Quality control card, blood cell analyzer

Abstract

This application discloses a quality control card and a hematology analyzer. The quality control card includes a first plate and a pattern layer. The first plate has at least one detection area, and the pattern layer is disposed in the detection area. The pattern layer includes a cell pattern composed of a plurality of quality control cells arranged in a proportional relationship with the size of real blood cells. Therefore, this application can perform calibration tests on the hematology analyzer by setting a cell pattern corresponding to the size of real blood cells on the quality control card, eliminating the need to prepare real quality control samples. This reduces the preparation time and consumable consumption of real quality control samples, reduces or avoids the expiration date limitations caused by using real quality control samples, and improves the quality control efficiency of the hematology analyzer.

Description

Technical Field

[0001] This application relates to the field of sample testing technology, and in particular to quality control cards and blood cell analyzers. Background Technology

[0002] When a blood cell analyzer performs sample testing using cell imaging, it places the sample to be tested on a test card and acquires the sample image data of the test card through the detection component. The subsequent cell identification and counting are then performed based on the sample image data.

[0003] Current hematology analyzers typically require the creation of quality control samples from real blood samples (such as human or animal blood) during calibration testing. These quality control samples are then added to a test card, allowing the analyzer to calibrate the card. However, limitations in the manufacturing process and shelf life of real blood samples result in differences in cell morphology between the prepared quality control samples and fresh samples after liquid-based staining. Furthermore, the preparation of quality control samples is time-consuming and resource-intensive. Consequently, the quality control effectiveness and efficiency of current hematology analyzers are unsatisfactory. Utility Model Content

[0004] To address the aforementioned problems in the prior art, this application provides a quality control card and a blood cell analyzer.

[0005] To address the technical problems existing in the prior art, this application provides a first technical solution: a quality control card for a blood cell analyzer, the quality control card comprising a first plate and a pattern layer, the first plate having at least one detection area, the pattern layer being disposed in the detection area, the pattern layer comprising a cell pattern formed by a plurality of quality control cells arranged therein; the size of the quality control cells being proportional to the size of real blood cells.

[0006] Optionally, the first plate includes at least two detection zones, and the types of quality control cells corresponding to the at least two detection zones are different.

[0007] Optionally, the first plate includes a first detection area, a second detection area, and a third detection area; the quality control card includes a first pattern layer, a second pattern layer, and a third pattern layer; the first pattern layer is disposed in the first detection area; the second pattern layer is disposed in the second detection area; and the third pattern layer is disposed in the third detection area. The first pattern layer is printed with an image of red blood cells arranged in a plurality of red blood cells; the second pattern layer is printed with an image of white blood cells arranged in a plurality of white blood cells; and the third pattern layer is printed with an image of platelets arranged in a plurality of platelets.

[0008] Optionally, the quality control card further includes a protective layer, with the cell pattern located between the first plate and the protective layer.

[0009] Optionally, the protective layer is a transparent layer, and an anti-reflective coating is provided on the protective layer.

[0010] Optionally, the first plate includes a first detection area, a second detection area, and a third detection area; the quality control card includes a first pattern layer, a second pattern layer, and a third pattern layer; the first pattern layer is disposed in the first detection area; the second pattern layer is disposed in the second detection area; and the third pattern layer is disposed in the third detection area. The quality control cells on the first pattern layer, the second pattern layer, and the third pattern layer have the same cell type, and the number of quality control cells on the first pattern layer, the second pattern layer, and the third pattern layer increases progressively.

[0011] Optionally, the first plate includes at least two detection zones; the real blood cells include abnormal blood cells, the size of the control cells in the cell pattern on at least one detection zone is proportional to the size of the abnormal blood cells, and / or, the number of control cells in the cell pattern on at least one detection zone is proportional to the number of abnormal blood cells, and / or, the shape of the control cells in the cell pattern on at least one detection zone is the same as the shape of the abnormal blood cells.

[0012] Optionally, the size of the quality control cells is consistent with the size of real blood cells; the first plate is a transparent plate, and the pattern layer has a transmittance of a preset threshold.

[0013] To address the technical problems existing in the prior art, this application provides a second technical solution: a blood cell analyzer, which is used to calibrate and test the quality control card as described above to obtain quality control results.

