Liquid-based cell preparation, staining, sealing and reading integrated machine reading module

Abstract

The reading module of the liquid-based cell preparation, dyeing, sealing and reading integrated machine is characterized in that: the reading module is integrated with the slide cache box, the slide rotating table mechanism, the bar code scanner, the slide clamping jaw mechanism, the slide scanning mechanism and the computer, so that the automatic scanning and reading operation of the sample slide can be realized, the whole process does not need manual intervention, the necessity of manual operation in the reading process is replaced, and the reading efficiency and stability are greatly improved.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, and in particular to the slide reading module of a liquid-based cell slide preparation, staining, mounting and reading integrated machine. Background Technology

[0002] Exfoliative cytology is a diagnostic method that utilizes normally shed cells from human tissue. Liquid-based cytology, a part of exfoliative cytology, involves placing cytological specimens that are difficult to process using traditional methods into an intermediate liquid to remove interfering components such as blood and mucus, thereby improving diagnostic efficiency. Compared to traditional cervical smears (Pap smears), liquid-based cytology significantly improves specimen quality and the detection rate of abnormal cervical cells.

[0003] Liquid-based cytology testing typically involves steps such as slide preparation, staining, packaging, and slide reading. Traditional slide reading is usually done manually, requiring long hours of work and resulting in inconsistent quality and a lengthy process due to human error. Utility Model Content

[0004] In view of the above-mentioned problems in the existing technology, the slide reading module of the liquid-based cell preparation, staining, mounting and reading machine provided by this utility model solves the problems existing in the background technology.

[0005] To achieve the above-mentioned objectives, the technical solution adopted by this utility model is as follows:

[0006] The slide reading module of the liquid-based cell preparation, staining, mounting, and reading integrated machine includes a base plate and a computer. The base plate is equipped with a slide buffer box, a slide rotation stage mechanism, a slide gripper mechanism, and a slide scanning mechanism. The slide scanning mechanism is equipped with a barcode scanner.

[0007] The glass slide rotating stage mechanism is used to receive the prepared glass slides from the previous process of the integrated machine;

[0008] The barcode scanner is used to scan the barcode on the surface of the slide located on the slide rotation stage mechanism and transmit the obtained information to the computer.

[0009] The slide clamping mechanism is used to clamp the slide located on the slide rotating stage mechanism to the slide scanning mechanism. After the slide scanning mechanism completes the scanning, the slide located on the slide scanning mechanism is clamped to the slide rotating stage mechanism. The slide rotating stage mechanism sends the scanned slide to the slide holder used to place the slide in the next process of the integrated machine.

[0010] The slide buffer box is used for temporary storage of slides when online scanning fails during the scanning phase;

[0011] The slide scanning mechanism is used to scan the slides fed by the slide gripper mechanism and transmit the scanned information to the computer;

[0012] The computer receives and processes information transmitted from the barcode scanner and slide scanning mechanism to obtain the final image information and slide reading results.

[0013] In one embodiment, the slide rotation stage mechanism includes a first slide rail disposed on the base plate in a left-right direction, a first slider slidably disposed on the first slide rail, a first baffle disposed on the base plate at the left and right ends of the first slide rail, a first lead screw rotatably disposed between the two first baffles, a first motor disposed on the right side wall of the first baffle on the right side, the main shaft of the first motor being drivenly connected to the right end of the first lead screw, the first lead screw passing through the first slider and being screwed to the first slider, a second motor base plate disposed on the first slider, a second motor disposed on the left end of the second motor base plate, the main shaft of the second motor being vertically disposed, and a rotating plate disposed at its top end, slide placement grooves being disposed at the left and right ends of the upper surface of the rotating plate, and a first notch being disposed at the front end of the slide placement groove on the right side and the rear end of the slide placement groove on the left side.

[0014] In one embodiment, a second notch is provided on the left side wall of the slide placement groove on the left and the right side wall of the slide placement groove on the right. An "L"-shaped slide clamping block is rotatably arranged inside the two second notches by a rotating shaft and a torsion spring. The upper end of the slide clamping block is located inside the second notch and the lower end is located below the rotating plate. Electromagnets are provided on the left and right side walls of the second motor. A vertically movable push rod is arranged inside the upper end of the electromagnet. The top end of the push rod is located below the lower end of the slide clamping block.

[0015] In one embodiment, the slide gripper mechanism includes a second slide rail disposed on the base plate in a left-right direction, a second slider slidably disposed on the second slide rail, second baffles respectively disposed on the base plate at the left and right ends of the second slide rail, a second lead screw rotatably disposed between the two second baffles, a third motor disposed on the right side wall of the second baffle on the right side, the main shaft of the third motor being drivenly connected to the right end of the second lead screw, the second lead screw passing through the second slider and screwed to the second slider.

