Intelligent stem cell transport box
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- YUNNAN NEW LIFE STEM CELL CO LTD
- Filing Date
- 2025-08-29
- Publication Date
- 2026-08-07
AI Technical Summary
[0003]干细胞在运输时需要进行冷藏,目前运输箱通常配备压缩系统或半导体制冷器来实现对干细胞的冷藏,但是通过单一的冷却系统进行冷藏,温度不够稳定,容易受外界影响而波动较大,温度波动易引发冰晶生长或细胞脱水,导致膜破裂,且能耗较高,同时目前现有的干细胞运输箱内部空间单一,不能合理利用来存放更多的干细胞,因此提出一种新的干细胞智能运输箱
[0015]1、本实用新型干细胞智能运输箱采用相变材料层和半导体制冷器两种方式,单一的半导体制冷器需持续工作维持低温,功耗高;而相变材料层在温度稳定时可储存冷量,半导体制冷器仅在温度偏移时启动补冷,大大降低能耗,同时确保了温度的稳定性。
Smart Images

Figure CN224603545U_ABST
Abstract
Description
Technical Field
[0001] This application relates to the field of stem cell transport technology, and in particular to a smart stem cell transport box. Background Technology
[0002] Stem cells are a type of pluripotent cell with the ability to self-replicate. Under certain conditions, they can differentiate into various functional cells. Based on their developmental stage, stem cells are divided into embryonic stem cells and adult stem cells. Based on their developmental potential, stem cells are divided into three categories: totipotent stem cells, pluripotent stem cells, and unipotent stem cells (multipotent stem cells). Stem cells are undifferentiated and immature cells with the potential to regenerate various tissues, organs, and the human body. They are known in the medical field as "universal cells".
[0003] Stem cells need to be refrigerated during transportation. Currently, transport boxes are usually equipped with compression systems or semiconductor refrigerators to refrigerate stem cells. However, refrigeration through a single cooling system is not stable enough and is easily affected by external factors, resulting in large fluctuations. Temperature fluctuations can easily cause ice crystal growth or cell dehydration, leading to membrane rupture, and the energy consumption is high. At the same time, the internal space of existing stem cell transport boxes is limited and cannot be used efficiently to store more stem cells. Therefore, a new intelligent stem cell transport box is proposed. Utility Model Content
[0004] To address the problems mentioned in the background art, this application provides a smart stem cell transport box.
[0005] The stem cell intelligent transport box provided in this application adopts the following technical solution:
[0006] A stem cell intelligent transport box includes a box body with a lid on top. A partition is fixed inside the box body, dividing the interior into a stem cell storage chamber and an air circulation chamber. The stem cell storage chamber contains at least two longitudinally arranged stem cell tube storage racks. Detachable components are fixed to both ends of each stem cell tube storage rack and are connected to the inner wall of the stem cell storage chamber. A semiconductor cooler is embedded in the top of the lid and is located directly above the air circulation chamber.
[0007] The enclosure comprises an outer shell layer, an insulation layer, and a phase change material layer from the outside to the inside. A temperature control module and a GPS module are embedded between the outer shell layer and the insulation layer.
[0008] Preferably, the outer shell layer is made of aerospace-grade aluminum alloy, the insulation layer is a vacuum insulation board, and the phase change material layer includes a stainless steel layer, the stainless steel layer being filled with metal-based PCM.
[0009] Preferably, the cold end of the semiconductor cooler is equipped with a circulating fan via a mounting bracket, the bottom side wall of the partition has a flow opening, and a gap of 3-5cm is provided between the partition and the top of the housing.
[0010] Preferably, the surface of the stem cell test tube storage rack has multiple through-holes.
[0011] Preferably, the detachable components are disposed at both symmetrical ends of the stem cell test tube storage rack, with two at each end. The detachable components include a housing fixed to the top lower surface of the stem cell test tube storage rack, a spring fixed inside the housing, and a rod connected to the spring. One end of the rod is inserted into a groove on the side wall of the stem cell storage cavity.
[0012] Preferably, both ends of the stem cell test tube storage rack are provided with a lever plate, the top of the shell is provided with a strip-shaped opening communicating with the top of the stem cell test tube storage rack, and a connecting plate is fixed to the surface of the insertion rod, the connecting plate being connected to the lever plate.
[0013] Preferably, the temperature of the phase change material layer is 5-10°C higher than the cold end of the semiconductor cooler.
[0014] Beneficial effects:
[0015] 1. The stem cell intelligent transport box of this utility model adopts two methods: phase change material layer and semiconductor cooler. A single semiconductor cooler needs to work continuously to maintain low temperature, which consumes a lot of power; while the phase change material layer can store cold energy when the temperature is stable, and the semiconductor cooler only starts to supplement cooling when the temperature deviates, which greatly reduces energy consumption and ensures temperature stability.
