A high-performance liquid chromatograph equipped with an automated syringe cleaning assembly

Abstract

This utility model discloses a high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly, belonging to the field of liquid chromatography technology. This high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly includes an automatic injection liquid chromatograph with an automatic injection mechanism inside. A drying mechanism and a cleaning mechanism are respectively located on both sides of the bottom of the automatic injection liquid chromatograph. The cleaning mechanism includes a cleaning chamber, the bottom of which is connected to the bottom of the automatic injection liquid chromatograph. The cleaning chamber has a cleaning tank inside, and a cavity is formed at the bottom of the cleaning tank. An ultrasonic transducer is installed at the top of the cavity. A lid is interference-fitted to the top of the cleaning chamber. The drying mechanism includes a drying chamber, the bottom of which is connected to the other side of the bottom of the automatic injection liquid chromatograph. A drip screen is provided at the bottom of the drying chamber. This utility model can effectively improve the practicality of the automatic injection needle high-performance liquid chromatograph.

Description

Technical Field

[0001] This utility model relates to the field of liquid chromatography technology, specifically a high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly. Background Technology

[0002] High-performance liquid chromatography (HPLC) is a core instrument in analytical chemistry used for substance separation and quantitative detection, and is widely used in pharmaceutical research and development, food testing, environmental monitoring, and other scenarios. The autosampler is a key component of the injection system, responsible for accurately extracting samples and injecting them into the chromatographic column.

[0003] Based on the above, the inventors have discovered the following problems: Most existing automated syringe liquid chromatographs use bolts to fix the syringes. Each time the syringe is disassembled and reassembled, a special tool is needed to tighten the bolts. However, the internal operating space of the equipment is limited, and using tools to tighten the bolts can easily damage other internal components. Therefore, careful operation is required, resulting in a significant time commitment during disassembly and reassembly. Furthermore, cleaning the syringe relies entirely on manual operation, which is inefficient. Operators must first disassemble the removed syringe into multiple components such as the push rod, syringe tube, and sealing ring, and then wipe each component individually with reagents. The manual wiping and soaking operations alone take several minutes during the entire cleaning process. Combined with the time spent on disassembly, the total time for a single cleaning cycle is even longer, significantly impacting detection efficiency.

[0004] Therefore, in view of this, we have studied and improved the existing structure and its shortcomings, and provided a high-performance liquid chromatograph equipped with an automatic injection needle cleaning component, in order to achieve a more practical purpose. Utility Model Content

[0005] The purpose of this invention is to provide a high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly, in order to solve the problems mentioned in the background art, that the injection needles of existing automatic injection needle liquid chromatographs are mostly fixed with bolts, which is time-consuming to install and remove, and the cleaning process of the injection needles also takes a long time.

[0006] In view of the above problems, the technical solution proposed by this utility model is as follows:

[0007] A high-performance liquid chromatograph (HPLC) equipped with an automated injection needle cleaning assembly includes an automated injection HPLC with an internal automated injection mechanism. The HPLC has a drying mechanism and a cleaning mechanism on either side of its bottom. The cleaning mechanism includes a cleaning chamber connected to the bottom of the HPLC, with a cleaning tank inside. A cavity is formed at the bottom of the cleaning tank, and an ultrasonic transducer is installed at the top of the cavity. A cover is interference-fitted to the top of the cleaning chamber. The drying mechanism includes a drying chamber connected to the other side of the HPLC bottom. A drip screen is provided at the bottom of the drying chamber, and a cover plate is interference-fitted to the top of the drying chamber. A hot air blower is installed on the top of the cover plate, and the output of the hot air blower extends through the cover plate into the interior of the drying chamber.

[0008] Furthermore, an ultrasonic generator is fixedly installed at the bottom of the cavity, and the ultrasonic generator and the ultrasonic transducer are electrically connected by a wire.

[0009] The beneficial effect of adopting the above-mentioned further solution is that the ultrasonic generator at the bottom of the cavity provides a high-frequency electrical signal to the ultrasonic transducer through a wire, so that the ultrasonic transducer converts electrical energy into mechanical vibration, thereby generating dense bubbles in the cleaning liquid in the cleaning tank. The impact force generated when the bubbles burst can penetrate into the inner wall of the injection needle and the gap of the needle tip, effectively removing stubborn residual samples. Compared with traditional rinsing and wiping methods, the cleaning is more thorough. Moreover, by adjusting the ultrasonic frequency to an appropriate value, it will not damage the injection needle, ensuring the service life of the injection needle and the injection accuracy.

