Nitric oxide generation system based on dielectric barrier discharge

CN224610971UActive Publication Date: 2026-08-07SHENGKE QIANTU TECHNOLOGY (CHENYANG) CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
SHENGKE QIANTU TECHNOLOGY (CHENYANG) CO LTD
Filing Date
2025-05-19
Publication Date
2026-08-07

AI Technical Summary

Technical Problem

[0004]目前的NO吸入疗法都必须通过气体高压钢瓶存储、运输,使用极不便利;高浓度的NO长期存储容易产生副反应、毒副作用大;低发生效率和高提纯难度,限制了NO气体的临床使用;且目前正在使用的大部分为工业级NO气体,也难以应用于非ICU的临床和产业化;钢瓶NO气体浓度很高,安全性也有隐患;NO存储和运输耗力耗成本,装置复杂

Benefits of technology

[0014] The present invention provides a nitric oxide generation system based on dielectric barrier discharge. This system can generate nitric oxide in real time. The system has the advantages of small size, easy transportation, convenient use, low cost and high generation efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a nitric oxide generating system based on dielectric barrier discharge, and the system comprises: air pump, plasma chamber, gas flow control meter, control circuit, the plasma chamber is sealed structure, be equipped with air inlet, gas outlet on the plasma chamber body, the plasma chamber body outside sleeve joint has outer electrode, is equipped with inner electrode in it, and the inner electrode is cylindrical structure, and the through setting with the center in plasma cavity, through control circuit with the inner electrode, outer electrode are connected to the alternating -current is applied between two poles, control circuit includes power supply, voltage frequency regulation controller, transformer, ammeter, the air pump is connected with the air inlet of plasma chamber through the air inlet pipeline, and the gas flow control meter is installed on the air inlet pipeline, and the gas outlet is connected with product collecting device. The system has the advantages of small size, convenient transportation, convenient to use, low cost, high generation efficiency etc.
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Description

Technical Field

[0001] This utility model relates to the field of nitric oxide generation technology, and in particular to a nitric oxide generation system based on dielectric barrier discharge. Background Technology

[0002] Nitric oxide (NO) is a colorless, odorless, lipid-soluble gas widely distributed throughout human tissues. It diffuses rapidly across biological membranes without any intermediary mechanisms, transmitting information generated by one cell to surrounding cells and participating in the regulation of cellular physiological activities. It is a crucial intercellular signaling molecule, playing a key regulatory role in many physiological and pathological processes. When inhaled exogenously, NO is a selective pulmonary vasodilator, an effective treatment for pulmonary hypertension and neonatal hypoxic respiratory failure, with over twenty years of clinical application. Its safety and efficacy have been validated, and its application has gradually expanded to include acute respiratory distress syndrome, severe pneumonia, high-altitude pulmonary edema, acute pulmonary embolism, heart failure, and severe postoperative hypoxemia, achieving good results.

[0003] NO was only discovered more than a century after its initial use to be an endogenous small molecule with important physiological functions, and a highly effective cardiovascular drug. Its main functions include increasing vasodilation, preventing platelet adhesion, promoting wound healing and angiogenesis, and acting as an effective antibacterial agent through release from macrophages and nasal epithelial cells.

[0004] Current NO inhalation therapy requires storage and transportation in high-pressure gas cylinders, which is extremely inconvenient. Long-term storage of high-concentration NO can easily lead to side effects and significant toxicity. Low generation efficiency and high purification difficulty limit the clinical use of NO gas. Moreover, most of the NO gas currently in use is industrial-grade, which is difficult to apply to non-ICU clinical settings and industrialization. The high concentration of NO gas in cylinders also poses safety risks. NO storage and transportation are labor-intensive, costly, and involve complex equipment. Utility Model Content

[0005] In view of this, the present invention provides a nitric oxide generation system based on dielectric barrier discharge, so as to achieve nitric oxide generation in a convenient and efficient manner.

[0006] This invention provides a nitric oxide generation system based on dielectric barrier discharge, comprising: a gas pump, a plasma chamber, a gas flow controller, and a control circuit;

[0007] The plasma chamber is a sealed structure, including an inlet insulating connector, an outlet insulating connector, an inner electrode, an outer electrode, a dielectric material layer, and a sealing flange. The outer electrode is a hollow cylindrical structure, with its two ends connected to the inlet insulating connector and the outlet insulating connector respectively to form an integral hollow cylindrical structure. The inner electrode is a cylindrical structure, located at the center of the integral hollow cylindrical structure, and its two ends are fixed by sealing flanges. The dielectric material layer is sleeved on the outer surface of the inner electrode.

