Detection consumables and detection apparatus

Abstract

This utility model belongs to the field of medical device technology, specifically relating to a testing consumable and a testing device. The testing consumable includes: a sample tube for containing a first reagent; a reaction tube for containing a second reagent, the sample tube and the reaction tube being detachably connected; a diaphragm located between the reaction tube and the sample tube and used to isolate the two tubes, the diaphragm being detachably connected to both the sample tube and the reaction tube; and a piston assembly housed within the sample tube and including a piston and a piercing head, the piercing head being located at the bottom of the piston and used to pierce the diaphragm. Using the above-mentioned testing consumable can prevent the diaphragm from being corroded by strongly alkaline or corrosive substances in the first reagent, thereby improving testing accuracy and effectiveness.

Description

Technical Field

[0001] This utility model belongs to the field of medical device technology, specifically relating to a testing consumable and a testing device. Background Technology

[0002] In the sample processing (such as sputum, urine, blood), the sample needs to be pretreated by adding a processing solution to a test tube, and the pretreated mixed solution is then transferred to another container using a pipette before subsequent detection processes such as nucleic acid extraction or PCR amplification can be carried out.

[0003] In the prior art, there are some consumable structures that complete the pretreatment, aspiration, and output steps within a single consumable, with separate sample tubes and reaction tubes, separated by a diaphragm. However, existing testing consumables are typically one-piece structures, with the sample tube, diaphragm, and reaction tube inseparable. This means the consumable can only perform sample testing based on the reagents in the reaction tube, resulting in poor testing compatibility and inconvenient transportation. Utility Model Content

[0004] The purpose of this invention is to provide a testing consumable and a testing device to solve the technical problems of poor testing compatibility and inconvenient transportation of integrated testing consumables in the prior art.

[0005] To achieve the above objectives, this utility model provides a testing consumable, which includes:

[0006] Sample tubes, used to contain the first reagent;

[0007] The reaction tube is used to contain the second reagent, and the sample tube is detachably connected to the reaction tube.

[0008] A diaphragm is located between the reaction tube and the sample tube and is used to isolate the reaction tube and the sample tube. The diaphragm can be detachably connected to both the sample tube and the reaction tube.

[0009] A piston assembly, housed within a sample tube, includes a piston and a puncture head located at the bottom of the piston for puncturing the diaphragm.

[0010] In some embodiments, the outer periphery of the reaction tube is snapped into the inner peripheral wall of the sample tube. The diaphragm includes a sleeve portion, a diaphragm portion, and a guide portion connected in sequence. The sleeve portion is sleeved on the outer periphery of the reaction tube and located between the outer peripheral wall of the reaction tube and the inner peripheral wall of the sample tube. The diaphragm portion is located at the top of the reaction tube and is used to close the top opening of the reaction tube.

[0011] In some embodiments, the guide portion is located above the reaction tube and its outer periphery is in contact with the inner peripheral wall of the sample tube, and the guide portion has a guide channel for the puncture head to move axially.

[0012] In some embodiments, the sample tube includes a first tube body and a second tube body that are axially connected from top to bottom. A piston assembly is disposed in the first tube body, and a reaction tube is inserted into the second tube body. A first channel and a second channel are formed in the second tube body that are axially connected from top to bottom. The height of the guide portion is the same as the height of the first channel and the two are in contact. The diaphragm portion and the sleeve portion are both located in the second channel.

[0013] In some embodiments, an annular guide surface is formed on the top inner periphery of the guide portion, and the annular guide surface is an inclined surface.

[0014] In some embodiments, the inner peripheral wall of the sleeve has an annular sealing ring, which is in a sealing fit with the outer peripheral wall of the reaction tube.

[0015] In some embodiments, the diaphragm is a corrosion-resistant thermoplastic elastomer.

[0016] In some embodiments, the piston assembly further includes a puncture column disposed at the end of the piston away from the diaphragm. The puncture column extends along the axial direction of the sample tube, and the side wall of the puncture column is provided with a perforated portion. The first reagent in the sample tube can pass through the perforated portion and enter the puncture column. The puncture column is provided with an adsorbent for adsorbing impurities of the first reagent. The puncture column is used to drive the piston to move downward so that the first reagent after adsorption treatment enters the reaction tube for reaction.

[0017] In some embodiments, the puncture column has multiple adsorption pore groups on its wall for the entry of the first reagent from the sample tube. The multiple adsorption pore groups are evenly spaced along the circumference of the puncture column, and each adsorption pore group includes multiple adsorption pores evenly spaced along the axial direction of the puncture column.

