Heparin sodium freeze drying equipment
By designing the feeding mechanism and microwave generator for the freeze-drying equipment, the problem of uneven heating in the heparin sodium freeze-drying device was solved, achieving uniform drying of heparin sodium and convenient operation of the equipment, thus improving the drying effect.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- NANTONG TIANRUI BIOLOGICAL TECH CO LTD
- Filing Date
- 2025-06-05
- Publication Date
- 2026-07-31
AI Technical Summary
In existing heparin sodium freeze-drying equipment, the heparin sodium is subjected to uneven heat radiation after freezing, resulting in unsatisfactory drying effect.
A heparin sodium freeze-drying device was designed, comprising a freezing chamber and a drying chamber. Utilizing a feeding mechanism and a microwave generator, the feeding motor and rotary motor drive the material cylinder to rotate, ensuring uniform contact between the product and the microwave. The rotation of the active and driven discs is achieved through magnetic coupling. Combined with the design of a sealed door, the device improves operational flexibility and convenience.
This method achieves uniform drying of heparin sodium, improves the drying effect, and enhances the ease of use and flexibility of the equipment.
Smart Images

Figure CN224580572U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of heparin sodium processing technology, specifically to heparin sodium freeze-drying equipment. Background Technology
[0002] In the processing and production of heparin sodium, a vacuum freeze-drying device is used to freeze the moisture in the heparin sodium, and then directly sublimate it from solid to gas under vacuum to complete the drying. In the existing technology, the heparin sodium freeze-drying device does not receive uniform heat radiation after freezing, resulting in an unsatisfactory drying effect.
[0003] For example, patent publication number CN209940879U describes a drying device for preparing sodium heparin, including a drying chamber, a freezing device, and a vacuum device. The drying chamber is divided into a freezing chamber, a buffer chamber, and a drying chamber. A conveyor belt is installed inside the drying chamber. The freezing chamber is connected to the freezing device via a pipe and has an inlet. The collection tank is connected to a cold energy recovery device. The drying chamber has an outlet and is connected to the vacuum device via a vacuum pipe. A microwave transmitter is installed inside the drying chamber. The drying chamber is divided into a freezing chamber and a drying chamber. The moisture in the material is first condensed into ice crystals, and then heated to directly sublimate into gas, reducing the amount of condensate produced during the drying process. Microwave heating directly heats the material, avoiding heat loss and ensuring a uniform temperature inside the drying chamber, further reducing condensate production. Through freezing in the freezing chamber and microwave heating in the drying chamber, sodium heparin can be fully dried. However, this sodium heparin freeze-drying device has a problem: the degree of heat radiation received by the frozen sodium heparin is uneven, resulting in an unsatisfactory drying effect. Utility Model Content
[0004] To address the shortcomings of existing technologies, this invention provides a heparin sodium freeze-drying device, which solves the problem that the heparin sodium is not heated evenly after freezing, resulting in an unsatisfactory drying effect.
[0005] To achieve the above objectives, this utility model is implemented through the following technical solution: a heparin sodium freeze-drying device, comprising a body, wherein a freezing chamber and a drying chamber are provided inside the body, a feeding mechanism is provided between the freezing chamber and the drying chamber, a microwave generator is installed inside the drying chamber, and a switching mechanism is provided on the front side of the body;
[0006] The feeding mechanism includes a guide rod and a feeding screw. A feeding motor is fixedly connected to the top of the feeding screw. A top sealing plate is threaded onto the feeding screw. The guide rod is slidably connected to the top sealing plate. Multiple connecting rods are fixedly connected to the bottom of the top sealing plate. A bottom sealing plate is fixedly connected to the bottom of the multiple connecting rods. A placement seat is rotatably connected to the bottom sealing plate. A material cylinder is snapped into the top of the placement seat. A connecting shaft is fixedly connected to the bottom of the placement seat. A driven disk is fixedly connected to the bottom of the connecting shaft. An active disk is provided at the bottom of the driven disk. A rotary motor is fixedly connected to the bottom of the active disk. Multiple first magnets are fixedly connected to the active disk. Multiple second magnets are fixedly connected to the driven disk.