[0016] The second slider is provided with a third slide rail base plate, and a third slide rail side plate is longitudinally arranged on the third slide rail base plate. A third slide rail is longitudinally arranged on the left side wall of the third slide rail side plate. A third slider is slidably arranged on the third slide rail. A third baffle is respectively provided on the third slide rail side plate at the upper and lower ends of the third slide rail. A third lead screw is rotatably arranged between the two third baffles. A fourth motor is arranged on the top of the upper third baffle. The main shaft of the fourth motor is drivenly connected to the upper end of the third lead screw. The third lead screw passes through the third slider and is screwed to the third slider.

[0017] A fourth slide rail base plate is provided on the left side wall of the third slider. A fourth slide rail is provided on the fourth slide rail base plate along the front-back direction. A fourth slider is slidably provided on the fourth slide rail. A fourth baffle is provided on the fourth slide rail base plate at the front and rear ends of the fourth slide rail. A fourth lead screw is rotatably provided between the two fourth baffles. A fifth motor is provided on the rear side wall of the fourth baffle at the rear end. The main shaft of the fifth motor is connected to the rear end of the fourth lead screw. The fourth lead screw passes through the fourth slider and is screwed to the fourth slider.

[0018] An electric gripper mounting plate is provided below the fourth slider. An electric gripper is provided on the rear side wall of the electric gripper mounting plate, and the gripping end of the electric gripper faces rearward.

[0019] In one embodiment, the second slide rail is located in front of the first slide rail, and the two are arranged parallel to each other.

[0020] In one embodiment, the slide scanning mechanism includes a fifth slide rail base plate located on a base plate behind the first slide rail. Two fifth slide rails are arranged side by side on the fifth slide rail base plate, and the two fifth slide rails are parallel to the first slide rail. Fifth sliders are slidably mounted on the two fifth slide rails. A sixth slide rail base plate is located above the two fifth sliders. A first transmission plate is mounted on the lower side wall of the sixth slide rail base plate. Fifth baffles are mounted on the fifth slide rail base plates located on the left and right sides of the first transmission plate. A fifth lead screw is rotatably mounted between the two fifth baffles. A sixth motor is mounted on the right side wall of the fifth baffle on the right side. The main shaft of the sixth motor is connected to the right end of the fifth lead screw. The fifth lead screw passes through the first transmission plate and is screwed to the first transmission plate.

[0021] Two sixth slide rails are arranged side by side on the bottom plate of the sixth slide rail. The two sixth slide rails are parallel to the fourth slide rail. Sixth sliders are slidably arranged on the two sixth slide rails. Platform plates are provided at the front ends of the two sixth sliders. A second transmission plate is provided between the two sixth sliders. Sixth baffles are provided on the bottom plate of the sixth slide rails located on the front and rear sides of the second transmission plate. A sixth lead screw is rotatably arranged between the two sixth baffles. A seventh motor is provided on the rear side wall of the rear end of the sixth baffle. The main shaft of the seventh motor is connected to the rear end of the sixth lead screw. The sixth lead screw passes through the second transmission plate and is screwed to the second transmission plate.

[0022] The platform plate has a slide groove at its front end, a condenser lens at its lower end, a condenser lens light source at its lower end, a rotating objective lens at its upper end, and a lens at its upper end.

[0023] In one embodiment, a condenser lens base is provided on a base plate located below the front end of the platform plate, and a "Z"-shaped condenser lens support plate is provided on the condenser lens base. The condenser lens light source is located on the rear end of the condenser lens support plate.

[0024] In one embodiment, lens support plates are respectively provided on the left and right sides of the fifth slide rail base plate, and lens base plates are provided on the two lens support plates. The lens is disposed on the lens base plate, and a first through hole is provided on the lens base plate at a position corresponding to the light-incident end of the lens. The barcode scanner is disposed on the left side of the front end of the lens base plate, and the slide buffer box is disposed to the left of the barcode scanner. A second through hole is provided on the lens base plate located to the left of the lens. A seventh slide rail base plate is disposed on the lens base plate. The lower end extends downward through the second through hole. A seventh slide rail is longitudinally arranged on the right side wall of the seventh slide rail base plate. A seventh slider is slidably arranged on the seventh slide rail. Seventh baffles are respectively arranged on the seventh slide rail base plate at the upper and lower ends of the seventh slider. A seventh lead screw is rotatably arranged between the two seventh baffles. An eighth motor is arranged on the top of the upper seventh baffle. The main shaft of the eighth motor is connected to the upper end of the seventh lead screw. An objective lens support plate is arranged on the right side wall of the seventh slider. The rotating objective lens is mounted on the objective lens support plate.