[0018] In some embodiments, the sidewall of the piercing head is provided with multiple flow channels for guiding the first reagent.

[0019] The second aspect of this utility model provides a testing device, including the aforementioned testing consumables.

[0020] In the above technical solution, the testing consumables include a sample tube, a reaction tube, a diaphragm, and a piston assembly. The sample tube contains a first reagent, and the reaction tube, located below the first reagent, contains a second reagent. The sample tube and the reaction tube are detachably connected. The diaphragm is located between the reaction tube and the sample tube and isolates them. The diaphragm is detachably connected to both the sample tube and the reaction tube. The piston assembly is housed within the sample tube and includes a piston and a piercing head. The operator can push the piston to pierce the diaphragm with the piercing head, allowing the first reagent to pass through the diaphragm and enter the reaction tube to react with it. In the above testing consumables, the diaphragm is detachably connected to both the sample tube and the reaction tube, allowing each component to be stored and transported separately, making storage and transportation more convenient. Secondly, different types of sample tubes can be adapted to different types of reaction tubes, making the combination of sample tubes and reaction tubes more flexible and improving the compatibility between the various components of the consumables. Furthermore, by setting up the piston assembly, the operator can easily push the piston to pierce the diaphragm with the piercing head, realizing the reaction between the first and second reagents, making the operation simple and quick.

[0021] Other features and advantages of this invention will be described in detail in the following detailed description section. Attached Figure Description

[0022] The accompanying drawings are provided to further illustrate the embodiments of the present invention and form part of the specification. They are used together with the following detailed description to explain the embodiments of the present invention, but do not constitute a limitation thereof. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without any inventive effort. In the drawings:

[0023] Figure 1 This is a schematic diagram of the structure of the testing consumables provided according to an embodiment of the present utility model;

[0024] Figure 2 This is a cross-sectional schematic diagram of the testing consumables provided according to an embodiment of the present utility model;

[0025] Figure 3 This is a cross-sectional schematic diagram of the diaphragm provided according to an embodiment of the present utility model;

[0026] Figure 4 This is a cross-sectional schematic diagram of a sample tube provided according to an embodiment of the present utility model;

[0027] Figure 5 This is a schematic diagram of the piston assembly provided according to an embodiment of the present utility model;

[0028] Figure 6 This is a schematic diagram of the sealing component structure provided according to an embodiment of this application.

[0029] Explanation of reference numerals in the attached figures

[0030] 100 sample tubes

[0031] 110 First tube body

[0032] 120 Second tube body

[0033] 121 First Passage

[0034] 122 Second Channel

[0035] 130 Annular mounting groove

[0036] 200 reaction tube

[0037] 210 Annular Plug

[0038] 300 Piston Assembly

[0039] 310 Piston

[0040] 311 Pierced the head

[0041] 320 puncture column

[0042] 321 Adsorption pores

[0043] 330 baffle

[0044] 331 Avoidance Gap

[0045] 340 Reinforced Plate

[0046] 400 sealing components

[0047] 600 diaphragm

[0048] 610 Set-up Department

[0049] 611 Annular Seal

[0050] 620 Diaphragm Section

[0051] 630 Guiding Section

[0052] 631 Guide Surface Detailed Implementation

[0053] The specific embodiments of this utility model will be described in detail below with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are for illustration and explanation only and are not intended to limit the scope of this utility model.

[0054] The following description, with reference to the accompanying drawings, describes the testing consumables and testing equipment according to this utility model.

[0055] like Figure 1The diagram shown is a structural schematic of the testing consumables provided according to an embodiment of the present invention; as shown... Figure 2 The image shown is a cross-sectional schematic diagram of the testing consumables provided according to an embodiment of the present invention. The testing consumables provided in this embodiment of the present invention include:

[0056] Sample tube 100, used to contain the first reagent;

[0057] The reaction tube 200 is used to contain the second reagent, and the sample tube 100 is detachably connected to the reaction tube 200;

[0058] A diaphragm 600 is located between the reaction tube 200 and the sample tube 100 and is used to isolate the reaction tube 200 and the sample tube 100. The diaphragm 600 can be detachably connected to both the sample tube 100 and the reaction tube 200.

[0059] The piston assembly 300 is housed within the sample tube 100 and includes a piston 310 and a piercing head 311, the piercing head 311 being located at the bottom of the piston 310 and used to pierce the diaphragm 600.