[0010] Furthermore, an L-shaped drain pipe is inserted into the bottom side of the cleaning tank, and the top end of the L-shaped drain pipe is connected to the bottom side of the cleaning tank.

[0011] The beneficial effect of adopting the above-mentioned further solution is that the L-shaped drain pipe on the bottom side of the cleaning tank can be directly connected to the cleaning tank. After cleaning, there is no need to tilt the cleaning tank. Waste cleaning liquid can be quickly discharged through the L-shaped drain pipe, which is convenient to operate and avoids the spillage of cleaning liquid and contamination of equipment.

[0012] Furthermore, several exhaust holes are provided on both sides of the upper end of the drying box, and a water outlet pipe is installed on the bottom side of the drying box.

[0013] The beneficial effects of adopting the above-mentioned further solution are that the exhaust vent at the top of the drying oven can promptly discharge the hot and humid air generated when the hot air blower is working, avoiding the accumulation of moisture in the drying oven and affecting the drying efficiency. At the same time, it balances the air pressure inside and outside the oven and prevents the cover plate from becoming loose due to excessive pressure inside the oven. The water outlet pipe on the bottom side discharges the water that drips from the injection needle before drying.

[0014] Furthermore, the automatic injection mechanism includes a slide rod disposed inside the automatic injection liquid chromatograph. A movable block is slidably sleeved on the slide rod. One side of the movable block is slidably connected to the inner wall of the automatic injection liquid chromatograph. A pair of clamping seats are fixedly installed on the outer side of the movable block. A locking seat is hinged to one end of each clamping seat. A first knob is movably inserted into one side of the locking seat. One end of the first knob is threadedly connected to the outer side of one end of the clamping seat. An injection needle is inserted between the two pairs of clamping seats and the locking seats. A push rod is slidably installed inside the injection needle.

[0015] The beneficial effects of adopting the above-mentioned further solution are that the slide bar of the automatic injection mechanism provides a sliding guide for the moving block, ensuring that the moving block drives the injection needle to move smoothly; the clamping seat and the locking seat cooperate to firmly clamp the injection needle, and the first knob screw locks it, which can prevent the injection needle from loosening or shifting during movement or injection, without the need to use special tools; the push rod inside the injection needle can realize the extraction and ejection of the sample, ensuring that the injection volume is accurate and controllable.

[0016] Furthermore, a connecting block is installed on the upper side of one side of the movable block, and a light rod is fixedly installed on the bottom side of the connecting block. The bottom end of the light rod is connected to the top end of one of the clamping seats. A movable seat is slidably installed on the light rod. An electric telescopic rod is inserted into one end of the connecting block. The output end of the electric telescopic rod is connected to the upper end of the movable seat. The top end of the push rod extends into the interior of the movable seat. A second knob is movably inserted into one side of the movable seat. One end of the second knob is threadedly connected to the upper side of the push rod. The beneficial effect of adopting the above-mentioned further solution is that the light rod on the bottom side of the connecting block provides a lifting guide for the movable seat. The electric telescopic rod can drive the movable seat to rise and fall smoothly along the light rod, thereby driving the push rod to slide inside the injection needle, realizing automated sample extraction and ejection, and avoiding injection volume errors caused by manual operation. The second knob can firmly fix the push rod and the movable seat, preventing the push rod and the movable seat from sliding relative to each other, ensuring accurate lifting stroke of the push rod, further improving injection accuracy. Moreover, by setting the second knob, there is no need to use professional tools for disassembly.

[0017] Furthermore, the automatic injection mechanism also includes a servo motor and a first synchronous wheel. The central shaft of one side of the first synchronous wheel is rotatably connected to the inner bottom side of the automatic injection liquid chromatograph. The servo motor is embedded in the upper side of the inside of the automatic injection liquid chromatograph. The output end of the servo motor is fitted with a second synchronous wheel. A synchronous belt is wound between the first and second synchronous wheels. One side of the synchronous belt is fixedly connected to one side of the moving block.

[0018] The beneficial effects of adopting the above-mentioned further solution are that the servo motor can provide stable and controllable power, and the second synchronous pulley at its output end drives the first synchronous pulley to rotate through the synchronous belt, thereby causing the synchronous belt to drive the moving block to move along the slide bar; the speed and direction of the servo motor are controllable, which can realize the precise positioning of the moving block, and with the bottom turntable of the automatic injection liquid chromatograph, it is convenient for sampling and injection operations.

