An atomizing quick-freezing system

Abstract

This utility model discloses an atomization quick-freezing system, which atomizes materials through nozzles by pressurization, and controls a robotic arm to evenly spray the atomized materials onto a tray placed on a freezing box. The freezing box then quickly freezes the atomized materials. This provides a quick-freezing device for the production of high specific surface area nanoscale slow-release powders, with high production efficiency and stable product quality.

Description

Technical Field

[0001] This utility model relates to a quick-freezing device for the production of high specific surface area nanoscale slow-release micro powders. Background Technology

[0002] Polypeptide biopharmaceuticals possess advantages such as high bioactivity, no toxic side effects after degradation, and direct administration. However, blood drug concentrations are affected by the dosage form and route of administration, necessitating the search for a slow-release dosage form or route of administration. Experiments have shown that increasing the specific surface area of ​​a drug decreases its solubility, achieving a sustained-release effect. Currently, nanoscale sustained-release particle dosage forms have been developed for nasal administration, resulting in good absorption and a slow release of peak blood drug concentration, thus achieving a sustained-release effect. Existing quick-freezing equipment suffers from limitations in robotic arm operation and is not waterproof, corrosion-resistant, or explosion-proof.

[0003] The purpose of this invention is to provide a quick-freezing device for the efficient and stable production of high specific surface area nanoscale slow-release micro powders. Utility Model Content

[0004] The technical problem to be solved by this utility model is to provide a quick-freezing device for the production of high specific surface area nanoscale slow-release powders, and the technical solution is as follows:

[0005] A quick-freezing atomizing system includes a frame assembly, a tray, a robotic arm, a solenoid valve, a nozzle, a hose, a storage tank, and a control cabinet. The frame assembly comprises a frame and a freezing chamber, the freezing chamber being a recessed structure. The tray is placed in the recess of the freezing chamber. The robotic arm is bolted to the frame assembly. The nozzle is connected to the solenoid valve and fixed to the robotic arm. The hose connects the solenoid valve to the storage tank. The control cabinet controls the robotic arm's movement, detects the liquid level and pressure inside the freezing chamber, and detects the internal pressure of the storage tank.

[0006] Preferably, the freezer is equipped with a liquid nitrogen chamber and an outer insulation chamber for the liquid nitrogen chamber. The liquid nitrogen chamber has four ports: a liquid nitrogen inlet, an exhaust port, a level gauge port, and a safety valve port.

[0007] Preferably, the liquid nitrogen inlet is equipped with an on / off valve.

[0008] Preferably, the liquid level gauge port is equipped with a liquid level gauge and has a temperature detection function.

[0009] Preferably, the safety valve port is connected to both the safety valve and the pressure sensor.

[0010] Preferably, a platform is provided between the bottom of the recessed structure of the freezer and the tray, and the upper surface of the platform is flat and smooth.

[0011] Preferably, the tray has a hollowed-out cuboid structure at the top, a flat and smooth bottom, and the number of trays is ≥1.

[0012] Preferably, the robotic arm has an axis linkage structure, and a nozzle and a solenoid valve are installed at the front end of the robotic arm.

[0013] Preferably, the storage tank is equipped with an air inlet, and the spray pipe is equipped with a small-diameter nozzle.

[0014] The advantages of this utility model are as follows:

[0015] This invention atomizes materials through a nozzle by applying pressure. The control cabinet controls a robotic arm to evenly spray the atomized material onto a tray placed in a freezing box. The freezing box then quickly freezes the atomized material. The multi-axis linkage robotic arm provides higher control precision, a wider adjustment range, higher production efficiency, stable product quality, and better waterproof and corrosion-resistant properties. Attached Figure Description

[0016] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0017] Figure 1 This is a schematic cross-sectional view of the freezer box according to an embodiment of the present invention;

[0018] Figure 2 This is a schematic diagram of the atomized quick-freezing system according to an embodiment of the present invention;

[0019] In the diagram: 1-Frame assembly; 2-Refrigeration chamber; 3-Liquid nitrogen valve; 4-Level gauge; 5-Safety valve; 6-Pressure sensor; 7-Solenoid valve; 8-Robot arm; 9-Spray nozzle; 10-Nozzle; 11-Tray; 12-Hose; 13-Storage tank; 14-Control cabinet; 15-Platform; 16-Insulated cavity; 17-Liquid nitrogen cavity. Detailed Implementation

