A stirring type drying apparatus for pharmaceutical products
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- KANGYING CRANBERRY (ZHONGSHAN) BIOPHARMACEUTICAL CO LTD
- Filing Date
- 2025-09-02
- Publication Date
- 2026-08-07
AI Technical Summary
[0004]本申请所要解决的一个技术问题是:现有的医药生产设备缺乏精准的温度监控与调控机制,容易因加热过度导致热敏性药品的有效成分被破坏,进而造成药效降低,以及药品受热不均,无法满足热敏性药品干燥对低温、精准控温的需求的问题
1.本实用新型在使用时,在热敏性药品干燥安全性与药效保障上,温度检测装置、真空装置及加热元件的配合发挥核心作用。壳体内壁的加热元件(如夹套加热)可直接对内腔加热,使药品水分受热蒸发;温度检测装置延伸至壳体内腔,能实时监控温度,精准规避高温导致的热敏性药品(如生物制剂、维生素类、中药活性成分)有效成分破坏(如蛋白质变性、黄酮类分解)、药效降低,以及物料变色(如中药浸膏发黑)、结块等问题;真空装置同样延伸至内腔,可将腔体抽至负压,降低水的沸点,从根本上避免高温对热敏成分的破坏,双重保障了热敏性药品干燥后的质量与药效。
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Figure CN224608049U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of pharmaceutical production technology, specifically to a stirring-type drying device for pharmaceuticals. Background Technology
[0002] Stirred drying equipment for pharmaceuticals is a specialized piece of equipment used in the pharmaceutical manufacturing industry for drying pharmaceutical products. This equipment uses a stirring structure to ensure uniform heating of the pharmaceuticals, and combined with temperature control and a vacuum system, it removes moisture from the pharmaceuticals while maintaining their quality. It is particularly suitable for drying heat-sensitive pharmaceuticals, providing support for moisture control and efficacy retention in the pharmaceutical production process. It is widely used in the production of biological agents, vitamins, and traditional Chinese medicine preparations.
[0003] Traditional stirred-type drying equipment for pharmaceuticals has significant shortcomings in the drying of heat-sensitive drugs. Most equipment lacks precise temperature monitoring and control mechanisms, failing to monitor temperature changes within the shell cavity in real time. This makes them prone to overheating, which can damage the active ingredients in heat-sensitive drugs, leading to protein denaturation, flavonoid decomposition, and ultimately reduced efficacy. Furthermore, existing equipment often uses atmospheric pressure heating, requiring relatively high temperatures to achieve moisture evaporation. This inherently makes it difficult to avoid damage to heat-sensitive components and may cause discoloration, clumping, and other quality issues. In addition, some equipment has poorly designed heating structures, resulting in uneven heating and further increasing the risk of localized damage to active ingredients. These systems cannot meet the low-temperature, precise temperature control requirements for drying heat-sensitive drugs, making it difficult to guarantee the quality and efficacy of the dried drugs. Therefore, we propose a stirred-type drying device for pharmaceuticals. Utility Model Content
[0004] One of the technical problems this application aims to solve is that existing pharmaceutical production equipment lacks a precise temperature monitoring and control mechanism, which can easily lead to the destruction of the effective components of heat-sensitive drugs due to overheating, resulting in reduced efficacy and uneven heating of the drugs, thus failing to meet the requirements of low temperature and precise temperature control for drying heat-sensitive drugs.
[0005] To address the aforementioned technical problems, this application provides a stirring-type drying device for pharmaceuticals, comprising a housing, a temperature detection device fixedly connected to one outer wall of the upper end of the housing, a vacuum device fixedly connected to one outer wall of the upper end of the housing, an upper gate plate fixedly connected to one outer wall of the upper end of the housing, a lower gate plate fixedly connected to one outer wall of the lower end of the housing, a discharge pipe fixedly connected to the bottom end of the housing, a motor fixedly connected to the middle of the upper outer wall of the housing, a rotating rod connected to the lower end of the motor, and a combined stirring paddle fixedly connected to one outer wall of the rotating rod.