[0060] Existing integrated testing consumables present numerous inconveniences, such as limited testing compatibility and increased transportation and storage costs. Specifically, in integrated testing consumables, the sample tube, diaphragm, and reaction tube are typically fixedly connected and cannot be separated. This design limits the consumables to testing samples only using the reagents pre-filled in the reaction tube, significantly restricting their applicability. Changing the reagent type necessitates replacing the entire consumable, undoubtedly increasing usage costs. Furthermore, integrated testing consumables face numerous challenges during transportation. Because the sample tube, diaphragm, and reaction tube are inseparable, the overall size is large, making them inconvenient to carry and transport. In addition, collisions or compression during transportation can easily damage the consumables, affecting subsequent use.

[0061] To address the aforementioned problems, this invention proposes a novel testing consumable, comprising a sample tube 100, a reaction tube 200, a diaphragm 600, and a piston assembly 300. The sample tube 100 contains a first reagent, and the reaction tube 200 contains a second reagent. The sample tube 100 and the reaction tube 200 are detachably connected. The diaphragm 600 is located between the sample tube 100 and the reaction tube 200 and serves to isolate them. The diaphragm 600 is detachably connected to both the sample tube 100 and the reaction tube 200. The piston assembly 300 has a puncture head 311 capable of puncturing the diaphragm 600. After the diaphragm 600 ruptures, the first reagent can flow from the sample tube 100 into the reaction tube 200, allowing the first reagent to react with the second reagent, facilitating medical testing of the sample. The detachable connection between sample tube 100 and reaction tube 200 allows for the compatibility of different types of sample tubes 100 and reaction tubes 200. Different types of sample tubes 100 can store different types of first reagents, and different types of reaction tubes 200 can store different types of second reagents. This enables the testing consumables provided by this invention to adapt to a wider range of tests and improves sample compatibility. Furthermore, sample tubes 100 and reaction tubes 200 can be stored and transported separately, improving transport compatibility and reducing storage and transportation costs. In addition, the detachable connection design makes replacing reaction tubes 200 and sample tubes 100 more convenient. Operators can replace different types of reaction tubes 200 and sample tubes 100 according to actual needs, improving the flexibility and applicability of the testing consumables.

[0062] The diaphragm 600 is detachably connected to both the sample tube 100 and the reaction tube 200. The connection between the diaphragm 600 and these components can be snap-fit, adhesive, or plug-in. This makes diaphragm 600 replacement more convenient. If the diaphragm 600 is damaged or contaminated during use, the operator can replace it individually without replacing the entire testing consumable, further reducing operating costs. Simultaneously, as a key component isolating the sample tube 100 and reaction tube 200, the detachable design of the diaphragm 600 ensures a tight seal between them, preventing the first and second reagents from mixing without proper treatment, thus guaranteeing the accuracy and reliability of the test. Furthermore, this testing consumable design simplifies and accelerates the reaction process between the first and second reagents. The operator only needs to push the piston 310 to puncture the diaphragm 600 with the piercing head 311, achieving rapid mixing and reaction of the first and second reagents. This design not only improves work efficiency but also reduces operational difficulty, making the testing consumables easier to promote and apply. The first reagent can be a processing solution, and the second reagent can be a reaction reagent.

[0063] In one embodiment, such as Figure 3 The diagram shown is a cross-sectional view of the diaphragm 600 provided according to an embodiment of the present invention. The outer periphery of the reaction tube 200 is engaged with the inner peripheral wall of the sample tube 100. The diaphragm 600 includes a sleeve portion 610, a diaphragm portion 620, and a guide portion 630 connected in sequence. The sleeve portion 610 is sleeved on the outer periphery of the reaction tube 200 and located between the outer peripheral wall of the reaction tube 200 and the inner peripheral wall of the sample tube 100. The diaphragm portion 620 is located at the top of the reaction tube 200 and is used to close the top opening of the reaction tube 200. The top opening of the reaction tube 200 is inserted into the inner periphery of the sample tube 100, and the outer periphery of the reaction tube 200 is engaged with the inner peripheral wall of the sample tube 100. The diaphragm 600 includes a sleeve portion 610, a diaphragm portion 620, and a guide portion 630 connected in sequence. The sleeve portion 610 is sleeved on the outer periphery of the reaction tube 200 and located between the outer peripheral wall of the reaction tube 200 and the inner peripheral wall of the sample tube 100 to achieve a stable connection between the diaphragm 600 and the reaction tube 200 and the sample tube 100. The diaphragm portion 620 is located at the top of the reaction tube 200 and fits tightly against the top opening of the reaction tube 200, effectively isolating the liquid inside the reaction tube 200 and the sample tube 100, preventing unreacted first reagent from entering the reaction tube 200, and ensuring the accuracy of the detection.

