Platelet-rich plasma preparation system

Abstract

The application relates to the technical field of medical equipment, and provides a platelet-rich plasma preparation system. The platelet-rich plasma preparation system comprises a shell, an accommodating space is formed in the shell, a first collecting part, a first shell and a first driving part arranged in the shell, a first separation cavity for accommodating blood is formed in the first shell, a second collecting part, a second shell and a second driving part which are detachably connected to the shell, a second separation cavity is formed in the second shell, a three-way valve arranged in the shell and communicated with the first shell and the second shell is used for controlling the on-off of the first separation cavity, the second separation cavity and the accommodating space, the first driving part is mounted on the first shell, the second driving part is mounted on the second shell, and at least part of regions of the shell, the first shell and the second shell are transparent, so that the liquid state in the first separation cavity and the second separation cavity can be observed.

Description

Technical Field

[0001] This application relates to the field of medical device technology, and in particular to a platelet-rich plasma preparation system. Background Technology

[0002] Platelet-rich plasma (PRP) is a platelet concentrate obtained by centrifuging autologous whole blood. Its core value lies in the various growth factors, cytokines, and antimicrobial peptides released after platelet activation. These substances can synergistically promote tissue repair and regeneration, thus demonstrating good clinical effects in multiple fields such as oral and maxillofacial surgery, orthopedics, and burn surgery.

[0003] Existing technologies often employ a two-stage centrifugation method to prepare platelet-rich plasma (PRP): First, autologous blood is drawn into an initial container. After a first low-speed centrifugation, the blood separates into a bottom red blood cell layer, a middle PRP layer, and a supernatant. Then, the middle PRP and supernatant are manually transferred to a second container. A second centrifugation is performed in the second container, causing the blood components to separate into a supernatant layer and a bottom PRP layer. After removing the supernatant, the PRP is collected to obtain the final desired PRP. However, during the transfer of the supernatant and PRP layers from the first low-speed centrifugation, these layers are exposed to external conditions, making them highly susceptible to contamination and leakage. Utility Model Content

[0004] In order to solve the above-mentioned technical problems, or at least partially solve the above-mentioned technical problems, this application provides a platelet-rich plasma preparation system.

[0005] This application provides a platelet-rich plasma preparation system, comprising:

[0006] The outer shell has an internal space for storage.

[0007] The first collection unit includes a first housing and a first drive unit disposed within the outer casing, wherein a first separation chamber for containing blood is formed inside the first housing;

[0008] The second collection part is detachably connected to the outer casing and includes a second housing and a second drive part. A second separation chamber is formed inside the second housing.

[0009] A three-way valve is disposed inside the housing and communicates with the first housing and the second housing to control the opening and closing of the first separation chamber, the second separation chamber and the receiving space;

[0010] The first drive unit is mounted on the first housing to drive the middle plasma layer and the upper clear liquid after the initial centrifugation separation in the first separation chamber to be transported to the second separation chamber through the three-way valve;

[0011] The second drive unit is mounted on the second housing to drive the supernatant liquid after secondary centrifugal separation in the second separation chamber to be discharged into the receiving space through the three-way valve;

[0012] At least a portion of the outer shell, the first housing, and the second housing are transparent to allow observation of the liquid state within the first separation chamber and the second separation chamber.

[0013] Optionally, the first drive unit includes a rotating shaft; a first opening is formed on the first housing, and the inner wall of the first opening and the outer wall of the rotating shaft are both provided with threads;

[0014] The rotating shaft is threaded into the first opening, and there is a sealed connection between the rotating shaft and the inner wall of the first opening;

[0015] When the rotating shaft rotates relative to the first housing, the rotating shaft can move axially toward the interior of the first separation chamber under the action of the thread, so as to push the liquid in the first separation chamber to be output into the second separation chamber.

[0016] Optionally, the first collecting part further includes a cover, which is detachably connected to the first housing, and the cover covers the rotating shaft and is exposed on the outside of the housing.

[0017] Optionally, a second opening is formed on the second housing;

[0018] The second drive unit includes a push rod, which is slidably connected to the second opening and is sealed to the inner wall of the second opening;

[0019] The push rod can slide along the axial direction of the second opening toward the interior of the second separation chamber to drive the liquid in the second separation chamber to be output to the receiving space.

[0020] Optionally, the housing is provided with an adjustment hole, the three-way valve includes a valve body and a control rod, the valve body is fixedly connected to the receiving space, and the control rod extends to the outside of the housing through the adjustment hole.

