Microfluidic fractionation module for plant active ingredients
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- YANGZHOU XIE FUCHUN CLASSICAL COSMETICS CO LTD
- Filing Date
- 2025-08-27
- Publication Date
- 2026-08-07
AI Technical Summary
[0003]现有的微流控萃取模块通常是将样品和与萃取剂在蛇形流道内部的充分接触进行萃取混合,蛇形流道存在多段直流道,样品和萃取液只在蛇形流道的弯曲处碰撞混合的力度较大,导致存取过程中需要经过较长的一段蛇形流道才便于使样品充分混合萃取,萃取速率较慢,且不便于使多个微流控萃取模块快速组装,对萃取液进行多次萃取
[0025]1、通过连接杆和插槽的插接,在限位环的限位作用下,将两个主体连接,并在两者之间撑开固定距离,便于对分离组件进行放置和固定,也便于根据萃取要求,自由调节萃取的次数。
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Figure CN224598784U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of plant active ingredient extraction technology, specifically a microfluidic fractional extraction module for plant active ingredients. Background Technology
[0002] Plants, as an important treasure trove of natural active ingredients, contain compounds with diverse structures and functions. These active ingredients have extremely high application value in the pharmaceutical, health product, cosmetic, and food industries. The efficient and selective separation and enrichment of target ingredients from complex plant matrices has always been a core challenge and bottleneck in natural product research and development. To overcome these bottlenecks, researchers are constantly seeking more efficient, green, and intelligent separation technologies. The rise of microfluidics technology has provided a revolutionary approach to solving the above problems.
[0003] Existing microfluidic extraction modules typically involve mixing the sample and extractant through thorough contact within a serpentine channel. This serpentine channel has multiple straight sections, and the sample and extractant only experience significant mixing at the bends. This results in a relatively long traversal of the serpentine channel during storage and retrieval to ensure adequate mixing and extraction, leading to a slow extraction rate. Furthermore, it hinders the rapid assembly of multiple microfluidic extraction modules for repeated extractions of the extractant. Utility Model Content
[0004] The purpose of this invention is to provide a microfluidic fractional extraction module for plant active ingredients to solve the problems mentioned in the background art.
[0005] To achieve the above objectives, this utility model provides the following technical solution:
[0006] The microfluidic fractional extraction module for plant active ingredients includes:
[0007] Multiple extraction components, each extraction component includes a main body, the main body having a Y-shaped flow channel inside, multiple serpentine flow channels symmetrically arranged at equal intervals inside the main body, and a second confluence channel between the multiple serpentine flow channels;
[0008] Multiple spiral components are respectively installed inside the Y-shaped flow channel and the No. 2 confluence channel;
[0009] A separation component is positioned between the two extraction components;
[0010] A connecting assembly is disposed between two extraction assemblies. The connecting assembly includes multiple connecting rods, and limit rings are symmetrically fixedly installed at both ends of the outer surface of the connecting rods.
[0011] Furthermore, slots are provided at the four corners of one side surface of the main body, and the connecting rod is movably inserted into the slots at the corresponding positions.
[0012] Furthermore, the spiral assembly includes:
[0013] Fixed rod;
[0014] The spiral blades are fixedly installed on the outer surface of the fixed rod.
[0015] Multiple stop bars are fixedly installed at equal intervals on the outer surface of the fixed bar.
[0016] Preferably, the helical blades of the plurality of helical assemblies are fixedly connected to the Y-shaped flow channel and the second confluence channel at their respective positions.
[0017] Furthermore, two liquid inlet holes communicating with the Y-shaped flow channel are opened on one side surface of the main body.
[0018] Preferably, a No. 1 confluence channel is provided at one end of the body, which is connected to two symmetrical serpentine flow channels, and an outlet hole is provided on the other side surface of the body, which is connected to the No. 1 confluence channel.
[0019] Preferably, the separation component includes:
[0020] Two retaining rings are symmetrically fixedly installed on both sides of the main body;
[0021] The separation compartment is movably inserted into the inner side of the retaining ring on one side of the two main bodies;
[0022] The inlet pipe is fixedly installed on one side of the separation chamber and is movably connected to the outlet hole above.
[0023] The heavy phase outlet pipe is fixedly installed on the other side of the separation chamber and is movably connected to one of the inlet ports below.
[0024] Compared with the prior art, the beneficial effects of this utility model are:
[0025] 1. By connecting the connecting rod and the slot, the two main bodies are connected under the limiting action of the limiting ring, and a fixed distance is spread between them, which facilitates the placement and fixation of the separation component, and also facilitates the free adjustment of the number of extractions according to the extraction requirements.
