A mouse tail vein injection restraint device

Abstract

This utility model relates to the field of mouse tail vein injection experimental equipment, and discloses a mouse tail vein injection restraint device, including a base and a light-shielding central tube. Two supports are symmetrically arranged on the base. The two sides of the light-shielding central tube are rotatably connected to the supports. Openings are provided at both ends of the light-shielding central tube. A partition is fixedly provided at the top of the light-shielding central tube, and the partition has several ventilation holes. A baffle assembly is provided at the bottom of the light-shielding central tube, and the baffle assembly has a gap for exposing the mouse tail. A hollow ventilation plug is provided inside the light-shielding central tube, and the ventilation plug and the partition are movably connected along the axial direction of the light-shielding central tube. An observation lamp is detachably installed on the outer wall of the light-shielding central tube. This utility model aims to improve the reliability of mouse restraint and reduce the stress response of mice during the restraint process.

Description

Technical Field

[0001] This utility model relates to the field of experimental equipment for mouse tail vein injection, and specifically to a mouse tail vein injection restraint device. Background Technology

[0002] Mice are commonly used laboratory animals in biomedical research, and tail vein injection is a routine technique for drug delivery, blood sampling, and contrast agent injection. Because mouse tail veins are thin and densely covered by skin, the injection process requires extremely high operational stability and precision. Furthermore, mice are small and agile, and may exhibit fear or violent struggle during injection for various reasons. To ensure successful injection and reduce animal stress, mice must be reliably restrained using specialized restraint devices. This not only fully exposes the tail vessels and maintains them at a suitable operating angle but also prevents the mice from biting or scratching the operator, reducing personnel safety risks.

[0003] Currently, most common tail vein injection restraint devices use a cylindrical structure to restrain the mouse's body. They typically consist of a fixed support and a rigid tube to hold the mouse. The mouse's head and body are fixed within the tube, with a through-hole at one end exposing the tail. The mouse's tail needs to be manually extended through this hole for injection. However, this method has several drawbacks. First, mice are nocturnal and prefer dimly lit environments, while the rigid tube is usually made of a non-light-blocking material. The mouse inside is easily stimulated by external light, causing fear and restlessness. Second, existing restraint devices expose the tail through a single through-hole, the diameter of which is only slightly larger than the tail's diameter. During the procedure, the mouse's tail must be manually aligned with the through-hole and pulled out. This manual intervention can cause the mouse to struggle violently, leading to restraint failure. Utility Model Content

[0004] The present invention aims to provide a mouse tail vein injection restraint device to improve the reliability of mouse restraint and reduce the stress response of mice during the restraint process.

[0005] To achieve the above objectives, the present invention adopts the following technical solution: A mouse tail vein injection restraint device includes a base and a light-shielding central tube. Two supports are symmetrically arranged on the base. The two sides of the light-shielding central tube are rotatably connected to the supports. A silicone pad is provided on the inner wall of the light-shielding central tube. Openings are provided at both ends of the light-shielding central tube. A partition is fixedly provided at the top of the light-shielding central tube. The partition has several ventilation holes. A baffle assembly is provided at the bottom of the light-shielding central tube. The baffle assembly has a gap for exposing the mouse tail. A hollow ventilation plug is provided inside the light-shielding central tube. The ventilation plug and the partition are movably connected along the axial direction of the light-shielding central tube. An observation lamp is detachably provided on the outer wall of the light-shielding central tube.

[0006] The principles and advantages of this scheme are: 1. The use of a light-proof central tube to contain mice provides a relatively dark environment, reducing stress responses caused by light stimulation. At the same time, multiple ventilated pores and hollow vent plugs reduce stress responses or anxiety caused by suffocation, preventing discomfort or death due to hypoxia. This makes the mice calmer during injection, reduces the possibility of struggling, and improves the operability of the injection.

[0007] 2. The vent plug can move along the axis of the light-proof central tube, thereby matching mice of different sizes, improving the versatility and adaptability of the device, and the hollow vent plug facilitates ventilation for the mice.