[0021] Optionally, the outer shell, the first housing, and the second housing are all transparent.

[0022] Optionally, a mounting bracket is connected inside the outer casing, and the second casing is snapped into the mounting bracket.

[0023] Optionally, the mounting bracket has threads on its outer side and the inner wall of the housing has threads, and the mounting bracket is threaded into the housing.

[0024] Optionally, the outer casing is cylindrical, and the first casing and the second casing are disposed at both ends of the three-way valve along the axial direction of the outer casing.

[0025] Optionally, the first housing is sealed to the inner wall of the outer shell, and the second housing is sealed to the inner wall of the outer shell, so that the outer shell, the first housing, and the second housing together define a sealed storage cavity for storing the supernatant discharged from the second separation cavity.

[0026] The technical solution provided in this application has the following advantages compared with the prior art:

[0027] The platelet-rich plasma (PRP) preparation system provided in this application comprises a first housing, a second housing, and a three-way valve installed within an outer casing. The first and second housings are connected to the three-way valve, which controls the sealing or connection between the first separation chamber, the second separation chamber, and the receiving space. A first driving unit drives the liquid in the first separation chamber to be output into the second separation chamber, and a second driving unit drives the liquid in the second separation chamber to be output into the receiving space. After the blood in the first separation chamber undergoes a first centrifugation, the supernatant and the middle plasma layer are driven by the first driving unit to enter the second separation chamber through the three-way valve, avoiding contact with the outside environment during liquid transfer after the first centrifugation and effectively reducing the risk of contamination and leakage. Furthermore, after a second centrifugation in the second separation chamber, the second driving unit drives the supernatant in the second separation chamber to be discharged into the receiving space through the three-way valve, leaving the PRP in the second separation chamber. By disassembling the second housing, the desired PRP can be obtained. By controlling the connection and separation of the first separation chamber, the second separation chamber, and the containment space through a three-way valve, secondary centrifugation of blood can be achieved in a closed environment, avoiding leakage and contamination during the preparation of platelet-rich plasma. Attached Figure Description

[0028] The accompanying drawings, which are incorporated in and form part of this specification, illustrate embodiments consistent with this application and, together with the description, serve to explain the principles of this application.

[0029] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, for those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0030] Figure 1 This is a cross-sectional view of the platelet-rich plasma preparation system described in the embodiments of this application;

[0031] Figure 2 This is an exploded view of the platelet-rich plasma preparation system described in the embodiments of this application;

[0032] Figure 3 This is a schematic diagram of the platelet-rich plasma preparation system described in the embodiments of this application.

[0033] Among them, 1. outer shell; 11. accommodating space; 2. first collecting part; 21. first separating chamber; 22. first housing; 23. first driving part; 24. cover; 3. second collecting part; 31. second separating chamber; 32. second housing; 33. second driving part; 34. mounting bracket; 4. three-way valve; 41. valve body; 42. control lever. Detailed Implementation

[0034] To better understand the above-mentioned objectives, features, and advantages of this application, the solution of this application will be further described below. It should be noted that, unless otherwise specified, the embodiments and features described in these embodiments can be combined with each other.

[0035] Many specific details are set forth in the following description in order to provide a full understanding of this application, but this application may also be implemented in other ways different from those described herein; obviously, the embodiments in the specification are only some embodiments of this application, and not all embodiments.

[0036] Reference Figures 1 to 3 As shown, this application provides a platelet-rich plasma preparation system, including a shell 1, a first collection section 2, and a second collection section 3; the shell 1 has an internal accommodating space; the first collection section 2 includes a first housing 22 and a first driving section 23 disposed within the shell 1, and the first housing 22 has a first separation chamber 21 for accommodating blood; the second collection section 3 is detachably connected to the shell 1, including a second housing 32 and a second driving section 33, and the second housing 32 has a second separation chamber 31 formed inside; a three-way valve 4 is disposed within the shell 1 and communicates with the first housing 22 and the second housing 32 to... The system controls the connection and disconnection between the first separation chamber 21, the second separation chamber 31, and the receiving space; the first drive unit 23 is mounted on the first housing 22 to drive the middle plasma layer and the upper clear liquid after the initial centrifugation separation in the first separation chamber 21 to be transported to the second separation chamber 31 through the three-way valve 4; the second drive unit 33 is mounted on the second housing 32 to drive the upper clear liquid after the secondary centrifugation separation in the second separation chamber 31 to be discharged to the receiving space through the three-way valve 4; at least a portion of the outer shell 1, the first housing 22, and the second housing 32 are transparent to allow observation of the liquid state in the first separation chamber 21 and the second separation chamber 31.