[0026] 2. The sample and extract enter through two inlet ports respectively. They are first initially mixed by the spiral assembly inside the Y-shaped flow channel, and then dispersed into two symmetrical serpentine flow channels. After multiple collisions and mixing inside the serpentine flow channels, they converge into the second confluence channel. After being mixed by the spiral assembly, they re-enter the two symmetrical serpentine flow channels. After repeating this process several times, the fully mixed extract solution is discharged from the outlet port and enters the separation component for separation. By converging between multiple serpentine flow channels and shortening the direct current distance of the serpentine flow channels, the collision points of the serpentine flow channels are increased within the same distance, allowing the mixed sample and extract to collide and mix multiple times, thus accelerating the sample extraction and mixing speed.
[0027] 3. As the sample and extract flow through the spiral assembly, the spiral blades increase the flow path of the sample and extract while causing them to rotate. The baffle cuts and mixes the rotating sample and extract, thereby further dispersing and mixing the mixed sample and extract, which further accelerates the extraction and mixing speed of the sample. Attached Figure Description
[0028] Figure 1 This is a schematic diagram of the overall structure of this utility model;
[0029] Figure 2 This is a schematic diagram of the overall disassembled structure of this utility model;
[0030] Figure 3 This is a schematic diagram of the vertical cross-sectional structure of the two extraction components in this utility model;
[0031] Figure 4 This is a schematic diagram of the cross-sectional structure of the extraction component in this utility model;
[0032] Figure 5 This is a schematic diagram of the overall structure of the spiral assembly in this utility model.
[0033] In the diagram: 1. Extraction assembly; 101. Main body; 102. Liquid inlet; 103. Y-shaped flow channel; 104. Serpentine flow channel; 105. No. 1 confluence channel; 106. Liquid outlet; 107. No. 2 confluence channel; 2. Spiral assembly; 201. Fixing rod; 202. Spiral blade; 203. Baffle; 3. Separation assembly; 301. Snap ring; 302. Separation chamber; 303. Liquid inlet pipe; 304. Heavy phase liquid outlet pipe; 4. Connecting assembly; 401. Connecting rod; 402. Slot; 403. Limiting ring. Detailed Implementation
[0034] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0035] Please see Figure 1-5 In this embodiment of the present invention, the microfluidic graded extraction module for plant active ingredients includes multiple extraction components 1. Each extraction component 1 includes a main body 101, with a Y-shaped flow channel 103 inside the main body 101. Multiple serpentine flow channels 104 are symmetrically arranged at equal intervals inside the main body 101. A second confluence channel 107 is provided between the multiple serpentine flow channels 104. Multiple spiral components 2 are respectively disposed inside the Y-shaped flow channel 103 and the second confluence channel 107. A separation component 3 is disposed between two extraction components 1. A connecting component 4 is disposed between two extraction components 1. The connecting component 4 includes multiple connecting rods 401. Limiting rings 403 are symmetrically fixedly installed at both ends of the outer surface of the connecting rods 401.
[0036] Specifically, the sample and extract are mixed and extracted multiple times through multiple extraction components 1 to achieve staged extraction. The mixing speed between the sample and extract is increased by the spiral component 2. The connecting component 4 facilitates the assembly and connection of multiple extraction components 1. The separation component 3 separates the sample after each stage of extraction, separating the light phase and the heavy phase, discharging the light phase and allowing the heavy phase to enter the next stage of extraction.
[0037] Example 1
[0038] like Figure 2 and Figure 3 As shown, in this embodiment, slots 402 are provided at the four corners of one side surface of the main body 101, and the connecting rod 401 is movably inserted into the slots 402 at the corresponding positions.
[0039] In this embodiment, the two main bodies 101 are connected by the insertion of the connecting rod 401 and the slot 402, and the limiting ring 403 limits the connection, and a fixed distance is spread between them, which facilitates the placement and fixing of the separation component 3, and also facilitates the free adjustment of the number of extractions according to the extraction requirements.
[0040] like Figure 4 As shown, in this embodiment, two liquid inlet holes 102 are opened on one side surface of the main body 101 and are connected to the Y-shaped flow channel 103; a first confluence channel 105 is opened at one end of the interior of the main body 101 and is connected to two symmetrical serpentine flow channels 104; and a liquid outlet hole 106 is opened on the other side surface of the main body 101 and is connected to the first confluence channel 105.
[0041] In practice, the sample and extract enter through two inlet holes 102 respectively. They are first initially mixed by the spiral component 2 inside the Y-shaped flow channel 103, and then dispersed into two symmetrical serpentine flow channels 104. After multiple collisions and mixing inside the serpentine flow channels 104, they converge into the second confluence channel 107. After being mixed by the spiral component 2, they re-enter the two symmetrical serpentine flow channels 104. After repeating the above operation several times, the fully mixed extract solution is discharged from the outlet hole 106 and enters the separation component 3 for separation. Thus, by converging between multiple serpentine flow channels 104 and shortening the direct current distance of the serpentine flow channels 104, the collision points of the serpentine flow channels 104 are increased within the same distance, causing the mixed sample and extract to collide and mix multiple times, thereby accelerating the extraction and mixing speed of the sample.