[0014] Optionally, the aforementioned blood cell analyzer includes a carrier component and a detection component; the carrier component is used to receive a test card, the test card containing a sample to be tested, and also to receive the quality control card; the detection component is connected to the carrier component, and is used to acquire a quality control image of the cell pattern on the quality control card, and obtain the quality control result of the blood cell analyzer based on the quality control image; the detection component is also used to acquire a sample image of the sample to be tested, and obtain the detection result of the sample to be tested based on the sample image.

[0015] This application provides a quality control card and a hematology analyzer. The quality control card includes a first plate and a pattern layer. The first plate has at least one detection area, and the pattern layer is disposed in the detection area. The pattern layer includes a cell pattern composed of a plurality of quality control cells arranged in a proportional relationship with the size of real blood cells. Therefore, this application can perform calibration tests on the hematology analyzer by setting a cell pattern corresponding to the size of real blood cells on the quality control card, eliminating the need to prepare real quality control samples. This reduces the preparation time and consumable consumption of real quality control samples, reduces or avoids the expiration date limitations caused by using real quality control samples, and improves the quality control efficiency of the hematology analyzer. Attached Figure Description

[0016] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0017] Figure 1 This is a schematic diagram of the structure of the first embodiment of the quality control card provided in this application;

[0018] Figure 2 This is a schematic diagram of the structure of the second embodiment of the quality control card provided in this application;

[0019] Figure 3 This is a structural schematic diagram of the third embodiment of the quality control card provided in this application.

[0020] In the diagram, 10 is the quality control card; 11 is the first plate; 110 is the detection area; 111 is the first detection area; 112 is the second detection area; 113 is the third detection area; 12 is the pattern layer; 121 is the first pattern layer; 122 is the second pattern layer; 123 is the third pattern layer; 124 is the red blood cell image; 125 is the white blood cell image; 126 is the platelet image; and 13 is the protective layer. Detailed Implementation

[0021] The present application will now be described in further detail with reference to the accompanying drawings and embodiments. It should be particularly noted that the following embodiments are for illustrative purposes only and do not limit the scope of the application. Similarly, the following embodiments are only some, not all, embodiments of the present application, and all other embodiments obtained by those skilled in the art without inventive effort are within the scope of protection of the present application.

[0022] In this document, the term "embodiment" means that a particular feature, structure, or characteristic described in connection with an embodiment may be included in at least one embodiment of this application. The appearance of this phrase in various places throughout the specification does not necessarily refer to the same embodiment, nor is it a mutually exclusive, independent, or alternative embodiment. It will be explicitly and implicitly understood by those skilled in the art that the embodiments described herein can be combined with other embodiments.

[0023] In the description of this application, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "setting," "connection," and "linking" should be interpreted broadly. For example, they can refer to fixed connections, detachable connections, or integral connections; they can be mechanical connections or electrical connections; they can be direct connections or connections separated by an intermediate medium. For those skilled in the art, if directional indicators (such as up, down, left, right, front, back, etc.) are involved in the embodiments of this application, these directional indicators are only used to explain the relative positional relationships and movement of the components in a specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indicators will also change accordingly.

[0024] This application first proposes a quality control card for a blood cell analyzer. The blood cell analyzer is used to detect the quality control cells on the quality control card using cell imaging, or the blood cell analyzer is used to detect the blood cells of the test sample on the test card using cell imaging. The test sample can be a blood cell sample that has undergone simple pretreatment followed by labeling, staining, or fluorescence treatment, or it can be a blood cell sample that has only undergone simple pretreatment. No specific limitation is made here.

[0025] Please see Figure 1 and Figure 2 , Figure 1 This is a schematic diagram of the structure of the first embodiment of the quality control card provided in this application. Figure 2 This is a structural schematic diagram of the second embodiment of the quality control card provided in this application. Figure 1 and Figure 2 As shown, in this embodiment, the quality control card 10 includes a first plate 11 and a pattern layer 12.

[0026] Specifically, the first plate 11 is provided with at least one detection area 110; the pattern layer 12 is disposed in the detection area 110, and the pattern layer 12 includes a cell pattern formed by a plurality of quality control cells; the size of the quality control cells is proportional to the size of real blood cells.