[0025] The rear side wall of the seventh slider is provided with an objective lens conversion motor support plate, the objective lens conversion motor support plate is provided with a ninth motor, the main shaft of the ninth motor is provided with a pulley, and the rotating part of the objective lens is connected to the pulley by a belt for transmission.

[0026] In one embodiment, the objective lens includes an objective lens disk, a light guide tube is embedded at the top of the objective lens disk, an objective lens support plate is clamped to the outside of the upper end of the light guide tube, a rotating ring is rotatably arranged on the outside of the objective lens disk, one end of the belt is fitted onto the outside of the rotating ring, an objective lens mounting plate is arranged below the rotating ring, and a plurality of objective lenses are embedded in a circular array along the center of the lower surface of the objective lens mounting plate. The light emitted by the condenser light source passes upward through the condenser, the glass slide in the slide groove, one of the objective lenses, the light guide tube, the first through hole, and then enters the light entrance end of the lens.

[0027] Compared with existing technologies, the slide reading module of the liquid-based cell preparation, staining, mounting and reading machine provided by this utility model can automatically scan and read sample slides by integrating a slide buffer box, a slide rotating stage mechanism, a barcode scanner, a slide gripper mechanism, a slide scanning mechanism and a computer. The whole process does not require manual intervention, replacing the need for manual operation in the slide reading process, and greatly improving the efficiency and stability of slide reading. Attached Figure Description

[0028] Figure 1 This is a partial three-dimensional structural diagram of the present invention;

[0029] Figure 2 This is a schematic diagram of a partial left-side view of the present invention;

[0030] Figure 3 This is a partial structural diagram of the right side of this utility model;

[0031] Figure 4 This is a schematic diagram of the second partial three-dimensional structure of the present invention;

[0032] Figure 5 This is a schematic diagram of the third partial three-dimensional structure of the present invention;

[0033] Figure 6 This is a schematic diagram of the fourth partial three-dimensional structure of the present invention. Detailed Implementation

[0034] In the description of this utility model, it should be understood that the terms "center", "longitudinal", "lateral", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "axial", "radial", etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0035] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly specified.

[0036] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0037] In this utility model, unless otherwise explicitly specified and limited, "above" or "below" the second feature can mean that the first feature is in direct contact with the second feature, or that the first feature is in indirect contact with the second feature through an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0038] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0039] like Figure 1-6 As shown, for ease of description, the orientation references of "up", "down", "left", "right", "front" and "rear" in this utility model are attached. Figure 1 The directions shown are for reference only;

[0040] The slide reading module of the liquid-based cell preparation, staining, mounting, and reading machine includes a base plate 1 and a computer. The base plate 1 is equipped with a slide buffer box 2, a slide rotation stage mechanism, a slide gripper mechanism, and a slide scanning mechanism. The slide scanning mechanism is equipped with a barcode scanner 3.

[0041] The slide rotation mechanism is used to receive the prepared slides from the previous process of the integrated machine;

[0042] Barcode scanner 3 is used to scan the barcode on the surface of the slide located on the slide rotation stage mechanism and transmit the obtained information to the computer.

[0043] The slide clamping mechanism is used to clamp and send the slides located on the slide rotating stage mechanism to the slide scanning mechanism. After the slide scanning mechanism completes the scanning, the slides located on the slide scanning mechanism are clamped and sent to the slide rotating stage mechanism. The slide rotating stage mechanism sends the scanned slides to the slide holder used to place the slides in the next process of the integrated machine.

[0044] Slide buffer box 2 is used to temporarily store slides when online scanning fails during the scanning stage, and subsequent error correction can be performed manually.

[0045] The slide scanning mechanism is used to scan the slides fed by the slide gripper mechanism and transmit the scanned information to the computer;

[0046] The computer receives and processes information transmitted from the barcode scanner 3 and the slide scanning mechanism to obtain the final image information and slide reading results.