[0042] like Figure 1 and Figure 2 As shown, in this embodiment, the separation component 3 includes: two retaining rings 301 symmetrically fixedly installed on both sides of the main body 101; a separation chamber 302 movably inserted into the inner side of the retaining rings 301 on one side of the two main bodies 101; an inlet pipe 303 fixedly installed on one side of the separation chamber 302 and movably inserted into the outlet hole 106 above; and a heavy phase outlet pipe 304 fixedly installed on the other side of the separation chamber 302 and movably inserted into one inlet hole 102 below.
[0043] In practice, the solution after mixed extraction enters the separation chamber 302 and is separated by the membrane separation structure set inside the separation chamber 302, so that the heavy phase enters the next extraction component 1 for extraction, and the light phase is discharged from the top of the separation chamber 302, thus realizing multi-stage extraction.
[0044] Example 2
[0045] Based on Example 1, in order to compensate for the problem that the sample and extract can only be easily mixed by collision inside the No. 2 confluence channel 107, the extraction speed is poor.
[0046] like Figure 5 As shown, in this embodiment, the spiral assembly 2 includes a fixed rod 201, spiral blades 202 are fixedly installed on the outer surface of the fixed rod 201, and multiple baffles 203 are fixedly installed at equal intervals on the outer surface of the fixed rod 201; the spiral blades 202 of the multiple spiral assemblies 2 are fixedly connected to the Y-shaped flow channel 103 and the second confluence channel 107 at their respective positions.
[0047] In practice, when the sample and extract flow through the spiral assembly 2, the spiral blades 202 increase the flow path of the sample and extract, and at the same time make them rotate. The baffle 203 cuts and mixes the rotating sample and extract, thereby breaking up and mixing the mixed sample and extract again, further accelerating the extraction and mixing speed of the sample.
[0048] It will be apparent to those skilled in the art that this invention is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this invention. Therefore, the embodiments should be considered illustrative and non-limiting in all respects, and the scope of this invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this invention. No reference numerals in the claims should be construed as limiting the scope of the claims.
[0049] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.
Claims
1. A microfluidic fractional extraction module for plant active ingredients, characterized in that, include: Multiple extraction components (1), each extraction component (1) includes a main body (101), the main body (101) has a Y-shaped flow channel (103) inside, the main body (101) has multiple serpentine flow channels (104) symmetrically arranged at equal intervals inside, and a second confluence channel (107) is provided between the multiple serpentine flow channels (104). Multiple spiral components (2) are respectively disposed inside the Y-shaped flow channel (103) and the second confluence channel (107); A separation component (3) is positioned between two extraction components (1); A connecting component (4) is disposed between two extraction components (1). The connecting component (4) includes multiple connecting rods (401), and limit rings (403) are symmetrically fixed at both ends of the outer surface of the connecting rods (401).
2. The microfluidic fractional extraction module for plant active ingredients according to claim 1, characterized in that, The main body (101) has slots (402) at the four corners of one side surface, and the connecting rod (401) is movably inserted into the slots (402) at the corresponding positions.
3. The microfluidic fractional extraction module for plant active ingredients according to claim 1, characterized in that, The spiral assembly (2) includes: Fixed rod (201); The spiral blade (202) is fixedly installed on the outer surface of the fixing rod (201); Multiple stop bars (203) are fixedly installed at equal intervals on the outer surface of the fixed bar (201).
4. The microfluidic fractional extraction module for plant active ingredients according to claim 3, characterized in that, The spiral blades (202) of the multiple spiral components (2) are fixedly connected to the Y-shaped flow channel (103) and the second confluence channel (107) at the corresponding positions.
5. The microfluidic fractional extraction module for plant active ingredients according to claim 1, characterized in that, Two liquid inlet holes (102) are provided on one side surface of the main body (101) and are connected to the Y-shaped flow channel (103).
6. The microfluidic fractional extraction module for plant active ingredients according to claim 5, characterized in that, The main body (101) has a first confluence channel (105) at one end of its interior, which is connected to two symmetrical serpentine channels (104). The other side surface of the main body (101) has a liquid outlet hole (106) connected to the first confluence channel (105).
7. The microfluidic fractional extraction module for plant active ingredients according to claim 6, characterized in that, The separation component (3) includes: Two retaining rings (301) are symmetrically fixedly installed on both sides of the main body (101); The separation compartment (302) is movably inserted into the inside of the retaining ring (301) on one side of the two main bodies (101); The inlet pipe (303) is fixedly installed on one side of the separation chamber (302) and is movably connected to the outlet hole (106) above; The heavy phase outlet pipe (304) is fixedly installed on the other side of the separation chamber (302) and is movably connected to a liquid inlet (102) below.