A sampling device for flow cytometer

Abstract

This utility model relates to the field of sampling technology for flow cytometers, specifically a sampling device for flow cytometers, including a base and a test tube tray. A sampler is fixedly mounted on the test tube tray. A toothed plate meshing with a first gear is movably mounted on the top of a support plate. A lead screw connected to the base is movably mounted on the toothed plate. A vertical plate connected to the lead screw is mounted on the base. A turntable is fixedly mounted on one end of the lead screw. This utility model, through the setting of a rotating structure, changes the traditional method of manually placing test tubes under the sampler. Therefore, even when there are many types of cell stock solutions, the sampler can orderly sample the cell stock solutions in the test tubes by rotating the test tube tray. The advantage of this structure is that it avoids the tedious procedure of manually changing test tubes, thus not affecting the speed of cell detection sampling, thereby improving sampling efficiency and meeting the needs of experiments.

Description

Technical Field

[0001] This utility model relates to a sampling device for flow cytometers, and more particularly to a sampling device for flow cytometers, belonging to the field of sampling technology for flow cytometers. Background Technology

[0002] Flow cytometers are devices for the automated analysis and sorting of cells; they can rapidly measure, store, and display a range of important biophysical and biochemical parameters of dispersed cells suspended in a liquid, and can sort out specified cell subpopulations based on a pre-selected range of parameters.

[0003] Traditional flow cytometers have a simple sampling device structure. When sampling cell stock solutions, a sampler is needed to draw the cell stock solution, which is usually placed in a test tube. When there are many types of cell stock solutions to be sampled, manually changing test tubes is not particularly convenient, which affects the speed of cell detection sampling, reduces sampling efficiency, and cannot meet the needs of experiments.

[0004] Therefore, there is an urgent need to improve the sampling device used in flow cytometry to solve the aforementioned problems. Utility Model Content

[0005] The purpose of this invention is to provide a sampling device for flow cytometers. By designing a rotating structure, the traditional method of manually placing test tubes under the sampler is changed. Therefore, even when there are many types of cell stock solutions, the sampler can orderly sample the cell stock solutions in the test tubes by rotating the test tube placement tray. The advantage of this structure is that it avoids the tedious procedure of manually changing test tubes, thus not affecting the speed of cell detection sampling, thereby improving sampling efficiency and meeting the needs of experiments.

[0006] To achieve the above objectives, the main technical solutions adopted by this utility model include: A sampling device for a flow cytometer includes a base and a test tube tray. A sampler is fixedly mounted on the test tube tray. The test tube tray has a rotating structure, which includes a rotating shaft fixedly mounted on the eastern side of the base and connected to the test tube tray. A first gear is fixedly mounted on the rotating shaft. A support plate is fixedly mounted on one side of the rotating shaft. A toothed plate that meshes with the first gear is movably mounted on the top of the support plate. A lead screw connected to the base is movably mounted on the toothed plate. A vertical plate connected to the lead screw is mounted on the base. A turntable is fixedly mounted on one end of the lead screw.

[0007] Preferably, a fixing plate is fixedly installed at one end of the base, a first electric telescopic rod is fixedly installed on the top of the fixing plate, a first control switch electrically connected to the first electric telescopic rod is provided on the fixing plate, a locking tooth is installed on the first electric telescopic rod, and a second gear that meshes with the locking tooth is fixedly installed on the lead screw.

[0008] Preferably, a fixing block is fixedly installed on the first electric telescopic rod, and a fixing sleeve connected to the fixing block is fixedly installed at one end of the locking tooth. Both the fixing block and the fixing sleeve have connecting holes, and an insert rod is movably installed inside the connecting hole. A locking bolt is fixedly installed at one end of the insert rod.

[0009] Preferably, the support plate has a groove, and a slide rod connected to the toothed plate is movably installed inside the groove.

[0010] Preferably, a plurality of limiting plates are fixedly installed on the base, a push block is provided between the limiting plates, a limiting rod is fixedly installed at one end of the push block, and limiting holes adapted to the limiting rod are provided on both the support plate and the slide rod.

[0011] Preferably, both the limiting plate and the push block are provided with embedding holes, and the limiting plate is equipped with an embedding rod connected to the push block.

