Nucleic acid detection cartridge and nucleic acid detection instrument

Abstract

The utility model provides a nucleic acid detection box and nucleic acid detection instrument, include: piston pipe is provided with the piston cavity of containing liftable pipette piston, detection reagent pipe includes big pipe section and is connected with small pipe section lower extreme little pipe section, big pipe section is provided with the upper cavity, small pipe section is provided with the lower cavity of containing freeze -drying reagent, the cross section size of upper cavity is greater than the cross section size of small pipe section, the bottom of small pipe section is provided with pipette mouth, and the first pipette flow channel of being able to lead through or seal is arranged between piston pipe and pipette mouth, and pipette mouth is used for the solution in piston pipe to enter lower cavity, isolation piston, from upper cavity and with lower cavity sealed cooperation, the cavity wall of upper cavity and isolation piston form the containing space between, and the containing space is used for containing desiccant particle or sealing liquid. The utility model can realize internal pipetting and completely eliminate external environmental interference by plugging the top and bottom of freeze -drying reagent.

Description

Technical Field

[0001] This utility model belongs to the field of testing equipment technology, and in particular relates to a nucleic acid detection kit and a nucleic acid detection instrument. Background Technology

[0002] Nucleic acids are the carriers of genetic information in living organisms and are essential components of all known life forms. There are two main types of nucleic acids: DNA and RNA, which are primarily found in the cell nucleus and exist in a state bound to proteins. With the rapid development of molecular biology, the research and analysis of nucleic acids are increasingly being promoted and applied in fields such as clinical diagnosis, food safety, environmental monitoring, and agriculture, forestry, and animal husbandry.

[0003] In the current field of molecular diagnostics, semi-closed reagent chamber structures are generally used to store liquid reagents. Due to the significant convenience of lyophilized reagents in storage and transportation, their application has become increasingly widespread. However, lyophilized reagents are susceptible to external environmental interference and can become ineffective. Existing reagent chamber structures cannot completely eliminate external environmental interference, potentially leading to low detection accuracy. Furthermore, the widespread application of lyophilized reagents will place new demands on the pressure balance of solid-liquid reagent mixing, which existing reagent chamber structures cannot meet. Utility Model Content

[0004] The main purpose of this invention is to propose a nucleic acid detection kit and a nucleic acid detection instrument, which aims to solve the technical problem that the reagent chamber structure in the prior art cannot completely eliminate interference from the external environment.

[0005] To achieve the above objectives, this utility model provides a nucleic acid detection kit, comprising: a piston tube with a piston cavity for accommodating a liftable pipette piston; a detection reagent tube comprising a large tube segment and a small tube segment connected to the lower end of the large tube segment, the large tube segment having an upper cavity, and the small tube segment having a lower cavity for accommodating lyophilized reagents, the cross-sectional dimension of the upper cavity being larger than that of the small tube segment, and a pipetting port being provided at the bottom of the small tube segment; a first pipetting channel that can be opened or sealed is provided between the piston tube and the pipetting port, the pipetting port being used to allow the solution in the piston tube to enter the lower cavity; and an isolation piston extending from the upper cavity into the lower cavity and sealingly engaging with the lower cavity, a receiving space being formed between the cavity wall of the upper cavity and the isolation piston, the receiving space being used to accommodate desiccant particles or sealing liquid.

[0006] In this embodiment of the invention, an exhaust channel is provided on the side wall of the small pipe segment. The exhaust channel extends downward from the top of the small pipe segment and is used to connect the upper cavity and the lower cavity.

[0007] In this embodiment of the invention, the number of exhaust channels is at least two, and the at least two exhaust channels are arranged at circumferential intervals along the small pipe segment.

[0008] In this embodiment of the invention, the nucleic acid detection kit further includes a detection chamber, and the number of pipettes is two. One pipette allows the solution in the piston tube to enter the lower cavity. A second pipette channel that can be opened or sealed is provided between the detection chamber and the pipette. The other pipette allows the solution in the lower cavity to enter the detection chamber.