[0007] Preferably, the guide rod is fixedly installed inside the freezing chamber, and the feeding screw is rotatably connected to the inner wall of the freezing chamber, so that the guide rod can guide the movement of the top sealing plate.
[0008] Preferably, a passage is provided between the freezing chamber and the drying chamber, and the area of the passage is smaller than the area of the top sealing plate and the bottom sealing plate, so that the passage can be sealed by the top sealing plate and the bottom sealing plate.
[0009] Preferably, the top sealing plate and the bottom sealing plate are respectively disposed inside the freezing chamber and the drying chamber, and the drying chamber is disposed at the bottom of the freezing chamber, so that the frozen product can be sent into the drying chamber for drying.
[0010] Preferably, the rotary motor is fixedly installed inside the machine body, and the output shaft end of the rotary motor is fixedly connected to the drive disk, so that the rotary motor can drive the drive disk to rotate.
[0011] Preferably, the plurality of first magnets and the plurality of second magnets are each configured as two sets of magnets, and the magnetic poles of each set of magnets are set to opposite magnetic poles from top to bottom. The two sets of magnets are arranged alternately so that the first magnets and the second magnets can attract each other and achieve magnetic coupling, thereby enabling the active disk to drive the driven disk to rotate.
[0012] Preferably, the switching mechanism includes a main sealing door with a main handle fixedly connected to it. One end of the main sealing door is rotatably connected to the machine body. Two sub-sealing doors are rotatably connected inside the main sealing door. Each of the two sub-sealing doors has a separate handle fixedly connected to it. Both the main sealing door and the sub-sealing doors are equipped with sealing strips, which allows for easy opening of the freezing chamber and the drying chamber separately, as well as opening of the whole machine, effectively improving the flexibility and convenience of use.
[0013] This invention provides a freeze-drying apparatus for heparin sodium. Compared with the prior art, it has the following advantages:
[0014] 1. This heparin sodium freeze-drying equipment involves placing heparin sodium into a material cylinder, freezing it with liquid nitrogen inside the freezing chamber, and then having the material cylinder delivered to the drying chamber by a feeding motor. A microwave generator dries the product, while a rotating motor drives the placement seat to rotate, which in turn drives the material cylinder to rotate. This ensures that the product comes into uniform contact with the microwaves emitted by the microwave generator, thereby effectively improving the drying effect.
[0015] 2. This heparin sodium freeze-drying equipment allows for easy opening of the freezing chamber and drying chamber via two separate sealed doors, while the entire unit can be opened via a main sealed door, effectively improving the flexibility and convenience of use. Attached Figure Description
[0016] Figure 1 This is a schematic diagram of the overall structure of this utility model.
[0017] Figure 2 This is a schematic diagram of the feeding mechanism of this utility model.
[0018] Figure 3 This is a schematic diagram of the active and driven disks of this utility model.
[0019] Figure 4 This is a schematic diagram of the switching mechanism structure of this utility model.
[0020] In the diagram: 1. Machine body; 2. Feeding mechanism; 201. Guide rod; 202. Feeding screw; 203. Top sealing plate; 204. Feeding motor; 205. Connecting rod; 206. Bottom sealing plate; 207. Placement seat; 208. Material cylinder; 209. Connecting shaft; 210. Driven disc; 211. Second magnet; 212. First magnet; 213. Driven disc; 214. Rotary motor; 3. Drying chamber; 4. Switching mechanism; 401. Main sealing door; 402. Main handle; 403. Sub-sealing door; 404. Sub-handle; 405. Sealing strip; 5. Freezing chamber; 6. Microwave generator. Detailed Implementation
[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0022] Please see Figure 1-3This utility model provides a technical solution: a heparin sodium freeze-drying equipment, including a body 1. The body 1 is equipped with a vacuum device that can evacuate the freezing chamber 5 and the drying chamber 3. The body 1 contains the freezing chamber 5 and the drying chamber 3. The freezing chamber 5 has a nozzle that can spray liquid nitrogen for freezing. A feeding mechanism 2 is provided between the freezing chamber 5 and the drying chamber 3. A microwave generator 6 is installed inside the drying chamber 3. A switching mechanism 4 is provided on the front side of the body 1. The heparin sodium product can be conveyed through the feeding mechanism 2 and can be rotated so that the product comes into uniform contact with the microwaves emitted by the microwave generator 6, thereby effectively improving the drying effect.