[0064] In one embodiment, the detachable connection between the sample tube 100 and the reaction tube 200 can also be a threaded connection or a magnetic connection, etc. These connection methods can achieve a stable and detachable connection between the sample tube 100 and the reaction tube 200, which is convenient for operators to assemble and disassemble.

[0065] When using threaded connections, one end of the sample tube 100 and the other end of the reaction tube 200 can be fitted with an internal thread, and the other with a matching external thread. A tight connection can be achieved by rotating the sample tube 100 or the reaction tube 200. This connection method is simple in structure, stable in connection, and easy to disassemble and replace.

[0066] When using magnetic connection, magnetic materials can be placed at the ports of sample tube 100 and reaction tube 200, allowing them to be connected through magnetic attraction. This connection method requires no additional mechanical structure, is convenient, and can accommodate sample tubes 100 and reaction tubes 200 of different shapes and sizes.

[0067] Regardless of the connection method used, the testing consumables provided by this invention can achieve a stable and detachable connection between the sample tube 100 and the reaction tube 200, thereby ensuring the stability and reliability of the testing consumables during transportation, storage, and use. Furthermore, this detachable design provides users with more choices and flexibility, allowing them to freely combine different sample tubes 100 and reaction tubes 200 according to actual needs to adapt to a wider range of testing requirements.

[0068] In one embodiment, the guide portion 630 is located above the reaction tube 200 and its outer periphery is in close contact with the inner peripheral wall of the sample tube 100. The guide portion 630 has a guide channel for the piercing head 311 to move axially. The guide portion 630, located above the reaction tube 200 and with its outer periphery tightly fitted to the inner peripheral wall of the sample tube 100, forms a guide channel for the piercing head 311 to move axially, guiding the piercing head 311 to accurately pierce the diaphragm portion 620, allowing the first reagent to flow smoothly into the reaction tube 200. This design not only improves the stability of the diaphragm 600 assembly but also ensures the high efficiency and accuracy of the reaction between the first and second reagents.

[0069] In one embodiment, such as Figure 4The diagram shown is a cross-sectional view of a sample tube 100 provided according to an embodiment of the present invention. The sample tube 100 includes a first tube body 110 and a second tube body 120 axially connected from top to bottom. A piston assembly 300 is disposed within the first tube body 110, and a reaction tube 200 is inserted into the second tube body 120. A first channel 121 and a second channel 122 are formed axially connected from top to bottom within the second tube body 120. The height of the guide portion 630 is the same as the height of the first channel 121, and the two are in contact. The diaphragm portion 620 and the sleeve portion 610 are both located within the second channel 122. The sample tube 100 is designed to include a first tube body 110 and a second tube body 120 axially connected from top to bottom. This design helps to achieve a reasonable layout of the internal structure of the testing consumables and effective management of the first reagent. A piston assembly 300 is disposed within the first tube body 110. The piston 310 portion of the piston assembly 300 can move axially within the sample tube 100, thereby facilitating the application of a puncture force to the diaphragm 600. Meanwhile, the reaction tube 200 is inserted into the second tube body 120. This insertion method is not only stable but also easy to adapt to different models of reaction tubes 200 to meet different detection needs. Within the second tube body 120, a first channel 121 and a second channel 122 are formed, connected sequentially from top to bottom along the axial direction. This channel design facilitates the orderly flow of the first reagent during the detection process. The guide portion 630 has the same height as the first channel 121, and the two fit tightly together. This design ensures that the guide portion 630 can stably guide the piercing head 311 along the axial direction, avoiding deviation during piercing. Simultaneously, the guide portion 630 also prevents the sample tube 100 from being corrosive or strongly alkaline liquids in the first reagent, ensuring that the reaction tube 200 can store the first reagent for a longer period. Both the diaphragm section 620 and the sleeve section 610 are located within the second channel 122. This arrangement allows the diaphragm 600 to effectively isolate the reaction tube 200 and the sample tube 100, preventing the first reagent from entering the reaction tube 200 without processing, thereby ensuring the accuracy of the detection.