[0037] Specifically, the outer casing 1 can be a cuboid or cylindrical structure. It can be made of medical-grade plastic or polycarbonate. The outer casing 1 can be completely transparent, or it can have a transparent observation window to allow personnel to observe the first collecting section 2 and the second collecting section 3. When the outer casing 1 is a cuboid structure, the first collecting section 2 and the second collecting section 3 can be aligned on a straight line. Alternatively, the first collecting section 2 can be connected to one side of the three-way valve 4 along the length of the outer casing 1, and the second collecting section 3 can be connected to one side of the three-way valve 4 along the width of the outer casing 1.

[0038] The first housing 22 can be cylindrical or other shapes. The interior of the first housing 22 is hollow, so that the space inside the first housing 22 serves as the first separation chamber 21. The first housing 22 is provided with an output port and an installation port. The output port is connected to the three-way valve 4, and the first drive unit 23 is installed in the installation port. The first drive unit 23 can be a push rod. The end of the push rod inside the first separation chamber 21 is sealed and fitted against the inner wall of the first separation chamber 21, and the push rod can slide along the axial direction of the installation port. When the push rod moves to reduce the space in the first separation chamber 21 that can store liquid, the air pressure in the first separation chamber 21 increases, which drives the liquid in the first separation chamber 21 to enter the second separation chamber 31 through the three-way valve 4.

[0039] Alternatively, the first drive unit 23 can be a rotating rod, which is threaded into the mounting port. When the rotating rod rotates, it can move toward the inside of the first separation chamber 21 to increase the air pressure in the first separation chamber 21, thereby driving the liquid in the first separation chamber 21 to enter the second separation chamber 31 through the three-way valve 4.

[0040] The outer wall of the first housing 22 may optionally be threaded, and the inner wall of the outer shell 1 may also be threaded. The first housing 22 is threadedly connected to the receiving space 11 within the outer shell 1. Alternatively, the outer shell 1 may have a snap-fit ​​mechanism, and the outer side of the first housing 22 may have a slot. After the first housing 22 is inserted into the outer shell 1, the snap-fit ​​mechanism engages with the slot, thus securing the first housing 22 within the outer shell 1. The first housing 22 may optionally have an injection port with a one-way membrane. Blood is drawn using a syringe and inserted into the injection port to inject the blood into the first housing 22.

[0041] The second housing 32 is a cylindrical structure with a hollow interior, allowing the space inside to serve as the second separation chamber 31. The second housing 32 has an output port and an installation port. The output port is connected to a three-way valve 4, and the second drive unit 33 is installed inside the installation port. The second drive unit 33 can be a push rod, the end of which is sealed against the inner wall of the first separation chamber 21 within the second separation chamber 31. The push rod can slide axially along the installation port, forming a syringe-like structure for the second collecting part 3. When the push rod moves to reduce the liquid storage space within the second separation chamber 31, the air pressure inside the second separation chamber 31 increases, driving the liquid within the second separation chamber 31 through the three-way valve 4 into the receiving space 11.

[0042] Alternatively, the second drive unit 33 can be a rotating rod, which is threaded into the mounting port. When the rotating rod rotates, it can move toward the interior of the second separation chamber 31 to increase the air pressure in the second separation chamber 31, thereby driving the liquid in the second separation chamber 31 to enter the receiving space 11 through the three-way valve 4.

[0043] The inner wall of the outer casing 1 may be provided with threads, and the outer wall of the second casing 32 may also be provided with threads, so that the second casing 32 is threadedly connected to the outer casing 1. Alternatively, a bracket may be fixed inside the outer casing 1, and the second casing 32 may be snapped into the bracket, so that the second casing 32 can be detachably installed inside the outer casing 1.

[0044] Both the first housing 22 and the second housing 32 can be made entirely transparent, allowing the operator to observe the liquid conditions inside the first separation chamber 21 and the second separation chamber 31 through the outer shell 1, the first housing 22, and the second housing 32. Alternatively, a portion of the outer shell 1, a portion of the first housing 22, and a portion of the second housing 32 can be made transparent, forming viewing windows on the outer shell 1, the first housing 22, and the second housing 32. The viewing windows of the outer shell 1 cover the viewing windows of the first housing 22 and the second housing 32, allowing the operator to observe the liquid conditions inside the first separation chamber 21 and the second separation chamber 31 through multiple viewing windows.

