A body fluid cytology pull piece integrated processing device

Abstract

This utility model relates to an integrated sample preparation device for body fluid cytology, comprising a transparent glass container, a pre-fixation container, a reduced-pressure filtration structure, and a fixation container. The transparent glass container is internally divided into a regular filtration space and a reduced-pressure filtration space. The pre-fixation container is detachably mounted on the transparent glass container and contains a filter plate and a regular filtration structure for sample pre-fixation. The reduced-pressure filtration structure is detachably connected to the transparent glass container and communicates with the reduced-pressure filtration space. The fixation container is connected to the reduced-pressure filtration structure for secondary sample fixation. This device, through step-by-step pre-fixation and secondary fixation, combined with a dual filtration mechanism of regular and reduced-pressure filtration, achieves efficient recovery and reuse of the fixative, reduces reagent consumption, and avoids cross-contamination. This utility model is compact, easy to operate, and suitable for clinical body fluid cytology testing, significantly improving experimental efficiency and testing quality.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, specifically to an integrated processing device for body fluid cytology smears. Background Technology

[0002] In the cytopathological screening of body fluid samples (such as pleural effusion, cerebrospinal fluid, urine, and sputum), cells need to be separated from the fluid through centrifugation, and the cell pellet is then sliced ​​and fixed in a fixation container equipped with a staining rack. Common fixatives include 95% ethanol (15-30 min) and 10% neutral formalin (30-60 min). After the staining rack is full and fixation is complete, subsequent staining is performed as needed for diagnosis. However, in practice, body fluid cytology slices are usually placed directly into the fixation container with the staining rack for fixation. This results in a large amount of cell detachment forming in the fixative within a short time, easily leading to cross-contamination between different samples. Therefore, frequent changes of fixative are necessary, increasing experimental costs. To avoid cross-contamination and improve the utilization rate of fixative, designing a pre-fixation container for body fluid cytology slices that allows for the reuse of fixative and a filtration device has become an urgent technical challenge. Utility Model Content

[0003] This invention aims to solve the problems in the prior art where cell sediment falls into the fixative during fixation of body fluid cytology slides, easily leading to cross-contamination between different samples, and the frequent replacement of fixative increases experimental costs. Therefore, it provides an integrated processing device for body fluid cytology slides.

[0004] To solve the above-mentioned technical problems, the technical solution of this utility model is as follows:

[0005] An integrated sample preparation device for body fluid cytology includes a transparent glass container, a pre-fixation container detachably mounted on the transparent glass container, a depressurization filtration structure communicating with the interior of the transparent glass container, and a fixed container communicating with the depressurization filtration structure. The transparent glass container is divided into a normal filtration space and a depressurization filtration space. The pre-fixation container is provided with a filter plate and a normal filtration structure located below the filter plate. A glass partition is provided on the filter plate, and the glass partition divides the pre-fixation container into two sample placement spaces on the left and right sides. The pre-fixation container is suitable for pre-fixing samples, and the fixed container is suitable for secondary fixation of samples.

[0006] Furthermore, the transparent glass container is equipped with a pressure gauge that communicates with the interior of the pressure-reducing filtration space and a connection port for connecting a vacuum pump.

[0007] Furthermore, the fixed container is provided with an infusion tube that communicates with the pressure-reducing filtration structure, and the infusion tube is provided with a drive pump. The pressure-reducing filtration structure is a Buchner filter.

[0008] Furthermore, a through-conical filter is provided at the bottom of the pre-fixed container, and the filter plate is disposed inside the conical filter.

[0009] Furthermore, the conical filter is equipped with a stop valve.

[0010] Furthermore, the top of the transparent glass container has a first opening above the ordinary filtration space and a second opening above the depressurization filtration space. The ordinary filtration structure is detachably installed on the first opening, and the depressurization filtration structure is detachably installed on the second opening.

[0011] Furthermore, both the first opening and the second opening can be detachably fitted with knob sealing covers.

[0012] Furthermore, a glass partition is provided inside the transparent glass container, which divides the interior of the transparent glass container into the ordinary filtration space and the depressurization filtration space.

