A titration device for the synthesis of sulfazecine

Abstract

This utility model discloses a titration device for the synthesis and processing of azole sulfate, including an automatic potentiometric titration host and an electromagnetic stirring table located on the left side of the automatic potentiometric titration host. A metering tube pressure ring is set at the top of the automatic potentiometric titration host, and a titration metering tube is inserted and fixed in the metering tube pressure ring. An adjustment knob is set at the center of the front end of the electromagnetic stirring table. By adding leakage absorption and protection devices on the left side of the electromagnetic stirring table and the upper side of the automatic potentiometric titration host, rectangular suction hood A is aligned with the cup lid and the connection between the burette and the delivery tube, and rectangular suction hood B is aligned with the titration metering tube, the device accurately covers the leakage points and can capture reagent volatilization and leakage caused by pressure fluctuations, seal aging, etc. in the first time, avoiding the diffusion of acidic substances and azole volatiles. The vertical and horizontal support plates construct a U-shaped space protection, and the double-hood, double-dimensional suction forms a semi-enclosed interception system, effectively absorbing various leaks and strengthening the comprehensiveness of control.

Description

Technical Field

[0001] This utility model belongs to the technical field of fine chemical synthesis, specifically relating to a titration device for the synthesis and processing of azole sulfate. Background Technology

[0002] The synthesis of azole sulfate requires precise control of the raw material ratio and reaction endpoint. The titration device monitors the changes in parameters such as ion concentration and pH of the system by quantitatively adding standard solutions, providing core data support for "precise addition of raw materials - control of reaction process - verification of product purity". It is the foundation for ensuring the stability of the synthesis process and the compliance of product quality. In the azole sulfate synthesis process, the titration operation is a key link in controlling the reaction process and ensuring product quality. However, in practical applications, traditional titration devices face prominent problems such as leakage risks that threaten safety and the environment, and uneven reaction system affecting titration accuracy.

[0003] The connection points between the burette and the delivery tube, as well as the burette itself, are prone to leakage of azole sulfate synthesis reagent (containing acidic components and azole volatiles) due to long-term vibration and aging of seals. Acidic substances can corrode equipment and contaminate work surfaces; inhaled azole volatiles pose health risks; and if they diffuse into the operating environment, they may also create flammable and explosive hazards. Furthermore, the sealing edges of the titration cup and lid may experience minor leaks due to stirring vibrations and reagent corrosion. Leaked material can adhere to equipment surfaces, accumulating and causing corrosion, and the continued diffusion of volatiles can damage laboratory air quality and increase occupational health risks for personnel. Utility Model Content

[0004] The purpose of this invention is to provide a titration apparatus for the synthesis and processing of azole sulfate, in order to solve the problems mentioned in the background art, such as the easy leakage of reagents containing acidic components and azole volatiles at the connection between the metering tube and the delivery tube and the burette due to vibration and aging of the seal, which corrodes the equipment, contaminates the work surface, and the volatiles endanger health and even cause flammable and explosive risks. In addition, the sealing edge of the titration cup and the cup lid may also leak slightly due to vibration and reagent corrosion.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a titration device for the synthesis and processing of azole sulfate, comprising an automatic potentiometric titration host and an electromagnetic stirring table disposed on the left side of the automatic potentiometric titration host. A metering tube pressure ring is provided at the top of the automatic potentiometric titration host, and a titration metering tube is inserted and fixed in the metering tube pressure ring. An adjustment knob is provided at the center of the front end of the electromagnetic stirring table, and the adjustment knob can adjust the electromagnetic stirring power by rotating clockwise and counterclockwise. A titration cup is placed at the center of the top of the electromagnetic stirring table, and a cup lid is sealed to the outside of the opening at the top of the titration cup. A burette is inserted and sealed at the center of the cup lid, and the burette is inserted into the inside of the titration cup. A delivery tube is connected to the top of the burette and the top of the titration metering tube. Leakage absorption and protection devices are provided on the left side of the electromagnetic stirring table and on the upper side of the automatic potentiometric titration host.

