Piston assembly, detection consumable, and detection apparatus

Abstract

This utility model belongs to the field of medical device technology, specifically relating to a piston assembly, a detection consumable, and a detection device. The piston assembly is used in a detection consumable, which includes a sample tube for containing a first reagent, a reaction tube for containing a second reagent, and a diaphragm located between the reaction tube and the sample tube to isolate them. The piston assembly is housed within the sample tube and includes: a piston with a puncture head at its bottom for puncturing the diaphragm; and a puncture column located at the end of the piston away from the diaphragm, extending axially along the sample tube. The first reagent in the sample tube can pass through the perforated portion into the puncture column. The puncture column contains an adsorption element for adsorbing impurities in the first reagent. The puncture column drives the piston downward, allowing the adsorbed first reagent to enter the reaction tube for reaction. Using the above-mentioned piston assembly enables efficient and portable detection of the first reagent.

Description

Technical Field

[0001] This utility model belongs to the field of medical device technology, specifically relating to a piston assembly, testing consumables, and testing equipment. Background Technology

[0002] In the testing of samples (such as sputum, urine, and blood), the sample needs to be pretreated in a test tube with a processing solution. The pretreated mixture is then transferred to another container using a pipette before subsequent testing procedures such as nucleic acid extraction or PCR amplification can be performed. Specifically, current molecular detection experiments in in vitro diagnostics require collecting a pharyngeal or nasal swab from the patient, placing it in a sample tube for storage, and then using an external machine to open the tube, aspirate the sample, pretreat it, transfer it, extract nucleic acid, and perform PCR amplification.

[0003] The above method requires three steps: pretreatment, aspiration, and output to achieve detection. In particular, it involves multiple consumables, and the sample transfer and detection processes are complicated and inefficient. Utility Model Content

[0004] The purpose of this invention is to provide a piston assembly, detection consumables, and detection equipment to achieve more portable and efficient detection of the first reagent.

[0005] To achieve the above objectives, this utility model provides a piston assembly for use in a detection consumable. The detection consumable includes a sample tube for containing a first reagent, a reaction tube for containing a second reagent, and a diaphragm located between the reaction tube and the sample tube for isolating the two tubes. The piston assembly is housed within the sample tube and includes:

[0006] The piston has a piercing head at its bottom for piercing the diaphragm.

[0007] The puncture column is located at the end of the piston away from the diaphragm. The puncture column extends along the axial direction of the sample tube. The side wall of the puncture column is provided with a perforated part. The first reagent in the sample tube can pass through the perforated part and enter the puncture column. The puncture column is provided with an adsorbent for adsorbing impurities of the first reagent. The puncture column is used to drive the piston to move downward so that the first reagent after adsorption treatment can enter the reaction tube for reaction.

[0008] In some embodiments, the puncture column has multiple adsorption pore groups on its wall for the entry of the first reagent from the sample tube. The multiple adsorption pore groups are evenly spaced along the circumference of the puncture column, and each adsorption pore group includes multiple adsorption pores evenly spaced along the axial direction of the puncture column.

[0009] In some embodiments, the adsorption element has a spherical structure, and the diameter of each adsorption pore is smaller than the diameter of the adsorption element.

[0010] In some embodiments, the piston assembly further includes: a baffle, which is sleeved on the outer periphery of the puncture column and slides in contact with the inner peripheral wall of the sample tube; a plurality of adsorption pore groups are located between the baffle and the piston; and at least one clearance notch is provided on the baffle.

[0011] In some embodiments, the piston assembly also includes a plurality of reinforcing plates connected between the bottom of the baffle and the outer peripheral wall of the puncture post.

[0012] In some embodiments, the top of the sample tube is provided with a sealing element, which abuts against the top of the puncture column. The sealing element is used to apply an axial force to the puncture column and drive the puncture column downward.

[0013] The second aspect of this utility model provides a testing consumable, which includes: a reaction tube for containing a second reagent; a sample tube for containing a first reagent; a diaphragm located between the reaction tube and the sample tube and used to isolate the reaction tube and the sample tube; and the piston assembly described above.