[0047] In this embodiment, the slide rotation stage mechanism includes a first slide rail 4 arranged on a base plate 1 in the left-right direction, a first slider 5 slidably arranged on the first slide rail 4, a first baffle 6 respectively arranged on the base plate at the left and right ends of the first slide rail 4, a first lead screw 7 rotatably arranged between the two first baffles 6, a first motor 8 arranged on the right side wall of the first baffle 6 on the right side, the main shaft of the first motor 8 is connected to the right end of the first lead screw 7, the first lead screw 7 passes through the first slider 5 and is screwed to the first slider 5, so that by controlling the first motor 8 to rotate forward and reverse, the first slider 5 can be driven to move back and forth left and right;

[0048] A second motor base plate 9 is provided on the first slider 5. A second motor 10 is provided on the left end of the second motor base plate 9. The main shaft of the second motor 10 is vertically arranged, and a rotating plate 11 is provided at its top. Slide placement grooves 12 are provided at the left and right ends of the upper surface of the rotating plate 11. A first notch 13 is provided at the front end of the right slide placement groove 12 and the rear end of the left slide placement groove 12. In this way, the rotating plate 11 can be driven to rotate by controlling the second motor 10 to rotate in both directions. The first notch 13 is provided on the two slide placement grooves 12 to facilitate the electric gripper to clamp the slides.

[0049] Furthermore, second notches are respectively provided on the left side wall of the slide placement groove 12 on the left and the right side wall of the slide placement groove 12 on the right. Inside the two second notches, L-shaped slide clamping blocks 13 are rotatably mounted via a rotating shaft and a torsion spring. The upper end of the slide clamping block 13 is located inside the second notch, and the lower end is located below the rotating plate 11. Electromagnets 14 are respectively provided on the left and right side walls of the second motor 10. A vertically movable push rod 15 is longitudinally mounted inside the upper end of the electromagnet 14. The top end of the push rod 15 is located below the lower end of the slide clamping block 13. When the electromagnet 14 is driven... When the push rod 15 moves downward, the top end of the push rod 15 separates from the lower end of the slide clamping block 13. At this time, the upper end of the slide clamping block 13 rotates inward under the drive of the torsion spring, thereby pressing the slide inside the slide placement groove 12 into the slide placement groove 12. Similarly, when the electromagnet 14 drives the push rod 15 to move upward, the top end of the push rod 15 contacts the lower end of the slide clamping block 13, thereby driving the slide clamping block 13 to rotate, so that the upper end of the slide clamping block 13 separates from the slide inside the slide placement groove 12, thereby releasing the pressure on the slide.

[0050] In this embodiment, the slide gripper mechanism includes a second slide rail 16 arranged on the base plate 1 in the left-right direction, a second slider 17 slidably arranged on the second slide rail 16, a second baffle 18 respectively arranged on the base plate 1 at the left and right ends of the second slide rail 17, a second lead screw 19 rotatably arranged between the two second baffles 18, a third motor 20 arranged on the right side wall of the second baffle 18 on the right side, the main shaft of the third motor 20 is connected to the right end of the second lead screw 19, the second lead screw 19 passes through the second slider 17 and is screwed to the second slider 17. Similarly, by controlling the third motor 20 to rotate forward and reverse, the second slider 17 can be driven to move back and forth left and right.

[0051] The second slider 17 is provided with a third slide rail base plate 21, the third slide rail base plate 21 is provided with a third slide rail side plate 22 in a longitudinal direction, the third slide rail 23 is provided in a longitudinal direction on the left side wall of the third slide rail side plate 22, the third slider 24 is provided in a sliding direction on the third slide rail 23, the third slide rail side plate 22 located at the upper and lower ends of the third slide rail 23 is provided with a third baffle 25 respectively, the third baffle 25 is provided with a third lead screw 26 rotating between the two third baffles 25, the top of the upper third baffle 25 is provided with a fourth motor 27, the main shaft of the fourth motor 27 is connected to the upper end of the third lead screw 26, the third lead screw 26 passes through the third slider 24 and is screwed to the third slider 24. Similarly, by controlling the fourth motor 27 to rotate forward and reverse, the third slider 24 can be driven to move up and down.

[0052] A fourth slide rail base plate 28 is provided on the left side wall of the third slider 24. A fourth slide rail 29 is provided on the fourth slide rail base plate 28 along the front-back direction. A fourth slider 30 is slidably provided on the fourth slide rail 29. A fourth baffle 31 is provided on the fourth slide rail base plate 28 at the front and rear ends of the fourth slide rail 29. A fourth lead screw 32 is rotatably provided between the two fourth baffles 31. A fifth motor 33 is provided on the rear side wall of the fourth baffle 31 at the rear end. The main shaft of the fifth motor 33 is connected to the rear end of the fourth lead screw 32. The fourth lead screw 32 passes through the fourth slider 30 and is screwed to the fourth slider 30. Similarly, by controlling the fifth motor 33 to rotate forward and reverse, the fourth slider 30 can be driven to move back and forth.

