An extractability tester

Abstract

The utility model discloses a kind of extraction degree testing instruments, it is related to the field of drug performance test technology, it includes test platform, the test platform upper end portion is equipped with several test cups, test platform upper end portion is fixedly equipped with fixed block, several test cups are located in fixed block, the side of fixed block is equipped with opening, the upper surface of fixed block is equipped with several through holes, through hole and test cup one to one correspondence, through hole is equipped with cup cover, the upper surface of fixed block is equipped with several positioning parts, several positioning parts are evenly distributed along the circumference of cup cover, positioning part is used to position cup cover, cup cover surface is equipped with stirring mouth, stirring mouth is equipped with stirring rod, two stirring vanes are fixedly equipped in the lower end portion of stirring rod, two stirring vanes are respectively located at the two sides of stirring rod, the upper end portion of test platform is fixedly equipped with support, the upper end portion of support is fixedly equipped with the driving assembly for driving stirring rod lifting and rotating. The present application has the effect of improving the accuracy of test instrument test result.

Description

Technical Field

[0001] This utility model relates to the field of drug performance testing technology, and in particular to a leaching tester. Background Technology

[0002] In today's rapidly developing pharmaceutical industry, where people's demand for health is growing, innovative drugs are constantly emerging. As a key technology for evaluating the solubility and release characteristics of drugs, the leaching tester plays an irreplaceable role in ensuring the efficacy and safety of drugs and ensuring the bioequivalence of generic drugs with original drugs.

[0003] The relevant technology mainly employs a static immersion device. The drug is placed in a glass container for immersion, and then a motor drives a stirring rod to agitate the solution. During this agitation, the stirring rod generates shear force and convection in the immersion liquid, ensuring thorough contact and mixing between the drug and the solution. This helps break down the boundary layer on the drug's surface, promoting its dissolution and diffusion. It also ensures a uniform distribution of components in the immersion liquid, reducing the occurrence of excessively high or low local concentrations.

[0004] Regarding the aforementioned technologies, in actual operation, the glass container is set with an open opening. The open stirring allows the glass container to be directly connected to the external environment. Dust, microorganisms, particulate matter and other impurities in the air can easily mix into the soaking solution. These impurities may react chemically with the medicine and interfere with the normal reaction of the medicine. Utility Model Content

[0005] To improve the accuracy of test results, this application provides a leaching tester.

[0006] This application provides a leaching tester, which adopts the following technical solution: A leaching tester includes a test platform with several test cups evenly distributed along the surface of the platform at its upper end. A fixed block is fixedly mounted on the upper end of the test platform, and the fixed block is hollow. The test cups are all located inside the fixed block. An opening is provided on one side of the fixed block, and an end cap is provided at the opening. The end cap is hinged to the fixed block, and a connector is provided between the fixed block and the end cap to reduce the probability of accidental movement of the end cap. Several through holes are provided on the upper surface of the fixed block, each corresponding to a test cup. A cup cap is provided at each through hole. Several positioning elements are provided on the upper surface of the fixed block, evenly distributed along the circumference of the cup cap to position it. A stirring port is provided on the surface of the cup cap, and a stirring rod is provided at the stirring port. Two stirring blades are fixedly mounted at the lower end of the stirring rod, and the two stirring blades are located on opposite sides of the stirring rod. A bracket is fixedly mounted on the upper end of the test platform, and a drive assembly is fixedly mounted on the upper end of the bracket to drive the stirring rod to rise, fall, and rotate.

[0007] By adopting the above technical solution, the end cap is opened, the test cup containing the liquid medicine is placed into the fixing block, and then the end cap is closed. The cup cap blocks the through hole, reducing the probability of dust and other particles entering the test cup through the through hole and causing them to move. The bracket supports the drive component. The drive component starts and drives the stirring rod to descend. The stirring rod descends from the stirring port into the test cup. The drive component drives the stirring rod to rotate, and the rotation of the stirring rod drives the stirring blade to rotate, stirring the liquid medicine in the test cup from different depths, reducing the probability of the liquid medicine reacting with the outside world and improving the accuracy of the test results of the instrument.