[0009] In this embodiment of the invention, the number of detection chambers is at least two, and the number of detection reagent tubes is the same as the number of detection chambers and they are arranged in a one-to-one correspondence.

[0010] In this embodiment of the invention, any two adjacent test reagent tubes are connected by a planar partition, and the isolation piston is provided with a piston plane that slides in cooperation with the planar partition.

[0011] In this embodiment of the utility model, the isolation piston includes: a push head; a main body, the upper end of which is connected to the push head, the cross-sectional dimension of which is larger than that of the main body; and a sealing post, connected to the lower end of the main body, the sealing post being used for sealing cooperation with the lower cavity.

[0012] In this embodiment of the utility model, the sealing column is provided with a plurality of sealing protrusions, at least two of the sealing protrusions are arranged sequentially in the vertical direction, and an exhaust groove is formed between any two adjacent sealing protrusions; and / or, the sealing column is provided with a plurality of reinforcing ribs.

[0013] In this embodiment of the present invention, the nucleic acid detection kit further includes: a sample tube having a sample cavity for accommodating the sample; and a plurality of pretreatment tubes located between the sample tube and the piston tube, wherein the pretreatment tubes have a pretreatment cavity for pretreatment of the sample, and both the sample tube and the pretreatment tubes are used to connect to or isolate the piston tube.

[0014] This utility model also proposes a nucleic acid detection instrument, which includes a nucleic acid detection module and a nucleic acid detection box as described above.

[0015] Through the above technical solution, the nucleic acid detection kit provided by this utility model embodiment has the following beneficial effects:

[0016] The nucleic acid testing kit features a stepped cross-section with a larger upper chamber and a smaller lower chamber. The larger upper chamber allows for easy assembly of the isolation piston while simultaneously accommodating gas, meeting the pressure balance requirements for mixing solid and liquid reagents. The isolation piston at the top seals and isolates the lyophilized reagents in the lower chamber, while desiccant particles between the piston and the larger tube further seal the lower chamber. This double isolation of the lyophilized reagents, combined with the piston, prevents external environmental interference and ensures the bottom of the kit remains sealed. The device features a first pipetting channel that can be opened or sealed. This sealed channel can block the bottom of the lyophilized reagent, effectively preventing external interference. When transferring the solution from the piston chamber to the lower chamber, the first pipetting channel can be opened, and the piston can be pressed down. This allows the solution in the piston chamber to pass sequentially through the first pipetting channel and the pipetting port into the lower chamber, completing the solution transfer and solid-liquid mixing within the nucleic acid detection kit. This eliminates the need for external pipetting components found in existing technologies, further preventing external interference. In this embodiment, the nucleic acid detection kit uses a top-larger, bottom-smaller structure for the test reagent tube. The top of the lyophilized reagent is sealed in layers by an isolating piston, and the bottom features a first pipetting channel that can be opened or sealed, blocking both the top and bottom ends of the lyophilized reagent. This allows for internal pipetting while completely preventing external interference and avoiding reagent failure.

[0017] Other features and advantages of this invention will be described in detail in the following detailed description section. Attached Figure Description

[0018] The accompanying drawings are provided to illustrate the present invention and form part of the specification. They are used together with the following detailed description to explain the present invention, but do not constitute a limitation thereof. In the drawings:

[0019] Figure 1 This is a schematic diagram of the structure of a nucleic acid detection box according to an embodiment of the present invention;

[0020] Figure 2 This is a schematic diagram of the cross-sectional structure of a nucleic acid detection box according to an embodiment of the present invention;

[0021] Figure 3 This is a partial structural cross-sectional schematic diagram of a nucleic acid detection box according to an embodiment of the present invention;

[0022] Figure 4 This is a partial structural cross-sectional schematic diagram of the nucleic acid detection box according to another embodiment of the present invention;

[0023] Figure 5This is a schematic diagram of the isolation piston structure of a nucleic acid detection box according to an embodiment of the present invention.

[0024] Explanation of reference numerals in the attached figures

[0025] Detailed Implementation

[0026] The specific embodiments of this utility model will be described in detail below with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are for illustration and explanation only and are not intended to limit the scope of this utility model.

