A medicine detecting dissolving device with a particle grinding structure

Abstract

The utility model provides a kind of medicine detection dissolving device with granule grinding structure, comprising: drive assembly, dissolving component, the drive assembly front end is fixed with dissolving component, the drive assembly includes base, stand and shaft sleeve, compared with prior art, the utility model has the following beneficial effects: by setting grinding piece one and grinding piece two, under the synergistic grinding of upper grinding head, lower grinding head and grinding inner lining, granule medicament is gradually ground and refined, until become small powder from lower grinding head lower end edge, under the action of guide skirt, it will not fall and accumulate on the inner wall of shell, by refining grinding to granule medicament, it helps to improve the dissolving efficiency of granule medicament, by setting dissolving tank cooperation stirring piece, powder-shaped medicament can better contact with dissolving solution, can make the granule medicament required to be detected faster dissolution, avoid the problem of slow granule medicament dissolution rate and incomplete dissolution.

Description

Technical Field

[0001] This utility model belongs to the technical field of drug detection equipment, and specifically relates to a drug detection and dissolution device with a particle grinding structure. Background Technology

[0002] Existing drug detection and dissolution devices suffer from incomplete dissolution during the dissolution of particulate drugs. This is primarily manifested in low dissolution efficiency and poor particle dispersion. Many traditional devices, especially when processing large or high-density drugs, often fail to achieve effective liquid flow and sufficient particle contact. Particle aggregation prevents adequate liquid penetration, further reducing the dissolution rate.

[0003] To address these issues, common approaches include increasing stirring speed, improving liquid flowability, adjusting dissolution time, and selecting more suitable solvents. However, these methods often fail to fundamentally solve the problem, and extending dissolution time increases experimental costs and time consumption, reducing work efficiency. Improving the solvent or adding surfactants may enhance solubility to some extent, but this method may cause drug interactions, affecting drug bioavailability and safety. Therefore, we aim to design a novel drug detection and dissolution device to address this problem. Utility Model Content

[0004] In view of the shortcomings of the existing technology, the purpose of this utility model is to provide a drug detection and dissolution device with a particle grinding structure, so as to solve the problems mentioned in the background art.

[0005] This utility model is achieved through the following technical solution: a drug detection and dissolution device with a particle grinding structure, comprising: a driving component and a dissolution component, wherein the dissolution component is fixed at the front end of the driving component, the driving component includes a base, a stand and a bushing, the stand is installed on the upper side of the base, and the bushing is fixed at the front side of the upper end of the stand;

[0006] The dissolving assembly includes a dissolving tank, a first grinding component, and a second grinding component. The upper end of the dissolving tank is movably mounted on the lower end of the first grinding component, and the second grinding component is rotatably mounted inside the first grinding component.

[0007] In a preferred embodiment, a connecting plate is fixed to the upper end of the dissolving tank. A screw is welded to the left and right sides of the upper surface of the connecting plate, and a locking sleeve is threaded to the upper side of each screw. In actual use, the dissolving tank can be made of glass for easy viewing.

[0008] In a preferred embodiment, the dissolving tank is integrally provided with an inlet / outlet pipe on the upper right side, and the connecting plate forms a through hole extending downward through the middle. A fixing frame is welded in the middle of the through hole. The fixing frame includes a support rod and a round block, and three support rods are welded to the edge of the round block in three equal parts.

[0009] In a preferred embodiment, the grinding element includes a shell, a feed pipe, ear plates, and a grinding liner. The lower side of the shell has an inner cavity. The feed pipe is welded to the upper right side of the shell. An ear plate is welded to the left and right sides of the lower end of the shell. An ear plate passes through the upper side of each screw. In actual use, a disc is provided at the upper end of the shell. The upper end of the shell is fixedly connected to the lower end of the bushing through the disc and bolts. The splined sleeve is movably inserted and connected to the drive splined shaft rotatably installed in the middle of the bushing. The drive splined shaft is connected to the drive motor installed inside the upper end of the stand through a belt.

[0010] In a preferred embodiment, the inner wall of the middle part of the inner cavity of the outer shell is provided with a grinding liner, the upper inner wall of the grinding liner is provided with a strip-shaped embossed pattern at a 60-degree angle, and the lower end of the grinding liner convexly forms a guide skirt.

[0011] In a preferred embodiment, the second grinding component includes a spline sleeve, a rotating shaft, an upper grinding head, and a lower grinding head. The spline sleeve is rotatably mounted on the upper side inside the outer shell via the rotating shaft. The lower end of the rotating shaft is fixedly connected to the upper end of the upper grinding head, and the lower grinding head is fixedly attached to the lower end of the upper grinding head.