[0045] The three-way valve 4 has a T-shaped structure and is made of medical-grade plastic or medical-grade rubber, making it a commonly used medical three-way valve. The three-way valve 4 has three ports. The first housing 22 and the second housing 32 are connected to two ports respectively, and the remaining port communicates with the receiving space inside the outer housing 1. The three-way valve 4 is equipped with a rotatable valve core with a channel inside. Rotating the valve core controls the connection of any two of the three ports.

[0046] When the valve core is in the first position, the first separation chamber 21 is connected to the second separation chamber 31, and the other interfaces are closed; when it is in the second position, the second separation chamber 31 is connected to the receiving space 11 of the outer casing 1; when it is in the third position, all interfaces are closed. The receiving space 11 is used to store the upper clear liquid discharged from the second separation chamber 31, preventing the upper clear liquid from contaminating the external environment.

[0047] In specific use, the platelet-rich plasma preparation system provided in this application embodiment first injects the extracted autologous blood into the first separation chamber 21, closes the three-way valve 4, and positions the valve core in the third position. Then, a first low-speed centrifugation is performed, and the blood separates into three layers: a bottom red blood cell layer, a middle plasma layer with a large number of platelets, and an upper supernatant. The upper supernatant is located on the side of the middle plasma layer with a large number of platelets near the three-way valve 4. The separation is observed through the transparent area of ​​the outer shell 1 and the first collection part 2. The three-way valve 4 is rotated to the first position, driving the middle platelet-rich plasma layer and the upper supernatant located in the middle into the second separation chamber 31.

[0048] After the middle plasma layer and the upper supernatant flow into the second separation chamber 31, the three-way valve 4 is closed, placing the valve core in the third position. Then, the second separation chamber 31 is centrifuged a second time, forming an upper supernatant and a lower platelet-rich plasma layer. The three-way valve 4 is then rotated to the second position, allowing the upper supernatant to be discharged through the three-way valve 4 into the receiving space 11 of the outer shell 1. The receiving space 11 serves as a waste liquid collection point, collecting the upper supernatant and leaving the platelet-rich plasma in the second separation chamber 31.

[0049] Finally, close the three-way valve 4 so that the valve core is in the third position, and disassemble the second collection section 3 to obtain platelet-rich plasma.

[0050] The platelet-rich plasma preparation system provided in this application embodiment has a first housing 22, a second housing 32, and a three-way valve 4 installed inside the outer shell 1. The first housing 22 and the second housing 32 are connected to the three-way valve 4. The three-way valve 4 can control the closure or connection between the first separation chamber 21, the second separation chamber 31, and the receiving space. The liquid in the first separation chamber 21 can be driven to be output to the second separation chamber 31 by the first driving unit 23, and the liquid in the second separation chamber 31 can be driven to be output to the receiving space by the second driving unit 33. After the first centrifugation, the blood in the first separation chamber 21, including the supernatant and the middle plasma layer, can enter the second separation chamber 31 through the three-way valve 4 driven by the first drive unit 23. This avoids contact with the outside environment during liquid transfer after the first centrifugation, effectively reducing the risk of contamination and leakage. After a second centrifugation in the second separation chamber 31, the second drive unit 33 drives the supernatant in the second separation chamber 31 to be discharged into the receiving space 11 through the three-way valve 4, leaving platelet-rich plasma in the second separation chamber 31. By disassembling the second housing 32, the required platelet-rich plasma can be obtained. By controlling the connection and separation of the first separation chamber 21, the second separation chamber 31, and the receiving space 11 through the three-way valve 4, a second centrifugation of blood can be achieved in a closed environment, avoiding leakage and contamination during the preparation of platelet-rich plasma.

[0051] Reference Figure 1 and Figure 2 As shown, in some embodiments, the first drive unit 23 includes a rotating shaft; a first opening is formed on the first housing 22, and the inner wall of the first opening and the outer wall of the rotating shaft are both provided with threads; the rotating shaft is threadedly connected to the first opening, and there is a sealed connection between the rotating shaft and the inner wall of the first opening; when the rotating shaft rotates relative to the first housing 22, the rotating shaft can move axially toward the interior of the first separation chamber 21 under the action of the threads, so as to push the liquid in the first separation chamber 21 to be output to the second separation chamber 31.

