A rotating disc type ion exchange device for purifying arginine

Abstract

This invention provides a rotary ion-exchange arginine purification device, comprising a cation exchange system, an anion exchange system, and an intermediate buffer tank connecting the two. The cation exchange system includes multiple cation exchange columns connected by a first pipeline and a first rotary multi-way valve group. The anion exchange system includes multiple anion exchange columns connected by a second pipeline and a second rotary multi-way valve group. This invention utilizes the rotary multi-way valve group to precisely control the ion exchange columns in each system to form various parallel, series, and composite flow path modes, realizing fully automated and continuous operation of adsorption, desorption, decolorization, and regeneration processes in arginine purification. This significantly improves production efficiency and product purity, and greatly reduces reagent consumption, wastewater discharge, and labor costs.

Description

Technical Field

[0001] This utility model relates to a rotary ion exchange arginine purification device. Background Technology

[0002] Arginine has wide applications in pharmaceuticals, food, and chemicals, with continuously growing market demand and increasingly stringent requirements for its purity. Traditional arginine purification methods often suffer from low efficiency, high cost, and unstable product quality, making it difficult to meet the demands of large-scale industrial production and high-end markets. Continuous ion exchange technology, as a highly efficient separation and purification method, offers advantages such as large throughput, continuous operation, and excellent separation results, and has been successfully applied in the purification of various substances. This project aims to develop equipment for purifying arginine using continuous ion exchange. Through processes such as cation exchange adsorption of the target product and anion exchange decolorization, combined with precise control of feed and discharge parameters and optimized equipment performance design, the project achieves efficient and stable purification of arginine. The implementation of this project is expected to overcome the bottlenecks of traditional purification technologies, improve arginine production efficiency and product quality, reduce production costs, enhance market competitiveness, and meet market demand for high-quality arginine. Utility Model Content

[0003] This invention provides a rotary ion exchange arginine purification device that can effectively solve the above-mentioned problems.

[0004] This utility model is implemented as follows:

[0005] A rotary ion exchange arginine purification device includes a cation exchange system, an anion exchange system, and an intermediate buffer tank connecting the two.

[0006] The cation exchange system includes multiple cation exchange columns connected by a first pipeline and a first rotary multi-way valve group; the anion exchange system includes multiple anion exchange columns connected by a second pipeline and a second rotary multi-way valve group.

[0007] The inlet of the intermediate buffer tank is connected to the water washing material outlet of the cation exchange system and the water washing material outlet of the anion exchange system via pipelines; the outlet of the intermediate buffer tank is connected to the secondary inlet of the cation exchange system and the secondary inlet of the anion exchange system via an intermediate feed pump.

[0008] The cation exchange system is also equipped with an inlet for the desorbent connected to an ammonia source, an inlet for the pressurized air connected to a compressed air source, and an outlet for the desorbed liquid connected to a pre-desorbing tank; the anion exchange system is also equipped with an acid regeneration inlet connected to an acid source, an alkali regeneration inlet connected to an alkali source, and a regenerated waste liquid outlet connected to a high-concentration waste liquid collection device and a low-concentration waste liquid collection device, respectively.

[0009] The beneficial effects of this utility model are:

[0010] (1) This utility model integrates and couples the cation exchange system and the anion exchange system through an intermediate buffer tank, and uses a rotary multi-way valve group to precisely control the ion exchange columns in each system to form a variety of parallel, series and composite flow path modes, thereby realizing the fully automatic continuous operation of adsorption, desorption, decolorization and regeneration processes in the purification of arginine, which significantly improves production efficiency and product purity, and greatly reduces reagent consumption, wastewater discharge and labor costs. Attached Figure Description

[0011] To more clearly illustrate the technical solutions of the embodiments of this utility model, the drawings used in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of this utility model and should not be regarded as a limitation of the scope. For those skilled in the art, other related drawings can be obtained from these drawings without creative effort.

[0012] Figure 1 This is a process flow diagram of the male and female column system of this utility model.

[0013] Figure 2 This is a flowchart of the present invention.