[0008] Optionally, the drive assembly includes a motor, a rotating rod, several gears 1, several gears 2, and a cylinder. The end of the stirring rod away from the stirring blade is provided with a connecting rod, which is detachably connected to the stirring rod and is slidably connected to the support along the width direction of the support. Gear 1 is located inside the support and is fixed at the end of the connecting rod away from the stirring rod. Gear 2 corresponds to gear 1 one by one and meshes with gear 1 and gear 2. The motor is located on one side of the support and is slidably connected to the support vertically. The rotating rod passes through all gears 2 and is fixedly connected to gears 2. The rotating rod is coaxially fixed with the output shaft of the motor. The cylinder is fixed to one side of the support and the output end of the cylinder is coaxially fixed with the motor.

[0009] By adopting the above technical solution, the cylinder starts and drives the motor to rise and fall, the motor rises and falls and drives the rotating rod to rise and fall, the rotating rod rises and falls and drives the second gear to rise and fall, the second gear rises and falls and drives the first gear to rise and fall, the first gear rises and falls and drives the connecting rod to rise and fall, and the connecting rod rises and falls and drives the stirring rod to rise and fall, so that the stirring rod enters the test cup. The motor starts and drives the rotating rod to rotate, the rotating rod rotates and drives all the second gears, the second gear rotates and drives the first gear to rotate, the first gear rotates and drives the connecting rod to rotate, and the connecting rod rotates and drives the stirring rod to rotate, so as to realize the stirring blades to stir the medicine liquid. The connecting rod and the stirring rod are detachable to facilitate the replacement of different models of stirring rods. When the test cup does not need to be stirred, the connecting rod slides, the connecting rod slides and drives the first gear to slide. At this time, the first gear and the second gear separate, which can be used to stir the test cup in a targeted manner, improving the flexibility of the tester.

[0010] Optionally, a button is provided at one end of the connecting rod near the stirring rod. The button is slidably connected to the connecting rod. A trapezoidal block is provided inside the connecting rod. The trapezoidal block is fixedly connected to the button. An elastic element is fixed between the trapezoidal block and the inner wall of the connecting rod. A locking rod is provided on both sides of the trapezoidal block. The locking rod is slidably connected to the trapezoidal block along the width direction. A locking groove corresponding to the locking rod is opened at one end of the stirring rod near the connecting rod. The locking rod is inserted into the locking groove and engages with the inner wall of the locking groove.

[0011] By adopting the above technical solution, pressing the button causes the trapezoidal block to move, the elastic element to compress, and the movement of the trapezoidal block causes the two locking rods to move in a direction that brings them closer to each other. At this time, the locking rods retract into the connecting rod, and the connecting rod is inserted into the stirring rod. When the button is released, the trapezoidal block returns to its original position under the action of the elastic element. At this time, the locking rods extend out from the connecting rod and engage with the locking groove, which improves the convenience of disassembling the stirring rod.

[0012] Optionally, the connector includes two protrusions and a plug rod. The two protrusions are fixed at both ends of the fixing block, and the end cap has a corresponding insertion hole. The protrusion is inserted into the insertion hole and engages with the inner wall of the insertion hole. The surface of the protrusion has a locking hole, and the plug rod passes through the two protrusions through the locking hole.

[0013] By adopting the above technical solution, the protrusion is inserted into the socket and engages with the inner wall of the socket, thereby positioning the end cap. Then, the insertion rod is inserted into the protrusion, further reducing the probability of the protrusion moving and improving the stability of the end cap.

[0014] Optionally, the positioning component includes a positioning block, a threaded rod, and a pressing plate. The positioning block is located at the upper end of the fixed block and is rotatably connected to the fixed block. An installation port is provided on one side of the positioning block, and the cup lid is located at the installation port. The threaded rod passes through the positioning block and is threadedly connected to the positioning block. The pressing plate is fixed at the lower end of the threaded rod and is tightly fitted to the cup lid.

[0015] By adopting the above technical solution, the positioning block is rotated to align the installation port with the cup lid, the threaded rod is rotated, the positioning block limits the threaded rod, causing the threaded rod to descend, the descending threaded rod drives the pressing plate to descend, and the pressing plate presses the cup lid.

