A erythrocyte sedimentation rate (ESR) mixer

CN224636285UActive Publication Date: 2026-08-14BEIJING CHUIYANGLIU HOSPITAL
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-07-04
Publication Date
2026-08-14

AI Technical Summary

Technical Problem

[0004]本实用新型要解决的技术问题是提供一种血沉混匀器,通过设置夹持组件,不仅可以快速实现对试管的夹持与固定,而且可以适应不同型号的试管,夹持组件内结构之间在功能上环环相扣,相辅相成,既能保证抗凝剂与血液充分融合,又不损伤红细胞,确保血沉检测结果真实反映病理状态,通过以上的设置可以解决现有的混匀设备无法精准匹配血沉检测对样本混匀的温和性和均匀性需求的问题

Benefits of technology

[0019] In the above solution, by setting up a clamping component, not only can the test tube be quickly clamped and fixed, but it can also adapt to different sizes of test tubes. The internal structures of the clamping component are interlocked and complementary in function. The overall structure is made of elastic silicone material, which can adapt to different sizes of test tubes and avoid damage to the test tubes when clamping. It can ensure that the anticoagulant and blood are fully mixed without damaging the red blood cells, and ensure that the erythrocyte sedimentation rate test results truly reflect the pathological state.

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Abstract

This invention provides an erythrocyte sedimentation rate (ESR) mixer, belonging to the field of medical device technology. It includes a body with a mixing platform rotatably connected inside, and a pair of rotating shafts rotatably connected to the mixing platform; a clamping assembly for clamping test tubes for ESR testing, connected to the rotating shafts; the clamping assembly includes a hub fixedly connected to the rotating shafts, symmetrically distributed adjusting rods fixedly connected to the outer wall of the hub, clamping plates arranged in a circular pattern fixedly connected to the free ends of the adjusting rods, and a limiting rod fixedly connected to the outer wall of the hub, with a positioning sleeve fixedly connected to the free end of the limiting rod; the adjusting rods, clamping plates, limiting rods, and positioning sleeves are all made of elastic silicone. By setting up the clamping assembly, test tubes of different sizes can be quickly clamped. The use of elastic silicone in the clamping assembly ensures that the anticoagulant fully mixes with the blood without damaging red blood cells, ensuring that the ESR test results accurately reflect the pathological state.
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Description

Technical Field

[0001] This utility model relates to the field of medical device technology, and in particular to a blood sedimentation rate mixer. Background Technology

[0002] Erythrocyte sedimentation rate (ESR) mixers are used to solve the problem of uniform mixing of blood samples before testing. Traditional ESR testing relies on manual operation (such as manually shaking the test tube), and the mixing force and time are difficult to standardize, resulting in poor sample uniformity and affecting the accuracy of test results. Moreover, manual operation is inefficient, especially when processing batches of samples, which is time-consuming and labor-intensive, and there is a risk of sample splashing and cross-contamination.

[0003] Existing automated mixing equipment is mostly general-purpose (such as vortex mixers), lacking customized design for erythrocyte sedimentation rate (ESR) test samples (test tube size, mixing parameters). Since ESR testing requires the natural sedimentation of red blood cells, vigorous mixing can damage the red blood cell structure or cause hemolysis, affecting the accuracy of the sedimentation rate. Inhomogeneous mixing can lead to local aggregation of coagulation factors, interfering with the sedimentation process. Therefore, during ESR testing, the blood sample must be mixed neither too vigorously nor too evenly. Existing mixing equipment cannot accurately match the requirements of ESR testing for both gentle and uniform sample mixing. Therefore, this invention provides an ESR mixer to meet these requirements. Utility Model Content

[0004] The technical problem this invention aims to solve is to provide an erythrocyte sedimentation rate (ESR) mixer. By setting up a clamping component, it can not only quickly clamp and fix test tubes, but also adapt to test tubes of different sizes. The internal structures of the clamping component are interlocked and complementary in function, which can ensure that the anticoagulant and blood are fully mixed without damaging red blood cells, and ensure that the ESR test results truly reflect the pathological state. Through the above settings, the problem that existing mixing equipment cannot accurately match the mildness and uniformity requirements of ESR testing for sample mixing can be solved.

