A 96-well plate anti-cross contamination cover plate

Abstract

The utility model relates to the technical field of orifice plate cover plate, especially to a kind of orifice plate cross-contamination prevention cover plate, including placing groove board, the both sides of placing groove board surface are equipped with sliding slot, sliding baffle is slidably arranged on the upper end of sliding slot, the surface of sliding baffle is equipped with sample addition groove, one end of placing groove board is rotatably equipped with winding roller, protective film is wound on the surface of winding roller, one end of protective film is fixed with sliding baffle, by setting protective film and sliding baffle, the effective isolation of 96 orifice plate already added sample area and not added sample area is realized, protective film can cover the part of 96 orifice plate not added sample, prevent liquid splash and aerosol transmission to cause pollution to this part area;Sliding baffle then shields the orifice plate part already added sample, avoid the interference of subsequent operation to the area already added sample, to greatly reduce the risk of cross-contamination, improve the accuracy and reliability of experimental result.

Description

Technical Field

[0001] This utility model relates to the field of perforated plate cover technology, specifically a 96-hole plate cover to prevent cross-contamination. Background Technology

[0002] In many fields such as biomedical research, clinical testing, and drug screening, the 96-well plate is an extremely common experimental instrument. Its high throughput allows it to simultaneously hold 96 samples for various experimental operations, greatly improving experimental efficiency. For example, in cell culture experiments, different concentrations of drugs can be added to each well of a 96-well plate to observe the cells' response; in enzyme-linked immunosorbent assays (ELISA), the 96-well plate can be used to simultaneously detect specific antigens or antibodies in multiple samples.

[0003] During sample loading, liquid can easily splash out of the target well due to factors such as improper operation of the pipette, excessively fast loading speed, or the viscosity of the sample itself. This splashed liquid may fall into adjacent wells, leading to cross-contamination between different samples.

[0004] Researchers may make mistakes during operation, such as inserting the pipette into the wrong hole or failing to clean residual liquid from the pipette after application. These human factors can lead to cross-contamination between samples, especially during prolonged and intensive experiments, where the probability of such errors may increase. Therefore, a 96-hole plate anti-cross-contamination cover is needed to improve the above problems. Utility Model Content

[0005] The purpose of this invention is to provide a 96-hole plate anti-cross-contamination cover to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides the following technical solution: A perforated plate anti-cross-contamination cover includes a placement groove plate, with sliding grooves on both sides of the surface of the placement groove plate, a sliding baffle plate slidably provided at the upper end of the sliding groove, a sample loading groove provided on the surface of the sliding baffle plate, a take-up roller rotatably provided at one end of the placement groove plate, a protective film wrapped around the surface of the take-up roller, and one end of the protective film being fixed to the sliding baffle plate.

[0007] As a preferred embodiment of this utility model, the sliding baffle is generally concave, and the protruding parts at the lower ends of both sides of the sliding baffle are slidably disposed inside the sliding groove.

[0008] As a preferred embodiment of this utility model, the placement slot is provided in the center of the placement slot plate with a placement slot for adapting the perforated plate, and the placement slot and the sample loading slot are arranged vertically and vertically respectively.

[0009] As a preferred embodiment of this utility model, a motor is fixedly provided at one end of the placement trough plate, and the motor is connected to the winding roller for transmission.

[0010] In a preferred embodiment of this invention, both the protective film and the sliding baffle are transparent.

[0011] Compared with the prior art, the beneficial effects of this utility model are: 1. This utility model achieves effective isolation between the sample-added and unsample-added areas of a 96-well plate by setting a protective film and a sliding baffle. The protective film can cover the unsample-added part of the 96-well plate, preventing liquid splashing and aerosol propagation from contaminating this part of the plate; the sliding baffle blocks the sample-added part of the plate, avoiding interference from subsequent operations in the sample-added area, thereby greatly reducing the risk of cross-contamination and improving the accuracy and reliability of experimental results.

[0012] 2. Both the protective film and the sliding baffle of this utility model are transparent, allowing operators to clearly observe the sample addition and experimental status of each well in the well plate without opening the cover. This not only facilitates experimental operations but also reduces the chance of contamination that may be introduced due to frequent opening of the cover, further enhancing the anti-contamination effect. Attached Figure Description

[0013] Figure 1 This is a schematic diagram of the overall three-dimensional structure of this utility model; Figure 2 This is a three-dimensional structural diagram of the placement slot plate of this utility model; Figure 3 This is a schematic diagram of the overall transparent structure of this utility model; Figure 4 This is a top view schematic diagram of the overall structure of this utility model.

[0014] In the diagram: 1. Placing trough; 2. Slide chute; 3. Motor; 4. Rewinding roller; 5. Protective film; 6. Sample loading trough; 7. Sliding baffle. Detailed Implementation

[0015] The technical solutions of the present utility model will be clearly and completely described below with reference to the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present utility model without creative effort are within the protection scope of the present utility model.

[0016] To facilitate understanding of this utility model, a more comprehensive description of it will be provided below with reference to relevant embodiments. Several embodiments of this utility model are given. However, this utility model can be implemented in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided so that the disclosure of this utility model will be more thorough and complete.

[0017] It should be noted that when a component is said to be "fixed to" another component, it can be directly on the other component or there may be an intervening component. When a component is said to be "connected to" another component, it can be directly connected to the other component or there may be an intervening component. The terms "vertical," "horizontal," "left," "right," and similar expressions used in this document are for illustrative purposes only.