[0014] In some embodiments, a quantitative section extending in the axial direction is provided inside the sample tube. The quantitative section is located at one end of the sample tube near the diaphragm. A piston is movably inserted into the quantitative section and slidably connected to the inner wall of the quantitative section. The piston is used to separate a fixed amount of first reagent located below the piston from the first reagent located at the top of the piston.

[0015] In some embodiments, the sidewall of the piercing head is provided with multiple flow channels for guiding the first reagent.

[0016] The third aspect of this utility model provides a testing device, including the aforementioned testing consumables.

[0017] The piston assembly in the above-described technical solution can be used in a detection consumable, which includes a sample tube, a reaction tube, and a diaphragm tube. The sample tube contains a first reagent, the reaction tube contains a second reagent, and the diaphragm is located between the sample tube and the reaction tube, isolating them. The piston assembly is housed within the sample tube and includes a piston and a puncture column. The piston has a puncture head at its bottom for piercing the diaphragm, and the puncture column is located at the end of the piston away from the diaphragm and extends along the axial direction of the sample tube. The sidewall of the puncture column has a perforated portion. The first reagent in the sample tube can smoothly enter the puncture column, which contains an adsorbent that effectively adsorbs and removes impurities (such as unwanted proteins and lipids) from the first reagent, ensuring its purity. The puncture column not only serves as a carrier for the adsorbent but also plays a crucial role in driving the piston downwards. This design allows the adsorbed first reagent to accurately enter the reaction tube and react with the second reagent, significantly improving the portability and efficiency of the detection.

[0018] Other features and advantages of this invention will be described in detail in the following detailed description section. Attached Figure Description

[0019] The accompanying drawings are provided to further illustrate the embodiments of the present invention and form part of the specification. They are used together with the following detailed description to explain the embodiments of the present invention, but do not constitute a limitation thereof. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without any inventive effort. In the drawings:

[0020] Figure 1 This is a cross-sectional schematic diagram of the testing consumables provided according to an embodiment of the present utility model;

[0021] Figure 2 This is a schematic diagram of the structure of the testing consumables provided according to an embodiment of the present utility model;

[0022] Figure 3 This is a cross-sectional schematic diagram of a piston assembly provided according to an embodiment of the present utility model;

[0023] Figure 4 This is a schematic diagram of the piston assembly provided according to an embodiment of the present utility model;

[0024] Figure 5 This is a schematic diagram of the sealing component structure provided according to an embodiment of the present utility model;

[0025] Figure 6 This is a cross-sectional schematic diagram of a sample tube provided according to an embodiment of the present utility model;

[0026] Figure 7 This is a cross-sectional schematic diagram of the diaphragm provided according to an embodiment of the present invention.

[0027] Explanation of reference numerals in the attached figures

[0028] 100 sample tubes

[0029] 110 Quantitative Section

[0030] 120 Annular mounting groove

[0031] 200 reaction tube

[0032] 210 Ring-shaped connector

[0033] 300 Piston Assembly

[0034] 310 Piston

[0035] 311 Pierced the head

[0036] 320 puncture column

[0037] 321 Adsorption pores

[0038] 330 baffle

[0039] 331 Avoidance Gap

[0040] 340 Reinforced Plate

[0041] 400 sealing components

[0042] 600 diaphragm

[0043] 610 Set-up Department

[0044] 611 Annular Seal

[0045] 620 Diaphragm Section

[0046] 630 Guiding Section

[0047] 631 Guide Surface Detailed Implementation

[0048] The specific embodiments of this utility model will be described in detail below with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are for illustration and explanation only and are not intended to limit the scope of this utility model.

[0049] The piston assembly 300, testing consumables, and testing equipment according to this utility model are described below with reference to the accompanying drawings. Figure 1 The image shown is a cross-sectional schematic diagram of the testing consumables provided according to an embodiment of the present utility model; as shown... Figure 2 The diagram shown is a structural schematic of the testing consumables provided according to an embodiment of the present invention; as shown... Figure 3 The image shown is a cross-sectional schematic diagram of a piston assembly 300 provided according to an embodiment of the present invention; as shown... Figure 4 The diagram shown is a structural schematic of the piston assembly 300 provided according to an embodiment of the present invention.