[0019] Compared with the prior art, the beneficial effects of this utility model are as follows: This high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly enables automated injection of the injection needle, improving experimental efficiency; the cleaning mechanism and drying mechanism at the bottom form a "cleaning-drying" linkage process; the cleaning tank in the cleaning chamber is used to hold the cleaning solution, and the ultrasonic transducer can generate ultrasonic waves to deeply clean the injection needle, removing residual samples and avoiding cross-contamination; the hot air blower in the drying chamber can quickly dry the cleaned injection needle, preventing moisture from affecting the accuracy of subsequent injections; both the lid of the cleaning chamber and the cover of the drying chamber are interference-fitted for easy opening by the user, achieving overall automatic cleaning of the injection needle. Automated cleaning and drying ensure the accuracy of experimental results and reduce manual operation steps. The slide bar of the automatic injection mechanism provides a sliding guide for the moving block, ensuring that the moving block drives the injection needle to move smoothly. The clamping seat and locking seat cooperate to firmly clamp the injection needle. The first knob is threaded to lock, which can prevent the injection needle from loosening or shifting during movement or injection, without the need for special tools. The push rod inside the injection needle can realize the extraction and ejection of the sample, ensuring accurate and controllable injection volume. The second knob can firmly fix the push rod and the moving seat, preventing the push rod and the moving seat from sliding relative to each other, ensuring accurate lifting stroke of the push rod, further improving injection accuracy. Moreover, by setting the second knob, disassembly is also not required to use special tools. Attached Figure Description

[0020] Figure 1 A three-dimensional structural diagram of a high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly, as disclosed in an embodiment of this utility model. Figure 1 ;

[0021] Figure 2 This is a three-dimensional structural diagram of the internal structure of the high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly disclosed in an embodiment of the present invention.

[0022] Figure 3 A three-dimensional structural diagram of a high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly, as disclosed in an embodiment of this utility model. Figure 2 ;

[0023] Figure 4 This is a front cross-sectional view of the cleaning chamber of a high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly, as disclosed in an embodiment of the present invention.

[0024] Figure 5 This invention discloses a high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly. Figure 2 An enlarged schematic diagram of the A structure.

[0025] In the diagram: 1. Automatic liquid chromatograph with autosampler; 2. Drying mechanism; 201. Drying oven; 202. Exhaust vent; 203. Cover plate; 204. Hot air blower; 205. Drip screen; 206. Water outlet pipe; 3. Cleaning mechanism; 301. Cleaning box; 302. Box cover; 303. L-shaped drain pipe; 304. Ultrasonic transducer; 305. Ultrasonic generator; 306. Cavity; 307. Cleaning tank; 4. Automatic 401. Slide bar; 402. Servo motor; 403. Second synchronous pulley; 404. Moving block; 405. Synchronous belt; 406. First synchronous pulley; 407. Clamping seat; 408. Locking seat; 409. First knob; 410. Injection needle; 411. Smooth rod; 412. Moving seat; 413. Second knob; 414. Push rod; 415. Electric telescopic rod; 416. Connecting block. Detailed Implementation

[0026] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0027] Please see Figure 1 - Figure 5 This utility model provides a technical solution: a high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly, comprising an automatic injection liquid chromatograph 1, an automatic injection mechanism 4 inside the automatic injection liquid chromatograph 1, a drying mechanism 2 and a cleaning mechanism 3 respectively located on both sides of the bottom end of the automatic injection liquid chromatograph 1, the cleaning mechanism 3 including a cleaning chamber 301, the bottom side of the cleaning chamber 301 being connected to the bottom side of the automatic injection liquid chromatograph 1, and a cleaning tank 307 inside the cleaning chamber 301, the interior of the cleaning chamber 301 being located at the bottom of the cleaning tank 307. The cleaning chamber 301 has a cavity 306 at one end, and an ultrasonic transducer 304 is installed at the top of the cavity 306. The upper end of the cleaning chamber 301 is press-fitted with a cover 302. The drying mechanism 2 includes a drying chamber 201. The bottom side of the drying chamber 201 is connected to the other side of the bottom of the automatic injection liquid chromatograph 1. The bottom of the interior of the drying chamber 201 is provided with a drip net 205. The upper end of the drying chamber 201 is press-fitted with a cover plate 203. A hot air blower 204 is installed at the upper end of the cover plate 203. The output end of the hot air blower 204 extends through the cover plate 203 into the interior of the drying chamber 201.