[0053] An electric gripper mounting plate 34 is provided below the fourth slider 30. An electric gripper 35 is provided on the rear side wall of the electric gripper mounting plate 34, and the gripping end of the electric gripper 35 faces the rear. Therefore, by controlling the forward and reverse rotation of the third, fourth and fifth motors, the electric gripper 35 can move in the forward, backward, left and right and up and down directions. This enables the electric gripper 35 to clamp and send the glass slide on the rotating plate 11 to the glass slide scanning mechanism. After the glass slide scanning mechanism completes the scanning, the glass slide on the glass slide scanning mechanism is clamped and sent to the glass slide rotating table mechanism. The glass slide rotating table mechanism sends the scanned glass slide to the glass slide rack used to place the glass slide in the previous process of the integrated machine.

[0054] In this embodiment, the second slide rail 17 is located in front of the first slide rail 4, and the two are arranged parallel to each other, so that the electric gripper 35 on the second slide rail 17 and the rotating plate 11 on the first slide rail 4 can work together better.

[0055] In this embodiment, the slide scanning mechanism includes a fifth slide rail base plate 36 located on a base plate 1 behind the first slide rail 4. Two fifth slide rails 37 are arranged side by side on the fifth slide rail base plate 36, and the two fifth slide rails 37 are parallel to the first slide rail 4. Fifth sliders 38 are slidably arranged on the two fifth slide rails 37 respectively. A sixth slide rail base plate 39 is arranged above the two fifth sliders 38. A first transmission plate 40 is arranged on the lower side wall of the sixth slide rail base plate 39. Fifth baffles 41 are arranged on the fifth slide rail base plates 36 located on the left and right sides of the first transmission plate 40 respectively. A fifth lead screw 42 is rotatably arranged between the two fifth baffles 41. A sixth motor 43 is arranged on the right side wall of the fifth baffle 41 on the right side. The main shaft of the sixth motor 43 is connected to the right end of the fifth lead screw 42. The fifth lead screw 42 passes through the first transmission plate 40 and is screwed to the first transmission plate 40. By controlling the sixth motor 43 to rotate forward and reverse, the first transmission plate 40 can be driven to move back and forth left and right.

[0056] Two sixth slide rails 44 are arranged side by side on the sixth slide rail base plate 39. The two sixth slide rails 44 are parallel to the fourth slide rail 29. Sixth sliders 45 are slidably arranged on the two sixth slide rails 44 respectively. Platform plates 46 are arranged at the front end of the two sixth sliders 45. A second transmission plate 47 is arranged between the two sixth sliders 45. Sixth baffles 48 are arranged on the sixth slide rail base plate 39 on the front and rear sides of the second transmission plate 47 respectively. A sixth lead screw 49 is rotatably arranged between the two sixth baffles 48. A seventh motor 50 is arranged on the rear side wall of the sixth baffle 49 at the rear end. The main shaft of the seventh motor 50 is connected to the rear end of the sixth lead screw 49. The sixth lead screw 49 passes through the second transmission plate 47 and is screwed to the second transmission plate 47. By controlling the seventh motor 50 to rotate forward and reverse, the second transmission plate 47 can be driven to move back and forth.

[0057] The platform plate 46 has a slide groove 51 at its front end, a condenser lens 52 at its lower end, a condenser lens light source 53 at its lower end, a rotating objective lens at its upper end, and a lens 54 at its upper end. Therefore, by controlling the forward and reverse rotation of the sixth and seventh motors, the platform plate can be moved forward and backward and left and right, thereby facilitating the adjustment of the position of the slide inside the slide groove 51 for slide scanning operations.

[0058] In this embodiment, a condenser lens base 55 is provided on the base plate 1 located below the front end of the platform plate 46, and a "Z"-shaped condenser lens support plate 56 is provided on the condenser lens base 55. The condenser lens light source 53 is located on the rear end of the condenser lens support plate 56.

[0059] In this embodiment, lens support plates 57 are respectively provided on the left and right sides of the fifth slide rail base plate 36. Lens base plates 58 are provided on the two lens support plates 57. Lens 54 is mounted on the lens base plate 58. A first through hole is provided on the lens base plate 58 at a position corresponding to the light-incident end of lens 54. Barcode scanner 3 is mounted on the left side of the front end of lens base plate 58 via a connecting plate. Slide buffer box 2 is located to the left of barcode scanner 3. A second through hole is provided on the lens base plate to the left of lens 54. A seventh slide rail base plate 59 is provided on lens base plate 58. The lower end of the seventh slide rail base plate 59 extends downward through the second through hole. A seventh slide rail is longitudinally arranged on the right side wall of the base plate 59. A seventh slider 61 is slidably mounted on the seventh slide rail. Seventh baffles 62 are respectively mounted on the base plate 59 at the upper and lower ends of the seventh slide rail. A seventh lead screw 63 is rotatably mounted between the two seventh baffles 62. An eighth motor 64 is mounted on the top of the upper seventh baffle 62. The main shaft of the eighth motor 64 is connected to the upper end of the seventh lead screw 63. An objective lens support plate 65 is mounted on the right side wall of the seventh slider 61. A rotating objective lens is mounted on the objective lens support plate 65. The objective lens can be moved up and down by controlling the eighth motor 64 to rotate forward and backward.