[0020] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0021] To make the above-mentioned objectives, features and advantages of this utility model more apparent and understandable, the utility model will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0022] like Figure 1 As shown, this embodiment provides an atomizing quick-freezing system, including a frame assembly 1, a tray 11, a robotic arm 8, a solenoid valve 7, a spray pipe 9, a nozzle 10, a hose 12, a storage tank 13, and a control cabinet 14. The main body of the frame assembly 1 includes a frame and a freezing chamber 2. The frame and the freezing chamber 2 are connected by welding. The freezing chamber 2 is configured as a recessed structure, and a platform 15 is set on the upper surface of the bottom of the recessed structure. The tray 11 is placed in the recess of the freezing chamber 2. The tray 11 is a rectangular structure with a hollow top for storing materials. The upper surface of the platform 15 and the bottom of the tray 11 should be kept flat and smooth to facilitate a better fit and a larger contact area when the tray 11 contacts the platform 15, thereby ensuring the tray... The cooling conduction effect of unit 11 is achieved using 316L stainless steel trays, with a maximum of one tray. The freezer 2 is equipped with a liquid nitrogen chamber 17 and an external insulation chamber 16. The liquid nitrogen chamber 17 stores liquid nitrogen, and the insulation chamber 16 maintains the liquid nitrogen temperature. The liquid nitrogen chamber 17 has four ports: a liquid nitrogen inlet, an exhaust port, a level gauge port, and a safety valve port. The liquid nitrogen inlet is equipped with a liquid nitrogen valve 3. The exhaust port is used to expel air from the liquid nitrogen chamber when adding liquid nitrogen. The level gauge port is equipped with a level gauge 4 to detect the liquid level in the chamber and also has a temperature detection function. The safety valve port is connected to a safety valve 5 and a pressure sensor 6. Liquid nitrogen can be automatically added to the freezer 2 via liquid... The level gauge 4 detects the liquid nitrogen level and sets a target liquid level height. If the liquid level is lower than the target height, the liquid nitrogen valve 3 automatically opens to add liquid nitrogen. Once the target liquid level is reached, the valve automatically closes. The freezer 2 is equipped with a pressure sensor 6. When the internal pressure reaches the set value, the liquid nitrogen valve 3 automatically closes. When the internal pressure of the freezer 2 reaches the value set by the safety valve 5, the safety valve 5 automatically opens to release pressure. The robot arm 8 is fixed to the frame assembly 1 by bolts. The robot arm 8 has a linkage structure, preferably a six-axis linkage, but not limited to six-axis linkage. The robot arm 8 has certain corrosion resistance, waterproof performance, and low-temperature working capability. The front end of the robot arm 8 is equipped with a nozzle 9 and a solenoid valve 7, which can drive the nozzle 9 to deliver materials. The material is evenly sprayed on the inside of the tray 11, and the speed and stroke can be adjusted as needed. The spray pipe 9 is connected to the solenoid valve 7, and the hose 12 connects the solenoid valve 7 to the storage tank 13. The storage tank 13 is equipped with an air inlet. The material inside the storage tank 13 is transferred to the spray pipe 9 through the hose 12 by pressurization. The lower end of the spray pipe 9 is connected to a nozzle 10. The material is sprayed onto the inside of the tray 11 through the nozzle 10 installed at the bottom of the spray pipe 9 for quick freezing. The nozzle 10 is a small-diameter nozzle that can atomize the pressurized liquid. The atomized material is evenly sprayed on the tray. The control cabinet 14 is used to control the robot arm 8 to run along the prescribed route, and to detect the liquid level and pressure inside the freezer 2 and the internal pressure of the storage tank 13.

[0023] In practical use, the liquid nitrogen valve 3, level gauge 4, pressure sensor 6 and solenoid valve 7 are controlled by the control cabinet 14. The liquid nitrogen valve 3 is opened and liquid nitrogen is added from the liquid nitrogen inlet of the freezing box 2. The liquid nitrogen level target height is set by the level gauge 4. When the liquid nitrogen is added to the target position, the liquid nitrogen valve 3 is closed. The tray 11 is placed on the platform 15 and air is pumped into the air inlet of the storage tank 13 to form a certain pressure inside the storage tank 13. The robot arm 8 is controlled to run according to the set route and speed. At the same time, the solenoid valve 7 is opened and the material is evenly sprayed into the tray 11 under pressure for quick freezing. After quick freezing, the tray 11 is placed in the freeze dryer for drying.

[0024] This specification uses specific examples to illustrate the principles and implementation methods of this utility model. The descriptions of the above embodiments are only for the purpose of helping to understand the method and core ideas of this utility model. At the same time, for those skilled in the art, there will be changes in the specific implementation methods and application scope based on the ideas of this utility model. In summary, the content of this specification should not be construed as a limitation of this utility model.

Claims

1. An atomized flash freezing system comprising a gantry assembly, a tray, a robot, a solenoid valve, a spray tube, a hose, a reservoir, and a control cabinet, characterized in that: The frame assembly includes a frame and a freezing chamber. The freezing chamber is configured with a recessed structure. The tray is placed in the recess of the freezing chamber. The robot arm is fixed to the frame assembly by bolts. The nozzle is connected to a solenoid valve and fixed to the robot arm. A hose connects the solenoid valve to the storage tank. The control cabinet controls the robot arm's running path, detects the liquid level and pressure inside the freezing chamber, and detects the internal pressure of the storage tank.

2. The atomized flash freezing system of claim 1, wherein: The freezer is equipped with a liquid nitrogen chamber and an outer insulation chamber. The liquid nitrogen chamber has four ports: a liquid nitrogen inlet, an exhaust port, a level gauge port, and a safety valve port.

3. The atomized flash freezing system of claim 2, wherein: The liquid nitrogen inlet is equipped with an on / off valve.

4. The atomized flash freezing system of claim 2, wherein: The liquid level gauge port is equipped with a liquid level gauge and has a temperature detection function.

5. The atomized flash freezer system of claim 2, wherein: The safety valve port is connected to a safety valve and a pressure sensor.

6. The atomized flash freezing system of claim 1, wherein: The freezer has a platform between the bottom of the groove structure and the tray, and the upper surface of the platform is flat and smooth.

7. The atomized flash freezing system of claim 1, wherein: The pallet has a hollowed-out cuboid structure at the top and a flat and smooth bottom. The number of pallets is ≥1.

8. The atomized flash freezing system of claim 1, wherein: The robotic arm has an axis linkage structure, and a nozzle and a solenoid valve are installed at the front end of the robotic arm.

9. The atomized flash freezing system of claim 1, wherein: The storage tank is equipped with an air inlet, and the nozzle is equipped with a small-diameter nozzle.

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