A universal sample magnetic bead rapid extraction kit

Abstract

This invention provides a universal sample magnetic bead rapid extraction kit, comprising: a box body, several placement mechanisms, several first adjustment mechanisms, several second adjustment mechanisms, and several reagent tubes; the box body has an internal cavity, and a cover is rotatably mounted on the box body, which movably closes the cavity; several first openings are opened on one side wall of the box body, and several second openings are opened on the other side wall, each first adjustment mechanism being movably located at one first opening, and each second adjustment mechanism being movably located at one second opening; several placement mechanisms are placed inside the cavity, each placement mechanism having one end connected to a first adjustment mechanism and the other end connected to a second adjustment mechanism; each reagent tube is placed on a placement mechanism. In use, through the coordinated installation of the box body, several placement mechanisms, several first adjustment mechanisms, and several second adjustment mechanisms, the corresponding reagent tube can be quickly retrieved as needed, which is simple, convenient, easy to operate, and saves time and effort.

Description

Technical Field

[0001] This utility model relates to the field of reagent kit technology, and in particular to a universal sample magnetic bead rapid extraction reagent kit. Background Technology

[0002] The magnetic bead-based nucleic acid extraction kit is a high-tech product combining bioscience and nanomaterials science, representing a major breakthrough in nucleic acid extraction and purification technology in my country. It completely solves the long-standing reliance on imports for nucleic acid extraction and purification in my country. Based on the same principle as silica membrane centrifuge columns, it uses nanotechnology to improve and modify the surface of superparamagnetic nanoparticles to prepare superparamagnetic silica nanobeads. However, currently, each kit contains a large number of reagent tubes, which need to be handled during use. The reagent tubes located in the middle are inconvenient to handle and require considerable effort. Therefore, there is an urgent need for a universal sample magnetic bead rapid extraction kit to solve this problem. Utility Model Content

[0003] To solve the above problems, the present invention adopts the following technical solution: a general sample magnetic bead rapid extraction kit, comprising: a box, several placement mechanisms, several first adjustment mechanisms, several second adjustment mechanisms, and several reagent tubes;

[0004] The box has an internal cavity, and a cover is rotatably mounted on the box, which movably covers the cavity.

[0005] The box body has a plurality of first openings on one side wall and a plurality of second openings on the other side wall. Each first adjustment mechanism is movably located in a first opening and each second adjustment mechanism is movably located in a second opening.

[0006] A plurality of the placement mechanisms are placed in the cavity, with one end of each placement mechanism connected to a first adjustment mechanism and the other end connected to a second adjustment mechanism;

[0007] Each of the reagent tubes is placed on one of the placement mechanisms.

[0008] Furthermore, a plurality of the first openings are equally spaced, a plurality of the second openings are equally spaced, and each first opening corresponds to one second opening.

[0009] Furthermore, each of the placement mechanisms includes a limiting frame and a plurality of placement seats, the plurality of placement seats being arranged sequentially at intervals, the limiting frame being disposed on the outside of each of the placement seats, and each of the placement seats being used to place one of the reagent tubes.

[0010] Furthermore, each of the two sidewalls of the first opening is provided with a plurality of first protrusions, and the plurality of first protrusions are arranged at equal intervals.

[0011] Furthermore, each of the two sidewalls of the second opening is provided with a plurality of second protrusions, and the plurality of second protrusions are equidistantly arranged.

[0012] Furthermore, each of the limiting frames is provided with a first mounting block at one end and a second mounting block at the other end, with the first mounting block and the second mounting block being symmetrically arranged.

[0013] Furthermore, each of the first adjustment mechanisms includes a first mounting bracket, a first spring, a first pressure rod, two first limiting blocks, and two first return springs. A first limiting sleeve is provided on the first mounting bracket, the first pressure rod movably passes through the first limiting sleeve, a first pressure block is provided on the first pressure rod, one end of the first spring is provided on the first mounting bracket, and the other end abuts against the first pressure block. The two first limiting blocks are rotatably provided on the first mounting bracket, one end of each first return spring is provided on the first mounting bracket, and the other end is connected to one end of a first limiting block. A first push block is provided on the first pressure rod, and the first push block movably abuts against the two first limiting blocks.