[0012] A grinding chamber is provided between the upper grinding head and the upper inner wall of the grinding liner, and the width of the cross-section of the grinding chamber gradually decreases from top to bottom.

[0013] In a preferred embodiment, a second grinding cavity is provided between the lower grinding head and the lower inner wall of the grinding liner. The width of the cross-section of the second grinding cavity gradually decreases from top to bottom. The lower end of the second grinding cavity is connected to the upper end of the second grinding cavity. The outer walls of both the upper and lower grinding heads are provided with uniformly distributed concave and convex vertical stripes.

[0014] In a preferred embodiment, a stirring element is rotatably mounted between the dissolving tube and the second grinding element. The stirring element includes a stirring shaft and stirring plates. Multiple stirring plates are fixed at the lower end of the stirring shaft. The upper side of the stirring shaft is rotatably connected to a circular block. The upper end of the stirring shaft is movably inserted into the lower end of the lower grinding head.

[0015] After adopting the above technical solution, the beneficial effects of this utility model are as follows: by setting grinding part one and grinding part two, under the coordinated grinding of the upper grinding head, the lower grinding head and the grinding liner, the granular medicine is gradually ground into fine powder until it falls from the lower edge of the lower grinding head. Under the action of the guide skirt, it will not fall onto the inner wall of the outer shell and accumulate. By refining and grinding the granular medicine, it helps to improve the dissolution efficiency of the granular medicine.

[0016] By setting up a dissolving tank with a stirring element, powdered reagents can come into better contact with the dissolving liquid, allowing the granular reagents to be tested to dissolve faster and avoiding problems such as slow dissolution or incomplete dissolution of granular reagents. Attached Figure Description

[0017] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0018] Figure 1 This is a schematic diagram of the overall structure of a drug detection and dissolution device with a particle grinding structure according to the present invention.

[0019] Figure 2 This is a schematic diagram of the overall structure of the dissolution component of a drug detection and dissolution device with a particle grinding structure according to the present invention.

[0020] Figure 3 This is a schematic cross-sectional view of the dissolution component of a drug detection and dissolution device with a particle grinding structure according to the present invention.

[0021] Figure 4 This is a schematic diagram showing the connection between grinding element one and grinding element two in a drug detection and dissolution device with a particle grinding structure according to this utility model.

[0022] Figure 5 This is a schematic diagram of the dissolving tank structure of a drug detection and dissolving device with a particle grinding structure according to the present invention.

[0023] In the diagram, 100 is the drive assembly, 110 is the base, 120 is the support frame, and 130 is the bushing.

[0024] 200-Dissolving component, 210-Dissolving tank, 211-Connecting plate, 212-Inlet / outlet pipe, 213-Fixed frame, 214-Screw, 215-Locking sleeve, 220-Grinding part one, 221-Outer shell, 222-Feed pipe, 223-Ear plate, 224-Grinding liner, 225-Grinding chamber one, 226-Grinding chamber two, 227-Guide skirt, 230-Grinding part two, 231-Spline sleeve, 232-Rotating shaft, 233-Upper grinding head, 234-Lower grinding head, 240-Stirring component, 241-Stirring shaft, 242-Stirring plate. Detailed Implementation

[0025] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0026] Please see Figures 1 to 5 The present invention provides a technical solution: a drug detection and dissolution device with a particle grinding structure, comprising: a driving component 100 and a dissolution component 200. The dissolution component 200 is fixed at the front end of the driving component 100. The driving component 100 includes a base 110, a support frame 120 and a bushing 130. The support frame 120 is installed on the upper side of the base 110, and the bushing 130 is fixed at the front of the upper end of the support frame 120.

[0027] The dissolving assembly 200 includes a dissolving tank 210, a first grinding component 220, and a second grinding component 230. The upper end of the dissolving tank 210 is movably mounted on the lower end of the first grinding component 220, and the second grinding component 230 is rotatably mounted inside the first grinding component 220.

[0028] Please see Figures 1 to 3 as well as Figure 5 The upper end of the dissolving tank 210 is fixed with a connecting plate 211. A screw 214 is welded to the left and right sides of the upper surface of the connecting plate 211. A locking sleeve 215 is threaded to the upper side of each screw 214. In actual use, the dissolving tank 210 can be made of glass for easy viewing.

