A feeding device for a fermentation material

CN224604956UActive Publication Date: 2026-08-07NEW TUOYANG BIO-ENG CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
NEW TUOYANG BIO-ENG CO LTD
Filing Date
2025-09-08
Publication Date
2026-08-07

AI Technical Summary

Technical Problem

而原有发酵设备已相对固定,需要的种液或抗生素用量与设备不够匹配,也不适用进行火焰接种的方法

Benefits of technology

[0014]本实用新型采用补料瓶,装入菌液、抗生素溶液等物料,并通过设计的补料管路将物料泵入发酵罐中,解决目前已有发酵设备的补料问题。该补料装置分为可拆的几部分,便于对各部件进行灭菌处理操作。该补料装置,还可扩展,比如增加隔膜阀的数量,改变补料瓶所装入的物料类型。

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Abstract

The utility model relates to a kind of material supplementing device for fermentation, including first double braid diaphragm valve, second double braid diaphragm valve, single braid diaphragm valve, first double braid diaphragm valve includes first diaphragm valve, first sub valve, second sub valve, and first diaphragm valve is connected to the material supplementing mouth of fermentation tank by first material pipe;First sub valve is connected with first steam inlet pipe, and second sub valve is connected with steam outlet pipe;Second double braid diaphragm valve includes second diaphragm valve, third sub valve, fourth sub valve, third sub valve is connected with second steam inlet pipe, and fourth sub valve is connected to first material supplementing bottle by second material pipe, and first peristaltic pump is connected on second material pipe;Single braid diaphragm valve, including third diaphragm valve, fifth sub valve, and fifth sub valve is connected to second material supplementing bottle by third material pipe. Adopt material supplementing bottle to load into bacteria liquid, antibiotic solution, and material is pumped into fermentation tank by the material supplementing pipeline designed, solve the material supplementing problem of existing fermentation equipment.
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Description

Technical Field

[0001] This utility model relates to the field of fermentation equipment technology, specifically to a feeding device for fermentation materials. Background Technology

[0002] In production processes primarily using E. coli fermentation, various situations arise during fermentation, such as the need for inoculation or antibiotic supplementation. However, existing fermentation equipment is relatively fixed, and the required amounts of inoculum or antibiotics are not well-matched to the equipment, nor is flame inoculation a suitable method. Therefore, it is necessary to design a feed-in device specifically to meet the needs of actual production. Utility Model Content

[0003] The purpose of this invention is to provide a feeding device for fermentation materials to address the feeding needs existing in the prior art.

[0004] To achieve the above objectives, the present invention adopts the following technical solution:

[0005] A feeding device for fermentation materials includes a first double-braided diaphragm valve, a second double-braided diaphragm valve, and a single-braided diaphragm valve that are detachably connected in sequence via pipes. The first double-braided diaphragm valve includes a first diaphragm valve, a first sub-valve, and a second sub-valve. The first diaphragm valve is connected to the feeding port of the fermenter via a first feed pipe. A first steam inlet pipe is connected to the first sub-valve, and a steam outlet pipe is connected to the second sub-valve.

[0006] The second double-braided diaphragm valve includes a second diaphragm valve, a third sub-valve, and a fourth sub-valve. The third sub-valve is connected to a second steam inlet pipe, and the fourth sub-valve is connected to a first feed bottle through a second feed pipe. A first peristaltic pump is connected to the second feed pipe.

[0007] The single-braid diaphragm valve includes a third diaphragm valve and a fifth sub-valve. The fifth sub-valve is connected to the second feed bottle through a third feed pipe. A second peristaltic pump is connected to the third feed pipe.

[0008] Furthermore, the first diaphragm valve and the second diaphragm valve are connected by a fourth feed pipe, and the second diaphragm valve and the third diaphragm valve are connected by a fifth feed pipe. Both the fourth and fifth feed pipes are equipped with chucks for docking.

[0009] Furthermore, both the first and second replenishment bottles are connected to an exhaust pipe, and the exhaust pipe is covered with a breathable structural layer.

[0010] Furthermore, the first sub-valve and the second sub-valve are arranged side by side, and the third sub-valve and the fourth sub-valve are arranged side by side.

[0011] Furthermore, the feeding device has a first sterilization mode, in which the first diaphragm valve is closed, the first sub-valve is open, and the first steam inlet pipe is used to introduce steam for a set duration.