[0013] Furthermore, the bottom of the transparent glass container is provided with a first drain port and a second drain port. The first drain port is connected to the interior of the ordinary filtration space, and the second drain port is connected to the interior of the pressure-reducing filtration space.

[0014] Furthermore, the first discharge port is connected to a first discharge pipe located outside the glass container, and the first discharge pipe is equipped with a first discharge valve; the second discharge port is connected to a second discharge pipe located outside the glass container, and the second discharge pipe is equipped with a second discharge valve.

[0015] The technical solution of this utility model has the following advantages:

[0016] 1. The integrated body fluid cytology slide processing device provided by this utility model involves pre-fixation in a pre-fixation container, followed by secondary fixation in a fixed container. The fixative solution in the pre-fixation container, containing cell sediment, is filtered directly through a conventional filtration structure at its bottom after use. The fixative solution in the fixed container is filtered through a vacuum filtration structure after secondary fixation. The fixative solution in the fixed container flows to the fixed container after vacuum filtration. This device allows for the reuse of the fixative solution in the pre-fixation container after filtration during pre-fixation, and also allows for reuse of the fixative solution in the fixed container after filtration during secondary fixation. This efficient recovery of fixative reduces the overall usage and prevents cross-contamination between different samples, thereby improving experimental efficiency and quality.

[0017] 2. The integrated body fluid cytology smear processing device provided by this utility model has a pressure gauge and a connection port for connecting a vacuum pump on a transparent glass container that communicate with the interior of the reduced-pressure filtration space. This configuration allows for effective shortening of the filtration time during filtration operations when combined with vacuum pump decompression. The pressure gauge also allows operators to easily control the pressure within the reduced-pressure filtration space within a suitable range based on the boiling point of the fixative.

[0018] 3. The integrated body fluid cytology slide processing device provided by this utility model has an infusion tube connected to the pressure-reducing filtration structure on the fixed container, and a drive pump is installed on the infusion tube. The pressure-reducing filtration structure is a Buchner filter. This configuration allows the drive pump to automatically transport the fixative solution in the fixed container to the Buchner filter for filtration, avoiding manual handling, reducing labor intensity, and improving work efficiency.

[0019] 4. The integrated body fluid cytology slide processing device provided by this utility model has a stop valve on the conical filter. This design allows the stop valve to be opened directly after the fixative in the pre-fixation container is used up, allowing the fixative to flow into the ordinary filtration space without the need for personnel to repeatedly empty it, making operation simple and convenient. Attached Figure Description

[0020] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0021] Figure 1 A three-dimensional structural diagram of the integrated body fluid cytology smear processing device provided by this utility model;

[0022] Figure 2 A perspective view of the integrated body fluid cytology smear processing device provided by this utility model.

[0023] Explanation of reference numerals in the attached drawings: 1. Pre-fixed container; 2. Ordinary filtration space; 3. Pressure-reducing filtration space; 4. Conical filter; 5. Buchner filter; 6. Glass septum; 7. Support; 8. Glass partition; 9. First opening; 10. Second opening; 11. First sealing cap; 12. Second sealing cap; 13. Connection port; 14. Pressure gauge; 15. First drain pipe; 16. First drain valve; 17. Second drain pipe; 18. Second drain valve; 19. Transparent glass container; 20. Fixed container; 21. Infusion pipe; 22. Filter plate; 23. Check valve; 24. Drive pump. Detailed Implementation

[0024] The technical solution of this utility model will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0025] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0026] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0027] Furthermore, the technical features involved in the different embodiments of this utility model described below can be combined with each other as long as they do not conflict with each other.

[0028] like Figure 1 , Figure 2 The device shown is an integrated sample processing device for body fluid cytology, comprising a transparent glass container 19, a pre-fixed container 1 detachably mounted on the transparent glass container 19, a depressurization filtration structure communicating with the interior of the transparent glass container 19, and a fixed container 20 communicating with the depressurization filtration structure. The transparent glass container 19 is divided into a normal filtration space 2 and a depressurization filtration space 3. The pre-fixed container 1 is provided with a filter plate 22 and a normal filtration structure located below the filter plate 22. A glass partition 6 is provided on the filter plate 22, which divides the pre-fixed container 1 into two sample placement spaces on the left and right sides. The pre-fixed container 1 is suitable for pre-fixing samples, and the fixed container 20 is suitable for secondary fixation of samples.