[0027] The detection area 110 may be a region defined on the first plate 11 for setting the pattern layer 12, and / or the blood cell analyzer may include a detection component for acquiring images of the detection area 110 of the quality control card 10, i.e., the range of the detection area 110 of the quality control card 10 corresponds to the acquisition range of the detection component. In a possible implementation, the pattern layer 12 may be printed onto the detection area 110, for example, the pattern layer 12 may be formed on the first plate 11 by microprinting. When multiple detection areas 110 are provided on the first plate 11, the multiple detection areas 110 can be arranged in a preset pattern on the first plate 11. For example, the multiple detection areas 110 can be arranged in a straight line along a preset direction on the first plate 11, so that the detection components of the blood cell analyzer can sequentially acquire images of the pattern layer 12 of each detection area 110. Alternatively, the multiple detection areas 110 can be arranged in triangles, squares, polygons, or other shapes to improve the rationality of the layout of the detection areas 110 on the first plate 11 and reduce the area occupied by the detection areas 110 on the first plate 11.

[0028] Furthermore, the real blood cells in this embodiment can be understood as blood cells in a real blood sample. The size of the quality control cells on the cell pattern is proportional to the size of the real blood cells. The proportional relationship includes, but is not limited to: the size of the quality control cells being directly proportional to the size of the real blood cells, the size of the quality control cells being inversely proportional to the size of the real blood cells, and the size of the quality control cells being equal to the size of the real blood cells. For example, an image acquisition device such as a high-precision camera can be used to acquire an image of the real blood cell sample on the plate to obtain a real blood cell image. The cell pattern described above can be obtained by printing a proportionally enlarged image of the real blood cells onto the first plate 11, which can effectively improve the printing accuracy of the blood cell image; or, by printing a proportionally reduced image of the real blood cells onto the first plate 11, a larger number of quality control cells can be printed on the first plate 11 of the same size; or, by printing the real blood cell image proportionally (e.g., 1:1 or n:n) onto the first plate 11 to obtain the cell pattern described above. The aforementioned real blood cell images can be the original images of real blood cell samples acquired by the image acquisition device, or they can be stitched images obtained by segmenting, splicing, and arranging the original images. No specific limitation is made here.

[0029] In this embodiment, the first plate 11 of the quality control card 10 is provided with at least one detection area 110, and a pattern layer 12 is disposed in the detection area 110. The pattern layer 12 includes a cell pattern formed by a plurality of quality control cells arranged in a proportional relationship with the size of real blood cells. Therefore, this embodiment can perform calibration tests of the blood cell analyzer by setting a cell pattern corresponding to the size of real blood cells on the quality control card 10, without the need to prepare real quality control samples, reducing the preparation time of quality control samples and the consumption of consumables when preparing quality control samples, reducing or avoiding the expiration date limitation caused by the use of real quality control samples, and improving the quality control efficiency of the blood cell analyzer.

[0030] In one embodiment, the first plate 11 includes at least two detection zones 110, and the two detection zones 110 correspond to different types of quality control cells.

[0031] Specifically, the first plate 11 may have at least two detection zones 110, and the cell types of the quality control cells corresponding to each detection zone 110 are different. For example, blood cells may typically include red blood cells, white blood cells, and platelets, and the quality control cells of the two detection zones 110 may be any two of the aforementioned red blood cells, white blood cells, and platelets.

[0032] Therefore, this embodiment can further improve the quality control efficiency of the blood cell analyzer by setting at least two detection zones 110 on a quality control sheet to achieve calibration testing of at least two types of quality control cells through a single quality control sheet.

[0033] Optionally, please see Figure 3 , Figure 3 This is a structural schematic diagram of the third embodiment of the quality control card 10 provided in this application. Figure 3 As shown, in one embodiment, the first plate 11 includes a first detection area 111, a second detection area 112, and a third detection area 113. The quality control card 10 includes a first pattern layer 121, a second pattern layer 122, and a third pattern layer 123. The first pattern layer 121 is disposed in the first detection area 111, the second pattern layer 122 is disposed in the second detection area 112, and the third pattern layer 123 is disposed in the third detection area 113. The first pattern layer 121 is printed with a red blood cell image 124 formed by a plurality of red blood cells, the second pattern layer 122 is printed with a white blood cell image 125 formed by a plurality of white blood cells, and the third pattern layer 123 is printed with a platelet image 126 formed by a plurality of platelets.