[0012] Furthermore, the feeding device has a second sterilization mode, in which the first diaphragm valve and the second diaphragm valve are closed, the second sub-valve is open, and the second steam inlet pipe is used to introduce steam for a set duration.

[0013] The beneficial effects of this utility model are:

[0014] This invention employs a feeding bottle to hold materials such as bacterial solution and antibiotic solution, and pumps these materials into the fermenter through a designed feeding pipeline, solving the feeding problem of existing fermentation equipment. The feeding device consists of several detachable parts, facilitating sterilization of each component. This feeding device can also be expanded, for example, by increasing the number of diaphragm valves or changing the type of material contained in the feeding bottle. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the application state of a feeding device for fermentation materials according to this utility model;

[0016] Figure 2 This is a schematic diagram showing the connection of the components of a feeding device for fermentation materials according to this utility model.

[0017] 1. Fermentation tank; 2. First double-braided diaphragm valve; 21. First sub-valve; 22. Second sub-valve; 3. Second double-braided diaphragm valve; 31. Third sub-valve; 32. Fourth sub-valve; 4. Single-braided diaphragm valve; 41. Fifth sub-valve; 51. First feed bottle; 52. Second feed bottle; 61. First chuck; 62. Second chuck; 63. Third chuck; 71. First peristaltic pump; 72. Second peristaltic pump; 8. Exhaust pipe; 91. First feed pipe; 92. Second feed pipe; 93. Third feed pipe. Detailed Implementation

[0018] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art are within the protection scope of the present utility model.

[0019] Embodiments of this utility model:

[0020] like Figures 1-2As shown, a feeding device for fermentation materials includes a first double-braided diaphragm valve 2, a second double-braided diaphragm valve 3, and a single-braided diaphragm valve 4, which are detachably connected in sequence via pipes. The first double-braided diaphragm valve 2 includes a first diaphragm valve, a first sub-valve 21, and a second sub-valve 22. The first diaphragm valve is connected to the feeding port of the fermenter 1 via a first feed pipe 91. The principle of the diaphragm valve is existing technology; essentially, it is a valve that controls the flow of fluid. The first diaphragm valve is the main valve, and the first sub-valve 21 and the second sub-valve 22 are small valves arranged in parallel. They can be connected to different pipelines. The first sub-valve 21 and the second sub-valve 22 can be opened and closed independently, resembling two small braids, hence the name double-braided diaphragm valve. This valve structure also exists in existing technology; it is simply being applied here.

[0021] The first sub-valve 21 is connected to the first steam inlet pipe, which is used for sterilization before the equipment is used. It can be connected to an external steam pipe to introduce high-temperature steam. The steam is externally connected.

[0022] Similarly, the second double-braided diaphragm valve 3 includes a second diaphragm valve, a third sub-valve 31, and a fourth sub-valve 32. A second steam inlet pipe is connected to the third sub-valve 31, and the fourth sub-valve 32 is connected to the first feed bottle 51 via a second feed pipe 92. In this embodiment, the first feed bottle 51 is defined as being used to hold the bacterial solution. A first peristaltic pump 71 is connected to the second feed pipe 92, which pumps the bacterial solution into the fermenter 1 during feeding. The third sub-valve 31 and the fourth sub-valve 32 are arranged side-by-side.

[0023] The second sub-valve 22 is connected to a steam exhaust pipe, which is used during sterilization before the equipment is used. It can be used to exhaust the high-temperature steam introduced from upstream, so as to realize the flow of steam in the corresponding pipeline.

[0024] The single-braid diaphragm valve 4 includes a third diaphragm valve and a fifth sub-valve 41. The fifth sub-valve 41 is connected to the second feed bottle 52 through the third feed pipe 93. In this embodiment, the second feed bottle 52 is defined as being used to hold antibiotic solution. In other embodiments, it can also be selected as needed, such as inducer, liquid alkali, etc.

[0025] The third feed pipe 93 is connected to a second peristaltic pump 72, which pumps the antibiotic solution into the fermenter 1 when feeding.

[0026] The first and second diaphragm valves are connected via a fourth feed pipe, and the second and third diaphragm valves are connected via a fifth feed pipe. Both the fourth and fifth feed pipes are equipped with a first chuck 61 and a second chuck 62 for docking. This can be understood as the fourth and fifth feed pipes being two-sectioned. Using a chuck-type silicone hose allows for quick docking of the two pipes. This chuck-type quick-connect structure is existing technology.