[0014] Furthermore, each of the second adjustment mechanisms includes a second mounting bracket, a second spring, a second pressure rod, two second limiting blocks, and two second return springs. A second limiting sleeve is provided on the second mounting bracket, the second pressure rod moves through the second limiting sleeve, a second pressure block is provided on the second pressure rod, one end of the second spring is provided on the second mounting bracket, and the other end abuts against the second pressure block. The two second limiting blocks are rotatably provided on the second mounting bracket, one end of each second return spring is provided on the second mounting bracket, and the other end is connected to one end of a second limiting block. A second push block is provided on the second pressure rod, and the second push block moves against the two second limiting blocks.

[0015] Furthermore, each of the reagent tubes is provided with a flip-top, which covers the opening of the reagent tube.

[0016] Furthermore, each of the flip covers is provided with a top block, and each of the flip covers is provided with a recessed opening, with the top block and the recessed opening spaced apart.

[0017] The beneficial effects of this utility model are as follows: By using this universal sample magnetic bead rapid extraction kit, through the coordinated installation of the box, several placement mechanisms, several first adjustment mechanisms and several second adjustment mechanisms, the corresponding reagent tubes can be quickly retrieved according to the needs. It is simple, convenient, easy to operate, and saves time and effort. Attached Figure Description

[0018] The accompanying drawings further illustrate the present invention, but the embodiments in the drawings do not constitute any limitation on the present invention.

[0019] Figure 1 A schematic diagram of one orientation of a general-purpose sample magnetic bead rapid extraction kit provided in one embodiment;

[0020] Figure 2 Another schematic diagram of a general-purpose sample magnetic bead rapid extraction kit provided in one embodiment;

[0021] Figure 3 A schematic diagram of a placement mechanism provided in one embodiment;

[0022] Figure 4 This is a schematic diagram of the first adjustment mechanism installed in one direction according to one embodiment;

[0023] Figure 5 This is a schematic diagram of the second adjustment mechanism installed in one direction according to one embodiment. Detailed Implementation

[0024] The technical solution of this utility model will be further described below with reference to the accompanying drawings of the embodiments. This utility model is not limited to the following specific embodiments. It should be noted that, unless otherwise specified, the embodiments and features in the embodiments of this utility model can be combined with each other.

[0025] like Figure 1 As shown, a general-purpose sample magnetic bead rapid extraction kit includes: a box body 100, several placement mechanisms, several first adjustment mechanisms, several second adjustment mechanisms, and several reagent tubes; the box body 100 has an internal cavity, and a cover 500 is rotatably disposed on the box body 100, the cover 500 movably covering the cavity; several first openings 110 are opened on one side wall of the box body 100, and several second openings 120 are opened on the other side wall, each first adjustment mechanism is movably located in a first opening 110, and each second adjustment mechanism is movably located in a second opening 120; several placement mechanisms are placed in the cavity, one end of each placement mechanism is connected to a first adjustment mechanism, and the other end is connected to a second adjustment mechanism; each reagent tube is placed on a placement mechanism.

[0026] Specifically, a plurality of first openings 110 are equidistantly spaced, and a plurality of second openings 120 are equidistantly spaced, with each first opening 110 corresponding to one second opening 120. Each placement mechanism includes a limiting frame 210 and a plurality of placement seats 220, which are arranged sequentially at intervals. The limiting frame 210 is located on the outer side of each placement seat 220, and each placement seat 220 is used to place one reagent tube. A plurality of first protrusions 111 are respectively provided on the two side walls of each first opening 110, and the plurality of first protrusions 111 are equidistantly spaced. A plurality of second protrusions 121 are respectively provided on the two side walls of each second opening 120, and the plurality of second protrusions 121 are equidistantly spaced.