[0034] Specifically, the first plate 11 is provided with a first detection area 111, a second detection area 112, and a third detection area 113. The first detection area 111 corresponds to the first pattern layer 121, the second detection area 112 corresponds to the second pattern layer 122, and the third detection area 113 corresponds to the third pattern layer 123. The control cells on the first pattern layer 121 are red blood cells, the control cells on the second pattern layer 122 are white blood cells, and the control cells on the third pattern layer 123 are platelets. Therefore, the quality control card 10 of this embodiment can simultaneously perform calibration tests on three types of blood cells, further improving the quality control efficiency of the blood cell analyzer.

[0035] In another embodiment, the first plate 11 includes a first detection area 111, a second detection area 112, and a third detection area 113. The quality control card 10 includes a first pattern layer 121, a second pattern layer 122, and a third pattern layer 123. The first pattern layer 121 is disposed in the first detection area 111, the second pattern layer 122 is disposed in the second detection area 112, and the third pattern layer 123 is disposed in the third detection area 113. The quality control cells on the first pattern layer 121, the second pattern layer 122, and the third pattern layer 123 have the same cell type, and the number of quality control cells on the first pattern layer 121, the second pattern layer 122, and the third pattern layer 123 increases progressively.

[0036] Specifically, the quality control cells on the first pattern layer 121, the second pattern layer 122, and the third pattern layer 123 have the same cell type. For example, the quality control cells on the first pattern layer 121, the second pattern layer 122, and the third pattern layer 123 can be any of red blood cells, white blood cells, and platelets. The number of quality control cells in the first pattern layer 121, the second pattern layer 122, and the third pattern layer 123 increases progressively, so that the number of cells represented by the cell patterns on the first pattern layer 121, the second pattern layer 122, and the third pattern layer 123 can be distributed within three ranges. The quality control card 10 can simultaneously perform calibration tests on blood cells within three ranges of cell counts.

[0037] The cell counts of the quality control cells in the first pattern layer 121, second pattern layer 122, and third pattern layer 123 can be selected based on the normal range of blood cell counts. For example, when the normal range of blood cell counts is between A and B (A being the lower limit and B the upper limit), the cell count of the quality control cells in the first pattern layer 121 can be close to or slightly less than A, so that the quality control cells in the first pattern layer 121 can be used to calibrate the accuracy of the blood cell analyzer in low-concentration samples. The cell count of the quality control cells in the second pattern layer 122 is between A and B; for example, the cell count of the quality control cells in the second pattern layer 122 can be the median of the normal range, so that the quality control cells in the second pattern layer 122 can be used to calibrate the accuracy of the blood cell analyzer in routine samples. The cell count of the quality control cells in the third pattern layer 123 can be close to or slightly greater than B, so that the quality control cells in the third pattern layer 123 can be used to calibrate the accuracy of the blood cell analyzer in high-concentration samples.

[0038] In this way, the quality control card 10 of this embodiment can simultaneously perform calibration tests on blood cells of three concentrations of the same cell type, further improving the quality control efficiency of the blood cell analyzer.

[0039] In one embodiment, the quality control card 10 further includes a protective layer 13, with the cell pattern located between the first plate 11 and the protective layer 13.

[0040] Specifically, the protective layer 13 can be one of a glass layer, a plastic layer, a silicone layer, a transparent film layer, a protective coating, etc., and the protective layer 13 is disposed on the side of the pattern layer 12 away from the first plate 11. The protective layer 13 of the quality control card 10 is used to protect the cell pattern to reduce or avoid the decrease in cell pattern accuracy caused by bumps, abrasions, etc. during transportation and handling, so as to ensure the detection accuracy of the blood cell analyzer.

[0041] In a possible implementation, the protective layer 13 may cover only the pattern layer 12; or, the protective layer 13 may include a first layer and a second layer connected together, the first layer covering the pattern layer 12 and the second layer being attached to the first plate 11 to provide full protection for the side of the first plate 11 closest to the cell pattern.

