a ventilation mechanism for supplying gas to the jet mechanism and a transmission mechanism for driving the ventilation mechanism to move up and down in a piston-like motion. A deflection mechanism for adjusting the rotation of the guide tube is provided on one side of the transmission mechanism.

[0009] The non-mechanically stirred ventilated fermenter described above: the jetting mechanism includes three mounting slots opened in the guide tube and air nozzles set on the mounting slots, with the same split air pipe connected to one side of the three air nozzles.

[0010] The non-mechanically stirred ventilated fermenter described above: the ventilation mechanism includes an air cylinder fixed to the bottom of the tank and an air inlet pipe set at the top of the air cylinder, the diversion air pipe is connected to the top of the air cylinder, and a first check valve and a second check valve are respectively installed on the diversion air pipe and the air inlet pipe.

[0011] The non-mechanically stirred ventilated fermenter described above: the transmission mechanism includes a drive motor located at the bottom of the tank and a rotating shaft fixed on the output shaft of the drive motor. A crank is sleeved on the rotating shaft, and a connecting arm is rotatably connected to one end of the crank.

[0012] The non-mechanically stirred ventilated fermenter described above: the transmission mechanism further includes a piston block disposed at the top of the connecting arm, the piston block sliding inside the gas cylinder.

[0013] The non-mechanically stirred ventilated fermenter described above: the deflection mechanism includes a first pulley sleeved on one end of the rotating shaft and a second pulley disposed on the top of the first pulley. The second pulley is provided with a central shaft, and a belt is drivingly connected to the first pulley and the second pulley.

[0014] The non-mechanically stirred ventilated fermenter described above: the deflection mechanism further includes a disc body disposed at the bottom of the guide tube and multiple adjusting plates disposed at the bottom of the disc body. The guide tube is rotatably installed inside the tank body via the disc body, and the adjusting plates cooperate with a toggle plate sleeved on one side of the central shaft.

[0015] Compared with the prior art, the beneficial effects of this utility model are: by cooperating the gas-liquid mixing mechanism and the deflection mechanism, the nozzle deflects slightly after each jet to change the jet direction, thereby realizing the three-dimensional dynamic mixing of the fermentation liquid. The periodic angle adjustment of the nozzle can make the jet flow field cover a wider area, and at the same time, it can effectively avoid the uneven distribution of oxygen concentration caused by fixed-point jet, which can lead to oxidative stress reaction of microorganisms.

[0016] This invention can simultaneously supply oxygen to the nozzle and drive the nozzle to deflect slightly using only one motor device, making it more economical in terms of equipment investment and energy consumption. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the overall structure of a non-mechanically stirred, ventilated fermenter.

[0018] Figure 2 This is a bottom view of the structure of a non-mechanically stirred, ventilated fermenter.

[0019] Figure 3 This is a schematic diagram of the internal structure of a non-mechanically stirred aerated fermenter.

[0020] Figure 4 This is a schematic diagram of the guide tube and gas-liquid mixing mechanism in a non-mechanically stirred ventilated fermenter.

[0021] Figure 5 This is a schematic diagram of the guide tube and gas-liquid mixing mechanism in a non-mechanically stirred ventilated fermenter from another angle.

[0022] Figure 6 This is a bottom view schematic diagram of the guide tube and gas-liquid mixing mechanism in a non-mechanically stirred ventilated fermenter.

[0023] Figure 7 This is a schematic diagram of the internal structure of the guide tube and gas-liquid mixing mechanism in a non-mechanically stirred ventilated fermenter.

[0024] Figure 8 This is a schematic diagram of the internal structure of the gas-liquid mixing mechanism in a non-mechanically stirred ventilated fermenter.

[0025] Figure 9 This is a schematic diagram of the crank, connecting arm, and piston block structure in a non-mechanically stirred ventilated fermenter.

[0026] In the diagram: 1. Tank; 2. Flow guide tube; 3. Disc; 4. Adjusting plate; 5. Air nozzle; 6. Diverter pipe; 7. First check valve; 8. Air cylinder; 9. Inlet pipe; 10. Second check valve; 11. Drive motor; 12. Shaft; 13. Crank; 14. Connecting arm; 15. Piston block; 16. First pulley; 17. Second pulley; 18. Central shaft; 19. Actuating plate. Detailed Implementation

[0027] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.