[0060] The seventh slider 61 has an objective lens conversion motor support plate 66 on its rear side wall. The objective lens conversion motor support plate 66 has a ninth motor 67. The main shaft of the ninth motor 67 has a pulley 68. The rotating part of the objective lens is connected to the pulley 68 by a belt 69.

[0061] Furthermore, the objective lens includes an objective lens disk 70, with a light guide tube 71 embedded at the top of the objective lens disk 70. An objective lens support plate 66 is clamped to the outside of the upper end of the light guide tube 71. A rotating ring 72 is rotatably mounted on the outside of the objective lens disk 70. One end of a belt 69 is fitted onto the outside of the rotating ring 72. An objective lens mounting plate is provided below the rotating ring 72. Multiple objective lenses 73 are embedded in a circular array along the center of the lower surface of the objective lens mounting plate. Switching between the multiple objective lenses 73 can be achieved by controlling the rotation of the ninth motor 67.

[0062] The light emitted from the condenser light source 53 travels upward through the condenser lens 52, the glass slide in the slide groove 51, one of the objective lenses 73, the light guide tube 71, the first through hole, and then enters the light entrance end of the lens 54.

[0063] The working process of the slide reading module of the liquid-based cell preparation, staining, mounting, and reading machine provided by this utility model is as follows: First, the rotating plate 11 is driven to move to the far left by the first motor 8. Then, the gripper from the previous process places the sample slide prepared in the previous process into the slide placement slot 12 on the left side of the rotating plate 11. Then, the second motor 10 drives the rotating plate 11 to rotate, so that the slide placement slot 12 containing the sample slide moves to the right side. Then, driven by the first motor, it moves to below the barcode scanner 3. The barcode scanner 3 then scans the barcode information on the surface of the slide. The scanning process begins, and the scanned information is transmitted to the computer. After the barcode scan is complete, the first motor 8 continues to drive the rotating plate 11 to the far right. At this point, the electric gripper 35 is driven by the forward and reverse rotation of the third, fourth, and fifth motors. The gripper 35, in conjunction with its own gripper portion, clamps the slide on the rotating plate 11 into the slide slot 51. Then, the sixth and seventh motors are used to adjust the position of the slide, the eighth motor 63 adjusts the vertical position of the objective lens, and the ninth motor 67 drives the rotating ring 72 to rotate to select the appropriate objective lens 73 for the slide scanning operation. After completion, the scanned information is transmitted to the computer. The computer obtains the patient's personal information by receiving barcode scanner 3 and scans the sample slide by receiving scan information from lens 54. The computer processes and interprets the image using relevant software and, combined with the patient's personal information corresponding to the slide information, generates a specific test report for the patient. Simultaneously, after the slide scan is completed, the electric gripper 35 is driven by controlling the forward and reverse rotation of the third, fourth, and fifth motors. The gripper on the electric gripper 35, in conjunction with its own gripping part, holds the slide located in the slide slot 51. The slide is clamped into the slide placement slot 12 on the right side of the rotating plate 11. Then, the first motor 8 drives the rotating plate 11 to move to the leftmost position, and the second motor 10 drives the rotating plate 11 to rotate, so that the slide placement slot 12 containing the scanned slides moves to the left side. Then, the gripper in the previous process of the integrated machine will place the scanned slides onto the slide holder for storing the scanned slides. The above operation is repeated to realize the automatic scanning and reading of sample slides. The whole process does not require manual intervention, which replaces the need for manual operation in the reading process and greatly improves the efficiency and stability of reading.

[0064] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0065] The embodiments described above are merely illustrative of several implementations of this utility model, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of this utility model patent. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this utility model, and these all fall within the protection scope of this utility model. Therefore, the protection scope of this utility model patent should be determined by the appended claims.