[0042] Optionally, the protective layer 13 is a transparent layer, and an anti-reflective coating is provided on the protective layer 13.

[0043] Specifically, the protective layer 13 is a transparent layer, allowing light to pass through and illuminate the pattern layer 12. An anti-reflective coating is provided on the protective layer 13. This coating reduces light reflection through the principles of destructive interference and refractive index gradient modulation, thereby increasing the light transmittance through the protective layer 13. The detection components of the blood cell analyzer may include an image acquisition unit and a light source. The light source provides transmitted light to the quality control card 10, illuminating the cell pattern on the quality control card 10. This allows light to pass directly into the objective lens after passing through the quality control card 10, improving the clarity of the quality control image acquired by the image acquisition unit.

[0044] In this embodiment, the quality control card 10 reduces light reflection on the surface of the protective layer 13 and increases light transmittance by setting an anti-reflective coating on the protective layer 13, thereby improving the clarity of the quality control image acquired by the image acquisition device and thus improving the detection accuracy of the blood cell analyzer.

[0045] In one embodiment, the first plate 11 includes at least two detection zones 110; real blood cells include abnormal blood cells, the size of the control cells in the cell pattern on at least one detection zone 110 is proportional to the size of the abnormal blood cells, and / or, the number of control cells in the cell pattern on at least one detection zone 110 is proportional to the number of abnormal blood cells, and / or, the shape of the control cells in the cell pattern on at least one detection zone 110 is the same as the shape of the abnormal blood cells.

[0046] Specifically, the first plate 11 includes at least two detection areas 110. The size and / or number of control cells in each detection area 110 are proportional to the abnormal blood cells, and / or the shape of the control cells in the cell pattern of the control cells in each detection area 110 is the same as the shape of the abnormal blood cells. The proportional relationship can include direct proportionality, inverse proportionality, and equal proportionality. Direct proportionality can be understood as printing abnormal blood cells at a proportionally enlarged size and / or cell number to obtain control cells; inverse proportionality can be understood as printing abnormal blood cells at a proportionally reduced size and / or cell number to obtain control cells; and equal proportionality can be understood as printing abnormal blood cells at a proportional (e.g., 1:1 or n:n) ratio to obtain control cells.

[0047] Furthermore, abnormal blood cells can be understood as blood cells defined as abnormal samples in a real blood sample. For example, when the cell type of the quality control cells is red blood cells, abnormal samples include, but are not limited to: abnormal samples with red blood cell volume greater than a first preset value (i.e., abnormal red blood cells are large red blood cells), abnormal samples with red blood cell volume less than a second preset value (i.e., abnormal red blood cells are small red blood cells), abnormal samples with red blood cell count greater than a third preset value (i.e., increased red blood cell count), abnormal samples with red blood cell count less than a fourth preset value (i.e., decreased red blood cell count), and abnormal samples with abnormal red blood cell shape (i.e., abnormal red blood cells are atypical red blood cells). As another example, when the cell type of the quality control cells is white blood cells, abnormal samples include, but are not limited to: abnormal samples with white blood cell count greater than a fifth preset value (i.e., increased white blood cell count), abnormal samples with white blood cell count less than a sixth preset value (i.e., decreased white blood cell count), and abnormal samples with abnormal white blood cell shape (e.g., toxic particles, Dürer bodies, or immature cells). For example, when the cell type of the quality control cell is platelets, abnormal samples include, but are not limited to: abnormal samples with a platelet count greater than the seventh preset value (i.e., platelet enlargement), abnormal samples with a platelet count less than the eighth preset value (i.e., platelet decrease), and abnormal samples with abnormal platelet shape (e.g., giant platelets).

[0048] Therefore, through the above method, the quality control card 10 of this embodiment can obtain corresponding quality control cells by printing at least one of the size, number and shape of abnormal blood cells in a proportional relationship, so that the quality control cells of this embodiment can simulate the abnormality of the size, number or shape of abnormal blood cells, so as to realize the calibration test of multiple abnormal blood cells and improve the quality control efficiency and accuracy of the blood cell analyzer.