[0016] Optionally, a feeding port is provided on the surface of the cup lid for adding liquid.

[0017] By adopting the above technical solution, the feed inlet can be conveniently used to add liquid to the test cup, and after stirring, a thermometer or other tester can be inserted to determine whether the reaction conditions have been met, thus improving the ease of use of the tester.

[0018] Optionally, the fixing block is provided with two heating plates, which are located on both sides of the fixing block and are slidably connected to the fixing block along the width direction of the fixing block.

[0019] By adopting the above technical solution, the heating plate heats the liquid medicine in the test cup. The heating plate is slidably connected to the fixed block along the width direction of the fixed block. By changing the distance between the heating plate and the test cup, the heating temperature can be controlled, thereby improving the flexibility of the tester.

[0020] Optionally, a baffle is provided at the upper end of the cup lid, which is rotatably connected to the cup lid and is used to block the stirring port.

[0021] By adopting the above technical solution, the rotating baffle blocks the stirring port, reducing the amount of foreign objects falling into the test cup when stirring is not required, thus reducing the impact on the test and improving the accuracy of the test results.

[0022] In summary, this application includes at least one of the following beneficial technical effects: 1. Open the end cap, place the test cup containing the liquid into the fixing block, and then close the end cap. The cup cap blocks the through hole, reducing the probability of dust and other particles entering the test cup through the through hole and causing a chemical reaction in the liquid, thereby improving the accuracy of the test results of the instrument. 2. When a test cup does not require stirring, slide the connecting rod. The sliding of the connecting rod will cause gear one to slide. At this time, gear one and gear two will separate, allowing for targeted stirring of the test cup and improving the flexibility of the tester. 3. Pressing the button moves the trapezoidal block, compressing the elastic element. The movement of the trapezoidal block causes the two locking rods to move closer to each other. At this time, the locking rods retract into the connecting rod, inserting the connecting rod into the stirring rod. Releasing the button resets the trapezoidal block under the action of the elastic element. At this time, the locking rods extend from the connecting rod and engage with the locking slot, improving the ease of disassembling the stirring rod. Attached Figure Description

[0023] Figure 1 This is a schematic diagram of the overall structure of a leaching tester.

[0024] Figure 2 This is a cross-sectional schematic diagram designed to highlight the support connection structure.

[0025] Figure 3 This is a schematic diagram designed to highlight the connection structure of the cup lid.

[0026] Figure 4 This is a cross-sectional schematic diagram designed to highlight the connecting rod connection structure.

[0027] Explanation of reference numerals in the attached drawings: 1. Test platform; 11. Fixing block; 111. Test cup; 112. End cap; 1121. Opening; 1122. Protrusion; 1123. Insert rod; 113. Through hole; 114. Cup lid; 1141. Positioning block; 1142. Threaded rod; 1143. Pressing plate; 1144. Stirring port; 1145. Feed inlet; 1146. Baffle; 115. Heating plate; 12. Stirring rod; 121. Stirring blade; 122. Connecting rod; 123. Button; 124. Trapezoidal block; 125. Elastic element; 126. Locking rod; 127. Locking groove; 13. Bracket; 131. Cylinder; 132. Motor; 133. Rotating rod; 134. Gear one; 135. Gear two. Detailed Implementation

[0028] The present application will be further described in detail below with reference to all the accompanying drawings.

[0029] This application discloses a leaching tester. Example

[0030] Reference Figure 1 A leaching tester includes a test platform 1. A fixing block 11 is fixedly mounted on the upper end of the test platform 1. The fixing block 11 is hollow and has an opening 1121 on one side. An end cap 112 is provided at the opening 1121 and is hinged to the fixing block 11. Two protrusions 1122 are fixedly mounted on one side of the fixing block 11. An insertion hole corresponding to the protrusions 1122 is provided at the lower end of the end cap 112. The protrusions 1122 are inserted into a through hole 113 and engaged with the inner wall of the insertion hole, thereby positioning the protrusions 1122 and the end cap 112. A locking hole is provided on the surface of the protrusions 1122 and an insertion rod 1123 is provided at the locking hole. The insertion rod 1123 is inserted into the protrusions 1122 from the locking hole, further reducing the probability of accidental movement of the protrusions 1122 and improving the stability of the end cap 112 in use.