[0016] 2. This utility model optimizes the internal space of the box by setting up a detachable stem cell test tube storage rack. The stem cell test tube storage rack can be arranged vertically inside the box, so that the internal space can be used in a reasonable way. Attached Figure Description
[0017] Figure 1 This is a three-dimensional view of a stem cell intelligent transport box according to this application;
[0018] Figure 2 This is a perspective view of a stem cell intelligent transport box according to this application without its protective cover;
[0019] Figure 3 This is a perspective view of a stem cell intelligent transport box according to this application, without the protective cover and grounding rod.
[0020] Figure 4 This application relates to a stem cell intelligent transport box. Figure 2 Enlarged image;
[0021] Figure 5This application relates to a stem cell intelligent transport box. Figure 2 Enlarged image.
[0022] Explanation of reference numerals in the attached drawings: 1. Box body; 101. Outer shell layer; 102. Insulation layer; 103. Phase change material layer; 11. Stem cell storage chamber; 12. Air circulation chamber; 2. Box lid; 3. Semiconductor cooler; 4. Partition; 5. Stem cell test tube storage rack; 51. Through-hole; 6. Detachable component; 61. Shell; 62. Spring; 63. Insert rod; 64. Strip-shaped opening; 65. Connecting plate; 7. Mounting bracket; 8. Circulating fan; 9. Dial plate. Detailed Implementation
[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0024] Example
[0025] like Figures 1-5As shown, this application discloses a stem cell intelligent transport box, including a box body 1, a box cover 2 on the top of the box body 1, and a partition 4 fixed inside the box body 1, dividing the interior of the box body 1 into a stem cell storage chamber 11 and an air circulation chamber 12. The stem cell storage chamber 11 is equipped with at least two longitudinally arranged stem cell test tube racks 5, each with a different size of test tube placement hole on its surface, allowing for the placement of stem cell test tubes of different capacities. Detachable components 6 are fixed to both ends of each stem cell test tube rack 5, connecting to the inner wall of the stem cell storage chamber 11, thus facilitating the removal or placement of the stem cell test tube rack 5 as a whole inside the box body 1. In contrast, existing box bodies 1 are empty units, which hinders the efficient use of internal space. During transportation, the test tubes are easily shaken by bumps. A semiconductor cooler 3 is embedded in the top of the box cover 2. The semiconductor cooler 3 is located directly above the air circulation cavity 12. The box body 1 includes an outer shell layer 101, an insulation layer 102, and a phase change material layer 103 from the outside to the inside. A temperature control module and a GPS module are embedded between the outer shell layer 101 and the insulation layer 102. The temperature control module uses a programmable STM32F4 series MCU. At the same time, a temperature sensor array (PT1000 platinum resistance, ±0.1℃ accuracy) is also set inside the box body 1 to monitor the temperature in real time. The semiconductor cooler 3 is connected to the temperature control module through a circuit (the circuit is not shown in the figure). A power supply compartment is set at the bottom of the box body 1 for power supply. The battery uses a lithium thionyl chloride battery pack, which can store power for 720 hours, which is convenient for long-distance transportation.
[0026] The outer shell layer 101 is made of aerospace-grade aluminum alloy, which has strong impact resistance. The insulation layer 102 is a vacuum insulation board, which has good heat insulation effect and prevents heat loss. At the same time, the lid 2 is also composed of the outer shell layer 101 and the insulation layer 102 of the same material, which can prevent heat loss. The phase change material layer 103 includes a stainless steel layer, which is filled with metal-based PCM. It can absorb latent heat of phase change at a phase change temperature of 10~30℃. It also has high thermal conductivity (≈30 W / (m·K)) and fluidity, making it suitable for use with the semiconductor cooler 3.
[0027] The cold end of the semiconductor cooler 3 is equipped with a circulating fan 8 via a mounting bracket 7. A flow port is provided on the bottom side wall of the partition 4. A gap of 3-5cm is provided between the partition 4 and the top of the box 1. The circulating fan 8 can transport the air from the cold end of the semiconductor cooler 3 to the bottom of the stem cell storage chamber 11 through the flow port. Multiple through holes 51 are provided on the surface of the stem cell test tube storage rack 5. Then, the cold air passes through the multiple through holes 51 and flows back through the gap between the partition 4 and the top of the box 1 to complete the circulation, so that all parts inside the box 1 can be cooled evenly.