[0027] The nucleic acid detection kit according to this utility model is described below with reference to the accompanying drawings.

[0028] like Figures 1 to 5 As shown in the embodiment of this utility model, the nucleic acid detection kit 100 includes a piston tube 1, a detection reagent tube 2, and an isolation piston 3. The piston tube 1 is provided with a piston cavity to accommodate a liftable pipette piston. The detection reagent tube 2 includes a large tube section 21 and a small tube section 23 connected to the lower end of the large tube section 21. The large tube section 21 is provided with an upper cavity 22, and the small tube section 23 is provided with a lower cavity 24 to accommodate lyophilized reagents. A pipette port 27 is provided at the bottom of the small tube section 23. A first pipette channel 8 that can be opened or sealed is provided between the piston tube 1 and the pipette port 27. The pipette port 27 is used to allow the solution in the piston tube 1 to enter the lower cavity 24. The isolation piston 3 extends from the upper cavity 22 into the lower cavity 24 and is sealed with the lower cavity 24. A receiving space is formed between the cavity wall of the upper cavity 22 and the isolation piston 3. The receiving space is used to accommodate desiccant particles 4 or sealing liquid.

[0029] Understandably, the nucleic acid detection kit 100 in this embodiment can be a one-piece molded part, the piston tube 1 and the detection reagent tube 2 can be one-piece molded, and the isolation piston 3, drying reagent and lyophilized reagent can be pre-placed in the nucleic acid detection kit 100.

[0030] In one embodiment, the top of the test reagent tube 2 is open, and a closable cap is provided at the top of the test reagent tube 2. The test reagent tube 2 can be opened or closed by opening and closing the cap, facilitating sealing and opening of the test reagent tube 2. The cap can be integrally formed into the test reagent tube 2. The size and quantity of the desiccant particles 4 in this embodiment can be set according to actual usage requirements. It should be noted that the pipette piston can be moved up and down relative to the piston tube 1 under external force, and the isolating piston 3 can also be moved up and down relative to the test reagent tube 2 under external force. Figure 3 As shown, the bottom of the nucleic acid test kit 100 has a valve column cavity for the pipetting valve column to extend into. The valve column cavity extends in the left and right direction. A pipetting groove can be provided on the pipetting valve column to connect the pipetting port 27 and the first pipetting channel 8. The first pipetting channel 8 and the pipetting port 27 can be sealed or connected through the pipetting valve column.

[0031] In this embodiment, the nucleic acid detection kit 100 features a stepped cross-section with the test reagent tube 2 designed to be larger at the top and smaller at the bottom. The upper cavity 22 has a larger cross-sectional size, facilitating the assembly of the isolation piston 3 while simultaneously accommodating gas. This meets the pressure balance requirements for mixing solid and liquid reagents. Furthermore, while the isolation piston 3 seals and isolates the lyophilized reagent in the lower cavity 24, the desiccant particles 4 or sealing liquid filled between the isolation piston 3 and the large tube section 21 further seal the lower cavity 24. The desiccant particles 4 or sealing liquid, combined with the isolation piston 3, provide double isolation to the top of the lyophilized reagent, preventing external contamination of the nucleic acid detection kit 100. To prevent environmental interference, the bottom of the lyophilized reagent is equipped with a first pipetting channel 8 that can be opened or sealed. The bottom of the lyophilized reagent can be sealed by the first pipetting channel 8, thus sealing both the top and bottom ends of the lyophilized reagent and effectively preventing interference from the external environment. When it is necessary to transfer the solution in the piston chamber to the lower chamber 24, the first pipetting channel 8 can be opened and the pipetting piston can be pressed down, so that the solution in the piston chamber can pass through the first pipetting channel 8 and the pipetting port 27 in sequence and enter the lower chamber 24, completing the solution transfer and solid-liquid mixing inside the nucleic acid detection box 100. There is no need to use the external pipetting components in the existing technology, which can further prevent interference from the external environment. In this embodiment, the nucleic acid detection kit 100 has a structure where the detection reagent tube 2 is larger at the top and smaller at the bottom. The top of the lyophilized reagent can be sealed in layers by the isolation piston 3, and a first pipetting channel 8 that can be opened or sealed is set at the bottom. By sealing the top and bottom ends of the lyophilized reagent, internal pipetting can be achieved while completely eliminating external environmental interference and avoiding the failure of the lyophilized reagent.