[0049] In one embodiment, the size of the quality control cells is the same as that of real blood cells; the first plate 11 is a transparent plate, and the pattern layer 12 has a light transmittance of a preset threshold.

[0050] Specifically, in this embodiment, the size of the control cells in the quality control card 10 is the same as the size of real blood cells; that is, the control cells in the quality control card 10 are obtained by printing them proportionally to real blood cells. In this embodiment, the first plate 11 is a transparent plate, and the pattern layer 12 has a preset threshold transmittance, allowing light to pass through the first plate 11 and the pattern layer 12. The detection component of the blood cell analyzer can be equipped with a light source below the quality control card 10, so that the light source passes through the first plate 11 and enters the pattern layer 12 of the quality control card 10, allowing the image acquisition component to acquire images of the quality control card 10 under sufficient light; and / or, the detection component of the blood cell analyzer can be equipped with a corresponding image acquisition component below the quality control card 10, so that the image acquisition component can acquire the cell pattern of the pattern layer 12 through the transparent plate of the first plate 11.

[0051] This application also proposes a blood cell analyzer, which is used to calibrate and test the quality control card 10 of any of the above embodiments to obtain quality control results.

[0052] Specifically, the detection component of the blood cell analyzer acquires images of the quality control card 10 through the image acquisition device to obtain quality control images. The blood cell analyzer is also used to obtain corresponding quality control results based on the quality control images. The quality control results can be used to determine whether the blood cell analyzer's detection capability for different types of samples meets the standards, thereby improving the accuracy of the blood cell analyzer's detection results.

[0053] Therefore, the blood cell analyzer in this embodiment calibrates the cell pattern on the pattern layer 12 on the quality control card 10 without the need to create a real quality control sample. This reduces the time required to create the quality control sample and the consumption of consumables, thereby reducing or avoiding the expiration date limitations caused by using a real quality control sample. This effectively improves the quality control efficiency of the blood cell analyzer. Furthermore, using the quality control image on the quality control card 10 for calibration testing can accurately reproduce the characteristics of real blood cells, further improving the consistency and stability of the blood cell analyzer calibration.

[0054] In one embodiment, the blood cell analyzer includes a carrier component and a detection component.

[0055] Specifically, the carrier component is used to receive the test card, which contains the sample to be tested, and is also used to receive the quality control card 10; the detection component is connected to the carrier component and is used to acquire the quality control image of the cell pattern of the quality control card 10, and obtain the quality control result of the blood cell analyzer based on the quality control image; the detection component is also used to acquire the sample image of the sample to be tested, and obtain the detection result of the sample to be tested based on the sample image.

[0056] The sample to be tested can be understood as a blood sample that needs to be tested. The test card is a plate that carries the sample to be tested, and the blood cells in the sample on the test card are the blood cells to be tested. The detection component is used to acquire a quality control image of the cell pattern on the quality control card 10, and obtain the quality control result of the blood cell analyzer based on the quality control image. The quality control result is used to indicate whether the blood cell analyzer's ability to detect the corresponding type of cell pattern on the quality control card 10 meets the standard. The detection component is also used to acquire a sample image of the sample to be tested, and obtain the detection result of the sample to be tested based on the sample image. The detection result is used to indicate the blood cell-related parameters of the sample to be tested, such as the volume and number of red blood cells, white blood cells, and platelets.

[0057] Optionally, the detection card includes a second plate and a detection slot, the detection slot being disposed on the second plate and used to contain the sample solution to be tested. The detection component is used to acquire images of the sample solution in the detection slot to obtain the image data of the sample to be tested and to obtain the detection result of the sample to be tested based on the image data.

[0058] The pattern layer 12 has the same size as the cross-sectional size of the detection groove. The pattern layer 12 is positioned on the first plate 11 of the quality control card 10 as the detection groove is positioned on the second plate of the detection card. The pattern layer 12 of the quality control card 10 can correspond to the sample to be tested on the detection card, so that the cell pattern of the quality control card 10 can be used to simulate the distribution of real quality control samples on the detection card, thereby further improving the detection accuracy of the quality control card 10.

