A capsule granule screening device for producing a sustained-release tolterodine tartrate

CN224599779UActive Publication Date: 2026-08-07NANJING MEIRUI PHARMA CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
NANJING MEIRUI PHARMA CO LTD
Filing Date
2025-04-16
Publication Date
2026-08-07

AI Technical Summary

Technical Problem

[0004]现有技术通过横管和出料孔旋转来将药物颗粒均匀的摊铺在筛网上,但是在部分药物颗粒尺寸大于出料口的情况下,药物颗粒堵塞出料孔,进而滞留在横管内部,影响装置的正常运行

Benefits of technology

[0018]在药物颗粒通过进料管进入横管的内部时,通过电源启动慢速电机带动转动杆旋转,与转动杆固定连接的进料管在罐体的内部旋转,使与进料管转动连接的横管在罐体的内部旋转,使药物颗粒通过横管的初次筛分均匀散布在筛分层的表面,进行二次筛分,无法被横管筛分的药物颗粒会通过横管的另一端滑入滞留板的内部,不会滞留在横管的内部,同时与滞留板固定连接的外齿环带动啮合连接的锥齿轮旋转,使与锥齿轮固定连接的横管在旋转的同时自转,进而使横管内部的药物颗粒能够均匀翻滚滑动,与进料管固定连接的固定杆带动上刮板对横管的内壁表面进行刮动,使横管的内部不会滞留药物颗粒,与固定杆固定连接的连接杆带动下刮板在滞留板的内壁表面滑动,将下刮板内部的药物颗粒推向出料口二并进入排料管内部,接着与转动杆固定连接的清洁刮板对筛分层的表面进行清洁,同时清洁的药物颗粒能够随着清洁刮板的弧形设计向罐体的内壁方向移动,然后顺着出料口一进入排料管内部,最后被筛分层筛分的药物颗粒会通过罐体下侧表面的出料口排出。

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Abstract

The utility model discloses a kind of capsule granule screening devices for tartaric acid tolterodine sustained-release production, comprising: main unit, including tank, the one side of tank is equipped with discharge pipe, the inner wall surface of tank is fixedly connected with screening layer, the downside surface of tank is equipped with discharge port.The utility model passes through when medicine granule enters the inside of horizontal pipe through feed pipe, by power supply starting slow motor drives rotating rod rotation, and the feed pipe of fixed connection with rotating rod rotates in the inside of tank, makes and rotates the horizontal pipe of feed pipe rotary connection in the inside of tank, makes medicine granule by horizontal pipe's initial screening even spread on the surface of screening layer, carries out secondary screening, and medicine granule that cannot be screened by horizontal pipe can slide into the inside of stagnation plate by the other end of horizontal pipe, cannot stagnate in the inside of horizontal pipe.
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Description

Technical Field

[0001] This utility model relates to the technical field of drug production, and in particular to a capsule particle screening device for the production of sustained-release tolterodine tartrate. Background Technology

[0002] Tolterodine tartrate sustained-release capsules are a drug used to treat overactive bladder. In the production process of tolterodine tartrate sustained-release capsules, the screening of capsule particles is a key step to ensure the uniformity and consistency of particle quality.

[0003] Existing patent publication number CN220311000U discloses a capsule particle screening device, including a box body. A discharge valve is located on the lower side wall of the box body. An installation ring is installed inside the box body, and an installation cylinder is installed inside the installation ring. A screen is horizontally installed inside the installation cylinder. Multiple vibrating motors are installed on the outside of the installation cylinder. Multiple springs connected to the installation cylinder are vertically installed at the upper end of the installation ring. Multiple air ducts are located on the side wall of the installation cylinder above the screen. An annular pipe connected to each air duct is located on the outside of the installation cylinder. A flexible steel wire hose is connected to the annular pipe. A suction mechanism connected to the flexible steel wire hose is located on the outside of the box body. A vertical pipe is rotatably installed at the upper end of the box body, and a horizontal pipe is connected to the lower end of the vertical pipe. Multiple discharge holes are located at the lower end of the horizontal pipe. This invention has the function of evenly spreading drug particles on a vibrating screen, improving screening efficiency.