[0006] Preferably, the leakage absorption and protection device includes a U-shaped mounting base, a vertical support plate, a rectangular suction hood A, a horizontal support plate, and a rectangular suction hood B. The U-shaped mounting base, with its opening facing right, is fitted onto the front and rear sides and the left side of the electromagnetic stirring table. Both the U-shaped mounting base and the electromagnetic stirring table can be placed directly on the work surface. A vertical support plate is vertically fixed to the top left end of the U-shaped mounting base. A horizontal support plate is fixed to the top right end of the vertical support plate. The vertical support plate is located to the left of the electromagnetic stirring table and the titration cup. The horizontal support plate is located above the automatic potentiometric titration host. A rectangular suction hood A is inserted and fixed at the center of the left end of the vertical support plate. The right end of the rectangular suction hood A is open, and the right end opening of the rectangular suction hood A is aligned with the cup lid and the connection between the burette and the delivery pipe. A rectangular suction hood B is inserted and fixed to the right side of the top center of the horizontal support plate. The rectangular suction hood B is open for titration, and the bottom opening of the rectangular suction hood B is aligned with the titration metering tube.

[0007] Preferably, the leakage absorption and protection device further includes an air pump, an air inlet, and an air supply pipe. An air pump is fixed on the left side of the center of the outer wall at the top of the horizontal support plate. An air inlet is provided on both the left and right sides of the lower side of the center of the air pump. Both air inlets are connected to rectangular suction hood A and rectangular suction hood B through air supply pipes. When the air pump is running, it can draw in external air through rectangular suction hood A and rectangular suction hood B through the connection of the air supply pipes.

[0008] Preferably, the leakage absorption and protection device further includes an absorption filter box, an air outlet, and fixed support rods. The absorption filter box is disposed above the air pump. Multiple fixed support rods are equidistantly connected between the air pump and the absorption filter box near the edge. The absorption filter box is fixed above the air pump by the multiple fixed support rods. An air outlet is disposed at the center of the top of the air pump. The top of the air outlet is connected to the absorption filter box.

[0009] Preferably, the air outlet is connected to the inside of the absorption filter box, the top of the absorption filter box is densely covered with air outlet holes, and a mesh frame is horizontally fixed on the lower side of the center of the absorption filter box, on which a mixture of diatomaceous earth and activated carbon is placed.

[0010] Preferably, the automatic potentiometric titration host has a replacement window inside the right end, and a magnetic window protective plate is magnetically fixed inside the opening of the right end of the replacement window. The automatic potentiometric titration host has a solvent bottle and an electrode storage tube inside, and the solvent bottle and electrode storage tube can be replaced through the replacement window after the magnetic window protective plate is opened.

[0011] Preferably, the upper half of the front end of the automatic potentiometric titration host is set with an inclined surface, and a display screen is set inside the outer wall of the inclined surface of the front end of the automatic potentiometric titration host, and multiple control buttons are set at equal intervals below the display screen.

[0012] Preferably, an electrode support is vertically fixed at the rear side of the top center of the electromagnetic stirring table, and the electrode support is located at the rear side of the titration cup. The electrode support and the cup lid are fixedly connected by an electrode holder, and a pressure relief valve is also provided at the front side of the top center of the cup lid.

[0013] Compared with the prior art, this utility model provides a titration device for the synthesis and processing of azole sulfate, which has the following advantages:

[0014] This invention adds a novel leakage absorption and protection device to the left side of the electromagnetic stirring table and the upper side of the automatic potentiometric titration host. The device uses rectangular suction hood A to be aligned with the connection between the cup lid, the burette and the delivery tube, and rectangular suction hood B to be aligned with the titration metering tube, precisely covering the leakage points of the device. In the azole sulfate synthesis titration, if reagent volatilization and leakage occur in these parts due to pressure fluctuations, seal aging, etc., the suction hood can capture them immediately, preventing acidic substances and azole volatiles from spreading to the operating environment, reducing safety hazards from the source. The vertical support plate and horizontal support plate of the device form a U-shaped space protection. The two-dimensional suction of rectangular suction hood A and rectangular suction hood B can form a semi-enclosed interception system around the core titration area. Whether the leakage is dripping downwards or volatilizing upwards, it can be effectively sucked up, enhancing the comprehensiveness of leakage control.