[0032] In one embodiment, an exhaust channel 25 is provided on the side wall of the small tube segment 23. The exhaust channel 25 extends downward from the top of the small tube segment 23 and connects the upper cavity 22 and the lower cavity 24. In this embodiment, the exhaust channel 25 is elongated, with its top flush with the top of the small tube segment 23 and its bottom higher than the bottom of the small tube segment 23. During solid-liquid mixing, gas is discharged from the lower cavity 24 through the exhaust channel 25, and the isolation piston 3 can be lowered to a position that completely seals the lower cavity 24. The bottom of the isolation piston 3 is lower than the bottom of the exhaust channel 25. In this embodiment, the gas in the lower cavity 24 is discharged through the exhaust channel 25, which can meet the requirement of gas pressure balance between the piston tube 1 and the test reagent tube 2.

[0033] In another embodiment, the containment space contains a sealed liquid, which is a liquid reaction reagent. During the process of the isolation piston 3 being pressed down, when the bottom of the isolation piston 3 is lower than the bottom of the exhaust channel 25, the upper cavity 22 can be connected to the lower cavity 24 through the exhaust channel 25. The liquid reaction reagent can flow into the freeze-dried reagent cavity through the exhaust channel 25 to form a detection reaction system, and balance the air pressure of the upper and lower cavities of the isolation piston 3 through the exhaust channel 25.

[0034] Specifically, there are at least two exhaust channels 25, which are arranged at circumferential intervals along the small tube segment 23. The number of exhaust channels 25 can be set according to actual usage requirements. In one embodiment, there are two exhaust channels 25 in each test reagent tube 2, which are arranged opposite each other in the front-back direction to improve the efficiency of air pressure balance.

[0035] like Figure 3 and Figure 4 As shown, the nucleic acid detection kit 100 also includes a detection chamber 5 and two pipette ports 27. One pipette port 27 allows the solution in the piston tube 1 to enter the lower chamber 24. A second pipette channel 9, which can be opened or sealed, is provided between the detection chamber 5 and the pipette port 27. The other pipette port 27 allows the solution in the lower chamber 24 to enter the detection chamber 5. The test reagent tube 2 is located between the piston tube 1 and the detection chamber 5 in the front-to-back direction. In this embodiment, the bottom of the lower chamber 24 has a downwardly protruding conical surface. One pipette port 27 is located at the bottom of the conical surface, and the other pipette port 27 is higher than the bottom of the conical surface. The pipette port 27 located at the bottom can be connected to the detection chamber 5 through the second pipette channel 9, which can ensure that the solution is fully transferred to the detection chamber 5 through the pipette port 27. In this embodiment, the isolation piston 3 can not only seal the top of the lyophilized reagent, but also push down the mixed liquid in the cavity 24 by external force. With the pipette port 27 and the second pipette channel 9 connected, the mixed solution of the lyophilized reagent can enter the detection chamber 5 under the squeezing action of the isolation piston 3. The detection chamber 5 is matched with the nucleic acid detection module of the nucleic acid detector (which can be an existing PCR module), and can cooperate with the nucleic acid detector to perform nucleic acid detection.

[0036] In one embodiment, the number of detection chambers 5 is at least two, and the number of detection reagent tubes 2 and detection chambers 5 are the same and correspond one-to-one. The number of detection chambers 5 can be set according to actual usage requirements. At least two detection chambers 5 can be spaced apart along the width direction (i.e., left-right direction) of the nucleic acid detection kit 100, and at least two detection reagent tubes 2 can be set along the left-right direction. In this embodiment, by pre-filling different lyophilized reagents in different detection reagent tubes 2, multiplex nucleic acid detection can be achieved through one nucleic acid detection kit 100, resulting in high detection efficiency.