[0008] The control circuit is connected to the inner and outer electrodes to apply alternating current between the two electrodes to form plasma between the dielectric material layer and the inner surface of the outer electrode.

[0009] The air pump is connected to the air inlet of the inlet insulated connector via an air inlet pipe, and the gas flow controller is installed on the air inlet pipe; the air outlet of the outlet insulated connector is connected to the product collection device.

[0010] Preferably, the control circuit includes a power supply, a voltage and frequency regulator, a transformer, and an ammeter;

[0011] Preferably, it also includes a heat dissipation device, which is placed around the plasma chamber to dissipate heat from the plasma chamber.

[0012] Preferably, the plasma chamber body is a tubular structure.

[0013] Preferably, the dielectric material layer of the plasma chamber is one of alumina, glass, or quartz.

[0014] The present invention provides a nitric oxide generation system based on dielectric barrier discharge. This system can generate nitric oxide in real time. The system has the advantages of small size, easy transportation, convenient use, low cost and high generation efficiency.

[0015] It should be understood that the above general description and the following detailed description are exemplary and explanatory only, and do not limit the disclosure of this utility model. Attached Figure Description

[0016] Figure 1 A schematic diagram of the composition and structure of the nitric oxide generation system based on dielectric barrier discharge provided by this utility model. Detailed Implementation

[0017] The present invention will be further explained below with reference to specific implementation schemes, but this is not intended to limit the scope of protection of the present invention.

[0018] Current NO inhalation therapy requires storage and transportation in high-pressure gas cylinders, which is extremely inconvenient. Long-term storage of high-concentration NO can easily cause side effects and toxic side effects. Low generation efficiency and high purification difficulty limit the clinical use of NO gas. To address the above problems, this implementation plan provides a nitric oxide generation system based on dielectric barrier discharge, including: a gas pump 1, a plasma chamber 2, a gas flow controller 3, a control circuit, and a product collection device 5.

[0019] Specifically, the air pump 1 mentioned above is used to absorb air;

[0020] Gas flow controller 3 is used to adjust gas flow parameters, with a gas flow range of 0-6L / min;

[0021] Plasma chamber 2 uses dielectric barrier discharge. When an alternating current is applied between the two electrodes, plasma is formed, which ionizes the nitrogen and oxygen in the input air into free nitrogen and oxygen atoms, which combine to form nitric oxide. Nitric oxide reacts with air to generate nitrogen dioxide.

[0022] The heat dissipation device 4 can be a fan, used to dissipate heat from the plasma chamber;

[0023] The control circuit is connected to the inner and outer electrodes to apply alternating current between the two electrodes. When alternating current is applied between the two electrodes, plasma is formed, which ionizes the air and causes free nitrogen to combine with oxygen to form nitric oxide.

[0024] The control circuit includes a power supply, a voltage and frequency regulator controller, a transformer, and an ammeter;

[0025] The voltage and frequency regulator can adjust the frequency parameter, which ranges from 13 to 17 kHz, and can also adjust the voltage parameter, which ranges from 0 to 250 volts, by connecting an external transformer to regulate the amount of nitric oxide and nitrogen dioxide in the final product gas. In the control circuit structure, the low-voltage terminals of each component are connected to the neutral wire, and the high-voltage terminals of each component are connected in series, forming a high-voltage loop from the controller to the transformer to the ammeter to the plasma chamber.

[0026] The plasma chamber 2 is a sealed structure, including an inlet insulating connector, an outlet insulating connector, an inner electrode 22, an outer electrode, a dielectric material layer 6, and a sealing flange; wherein the outer electrode is a hollow cylindrical structure, and the two ends of the outer electrode 21 are respectively connected to the inlet insulating connector and the outlet insulating connector to form an integral hollow cylindrical structure; the inner electrode 22 is a cylindrical structure, located at the center of the integral hollow cylindrical structure, and its two ends are fixed by sealing flanges; the dielectric material layer 6 is sleeved on the outer surface of the inner electrode;

[0027] The gas pump 1 is connected to the air inlet of the plasma chamber 2 through the air inlet pipe, and the gas flow controller 3 is installed on the air inlet pipe; the air outlet is connected to the product collection device 5.

[0028] A heat dissipation device is placed around the plasma chamber to dissipate heat from the plasma chamber. Existing equipment such as fans can be used for this purpose.