[0006] In some embodiments, a fixed bracket is fixedly connected to the lower outer wall of one side of the housing, an exhaust pipe is connected to the outer wall of one side of the housing, multiple limiting blocks are fixedly connected to both sides of the inner wall of the exhaust pipe, a filter screen is movably connected to both sides of the inner wall of the exhaust pipe, a limiting groove is formed on the outer wall of the filter screen, and an exhaust device is connected to the side of the exhaust pipe away from the housing.
[0007] In some embodiments, the limiting groove on the outer wall of the filter screen is correspondingly connected to the limiting block provided on one side of the inner wall of the exhaust pipe.
[0008] In some embodiments, the housing is connected to the exhaust device via an exhaust pipe.
[0009] In some embodiments, the temperature detection device and the vacuum device are respectively located on the upper two sides of the housing, and their bottoms extend to one side of the inner wall of the housing.
[0010] In some embodiments, the rotating rod and the combined stirring paddle at the lower end of the motor are both located in the middle of one side of the inner wall of the housing, and the combined stirring paddle is in contact with one side of the inner wall of the housing.
[0011] In some embodiments, the lower ends of the temperature detection device and the vacuum device are located near the upper end of the combined stirring paddle.
[0012] In some embodiments, the upper gate and the lower gate both extend to one side of the inner wall of the housing and are connected to the side close to the combined agitator.
[0013] This utility model has at least the following beneficial effects: 1. In use, the temperature detection device, vacuum device, and heating element work together to ensure the safety and efficacy of drying heat-sensitive drugs. The heating element (such as jacket heating) on the inner wall of the shell can directly heat the inner cavity, causing the moisture in the drug to evaporate. The temperature detection device extends into the inner cavity of the shell, enabling real-time temperature monitoring and precise avoidance of problems such as damage to the effective components of heat-sensitive drugs (such as biological agents, vitamins, and active ingredients of traditional Chinese medicine) caused by high temperatures (e.g., protein denaturation, flavonoid decomposition), reduced efficacy, discoloration of materials (e.g., blackening of traditional Chinese medicine extracts), and clumping. The vacuum device also extends into the inner cavity, which can draw the cavity to negative pressure, lowering the boiling point of water and fundamentally avoiding damage to heat-sensitive components by high temperatures. This dual protection ensures the quality and efficacy of the dried heat-sensitive drugs.
[0014] 2. In use, this utility model demonstrates outstanding performance in terms of the configuration of the upper gate, lower gate, exhaust device, and filter screen in terms of drying process stability and dust control. The alternating opening and closing of the upper and lower gate effectively avoids pressure fluctuations between the cavity and downstream equipment during unloading, preventing dust from flying. The induced draft fan in the exhaust device extracts the humid air from the evaporated medicine, and the condenser assists in processing the humid steam, ensuring a stable drying environment. The filter screen on the inner wall of the exhaust pipe traps dust, preventing medicine loss. Simultaneously, the limiting block on the inner wall of the exhaust pipe corresponds to the limiting groove on the outer wall of the filter screen, providing a stable and limiting function for the filter screen, preventing it from shifting or tilting and causing trapping failure, further ensuring the stability of the drying process and the medicine recovery rate.
[0015] 3. In use, this utility model exhibits significant advantages in terms of comprehensive material handling and anti-sticking effect due to the design of the motor, rotating rod, and combined stirring paddle. The motor drives the rotating rod to rotate the combined stirring paddle (ribbon + anchor type). The stirring paddle adheres to the inner wall of the shell and covers the entire cavity, which not only guides the material to flow evenly and ensures consistent heating, but also scrapes away sticky materials adhering to the wall in real time, preventing material from sticking to the wall, charring, or being wasted, thus improving the comprehensiveness of material handling and drying efficiency. Attached Figure Description
[0016] Figure 1 This is a first-person perspective schematic diagram of the overall structure of this utility model; Figure 2 This is a schematic diagram of the overall structure of the present invention from a second perspective; Figure 3 This is a schematic diagram of the internal disassembly structure of the housing of this utility model; Figure 4 This is a cross-sectional disassembly diagram of the exhaust pipe of this utility model.