[0031] Reference Figure 2 and Figure 3 The fixing block 11 contains several test cups 111. The test cups 111 are removed from or placed into the fixing block 11 through the opening 1121. The upper end of the fixing block 11 has a through hole 113 corresponding to the test cup 111. A cup cover 114 is provided at the through hole 113. The cup cover 114 blocks the through hole 113 to reduce the probability of dust and other particles entering the test cup 111 through the through hole 113. The upper end of the fixing block 11 has several positioning blocks 1141. The positioning blocks 1141 are evenly distributed around the cup cover 114. The positioning blocks 1141 are rotatably connected to the fixing block 11. One side of the positioning block 1141 has an opening The device has an installation port. Rotating the positioning block 1141 aligns the installation port with the cup lid 114. The upper end of the positioning block 1141 is provided with a threaded rod 1142, which is threadedly connected to the positioning block 1141. Rotating the threaded rod 1142 limits the positioning block 1141 to move the threaded rod 1142 downward. The lower end of the threaded rod 1142 is fixed with a pressing plate 1143. The downward movement of the threaded rod 1142 drives the pressing plate 1143 to move downward, pressing the cup lid 1144 with the pressing plate 1143, reducing the probability of displacement of the cup lid 114 and improving the stability of the tester.

[0032] Reference Figure 2The cup lid 114 has a stirring port 1144 on its surface, and a stirring rod 12 is provided at the stirring port 1144. A bracket 13 is fixed to the upper end of the test platform 1. A drive assembly is provided inside the bracket 13. The drive assembly includes a motor 132, a rotating rod 133, several gears 134, several gears 135, and a cylinder 131. The cylinder 131 is fixed to the upper end of the bracket 13, and the motor 132 is fixed to the output end of the cylinder 131. When the cylinder 131 is started, it drives the motor 132 to descend. The upper end of the stirring rod 12 is provided with... There is a connecting rod 122, which is detachably connected to the stirring rod 12, making it easy to replace different models of stirring rod 12. Gear 134 is located inside the bracket 13 and is fixed at the end of the connecting rod 122 away from the stirring rod 12. Gear 2 135 corresponds to gear 134 one by one and meshes with gear 134. Rotating rod 133 passes through all gears 2 135 and is fixedly connected to gear 2 135. Rotating rod 133 is coaxially fixed with the output shaft of motor 132.

[0033] Reference Figure 2 The cylinder 131 starts, driving the motor 132 to rise and fall. The rise and fall of the motor 132 drives the rotating rod 133 to rise and fall. The rise and fall of the rotating rod 133 drives the gear 135 to rise and fall. The rise and fall of the gear 135 drives the gear 134 to rise and fall. The rise and fall of the gear 134 drives the connecting rod 122 to rise and fall. The rise and fall of the connecting rod 122 drives the stirring rod 12 to rise and fall, so that the stirring rod 12 enters the test cup 111. The motor 132 starts, driving the rotating rod 133 to rotate. The rotation of the rotating rod 133 drives all the gears 135 to rotate. The rotation of the gears 135 drives the gear 134 to rotate. The rotation of rod 122 causes the connecting rod 122 to rotate, which in turn causes the stirring rod 12 to rotate. Two stirring blades 121 are fixed at the lower end of the stirring rod 12, and the two stirring blades 121 are located on both sides of the stirring rod 12. The rotation of the stirring rod 12 enables the stirring blades 121 to stir the liquid. When the test cup 111 does not need to be stirred, the connecting rod 122 is slid, and the sliding of the connecting rod 122 causes the gear 134 to slide. At this time, the gear 134 and the gear 2 135 are separated, which allows for targeted stirring of the test cup 111 and improves the flexibility of the tester.