[0037] It should be noted that any two adjacent test reagent tubes 2 are connected by a flat partition 26, and the isolation piston 3 is provided with a piston surface 31 that slides and engages with the flat partition 26. When the isolation piston 3 is pressed down by an external force, the piston surface 31 of the isolation piston 3 can slide and engage with the flat partition 26, which can ensure the smoothness of the downward pressing of the isolation piston 3.

[0038] like Figure 5 As shown, the isolation piston 3 includes a push head 32, a main body 33, and a sealing column 34. The upper end of the main body 33 is connected to the push head 32, and the cross-sectional dimension of the push head 32 is larger than that of the main body 33. The sealing column 34 is connected to the lower end of the main body 33 and is used for sealing with the lower cavity 24. In this embodiment, the isolation piston 3 has a three-section structure. The top of the push head 32 can be provided with a positioning groove to facilitate the positioning of the driving component. Both the push head 32 and the main body 33 are columnar, which is convenient for production. The sealing column 34 is located at the bottom of the main body 33. The cross-sectional dimensions of both the push head 32 and the sealing column 34 are larger than those of the main body 33, which facilitates the filling of desiccant particles 4. In this embodiment, the push head 32 can be made of a flexible material, which facilitates the interference fit between the push head 32 and the lower cavity 24.

[0039] In one embodiment, the sealing column 34 is provided with a plurality of sealing protrusions 35, which are arranged sequentially in the vertical direction, and an exhaust groove 36 is formed between any two adjacent sealing protrusions 35; and the sealing column 34 is provided with a plurality of reinforcing ribs. In another embodiment, the sealing column 34 is provided with three sealing protrusions 35 from top to bottom, and an exhaust groove 36 is formed between any two adjacent sealing protrusions 35. During the solid-liquid mixing process, gas can enter the exhaust channel 25 through the exhaust groove 36 and then enter the upper cavity 22 through the exhaust channel 25, which can further ensure the gas pressure balance during the solid-liquid mixing process.

[0040] In this embodiment of the invention, the nucleic acid detection kit 100 further includes a sample tube 6 and multiple pretreatment tubes 7. The sample tube 6 is provided with a sample cavity for containing the sample. The multiple pretreatment tubes 7 are located between the sample tube 6 and the piston tube 1. The pretreatment tubes 7 are provided with a pretreatment cavity for sample pretreatment. The sample tube 6 and the pretreatment tubes 7 are used to connect or isolate the piston tube 1. In this embodiment, the sample tube 6, the pretreatment tube 7 and the piston tube 1 are arranged sequentially along the length of the nucleic acid detection kit 100 (i.e., the front-to-back direction). The multiple pretreatment tubes 7, from back to front, can be used as an ultrasonic tube for ultrasound, a first washing tube for containing washing solution, a second washing tube for containing washing solution, a magnetic bead tube for containing magnetic beads, a protease tube for containing protease, a first elution tube for containing elution solution, a second elution tube for containing elution solution, and a lysis tube for lysis. In this embodiment, the pretreatment tubes 7 and the detection reagent tube 2 are isolated by the piston tube 1, which facilitates the pretreatment of the sample. Both the sample tube 6 and the pretreatment tube 7 have valve column cavities at their bottoms to accommodate the pipetting valve column. The connection or isolation between the sample tube 6 and the piston tube 1, and between the pretreatment tube 7 and the piston tube 1, can be achieved by moving the pipetting valve column. In other embodiments, the connection or isolation between the sample tube 6 and the piston tube 1, and between the pretreatment tube 7 and the piston tube 1, can adopt other structural forms.

[0041] This utility model also proposes a nucleic acid detection instrument, which includes a nucleic acid detection module and a nucleic acid detection box 100 as described above. The specific structure of the nucleic acid detection box 100 is as described in the above embodiments. Since the nucleic acid detection instrument adopts all the technical solutions of all the above embodiments, it has at least all the beneficial effects brought about by the technical solutions of the above embodiments, which will not be elaborated here.