[0070] In one embodiment, such as Figure 2 As shown, the reaction tube 200 is a conical tube. This design helps to distribute the first reagent evenly within the reaction tube 200, improves the reaction efficiency between the first and second reagents, and thus enhances the sensitivity and accuracy of the detection.

[0071] In one embodiment, such as Figure 2As shown, the outer periphery of the reaction tube 200 is provided with an annular insertion portion 210, and the inner peripheral wall of the sample tube 100 is provided with an annular mounting groove 130. When assembling the testing consumables, the diaphragm 600 is first placed on the top opening of the reaction tube 200, and then the sample tube 100 is placed on the diaphragm 600. The annular mounting groove 130 of the sample tube 100 and the annular insertion portion 210 of the reaction tube 200 cooperate with each other, so that the sample tube 100 and the reaction tube 200 can be stably connected together.

[0072] In one embodiment, such as Figure 3 As shown, an annular guide surface 631 is formed on the inner periphery of the top of the guide portion 630, and the annular guide surface 631 is an inclined surface. The inclined surface can further guide the piercing head 311, so that the piercing head 311 can move precisely along the axial direction of the sample tube 100 and pierce the diaphragm portion 620 downward.

[0073] In one embodiment, such as Figure 3 As shown, the inner peripheral wall of the sleeve 610 has an annular sealing ring 611, which seals against the outer peripheral wall of the reaction tube 200. The annular sealing ring 611 effectively prevents the first reagent from leaking through the gap between the diaphragm 600 and the reaction tube 200, ensuring that the first reagent flows completely into the reaction tube 200 to react with the second reagent, further improving the accuracy and reliability of the detection. Furthermore, the design of the annular sealing ring 611 enhances the connection stability between the diaphragm 600 and the reaction tube 200, avoiding problems such as diaphragm 600 detachment or displacement due to pressure from the first reagent or improper operation.

[0074] In one embodiment, the diaphragm 600 is a corrosion-resistant thermoplastic elastomer. Corrosion-resistant thermoplastic elastomers possess excellent corrosion resistance and elasticity, effectively resisting the corrosion of the first reagent while ensuring the flexibility and durability of the diaphragm 600. This material selection not only extends the service life of the diaphragm 600 but also improves the reliability and durability of the entire testing consumable, enabling it to operate stably in various harsh environments and ensuring the accuracy and reliability of the tests. Specifically, the corrosion-resistant thermoplastic elastomer is made of TPE material.

[0075] In one embodiment, such as Figure 5The diagram shows a schematic of the piston assembly 300 according to an embodiment of the present invention. The piston assembly 300 also includes a puncture column 320, which is located at the end of the piston 310 away from the diaphragm 600. The puncture column 320 extends along the axial direction of the sample tube 100. A perforated portion is provided on the side wall of the puncture column 320, allowing the first reagent in the sample tube 100 to pass through the perforated portion and enter the puncture column 320. An adsorbent (not shown) for adsorbing impurities in the first reagent is provided inside the puncture column 320. The puncture column 320 drives the piston 310 downwards, allowing the adsorbed first reagent to enter the reaction tube 200 for reaction. The puncture column 320 is located at the end of the piston 310 away from the diaphragm 600 and extends along the axial direction of the sample tube 100. The perforated portion design not only allows the first reagent in the sample tube 100 to smoothly enter its interior but also provides an adsorbent inside. The main function of the adsorption element is to adsorb and remove impurities in the first reagent, such as proteins and lipids that do not need to be detected, thereby ensuring the purity of the first reagent, achieving the effect of pretreatment, and improving the accuracy of detection.

[0076] The puncture column 320 not only serves as a carrier for the adsorbent, but also plays another important role: driving the piston 310 downwards. As the puncture column 320 moves downwards, it pushes the piston 310 downwards until the puncture head 311 punctures the diaphragm 600. This design allows the first reagent, after adsorption treatment, to accurately enter the reaction tube 200 and react with the second reagent therein, thereby greatly improving the efficiency and accuracy of the detection.

[0077] In one embodiment, the puncture column 320 has multiple adsorption pore groups on its wall for the entry of the first reagent from the sample tube 100. These adsorption pore groups are evenly spaced along the circumference of the puncture column 320, and each group includes multiple adsorption holes 321 evenly spaced along the axial direction of the puncture column 320. This design allows the first reagent to enter the puncture column 320 more uniformly, increasing the contact opportunity between the first reagent and the adsorption element, thereby improving the impurity removal efficiency. Furthermore, the evenly distributed adsorption pore groups help maintain pressure balance within the puncture column 320, preventing excessive resistance during the entry of the first reagent and ensuring smooth flow of the first reagent.