[0005] To solve the above-mentioned technical problems, this utility model provides the following technical solution:

[0006] A erythrocyte sedimentation rate (ESR) mixer includes a body, a mixing platform rotatably connected inside the body, and a pair of rotating shafts rotatably connected to the mixing platform; and a clamping assembly for clamping test tubes for ESR testing, the clamping assembly being connected to the rotating shafts.

[0007] The clamping assembly includes a hub fixedly connected to the rotating shaft, symmetrically distributed adjusting rods fixedly connected to the outer wall of the hub, clamping plates arranged in a circular pattern fixedly connected to the free end of the adjusting rods, and a limiting rod fixedly connected to the outer wall of the hub, with a positioning sleeve fixedly connected to the free end of the limiting rod.

[0008] The adjusting rod, the clamping plate, the limiting rod, and the positioning sleeve are all made of elastic silicone.

[0009] Optionally, the mixing platform includes a bottom disk and vertical plates fixed to both sides of the disk, with two rotating shafts installed parallel between the two vertical plates.

[0010] Optionally, the clamping assembly includes a hub fixedly connected to the rotating shaft, with symmetrically distributed adjusting rods fixedly connected to the outer wall of the hub, and clamping plates arranged in a circular pattern fixedly connected to the free end of the adjusting rods. A limiting rod is also fixedly connected to the outer wall of the hub, and a positioning sleeve is fixedly connected to the free end of the limiting rod.

[0011] Optionally, the hubs on the outer walls of the pair of rotating shafts are staggered, and the hubs are evenly distributed on the outer walls of the rotating shafts.

[0012] Optionally, the adjusting rod is a curved elastic structure with a circular cross-section, and the bent part of the adjusting rod is provided with uniformly distributed lightweight grooves.

[0013] Optionally, the clamping piece is a curved elastic structure, the cross-section of the clamping piece is an S-shaped structure, and the free end of the clamping piece has an outward tilting angle.

[0014] Optionally, the limiting rod is a curved elastic structure with a circular cross-section, and the bending part of the limiting rod is provided with uniformly distributed weakening grooves.

[0015] Optionally, the position of the limiting rod corresponds to the center between the adjusting rods, and both ends of the positioning sleeve have an outward tilting angle.

[0016] Optionally, the adjusting rod and the clamping piece are manufactured as a single piece, and the limiting rod and the positioning sleeve are manufactured as a single piece.

[0017] Optionally, a servo motor is provided on one side of the mixing platform, and the output shaft of the servo motor is fixedly connected to the rotation shaft.

[0018] Compared with the prior art, this utility model has at least the following beneficial effects:

[0019] In the above solution, by setting up a clamping component, not only can the test tube be quickly clamped and fixed, but it can also adapt to different sizes of test tubes. The internal structures of the clamping component are interlocked and complementary in function. The overall structure is made of elastic silicone material, which can adapt to different sizes of test tubes and avoid damage to the test tubes when clamping. It can ensure that the anticoagulant and blood are fully mixed without damaging the red blood cells, and ensure that the erythrocyte sedimentation rate test results truly reflect the pathological state.

[0020] By setting up a mixing platform and a rotating shaft, a combined motion of horizontal rotation and slight up-and-down vibration of the test tubes is achieved. While the mixing platform rotates horizontally, the test tubes on the rotating shaft swing along with the shaft. The solution sways and eddies due to inertia, simulating the left-right shaking motion of an artificial wrist. This ensures that the swing amplitude is stable, avoiding hemolysis caused by violent shaking, and promoting uniform mixing of the solution through regular reciprocating motion, thus meeting the experimental requirements for the gentleness and uniformity of sample processing.

[0021] By incorporating adjusting rods, clamping plates, limiting rods, and positioning sleeves, this system not only accommodates different types of test tubes and accommodates test tubes of varying thicknesses and lengths, but also provides multi-point clamping to ensure the stability of the test tubes during mixing. Both ends of the test tubes are clamped and enclosed, and the fully enclosed clamping design reduces the risk of sample exposure and operator contact, meeting the biosafety requirements for medical testing. Attached Figure Description

[0022] The accompanying drawings, which are incorporated herein and form part of the specification, illustrate embodiments of the present invention and, together with the specification, further serve to explain the principles of the present invention and enable those skilled in the art to implement and use the present invention.