[0004] Existing technology uses a rotating horizontal tube and discharge port to evenly spread drug particles on a screen. However, when some drug particles are larger than the discharge port, they block the discharge port and become stuck inside the horizontal tube, affecting the normal operation of the device. Utility Model Content

[0005] The purpose of this section is to outline some aspects of embodiments of the present invention and to briefly describe some preferred embodiments. Simplifications or omissions may be made in this section, as well as in the abstract and title of this application, to avoid obscuring the purpose of these documents; however, such simplifications or omissions should not be construed as limiting the scope of the present invention.

[0006] In view of the problems existing in the above-mentioned capsule particle screening device for sustained-release production of tolterodine tartrate, this utility model is proposed.

[0007] Therefore, the purpose of this utility model is to provide a capsule particle screening device for the production of tolterodine tartrate sustained release, which solves the problem that "the existing technology uses the rotation of the horizontal tube and the discharge hole to evenly spread the drug particles on the screen, but when some drug particles are larger than the discharge hole, the drug particles block the discharge hole and thus remain inside the horizontal tube, affecting the normal operation of the device".

[0008] To solve the above-mentioned technical problems, this utility model provides the following technical solution:

[0009] A capsule particle screening device for the production of tolterodine tartrate sustained-release formulation includes:

[0010] The main unit includes a tank body, a discharge pipe is installed on one side of the tank body, a sieve layer is fixedly connected to the inner wall surface of the tank body, and a discharge port is opened on the lower surface of the tank body;

[0011] The screening unit includes a slow-speed motor fixedly connected to the lower surface of the tank, and a rotating rod fixedly connected to the output end of the slow-speed motor. The surface of the rotating rod is rotatably connected to the screening layer. A feed pipe is fixedly connected to the upper end of the rotating rod, and the feed pipe is rotatably connected to the tank. A horizontal pipe is rotatably connected to one side of the feed pipe, and a retention plate is provided on the lower side of the horizontal pipe. One side of the retention plate is fixedly connected to the inner wall surface of the tank, and a transmission component is provided on the surface of the retention plate.

[0012] As a preferred embodiment of the capsule particle screening device for sustained-release production of tolterodine tartrate described in this utility model, the transmission component includes a bevel gear fixedly connected to the outer surface of the horizontal tube, and an external toothed ring is meshed with one side surface of the bevel gear, the lower surface of the external toothed ring being fixedly connected to the retention plate.

[0013] In a preferred embodiment of the capsule particle screening device for sustained-release production of tolterodine tartrate described in this utility model, a fixing rod is fixedly connected to the inner wall surface of the feed pipe, and an upper scraper is fixedly connected to the upper side surface of the fixing rod. The upper side surface of the upper scraper is movably connected to the inner wall surface of the horizontal pipe.

[0014] In a preferred embodiment of the capsule particle screening device for sustained-release production of tolterodine tartrate described in this utility model, a connecting rod is fixedly connected to the lower surface of the fixed rod, and a lower scraper is fixedly connected to the lower end of the connecting rod. The surface of the lower scraper is slidably connected to the inner wall surface of the retention plate.

[0015] In a preferred embodiment of the capsule particle screening device for sustained-release production of tolterodine tartrate described in this utility model, a cleaning scraper is fixedly connected to one side surface of the rotating rod, and the lower side surface of the cleaning scraper is rotatably connected to the screening layer, wherein the cleaning scraper has an arc-shaped design.

[0016] In a preferred embodiment of the capsule particle screening device for sustained-release production of tolterodine tartrate described in this utility model, a limiting ring is fixedly connected to the outer surface of the horizontal tube, and the surface of the limiting ring is rotatably connected to the feed tube.