[0012] Preferably, a second electric telescopic rod is fixedly installed at one end of the base, a second control switch electrically connected to the second electric telescopic rod is provided on the base, and a protective cover is fixedly installed at the output end of the second electric telescopic rod.

[0013] This utility model has at least the following beneficial effects: By using a rotating structure, the traditional method of manually placing test tubes under the sampler is changed. Therefore, even when there are many types of cell stock solutions, the sampler can orderly sample the cell stock solutions in the test tubes by rotating the test tube placement tray. The advantage of this structure is that it avoids the tedious procedure of manually changing test tubes, thus not affecting the speed of cell detection sampling, thereby improving sampling efficiency and meeting the needs of experiments. Attached Figure Description

[0014] The accompanying drawings, which are included to provide a further understanding of this application and form part of this application, illustrate exemplary embodiments of this application and are used to explain this application, but do not constitute an undue limitation of this application. In the drawings: Figure 1 This is a schematic diagram of the overall structure of this utility model; Figure 2 This is a schematic diagram of the lead screw structure of this utility model; Figure 3 For the present utility model Figure 2 Enlarged view of point A in the middle; Figure 4 For the present utility model Figure 2 Enlarged view at point B in the middle; Figure 5 For the present utility model Figure 2 Enlarged view of point C in the middle.

[0015] In the diagram: 1. Base; 2. Test tube tray; 3. Sampler; 4. Rotating structure; 5. Shaft; 6. First gear; 7. Support plate; 8. Gear plate; 9. Lead screw; 10. Vertical plate; 11. Turntable; 12. Fixing plate; 13. First electric telescopic rod; 14. First control switch; 15. Clamping tooth; 16. Second gear; 17. Fixing block; 18. Fixing sleeve; 19. Connecting hole; 20. Insert rod; 21. Clamp; 22. Slide groove; 23. Slide rod; 24. Limiting plate; 25. Push block; 26. Limiting rod; 27. Limiting hole; 28. Embedding hole; 29. ​​Embedding rod; 30. Second electric telescopic rod; 31. Second control switch; 32. Protective cover. Detailed Implementation

[0016] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present utility model without creative effort are within the protection scope of the present utility model.

[0017] like Figures 1-5 As shown in this embodiment, a sampling device for a flow cytometer is provided.

[0018] A sampling device for a flow cytometer includes a base 1 and a test tube tray 2. A sampler 3 is fixedly mounted on the test tube tray 2. A rotating structure 4 is provided on the test tube tray 2. The rotating structure 4 includes a rotating shaft 5 fixedly mounted on the east side of the base 1 and connected to the test tube tray 2. A first gear 6 is fixedly mounted on the rotating shaft 5. A support plate 7 is fixedly mounted on one side of the rotating shaft 5. A toothed plate 8 that meshes with the first gear 6 is movably mounted on the top of the support plate 7. A lead screw 9 connected to the base 1 is movably mounted on the toothed plate 8. A vertical plate 10 connected to the lead screw 9 is mounted on the base 1. A turntable 11 is fixedly mounted on one end of the lead screw 9.

[0019] By using the rotating structure 4, the traditional method of manually placing test tubes under the sampler 3 is changed. Therefore, even when there are many types of cell stock solutions, the sampler 3 can orderly sample the cell stock solutions in the test tubes by rotating the test tube placement tray 2. The advantage of this structure is that it avoids the tedious procedure of manually changing test tubes, thus not affecting the speed of cell detection sampling, thereby improving sampling efficiency and meeting the needs of experiments.

[0020] like Figures 1-5 As shown, a fixing plate 12 is fixedly installed at one end of the base 1, and a first electric telescopic rod 13 is fixedly installed on the top of the fixing plate 12. A first control switch 14 electrically connected to the first electric telescopic rod 13 is provided on the fixing plate 12. A locking tooth 15 is installed on the first electric telescopic rod 13. A second gear 16 meshing with the locking tooth 15 is fixedly installed on the lead screw 9. A fixing block 17 is fixedly installed on the first electric telescopic rod 13. A fixing sleeve 18 connected to the fixing block 17 is fixedly installed at one end of the locking tooth 15. Both the fixing block 17 and the fixing sleeve 18 are provided with connection holes 19. An insert rod 20 is movably installed inside the connection hole 19. A latch 21 is fixedly installed at one end of the insert rod 20.