Claims

1. The slide reading module of a liquid-based cell preparation, staining, mounting, and reading integrated machine, characterized in that: The system includes a base plate and a computer. The base plate is equipped with a slide buffer box, a slide rotation stage mechanism, a slide gripper mechanism, and a slide scanning mechanism. The slide scanning mechanism is equipped with a barcode scanner. The glass slide rotating stage mechanism is used to receive the prepared glass slides from the previous process of the integrated machine; The barcode scanner is used to scan the barcode on the surface of the slide located on the slide rotation stage mechanism and transmit the obtained information to the computer. The slide clamping mechanism is used to clamp the slide located on the slide rotating stage mechanism to the slide scanning mechanism. After the slide scanning mechanism completes the scanning, the slide located on the slide scanning mechanism is clamped to the slide rotating stage mechanism. The slide rotating stage mechanism sends the scanned slide to the slide holder used to place the slide in the next process of the integrated machine. The slide buffer box is used for temporary storage of slides when online scanning fails during the scanning phase; The slide scanning mechanism is used to scan the slides fed by the slide gripper mechanism and transmit the scanned information to the computer; The computer receives and processes information transmitted from the barcode scanner and slide scanning mechanism to obtain the final image information and slide reading results.

2. The slide reading module of the liquid-based cell preparation, staining, mounting, and reading integrated machine according to claim 1, characterized in that, The slide rotation stage mechanism includes a first slide rail arranged in a left-right direction on the base plate, a first slider slidably mounted on the first slide rail, first baffles respectively located on the base plate at the left and right ends of the first slide rail, a first lead screw rotatably mounted between the two first baffles, a first motor mounted on the right side wall of the first baffle on the right side, the main shaft of the first motor being drivenly connected to the right end of the first lead screw, the first lead screw passing through the first slider and screwed to the first slider, a second motor base plate mounted on the first slider, a second motor mounted on the left end of the second motor base plate, the main shaft of the second motor being vertically mounted, and a rotating plate mounted on its top end, slide placement grooves respectively located at the left and right ends of the upper surface of the rotating plate, and first notches respectively located at the front end of the slide placement groove on the right side and the rear end of the slide placement groove on the left side.

3. The slide reading module of the liquid-based cell preparation, staining, mounting, and reading integrated machine according to claim 2, characterized in that, The left side wall of the slide placement slot on the left and the right side wall of the slide placement slot on the right are respectively provided with second notches. Inside the two second notches, "L"-shaped slide clamping blocks are respectively rotatably arranged by a rotating shaft and a torsion spring. The upper end of the slide clamping block is located inside the second notch, and the lower end is located below the rotating plate. Electromagnets are respectively provided on the left and right side walls of the second motor. The upper end of the electromagnet is provided with a vertically movable push rod, and the top end of the push rod is located below the lower end of the slide clamping block.

4. The slide reading module of the liquid-based cell preparation, staining, mounting, and reading integrated machine according to claim 2, characterized in that, The slide gripper mechanism includes a second slide rail disposed on the base plate in a left-right direction, a second slider slidably disposed on the second slide rail, second baffles respectively disposed on the base plate at the left and right ends of the second slide rail, a second lead screw rotatably disposed between the two second baffles, a third motor disposed on the right side wall of the second baffle on the right side, the main shaft of the third motor being drivenly connected to the right end of the second lead screw, the second lead screw passing through the second slider and being screwed to the second slider. The second slider is provided with a third slide rail base plate, and a third slide rail side plate is longitudinally arranged on the third slide rail base plate. A third slide rail is longitudinally arranged on the left side wall of the third slide rail side plate. A third slider is slidably arranged on the third slide rail. A third baffle is respectively provided on the third slide rail side plate at the upper and lower ends of the third slide rail. A third lead screw is rotatably arranged between the two third baffles. A fourth motor is arranged on the top of the upper third baffle. The main shaft of the fourth motor is drivenly connected to the upper end of the third lead screw. The third lead screw passes through the third slider and is screwed to the third slider. A fourth slide rail base plate is provided on the left side wall of the third slider. A fourth slide rail is provided on the fourth slide rail base plate along the front-back direction. A fourth slider is slidably provided on the fourth slide rail. A fourth baffle is provided on the fourth slide rail base plate at the front and rear ends of the fourth slide rail. A fourth lead screw is rotatably provided between the two fourth baffles. A fifth motor is provided on the rear side wall of the fourth baffle at the rear end. The main shaft of the fifth motor is connected to the rear end of the fourth lead screw. The fourth lead screw passes through the fourth slider and is screwed to the fourth slider. An electric gripper mounting plate is provided below the fourth slider. An electric gripper is provided on the rear side wall of the electric gripper mounting plate, and the gripping end of the electric gripper faces rearward.