[0023] The feeding mechanism 2 includes a guide rod 201 and a feeding screw 202. The guide rod 201 is fixedly installed inside the freezing chamber 5, and the feeding screw 202 is rotatably connected to the inner wall of the freezing chamber 5, so that the guide rod 201 can guide the movement of the top sealing plate 203. A feeding motor 204 is fixedly connected to the top end of the feeding screw 202, and the top sealing plate 203 is threadedly connected to the feeding screw 202. The guide rod 201 is slidably connected to the top sealing plate 203, and multiple connecting rods are fixedly connected to the bottom end of the top sealing plate 203. 205. Multiple connecting rods 205 are fixedly connected to a bottom sealing plate 206 at their bottom ends. A passage is provided between the freezing chamber 5 and the drying chamber 3. The area of the passage is smaller than the area of the top sealing plate 203 and the bottom sealing plate 206, so that the top sealing plate 203 and the bottom sealing plate 206 can seal the passage. The top sealing plate 203 and the bottom sealing plate 206 are respectively installed inside the freezing chamber 5 and the drying chamber 3. The drying chamber 3 is located at the bottom of the freezing chamber 5, so that the frozen product can be sent into the drying chamber 3 for drying. A placement seat 207 is rotatably connected to the bottom sealing plate 206. A material cylinder 208 is snapped onto the top of the placement seat 207. A connecting shaft 209 is fixedly connected to the bottom end of the placement seat 207. A driven disc 210 is fixedly connected to the bottom end of the connecting shaft 209. An active disc 213 is provided at the bottom of the driven disc 210. A rotary motor 214 is fixedly connected to the bottom end of the active disc 213. The rotary motor 214 is fixedly installed inside the machine body 1, and the output shaft end of the rotary motor 214 is fixedly connected to the active disc 213, so that the rotary motor 214 can... The drive disk 213 is able to rotate. Multiple first magnets 212 are fixedly connected to the drive disk 213, and multiple second magnets 211 are fixedly connected to the driven disk 210. The multiple first magnets 212 and multiple second magnets 211 are each set of two sets of magnets, and the magnetic poles of each set of magnets are set to opposite magnetic poles from top to bottom. The two sets of magnets are alternately set so that the first magnets 212 and the second magnets 211 can attract each other and achieve magnetic coupling, thereby enabling the drive disk 213 to drive the driven disk 210 to rotate.
[0024] Please see Figure 1 and Figure 4The switching mechanism 4 includes a main sealing door 401, a main handle 402 fixedly connected to the main sealing door 401, one end of the main sealing door 401 being rotatably connected to the body 1, and two sub-sealing doors 403 being rotatably connected inside the main sealing door 401. All of the above sealing doors are magnetically fixed, and each of the two sub-sealing doors 403 is fixedly connected to a sub-handle 404. Both the main sealing door 401 and the sub-sealing doors 403 are provided with sealing strips 405, which can increase the sealing performance. The freezing chamber 5 and the drying chamber 3 can be opened separately through the two sub-sealing doors 403, while the entire assembly can be opened using the main sealing door 401, effectively improving the flexibility and convenience of use.