[0029] The reaction process using the above system is as follows: the gas pump absorbs air, the gas flow controller adjusts the air intake flow, and then the gas enters the plasma chamber to react fully, ionizing the nitrogen and oxygen in the air to generate nitric oxide and nitrogen dioxide. The amount and ratio of nitric oxide and nitrogen dioxide generated in the plasma chamber can be changed by adjusting the frequency and voltage parameters of the controller.

[0030] Specifically, this implementation scheme provides a method for generating nitric oxide based on dielectric barrier discharge, including:

[0031] The air pump 1 is turned on to draw in air, which enters the plasma chamber through the air inlet. The gas flow rate entering the plasma chamber is regulated by the gas flow controller 3.

[0032] When the power is turned on, a dielectric barrier discharge is used. When an alternating current is applied between the inner and outer poles of the plasma chamber 2, plasma is formed, which ionizes the nitrogen and oxygen in the input air into free nitrogen and oxygen atoms, which combine to form nitric oxide. Nitric oxide reacts with air to generate nitrogen dioxide.

[0033] By adjusting the voltage frequency controller and transformer, that is, by adjusting the voltage frequency and voltage parameters, the amount and ratio of nitric oxide and nitrogen dioxide generated in the final product gas can be changed.

[0034] Preferably, the frequency is 13-17KHz; the gas flow rate parameter range is 0-6L / min; and the voltage parameter range is 0-250V.

[0035] The dielectric material of the plasma chamber is one of alumina, glass, or quartz. This system uses dielectric barrier discharge (DBD) to generate cold plasma at atmospheric pressure. A dielectric barrier exists within the device to prevent excessive charge and thermal arcing from accumulating in the plasma.

[0036] The plasma chamber body is a tubular structure, with the inlet and outlet located at its left and right ends, respectively. The tubular flow structure reduces capacitance by increasing the barrier thickness while retaining charge, thereby increasing the voltage on the dielectric and generating a large number of micro-discharges, thus improving the conversion efficiency of nitrogen oxides.

[0037] The effects of frequency, intake flow rate, and voltage on the generation of nitric oxide and nitrogen dioxide were investigated. The results showed that under the condition of the highest frequency (17 kHz), changing the intake flow rate and voltage affected the generation and ratio of nitric oxide and nitrogen dioxide, as shown in Table 1.

[0038] Table 1

[0039]

[0040] Other embodiments of the present invention will readily occur to those skilled in the art upon consideration of the specification and practice of the invention disclosed herein. This application is intended to cover any variations, uses, or adaptations of the invention that follow the general principles of the invention and include common knowledge or customary techniques in the art not disclosed herein. The specification and examples are to be considered exemplary only, and the true scope and spirit of the invention are indicated by the following claims.

[0041] It should be understood that this utility model is not limited to the content already described above, and various modifications and changes can be made without departing from its scope. The scope of this utility model is limited only by the appended claims.

Claims

1. A nitric oxide generation system based on dielectric barrier discharge, characterized in that, include: Gas pump (1), plasma chamber (2), gas flow controller (3), control circuit; The plasma chamber (2) is a sealed structure, including an inlet insulating connector, an outlet insulating connector, an inner electrode (22), an outer electrode (21), a dielectric material layer (6), and a sealing flange; wherein the outer electrode (21) is a hollow cylindrical structure, and the two ends of the outer electrode (21) are respectively connected to the inlet insulating connector and the outlet insulating connector to form an integrated hollow cylindrical structure; the inner electrode (22) is a cylindrical structure, located at the center of the integrated hollow cylindrical structure, and its two ends are fixed by sealing flanges; the dielectric material layer (6) is sleeved on the outer surface of the inner electrode; The control circuit is connected to the inner and outer electrodes to apply alternating current between the two electrodes to form plasma between the dielectric material layer and the inner surface of the outer electrode. The air pump (1) is connected to the air inlet of the air inlet insulating connector through the air inlet pipe, and the gas flow controller (3) is installed on the air inlet pipe; the air outlet of the air outlet insulating connector is connected to the product collection device (5).

2. The nitric oxide generation system based on dielectric barrier discharge according to claim 1, characterized in that, The control circuit includes a power supply, a voltage and frequency regulator controller, a transformer, and an ammeter.

3. The nitric oxide generation system based on dielectric barrier discharge according to claim 1, characterized in that, It also includes a heat dissipation device (4), which is placed around the plasma chamber to dissipate heat from the plasma chamber.

4. The nitric oxide generation system based on dielectric barrier discharge according to claim 1, characterized in that, The plasma chamber (2) has a tubular structure.