[0027] Both the first feed bottle 51 and the second feed bottle 52 are connected to an exhaust pipe 8, and the exhaust port of the exhaust pipe 8 is covered with a breathable structural layer. The breathable structural layer is made of multiple layers of gauze and an outermost layer of kraft paper, tightly wrapped with cotton thread, which allows air to pass through while preventing bacteria from entering.

[0028] The feeding device has a first sterilization mode, in which the first diaphragm valve is closed, the first sub-valve 21 is open, and the first steam inlet pipe is used to introduce steam for a set duration. The feeding device also has a second sterilization mode, in which the first and second diaphragm valves are closed, the second sub-valve 22 is open, and the second steam inlet pipe is used to introduce steam for a set duration.

[0029] The principle of the feeding device for fermentation materials of this utility model:

[0030] When sterilizing fermenter 1, close the first diaphragm valve, open the first sub-valve 21, and introduce high-temperature steam. After sterilization is completed, close the first sub-valve 21 to achieve sterilization of zone A.

[0031] For components in zones B and C (excluding the peristaltic pump), sterilization is performed in an autoclave. The second and third diaphragm valves are tightened and closed, the third sub-valve 31 is closed, and the fourth sub-valve 32 and the fifth sub-valve 41 are slightly open. The exhaust pipes 8 of the first and second feed bottles are permeable but prevent bacteria from entering, facilitating the sterilization of the entire component. After sterilization, once cooled to room temperature, the fourth sub-valve 32 and the fifth sub-valve 41 are closed. In a clean bench, the bacterial solution is loaded into the first feed bottle 51, and the antibiotics are loaded into the second feed bottle 52.

[0032] Connect the first chuck 61, the steam pipe is connected to the second steam inlet pipe through the third chuck 63, the third sub-valve 31 is opened, steam enters from the third sub-valve 31 and exits from the second sub-valve 22, sterilizing area B, or the boundary between areas A and B.

[0033] After sterilization is completed, an external peristaltic pump is used to pump the bacterial solution or antibiotics into fermenter 1; the principle of the peristaltic pump is existing technology and does not come into direct contact with the liquid being transported.

Claims

1. A feeding device for fermentation materials, characterized in that: It includes a first double-braided diaphragm valve, a second double-braided diaphragm valve, and a single-braided diaphragm valve that are detachably connected by pipes in sequence. The first double-braided diaphragm valve includes a first diaphragm valve, a first sub-valve, and a second sub-valve. The first diaphragm valve is connected to the feed port of the fermenter through a first feed pipe. A first steam inlet pipe is connected to the first sub-valve, and a steam outlet pipe is connected to the second sub-valve. The second double-braided diaphragm valve includes a second diaphragm valve, a third sub-valve, and a fourth sub-valve. The third sub-valve is connected to a second steam inlet pipe, and the fourth sub-valve is connected to a first feed bottle through a second feed pipe. A first peristaltic pump is connected to the second feed pipe. The single-braid diaphragm valve includes a third diaphragm valve and a fifth sub-valve. The fifth sub-valve is connected to the second feed bottle through a third feed pipe. A second peristaltic pump is connected to the third feed pipe.

2. The feeding device for fermentation materials according to claim 1, characterized in that: The first diaphragm valve and the second diaphragm valve are connected by a fourth feed pipe, and the second diaphragm valve and the third diaphragm valve are connected by a fifth feed pipe. Both the fourth and fifth feed pipes are equipped with chucks for docking.

3. The feeding device for fermentation materials according to claim 1, characterized in that: Both the first and second feed bottles are connected to an exhaust pipe, which is covered with a breathable structural layer.

4. The feeding device for fermentation materials according to claim 1, characterized in that: The first sub-valve and the second sub-valve are arranged side by side, and the third sub-valve and the fourth sub-valve are arranged side by side.

5. The feeding device for fermentation materials according to claim 1, characterized in that: The feeding device has a first sterilization mode, with the first diaphragm valve closed, the first sub-valve open, and the first steam inlet pipe used to introduce steam for a set duration.

6. The feeding device for fermentation materials according to claim 1, characterized in that: The feeding device has a second sterilization mode, in which the first diaphragm valve and the second diaphragm valve are closed, the second sub-valve is open, and the second steam inlet pipe is used to introduce steam for a set duration.