[0008] 3. The light-shielding central tube and the support can be rotated. Firstly, it is convenient to rotate the light-shielding central tube to a suitable angle to place the mouse inward. Secondly, after the mouse is placed, the operator can adjust it to a suitable angle according to their own habits to inject into the mouse's tail vein.

[0009] 4. The baffle assembly is easy to open and close, allowing mice to be placed into or removed from the light-proof central tube. The strip-shaped gap of the baffle assembly can expose the mouse tail, and when the first baffle and the second baffle are closed, the mouse tail naturally leaks out from the gap without the need for deliberate alignment or manual pulling to fix the mouse tail, reducing operation steps and stimulation to the mouse.

[0010] Preferably, as an improvement, the vent plug includes a conical section and a cylindrical section, the cylindrical section and the conical section are connected at the smaller diameter end, and the conical section is provided with a plurality of vent holes.

[0011] Technical effect: The above-mentioned configuration is adopted in this solution. The breathable plug has a conical section to accommodate the mouse's head. The conical structure can better match the shape of the mouse's head, so that the conical section fits the mouse's head, thereby restricting the movement of the mouse's head to a greater extent. In addition, the conical section allows the mouse's mouth to be close to the cylindrical section, which facilitates the mouse's breathing.

[0012] Preferably, as an improvement, the cylindrical segment is further provided with an annular protrusion, the protrusion being located at the end of the cylindrical segment away from the conical segment.

[0013] Technical effect: The above-mentioned configuration in this solution uses an annular protrusion as a physical limiter, which can effectively prevent the vent plug from being completely screwed into the light-shielding central tube and difficult to remove, ensuring the reliability and service life of the device. The protrusion also provides a force point, making it easy for the operator to apply force to rotate and adjust the vent plug.

[0014] Preferably, as an improvement, the cylindrical segment is provided with external threads, and the partition is provided with a partition threaded hole that mates with and connects to the cylindrical segment.

[0015] Technical effect: This solution adopts the above settings and uses a threaded connection. The operator can precisely and continuously adjust the position of the vent plug in the light-proof central tube by rotating it. The thread also has self-locking properties. After the vent plug is adjusted to the correct position, it can automatically maintain its position and is not easy to loosen due to the mouse struggling, thus ensuring the stability of the restraint effect.

[0016] Preferably, as an improvement, the baffle assembly includes a first baffle and a second baffle arranged symmetrically. Both the first baffle and the second baffle are hollow 1 / 4 spherical structures. The first baffle and the second baffle are rotatably connected to the two sides of the end of the light-shielding central tube by hinges, and the gap is located between the first baffle and the second baffle.

[0017] Technical effect: The above-mentioned configuration of this solution creates a hemispherical cavity when the first and second baffles are closed, which can fit the mouse's buttocks well, reduce the mouse's discomfort, and reduce the space for movement. In addition, during the closing process of the first and second baffles, the mouse's tail will move towards the center, so that when the baffles are fully closed, the mouse's tail will naturally emerge from the gap without the need for deliberate alignment or manual pulling to fix the mouse's tail, thus reducing operation steps and stimulation to the mouse.

[0018] Preferably, as an improvement, the first baffle is provided with a buckle, and the second baffle is provided with a slot that engages with the buckle.

[0019] Technical effect: The above-mentioned configuration of this solution, with the buckle and the slot cooperating to form a mechanical lock, can ensure that the first baffle and the second baffle remain closed during use, preventing the first baffle and the second baffle from rotating outward during use, which could cause the mouse to fall out of the light-proof central tube or be injured.

[0020] Preferably, as an improvement, the top of the bracket is provided with a rotating groove, and the outer wall of the light-shielding central tube is provided with a rotating shaft that is rotatably connected to the rotating groove.

[0021] Technical effect: The above-mentioned setup allows the light-shielding central tube to rotate relative to the support through the cooperation of the rotating shaft and the rotating groove. This enables the angle between the light-shielding central tube and the horizontal plane to be adjusted, allowing operators to flexibly adjust the mouse's position according to different injection needs and operating habits, thus providing more convenient conditions for injection operations.