[0017] In the diagram: 1. Shell; 2. Fixed bracket; 3. Temperature detection device; 4. Vacuum device; 5. Upper gate; 6. Lower gate; 7. Discharge pipe; 8. Motor; 9. Rotating rod; 10. Combined stirring paddle; 11. Exhaust pipe; 12. Limiting block; 13. Filter screen; 14. Limiting groove; 15. Exhaust device. Detailed Implementation
[0018] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0019] Example 1: Please refer to Figure 1-3This utility model provides a technical solution: a stirring-type drying device for pharmaceuticals, comprising a shell 1, a temperature detection device 3 fixedly connected to one outer wall of the upper end of the shell 1, a vacuum device 4 fixedly connected to one outer wall of the upper end of the shell 1, the temperature detection device 3 and the vacuum device 4 respectively located on both sides of the upper end of the shell 1, and both extending to one side of the inner wall of the shell 1 at their bottom, an upper gate 5 fixedly connected to one outer wall of the upper end of the shell 1, a lower gate 6 fixedly connected to one side of the lower end of the shell 1, and a discharge pipe 7 fixedly connected to the bottom end of the shell 1. A motor 8 is fixedly connected to the middle of the upper outer wall of the housing 1. A rotating rod 9 is connected to the lower end of the motor 8. A combined stirring paddle 10 is fixedly connected to the outer wall of one side of the rotating rod 9. The rotating rod 9 and the combined stirring paddle 10 at the lower end of the motor 8 are both located in the middle of one side of the inner wall of the housing 1. The combined stirring paddle 10 is attached to one side of the inner wall of the housing 1. The lower ends of the temperature detection device 3 and the vacuum device 4 are close to the upper end of the combined stirring paddle 10. The upper gate 5 and the lower gate 6 extend to one side of the inner wall of the housing 1 and are connected to the side close to the combined stirring paddle 10.
[0020] In this embodiment, a shell 1 is designed, with a temperature detection device 3 and a vacuum device 4 connected to both sides of the upper outer wall of the shell 1. A heating element is provided on one side of the inner wall of the shell 1, which can directly heat the inner wall of the shell 1. This is existing technology, such as jacketed heating. By providing the temperature detection device 3 and the vacuum device 4, the lower ends of both the temperature detection device 3 and the vacuum device 4 can extend to one side of the inner wall of the shell 1. Furthermore, the temperature detection device 3 can monitor the temperature of the inner cavity of the shell 1 in real time, so that the moisture in the medicine evaporates into wet vapor when heated. By monitoring, it is possible to avoid the destruction of the effective components of heat-sensitive drugs (such as biological agents, vitamins, and active ingredients of traditional Chinese medicine) (such as protein denaturation, decomposition of flavonoids), reduced efficacy, and situations that may cause material discoloration (such as blackening of traditional Chinese medicine extracts) or clumping (affecting subsequent preparations). The process involves a vacuum device 4, which creates negative pressure within the cavity, lowering the boiling point of water and preventing high temperatures from damaging heat-sensitive components. An upper gate 5 and a lower gate 6 are installed at the upper and lower ends of the housing 1, respectively. The alternating opening and closing of these gates prevents pressure fluctuations and avoids dust dispersion caused by pressure differences between the cavity and downstream equipment during unloading. A motor 8 is fixedly connected to the middle of the upper outer wall of the housing 1, with a rotating rod 9 connected to its lower end. The rotating rod 9 extends to one side of the inner wall of the housing 1, and a combined stirring paddle 10 is fixedly connected to its outer wall. The combined stirring paddle 10 fits snugly against the inner wall of the housing 1. The combined stirring paddle 10 includes a spiral ribbon and an anchor type, covering the entire cavity and guiding material flow. For viscous materials, the rotation of the combined stirring paddle 10 can scrape away the adhering medicine in real time.