[0027] In the above embodiments, each of the limiting frames 210 is provided with a first mounting block 211 at one end and a second mounting block 221 at the other end, and the first mounting block 211 and the second mounting block 221 are symmetrically arranged. Each of the first adjustment mechanisms includes a first mounting bracket 310, a first spring 320, a first pressure rod 330, two first limiting blocks 340, and two first return springs 350. A first limiting sleeve 311 is provided on the first mounting bracket 310, and the first pressure rod 330 moves through the first limiting sleeve 311. A first pressure block 331 is provided on the first pressure rod 330. One end of the first spring 320 is provided on the first mounting bracket 310, and the other end abuts against the first pressure block 331. The two first limiting blocks 340 are rotatably provided on the first mounting bracket 310. One end of each of the first return springs 350 is provided on the first mounting bracket 310, and the other end is connected to one end of a first limiting block 340. A first push block 332 is provided on the first pressure rod 330, and the first push block 332 moves against the two first limiting blocks 340. Each of the second adjustment mechanisms includes a second mounting bracket 410, a second spring 420, a second pressure rod 430, two second limiting blocks 440, and two second return springs 450. A second limiting sleeve 411 is provided on the second mounting bracket 410. The second pressure rod 430 movably passes through the second limiting sleeve 411. A second pressure block 431 is provided on the second pressure rod 430. One end of the second spring 420 is provided on the second mounting bracket 410, and the other end abuts against the second pressure block 431. The two second limiting blocks 440 are rotatably mounted on the second mounting bracket 410. One end of each second return spring 450 is provided on the second mounting bracket 410, and the other end is connected to one end of a second limiting block 440. A second push block 432 is provided on the second pressure rod 430, and the second push block 432 movably abuts against the two second limiting blocks 440. In other words, the first mounting bracket 310 is mounted on the first mounting block 211, and the second mounting bracket 410 is mounted on the second mounting block 221. Each first mounting block 211 has a first through hole, and each first pressure rod 330 partially moves through the first through hole. Each second mounting block 221 has a second through hole, and each second pressure rod 430 partially passes through the second through hole.

[0028] Each first limiting block 340 is movably located on a first protrusion 111 and is supported by the first protrusion 111. Each second limiting block 440 is movably located on a second protrusion 121 and is supported by the second protrusion 121.

[0029] In one embodiment, each reagent tube is provided with a flip-top, which covers the opening of the reagent tube. Each flip-top is provided with a top block and a recessed opening, with the top block and the recessed opening spaced apart.

[0030] In the initial state, all placement mechanisms of this universal sample magnetic bead rapid extraction kit are located at the lowest point within the cavity, meaning that each of the first and second adjustment mechanisms is in contact with the bottom of the inner wall of the cavity. This allows the lid 500 on the housing 100 to close, ensuring all reagent tubes are placed within the cavity.

[0031] In use, staff can open the cover 500 according to the position of the reagent tube to be retrieved, and align it with the placement limit frame 210. By pressing the first pressure rod 330 and the second pressure rod 430 on the limit frame 210, the first pressure rod 330 and the second pressure rod 430 are moved into the cavity. Since the first mounting frame 310 is provided with the first limit sleeve 311, the first pressure rod 330 will not shift during the pressing process. Similarly, the second mounting frame 410 is provided with the second limit sleeve 411, so the second pressure rod 430 will not shift left or right during the pressing process. In other words, when the first pressure rod 330 is pressed and moves inward, the first push block 332 abuts against and continuously pushes the two first limit blocks 340, causing the other end of each first limit block 340 to move closer to the first pressure rod 330. This results in the two first limit blocks 340 retracting towards the first pressure rod 330. Similarly, the two second limit blocks 440 also retract towards the second pressure rod 430. Finally, neither of the two first limit blocks 340 abuts against the lowest first protrusion 111, and neither of the two second limit blocks 440 abuts against the lowest second protrusion 121. In other words, after retraction, the operator can directly maintain the pressing state and push the first pressure rod 330 and the second pressure rod 430 upward, which will drive the limit frame 210 to move upward. It is worth mentioning that when pressed, the first pressing block 331 presses the first spring 320, causing the first spring 320 to be in a contracted state. At the same time, the two first limiting blocks 340, pushed by the first pushing block 332, also compress the first return spring 350 at one end, causing both first return springs 350 to be in a contracted state. Similarly, the second pressing block 431 presses the second spring 420, causing the second spring 420 to be in a contracted state. At the same time, the two second limiting blocks 440, pushed by the second pushing block 432, also compress the second return spring 450 at one end, causing both second return springs 450 to be in a contracted state. When moved to the appropriate position, slowly release the pressure on the first pressure rod 330 and the second pressure rod 430. At this time, due to the elastic force of the first spring 320, the first pressure rod 330 is pushed outward, that is, the first push block 332 slowly stops abutting against the two first limiting blocks 340. Therefore, under the action of the elastic force, one end of the first limiting block 340 connected to the first return spring 350 moves towards the first pressure rod 330, which causes the other end to move away from the first pressure rod 330, and then abut against the first protrusion 111 at the corresponding height. Similarly, the reset of the second pressure rod 430 and the two second limiting blocks 440 is the same as the reset of the first pressure rod 330 and the two first limiting blocks 340, so it will not be described in detail.In other words, after moving to the corresponding height, the two first protrusions 111 at the corresponding height support the two first limiting blocks 340, and the two second protrusions 121 support the two second limiting blocks 440. Therefore, the entire limiting frame 210 can be supported and fixed at the required height. At this time, since the adjacent limiting frames 210 are not at the same height, it is very convenient to take any reagent tube on this limiting frame 210. It is worth mentioning that, because several first protrusions 111 and several second protrusions 121 are provided, all the limiting frames 210 can be adjusted to be at different heights, thus making it easy to take any reagent tube located on the placement seat 220.