[0014] Figure 3 This is a flow path diagram of this utility model. Detailed Implementation

[0015] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model. Therefore, the following detailed description of the embodiments of this utility model provided in the accompanying drawings is not intended to limit the scope of the claimed utility model, but merely to represent selected embodiments of this utility model.

[0016] In the description of this utility model, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly specified.

[0017] Reference Figure 1-3 As shown, a rotary ion exchange arginine purification device includes a cation exchange system, an anion exchange system, and an intermediate buffer tank connecting the two.

[0018] The cation exchange system includes multiple cation exchange columns connected by a first pipeline and a first rotary multi-way valve assembly; the anion exchange system includes multiple anion exchange columns connected by a second pipeline and a second rotary multi-way valve assembly.

[0019] The first pipeline is configured to create a "four-in-one," "four-in-two-in-one," or "three-in-one" flow path between the cation exchange columns; the second pipeline is configured to create a "three-in-one-two-in-one" or "two-in-one" flow path between the anion exchange columns. Specifically, the flow path patterns described in this embodiment are achieved by switching between the first and second rotary multi-way valve groups, as follows:

[0020] Reference Figure 3 As shown, the "four-parallel" mode refers to the feed liquid being divided into four equal streams by a valve group, each simultaneously entering one of four parallel-connected ion exchange columns for processing. The processed liquids are then combined for output. The "four-parallel, two-series" mode refers to the feed liquid being divided into two equal streams by a valve group. Each stream enters a sub-group consisting of two ion exchange columns connected in series (two sub-groups in total). The liquid passes through the two columns in series within each sub-group, and the outputs from the two sub-groups are then combined. This mode is a composite mode of parallel-then-series connection. The "three-series" mode refers to the feed liquid being passed sequentially through three ion exchange columns by a valve group. The effluent from the first column serves as the influent for the second column, and vice versa. The "three-parallel, two-series" mode refers to the feed liquid being divided into three equal streams by a valve group, each simultaneously entering one of three parallel-connected ion exchange columns for processing. The processed liquids are then combined for output. The "two-series" mode refers to the feed liquid being passed sequentially through two ion exchange columns by a valve group.

[0021] The inlet of the intermediate buffer tank is connected to the water washing material outlet of the cation exchange system and the water washing material outlet of the anion exchange system via pipelines; the outlet of the intermediate buffer tank is connected to the secondary feed inlet of the cation exchange system and the secondary feed inlet of the anion exchange system via an intermediate feed pump; the cation exchange system is also equipped with an inlet for the desorption agent connected to the ammonia water source, an inlet for the pressurized air connected to the compressed air source, and an outlet for the desorption liquid connected to the pre-desorption tank; the anion exchange system is also equipped with an acid regeneration inlet connected to the acid source, an alkali regeneration inlet connected to the alkali source, and regeneration waste liquid outlets connected to the high-concentration waste liquid collection device and the low-concentration waste liquid collection device, respectively.

[0022] The cation exchange system also includes a pre-extraction pump. The inlet of the pre-extraction tank is connected to the outlet of the elution liquid of the cation exchange column, and the outlet of the pre-extraction tank is connected to the pre-extraction inlet of the cation exchange column through the pre-extraction pump, forming a pre-extraction circulation loop. This allows the elution liquid (containing free ammonia) to be reused in the pre-extraction step, saving ammonia water consumption and stabilizing the ammonia concentration in the product liquid.

[0023] The anion exchange system is also equipped with a alkali tank and an alkali pre-regeneration pump. The inlet of the alkali tank is connected to the alkali regeneration outlet of the anion exchange column, and the outlet of the alkali tank is connected to the pre-regeneration inlet of the anion exchange column through the alkali pre-regeneration pump. The feed direction of the pre-regeneration inlet is reverse feeding, so that the low-concentration alkali solution after regeneration can be collected and reused for pre-regeneration, which greatly reduces alkali consumption and wastewater discharge.