[0029] The upper right side of the dissolving tank 210 is integrally provided with an inlet / outlet pipe 212. The connecting plate 211 has a through hole extending downward through the middle. A fixing frame 213 is welded in the middle of the through hole. The fixing frame 213 includes a support rod and a round block. Three support rods are welded to the edge of the round block in three equal parts.

[0030] As the first embodiment of this utility model, by setting up a dissolving tank 210 in conjunction with a stirring element 240, in actual use, the powdered granular agent falls from the lower end of the outer shell 221 into the dissolving tank 210, and under the drive of the lower grinding head 234, the stirring shaft 241 on the stirring element 240 is driven to rotate, which further drives the stirring plate 242 on the lower side of the stirring to rotate inside the dissolving tank 210 (before the granular agent is ground, an appropriate amount of dissolving liquid is injected into the dissolving tank 210 through the inlet and outlet pipes 212 on the upper side of the dissolving tank 210). The powdered agent can better contact the dissolving liquid, which can make the granular agent to be tested dissolve faster and avoid the problems of slow dissolution speed and incomplete dissolution of granular agent.

[0031] Please see Figures 1 to 4 The grinding part 220 includes a housing 221, a feed pipe 222, an ear plate 223, and a grinding liner 224. The lower side of the housing 221 has an inner cavity. The feed pipe 222 is welded to the upper right side of the housing 221. An ear plate 223 is welded to the left and right sides of the lower end of the housing 221. An ear plate 223 passes through the upper side of each screw 214. In actual use, a disc is provided at the upper end of the housing 221. The upper end of the housing 221 is fixedly connected to the lower end of the bushing 130 through the disc and bolts. The spline sleeve 231 is movably inserted into the drive spline shaft that is rotatably installed in the middle of the bushing 130. The drive spline shaft is connected to the drive motor installed inside the upper end of the stand 120 through a belt.

[0032] The inner wall of the middle part of the inner cavity of the outer shell 221 is provided with a grinding liner 224. The upper inner wall of the grinding liner 224 is provided with a strip-shaped embossed pattern at a 60-degree angle. The lower end of the grinding liner 224 bulges inward to form a guide skirt 227.

[0033] Grinding part 230 includes a spline sleeve 231, a rotating shaft 232, an upper grinding head 233 and a lower grinding head 234. The spline sleeve 231 is rotatably mounted on the upper side inside the outer shell 221 via the rotating shaft 232. The lower end of the rotating shaft 232 is fixedly connected to the upper end of the upper grinding head 233. The lower grinding head 234 is fixedly attached to the lower end of the upper grinding head 233.

[0034] A grinding chamber 225 is provided between the upper grinding head 233 and the upper inner wall of the grinding liner 224. The width of the cross-section of the grinding chamber 225 gradually decreases from top to bottom.

[0035] A second grinding cavity 226 is provided between the lower grinding head 234 and the lower inner wall of the grinding liner 224. The width of the cross-section of the second grinding cavity 226 gradually decreases from top to bottom. The lower end of the first grinding cavity 225 is connected to the upper end of the second grinding cavity 226. The outer walls of the upper grinding head 233 and the lower grinding head 234 are provided with uniformly distributed concave and convex vertical stripes.

[0036] A stirring element 240 is rotatably mounted between the dissolving tube and the grinding element 230. The stirring element 240 includes a stirring shaft 241 and stirring plates 242. Multiple stirring plates 242 are fixed at the lower end of the stirring shaft 241. The upper side of the stirring shaft 241 is rotatably connected to the round block. The upper end of the stirring shaft 241 is movably inserted into the lower end of the lower grinding head 234.

[0037] As a second embodiment of this utility model, based on the first embodiment described above, in actual use, the particulate reagent to be tested is fed into the housing 221 through the feed pipe 222. At this time, the drive motor located inside the upper end of the stand 120 drives the spline sleeve 231 connected to it through the drive spline shaft. The spline sleeve 231 drives the upper grinding head 233 and the lower grinding head 234 to rotate inside the grinding liner 224 through the rotating shaft 232. Since the outer walls of the upper grinding head 233 and the lower grinding head 234 are provided with evenly distributed concave and convex vertical stripes, and the upper inner wall of the grinding liner 224 is provided with strip-shaped concave and convex textures at an angle of 60 degrees (the lower inner wall of the grinding liner 224 is designed with a rough texture, and the specific roughness can be set as needed), Furthermore, since a grinding chamber 225 is provided between the upper grinding head 233 and the upper inner wall of the grinding liner 224, and the width of the cross-section of the grinding chamber 225 gradually decreases from top to bottom, and a grinding chamber 226 is provided between the lower grinding head 234 and the lower inner wall of the grinding liner 224, and the width of the cross-section of the grinding chamber 226 gradually decreases from top to bottom, under the synergistic grinding of the upper grinding head 233, the lower grinding head 234 and the grinding liner 224, the granular medicine is gradually ground and refined until it becomes a fine powder that falls from the lower edge of the lower grinding head 234. Under the action of the guide skirt 227, it will not fall onto the inner wall of the outer shell 221 and accumulate. By refining and grinding the granular medicine, the dissolution efficiency of the granular medicine can be improved.