[0015] Furthermore, the device absorbs a mixture of diatomaceous earth and activated carbon in the filter box, utilizing the adsorption properties of diatomaceous earth and the microporous structure of activated carbon to adsorb and neutralize the pumped-out leaks. For example, acidic substances are adsorbed and neutralized by diatomaceous earth, while volatile organic compounds are trapped by activated carbon. After purification, the gas is discharged from the vent, reducing pollution to laboratory air and lowering the risk of operators inhaling harmful substances. Ultimately, a closed loop from pumping to purification to discharge is achieved between the pump, the suction hood, and the filter box. Compared to fugitive emissions or simple collection, this process achieves active collection and purification of leaked substances, meeting the requirements for clean production in chemical synthesis. Attached Figure Description

[0016] Figure 1 This is a front-view three-dimensional structural diagram of a titration device for the synthesis and processing of azole sulfate according to the present invention.

[0017] Figure 2 This is a front view schematic diagram of a titration apparatus for the synthesis and processing of azole sulfate according to the present invention.

[0018] Figure 3 This is a front-view three-dimensional structural diagram of the leakage absorption and protection device of this utility model.

[0019] Figure 4 This is a front view schematic diagram of the leakage absorption and protection device of this utility model.

[0020] In the diagram: 1. Automatic potentiometric titration main unit; 2. Control buttons; 3. Display screen; 4. Electromagnetic stirring table; 5. Adjustment knob; 6. Titration cup; 7. Cup lid; 8. Burette; 9. Delivery tube; 10. Electrode support; 11. Leakage absorption protection device; 12. Metering tube pressure ring; 13. Titration metering tube; 14. Replacement window; 15. Magnetic window protection plate; 16. U-shaped mounting base; 17. Vertical support plate; 18. Rectangular suction hood A; 19. Air pump; 20. Absorption filter box; 21. Air inlet; 22. Air supply duct; 23. Horizontal support plate; 24. Rectangular suction hood B; 25. Air outlet; 26. Fixed support rod. Detailed Implementation

[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0022] This utility model provides, for example Figure 1-4The illustrated titration apparatus for the synthesis of azole sulfate includes an automatic potentiometric titration main unit 1 and an electromagnetic stirring table 4 located on the left side of the automatic potentiometric titration main unit 1. A metering tube clamping ring 12 is located at the top of the automatic potentiometric titration main unit 1, and a titration metering tube 13 is inserted and fixed in the metering tube clamping ring 12. A replacement window 14 is located inside the right end of the automatic potentiometric titration main unit 1, and a magnetically attached window protective plate 15 is magnetically fixed inside the opening of the right end of the replacement window 14. A solvent bottle and an electrode storage tube are located inside the automatic potentiometric titration main unit 1, and the solvent bottle and electrode storage tube can be replaced through the replacement window 14 after the magnetically attached window protective plate 15 is opened. The upper half of the front end of the automatic potentiometric titration main unit 1 is sloped, and a display screen 3 is located inside the outer wall of the sloped front end of the automatic potentiometric titration main unit 1. Multiple control buttons 2 are equidistantly arranged below the display screen 3. The device is used for the titration of azole sulfate synthesis. In the titration process, the automatic potentiometric titration unit 1 is the core control unit. It operates based on electrochemical principles, precisely adding a standard solution of known concentration to the titration cup 6 via the burette 13. As the standard solution is continuously added, the ion concentration in the azole sulfate synthesis reaction system (such as acidic, alkaline, or redox environments) changes, causing a change in the potential of the electrodes (such as pH electrodes and redox electrodes). The unit collects the electrode potential signals in real time. When a significant abrupt change in potential occurs, it determines that the reaction has reached the stoichiometric point, which is the titration endpoint. Subsequently, based on the volume of standard solution consumed and combined with the pre-set stoichiometric relationship, the unit calculates the content of the analyte (such as the concentration of raw materials in the synthesis and parameters related to product purity), providing accurate quantitative data for the addition of raw materials, control of the reaction process, and inspection of product quality in the azole sulfate synthesis.