[0024] The anion exchange system is equipped with an automatic switching valve at the outlet of the regeneration waste liquid. The outlet of the automatic switching valve leads to a high-concentration waste liquid collection device and a low-concentration waste liquid collection device, respectively.

[0025] The cation exchange system's pressurizing air inlet is connected to a compressed air source via a pipeline. This inlet leads to the top of the cation exchange column, where it is used to press out water accumulated inside the column. The pressed-out water is then returned to the front end of the system for reuse via a return pipe. Specifically, the water pressed out during the pressurizing operation and the water ejected during the ejection operation are designed to be reused in the preceding process, reflecting an energy-saving and environmentally friendly design concept.

[0026] The anion exchange system is equipped with a top feed inlet, which is connected to the final product liquid outlet via a product liquid reverse pump. This pump is used to reverse the flow of the product liquid into the anion exchange column for top feed operation, and the ejected water is reused in the alkali washing process.

[0027] The first and second rotary multi-way valve groups are automatic control rotary valves or multi-way solenoid valve groups. All pumps and valves of the equipment are programmed and controlled by the central controller to achieve fully automatic continuous operation.

[0028] Both the cation exchange column and the anion exchange column are equipped with water distributors at the top and bottom. The water distributors have a double-layer disc structure with sieve holes evenly distributed on the disc surface. This ensures that the liquid is evenly distributed when passing through the resin column, preventing channeling or dead zones, greatly improving the resin utilization efficiency and exchange effect, and is the basic hardware for ensuring high separation efficiency.

[0029] The intermediate buffer tank is equipped with an online pH meter and a level sensor. The central controller is connected to the online pH meter, the level sensor, and the concentrated acid addition pump to form a closed-loop control system, which is used to automatically maintain the pH value and level stability of the liquid in the intermediate buffer tank.

[0030] The automatic switching valve is a conductivity-controlled valve, which is connected to a conductivity meter installed on the outlet pipeline of the regenerated waste liquid. The central controller controls the opening, closing and switching of the automatic switching valve according to the value fed back by the conductivity meter.

[0031] Working Principle: The arginine feed solution is first pumped into the cation exchange system. This system dynamically switches between parallel and series flow modes (such as four parallel or four parallel with two series) through a first rotary multi-way valve group precisely programmed and controlled by a central controller. This allows the effective substances in the feed solution to be efficiently adsorbed by the cation exchange resin, while impurities flow out with the liquid. After adsorption, the resin column undergoes water washing and compressed air pressure drainage before switching to the desorption zone. Ammonia water is used in a series mode for desorption, eluting and collecting the adsorbed arginine. The ammonia-containing product solution generated during desorption can be partially recycled to the pre-desorption tank for the pre-desorption step to save reagents. The effluent from the cation exchange system and the washing liquid from each stage all flow into the intermediate buffer tank. This tank has built-in pH and level sensors and is controlled by a closed-loop system. After automatic replenishment of concentrated acid and precise pH adjustment, the solution is pumped to the anion exchange system. The anion system also controls the flow path (e.g., three parallel and two series) through a second rotary multi-way valve group, specifically adsorbing pigments for decolorization, ultimately yielding a high-transmittance arginine product solution. The decolorized anion resin undergoes acid regeneration, water washing (wastewater is automatically diverted according to conductivity value), alkali regeneration (alkali solution is reused and recovered), and water washing (alkali solution is recovered) to restore its activity. The residual water in the column is recovered by backflow of the product solution. Throughout the process, all flow path switching, reagent addition, wastewater diversion, and resource recycling are fully automatically controlled by the central controller, thus realizing continuous, efficient, stable, and low-consumption automated production of arginine from adsorption and desorption to decolorization and regeneration.

[0032] It should be noted that the electronic products used in this plan are all existing technologies, so their models and functions will not be described in detail.