[0022] Preferably, as an improvement, the bracket is further provided with a fixing groove, which is perpendicular to the rotating groove. A fixing bolt is threaded into the fixing groove, and the bolt head of the fixing bolt is provided with a lug.

[0023] Technical effect: The above-mentioned setup in this solution allows the fixing bolts to be tightened directly against the rotating shaft through the thread, providing a strong mechanical locking force, thereby restricting the rotation of the rotating shaft and fixing the light-shielding central tube at a preset angle, which will not change due to external force or the struggle of mice; at the same time, the design of the support ears increases the contact area between the operator and the bolt head, making it easier to tighten the fixing bolts.

[0024] Preferably, as an improvement, the observation lamp is provided with a support arm, the end of the support arm is provided with a card, and the light-shielding central tube is provided with a snap-fit ​​component that cooperates with the card.

[0025] Technical benefits: With the above-mentioned setup, the support arm can be twisted freely and provides support, allowing the operator to precisely position the light from the observation lamp to any part of the rat's tail and maintain a stable position; the combination of the card and the connector enables quick and secure installation and removal of the observation lamp, facilitating cleaning and bulb replacement.

[0026] Preferably, as an improvement, the base is provided with multiple suction cups at its bottom.

[0027] Technical benefits: The above-mentioned setup allows the entire device to be firmly attached to a smooth operating surface, preventing it from sliding or shaking during injection and providing a stable foundation for precise injection. Attached Figure Description

[0028] Figure 1 This is a structural schematic diagram of an embodiment of the present utility model.

[0029] Figure 2 This is a front view of an embodiment of the present utility model.

[0030] Figure 3 This is a cross-sectional view of an embodiment of the present utility model.

[0031] Figure 4 for Figure 3 Enlarged view of point A in the middle.

[0032] Figure 5 This is a schematic diagram of the card slot and buckle fit of this utility model.

[0033] Figure 6 This is a schematic diagram of the snap-fit ​​component structure of this utility model.

[0034] The reference numerals in the accompanying drawings include: light-shielding center tube 1, silicone pad 11, partition 12, partition vent hole 121, partition threaded hole 122, rotating shaft 13, base 2, suction cup 21, bracket 22, rotating groove 221, fixing groove 222, fixing bolt 3, support lug 31, vent plug 4, conical section 41, vent plug vent hole 411, cylindrical section 42, protrusion 421, baffle assembly 5, first baffle 51, buckle 511, second baffle 52, slot 521, hinge 6, snap-fit ​​7, observation lamp 8, support arm 81, and card 82. Detailed Implementation

[0035] The following detailed description illustrates the specific implementation method: Example The basics are as follows: Figure 1-6 As shown: A mouse tail vein injection restraint device, such as Figure 1 As shown, the device includes a base 2 and a light-shielding central tube 1. The light-shielding central tube 1 is used to hold the mouse. The bottom of the base 2 has multiple suction cups 21 for fixing the entire device to the operating table. Two supports 22 are symmetrically arranged on the base 2. The two sides of the light-shielding central tube 1 are rotatably connected to the supports 22. A horizontal rotating groove 221 is opened at the top of the supports 22. A rotating shaft 13 is provided on the outer wall of the light-shielding central tube 1, which is rotatably connected to the rotating groove 221. The cooperation between the rotating shaft 13 and the rotating groove 221 allows the light-shielding central tube 1 to rotate relative to the supports 22, adjusting the angle of the light-shielding central tube 1 with the horizontal plane. Simultaneously, to fix the light-shielding central tube 1 after adjusting its angle, as shown... Figure 4 As shown, the bracket 22 is also provided with a fixing groove 222, which is perpendicular to and communicates with the rotating groove 221. A fixing bolt 3 is threaded into the fixing groove 222. The fixing bolt 3 rotates and moves downward, so that the bottom of the fixing bolt 3 abuts against the rotating shaft 13, which can limit the rotation of the rotating shaft 13. Furthermore, the bolt head of the fixing bolt 3 is provided with a lug 31 to increase the contact area between the operator and the bolt head, making it easier to tighten the bolt.