[0050] This utility model provides a piston assembly 300 for use in a detection consumable. The detection consumable includes a sample tube 100 for containing a first reagent, a reaction tube 200 for containing a second reagent, and a diaphragm 600 located between the reaction tube 200 and the sample tube 100 for isolating the reaction tube 200 and the sample tube 100. The piston assembly 300 is housed within the sample tube 100 and includes:

[0051] Piston 310, with a piercing head 311 at the bottom for piercing diaphragm 600;

[0052] The puncture column 320 is located at the end of the piston 310 away from the diaphragm 600. The puncture column 320 extends along the axial direction of the sample tube 100. The side wall of the puncture column 320 is provided with a hollow part (not shown in the figure). The first reagent in the sample tube 100 can pass through the hollow part and enter the puncture column 320. The puncture column 320 is provided with an adsorption element (not shown in the figure) for adsorbing impurities of the first reagent. The puncture column 320 is used to drive the piston 310 to move downward so that the first reagent after adsorption treatment can enter the reaction tube 200 for reaction.

[0053] In existing technologies, when detecting the first reagent, it is usually necessary to pre-treat the first reagent to remove impurities, and then transfer the first reagent to the reaction tube 200 for reaction to obtain the reaction result. The above steps require multiple different consumables, are complicated, and have low detection efficiency.

[0054] This invention provides a piston assembly 300 for a testing consumable, which includes a sample tube 100, a reaction tube 200, and a diaphragm 600. The sample tube 100 stores a first reagent, and the reaction tube 200 stores a second reagent. The diaphragm 600 is located between the sample tube 100 and the reaction tube 200, serving to isolate them. The piston assembly 300 is installed inside the sample tube 100 and includes a piston 310 and a puncture post 320. A puncture head 311 is disposed at the bottom of the piston 310. The puncture head 311 punctures the diaphragm 600 at an appropriate time, allowing the first reagent to contact and react with the second reagent in the reaction tube 200, enabling more convenient pipetting of the first reagent. The puncture post 320 is located at the end of the piston 310 opposite to the diaphragm 600 and extends along the axial direction of the sample tube 100. The sidewall of the puncture post 320 has a perforated portion. The perforated design not only allows the first reagent in sample tube 100 to smoothly enter its interior, but also incorporates an adsorption element. The main function of the adsorption element is to adsorb and remove impurities from the first reagent, such as proteins and lipids that do not need to be detected, thereby ensuring the purity of the first reagent, achieving a pretreatment effect, and improving the accuracy of the detection. The first reagent can be selected as a processing solution, and the second reagent can be selected as a reaction reagent.

[0055] The puncture column 320 not only serves as a carrier for the adsorbent, but also plays another important role: driving the piston 310 downwards. As the puncture column 320 moves downwards, it pushes the piston 310 downwards until the puncture head 311 punctures the diaphragm 600. This design allows the first reagent, after adsorption treatment, to accurately enter the reaction tube 200 and react with the second reagent therein, thereby greatly improving the efficiency and accuracy of the detection.

[0056] In one embodiment, such as Figure 3 As shown, the puncture column 320 has multiple adsorption pore groups on its wall for the entry of the first reagent from the sample tube 100. These adsorption pore groups are evenly spaced along the circumference of the puncture column 320, and each group includes multiple adsorption holes 321 evenly spaced along the axial direction of the puncture column 320. This design allows the first reagent to enter the puncture column 320 more uniformly, increasing the contact opportunity between the first reagent and the adsorption element, thereby improving the impurity removal efficiency. Furthermore, the evenly distributed adsorption pore groups also help maintain pressure balance within the puncture column 320, avoiding excessive resistance during the entry of the first reagent and ensuring smooth flow of the first reagent.

[0057] In one embodiment, such as Figure 3 As shown, the adsorbent has a spherical structure, and the diameter of each adsorption pore 321 is smaller than the diameter of the adsorbent. The spherical structure of the adsorbent is simple to manufacture and occupies little space, allowing it to roll effectively within the puncture column 320, increasing the contact area with the first reagent and improving the adsorption efficiency of impurities. Simultaneously, because the diameter of each adsorption pore 321 is smaller than the diameter of the adsorbent, this ensures that the adsorbent will not fall or move randomly within the puncture column 320, maintaining its stability within the column and further guaranteeing the impurity removal effect.