[0028] Please see Figures 1-9As an embodiment of the present utility model, the non-mechanical stirring type ventilated fermentation tank includes a tank body 1, a guide tube 2 for guiding the fermentation liquid is provided inside the tank body 1, a jet mechanism for supplying oxygen to the fermentation liquid is provided inside the guide tube 2, and a gas-liquid mixing mechanism for supplying gas to the jet mechanism is provided at the bottom of the tank body 1.

[0029] The gas-liquid mixing mechanism includes a ventilation mechanism for supplying gas to the jet mechanism and a transmission mechanism for driving the ventilation mechanism to move up and down in a piston-like motion. A deflection mechanism for adjusting the rotation of the guide tube 2 is provided on one side of the transmission mechanism.

[0030] In this embodiment, in the initial state, the ventilation mechanism is driven by the transmission mechanism to perform up and down piston-like movements, so that the ventilation mechanism introduces external air into the jetting mechanism, and the jetting mechanism introduces oxygen into the tank 1 to perform gas-liquid mixing treatment of the fermentation liquid. At the same time, the transmission mechanism synchronously drives the deflection mechanism to deflect, which drives the guide tube 2 and the jetting mechanism inside the tank 1 to deflect slightly. The oxygen injection and deflection are alternated, so that the jetting mechanism deflects slightly after each injection to change the injection direction, thereby realizing the three-dimensional dynamic mixing of the fermentation liquid.

[0031] As a further embodiment of this utility model, the jetting mechanism includes three mounting slots opened in the guide tube 2 and air nozzles 5 disposed on the mounting slots, with the same split air pipe 6 connected to one side of the three air nozzles 5.

[0032] In this embodiment, three air nozzles 5 are respectively installed in three mounting slots of the guide tube 2, and the split air pipe 6 has three branch pipes that are respectively connected to the three air nozzles 5.

[0033] As a further embodiment of this utility model, the ventilation mechanism includes an air cylinder 8 fixed to the bottom of the tank body 1 and an air inlet pipe 9 disposed on the top of the air cylinder 8. The diversion air pipe 6 is connected to the top of the air cylinder 8, and a first check valve 7 and a second check valve 10 are respectively installed on the diversion air pipe 6 and the air inlet pipe 9.

[0034] In this embodiment, the first check valve 7 prevents the gas in the diversion pipe 6 from flowing back into the gas cylinder 8, and the second check valve 10 prevents the airflow in the gas cylinder 8 from being squeezed to the outside, so that the airflow in the gas cylinder 8 is only squeezed into the diversion pipe 6.

[0035] As a further embodiment of this utility model, the transmission mechanism includes a drive motor 11 disposed at the bottom of the tank body 1 and a rotating shaft 12 fixed on the output shaft of the drive motor 11. A crank 13 is sleeved on the rotating shaft 12, and a connecting arm 14 is rotatably connected to one end of the crank 13.

[0036] In this embodiment, the drive motor 11 and the rotating shaft 12 are located below the air cylinder 8.

[0037] As a further embodiment of this utility model, the transmission mechanism also includes a piston block 15 disposed at the top end of the connecting arm 14, the piston block 15 sliding within the air cylinder 8.

[0038] In this embodiment, the outer wall of the piston block 15 is tightly fitted with the inner wall of the air cylinder 8. The rotation of the rotating shaft 12 drives the crank 13 and the connecting arm 14 to move with the piston block 15, so that the piston block 15 performs up and down piston-like movements inside the air cylinder 8.

[0039] As a further embodiment of this utility model, the deflection mechanism includes a first pulley 16 sleeved on one end of the rotating shaft 12 and a second pulley 17 disposed on the top of the first pulley 16. The second pulley 17 is provided with a central shaft 18, and the first pulley 16 and the second pulley 17 are connected by a belt for transmission.

[0040] In this embodiment, when the shaft 12 rotates, the first pulley 16 drives the second pulley 17 to rotate via a belt, which in turn drives the central shaft 18 to rotate continuously.