[0078] In one embodiment, such as Figure 5As shown, the piston assembly 300 further includes a baffle 330, which is sleeved on the outer periphery of the puncture column 320 and slides in contact with the inner peripheral wall of the sample tube 100. Multiple adsorption pores are located between the baffle 330 and the piston 310. The baffle 330 has multiple clearance notches 331. The baffle 330 can slide in contact with the inner wall of the sample tube 100. When the puncture column 320 moves up and down, the baffle 330 can guide and limit the movement of the puncture column 320, ensuring that the movement direction of the puncture column 320 is axial, preventing the puncture head 311 from deviating from the diaphragm 600. Furthermore, the multiple clearance notches 331 on the baffle 330 facilitate airflow up and down, allowing the puncture column 320 to move more smoothly. The multiple adsorption pores 321 located between the baffle 330 and the piston 310 allow the first reagent to pass more smoothly through the adsorption pores into the puncture column 320, ensuring the smooth flow of the first reagent. The presence of baffle 330 also enhances the structural stability of piston assembly 300, making its movement within sample tube 100 smoother and more reliable.

[0079] In one embodiment, such as Figure 5 As shown, the piston assembly 300 also includes multiple reinforcing plates 340 connected between the bottom of the baffle 330 and the outer peripheral wall of the puncture post 320. The multiple reinforcing plates 340 increase the connection strength between the baffle 330 and the puncture post 320, preventing the baffle 330 from deforming or being damaged during the movement of the piston assembly 300, further improving the structural stability and durability of the piston assembly 300. The design of the reinforcing plates 340 also takes into account weight reduction, minimizing their impact on the overall weight of the piston assembly 300 and ensuring that the piston assembly 300 can respond flexibly and quickly to operations.

[0080] In one embodiment, such as Figure 6 The diagram shows a schematic of the sealing element 400 provided according to an embodiment of this application. A sealing element 400 is provided on the top cap of the sample tube 100. The sealing element 400 abuts against the top end of the puncture column 320. The sealing element 400 applies an axial force to the puncture column 320, causing it to move downwards. The sealing element 400 is used to seal the top space of the sample tube 100, preventing leakage of the first reagent during movement. The sealing element 400 abuts against the top end of the puncture column 320, enabling it to move the puncture column 320 downwards, allowing the puncture head 311 to puncture the diaphragm 600. The first reagent in the sample tube 100 passes through the diaphragm 600 and reacts with the second reagent in the reaction tube 200 for sample detection.

[0081] In one embodiment, the sidewall of the piercing head 311 is provided with multiple flow channels (not shown in the figure) for guiding the first reagent. If the cross-section of the piercing head 311 is a convex polygon or a circle, it will be difficult for the first reagent to flow into the gap between the diaphragm 600 and the piercing head 311 after the piercing head 311 pierces the diaphragm 600. Based on this technical problem, this application provides multiple flow channels for guiding the first reagent on the sidewall of the piercing head 311. After the piercing head 311 pierces the diaphragm 600, the first reagent can flow along the flow channels into the reaction tube 200 to react. Using the above-described piercing head 311, the first reagent can be introduced into the reaction tube 200 more smoothly, avoiding the problem of low detection efficiency caused by poor flow of the first reagent.

[0082] In one specific embodiment, there are two guide grooves, which are respectively arranged opposite to each other on both sides of the piercing head 311. Both guide grooves are arc-shaped and concave inward toward the axis of the piercing head 311.

[0083] In one specific embodiment, when the first reagent needs to be tested, the first reagent is stored in the sample tube 100, the second reagent is stored in the reaction tube 200, the diaphragm 600 is installed at the bottom of the sample tube 100, and the sample tube 100 is placed over the reaction tube 200. The piston assembly 300 is inserted, allowing the first reagent to flow from the adsorption hole 321 into the puncture column 320. The adsorption element in the puncture column 320 can adsorb and pre-treat the proteins and lipids in the first reagent to increase the purity of the first reagent. After a period of pre-treatment, adsorption is confirmed to be complete. The sealing element 400 is pushed, which drives the puncture column 320 downward. Subsequently, the piston 310 moves downward along the guide channel of the guide portion 630, separating the quantitative first reagent from the first reagent above the piston 310. The piston 310 continues to move downward, causing the puncture head 311 to puncture the diaphragm 600, allowing the first reagent to flow into the reaction tube 200 along the guide groove of the puncture head 311. The above steps are simple to operate and effectively pre-treat, aspirate, and dispense the first reagent, completing the entire detection process. This integrated design not only simplifies the operation but also reduces the use of consumables, lowering costs. Furthermore, since all steps are completed within a single detection consumable, it reduces the potential contamination of the first reagent during transfer, improving detection accuracy.