[0042] In the description of this utility model, it should be understood that the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this utility model, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0043] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection, an electrical connection, or a connection that allows communication between them; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise explicitly limited. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0044] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0045] Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention. Those skilled in the art can make changes, modifications, substitutions and variations to the above embodiments within the scope of the present invention.

Claims

1. A nucleic acid detection kit, characterized in that, The nucleic acid detection kit (100) includes: The piston tube (1) is provided with a piston chamber to accommodate a liftable pipetting piston; The test reagent tube (2) includes a large tube section (21) and a small tube section (23) connected to the lower end of the large tube section (21). The large tube section (21) is provided with an upper cavity (22), and the small tube section (23) is provided with a lower cavity (24) for containing lyophilized reagents. The cross-sectional dimension of the upper cavity (22) is larger than that of the small tube section (23). The bottom of the small tube section (23) is provided with a pipette port (27). A first pipette channel (8) that can be opened or sealed is provided between the piston tube (1) and the pipette port (27). The pipette port (27) is used to allow the solution in the piston tube (1) to enter the lower cavity (24). An isolation piston (3) extends from the upper cavity (22) into the lower cavity (24) and is sealed to the lower cavity (24). A receiving space is formed between the cavity wall of the upper cavity (22) and the isolation piston (3). The receiving space is used to receive desiccant particles (4) or sealing liquid.

2. The nucleic acid detection kit according to claim 1, characterized in that, The side wall of the small tube segment (23) is provided with an exhaust channel (25), which extends downward from the top of the small tube segment (23) and is used to connect the upper cavity (22) and the lower cavity (24).

3. The nucleic acid detection kit according to claim 2, characterized in that, The number of exhaust channels (25) is at least two, and at least two exhaust channels (25) are arranged at circumferential intervals along the small pipe segment (23).

4. The nucleic acid detection kit according to any one of claims 1 to 3, characterized in that, The nucleic acid detection kit (100) also includes a detection chamber (5), and there are two pipette ports (27). One pipette port (27) allows the solution in the piston tube (1) to enter the lower cavity (24). A second pipette channel (9) that can be opened or sealed is provided between the detection chamber (5) and the pipette port (27). The other pipette port (27) allows the solution in the lower cavity (24) to enter the detection chamber (5).

5. The nucleic acid detection kit according to claim 4, characterized in that, The number of the detection chambers (5) is at least two, and the number of the test reagent tubes (2) and the number of the detection chambers (5) are the same and are set in a one-to-one correspondence.

6. The nucleic acid detection kit according to claim 5, characterized in that, Any two adjacent test reagent tubes (2) are connected by a planar partition (26), and the isolation piston (3) is provided with a piston plane (31) that slides with the planar partition (26).

7. The nucleic acid detection kit according to any one of claims 1 to 3, characterized in that, The isolation piston (3) includes: Push head (32); The main body (33) is connected to the upper end of the push head (32), and the cross-sectional dimension of the push head (32) is larger than that of the main body (33); A sealing post (34) is connected to the lower end of the main body (33), and the sealing post (34) is used to seal with the lower cavity (24).

8. The nucleic acid detection kit according to claim 7, characterized in that, The sealing column (34) is provided with a plurality of sealing protrusions (35), at least two of the sealing protrusions (35) are arranged sequentially in the vertical direction, and an exhaust groove (36) is formed between any two adjacent sealing protrusions (35). And / or, The sealing column (34) is provided with multiple reinforcing ribs.

9. The nucleic acid detection kit according to any one of claims 1 to 3, characterized in that, The nucleic acid testing kit (100) also includes: The sample tube (6) is provided with a sample cavity to hold the sample; Multiple pretreatment tubes (7) are located between the sample tube (6) and the piston tube (1). The pretreatment tube (7) is provided with a pretreatment cavity for sample pretreatment. The sample tube (6) and the pretreatment tube (7) are used to connect or disconnect the piston tube (1).

10. A nucleic acid detection instrument, characterized in that, The nucleic acid testing instrument includes a nucleic acid testing module and a nucleic acid testing kit (100) as described in any one of claims 1 to 9.

Images