[0034] Reference Figure 4A button 123 is provided at one end of the connecting rod 122 near the stirring rod 12. The button 123 is slidably connected to the connecting rod 122. A trapezoidal block 124 is provided inside the connecting rod 122. The trapezoidal block 124 is fixedly connected to the button 123, and an elastic element 125 is fixed between the trapezoidal block 124 and the inner wall of the connecting rod 122. A locking rod 126 is provided on both sides of the trapezoidal block 124. The locking rod 126 is slidably connected to the trapezoidal block 124 along the width direction of the trapezoidal block 124. Pressing the button 123 moves the trapezoidal block 124, and the elastic element 125... When the trapezoidal block 124 is compressed, it moves and drives the two locking rods 126 to move in a direction that brings them closer to each other. At this time, the locking rods 126 retract into the connecting rod 122, and the connecting rod 122 is inserted into the stirring rod 12. The end of the stirring rod 12 near the connecting rod 122 has a slot 127 corresponding to the locking rod 126. When the button 123 is released, the trapezoidal block 124 is reset under the action of the elastic element 125. At this time, the locking rod 126 extends out from the connecting rod 122 and engages with the slot 127, which improves the convenience of disassembling and installing the stirring rod 12.

[0035] Reference Figure 3 The upper end of the cup lid 114 is provided with a baffle 1146, which is rotatably connected to the cup lid 114. The rotating baffle 1146 blocks the stirring port 1144, reducing the amount of foreign matter falling into the test cup 111 when stirring is not required, thus minimizing the impact on the test and improving the accuracy of the test results. The surface of the cup lid 114 has a feed inlet 1145, which facilitates the addition of liquid to the test cup 111. After stirring, a thermometer or other testing instrument can be inserted to determine whether the reaction conditions have been met, improving the ease of use of the testing instrument.

[0036] Reference Figure 2 The fixed block 11 is equipped with two heating plates 115, which are located on both sides of the fixed block 11. The heating plates 115 heat the liquid medicine in the test cup 111. The heating plates 115 are slidably connected to the fixed block 11 along the width direction of the fixed block 11. By changing the distance between the heating plates 115 and the test cup 111, the heating temperature can be controlled, thereby improving the flexibility of the tester.

[0037] The implementation principle of the leaching tester in this application embodiment is as follows: Open the end cap 112, place the test cup 111 containing the drug solution into the fixing block 11, close the end cap 112, rotate the threaded rod 1142, the positioning block 1141 limits the threaded rod 1142, causing the threaded rod 1142 to descend. The descent of the threaded rod 1142 drives the pressing plate 1143 to descend, causing the pressing plate 1143 to press against the cup cover 114, blocking the through hole 113. The cylinder 131 is activated, driving the stirring rod 12 to descend. The stirring nozzle 1144 extends into the test cup 111. The motor 132 starts and drives the rotating rod 133 to rotate. The rotating rod 133 drives the gear 135 to rotate. The gear 135 drives the gear 134 to rotate. The gear 134 drives the connecting rod 122 to rotate. The connecting rod 122 drives the stirring rod 12 to rotate, so that the stirring blade 121 rotates to stir the liquid in the test cup 111, reducing the probability of the liquid coming into contact with dust and other particles in the air, and improving the accuracy of the test results.

[0038] The above are all preferred embodiments of this application, and are not intended to limit the scope of protection of this application. Therefore, all equivalent changes made in accordance with the structure, shape and principle of this application should be covered within the scope of protection of this application.

Claims

1. A leaching tester, comprising a test platform (1), characterized in that: The test platform (1) has several test cups (111) at its upper end, which are evenly distributed along the surface of the test platform (1). A fixing block (11) is fixed at the upper end of the test platform (1). The fixing block (11) is hollow, and the test cups (111) are all located inside the fixing block (11). An opening (1121) is opened on one side of the fixing block (11), and an end cap (112) is provided at the opening (1121). The end cap (112) is hinged to the fixing block (11), and a connector is provided between the fixing block (11) and the end cap (112). The connector is used to reduce the probability of the end cap (112) moving accidentally. Several through holes (113) are opened on the upper surface of the fixing block (11). Corresponding to the test cup (111), a cup lid (114) is provided at the through hole (113). Several positioning parts are provided on the upper surface of the fixing block (11). The positioning parts are evenly distributed around the cup lid (114). The positioning parts are used to position the cup lid (114). A stirring port (1144) is opened on the surface of the cup lid (114). A stirring rod (12) is provided at the stirring port (1144). Two stirring blades (121) are fixed at the lower end of the stirring rod (12). The two stirring blades (121) are located on both sides of the stirring rod (12). A bracket (13) is fixed at the upper end of the test platform (1). A drive assembly is fixed at the upper end of the bracket (13). The drive assembly is used to drive the stirring rod (12) to rise, fall and rotate.