[0023] Figure 1 A first-view three-dimensional structural diagram of an erythrocyte sedimentation rate (ESR) mixer.

[0024] Figure 2 A schematic diagram of the second-view three-dimensional structure of the erythrocyte sedimentation rate (ESR) mixer.

[0025] Figure 3 A schematic diagram of the third-person perspective structure of the erythrocyte sedimentation rate (ESR) homogenizer.

[0026] Figure 4 A schematic diagram of the fourth-angle three-dimensional structure of the erythrocyte sedimentation rate (ESR) mixer.

[0027] Figure 5 This is an enlarged three-dimensional structural diagram of the clamping component;

[0028] Figure 6 for Figure 3 Enlarged 3D structural diagram at point A.

[0029] Figure label:

[0030] 1. Body; 2. Mixing platform; 3. Rotating shaft; 4. Hub; 5. Adjusting rod; 6. Clamping plate; 7. Lightweighting groove; 8. Limiting rod; 9. Positioning sleeve; 10. Weakening groove.

[0031] As shown in the figure, specific structures and devices are marked in the figure to clearly illustrate the structure of the embodiment of this utility model. However, this is only for illustrative purposes and is not intended to limit this utility model to this specific structure, device and environment. Those skilled in the art can adjust or modify these devices and environments according to specific needs. Detailed Implementation

[0032] The erythrocyte sedimentation rate (ESR) mixer provided by this utility model will be described in detail below with reference to the accompanying drawings and specific embodiments. It should be noted that, to make the embodiments more detailed, the following embodiments are the best and preferred embodiments, and those skilled in the art can use other alternative methods to implement some known technologies; moreover, the accompanying drawings are only for more specific description of the embodiments and are not intended to specifically limit this utility model.

[0033] It should be noted that the use of terms such as "an embodiment," "an embodiment," "an exemplary embodiment," and "some embodiments" in the specification indicates that the described embodiment may include a specific feature, structure, or characteristic, but not every embodiment necessarily includes that specific feature, structure, or characteristic. Furthermore, when a specific feature, structure, or characteristic is described in connection with an embodiment, implementing such a feature, structure, or characteristic in conjunction with other embodiments (whether explicitly described or not) should be within the knowledge of those skilled in the art.

[0034] Generally, terms can be understood at least partly from their use in context. For example, depending at least partly on the context, the term "one or more" as used herein can be used to describe any feature, structure, or characteristic in a singular sense, or a combination of features, structures, or characteristics in a plural sense. Additionally, the term "based on" can be understood not necessarily to convey an exclusive set of factors, but rather, alternatively, depending at least partly on the context, to allow for the presence of other factors that are not necessarily explicitly described.

[0035] It is understood that the meanings of “on”, “above”, and “above” in this utility model should be interpreted in the broadest manner, such that “on” not only means “directly on” something, but also includes the meaning of being “on” something with an intervening feature or layer, and that “above” or “above” not only means “on” something, but also includes the meaning of being “on” something without an intervening feature or layer.

[0036] Furthermore, spatially related terms such as “below,” “under,” “lower,” “above,” and “upper” are used herein for convenience to describe the relationship of one element or feature to one or more other elements or features, as illustrated in the accompanying drawings. Spatially related terms are intended to cover different orientations in the use or operation of the device other than those depicted in the accompanying drawings. The device may be oriented in other ways, and the spatially related descriptive terms used herein can be interpreted similarly.

[0037] like Figures 1 to 6 As shown, an embodiment of this utility model provides an erythrocyte sedimentation rate (ESR) mixer, including a body 1, a mixing platform 2 rotatably connected inside the body 1, and a pair of rotating shafts 3 rotatably connected to the mixing platform 2; a clamping assembly for clamping test tubes for ESR testing, the clamping assembly being connected to the rotating shafts 3. The ESR mixer provided in this application mainly drives the sample to oscillate or rotate through a mechanical device, so as to set the frequency and amplitude to mix the blood with the anticoagulant, achieving uniform mixing while avoiding damage to red blood cells, and ensuring that the sample state is consistent before testing.