[0021] The arrangement of the fixed plate 12, the first electric telescopic rod 13, the first control switch 14, the locking tooth 15, and the second gear 16 allows the first electric telescopic rod 13 to extend and move, causing the locking tooth 15 to rise. When the locking tooth 15 engages with the second gear 16, it limits the movement of the lead screw 9, preventing accidental rotation and potential displacement of the test tubes in the test tube placement tray 2. This is especially important if the test tube placement tray 2 is being sampled, as it could be damaged by the test tubes. The first control switch 14 can then retract the first electric telescopic rod 13, disengaging the locking tooth 15 from the second gear 16. At this point, the lead screw 9 can be rotated normally. With the setting of the fixing block 17, fixing sleeve 18, connecting hole 19, insert rod 20 and buckle 21, after the fixing block 17 is inserted into the inside of the fixing sleeve 18, the second electric telescopic rod 30 is inserted into the inside of the connecting hole 19 and the insert rod 20 is rotated. When the angle of the buckle 21 is adjusted to be perpendicular to the angle of the connecting hole 19, the fixing block 17 can be fixed inside the fixing sleeve 18 to prevent it from falling off. When the angle of the buckle 21 is adjusted to be consistent with the angle of the connecting hole 19, the insert rod 20 can be pulled out from the inside of the connecting hole 19, so that personnel can easily disassemble and replace the clip 15 when it is damaged.

[0022] like Figures 1-5As shown, a sliding groove 22 is provided on the support plate 7, and a sliding rod 23 connected to the toothed plate 8 is movably installed inside the sliding groove 22. Multiple limiting plates 24 are fixedly installed on the base 1, and a push block 25 is provided between the limiting plates 24. A limiting rod 26 is fixedly installed at one end of the push block 25. Both the support plate 7 and the sliding rod 23 are provided with limiting holes 27 that are adapted to the limiting rod 26. Both the limiting plate 24 and the push block 25 are provided with embedding holes 28. An embedding rod 29 connected to the push block 25 is installed on the limiting plate 24.

[0023] By using the groove 22 and the slide rod 23, the friction between the toothed plate 8 and the support plate 7 can be reduced, making the toothed plate 8 slide more smoothly on the support plate 7. Therefore, it not only reduces the wear between the toothed plate 8 and the support plate 7, but also makes it easier for personnel to rotate the turntable 11. By using the limiting plate 24, the push block 25, the limiting rod 26, and the limiting hole 27, the push block 25 is pushed to move so that it can drive the limiting rod 26 to move. When the limiting rod 26 moves and inserts into the limiting hole 27, it can connect the support plate 7 and the slide rod 23 together, thereby limiting the slide rod 23 and preventing the toothed plate 8 from moving due to the slide rod 23 sliding. Therefore, the stability of the slide bar 23 inside the support plate 7 can be improved. Pulling the push block 25 will cause the limiting rod 26 to disengage from the limiting hole 27, thereby allowing the slide bar 23 to move normally. With the setting of the embedding hole 28 and the embedding rod 29, when the embedding rod 29 is inserted into the embedding hole 28 to connect the push block 25 with the limiting plate 24, the push block 25 can be limited, thereby improving the stability of the push block 25 between the limiting plates 24 and preventing the push block 25 from sliding between the limiting plates 24, which would affect the limiting of the limiting rod 26. After the embedding rod 29 is pulled out from the embedding hole 28, the push block 25 can be pushed and pulled.

[0024] like Figures 1-5 As shown, a second electric telescopic rod 30 is fixedly installed at one end of the base 1, and a second control switch 31 electrically connected to the second electric telescopic rod 30 is provided on the base 1. A protective cover 32 is fixedly installed at the output end of the second electric telescopic rod 30.

[0025] With the configuration of the second electric telescopic rod 30, the second control switch 31, and the protective cover 32, the second electric telescopic rod 30 can extend and retract under the control of the second control switch 31. When the second electric telescopic rod 30 extends, it can move the protective cover 32 to the position of the sampler 3, and the protective cover 32 can cover the sampler 3, thereby protecting the sampler 3 and preventing it from being accidentally touched and damaged when not in use. When the second electric telescopic rod 30 retracts, it can move the protective cover 32 away from the position of the sampler 3, so that the sampler 3 can be used normally.