[0052] This design allows for manual operation of the threaded shaft structure, eliminating the need for a power supply and improving the portability and reliability of the equipment. The piston's movement distance can be precisely controlled by the number of rotations, thereby accurately controlling the liquid output and adapting to the processing needs of blood samples of different volumes. The mechanical seal structure further reduces the risk of leakage and enhances operational safety.

[0053] Specifically, the first housing 22 has a circular through hole as a first opening. The inner wall of the first opening has an internal thread, and the outer wall of the rotating shaft has an external thread. The rotating shaft is rotatably disposed in the first opening, with the internal and external threads meshing together. A portion of the rotating shaft is exposed outside the first housing 22 through the first opening to facilitate rotation by the operator. When the rotating shaft rotates in the first opening, it can move relative to the first housing 22 along the axial direction of the first opening under the action of the threads.

[0054] Alternatively, a sealing ring can be provided at the edge of the first opening, with the rotating shaft fitting against the sealing ring to create a sealed connection between the rotating shaft and the first opening. Or, the internal and external threads can be engaged, maintaining a close contact to also create a sealed connection between the rotating shaft and the first opening. When the rotating shaft is rotated, it moves axially towards the interior of the first separation chamber under the action of the threads, causing the shaft to compress the liquid within the first separation chamber 21, thereby driving the liquid out of the first separation chamber 21.

[0055] The shaft may be equipped with an injection hole, which contains a one-way diaphragm. After drawing blood with a syringe, the syringe is inserted into the injection hole, and the blood is injected into the first separation chamber 21.

[0056] Reference Figure 1 and Figure 2 As shown, in some embodiments, the first collecting part 2 further includes a cover 24, which is detachably connected to the first housing 22. The cover 24 covers the rotating shaft and is exposed on the outside of the housing 1.

[0057] This design effectively prevents accidental operation and improves equipment safety; it also provides dust and moisture protection, extending the equipment's service life; and the detachable design ensures ease of operation.

[0058] Specifically, the cover 24 has a circular structure, the inner wall of the cover 24 is provided with internal threads, the outer wall of the first housing 22 is provided with threads, and the cover 24 matches the external threads on the top of the first housing 22.

[0059] When the platelet-rich plasma preparation system is not in operation, the cover 24 is threadedly fastened to the first housing 22, completely covering the top of the rotating shaft to prevent liquid leakage due to accidental contact; it also prevents external dust and impurities from contaminating the rotating shaft and the opening. When the rotating shaft needs to be operated, simply rotate and remove the cover 24 to expose the shaft; after operation, the cover 24 can be reinstalled. The outer edge of the cover 24 has a flange, making part of it exposed on the outside of the housing 1 for easy identification and operation by the user. The cover 24 has a through hole in the center, which corresponds to the injection hole of the rotating shaft, allowing the syringe to pass through the through hole and be inserted into the injection hole.

[0060] Reference Figure 1 and Figure 2 As shown, in some embodiments, a second opening is formed on the second housing 32;

[0061] The second drive unit 33 includes a push rod, which is slidably connected to the second opening and is sealed to the inner wall of the second opening.

[0062] The push rod can slide along the axial direction of the second opening toward the interior of the second separation chamber 31 to drive the liquid in the second separation chamber 31 to be output to the receiving space 11.

[0063] With this configuration, the sliding push rod structure enables manual driving of the liquid discharge from the second separation chamber 31, further simplifying the equipment structure and reducing costs; the sliding seal design ensures that the liquid will not leak from the opening, while reducing the resistance to push rod movement; manual operation allows users to control the discharge process in real time based on the observed liquid stratification, facilitating accurate discharge of the supernatant generated by secondary centrifugation.

[0064] Specifically, the top of the second housing 32 is provided with a through hole as a second opening, and the push rod can be made of medical plastic or other materials. The outer wall of the push rod can be fitted to the inner wall of the second opening to maintain a seal between the push rod and the inner wall of the second opening; alternatively, a sealing ring can be provided at the edge of the second opening, with the push rod fitting against the sealing ring to maintain a seal between the push rod and the second opening, and the push rod also maintains a seal with the second opening when sliding.

[0065] The push rod is exposed outside the second housing 32, making it convenient for the operator to drive the push rod to move. When it is necessary to discharge liquid, the operator pushes the handle to move the push rod into the second separation chamber 31, so that the push rod squeezes the liquid and discharges it through the three-way valve 4.