[0028] Detachable components 6 are located at both symmetrical ends of the stem cell tube storage rack 5, with two at each end. Each detachable component 6 includes a housing 61 fixed to the top lower surface of the stem cell tube storage rack 5. A spring 62 is fixed inside the housing 61, and the spring 62 is connected to an insertion rod 63. One end of the insertion rod 63 is inserted into a slot on the side wall of the stem cell storage cavity 11. Figure 1 As can be seen, an installation plate is provided on the inner wall of the stem cell storage cavity 11, and the groove is opened on the surface of the installation plate to avoid affecting the phase change material layer 103. At the same time, the installation plate can be made of a material with good thermal conductivity to facilitate cooling.
[0029] Both ends of the stem cell test tube storage rack 5 are equipped with levers 9. The top of the housing 61 is provided with a strip-shaped opening 64 that communicates with the top of the stem cell test tube storage rack 5. A connecting plate 65 is fixed to the surface of the insertion rod 63. The connecting plate 65 is connected to the levers 9. When it is necessary to take out the stem cell test tube storage rack 5, it is only necessary to move the two levers 9 to move the insertion rod 63 towards the spring 62, thereby disengaging the insertion rod 63 from the slot. Then, by lifting the two levers 9, the stem cell test tube storage rack 5 with stem cell test tubes can be taken out from the inside of the housing 1.
[0030] The temperature of the phase change material layer 103 is 5-10°C higher than that of the cold end of the semiconductor cooler 3. When the temperature is stable, the phase change material layer 103 can store cold energy. The semiconductor cooler 3 only starts to supplement cooling when the temperature deviates, which greatly reduces energy consumption and ensures temperature stability. When the temperature inside the chamber 1 is too low and below the preset value, the semiconductor cooler 3 is turned off, and the temperature stability is ensured by the phase change material layer 103. When the temperature inside the chamber 1 deviates and the temperature is higher than the preset value, the semiconductor cooler 3 and the phase change material layer 103 continue to store cold energy.
[0031] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely preferred examples and are not intended to limit the utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.
Claims
1. A stem cell intelligent transport box, comprising a box body (1), wherein a box cover (2) is provided on the top of the box body (1), characterized in that: The box (1) is fixed with a partition (4) inside, which divides the interior of the box (1) into a stem cell storage chamber (11) and an air circulation chamber (12). The stem cell storage chamber (11) is provided with at least two longitudinally arranged stem cell test tube storage racks (5). The two ends of the stem cell test tube storage racks (5) are respectively fixed with detachable components (6). The detachable components (6) are connected to the inner wall of the stem cell storage chamber (11). The top of the box cover (2) is embedded with a semiconductor cooler (3). The semiconductor cooler (3) is located directly above the air circulation chamber (12). The enclosure (1) includes an outer shell layer (101), an insulation layer (102), and a phase change material layer (103) from the outside to the inside. A temperature control module and a GPS module are embedded between the outer shell layer (101) and the insulation layer (102).
2. The intelligent stem cell transport box according to claim 1, characterized in that: The outer shell layer (101) is made of aerospace-grade aluminum alloy, the insulation layer (102) is a vacuum insulation board, and the phase change material layer (103) includes a stainless steel layer, the stainless steel layer being filled with metal-based PCM.
3. The intelligent stem cell transport box according to claim 1, characterized in that: The cold end of the semiconductor cooler (3) is equipped with a circulating fan (8) via a mounting bracket (7). The bottom side wall of the partition (4) has a flow port. A gap of 3-5cm is provided between the partition (4) and the top of the box (1).
4. The intelligent stem cell transport box according to claim 3, characterized in that: The surface of the stem cell test tube storage rack (5) has multiple through-holes (51).
5. A stem cell intelligent transport box according to claim 1, characterized in that: The detachable components (6) are located at the symmetrical ends of the stem cell test tube storage rack (5), and there are two at each end. The detachable components (6) include a housing (61) fixed to the top lower surface of the stem cell test tube storage rack (5). A spring (62) is fixed inside the housing (61). The spring (62) is connected to a rod (63). One end of the rod (63) is inserted into the slot on the side wall of the stem cell storage cavity (11).
6. A stem cell intelligent transport box according to claim 5, characterized in that: Both ends of the stem cell test tube storage rack (5) are provided with a lever (9), the top of the shell (61) is provided with a strip-shaped opening (64) that communicates with the top of the stem cell test tube storage rack (5), and a connecting plate (65) is fixed on the surface of the insertion rod (63), and the connecting plate (65) is connected to the lever (9).
7. A stem cell intelligent transport box according to claim 1, characterized in that: The temperature of the phase change material layer (103) is 5-10°C higher than that of the cold end of the semiconductor cooler (3).