[0036] The inner wall of the light-shielding central tube 1 is provided with a silicone pad 11. Both ends of the light-shielding central tube 1 have openings. A partition 12 is fixedly installed at the top opening of the light-shielding central tube 1, and the partition 12 has several ventilation holes 121 for the mouse to breathe. A baffle assembly 5 is provided at the bottom opening of the light-shielding central tube 1, such as... Figure 2As shown, the baffle assembly 5 includes a first baffle 51 and a second baffle 52 arranged symmetrically. Both the first baffle 51 and the second baffle 52 are hollow 1 / 4 spherical structures. The tops of the first baffle 51 and the second baffle 52 are rotatably connected to the bottom sides of the light-shielding central tube 1 via hinges 6. After the first baffle 51 and the second baffle 52 are closed in the middle, there is a vertical gap in the middle, which is used to expose the mouse tail.

[0037] Furthermore, in order to fix the first baffle 51 and the second baffle 52, such as... Figure 5 As shown, the first baffle 51 is provided with a buckle 511, and the second baffle 52 is provided with a slot 521 that engages with the buckle 511. When the first baffle 51 and the second baffle 52 are closed together, the buckle 511 engages with the slot 521, connecting the first baffle 51 and the second baffle 52 and preventing them from rotating outwards during use, which could cause the mouse to fall out of the light-proof central tube 1. The buckle 511 is provided with a protruding flap, which allows the operator to use the flap to disengage the buckle 511 from the slot 521 after injection. At this time, the first baffle 51 and the second baffle 52 rotate outwards simultaneously, making it easy to remove the mouse from the light-proof central tube 1.

[0038] A hollow vent plug 4 is provided inside the light-shielding central tube 1, and the vent plug 4 is movably connected to the partition layer 12 along the axial direction of the light-shielding central tube 1. Figure 3 As shown, the vent plug 4 includes a lower conical section 41 and an upper cylindrical section 42. The cylindrical section 42 is connected to the smaller diameter end of the conical section 41. The conical section 41 has several vent holes 411. The conical section 41 can accommodate the mouse's head and bring the mouse's mouth close to the cylindrical section 42, facilitating the mouse's ventilation. The cylindrical section 42 has external threads, and the partition 12 has a partition threaded hole 122 that mates with the cylindrical section 42, so that the cylindrical section 42 of the vent plug 4 is threadedly connected to the partition 12. Rotating the vent plug 4 can move the vent plug 4 inside or outside the light-shielding central tube 1 to fit mice of different sizes.

[0039] The cylindrical section 42 is also provided with an annular protrusion 421. The protrusion 421 is located at the end of the cylindrical section 42 away from the conical section 41, which limits the maximum displacement of the vent plug 4 and prevents the cylindrical section 42 from rotating completely into the light-shielding central tube 1 and becoming difficult to remove.

[0040] like Figure 1 As shown, an observation lamp 8 is detachably mounted on the outer wall of the light-shielding central tube 1. The observation lamp 8 includes a lampshade and a light source. The lampshade blocks the light beam, ensuring that the light only shines from a single angle, preventing light from other angles from interfering with the operator's vision. The observation lamp 8 has a support arm 81, which is a freely twistable and supportive structure. A clip 82 is located at the end of the support arm 81, and a snap-fit ​​connector 7 is provided on the light-shielding central tube 1 to engage with the clip 82. Figure 6 As shown, the snap-fit ​​component 7 consists of multiple snap-fit ​​strips. The snap-fit ​​strips on the left, right, and bottom sides are all L-shaped to prevent the card 82 from falling off. The snap-fit ​​strip on the top side is a strip-shaped structure to facilitate the insertion of the card 82.