[0066] Reference Figure 1 , Figure 2 and Figure 3 As shown, in some embodiments, the housing 1 is provided with an adjustment hole, and the three-way valve 4 includes a valve body 41 and a control rod 42. The valve body 41 is fixedly connected to the receiving space 11, and the control rod 42 extends to the outside of the housing 1 through the adjustment hole.

[0067] With this configuration, the control lever 42 extends out of the housing 1, making it convenient for the user to control the three-way valve 4. Furthermore, the control lever 42 is located outside the housing 1, which makes it easy to set a clear marking position on the housing 1 to quickly identify the current status of the three-way valve 4 and reduce the risk of operational errors.

[0068] Specifically, the outer casing 1 can be a cylindrical structure with a through hole in the middle for adjustment. The valve body 41 is a tubular structure with three outlets, forming a T-shape. The valve core is installed inside the valve body 41, and its rotation controls the connection or isolation of any two of the three outlets. The valve body 41 has a rotation hole through which the control rod 42 passes and connects to the valve core. Rotation of the control rod 42 drives the valve core to rotate. The valve body 41 can be fixed in the receiving space 11 by bonding or welding. The control rod 42 extends through the adjustment hole, allowing the operator to hold the control rod 42 located on the outside of the outer casing 1 to drive the valve core to rotate.

[0069] The control lever 42 can be fitted against the inner wall of the adjustment hole to create a sealed connection between the control lever 42 and the adjustment hole, preventing liquid inside the housing 1 from leaking to the outside of the housing 1 and causing contamination. Alternatively, a sealing ring can be provided at the edge of the adjustment hole, with the control lever 42 fitting against the inner wall of the sealing ring to create a sealed connection between the control lever 42 and the adjustment hole.

[0070] Reference Figure 1 and Figure 2 As shown, in some embodiments, the outer shell 1, the first housing 22, and the second housing 32 are all transparent.

[0071] This fully transparent structural design enables visualization of the operation process, significantly improving the accuracy and controllability of each step.

[0072] Specifically, the outer shell 1, the first shell 22, and the second shell 32 can all be made of glass or transparent plastic.

[0073] The surfaces of these transparent components are all treated with an anti-fog coating to prevent fogging caused by temperature changes during operation from affecting observation. The front of the outer casing 1 is also provided with scale lines corresponding to the liquid level positions of the first separation chamber 21 and the second separation chamber 31, making it convenient for users to quantitatively observe the liquid volume.

[0074] During centrifugation, the user can observe the stratification of the blood through the transparent outer shell 1 and the first shell 22, accurately determining the interface position of the red blood cell layer, platelet-rich plasma layer, and supernatant. During the liquid transfer stage, the liquid flow status can be monitored in real time to prevent excessive transfer that could result in the red blood cell layer also being introduced into the second separation chamber 31. After the second centrifugation, the boundary between the supernatant and the lower platelet-rich plasma layer can be clearly identified through the transparent second shell 32, ensuring the accuracy of the supernatant discharge.

[0075] Reference Figure 1 and Figure 2 As shown, in some embodiments, a mounting bracket 34 is connected inside the outer casing 1, and the second casing 32 is snapped into the mounting bracket 34.

[0076] This configuration improves the stability of the three-way valve 4 and the second collection section 3, and reduces the vibration and displacement of the second collection section 3 during the centrifugation process.

[0077] Specifically, the mounting bracket 34 can be made of plastic or metal. The mounting bracket 34 is a hollow cylindrical shape. The mounting bracket 34 can be fixed to the inner wall of the outer shell 1 by welding or bonding.

[0078] The mounting bracket 34 has a snap-fit ​​protrusion inside, and the second housing 32 has a slot. After the second housing 32 is inserted into the mounting bracket 34, the snap-fit ​​protrusion snaps into the slot, so that the second collecting part 3 is detachably connected to the mounting bracket 34.

[0079] Alternatively, the inner wall of the mounting bracket 34 can be threaded, the outer wall of the second housing 32 can be threaded, and the second collecting part 3 can be installed inside the mounting bracket 34 and then threadedly connected to the mounting bracket 34 so that the second collecting part 3 can be detachably connected inside the mounting bracket 34.

[0080] Reference Figure 1 and Figure 2 As shown, in some embodiments, the outer side of the mounting bracket 34 is threaded, the inner wall of the housing 1 is threaded, and the mounting bracket 34 is threadedly connected to the housing 1.