[0028] As an embodiment of this utility model, an ultrasonic generator 305 is further fixedly installed at the bottom of the cavity 306. The ultrasonic generator 305 and the ultrasonic transducer 304 are electrically connected by a wire. The ultrasonic generator 305 at the bottom of the cavity 306 provides a high-frequency electrical signal to the ultrasonic transducer 304 through the wire, so that the ultrasonic transducer 304 converts electrical energy into mechanical vibration, thereby generating dense bubbles in the cleaning liquid of the cleaning tank 307. The impact force generated when the bubbles burst can penetrate into the inner wall of the injection needle 410 and the gap of the needle tip, effectively removing stubborn residual samples. Compared with traditional rinsing and wiping methods, the cleaning is more thorough. Moreover, by adjusting the ultrasonic frequency to an appropriate value, it will not damage the injection needle 410, ensuring the service life and injection accuracy of the injection needle 410.

[0029] As an embodiment of this utility model, an L-shaped drain pipe 303 is inserted into the bottom side of the cleaning tank 301. The top end of the L-shaped drain pipe 303 is connected to the bottom side of the cleaning tank 307. The L-shaped drain pipe 303 on the bottom side of the cleaning tank 301 can be directly connected to the cleaning tank 307. After cleaning, there is no need to pour out the cleaning tank 301. Waste cleaning liquid can be quickly discharged through the L-shaped drain pipe 303. The operation is convenient and avoids the cleaning liquid from spilling and contaminating the equipment.

[0030] As an embodiment of this utility model, further, several exhaust holes 202 are provided on both sides of the upper end of the drying oven 201, and a water outlet pipe 206 is installed on the bottom side of the drying oven 201. The exhaust holes 202 at the upper end of the drying oven 201 can timely discharge the hot and humid air generated when the hot air blower 204 is working, so as to avoid the accumulation of moisture in the drying oven 201 and affect the drying efficiency. At the same time, it balances the air pressure inside and outside the oven and prevents the cover plate 203 from becoming loose due to excessive pressure inside the oven. The water outlet pipe 206 on the bottom side discharges the water dripping from the injection needle 410 before drying.

[0031] As an embodiment of this utility model, the automatic injection mechanism 4 further includes a slide rod 401, which is disposed inside the automatic injection liquid chromatograph 1. A movable block 404 is slidably sleeved on the slide rod 401. One side of the movable block 404 is slidably connected to the inner wall of the automatic injection liquid chromatograph 1. A pair of clamping seats 407 are fixedly installed on the outer side of the movable block 404. A locking seat 408 is hinged to one end of each clamping seat 407. A first knob 409 is movably inserted into one side of the locking seat 408. One end of the first knob 409 is threadedly connected to the outer side of one end of the clamping seat 407. The two pairs of clamping seats 407 are further configured to be connected to each other. A sample injection needle 410 is inserted between the 07 and the locking seat 408. A push rod 414 is slidably installed inside the sample injection needle 410. The slide rod 401 of the automatic injection mechanism 4 provides a sliding guide for the moving block 404, ensuring that the moving block 404 drives the sample injection needle 410 to move smoothly. The clamping seat 407 and the locking seat 408 cooperate to firmly clamp the sample injection needle 410. It is locked by the first knob 409, which can prevent the sample injection needle 410 from loosening or shifting during movement or injection, without the need for special tools. The push rod 414 inside the sample injection needle 410 can realize the extraction and ejection of the sample, ensuring that the injection volume is accurate and controllable.

[0032] As an embodiment of this utility model, a connecting block 416 is further installed on the upper side of one side of the movable block 404, and a light rod 411 is fixedly installed on the bottom side of the connecting block 416. The bottom end of the light rod 411 is connected to the top end of one of the clamping seats 407. A movable seat 412 is slidably installed on the light rod 411. An electric telescopic rod 415 is inserted into one end of the connecting block 416. The output end of the electric telescopic rod 415 is connected to the upper end of the movable seat 412. The top end of the push rod 414 extends into the interior of the movable seat 412. A second knob 413 is movably inserted into one side of the movable seat 412. One end of the second knob 413 is connected to the upper end of the push rod 414. The connecting block 416 has a threaded connection on one side. The smooth rod 411 on the bottom side of the connecting block 416 provides a lifting guide for the moving seat 412. The electric telescopic rod 415 can drive the moving seat 412 to rise and fall smoothly along the smooth rod 411, thereby driving the push rod 414 to slide inside the injection needle 410, realizing automated sample extraction and ejection, avoiding sample volume errors caused by manual operation. The second knob 413 can firmly fix the push rod 414 and the moving seat 412, preventing the push rod 414 and the moving seat 412 from sliding relative to each other, ensuring the precise lifting stroke of the push rod 414, further improving the sample injection accuracy. Moreover, by setting the second knob 413, there is no need to use professional tools for disassembly.