[0041] In practical use, firstly, rotate the first baffle 51 and the second baffle 52 outwards simultaneously to expose the opening at the end of the light-shielding central tube 1. Place the mouse head-inward into the light-shielding central tube 1, then rotate the first baffle 51 and the second baffle 52 together in the middle. At this point, the buckle 511 and the slot 521 are engaged, restricting the rotation of the first baffle 51 and the second baffle 52. The mouse tail naturally leaks out from the gap between the first baffle 51 and the second baffle 52. Then, rotate the vent plug 4 closer to the mouse's head to reduce the mouse's movement space, thereby restricting the mouse's movement. Next, rotate the light-shielding central tube 1 to a suitable angle and tighten the fixing bolt 3 to restrict the rotation of the rotating shaft 13, so that the light-shielding central tube 1 can be fixed at the preset angle. Finally, adjust the support arm 81 so that the light emitted by the observation lamp 8 is aimed at the mouse's tail, making it easier to see the mouse's tail vein, and then the injection can be performed.

[0042] When the injection is complete and the mouse needs to be removed, flip the lever on the latch 511 to disengage the latch 511 from the slot 521, and rotate the first baffle 51 and the second baffle 52 outwards at the same time to remove the mouse.

[0043] The above descriptions are merely embodiments of this utility model. Commonly known technical solutions and / or characteristics are not described in detail here. It should be noted that those skilled in the art can make various modifications and improvements without departing from the technical solution of this utility model. These modifications and improvements should also be considered within the scope of protection of this utility model, and will not affect the effectiveness of the implementation of this utility model or the practicality of the patent. The scope of protection claimed in this application should be determined by the content of its claims, and the specific embodiments described in the specification can be used to interpret the content of the claims.

Claims

1. A mouse tail vein injection restraint device, characterized in that: The device includes a base and a light-shielding central tube. Two supports are symmetrically arranged on the base. The two sides of the light-shielding central tube are rotatably connected to the supports. A silicone pad is provided on the inner wall of the light-shielding central tube. Openings are provided at both ends of the light-shielding central tube. A partition is fixedly provided at the top of the light-shielding central tube. The partition has several ventilation holes. A baffle assembly is provided at the bottom of the light-shielding central tube. The baffle assembly has a gap for exposing the mouse tail. A hollow ventilation plug is provided inside the light-shielding central tube. The ventilation plug and the partition are movably connected along the axial direction of the light-shielding central tube. An observation lamp is detachably provided on the outer wall of the light-shielding central tube.

2. The mouse tail vein injection restraint device of claim 1, wherein: The vent plug includes a conical section and a cylindrical section, and the cylindrical section and the conical section are connected at the smaller diameter end. The conical section is provided with a plurality of vent holes.

3. The mouse tail vein injection restraint device of claim 2, wherein: The cylindrical section is also provided with an annular protrusion, which is located at the end of the cylindrical section away from the conical section.

4. The mouse tail vein injection restraint device of claim 3, wherein: The cylindrical section is provided with external threads, and the partition is provided with a partition threaded hole that mates with and connects to the cylindrical section.

5. The tail-vein injection restraint device for mice according to claim 1, wherein: The baffle assembly includes a first baffle and a second baffle arranged symmetrically. Both the first baffle and the second baffle are hollow 1 / 4 spherical structures. The first baffle and the second baffle are rotatably connected to the two sides of the end of the light-shielding central tube by hinges, and the gap is located between the first baffle and the second baffle.

6. The tail-vein injection restraint device for mice according to claim 5, wherein: The first baffle is provided with a buckle, and the second baffle is provided with a slot that engages with the buckle.

7. The tail-vein injection restraint device for mice according to claim 1, wherein: The top of the bracket is provided with a rotating groove, and the outer wall of the light-shielding central tube is provided with a rotating shaft that is rotatably connected to the rotating groove.

8. The mouse tail vein injection restraint device of claim 7, wherein: The bracket is also provided with a fixing groove, which is perpendicular to the rotating groove. A fixing bolt is threaded into the fixing groove, and the bolt head of the fixing bolt is provided with a lug.

9. The tail-vein injection restraint device for mice according to claim 1, wherein: The observation lamp is equipped with a support arm, and the end of the support arm is equipped with a card. The light-shielding central tube is equipped with a snap-fit ​​component that cooperates with the card.

10. The tail-vein injection restraint device for mice according to claim 1, wherein: The base has multiple suction cups at its bottom.

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