[0059] Optionally, the detection area of ​​the quality control card 10 is printed with a quality control image, the detection area of ​​the test card contains the sample to be tested, and the size of the detection area of ​​the quality control card 10 is the same as the size of the detection area of ​​the test card; and / or, the external dimensions of the quality control card 10 are the same as the external dimensions of the test card.

[0060] Specifically, the detection area of ​​the quality control card 10 is used to print quality control images, and the detection area of ​​the detection card is used to hold the sample to be tested. The detection area of ​​the quality control card 10 can be a first area, and the detection area of ​​the detection card can be a second area. The size of the first area and the size of the second area are the same, and / or the position of the first area on the quality control card 10 and the position of the second area on the detection card are the same. Furthermore, the external dimensions of the quality control card 10 and the external dimensions of the detection card are the same, allowing the detection components of the blood cell analyzer to directly detect the detection area of ​​the quality control card 10 without adjusting the detection position or other related parameters.

[0061] The above description is merely an embodiment of this application and does not limit the patent scope of this application. Any equivalent structural or procedural transformations made using the content of this application's specification and drawings, or direct or indirect applications in other related technical fields, are similarly included within the patent protection scope of this application.

Claims

1. A quality control card for a hematology analyzer, characterized in that, The quality control card includes: The first plate has at least one detection area; A pattern layer is disposed in the detection area, the pattern layer comprising a cell pattern formed by a plurality of quality control cells arranged in proportion to the size of real blood cells.

2. The quality control card according to claim 1, characterized in that, The first plate includes at least two detection zones, and the quality control cells corresponding to the at least two detection zones are of different types.

3. The quality control card according to claim 2, characterized in that, The first plate includes a first detection area, a second detection area, and a third detection area. The quality control card includes a first pattern layer, a second pattern layer, and a third pattern layer. The first pattern layer is disposed in the first detection area, the second pattern layer is disposed in the second detection area, and the third pattern layer is disposed in the third detection area. The first pattern layer is printed with an image of red blood cells arranged in a plurality of red blood cells. The second pattern layer is printed with an image of white blood cells arranged in a plurality of white blood cells. The third pattern layer is printed with an image of platelets arranged in a plurality of platelets.

4. The quality control card according to claim 1, characterized in that, The quality control card also includes a protective layer, and the cell pattern is located between the first plate and the protective layer.

5. The quality control card according to claim 4, characterized in that, The protective layer is a transparent layer, and an anti-reflective coating is provided on the protective layer.

6. The quality control card according to claim 1, characterized in that, The first plate includes a first detection area, a second detection area, and a third detection area. The quality control card includes a first pattern layer, a second pattern layer, and a third pattern layer. The first pattern layer is disposed in the first detection area, the second pattern layer is disposed in the second detection area, and the third pattern layer is disposed in the third detection area. The quality control cells on the first pattern layer, the second pattern layer, and the third pattern layer have the same cell type, and the number of quality control cells on the first pattern layer, the second pattern layer, and the third pattern layer increases progressively.

7. The quality control card according to claim 1, characterized in that, The first plate includes at least two detection zones; the real blood cells include abnormal blood cells, the size of the control cells in the cell pattern on at least one of the detection zones is proportional to the size of the abnormal blood cells, and / or, the number of control cells in the cell pattern on at least one of the detection zones is proportional to the number of abnormal blood cells, and / or, the shape of the control cells in the cell pattern on at least one of the detection zones is the same as the shape of the abnormal blood cells.

8. The quality control card according to claim 1, characterized in that, The size of the quality control cells is consistent with the size of real blood cells; The first plate is a transparent plate, and the pattern layer has a light transmittance of a preset threshold.

9. A blood cell analyzer, characterized in that, The blood cell analyzer is used to calibrate and test the quality control card as described in any one of claims 1-8 to obtain quality control results.

10. The blood cell analyzer according to claim 9, characterized in that, The blood cell analyzer includes: A carrier component is used to receive a test card, the test card containing a sample to be tested, and also to receive the quality control card; A detection component is connected to the carrier component. The detection component is used to acquire quality control images of cell patterns on the quality control card and obtain the quality control results of the blood cell analyzer based on the quality control images. The detection component is also used to acquire sample images of the sample to be tested, and to obtain the detection results of the sample to be tested based on the sample images.

Images