[0038] like Figures 1 to 6 As shown, the clamping assembly includes a hub 4 fixedly connected to the rotating shaft 3. A symmetrically distributed adjusting rod 5 is fixedly connected to the outer wall of the hub 4. A clamping piece 6 arranged in a circular pattern is fixedly connected to the free end of the adjusting rod 5. A limiting rod 8 is also fixedly connected to the outer wall of the hub 4. A positioning sleeve 9 is fixedly connected to the free end of the limiting rod 8. The adjusting rod 5, clamping piece 6, limiting rod 8 and positioning sleeve 9 are all made of elastic silicone.

[0039] By setting up a clamping component, not only can test tubes be quickly clamped and fixed, but it can also adapt to different sizes of test tubes. The internal structures of the clamping component are interlocked and complementary in function. The overall structure is made of elastic silicone material, which can adapt to different sizes of test tubes and avoid damage to the test tubes when clamping. It can ensure that the anticoagulant and blood are fully mixed without damaging red blood cells, and ensure that the erythrocyte sedimentation rate test results truly reflect the pathological state.

[0040] Hubs 4 are staggered on the outer walls of a pair of rotating shafts 3, and the hubs 4 are evenly distributed on the outer walls of the rotating shafts 3. This is used to avoid interference during rotation and to make full use of space.

[0041] Specifically, the machine body 1 is equipped with a drive motor, which is fixedly connected to the bottom of the mixing platform 2. Starting the drive motor can drive the mixing platform 2 to rotate horizontally, and the speed and time of the horizontal rotation of the mixing platform 2 can be adjusted as needed.

[0042] Furthermore, the mixing platform 2 includes a bottom disc and vertical plates fixed to both sides of the disc. Two rotating shafts 3 are installed parallel between the two vertical plates, and one side of each rotating shaft 3 is fixedly connected to a servo motor (e.g., Figures 1 to 3 As shown), the test tube is held between two clamping plates 6 and passes through the positioning sleeves 9, forming a three-point fixed test tube to maintain its stability in the mixing state. The servo motor precisely controls the speed and angular displacement, and the rotating shaft 3 rotates back and forth within a preset angle range, mixing the solution in the test tube. The hubs 4 on the two rotating shafts 3 are staggered (as shown). Figures 2 to 3 As shown in the figure, this ensures that the mixing process on both sides does not interfere with each other.

[0043] By setting up a mixing platform 2 and a rotating shaft 3 in combination, a combined motion of horizontal rotation and slight up-and-down vibration of the test tube is achieved. While the mixing platform 2 rotates horizontally, the test tube on the rotating shaft 3 swings with the shaft. The solution shakes and eddies due to inertia, simulating the left-right shaking motion of an artificial wrist. This ensures that the swing amplitude is stable, avoiding hemolysis caused by violent shaking, and promoting uniform mixing of the solution through regular reciprocating motion, thus meeting the experimental requirements for the mildness and uniformity of sample processing.

[0044] As one implementation method in this embodiment, such as Figures 1 to 6 As shown, the adjusting rod 5 is a curved elastic structure with a circular cross-section. Uniformly distributed lightweight grooves 7 are provided at the bend of the adjusting rod 5. The clamping plate 6 is a curved elastic structure with an S-shaped cross-section. The free end of the clamping plate 6 has an outward tilting angle (e.g., ...). Figure 5 As shown), it generates bidirectional elastic deformation when clamping test tubes to adapt to test tubes of different diameters. The adjusting rod 5 and the clamping plate 6 are manufactured as a single piece, and the limiting rod 8 is a curved elastic structure with a circular cross-section. The bending part of the limiting rod 8 is provided with uniformly distributed weakening grooves 10 (as shown). Figure 6 As shown), the position of the limiting rod 8 corresponds to the center between the adjusting rod 5 (as shown). Figure 5 As shown), both ends of the positioning sleeve 9 have an outward tilting angle (as shown). Figure 6 As shown, the limit rod 8 and the positioning sleeve 9 are manufactured as a single piece.