[0033] The above description is merely a preferred embodiment of this utility model and is not intended to limit the utility model. Various modifications and variations can be made to this utility model by those skilled in the art. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A rotating disc ion exchange arginine purification device, characterized in that, It includes a cation exchange system, an anion exchange system, and an intermediate buffer tank connecting the two; The cation exchange system includes multiple cation exchange columns connected by a first pipeline and a first rotary multi-way valve group; the anion exchange system includes multiple anion exchange columns connected by a second pipeline and a second rotary multi-way valve group. The inlet of the intermediate buffer tank is connected to the water washing material outlet of the cation exchange system and the water washing material outlet of the anion exchange system via pipelines; the outlet of the intermediate buffer tank is connected to the secondary inlet of the cation exchange system and the secondary inlet of the anion exchange system via an intermediate feed pump. The cation exchange system is also equipped with an inlet for the desorbent connected to an ammonia source, an inlet for the pressurized air connected to a compressed air source, and an outlet for the desorbed liquid connected to a pre-desorbing tank; the anion exchange system is also equipped with an acid regeneration inlet connected to an acid source, an alkali regeneration inlet connected to an alkali source, and a regenerated waste liquid outlet connected to a high-concentration waste liquid collection device and a low-concentration waste liquid collection device, respectively.

2. The rotary ion exchange arginine purification device according to claim 1, characterized in that, The cation exchange system also includes a pre-extraction pump. The inlet of the pre-extraction tank is connected to the outlet of the elution liquid of the cation exchange column, and the outlet of the pre-extraction tank is connected to the pre-extraction inlet of the cation exchange column through the pre-extraction pump, forming a pre-extraction circulation loop.

3. The rotary ion exchange arginine purification device according to claim 1, characterized in that, The anion exchange system is also equipped with a alkali tank and an alkali pre-regeneration pump; the inlet of the alkali tank is connected to the alkali regeneration outlet of the anion exchange column, and the outlet of the alkali tank is connected to the pre-regeneration inlet of the anion exchange column through the alkali pre-regeneration pump, and the feed direction of the pre-regeneration inlet is reverse feeding.

4. The rotary ion exchange arginine purification device according to claim 1, characterized in that, The anion exchange system is equipped with an automatic switching valve at the outlet of the regenerated waste liquid, and the outlet of the automatic switching valve leads to a high-concentration waste liquid collection device and a low-concentration waste liquid collection device, respectively.

5. The rotary ion exchange arginine purification device according to claim 1, characterized in that, The pressurizing air inlet of the cation exchange system is connected to a compressed air source via a pipeline. The pressurizing air inlet leads to the top of the cation exchange column and is used to press out the water accumulated inside the column. The pressed-out water is returned to the front end of the system for reuse through a return pipe.

6. The rotary ion exchange arginine purification device according to claim 1, characterized in that, The anion exchange system is equipped with a top feed inlet, which is connected to the final product liquid outlet via a product liquid reverse pump. This pump is used to reverse the flow of the product liquid into the anion exchange column for a top feed operation, and the water ejected is reused in the alkali washing process.

7. The rotary ion exchange arginine purification device according to claim 1, characterized in that, The first and second rotary multi-way valve groups are automatic control rotary valves or multi-way solenoid valve groups. All pumps and valves of the device are programmed and controlled by a central controller to achieve fully automatic continuous operation.

8. The rotary ion exchange arginine purification device according to claim 1, characterized in that, Both the top and bottom of the cation exchange column and the anion exchange column are equipped with water distributors. The water distributors have a double-layer disc structure with sieve holes evenly distributed on the disc surface.

9. The rotary ion exchange arginine purification device according to claim 1, characterized in that, It also includes a central controller. The intermediate buffer tank is equipped with an online pH meter and a liquid level sensor. The central controller is connected to the online pH meter, the liquid level sensor and the concentrated acid addition pump to form a closed-loop control system, which is used to automatically maintain the pH value and liquid level stability of the liquid in the intermediate buffer tank.

10. A rotary ion exchange arginine purification device according to claim 4, characterized in that, It also includes a central controller, and the automatic switching valve is a conductivity control valve, which is connected to a conductivity meter installed on the outlet pipeline of the regenerated waste liquid. The central controller controls the opening, closing and switching of the automatic switching valve according to the value fed back by the conductivity meter.

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