[0084] In the description of this utility model, it should be understood that the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this utility model, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0085] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection, an electrical connection, or a connection that allows communication between them; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise explicitly limited. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0086] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0087] Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention. Those skilled in the art can make changes, modifications, substitutions and variations to the above embodiments within the scope of the present invention.

Claims

1. A detection consumable, characterized in that, The testing consumables include: Sample tube (100) for containing the first reagent; A reaction tube (200) is used to contain a second reagent, and the sample tube (100) is detachably connected to the reaction tube (200); A diaphragm (600) is located between the reaction tube (200) and the sample tube (100) and is used to isolate the reaction tube (200) and the sample tube (100). The diaphragm (600) is detachably connected to both the sample tube (100) and the reaction tube (200). A piston assembly (300) is housed within the sample tube (100) and includes a piston (310) and a piercing head (311), the piercing head (311) being located at the bottom of the piston (310) and used to pierce the diaphragm (600).

2. The test consumable of claim 1, wherein, The outer periphery of the reaction tube (200) is engaged with the inner peripheral wall of the sample tube (100). The diaphragm (600) includes a sleeve portion (610), a diaphragm portion (620), and a guide portion (630) connected in sequence. The sleeve portion (610) is sleeved on the outer periphery of the reaction tube (200) and located between the outer peripheral wall of the reaction tube (200) and the inner peripheral wall of the sample tube (100). The diaphragm portion (620) is located at the top of the reaction tube (200) and is used to close the top opening of the reaction tube (200).

3. The test consumable of claim 2, wherein, The guide portion (630) is located above the reaction tube (200) and its outer periphery is in contact with the inner peripheral wall of the sample tube (100). The guide portion (630) has a guide channel for the puncture head (311) to move axially.

4. The testing consumables according to claim 3, characterized in that, The sample tube (100) includes a first tube body (110) and a second tube body (120) that are axially connected from top to bottom. The piston assembly (300) is disposed in the first tube body (110). The reaction tube (200) is inserted into the second tube body (120). The second tube body (120) forms a first channel (121) and a second channel (122) that are axially connected from top to bottom. The guide part (630) has the same height as the first channel (121) and the two are in contact. The diaphragm part (620) and the sleeve part (610) are both located in the second channel (122).

5. The test consumable of claim 2, wherein, The top inner periphery of the guide portion (630) is formed with an annular guide surface (631), which is an inclined surface.

6. The test consumable of claim 2, wherein, The inner peripheral wall of the sleeve (610) has an annular sealing ring (611), which is in a sealing fit with the outer peripheral wall of the reaction tube (200).

7. The test consumable of claim 1, wherein, The diaphragm (600) is a corrosion-resistant thermoplastic elastic component.

8. The test consumable of claim 1, wherein, The piston assembly (300) also includes: A puncture column (320) is disposed at the end of the piston (310) opposite to the diaphragm (600). The puncture column (320) extends along the axial direction of the sample tube (100). The side wall of the puncture column (320) is provided with a perforated portion, through which the first reagent in the sample tube (100) can pass into the puncture column (320). The puncture column (320) is provided with an adsorbent for adsorbing impurities of the first reagent. The piston (310) is used to move downward so that the first reagent after adsorption treatment enters the reaction tube (200) for reaction. The puncture column (320) has a plurality of adsorption holes on its wall for the first reagent in the sample tube (100) to enter. The plurality of adsorption holes are evenly spaced along the circumference of the puncture column (320). Each adsorption hole group includes a plurality of adsorption holes (321) evenly spaced along the axial direction of the puncture column (320).

9. The test consumable of claim 1, wherein, The sidewall of the piercing head (311) is provided with multiple flow channels for guiding the first reagent.

10. A detection device, characterized by The testing consumables include any one of claims 1 to 9.

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