[0017] The beneficial effects of this utility model are:

[0018] As the drug granules enter the horizontal tube through the feed pipe, a slow-speed motor is activated to rotate the rotating rod. The feed pipe, fixedly connected to the rotating rod, rotates inside the tank, causing the horizontal tube, also rotated, to rotate as well. This initial sieving of the drug granules in the horizontal tube evenly distributes them across the sieve layer for secondary sieving. Particles that cannot be sieved by the horizontal tube slide into the retention plate at the other end of the tube, preventing them from remaining inside. Simultaneously, the external gear ring, fixedly connected to the retention plate, drives the meshing bevel gear to rotate. This rotation causes the horizontal tube, fixedly connected to the bevel gear, to rotate as well, further dispersing the drug granules inside the horizontal tube. The device can roll and slide evenly. The fixed rod, which is fixedly connected to the feed pipe, drives the upper scraper to scrape the inner wall surface of the horizontal tube, so that no drug particles are retained inside the horizontal tube. The connecting rod, which is fixedly connected to the fixed rod, drives the lower scraper to slide on the inner wall surface of the retention plate, pushing the drug particles inside the lower scraper towards the discharge port 2 and into the discharge pipe. Then, the cleaning scraper, which is fixedly connected to the rotating rod, cleans the surface of the sieve layer. At the same time, the cleaned drug particles can move towards the inner wall of the tank due to the arc design of the cleaning scraper, and then enter the discharge pipe through the discharge port 1. Finally, the drug particles screened by the sieve layer will be discharged through the discharge port on the lower surface of the tank. Attached Figure Description

[0019] To more clearly illustrate the technical solutions of the embodiments of this utility model, the drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. Among them:

[0020] Figure 1 This is a three-dimensional structural schematic diagram of a capsule particle screening device for the production of sustained-release tolterodine tartrate proposed in this utility model.

[0021] Figure 2 for Figure 1 A schematic diagram of the three-dimensional structure cross-section;

[0022] Figure 3 for Figure 2 Enlarged schematic diagram of the structure at point A in the middle;

[0023] Figure 4 This is a schematic diagram of the three-dimensional structure of the limiting ring.

[0024] In the diagram: 100, main unit; 101, tank; 102, discharge pipe; 103, screening layer; 200, screening unit; 201, slow-speed motor; 202, rotating rod; 203, feed pipe; 204, horizontal pipe; 205, retention plate; 206, transmission assembly; 206a, bevel gear; 206b, external gear ring; 207, fixing rod; 208, upper scraper; 209, connecting rod; 210, lower scraper; 211, cleaning scraper; 212, limiting ring. Detailed Implementation

[0025] To make the above-mentioned objectives, features and advantages of this utility model more apparent and understandable, the specific embodiments of this utility model will be described in detail below with reference to the accompanying drawings.

[0026] Many specific details are set forth in the following description in order to provide a full understanding of the present invention. However, the present invention may also be implemented in other ways different from those described herein. Those skilled in the art can make similar extensions without departing from the spirit of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0027] Secondly, the term "an embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The phrase "in one embodiment" appearing in different places in this specification does not necessarily refer to the same embodiment, nor is it a single or selective embodiment that excludes other embodiments.

[0028] Secondly, this utility model is described in detail with reference to the schematic diagrams. When describing the embodiments of this utility model, for ease of explanation, the cross-sectional views illustrating the device structure may be partially enlarged, not adhering to the usual scale. Furthermore, the schematic diagrams are merely examples and should not limit the scope of protection of this utility model. In addition, actual manufacturing should include the three-dimensional spatial dimensions of length, width, and depth.

[0029] Reference Figure 1 -4. This utility model provides a capsule particle screening device for the production of tolterodine tartrate sustained-release, comprising:

[0030] The main unit 100 includes a tank 101. A discharge pipe 102 is installed on one side of the tank 101. A sieve layer 103 is fixedly connected to the inner wall surface of the tank 101. A discharge port is opened on the lower surface of the tank 101. A discharge port 1 that cooperates with the sieve layer 103 is opened on one side of the tank 101, and the discharge port 1 is connected to the discharge pipe 102. A suction device is installed on one side of the discharge pipe 102, which is the prior art.