[0029] This integrated fluid cytology slide processing device uses a pre-fixation container 1 for pre-fixation, followed by transfer to a fixation container 20 for secondary fixation. The fixative solution in the pre-fixation container 1, containing cell sediment, is filtered directly through a standard filtration structure at its bottom after use. The fixative solution in the fixation container 20 is filtered through a vacuum filtration structure after secondary fixation. The fixative solution in the fixation container 20 flows to the fixation container 20 after vacuum filtration. This device allows for the reuse of the fixative solution in the pre-fixation container 1 after filtration, and the fixative solution in the fixation container 20 after filtration, both for secondary fixation. This efficient recovery of fixative reduces overall usage and prevents cross-contamination between different samples, thereby improving experimental efficiency and quality.

[0030] In this embodiment, the filtration and recovery device further includes a support 7, on which the transparent glass filter is mounted. The top of the transparent glass container 19 has a first opening 9 above the ordinary filtration space 2 and a second opening 10 above the reduced-pressure filtration space 3. The ordinary filtration structure is detachably installed on the first opening 9, and the reduced-pressure filtration structure is detachably installed on the second opening 10. Specifically, a first sealing cap 11 is detachably installed on the first opening 9, and a second sealing cap 12 is detachably installed on the second opening 10. Both the first sealing cap 11 and the second sealing cap 12 are knob-type sealing caps. A glass partition 8 is provided inside the transparent glass container 19, dividing the interior of the transparent glass container 19 into the ordinary filtration space 2 and the reduced-pressure filtration space 3.

[0031] In this embodiment, the bottom of the transparent glass container 19 is provided with a first drain port and a second drain port. The first drain port is connected to the interior of the ordinary filtration space 2, and the second drain port is connected to the interior of the pressure-reducing filtration space 3. Specifically, a first drain pipe 15 located outside the glass container is connected to the first drain port, and a first drain valve 16 is provided on the first drain pipe 15; a second drain pipe 17 located outside the glass container is connected to the second drain port, and a second drain valve 18 is provided on the second drain pipe 17.

[0032] The transparent glass container 19 is equipped with a pressure gauge 14 that communicates with the interior of the vacuum filtration space 3 and a connection port 13 for connecting a vacuum pump. This configuration allows for effective reduction of filtration time during filtration operations when combined with a vacuum pump, and the pressure gauge 14 enables operators to easily control the pressure within the vacuum filtration space 3 within a suitable range based on the boiling point of the stationary liquid.

[0033] In this embodiment, the fixed container 20 is provided with an infusion pipe 21 that communicates with the pressure-reducing filtration structure. A drive pump 24 is provided on the infusion pipe 21, and the pressure-reducing filtration structure is a Buchner filter 5. With this configuration, when it is necessary to filter the stationary liquid in the fixed container 20, the drive pump can be used to transport the stationary liquid in the fixed container 20 to the Buchner filter 5 for filtration, eliminating the need for manual handling of the heavy fixed container 20, reducing labor intensity, and effectively improving work efficiency.

[0034] In this embodiment, a through-conical filter 4 is provided at the bottom of the pre-fixed container 1, and a filter plate 22 is disposed inside the conical filter 4. Specifically, a stop valve 23 is provided on the conical filter 4. This arrangement allows the stop valve 23 to be opened directly after the fixative in the pre-fixed container 1 has been used, allowing the fixative to flow into the ordinary filtration space 2 without the need for personnel to repeatedly pour it out, making the operation simple and convenient.

[0035] In this embodiment, both the pre-fixing container 1 and the fixing container 20 have graduation lines on their side walls. This design facilitates the operator in controlling the amount of fixing liquid poured in.