[0058] In one embodiment, such as Figure 3 As shown, the piston assembly 300 further includes a baffle 330, which is sleeved on the outer periphery of the puncture column 320 and slides in contact with the inner peripheral wall of the sample tube 100. Multiple adsorption pore groups are located between the baffle 330 and the piston 310. The baffle 330 has at least one clearance notch 331. The baffle 330 can slide in contact with the inner wall of the sample tube 100. When the puncture column 320 moves up and down, the baffle 330 can guide and limit the movement of the puncture column 320, ensuring that the movement direction of the puncture column 320 is axial, preventing the puncture head 311 from deviating from the diaphragm 600. Furthermore, the clearance notch 331 on the baffle 330 facilitates airflow up and down, allowing the puncture column 320 to move more smoothly. Additionally, the clearance notch 331 allows the sampling swab to pass through the clearance notch 331 from top to bottom of the sample tube 100 and come into contact with the first reagent. Multiple adsorption holes 321 are located between the baffle 330 and the piston 310, allowing the first reagent to pass more smoothly through the adsorption hole group into the puncture column 320, ensuring the smooth flow of the first reagent. The presence of the baffle 330 also enhances the structural stability of the piston assembly 300, making its movement within the sample tube 100 more stable and reliable.

[0059] In one embodiment, such as Figure 3As shown, the piston assembly 300 also includes multiple reinforcing plates 340 connected between the bottom of the baffle 330 and the outer peripheral wall of the puncture post 320. The multiple reinforcing plates 340 increase the connection strength between the baffle 330 and the puncture post 320, preventing the baffle 330 from deforming or being damaged during the movement of the piston assembly 300, further improving the structural stability and durability of the piston assembly 300. The design of the reinforcing plates 340 also takes into account weight reduction, minimizing their impact on the overall weight of the piston assembly 300 and ensuring that the piston assembly 300 can respond flexibly and quickly to operations.

[0060] In one embodiment, such as Figure 1 As shown, the sample tube 100 has a sealing element 400 at its top end, which abuts against the top end of the puncture column 320. The sealing element 400 applies an axial force to the puncture column 320 and drives it downward. This sealing element 400 seals the top space of the sample tube 100, preventing leakage of the first reagent during movement. After the sealing element 400 applies an axial force to the puncture column 320, it drives the puncture column 320 downward, allowing the puncture head 311 to puncture the diaphragm 600. The first reagent in the sample tube 100 then passes through the diaphragm 600 and reacts with the second reagent in the reaction tube 200 for sample detection.

[0061] In another specific embodiment, such as Figure 5 The diagram shown is a schematic representation of the sealing member 400 provided according to an embodiment of the present invention. The bottom end of the sealing member 400 can abut against the puncture column 320, and the top end of the sealing member 400 can protrude from the top end of the sample tube 100. An operator can apply an axial force to the sealing member 400 to cause the sealing member 400 to drive the puncture column 320 downward.

[0062] In one embodiment, such as Figure 1 and Figure 2 As shown, a detection consumable is provided, comprising: a reaction tube 200, a sample tube 100, a diaphragm 600, and the aforementioned piston assembly 300. The reaction tube 200 is used to contain a second reagent, the sample tube 100 is used to contain a first reagent, and the diaphragm 600 is located between the reaction tube 200 and the sample tube 100 to isolate them. Using this detection consumable allows for more portable and efficient detection of the first reagent, and the three steps of pretreatment, aspiration, and output can be completed using only one detection consumable, reducing consumable costs and space requirements.