[0026] In this embodiment, as Figures 1-5 As shown in the figure, the working process of a sampling device for a flow cytometer provided in this embodiment is as follows: First, after placing various cell stock solutions into the test tube placement tray 2, the sampler 3 can sample the stock solutions in the test tubes directly below it. After sampling, the turntable 11 is rotated, which drives the lead screw 9 to rotate. The toothed plate 8 can move back and forth on the support plate 7 under the drive of the lead screw 9. Due to the connection between the toothed plate 8 and the first gear 6, the first gear 6 can start to rotate under its drive while the toothed plate 8 moves. When the first gear 6 rotates, it causes the rotating shaft 5 to drive the test tube placement tray 2 to rotate. The rotation of the test tube placement tray 2 can rotate and adjust the test tubes inside it, so that the next test tube to be sampled can be rotated to the bottom of the sampler 3, and the next type of sampling and testing can be carried out.

[0027] The foregoing description illustrates and describes several preferred embodiments of the present invention. However, as previously stated, it should be understood that the present invention is not limited to the forms disclosed herein and should not be construed as excluding other embodiments. It can be used in various other combinations, modifications, and environments, and can be altered within the scope of the inventive concept described herein through the foregoing teachings or techniques or knowledge in related fields. Any modifications and variations made by those skilled in the art that do not depart from the spirit and scope of the present invention should be within the protection scope of the appended claims.

Claims

1. A sampling device for a flow cytometer, comprising a base (1) and a test tube placement disc (2) on which a sampling instrument (3) is fixedly installed, characterized in that: The test tube placement tray (2) is provided with a rotating structure (4). The rotating structure (4) includes a rotating shaft (5) fixedly installed on the east side of the base (1) and connected to the test tube placement tray (2). A first gear (6) is fixedly installed on the rotating shaft (5). A support plate (7) is fixedly installed on one side of the rotating shaft (5). A toothed plate (8) that meshes with the first gear (6) is movably installed on the top of the support plate (7). A lead screw (9) connected to the base (1) is movably installed on the toothed plate (8). A vertical plate (10) connected to the lead screw (9) is installed on the base (1). A turntable (11) is fixedly installed at one end of the lead screw (9).

2. A sampling device for a flow cytometer according to claim 1, wherein: A fixing plate (12) is fixedly installed at one end of the base (1), and a first electric telescopic rod (13) is fixedly installed on the top of the fixing plate (12). A first control switch (14) electrically connected to the first electric telescopic rod (13) is provided on the fixing plate (12), and a locking tooth (15) is installed on the first electric telescopic rod (13). A second gear (16) meshing with the locking tooth (15) is fixedly installed on the lead screw (9).

3. A sampling device for a flow cytometer according to claim 2, wherein: A fixing block (17) is fixedly installed on the first electric telescopic rod (13). A fixing sleeve (18) connected to the fixing block (17) is fixedly installed at one end of the locking tooth (15). Both the fixing block (17) and the fixing sleeve (18) are provided with connecting holes (19). A plug rod (20) is movably installed inside the connecting hole (19). A bolt (21) is fixedly installed at one end of the plug rod (20).

4. The sampling apparatus for a flow cytometer of claim 1, wherein: The support plate (7) is provided with a groove (22), and a slide rod (23) connected to the toothed plate (8) is movably installed inside the groove (22).

5. A sampling device for a flow cytometer according to claim 4, wherein: Multiple limiting plates (24) are fixedly installed on the base (1). Push blocks (25) are provided between the limiting plates (24). A limiting rod (26) is fixedly installed at one end of the push block (25). Limiting holes (27) adapted to the limiting rod (26) are opened on both the support plate (7) and the slide rod (23).

6. A sampling device for a flow cytometer according to claim 5, wherein: Both the limiting plate (24) and the push block (25) are provided with embedding holes (28), and the limiting plate (24) is provided with an embedding rod (29) connected to the push block (25).

7. A sampling apparatus for a flow cytometer according to claim 1, wherein: A second electric telescopic rod (30) is fixedly installed at one end of the base (1). A second control switch (31) electrically connected to the second electric telescopic rod (30) is provided on the base (1). A protective cover (32) is fixedly installed at the output end of the second electric telescopic rod (30).

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