[0045] Furthermore, since both the adjusting rod 5 and the clamping piece 6 are made of elastic material, the angle of the adjusting rod 5 can be adjusted to accommodate test tubes of different lengths. The adjusting rod 5 also has evenly distributed lightweight grooves 7, facilitating easy adjustment and allowing for more elastic deformation at these grooves, thus adapting to test tubes of different lengths. The clamping pieces 6 are evenly distributed around the circumference, forming a clamping and placement cavity. The bottom of the test tube is inserted into the clamping piece 6. The elastic deformation of the clamping piece 6 not only accommodates test tubes of different thicknesses but also prevents slippage after clamping. Similarly, the other end of the test tube is placed in the clamping piece 6 on the other side, ensuring a secure placement. Then, the positioning sleeve 9 is clamped onto the outer wall of the test tube. The limiting rod 8 and the positioning sleeve 9 also have elastic properties, and the limiting rod 8 has an S-shaped movement (e.g., Figure 6 As shown, it can adapt to different distances between the test tube and the hub 4, satisfying the three-point clamping of the test tube. Furthermore, the adjusting rod 5, clamping plate 6, limiting rod 8, and positioning sleeve 9 are all made of elastic silicone, which can adapt to test tubes of different specifications, avoiding damage to the test tube during clamping. The elastic silicone material can withstand reciprocating deformation without plastic deformation.

[0046] By using the adjustment rod 5, clamping plate 6, limiting rod 8 and positioning sleeve 9, it can not only adapt to different models of test tubes and meet the needs of test tubes of different thicknesses and lengths, but also ensure the stability of the test tubes in the mixed state by multi-point clamping. Both ends of the test tubes are clamped and wrapped. The fully enclosed clamping design reduces the risk of sample exposure and operator contact, and meets the biosafety requirements of medical testing.

[0047] Specifically, the working principle of the erythrocyte sedimentation rate (ESR) homogenizer is disclosed as prior art and will not be elaborated further here. The machine body 1 has a built-in control system, which allows users to preset parameters such as mixing time, rotation speed, and tilt angle through a touch screen interface. It also supports custom program storage (such as adapting to standardized processes of different testing institutions). The specific structure and working principle of the control system and touch screen are disclosed as prior art and will not be elaborated further here. A servo motor is installed on one side of the mixing platform 2. The output shaft of the servo motor is fixedly connected to the central axis of the rotating shaft 3. The servo motor drives the rotation speed and tilt angle of the rotating shaft 3. The specific structure and working principle of the servo motor are disclosed as prior art and will not be elaborated further here.

[0048] This utility model also provides a mixing method for an erythrocyte sedimentation rate (ESR) mixer, comprising the following steps:

[0049] Step 1: Place the test tube containing the erythrocyte sedimentation rate (ESR) sample into the clamping assembly, and adjust the tilt angle of the test tube to the preset value (5°-15°) by adjusting the elastic deformation of the adjusting rod 5.

[0050] Step 2: Select the mixing mode (standard mode / custom mode) on the touch screen, and enter the rotation speed and time;

[0051] Step 3: Start the equipment. The drive motor and servo motor drive the mixing platform 2 and the rotating shaft 3 to complete the compound motion according to the set parameters, and stop automatically after the end.

[0052] The working principle of the technical solution provided by this utility model is as follows:

[0053] In use, first place the test tube containing the erythrocyte sedimentation rate (ESR) sample into the clamping assembly, adjust the tilt angle to the preset value, select the mixing mode on the touch screen, input the rotation speed and time, and the device will start. The internal drive motor of the main body 1 is fixedly connected to the bottom of the mixing platform 2. Starting the drive motor enables the mixing platform 2 to rotate horizontally. The mixing platform 2 includes a bottom disc and two side plates. Two rotating shafts 3 are installed parallel between the side plates, and one side of each rotating shaft 3 is fixedly connected to a servo motor to drive the rotation of the rotating shafts 3. The test tube is clamped between the two clamps. Between the holding plates 6, the test tube passes through the positioning sleeves 9, forming a three-point fixed test tube to maintain its stability in the mixing state. The servo motor precisely controls the speed and angular displacement, and the rotating shaft 3 rotates back and forth within a preset angle range, mixing the solution in the test tube. The hubs 4 on the two rotating shafts 3 are staggered to ensure that the mixing work on both sides does not interfere with each other. The test tube on the rotating shaft 3 swings with the shaft, and the solution generates shaking and eddies due to inertia, simulating the left and right shaking motion of an artificial wrist, ensuring a stable swing amplitude. This avoids hemolysis caused by violent shaking and promotes the mixing process through regular reciprocating motion. The solution is uniformly mixed, meeting the requirements of mildness and uniformity in sample processing in experiments. The angle of the adjusting rod 5 can accommodate test tubes of different lengths. Furthermore, the adjusting rod 5 has evenly distributed lightweight grooves 7 for easy adjustment. The clamping pieces 6 are evenly distributed around the circumference, forming a clamping and placement cavity. The bottom of the test tube is inserted into the clamping piece 6. Utilizing the elastic deformation of the clamping piece 6, it can not only accommodate test tubes of different thicknesses but also prevent slippage after clamping. Similarly, the other end of the test tube is placed... Within the clamping piece 6 on the other side, the test tube is securely placed. Then, the positioning sleeve 9 is clamped onto the outer wall of the test tube. The limiting rod 8 and the positioning sleeve 9 also have elastic properties, and the limiting rod 8 has an S-shaped movement, which can adapt to different distances between the test tube and the hub 4, satisfying the three-point clamping of the test tube. Furthermore, the adjusting rod 5, clamping piece 6, limiting rod 8, and positioning sleeve 9 are all made of elastic silicone material, which can adapt to different sizes of test tubes and avoid damage to the test tube when clamping. This device can ensure that the anticoagulant is fully mixed with the blood without damaging the red blood cells, ensuring that the erythrocyte sedimentation rate test results truly reflect the pathological state.