[0081] With this configuration, the mounting bracket 34 can be rotated inside the housing 1, thus fixing the mounting bracket 34 inside the housing 1 and simplifying the operation of setting the mounting bracket 34 inside the housing 1.

[0082] Specifically, the mounting bracket 34 is a cylindrical bracket with an installation space for accommodating the second housing 32. The diameter of the mounting bracket 34 is equal to the inner diameter of the housing 1, so that after the mounting bracket 34 is inserted into the housing 1, rotating the mounting bracket 34 within the housing 1 will cause the mounting bracket 34 to be threadedly connected to the housing 1.

[0083] Reference Figure 1 and Figure 2 As shown, in some embodiments, the outer casing 1 is cylindrical, and the first casing 22 and the second casing 32 are disposed at both ends of the three-way valve 4 along the axial direction of the outer casing 1.

[0084] This configuration, with its axially arranged cylindrical structure, results in a shorter and smoother liquid flow path, reducing liquid residue and flow resistance, and improving transfer efficiency. The linear layout facilitates the placement of the entire device within the centrifugal rotor, ensuring that centrifugal force is applied evenly to the liquid and enhancing the stability of the separation effect. The compact structural design reduces the size of the device, improving space utilization and portability.

[0085] Specifically, the outer shell 1 has a hollow cylindrical structure, and the space inside the outer shell 1 forms an accommodating space 11. Both ends of the outer shell 1 can be open, or both ends of the outer shell 1 can be detachably fitted with end caps.

[0086] The first collecting section 2 and the second collecting section 3 are distributed along the axial direction of the outer casing 1 at both ends of the three-way valve 4, with their central axes coinciding to form a straight fluid channel. This layout allows the liquid to flow in a straight line during the transfer process, reducing resistance and liquid residue caused by pipe bends; it also facilitates the placement of the entire system into a centrifuge, improving the separation effect. An axial observation window is provided on the side of the cylindrical outer casing 1, which, together with a transparent component, enables full-process visualization.

[0087] Reference Figure 1 and Figure 2 As shown, in some embodiments, the first housing 22 is sealed to the inner wall of the outer shell 1, and the second housing 32 is sealed to the inner wall of the outer shell 1, so that the outer shell 1, the first housing 22 and the second housing 32 together define a sealed storage cavity for storing the supernatant discharged from the second separation cavity 31.

[0088] This configuration ensures that the upper clear liquid discharged from the second separation chamber 31 can be stored in the storage chamber, preventing the upper clear liquid discharged from the second separation chamber 31 from leaking to the outside of the outer shell 1 and causing pollution.

[0089] Specifically, the first housing 22 and the second housing 32 are disposed on both sides of the three-way valve 4. The first housing 22 is sealed to the inner wall of the outer shell 1, and the second housing 32 is sealed to the inner wall of the outer shell 1, so that the space between the first housing 22 and the second housing 32 is a sealed storage cavity. When the three-way valve 4 is adjusted to connect the second separation chamber 31 with the receiving space, the second separation chamber 31 is connected to the storage cavity, and the supernatant discharged from the second separation chamber 31 can be stably stored in the storage cavity.

[0090] When the second housing 32 is disassembled, the first housing 22 is located below the second housing 32, and the upper layer of blood in the storage cavity will not leak when the second housing 32 is removed from the outer shell 1.

[0091] In specific use, the platelet-rich plasma preparation system provided in this embodiment first injects the extracted autologous blood into the first separation chamber 21 within the first housing 22, closes the three-way valve 4 so that the valve core is in the third position, and then performs a first low-speed centrifugation, separating the blood into a bottom red blood cell layer, a middle platelet-rich plasma layer, and an upper clear liquid. In the first separation chamber 21, the upper clear liquid is located on the side near the three-way valve 4, and the separation is observed through the transparent area of ​​the housing 1 and the first collection part 2. The three-way valve 4 is rotated to the first position; the rotating shaft is then rotated to drive the middle platelet-rich plasma layer and the upper clear liquid into the second separation chamber 31.

[0092] After the platelet-rich plasma layer and the supernatant flow into the second separation chamber 31, the three-way valve 4 is closed, placing the valve core in the third position. The liquid in the second separation chamber 31 is then centrifuged a second time, forming a supernatant and a lower platelet-rich plasma layer. The three-way valve 4 is then rotated to the second position, pushing the push rod to discharge the supernatant through the three-way valve 4 into the receiving space 11 of the outer casing 1. The receiving space 11 serves as a waste liquid collection point, collecting the supernatant and leaving the platelet-rich plasma within the second separation chamber 31.