[0032] Furthermore, after taking out the test tube, staff only need to place their finger in the recessed opening, and then push the top block upwards with their fingernail to open and use it, which is simple and convenient.

[0033] In summary, the above embodiments are not limiting embodiments of this utility model. Any modifications or equivalent variations made by those skilled in the art based on the substantive content of this utility model are within the technical scope of this utility model.

Claims

1. A universal sample magnetic bead rapid extraction kit, characterized in that, include: The box body, several placement mechanisms, several first adjustment mechanisms, several second adjustment mechanisms, and several reagent tubes; The box has an internal cavity, and a cover is rotatably mounted on the box, which movably covers the cavity. The box body has a plurality of first openings on one side wall and a plurality of second openings on the other side wall. Each first adjustment mechanism is movably located in a first opening and each second adjustment mechanism is movably located in a second opening. A plurality of the placement mechanisms are placed in the cavity, with one end of each placement mechanism connected to a first adjustment mechanism and the other end connected to a second adjustment mechanism; Each of the reagent tubes is placed on one of the placement mechanisms.

2. The universal sample magnetic bead rapid extraction kit according to claim 1, characterized in that: A plurality of first openings are equally spaced, and a plurality of second openings are equally spaced, with each first opening corresponding to one second opening.

3. The universal sample magnetic bead rapid extraction kit according to claim 2, characterized in that: Each of the placement mechanisms includes a limiting frame and a plurality of placement seats, the plurality of placement seats being arranged sequentially at intervals, the limiting frame being disposed on the outside of each of the placement seats, and each of the placement seats being used to place one of the reagent tubes.

4. The universal sample magnetic bead rapid extraction kit according to claim 3, characterized in that: Each of the first openings has a plurality of first protrusions on its two sidewalls, and the plurality of first protrusions are equidistant from each other.

5. The universal sample magnetic bead rapid extraction kit according to claim 4, characterized in that: Each of the two sidewalls of the second opening is provided with a plurality of second protrusions, and the plurality of second protrusions are equidistantly arranged.

6. The universal sample magnetic bead rapid extraction kit according to claim 5, characterized in that: Each of the limiting frames has a first mounting block at one end and a second mounting block at the other end, with the first mounting block and the second mounting block being symmetrically arranged.

7. The universal sample magnetic bead rapid extraction kit according to claim 6, characterized in that: Each of the first adjustment mechanisms includes a first mounting bracket, a first spring, a first pressure rod, two first limiting blocks, and two first return springs. A first limiting sleeve is provided on the first mounting bracket, the first pressure rod moves through the first limiting sleeve, a first pressure block is provided on the first pressure rod, one end of the first spring is provided on the first mounting bracket, and the other end abuts against the first pressure block. The two first limiting blocks are rotatably provided on the first mounting bracket. One end of each of the first return springs is provided on the first mounting bracket, and the other end is connected to one end of a first limiting block. A first push block is provided on the first pressure rod, and the first push block moves against the two first limiting blocks.

8. The universal sample magnetic bead rapid extraction kit according to claim 7, characterized in that: Each of the second adjustment mechanisms includes a second mounting bracket, a second spring, a second pressure rod, two second limiting blocks, and two second return springs. A second limiting sleeve is provided on the second mounting bracket, and the second pressure rod movably passes through the second limiting sleeve. A second pressure block is provided on the second pressure rod. One end of the second spring is provided on the second mounting bracket, and the other end abuts against the second pressure block. The two second limiting blocks are rotatably provided on the second mounting bracket. One end of each of the second return springs is provided on the second mounting bracket, and the other end is connected to one end of a second limiting block. A second push block is provided on the second pressure rod, and the second push block movably abuts against the two second limiting blocks.

9. The universal sample magnetic bead rapid extraction kit according to claim 8, characterized in that: Each of the reagent tubes is provided with a flip-top, which covers the opening of the reagent tube.

10. The universal sample magnetic bead rapid extraction kit according to claim 9, characterized in that: Each of the flip covers is provided with a top block, and each of the flip covers is provided with a recessed opening, and the top block is arranged in a spaced manner with the recessed opening.

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