[0038] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A drug detection and dissolution device with a particle grinding structure, comprising: A driving component (100) and a dissolving component (200) are characterized in that the driving component (100) is fixed at its front end and the driving component (100) includes a base (110), a support frame (120) and a bushing (130). The support frame (120) is installed on the upper side of the base (110) and the bushing (130) is fixed on the front side of the upper end of the support frame (120). The dissolving component (200) includes a dissolving tank (210), a first grinding component (220), and a second grinding component (230). The upper end of the dissolving tank (210) is movably installed at the lower end of the first grinding component (220), and the second grinding component (230) is rotatably installed inside the first grinding component (220).

2. The drug detection and dissolution device with a particle grinding structure as described in claim 1, characterized in that: The upper end of the dissolving tank (210) is fixed with a connecting plate (211). A screw (214) is welded to the left and right sides of the upper surface of the connecting plate (211). A locking sleeve (215) is threaded to the upper side of each screw (214).

3. The drug detection and dissolution device with a particle grinding structure as described in claim 2, characterized in that: The dissolving tank (210) is integrally provided with an inlet / outlet pipe (212) on the upper right side. The connecting plate (211) has a through hole extending downward through the middle. A fixing frame (213) is welded in the middle of the through hole. The fixing frame (213) includes a support rod and a round block. Three support rods are welded to the edge of the round block in three equal parts.

4. The drug detection and dissolution device with a particle grinding structure as described in claim 2, characterized in that: The first grinding component (220) includes a shell (221), a feed pipe (222), an ear plate (223), and a grinding liner (224). The lower side of the shell (221) has an inner cavity. The feed pipe (222) is welded to the upper right side of the shell (221). An ear plate (223) is welded to the left and right sides of the lower end of the shell (221). An ear plate (223) is passed through the upper side of each screw (214).

5. The drug detection and dissolution device with a particle grinding structure as described in claim 4, characterized in that: The inner wall of the middle part of the inner cavity of the outer shell (221) is provided with a grinding liner (224). The upper inner wall of the grinding liner (224) is provided with a strip-shaped convex and concave pattern at a 60-degree angle. The lower end of the grinding liner (224) is convex to form a guide skirt (227).

6. The drug detection and dissolution device with a particle grinding structure as described in claim 5, characterized in that: The second grinding component (230) includes a spline sleeve (231), a rotating shaft (232), an upper grinding head (233), and a lower grinding head (234). The spline sleeve (231) is rotatably mounted on the upper side inside the outer shell (221) via the rotating shaft (232). The lower end of the rotating shaft (232) is fixedly connected to the upper end of the upper grinding head (233), and the lower grinding head (234) is fixedly attached to the lower end of the upper grinding head (233). A grinding chamber (225) is provided between the upper grinding head (233) and the upper inner wall of the grinding liner (224), and the width of the cross-section of the grinding chamber (225) gradually decreases from top to bottom.

7. The drug detection and dissolution device with a particle grinding structure as described in claim 6, characterized in that: A second grinding cavity (226) is provided between the lower grinding head (234) and the lower inner wall of the grinding liner (224). The width of the cross-section of the second grinding cavity (226) gradually decreases from top to bottom. The lower end of the first grinding cavity (225) is connected to the upper end of the second grinding cavity (226). The outer walls of the upper grinding head (233) and the lower grinding head (234) are provided with uniformly distributed concave and convex vertical stripes.

8. The drug detection and dissolution device with a particle grinding structure as described in claim 3, characterized in that: A stirring element (240) is rotatably mounted between the dissolving tank (210) and the grinding element (230). The stirring element (240) includes a stirring shaft (241) and stirring plates (242). Multiple stirring plates (242) are fixed at the lower end of the stirring shaft (241). The upper side of the stirring shaft (241) is rotatably connected to the circular block, and the upper end of the stirring shaft (241) is movably inserted into the lower end of the lower grinding head (234).

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