[0093] Finally, close the three-way valve 4 to put the valve core in the third position, and remove the second collection part 3 from the mounting bracket 34 to obtain platelet-rich plasma.

[0094] It should be noted that, in this document, relational terms such as "first" and "second" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0095] The above description is merely a specific embodiment of this application, enabling those skilled in the art to understand or implement this application. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of this application. Therefore, this application is not to be limited to the embodiments described herein, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A platelet-rich plasma preparation system, characterized in that, include: The outer shell (1) has an internal space for accommodating the interior; The first collection unit (2) includes a first housing (22) disposed inside the outer shell (1) and a first drive unit (23), wherein a first separation chamber (21) for containing blood is formed inside the first housing (22); The second collection part (3) is detachably connected to the outer shell (1) and includes a second housing (32) and a second drive part (33). A second separation chamber (31) is formed inside the second housing (32). A three-way valve (4) is disposed inside the housing (1) and communicates with the first housing (22) and the second housing (32) to control the opening and closing of the first separation chamber (21), the second separation chamber (31) and the accommodating space; The first drive unit (23) is installed on the first housing (22) to drive the middle plasma layer and the upper clear liquid after the initial centrifugation separation in the first separation chamber (21) to be transported to the second separation chamber (31) through the three-way valve (4); The second drive unit (33) is installed on the second housing (32) to drive the upper clear liquid after secondary centrifugal separation in the second separation chamber (31) to be discharged into the receiving space through the three-way valve (4); At least a portion of the outer shell (1), the first housing (22), and the second housing (32) are transparent to allow observation of the liquid state within the first separation chamber (21) and the second separation chamber (31).

2. The platelet-rich plasma preparation system according to claim 1, characterized in that, The first drive unit (23) includes a rotating shaft; a first opening is formed on the first housing (22), and the inner wall of the first opening and the outer wall of the rotating shaft are both provided with threads; The rotating shaft is threaded into the first opening, and there is a sealed connection between the rotating shaft and the inner wall of the first opening; When the rotating shaft rotates relative to the first housing (22), the rotating shaft can move axially toward the interior of the first separation chamber (21) under the action of the thread, so as to push the liquid in the first separation chamber (21) to be output into the second separation chamber (31).

3. The platelet-rich plasma preparation system according to claim 2, characterized in that, The first collecting part (2) also includes a cover (24), which is detachably connected to the first housing (22). The cover (24) covers the rotating shaft and is exposed on the outside of the outer shell (1).

4. The platelet-rich plasma preparation system according to claim 1, characterized in that, A second opening is formed on the second housing (32); The second drive unit (33) includes a push rod, which is slidably connected to the second opening and is sealed to the inner wall of the second opening; The push rod can slide along the axial direction of the second opening toward the interior of the second separation chamber (31) to drive the liquid in the second separation chamber (31) to be output to the receiving space (11).

5. The platelet-rich plasma preparation system according to claim 1, characterized in that, The outer casing (1) is provided with an adjustment hole. The three-way valve (4) includes a valve body (41) and a control rod (42). The valve body (41) is fixedly connected to the accommodating space (11). The control rod (42) extends out to the outside of the outer casing (1) through the adjustment hole.

6. The platelet-rich plasma preparation system according to claim 1, characterized in that, The outer shell (1), the first shell (22) and the second shell (32) are all transparent.

7. The platelet-rich plasma preparation system according to claim 1, characterized in that, The housing (1) is connected to a mounting bracket (34), and the second housing (32) is snapped into the mounting bracket (34).

8. The platelet-rich plasma preparation system according to claim 7, characterized in that, The mounting bracket (34) has threads on its outer side, and the inner wall of the outer shell (1) has threads. The mounting bracket (34) is threaded into the outer shell (1).

9. The platelet-rich plasma preparation system according to claim 1, characterized in that, The outer casing (1) is cylindrical, and the first casing (22) and the second casing (32) are disposed at both ends of the three-way valve (4) along the axial direction of the outer casing (1).

10. The platelet-rich plasma preparation system according to claim 9, characterized in that, The first housing (22) is sealed to the inner wall of the outer shell (1), and the second housing (32) is sealed to the inner wall of the outer shell (1) so that the outer shell (1), the first housing (22) and the second housing (32) together define a sealed storage cavity for storing the supernatant discharged from the second separation cavity (31).

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