[0041] As a further embodiment of this utility model, the deflection mechanism also includes a disc 3 disposed at the bottom of the guide tube 2 and a plurality of adjusting plates 4 disposed at the bottom of the disc 3. The guide tube 2 is rotatably installed inside the tank 1 via the disc 3, and the adjusting plate 4 cooperates with the actuating plate 19 sleeved on one side of the central shaft 18.

[0042] In this embodiment, in the initial state, the piston block 15 is driven by the drive motor 11 to move up and down in the air cylinder 8, so that the external air is continuously compressed into the diversion pipe 6, and then the oxygen is injected into the fermentation liquid by the air nozzle 5. Since the rotating shaft 12 that drives the piston block 15 to move up and down is coaxially engaged with the actuating plate 19, when the piston block 15 descends, the air cylinder 8 is filled with air. At the same time, the force-bearing end of the actuating plate 19 will rotate upward and push the adjusting plate 4 at the bottom of the guide tube 2 to one side, so that the guide tube 2 and the jetting mechanism deflect slightly. This achieves a slight deflection to change the jetting direction after each jetting, while the position of the air nozzle 5 remains unchanged during the jetting process.

[0043] The above embodiments are exemplary and not restrictive. Therefore, without departing from the spirit or basic characteristics of this utility model, any technical solutions that can be implemented in other specific forms are included in this utility model.

Claims

1. A non-mechanically stirred ventilated fermenter, comprising a tank body (1), characterized in that, The tank (1) is provided with a guide tube (2) for guiding the fermentation liquid, and the guide tube (2) is provided with a jetting mechanism for supplying oxygen to the fermentation liquid. The bottom of the tank (1) is provided with a gas-liquid mixing mechanism for supplying gas to the jetting mechanism. The gas-liquid mixing mechanism includes a ventilation mechanism for supplying gas to the jet mechanism and a transmission mechanism for driving the ventilation mechanism to move up and down in a piston-like motion. A deflection mechanism for adjusting the rotation of the guide tube (2) is provided on one side of the transmission mechanism.

2. The non-mechanically stirred ventilated fermenter according to claim 1, characterized in that, The jetting mechanism includes three mounting slots opened in the guide tube (2) and air nozzles (5) set on the mounting slots. One side of the three air nozzles (5) is connected to the same split air pipe (6).

3. A non-mechanically stirred ventilated fermenter according to claim 2, characterized in that, The ventilation mechanism includes an air cylinder (8) fixed at the bottom of the tank (1) and an air inlet pipe (9) set at the top of the air cylinder (8). The diversion pipe (6) is connected to the top of the air cylinder (8). A first check valve (7) and a second check valve (10) are respectively installed on the diversion pipe (6) and the air inlet pipe (9).

4. A non-mechanically stirred ventilated fermenter according to claim 3, characterized in that, The transmission mechanism includes a drive motor (11) located at the bottom of the tank (1) and a rotating shaft (12) fixed on the output shaft of the drive motor (11). A crank (13) is sleeved on the rotating shaft (12), and a connecting arm (14) is rotatably connected to one end of the crank (13).

5. A non-mechanically stirred ventilated fermenter according to claim 4, characterized in that, The transmission mechanism also includes a piston block (15) disposed at the top of the connecting arm (14), the piston block (15) sliding inside the air cylinder (8).

6. A non-mechanically stirred ventilated fermenter according to claim 5, characterized in that, The deflection mechanism includes a first pulley (16) sleeved on one end of the rotating shaft (12) and a second pulley (17) disposed on the top of the first pulley (16). The second pulley (17) is provided with a central shaft (18), and the first pulley (16) and the second pulley (17) are connected by a belt for transmission.

7. A non-mechanically stirred ventilated fermenter according to claim 6, characterized in that, The deflection mechanism also includes a disc (3) at the bottom of the guide tube (2) and a plurality of adjusting plates (4) at the bottom of the disc (3). The guide tube (2) is rotatably installed inside the tank (1) via the disc (3). The adjusting plate (4) cooperates with the actuating plate (19) sleeved on one side of the central shaft (18).

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