[0023] like Figure 1 and Figure 2As shown, an adjustment knob 5 is located at the center of the front end of the electromagnetic stirring table 4. Rotating the knob 5 clockwise or counterclockwise adjusts the electromagnetic stirring power. A titration cup 6 is placed at the center of the top of the electromagnetic stirring table 4. A lid 7 is sealed to the outside of the opening at the top of the titration cup 6. A burette 8 is inserted and sealed into the center of the lid 7, and the burette 8 is inserted inside the titration cup 6. A delivery tube 9 is connected to the top of the burette 8 and the top of the titration measuring tube 13. An electrode support 10 is vertically fixed to the rear side of the center of the top of the electromagnetic stirring table 4, and the electrode support 10 is located behind the titration cup 6. The electrode support 10 and the lid 7 are fixedly connected by an electrode holder. A pressure relief valve is also installed at the front of the core. The electromagnetic stirring table 4 uses a magnetic field to drive the stir bar inside the titration cup 6 to rotate, so that the solution inside the cup is in a turbulent state. During the titration of azole sulfate synthesis, on the one hand, stirring can make the standard solution and the test solution mix quickly and uniformly, avoid local concentration differences (such as local acid or base excess), ensure that the change of electrode potential can truly reflect the situation of the entire reaction system, and prevent misjudgment of the titration endpoint due to local reaction abnormalities. On the other hand, the synthesis reaction is sometimes accompanied by temperature and concentration changes. Stirring can accelerate heat transfer and material diffusion, maintain the thermodynamic and electrochemical equilibrium of the system, and make the signal acquisition of potentiometric titration more accurate.

[0024] like Figure 1 , Figure 3 and Figure 4 As shown, a leakage absorption protection device 11 is installed on the left side of the electromagnetic stirring table 4 and on the upper side of the automatic potentiometric titration host 1. The leakage absorption protection device 11 includes a U-shaped mounting base 16, a vertical support plate 17, a rectangular suction hood A18, a horizontal support plate 23, and a rectangular suction hood B24. The U-shaped mounting base 16, with its opening facing right, is fitted onto the front and rear sides and the left side of the electromagnetic stirring table 4. Both the U-shaped mounting base 16 and the electromagnetic stirring table 4 can be placed directly on the work surface. A vertical support plate 17 is vertically fixed to the top left end of the U-shaped mounting base 16, and a horizontal support plate 23 is fixed to the top right end of the vertical support plate 17. The support plate 23 and the vertical support plate 17 are located to the left of the electromagnetic stirring table 4 and the titration cup 6. The horizontal support plate 23 is located above the automatic potentiometric titration host 1. A rectangular suction hood A18 is inserted and fixed at the center of the left end of the vertical support plate 17. The right end of the rectangular suction hood A18 is open and aligned with the cup lid 7 and the connection between the burette 8 and the delivery tube 9. A rectangular suction hood B24 is inserted and fixed at the right side of the center of the top of the horizontal support plate 23. The rectangular suction hood B24 is open and aligned with the bottom opening of the rectangular suction hood B24.