2. The leaching tester according to claim 1, characterized in that: The drive assembly includes a motor (132), a rotating rod (133), several gears (134), several gears (135), and a cylinder (131). A connecting rod (122) is provided at one end of the stirring rod (12) away from the stirring blade (121). The connecting rod (122) is detachably connected to the stirring rod (12), and the connecting rod (122) is slidably connected to the support (13) along the width direction of the support (13). Gears (134) are located inside the support (13), and gears (134) are fixed to the connecting rod (122) at the end away from the stirring rod (12). At one end, gear two (135) corresponds one-to-one with gear one (134), and gear one (134) meshes with gear two (135). Motor (132) is located on one side of bracket (13), and motor (132) is slidably connected to bracket (13) in the vertical direction. Rotating rod (133) passes through all gear two (135) and is fixedly connected to gear two (135). Rotating rod (133) is coaxially fixed with the output shaft of motor (132). Cylinder (131) is fixed on one side of bracket (13), and the output end of cylinder (131) is coaxially fixed with motor (132).

3. The leaching tester according to claim 2, characterized in that: The connecting rod (122) has a button (123) at one end near the stirring rod (12). The button (123) is slidably connected to the connecting rod (122). A trapezoidal block (124) is provided inside the connecting rod (122). The trapezoidal block (124) is fixedly connected to the button (123). An elastic element (125) is fixed between the trapezoidal block (124) and the inner wall of the connecting rod (122). A locking rod (126) is provided on both sides of the trapezoidal block (124). The locking rod (126) is slidably connected to the trapezoidal block (124) along the width direction of the trapezoidal block (124). A slot (127) corresponding to the locking rod (126) is opened at one end of the stirring rod (122) near the connecting rod (122). The locking rod (126) is inserted into the slot (127) and engaged with the inner wall of the slot (127).

4. The leaching tester according to claim 3, characterized in that: The connector includes two protrusions (1122) and a plug (1123). The two protrusions (1122) are fixed at both ends of the fixing block (11). The end cap (112) has a corresponding insertion hole for the protrusions (1122). The protrusions (1122) are inserted into the insertion holes and engaged with the inner wall of the insertion holes. The surface of the protrusions (1122) has a locking hole. The plug (1123) passes through the two protrusions (1122) through the locking hole.

5. The leaching tester according to claim 1, characterized in that: The positioning component includes a positioning block (1141), a threaded rod (1142), and a pressing plate (1143). The positioning block (1141) is located at the upper end of the fixing block (11), and the positioning block (1141) is rotatably connected to the fixing block (11). An installation port is provided on one side of the positioning block (1141), and the cup lid (114) is located at the installation port. The threaded rod (1142) passes through the positioning block (1141) and is threadedly connected to the positioning block (1141). The pressing plate (1143) is fixed at the lower end of the threaded rod (1142), and the pressing plate (1143) is tightly fitted to the cup lid (114).

6. The leaching tester according to claim 1, characterized in that: The cup lid (114) has a feed inlet (1145) on its surface, which is used to add liquid.

7. The leaching tester according to claim 1, characterized in that: The fixing block (11) is provided with two heating plates (115), which are located on both sides of the fixing block (11) and are slidably connected to the fixing block (11) along the width direction of the fixing block (11).

8. The leaching tester according to claim 1, characterized in that: The upper end of the cup lid (114) is provided with a baffle (1146), which is rotatably connected to the cup lid (114) and is used to block the stirring port (1144).

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