[0031] The screening unit 200 includes a slow-speed motor 201 fixedly connected to the lower surface of the tank 101. A rotating rod 202 is fixedly connected to the output shaft of the slow-speed motor 201. The surface of the rotating rod 202 is rotatably connected to the screening layer 103. A feed pipe 203 is fixedly connected to the upper end of the rotating rod 202 and is rotatably connected to the tank 101. A horizontal pipe 204 is rotatably connected to one side of the feed pipe 203, and a retention plate 205 is provided on the lower side of the horizontal pipe 204. One side of the 05 is fixedly connected to the inner wall surface of the tank 101. The surface of the retention plate 205 is provided with a transmission component 206. One side of the tank 101 is provided with a discharge port 2 that cooperates with the retention plate 205, and the discharge port 2 is connected to the discharge pipe 102. The surface of the horizontal pipe 204 is evenly provided with discharge holes, so that the feed pipe 203 drives the horizontal pipe 204 to rotate and evenly distribute the drug particles. Drug particles that cannot pass through the discharge holes will flow from the other end of the horizontal pipe 204 to the retention plate 205.

[0032] The transmission assembly 206 includes a bevel gear 206a fixedly connected to the outer surface of the horizontal tube 204, and an external toothed ring 206b meshing with one side surface of the bevel gear 206a. The lower surface of the external toothed ring 206b is fixedly connected to the retention plate 205, which can drive the horizontal tube 204 to rotate by rotating, so that the drug particles tumble inside the horizontal tube 204.

[0033] Furthermore, a fixing rod 207 is fixedly connected to the inner wall surface of the feed pipe 203, and an upper scraper 208 is fixedly connected to the upper surface of the fixing rod 207. The upper surface of the upper scraper 208 is movably connected to the inner wall surface of the horizontal pipe 204, and the upper scraper 208 cleans the drug particles adsorbed on the inner wall of the horizontal pipe 204.

[0034] Furthermore, a connecting rod 209 is fixedly connected to the lower surface of the fixed rod 207, and a lower scraper 210 is fixedly connected to the lower end of the connecting rod 209. The surface of the lower scraper 210 is slidably connected to the inner wall surface of the retention plate 205. The lower scraper 210 can rotate synchronously with the feed pipe 203 to push the drug particles inside the retention plate 205 toward the discharge port 2.

[0035] Furthermore, a cleaning scraper 211 is fixedly connected to one side surface of the rotating rod 202, and the lower surface of the cleaning scraper 211 is rotatably connected to the sieve layer 103. The cleaning scraper 211 has an arc-shaped design to clean the surface of the sieve layer 103. At the same time, the cleaned drug particles can move towards the inner wall of the tank 101 along the arc-shaped design of the cleaning scraper 211.

[0036] Furthermore, a limiting ring 212 is fixedly connected to the outer surface of the horizontal tube 204, and the surface of the limiting ring 212 is rotatably connected to the feed tube 203, thus having a limiting function.