[0063] In one embodiment, such as Figure 1As shown, a quantitative section 110 extending axially is provided inside the sample tube 100. The quantitative section 110 is located at the end of the sample tube 100 near the diaphragm 600. A piston 310 is movably inserted into the quantitative section 110 and slidably connected to the inner wall of the quantitative section 110. The piston 310 is used to separate a fixed amount of first reagent located below the piston 310 from the first reagent located at the top of the piston 310. The quantitative section 110 can guide the movement direction of the piston 310, ensuring that the piston 310 moves stably along the axial direction inside the sample tube 100 and preventing the piston 310 from tilting or getting stuck during movement. The sliding connection between the quantitative section 110 and the piston 310 also prevents the first reagent from leaking out from the gap between the piston 310 and the quantitative section 110 during the movement of the piston 310, ensuring the purity of the first reagent and the accuracy of the detection. Furthermore, the design of the quantitative section 110 helps improve the smoothness of the piston assembly 300's movement, allowing the piston 310 to puncture the diaphragm 600 more smoothly, reducing resistance and energy consumption during the puncture process, and further improving the efficiency and accuracy of the detection. In addition, the design of the quantitative section 110 enables the piston 310 to quantitatively separate the first reagent, ensuring that the volume of the first reagent entering the reaction tube 200 each time is the same, thus improving detection accuracy.

[0064] In one embodiment, such as Figure 6 The diagram shown is a cross-sectional view of a sample tube 100 according to an embodiment of the present invention. Above the quantitative portion 110 of the sample tube 100, a plurality of axially extending guide strips (not shown) are provided. These guide strips further guide the piston 310 axially. Before the piston 310 engages with the quantitative portion 110, the first reagent inside the quantitative portion 110 and the first reagent outside the quantitative portion 110 are in a mutually permeable state. When the piston 310 moves along the guide strips to the quantitative portion 110, the piston 310 quantitatively separates the first reagent within the quantitative portion 110, achieving the effect of quantitative detection of the first reagent.

[0065] In one embodiment, such as Figure 1 As shown, the sidewall of the piercing head 311 has multiple flow channels (not shown in the figure) for guiding the first reagent. If the cross-section of the piercing head 311 is a convex polygon or a circle, it will be difficult for the first reagent to flow into the gap between the diaphragm 600 and the piercing head 311 after the piercing head 311 pierces the diaphragm 600. Based on this technical problem, this invention provides multiple flow channels for guiding the first reagent on the sidewall of the piercing head 311. After the piercing head 311 pierces the diaphragm 600, the first reagent can flow along the flow channels into the reaction tube 200 to react. Using the above-mentioned piercing head 311, the first reagent can be introduced into the reaction tube 200 more smoothly, avoiding the problem of low detection efficiency caused by poor flow of the first reagent.

[0066] In one specific embodiment, there are two guide grooves, which are respectively arranged opposite to each other on both sides of the piercing head 311. Both guide grooves are arc-shaped and concave inward toward the axis of the piercing head 311.

[0067] In one embodiment, such as Figure 7 The diagram shows a cross-sectional view of the diaphragm 600 provided according to an embodiment of the present invention. The outer periphery of the reaction tube 200 is engaged with the inner peripheral wall of the sample tube 100. The diaphragm 600 includes a sleeve portion 610, a diaphragm portion 620, and a guide portion 630 connected in sequence. The sleeve portion 610 is sleeved on the outer periphery of the reaction tube 200 and located between the outer peripheral wall of the reaction tube 200 and the inner peripheral wall of the sample tube 100. The diaphragm portion 620 is located at the top of the reaction tube 200 and is used to close the top opening of the reaction tube 200. The guide portion 630 is located above the reaction tube 200 and its outer periphery is fitted with the inner peripheral wall of the sample tube 100. The guide portion 630 has a guide channel for the piercing head 311 to move axially. The top opening of the reaction tube 200 is inserted into the inner periphery of the sample tube 100, and the outer periphery of the reaction tube 200 is engaged with the inner peripheral wall of the sample tube 100. The diaphragm 600 includes a sleeve portion 610, a diaphragm portion 620, and a guide portion 630 connected in sequence. The sleeve portion 610 is sleeved on the outer periphery of the reaction tube 200 and located between the outer peripheral wall of the reaction tube 200 and the inner peripheral wall of the sample tube 100 to achieve a stable connection between the diaphragm 600 and the reaction tube 200 and the sample tube 100. The diaphragm portion 620 is located at the top of the reaction tube 200 and fits tightly against the top opening of the reaction tube 200, effectively isolating the liquid in the reaction tube 200 and the sample tube 100, preventing unreacted first reagent from entering the reaction tube 200, and ensuring the accuracy of the detection. The guide portion 630 is located above the reaction tube 200, and its outer periphery fits tightly against the inner peripheral wall of the sample tube 100, forming a guide channel for the piercing head 311 to move axially, guiding the piercing head 311 to accurately pierce the diaphragm portion 620, allowing the first reagent to flow smoothly into the reaction tube 200. This design not only improves the stability of the diaphragm 600 assembly, but also ensures the efficiency and accuracy of the reaction between the first and second reagents.