[0025] like Figure 1 , Figure 3 and Figure 4As shown, the leakage absorption protection device 11 also includes an air pump 19, an air inlet 21, and an air supply pipe 22. The air pump 19 is fixed to the left side of the center of the outer wall at the top of the horizontal support plate 23. Air inlets 21 are provided at both ends of the lower side of the center of the air pump 19, and both air inlets 21 are connected to the rectangular suction hoods A18 and B24 via air supply pipes 22. When the air pump 19 is running, it can draw in external air through the rectangular suction hoods A18 and B24 via the connection of the air supply pipes 22. The rectangular suction hoods A18 and B24 utilize Bernoulli's principle to draw in external air. When the air pump 19 is running, a low-pressure zone is formed at the hood opening. Leaked volatiles (such as sulfuric acid mist and azole organic vapors) are drawn into the hood due to the ambient air pressure difference. Especially for the small leaks at the sealing edge of the titration cup 6 and the pipe connection in the synthesis of azole sulfate, the leaks can be confined to a small space by nearby suction and double hood coverage, preventing them from spreading to the operating environment. In addition, the air supply pipe 22 connects the suction hood and the air pump 19 to form a negative pressure transmission channel. When the airflow flows in the pipe, it follows the continuity equation, ensuring that the leaks are continuously and stably suctioned and will not escape due to airflow turbulence.

[0026] like Figure 1 , Figure 3 and Figure 4 As shown, the leakage absorption protection device 11 also includes an absorption filter box 20, an air outlet 25, and fixed support rods 26. The absorption filter box 20 is installed above the air pump 19. Multiple fixed support rods 26 are equidistantly connected between the air pump 19 and the absorption filter box 20 near the edge, and the absorption filter box 20 is fixed above the air pump 19 by the multiple fixed support rods 26. An air outlet 25 is provided at the center of the top of the air pump 19. The top of the air outlet 25 is connected to the absorption filter box 20 and communicates with the inside of the absorption filter box 20. The top of the absorption filter box 20 is densely covered with air outlet holes. A mesh frame is horizontally fixed on the lower side of the center of the inside of the absorption filter box 20, and diatomaceous earth is placed on the mesh frame. The mixture of diatomaceous earth and activated carbon utilizes the porous structure of diatomaceous earth, which exhibits capillary adsorption of acidic liquids or vapors. Simultaneously, the SiO2 in diatomaceous earth can undergo weak chemical reactions with acidic substances. Activated carbon, with its abundant micropores (pore sizes adapted to organic molecules), exhibits strong van der Waals adsorption of azole organic compounds. It traps volatile organic molecules through intermolecular forces, and the mesh structure supports the adsorbent, allowing the gas flow to pass evenly through the porous adsorption layer from below (similar to fixed-bed adsorption). This ensures sufficient contact between the gas and the adsorbent, prolonging the residence time and improving purification efficiency. The purified gas is then discharged through the vent, thus reducing the environmental and human health threats posed by acidic corrosion and organic toxicity during azole sulfate synthesis at the source.

[0027] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A titration apparatus for the synthesis and processing of azole sulfate, comprising an automatic potentiometric titration host (1) and an electromagnetic stirring table (4) disposed on the left side of the automatic potentiometric titration host (1), wherein a metering tube pressure ring (12) is provided at the top of the automatic potentiometric titration host (1), a titration metering tube (13) is inserted and fixed in the metering tube pressure ring (12), an adjustment knob (5) is provided at the center of the front end of the electromagnetic stirring table (4), the adjustment knob (5) can adjust the electromagnetic stirring power by rotating clockwise and counterclockwise, a titration cup (6) is placed at the center of the top of the electromagnetic stirring table (4), a cup lid (7) is sealed to the outside of the top opening of the titration cup (6), a burette (8) is inserted and sealed at the center of the cup lid (7), and the burette (8) is inserted into the titration cup (6), and a delivery tube (9) is connected to the top of the burette (8) and the top of the titration metering tube (13), characterized in that: Leakage absorption protection device (11) is provided on the left side of the electromagnetic stirring table (4) and on the upper side of the automatic potentiometric titration host (1); The leakage absorption and protection device (11) includes a U-shaped mounting base (16), a vertical support plate (17), a rectangular suction hood A (18), a horizontal support plate (23), and a rectangular suction hood B (24). The U-shaped mounting base (16) is sleeved on the front and rear sides and the left side of the electromagnetic stirring table (4) with its opening facing right. Both the U-shaped mounting base (16) and the electromagnetic stirring table (4) can be placed directly on the work surface. The vertical support plate (17) is vertically fixed to the top left side of the U-shaped mounting base (16), and the horizontal support plate (23) is fixed to the top right side of the vertical support plate (17). The vertical support plate (17) is located on the electromagnetic stirring table. (4) To the left of the titration cup (6), the horizontal support plate (23) is located above the automatic potentiometric titration host (1). A rectangular suction hood A (18) is inserted and fixed at the center of the left end of the vertical support plate (17). The right end of the rectangular suction hood A (18) is open, and the right end opening of the rectangular suction hood A (18) is aligned with the cup lid (7) and the connection between the burette (8) and the delivery tube (9). A rectangular suction hood B (24) is inserted and fixed at the right side of the center of the top of the horizontal support plate (23). The rectangular suction hood B (24) is open for titration, and the bottom opening of the rectangular suction hood B (24) is aligned with the titration metering tube (13).