[0037] During use, when the drug particles enter the horizontal tube 204 through the feed pipe 203, the slow-speed motor 201 is started by the power supply to drive the rotating rod 202 to rotate. The feed pipe 203, which is fixedly connected to the rotating rod 202, rotates inside the tank 101, causing the horizontal tube 204, which is rotatably connected to the feed pipe 203, to rotate inside the tank 101. This allows the drug particles to be evenly distributed on the surface of the sieve layer 103 through the initial screening of the horizontal tube 204 for secondary screening. Drug particles that cannot be screened by the horizontal tube 204 will slide into the retention plate 205 through the other end of the horizontal tube 204 and will not be retained inside the horizontal tube 204. At the same time, the external toothed ring 206b, which is fixedly connected to the retention plate 205, drives the meshing bevel gear 206a to rotate, causing the horizontal tube 204, which is fixedly connected to the bevel gear 206a, to rotate while rotating, thereby causing the horizontal tube 204 to rotate. The drug particles inside the 04 can roll and slide evenly. The fixed rod 207, which is fixedly connected to the feed pipe 203, drives the upper scraper 208 to scrape the inner wall surface of the horizontal pipe 204, so that the drug particles will not be retained inside the horizontal pipe 204. The connecting rod 209, which is fixedly connected to the fixed rod 207, drives the lower scraper 210 to slide on the inner wall surface of the retention plate 205, pushing the drug particles inside the lower scraper 210 towards the discharge port 2 and into the discharge pipe 102. Then, the cleaning scraper 211, which is fixedly connected to the rotating rod 202, cleans the surface of the sieve layer 103. At the same time, the cleaned drug particles can move towards the inner wall of the tank 101 along the arc design of the cleaning scraper 211, and then enter the discharge pipe 102 through the discharge port 1. Finally, the drug particles screened by the sieve layer 103 will be discharged through the discharge port on the lower surface of the tank 101.

[0038] It should be noted that the above embodiments are only used to illustrate the technical solution of this utility model and are not intended to limit it. Although this utility model has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solution of this utility model without departing from the spirit and scope of the technical solution of this utility model, and all such modifications or substitutions should be covered within the scope of the claims of this utility model.

Claims

1. A capsule granule screening device for the production of tolterodine tartrate sustained-release, characterized in that: include: The main unit (100) includes a tank (101), a discharge pipe (102) is installed on one side of the tank (101), a sieve layer (103) is fixedly connected to the inner wall surface of the tank (101), and a discharge port is opened on the lower surface of the tank (101). The screening unit (200) includes a slow motor (201) fixedly connected to the lower surface of the tank (101), and a rotating rod (202) fixedly connected to the output end of the slow motor (201). The surface of the rotating rod (202) is rotatably connected to the screening layer (103). The upper end of the rotating rod (202) is fixedly connected to a feed pipe (203), and the feed pipe (203) is rotatably connected to the tank (101). A horizontal pipe (204) is rotatably connected to one side of the feed pipe (203), and a retention plate (205) is provided on the lower side of the horizontal pipe (204). One side of the retention plate (205) is fixedly connected to the inner wall surface of the tank (101), and a transmission assembly (206) is provided on the surface of the retention plate (205). The transmission assembly (206) includes a bevel gear (206a) fixedly connected to the outer surface of the horizontal tube (204), and an external gear ring (206b) is meshed on one side surface of the bevel gear (206a), and the lower surface of the external gear ring (206b) is fixedly connected to the retention plate (205).

2. The capsule particle screening device for the production of tolterodine tartrate sustained-release according to claim 1, characterized in that: A fixing rod (207) is fixedly connected to the inner wall surface of the feed pipe (203), and an upper scraper (208) is fixedly connected to the upper side surface of the fixing rod (207). The upper side surface of the upper scraper (208) is movably connected to the inner wall surface of the horizontal pipe (204).

3. The capsule particle screening device for the production of tolterodine tartrate sustained-release according to claim 2, characterized in that: A connecting rod (209) is fixedly connected to the lower surface of the fixed rod (207), and a lower scraper (210) is fixedly connected to the lower end of the connecting rod (209). The surface of the lower scraper (210) is slidably connected to the inner wall surface of the retention plate (205).

4. The capsule particle screening device for the production of tolterodine tartrate sustained-release according to claim 3, characterized in that: A cleaning scraper (211) is fixedly connected to one side surface of the rotating rod (202), and the lower surface of the cleaning scraper (211) is rotatably connected to the sieve layer (103). The cleaning scraper (211) has an arc-shaped design.

5. The capsule particle screening device for the production of tolterodine tartrate sustained-release according to claim 4, characterized in that: The outer surface of the horizontal tube (204) is fixedly connected to a limiting ring (212), and the surface of the limiting ring (212) is rotatably connected to the feed tube (203).

Citation Information

Patent Citations

  • Capsule particle screening device

    CN220311000U