[0068] In one embodiment, the diaphragm 600 is a sheet-like structure, and the diaphragm 600 is fixedly installed at the top opening of the reaction tube 200 and can seal the top opening of the reaction tube 200.

[0069] In one embodiment, the diaphragm 600 has a sheet-like structure and is fixedly installed below the metering section 110 and abuts against the top of the reaction tube 200.

[0070] In one embodiment, such as Figure 1As shown, the reaction tube 200 is a conical tube. This design helps to distribute the first reagent evenly within the reaction tube 200, improves the reaction efficiency between the first and second reagents, and thus enhances the sensitivity and accuracy of the detection.

[0071] In one embodiment, such as Figure 1 As shown, the outer periphery of the reaction tube 200 is provided with an annular insertion portion 210, and the inner peripheral wall of the sample tube 100 is provided with an annular mounting groove 120. When assembling the testing consumables, the diaphragm 600 is first fitted onto the top opening of the reaction tube 200, and then the sample tube 100 is fitted onto the diaphragm 600. The annular mounting groove 120 of the sample tube 100 and the annular insertion portion 210 of the reaction tube 200 cooperate with each other, so that the sample tube 100 and the reaction tube 200 can be stably connected together.

[0072] In one embodiment, such as Figure 7 As shown, an annular guide surface 631 is formed on the inner periphery of the top of the guide portion 630, and the annular guide surface 631 is an inclined surface. The inclined surface can further guide the piercing head 311, so that the piercing head 311 can move precisely along the axial direction of the sample tube 100 and pierce the diaphragm portion 620 downward.

[0073] In one embodiment, such as Figure 7 As shown, the inner peripheral wall of the sleeve 610 has an annular sealing ring 611, which seals against the outer peripheral wall of the reaction tube 200. The annular sealing ring 611 effectively prevents the first reagent from leaking through the gap between the diaphragm 600 and the reaction tube 200, ensuring that the first reagent flows completely into the reaction tube 200 to react with the second reagent, further improving the accuracy and reliability of the detection. Furthermore, the design of the annular sealing ring 611 enhances the connection stability between the diaphragm 600 and the reaction tube 200, avoiding problems such as diaphragm 600 detachment or displacement due to pressure from the first reagent or improper operation.

[0074] In one specific embodiment, when the first reagent needs to be tested, the first reagent is stored in the sample tube 100, and the second reagent is stored in the reaction tube 200. The diaphragm 600 is installed at the bottom of the sample tube 100, and the sample tube 100 is placed over the reaction tube 200. The piston assembly 300 is inserted, allowing the first reagent to flow from the adsorption hole 321 into the puncture column 320. The adsorption element in the puncture column 320 can pre-treat the proteins and lipids in the first reagent to improve its purity. After a period of pre-treatment, the adsorption is confirmed to be complete. The puncture column 320 is moved downward by the sealing element 400, and then the piston 310 moves downward along the quantitative section 110, separating the quantitative first reagent from the first reagent above the piston 310. The piston 310 continues to move downward, causing the puncture head 311 to puncture the diaphragm 600, allowing the first reagent to flow into the reaction tube 200 along the guide groove of the puncture head 311. The above steps are simple to operate and effectively pre-treat, aspirate, and dispense the first reagent, completing the entire detection process. This integrated design not only simplifies the operation but also reduces the number of testing consumables used, lowering costs. Furthermore, since all steps are completed within a single testing consumable, it reduces the potential contamination of the first reagent during transfer, improving detection accuracy.

[0075] In practical operation, the user simply adds the first reagent to the sample tube 100 and then assembles the detection consumables. Next, after adsorption pretreatment, the piston assembly 300 is driven by the sealing component 400 or other driving device, causing it to move downwards along the axial direction of the sample tube 100. During this movement, the piercing head 311 of the piston assembly 300 pierces the diaphragm 600, allowing the first reagent to flow into the reaction tube 200 and react with the second reagent.