[0036] In summary, this integrated fluid cytology slide processing device uses a pre-fixation container 1 for pre-fixation, followed by transfer to a fixation container 20 for secondary fixation. The fixative solution in the pre-fixation container 1, containing cell sediment, is filtered directly through a standard filtration structure at its bottom after use. The fixative solution in the fixation container 20 is filtered through a reduced-pressure filtration structure after secondary fixation. The fixative solution in the fixation container 20 flows to the fixation container 20 after reduced-pressure filtration. This device allows for the reuse of the fixative solution in the pre-fixation container 1 after filtration during pre-fixation, and the fixative solution in the fixation container 20 can also be reused during secondary fixation after filtration. This efficient recovery of fixative reduces the overall usage and prevents cross-contamination between different samples, thereby improving experimental efficiency and quality.

[0037] Obviously, the above embodiments are merely illustrative examples for clear explanation and are not intended to limit the implementation. Those skilled in the art will recognize that other variations or modifications can be made based on the above description. It is neither necessary nor possible to exhaustively list all possible implementations here. However, obvious variations or modifications derived therefrom are still within the protection scope of this invention.

Claims

1. A body fluid cytology integrated smear processing device, characterized in that, The device includes a transparent glass container (19), a pre-fixed container (1) detachably mounted on the transparent glass container (19), a pressure-reducing filtration structure communicating with the interior of the transparent glass container (19), and a fixed container (20) communicating with the pressure-reducing filtration structure. The transparent glass container (19) is divided into a normal filtration space (2) and a pressure-reducing filtration space (3). The pre-fixed container (1) is provided with a filter plate (22) and a normal filtration structure located below the filter plate. A glass partition (6) is provided on the filter plate (22). The glass partition (6) divides the pre-fixed container (1) into two sample placement spaces on the left and right sides. The pre-fixed container (1) is suitable for pre-fixing the sample, and the fixed container (20) is suitable for secondary fixation of the sample.

2. The integrated body fluid cytology smear processing device according to claim 1, characterized in that, The transparent glass container (19) is provided with a pressure gauge (14) that communicates with the inside of the pressure-reducing filtration space (3) and a connection port (13) for connecting a vacuum pump.

3. The integrated body fluid cytology smear processing device according to claim 1, characterized in that, The fixed container (20) is provided with an infusion tube (21) that communicates with the pressure-reducing filtration structure. The infusion tube (21) is provided with a drive pump (24). The pressure-reducing filtration structure is a Buchner filter (5).

4. The integrated body fluid cytology smear processing device according to claim 1, characterized in that, The bottom of the pre-fixed container (1) is provided with a through cone filter (4), and the filter plate (22) is disposed inside the cone filter (4).

5. The integrated body fluid cytology smear processing device according to claim 4, characterized in that, A stop valve (23) is provided on the cone filter (4).

6. The integrated body fluid cytology smear processing device according to claim 1, characterized in that, The transparent glass container (19) has a first opening (9) above the ordinary filtration space (2) and a second opening (10) above the depressurization filtration space. The ordinary filtration structure is detachably installed on the first opening (9) and the depressurization filtration structure is detachably installed on the second opening (10).

7. The integrated body fluid cytology smear processing device according to claim 6, characterized in that, Both the first opening (9) and the second opening (10) can be detachably fitted with knob sealing covers.

8. The integrated body fluid cytology smear processing device according to claim 1, characterized in that, The transparent glass container (19) is provided with a glass partition (8), which divides the interior of the transparent glass container (19) into the ordinary filtration space (2) and the pressure-reducing filtration space (3).

9. The integrated body fluid cytology smear processing device according to claim 1, characterized in that, The transparent glass container (19) is provided with a first liquid outlet and a second liquid outlet at the bottom. The first liquid outlet is connected to the interior of the ordinary filtration space (2), and the second liquid outlet is connected to the interior of the depressurized filtration space (3).

10. The integrated body fluid cytology smear processing device according to claim 9, characterized in that, The first discharge port is connected to a first discharge pipe (15) located outside the glass container, and a first discharge valve (16) is provided on the first discharge pipe (15); the second discharge port is connected to a second discharge pipe (17) located outside the glass container, and a second discharge valve (18) is provided on the second discharge pipe (17).

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