[0018] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0019] Please see Figure 1-4 This utility model provides a technical solution: a 96-well plate anti-cross-contamination cover, including a placement groove plate 1, with sliding grooves 2 on both sides of the surface of the placement groove plate 1, a sliding baffle 7 slidably mounted on the upper end of the sliding grooves 2, a sample loading groove 6 on the surface of the sliding baffle 7, and a take-up roller 4 rotatably mounted on one end of the placement groove plate 1. A protective film 5 is wound around the surface of the take-up roller 4, and one end of the protective film 5 is fixed to the sliding baffle 7. Before using the 96-well plate anti-cross-contamination cover, the 96-well plate needs to be placed in the placement groove in the center of the placement groove plate 1. When the sample loading operation begins... When motor 3 starts, its power is transmitted to take-up roller 4 through the transmission device, causing take-up roller 4 to start rotating. Since the protective film 5 is wrapped around the surface of take-up roller 4 and one end is fixed to sliding baffle 7, the rotation of take-up roller 4 will drive the protective film 5 to be gradually wound up. As the protective film 5 is wound up, the sliding baffle 7 fixedly connected to it is subjected to tension. The protrusions at the lower ends of both sides of the sliding baffle 7 slide inside the slide groove 2, thereby driving the sliding baffle 7 to move along the direction of the slide groove 2. This movement is continuous and synchronized with the winding process of the protective film 5.

[0020] As an example of this utility model, the sliding baffle 7 is generally concave, and the protruding parts at the lower ends of both sides of the sliding baffle 7 are slidably disposed inside the sliding groove 2.

[0021] As an example of this utility model, the center of the placement slot plate 1 is provided with a placement slot adapted to the 96-well plate, and the placement slot and the sample loading slot 6 are arranged vertically in correspondence.

[0022] As an example of this utility model, a motor 3 is fixedly provided at one end of the placement trough plate 1. The motor 3 is connected to the winding roller 4 for transmission. During the movement of the sliding baffle 7, the protective film 5 always covers the unsampled well plate portion. Since the protective film 5 is transparent, the operator can clearly see the well positions of the 96-well plate through the protective film 5. However, the protective film 5 plays an isolation role, preventing liquid splashing or aerosol contamination of the unsampled well plate area during the sample addition process. The sliding baffle 7, on the other hand, blocks the well plate portion that has been sampled, avoiding interference from subsequent operations in the sampled area and preventing cross-contamination. The sample addition operation is carried out through the sample addition groove 6 on the sliding baffle 7. The position of the sample addition groove 6 corresponds vertically to the well positions of the 96-well plate in the placement trough, ensuring that the sample addition operation can be accurately carried out at the designated well positions.

[0023] As an example of this utility model, both the protective film 5 and the sliding baffle 7 are transparent.

[0024] Working principle: Before using the 96-hole plate anti-cross-contamination cover, the 96-hole plate needs to be placed in the placement slot in the center of the placement slot plate 1. When the sample addition operation begins, the motor 3 starts, and its power is transmitted to the winding roller 4 through the transmission device, causing the winding roller 4 to start rotating. Since the protective film 5 is wrapped around the surface of the winding roller 4 and one end is fixed to the sliding baffle 7, the rotation of the winding roller 4 will drive the protective film 5 to be gradually wound up. As the protective film 5 is wound up, the sliding baffle 7 fixedly connected to it is subjected to tension. The protrusions at the lower ends of both sides of the sliding baffle 7 slide inside the slide groove 2, thereby driving the sliding baffle 7 to move along the direction of the slide groove 2. This movement is continuous and synchronized with the winding process of the protective film 5. During the movement of the sliding baffle 7, the protective film 5 always covers the unsampled well plate area. Since the protective film 5 is transparent, the operator can clearly see the well positions of the 96-well plate through the protective film 5. However, the protective film 5 also serves as an isolation layer to prevent liquid splashing or aerosol contamination of the unsampled well plate area during the sample addition process. Meanwhile, the sliding baffle 7 blocks the sampled well plate area to prevent the sampled area from being interfered with by subsequent operations and to prevent cross-contamination. The sample addition operation is carried out through the sample addition slot 6 on the sliding baffle 7. The position of the sample addition slot 6 corresponds vertically to the well positions of the 96-well plate placed in the slot, ensuring that the sample addition operation can be accurately performed at the designated well positions.

[0025] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A 96-well plate anti-cross contamination cover plate comprising a placing slot plate (1), characterized in that: The placement trough plate (1) has sliding grooves (2) on both sides of its surface. A sliding baffle (7) is slidably provided at the upper end of the sliding groove (2). A sample loading groove (6) is provided on the surface of the sliding baffle (7). A take-up roller (4) is rotatably provided at one end of the placement trough plate (1). A protective film (5) is wrapped around the surface of the take-up roller (4). One end of the protective film (5) is fixed to the sliding baffle (7).

2. The cross contamination prevention cover plate for a 96 well plate of claim 1, wherein: The sliding baffle (7) is concave in shape, and the protruding parts at the lower ends of both sides of the sliding baffle (7) are slidably disposed inside the sliding groove (2).

3. A cross contamination prevention cover plate for a 96 well plate according to claim 2, wherein: The placement slot (1) is provided with a placement slot adapted to a 96-well plate at its center, and the placement slot and the sample loading slot (6) are arranged vertically and vertically respectively.

4. The cross contamination prevention cover plate for a 96 well plate of claim 3, wherein: One end of the placement trough plate (1) is fixedly equipped with a motor (3), and the motor (3) is connected to the winding roller (4) for transmission.

5. A cross contamination prevention cover plate for a 96 well plate according to claim 4, wherein: Both the protective film (5) and the sliding baffle (7) are transparent.

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