[0021] Example 2: Please refer to Figure 1-4A fixed bracket 2 is fixedly connected to the lower outer wall of one side of the housing 1. An exhaust pipe 11 is connected to the outer wall of one side of the housing 1. Multiple limiting blocks 12 are fixedly connected to both sides of the inner wall of the exhaust pipe 11. A filter screen 13 is movably connected to both sides of the inner wall of the exhaust pipe 11. A limiting groove 14 is opened on the outer wall of the filter screen 13. The limiting groove 14 opened on the outer wall of the filter screen 13 is correspondingly connected to the limiting block 12 provided on one side of the inner wall of the exhaust pipe 11. An exhaust device 15 is connected to the side of the exhaust pipe 11 away from the housing 1. The housing 1 and the exhaust device 15 are connected through the exhaust pipe 11.
[0022] In this embodiment, a fixed bracket 2 is fixedly connected to one side of the lower end of the housing 1. The fixed bracket 2 can provide fixed support for the housing 1. An exhaust device 15 is connected to one side of the outer wall of the housing 1 through an exhaust pipe 11. The exhaust device 15 includes an induced draft fan and a condenser to extract the humid air evaporated from the medicine. At the same time, a filter screen 13 is provided on both sides of the inner wall of the exhaust pipe 11 to trap dust. Three limiting grooves 14 are arranged in a ring on the outer wall of the filter screen 13, and three limiting blocks 12 are arranged in a ring on both sides of the inner wall of the exhaust pipe 11. The limiting blocks 12 are connected to the limiting grooves 14 to connect and limit the filter screen 13, so as to prevent the filter screen 13 from shifting and tilting, which would prevent it from trapping dust and causing medicine loss.
[0023] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.
[0024] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention.
Claims
1. A stirring-type drying device for pharmaceuticals, comprising a housing (1), characterized in that: A temperature detection device (3) is fixedly connected to one side of the upper outer wall of the shell (1), a vacuum device (4) is fixedly connected to one side of the upper outer wall of the shell (1), an upper gate (5) is fixedly connected to one side of the upper outer wall of the shell (1), a lower gate (6) is fixedly connected to one side of the lower outer wall of the shell (1), a discharge pipe (7) is fixedly connected to the bottom of the shell (1), a motor (8) is fixedly connected to the middle of the upper outer wall of the shell (1), a rotating rod (9) is connected to the lower end of the motor (8), and a combined stirring paddle (10) is fixedly connected to one side of the outer wall of the rotating rod (9).
2. The stirring-type drying equipment for pharmaceuticals according to claim 1, characterized in that: A fixed bracket (2) is fixedly connected to the lower outer wall of one side of the housing (1). An exhaust pipe (11) is connected to the outer wall of one side of the housing (1). Multiple limiting blocks (12) are fixedly connected to both sides of the inner wall of the exhaust pipe (11). A filter screen (13) is movably connected to both sides of the inner wall of the exhaust pipe (11). A limiting groove (14) is opened on the outer wall of the filter screen (13). An exhaust device (15) is connected to the side of the exhaust pipe (11) away from the housing (1).
3. The stirring-type drying equipment for pharmaceuticals according to claim 2, characterized in that: The limiting groove (14) on the outer wall of the filter (13) is connected to the limiting block (12) on one side of the inner wall of the exhaust pipe (11).
4. A stirring-type drying device for pharmaceuticals according to claim 2, characterized in that: The housing (1) is connected to the exhaust device (15) via an exhaust pipe (11).
5. A stirring-type drying device for pharmaceuticals according to claim 1, characterized in that: The temperature detection device (3) and the vacuum device (4) are respectively located on the upper sides of the housing (1), and their bottoms extend to one side of the inner wall of the housing (1).
6. A stirring-type drying device for pharmaceuticals according to claim 1, characterized in that: The rotating rod (9) and the combined stirring paddle (10) at the lower end of the motor (8) are both located in the middle of one side of the inner wall of the shell (1), and the combined stirring paddle (10) is attached to one side of the inner wall of the shell (1).
7. A stirring-type drying device for pharmaceuticals according to claim 1, characterized in that: The lower ends of the temperature detection device (3) and the vacuum device (4) are close to the upper end of the combined stirring paddle (10).
8. A stirring-type drying device for pharmaceuticals according to claim 1, characterized in that: The upper gate (5) and the lower gate (6) both extend to one side of the inner wall of the housing (1) and are close to the side of the combined stirring paddle (10).