[0025] During operation, sodium heparin is placed inside the material cylinder 208. After being frozen by liquid nitrogen inside the freezing chamber 5, the feeding motor 204 drives the feeding screw 202 to rotate. The rotation of the feeding screw 202 causes the top sealing plate 203 to move. The movement of the top sealing plate 203 causes the connecting rod 205 to move. The movement of the connecting rod 205 causes the bottom sealing plate 206 to move, thus sending the material cylinder 208 into the drying chamber 3. The microwave generator 6 performs drying. At the same time, the active disk 213 and the driven disk 210 are magnetically coupled using the first magnet 212 and the second magnet 211. The rotary motor 214 drives the active disk 213 to rotate. The rotation of the active disk 213 causes the driven disk 210 to rotate. The rotation of the driven disk 210 causes the placement seat 207 to rotate. The rotation of the placement seat 207 causes the material cylinder 208 to rotate, so that the product comes into uniform contact with the microwaves emitted by the microwave generator 6, thereby effectively improving the drying effect.
[0026] Furthermore, any content not described in detail in this specification is existing technology known to those skilled in the art.
Claims
1. A heparin sodium freeze-drying apparatus comprising a body (1), characterized in that: The machine body (1) is provided with a freezing chamber (5) and a drying chamber (3) inside. A feeding mechanism (2) is provided between the freezing chamber (5) and the drying chamber (3). A microwave generator (6) is installed inside the drying chamber (3). A switching mechanism (4) is provided on the front side of the machine body (1). The feeding mechanism (2) includes a guide rod (201) and a feeding screw (202). A feeding motor (204) is fixedly connected to the top end of the feeding screw (202). A top sealing plate (203) is threadedly connected to the feeding screw (202). The guide rod (201) is slidably connected to the top sealing plate (203). A plurality of connecting rods (205) are fixedly connected to the bottom end of the top sealing plate (203). A bottom sealing plate (206) is fixedly connected to the bottom end of the plurality of connecting rods (205). A placement device is rotatably connected to the bottom sealing plate (206). The placement seat (207) has a material cylinder (208) snapped onto its top. A connecting shaft (209) is fixedly connected to the bottom of the placement seat (207). A driven disk (210) is fixedly connected to the bottom of the connecting shaft (209). An active disk (213) is provided at the bottom of the driven disk (210). A rotary motor (214) is fixedly connected to the bottom of the active disk (213). A plurality of first magnets (212) are fixedly connected to the active disk (213). A plurality of second magnets (211) are fixedly connected to the driven disk (210).
2. The heparin sodium freeze-drying apparatus according to claim 1, characterized by: The guide rod (201) is fixedly installed inside the freezing chamber (5), and the feeding screw (202) is rotatably connected to the inner wall of the freezing chamber (5).
3. The heparin sodium freeze-drying apparatus according to claim 1, characterized by: A passage is provided between the freezing chamber (5) and the drying chamber (3), and the area of the passage is smaller than the area of the top sealing plate (203) and the bottom sealing plate (206).
4. The heparin sodium freeze-drying equipment according to claim 1, characterized in that: The top sealing plate (203) and the bottom sealing plate (206) are respectively disposed inside the freezing chamber (5) and the drying chamber (3), and the drying chamber (3) is disposed at the bottom of the freezing chamber (5).
5. The heparin sodium freeze-drying equipment according to claim 1, characterized in that: The rotary motor (214) is fixedly installed inside the machine body (1), and the output shaft end of the rotary motor (214) is fixedly connected to the drive disk (213).
6. The heparin sodium freeze-drying apparatus according to claim 1, characterized in that: The plurality of first magnets (212) and the plurality of second magnets (211) are each configured as two sets of magnets, and the magnetic poles of each set of magnets are set to opposite magnetic poles from top to bottom, and the two sets of magnets are arranged alternately.
7. The heparin sodium freeze-drying apparatus according to claim 1, characterized in that: The switching mechanism (4) includes a main sealing door (401), on which a main handle (402) is fixedly connected, and one end of the main sealing door (401) is rotatably connected to the body (1).
8. The heparin sodium freeze-drying apparatus according to claim 7, characterized in that: The main sealing door (401) is internally connected to two sub-sealing doors (403), each of which is fixedly connected to a handle (404). Both the main sealing door (401) and the sub-sealing doors (403) are provided with sealing strips (405).