2. The titration apparatus for the synthesis and processing of azole sulfate according to claim 1, characterized in that: The leakage absorption and protection device (11) also includes an air pump (19), an air inlet (21), and an air supply pipe (22). The air pump (19) is fixed on the left side of the center of the top outer wall of the horizontal support plate (23). The air pump (19) has an air inlet (21) on both the left and right sides of the lower side of the center. The two air inlets (21) are connected to the rectangular suction hood A (18) and the rectangular suction hood B (24) through the air supply pipe (22). When the air pump (19) is running, it can draw in external air through the rectangular suction hood A (18) and the rectangular suction hood B (24) through the connection of the air supply pipe (22).

3. The titration apparatus for the synthesis and processing of azole sulfate according to claim 2, characterized in that: The leakage absorption and protection device (11) further includes an absorption filter box (20), an air outlet (25), and a fixed support rod (26). The absorption filter box (20) is arranged above the air pump (19). Multiple fixed support rods (26) are equidistantly connected between the air pump (19) and the absorption filter box (20) near the edge. The absorption filter box (20) is fixed above the air pump (19) by multiple fixed support rods (26). An air outlet (25) is arranged at the center of the top of the air pump (19). The top of the air outlet (25) is connected to the absorption filter box (20).

4. The titration apparatus for the synthesis and processing of azole sulfate according to claim 3, characterized in that: The air outlet (25) is connected to the inside of the absorption filter box (20). The top of the absorption filter box (20) is densely covered with air outlet holes. A mesh frame is horizontally fixed on the lower side of the center of the absorption filter box (20). A mixture of diatomaceous earth and activated carbon is placed on the mesh frame.

5. The titration apparatus for the synthesis and processing of azole sulfate according to claim 1, characterized in that: The automatic potentiometric titration host (1) has a replacement window (14) inside its right end. A magnetic window protection plate (15) is magnetically fixed inside the opening of the right end of the replacement window (14). The automatic potentiometric titration host (1) has a solvent bottle and an electrode storage tube inside. After the magnetic window protection plate (15) is opened, the solvent bottle and the electrode storage tube can be replaced through the replacement window (14).

6. The titration apparatus for the synthesis and processing of azole sulfate according to claim 1, characterized in that: The upper half of the front end of the automatic potentiometric titration host (1) is set with an inclined surface, and a display screen (3) is set inside the outer wall of the inclined surface of the front end of the automatic potentiometric titration host (1). Multiple control buttons (2) are set at equal intervals below the display screen (3).

7. The titration apparatus for the synthesis and processing of azole sulfate according to claim 1, characterized in that: An electrode support (10) is vertically fixed at the rear side of the top center of the electromagnetic stirring table (4), and the electrode support (10) is located at the rear side of the titration cup (6). The electrode support (10) and the cup lid (7) are fixedly connected by an electrode frame. A pressure relief valve is also provided at the front side of the top center of the cup lid (7).

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