[0054] This utility model encompasses any substitutions, modifications, equivalent methods, and solutions made within the spirit and scope of this utility model. To provide the public with a thorough understanding of this utility model, specific details are described in detail in the following preferred embodiments; however, those skilled in the art will fully understand this utility model even without these detailed descriptions. Furthermore, to avoid unnecessary confusion regarding the essence of this utility model, well-known methods, processes, procedures, components, and circuits are not described in detail.

[0055] The above description is only a preferred embodiment of the present utility model. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the principle of the present utility model, and these improvements and modifications should also be considered within the protection scope of the present utility model.

Claims

1. A erythrocyte sedimentation rate (ESR) mixer, comprising a body, characterized in that, The machine body is rotatably connected to a mixing platform, and a pair of rotating shafts are rotatably connected to the mixing platform; A clamping assembly for clamping test tubes for erythrocyte sedimentation rate (ESR) testing, the clamping assembly being connected to the rotating shaft; The clamping assembly includes a hub fixedly connected to the rotating shaft, symmetrically distributed adjusting rods fixedly connected to the outer wall of the hub, clamping plates arranged in a circular pattern fixedly connected to the free end of the adjusting rods, and a limiting rod fixedly connected to the outer wall of the hub, with a positioning sleeve fixedly connected to the free end of the limiting rod. The adjusting rod, the clamping plate, the limiting rod, and the positioning sleeve are all made of elastic silicone.

2. The blood sedimentation mixer of claim 1, wherein The mixing platform includes a bottom disc and vertical plates fixed to both sides of the disc, with two rotating shafts installed parallel between the two vertical plates.

3. The blood sedimentation mixer of claim 2, wherein The hubs on the outer wall of the pair of rotating shafts are staggered and evenly distributed on the outer wall of the rotating shafts.

4. The blood sedimentation mixer of claim 2, wherein The adjusting rod is a curved elastic structure with a circular cross-section, and the bent part of the adjusting rod is provided with uniformly distributed lightweight grooves.

5. The blood sedimentation mixer of claim 2, wherein The clamping piece is a curved elastic structure with an S-shaped cross-section and an outward tilting angle at its free end.

6. The blood sedimentation mixer of claim 2, wherein The limiting rod is a curved elastic structure with a circular cross-section, and the bending part of the limiting rod is provided with uniformly distributed weakening grooves.

7. The blood sedimentation mixer of claim 2, wherein The position of the limiting rod corresponds to the center between the adjusting rod and the positioning sleeve, and both ends of the positioning sleeve have an outward tilting angle.

8. The blood sedimentation mixer of claim 2, wherein, The adjusting rod and the clamping piece are manufactured as a single piece, and the limiting rod and the positioning sleeve are also manufactured as a single piece.

9. The blood sedimentation mixer of claim 2, wherein, A servo motor is provided on one side of the mixing platform, and the output shaft of the servo motor is fixedly connected to the rotation shaft.