5. The slide reading module of the liquid-based cell preparation, staining, mounting, and reading integrated machine according to claim 4, characterized in that, The second slide rail is located in front of the first slide rail, and the two are arranged parallel to each other.

6. The slide reading module of the liquid-based cell preparation, staining, mounting, and reading integrated machine according to claim 5, characterized in that, The slide scanning mechanism includes a fifth slide rail base plate located on a base plate behind the first slide rail. Two fifth slide rails are arranged side by side on the fifth slide rail base plate, and the two fifth slide rails are parallel to the first slide rail. Fifth sliders are slidably mounted on the two fifth slide rails. A sixth slide rail base plate is located above the two fifth sliders. A first transmission plate is located on the lower side wall of the sixth slide rail base plate. Fifth baffles are located on the fifth slide rail base plates on the left and right sides of the first transmission plate. A fifth lead screw is rotatably mounted between the two fifth baffles. A sixth motor is located on the right side wall of the fifth baffle on the right side. The main shaft of the sixth motor is connected to the right end of the fifth lead screw. The fifth lead screw passes through the first transmission plate and is screwed to the first transmission plate. Two sixth slide rails are arranged side by side on the bottom plate of the sixth slide rail. The two sixth slide rails are parallel to the fourth slide rail. Sixth sliders are slidably arranged on the two sixth slide rails. Platform plates are provided at the front ends of the two sixth sliders. A second transmission plate is provided between the two sixth sliders. Sixth baffles are provided on the bottom plate of the sixth slide rails located on the front and rear sides of the second transmission plate. A sixth lead screw is rotatably arranged between the two sixth baffles. A seventh motor is provided on the rear side wall of the rear end of the sixth baffle. The main shaft of the seventh motor is connected to the rear end of the sixth lead screw. The sixth lead screw passes through the second transmission plate and is screwed to the second transmission plate. The platform plate has a slide groove at its front end, a condenser lens at its lower end, a condenser lens light source at its lower end, a rotating objective lens at its upper end, and a lens at its upper end.

7. The slide reading module of the liquid-based cell preparation, staining, mounting, and reading integrated machine according to claim 6, characterized in that, A condenser lens base is provided on the base plate located below the front end of the platform plate. A "Z"-shaped condenser lens support plate is provided on the condenser lens base. The condenser lens light source is located on the rear end of the condenser lens support plate.

8. The slide reading module of the liquid-based cell preparation, staining, mounting, and reading integrated machine according to claim 7, characterized in that, Lens support plates are respectively arranged on the left and right sides of the fifth slide rail base plate. Lens base plates are arranged on the two lens support plates, and the lens is mounted on the lens base plate. A first through hole is provided on the lens base plate at a position corresponding to the light-incident end of the lens. The barcode scanner is located on the left side of the front end of the lens base plate, and the slide buffer box is located to the left of the barcode scanner. A second through hole is provided on the lens base plate located to the left of the lens. A seventh slide rail base plate is arranged on the lens base plate, with its lower end penetrating the second through hole. A seventh slide rail is longitudinally arranged on the right side wall of the seventh slide rail base plate, and a seventh slider is slidably arranged on the seventh slide rail. Seventh baffles are respectively arranged on the seventh slide rail base plates at the upper and lower ends of the seventh slider. A seventh lead screw is rotatably arranged between the two seventh baffles. An eighth motor is arranged on the top of the upper seventh baffle, and the main shaft of the eighth motor is connected to the upper end of the seventh lead screw. An objective lens support plate is arranged on the right side wall of the seventh slider, and the rotating objective lens is mounted on the objective lens support plate. The rear side wall of the seventh slider is provided with an objective lens conversion motor support plate, the objective lens conversion motor support plate is provided with a ninth motor, the main shaft of the ninth motor is provided with a pulley, and the rotating part of the objective lens is connected to the pulley by a belt for transmission.

9. The slide reading module of the liquid-based cell preparation, staining, mounting, and reading integrated machine according to claim 8, characterized in that, The objective lens includes an objective lens disk, a light guide tube is embedded on the top of the objective lens disk, an objective lens support plate is clamped to the outside of the upper end of the light guide tube, a rotating ring is rotatably arranged on the outside of the objective lens disk, one end of the belt is fitted on the outside of the rotating ring, an objective lens mounting plate is arranged below the rotating ring, and multiple objective lenses are embedded in a circular array along the center of the lower surface of the objective lens mounting plate. The light emitted by the condenser light source passes upward through the condenser, the glass slide in the slide groove, one of the objective lenses, the light guide tube, the first through hole, and then enters the light entrance end of the lens.

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