[0076] Furthermore, this testing consumable offers high flexibility and adaptability. For example, by adjusting the size, number, and distribution of the adsorption pores 321, it can accommodate first reagents of different properties and concentrations. Simultaneously, by changing the type and material of the adsorption element, it can be optimized for different testing needs. Moreover, this testing consumable can be integrated with other testing instruments or systems to achieve automated, high-throughput testing, further improving testing efficiency and accuracy.

[0077] In the description of this utility model, it should be understood that the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this utility model, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0078] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection, an electrical connection, or a connection that allows communication between them; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise explicitly limited. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0079] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0080] Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention. Those skilled in the art can make changes, modifications, substitutions and variations to the above embodiments within the scope of the present invention.

Claims

1. A piston assembly characterized by, The piston assembly (300) is used in a detection consumable, the detection consumable including a sample tube (100) for containing a first reagent, a reaction tube (200) for containing a second reagent, and a diaphragm (600) located between the reaction tube (200) and the sample tube (100) for isolating the reaction tube (200) and the sample tube (100). The piston assembly (300) is housed within the sample tube (100), and the piston assembly (300) includes: A piston (310) is provided with a piercing head (311) at the bottom of the piston (310) for piercing the diaphragm (600). A puncture column (320) is disposed at one end of the piston (310) away from the diaphragm (600). The puncture column (320) extends along the axial direction of the sample tube (100). The side wall of the puncture column (320) is provided with a hollow part. The first reagent in the sample tube (100) can pass through the hollow part and enter the puncture column (320). The puncture column (320) is provided with an adsorbent for adsorbing impurities of the first reagent. The puncture column (320) is used to drive the piston (310) to move downward so that the first reagent after adsorption treatment enters the reaction tube (200) for reaction.

2. The piston assembly of claim 1, wherein The puncture column (320) has multiple adsorption pore groups on its wall for the first reagent in the sample tube (100) to enter. The multiple adsorption pore groups are evenly spaced along the circumference of the puncture column (320), and each adsorption pore group includes multiple adsorption pores (321) evenly spaced along the axial direction of the puncture column (320).

3. The piston assembly of claim 2, wherein, The adsorption element has a spherical structure, and the diameter of each adsorption pore (321) is smaller than the diameter of the adsorption element.

4. The piston assembly of claim 2, wherein, The piston assembly (300) also includes: A baffle (330) is fitted around the outer periphery of the puncture column (320) and slides in contact with the inner peripheral wall of the sample tube (100). Multiple adsorption pore groups are located between the baffle (330) and the piston (310). At least one clearance notch (331) is provided on the baffle (330).

5. The piston assembly of claim 4, wherein, The piston assembly (300) also includes a plurality of reinforcing plates (340) connected between the bottom of the baffle (330) and the outer peripheral wall of the puncture post (320).

6. The piston assembly (300) according to any one of claims 1 to 5, characterized in that The sample tube (100) is provided with a sealing member (400) at the top end. The sealing member (400) abuts against the top end of the puncture column (320). The sealing member (400) is used to apply an axial force to the puncture column (320) and drive the puncture column (320) to move downward.

7. A detection consumable, characterized in that, include: The reaction tube (200) is used to contain the second reagent; Sample tube (100) for containing the first reagent; A diaphragm (600) is located between the reaction tube (200) and the sample tube (100) and is used to isolate the reaction tube (200) and the sample tube (100). The piston assembly (300) according to any one of claims 1 to 6.

8. The test consumable of claim 7, wherein, The sample tube (100) is provided with a quantitative part (110) extending along the axial direction. The quantitative part (110) is located at one end of the sample tube (100) near the diaphragm (600). The piston (310) is movably inserted into the quantitative part (110) and slidably connected to the inner wall of the quantitative part (110). The piston (310) is used to separate a fixed amount of the first reagent located below the piston (310) from the first reagent located at the top of the piston (310).

9. The test consumable of claim 7, wherein, The sidewall of the piercing head (311) is provided with multiple flow channels for guiding the first reagent.

10. A detection device, characterized by The testing consumables include any one of claims 7 to 9.

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