[0033] As an embodiment of this utility model, the automatic injection mechanism 4 further includes a servo motor 402 and a first synchronous wheel 406. One side of the central shaft of the first synchronous wheel 406 is rotatably connected to one side of the inner bottom of the automatic injection liquid chromatograph 1. The servo motor 402 is embedded in the upper side of the interior of the automatic injection liquid chromatograph 1. A second synchronous wheel 403 is sleeved on the output end of the servo motor 402. A synchronous belt 405 is wound between the first synchronous wheel 406 and the second synchronous wheel 403. One side of the synchronous belt 405 is fixedly connected to one side of the moving block 404. The servo motor 402 can provide stable and controllable power. The second synchronous wheel 403 at its output end drives the first synchronous wheel 406 to rotate through the synchronous belt 405, thereby causing the synchronous belt 405 to drive the moving block 404 to move along the slide bar 401. The speed and direction of the servo motor 402 are controllable, which can realize the precise positioning of the moving block 404. In conjunction with the bottom turntable of the automatic injection liquid chromatograph 1, it facilitates the sampling and injection operation.

[0034] Specifically, the working principle of this high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly is as follows: In use, the injection needle 410 is first placed between the clamping seat 407 and the locking seat 408 of the automatic injection mechanism 4. The locking seat 408 is rotated to fit the injection needle 410, and the first knob 409 is tightened to secure it. Then, the top of the push rod 414 is inserted into the moving seat 412, and the second knob 413 is tightened to secure it. The servo motor 402 is started, and its output drives the second synchronous pulley 403 to rotate. This drives the first synchronous pulley 406 through the synchronous belt 405, causing the synchronous belt 405 to drive the moving block 404 to move precisely along the slide rod 401, coordinating with the automatic injection of liquid... The bottom turntable of the auto-injection liquid chromatograph 1 is aligned with the sample vial; then, the electric telescopic rod 415 drives the moving seat 412 to descend along the optical rod 411, causing the push rod 414 to slide and extract the sample within the injection needle 410. After extraction, the servo motor 402 drives the moving block 404 to rise again, and the bottom turntable of the auto-injection liquid chromatograph 1 rotates, aligning the column inlet with the injection needle 410. The moving block 404 descends again, allowing the injection needle 410 to insert into the column inlet. The electric telescopic rod 415 pushes the push rod 414 to eject the sample, completing the injection. After injection, the user manually rotates the first knob 409 and the second knob 413 to advance the injection needle 410. The injection needle 410 is disassembled and disassembled. The cover 302 of the cleaning chamber 301 is opened, allowing the disassembled injection needle 410 to be placed into the cleaning solution in the cleaning tank 307. The ultrasonic generator 305 is activated, which provides a high-frequency electrical signal to the ultrasonic transducer 304 through a wire. The ultrasonic transducer 304 converts electrical energy into mechanical vibration, generating bubbles in the cleaning solution that impact the inner wall of the injection needle 410, the push rod 414, and the needle tip, removing residual sample. After cleaning, the waste cleaning solution is drained through the L-shaped drain pipe 303, and then pure water is poured in for repeated rinsing. After cleaning, the injection needle 410 is removed and placed inside the drying oven 201. All components of the injection needle 410 are located above the drip net 205. The hot air blower 204 is turned on, and hot air is blown into the drying oven 201 to dry the injection needle 410. The hot and humid air is discharged from the exhaust port 202. The dripping water is collected by the drip net 205 and discharged from the water outlet pipe 206. After drying is completed, the injection needle 410 is reassembled. After reassembly, the injection needle 410 is re-fixed using the clamping seat 407 and the locking seat 408 in conjunction with the first knob 409, and the push rod 414 is fixed using the second knob 413. During the detection process, multiple injection needles 410 can be used alternately to further improve the detection efficiency of the automatic injection liquid chromatograph 1.

[0035] It should be noted that all standard parts used in this application can be purchased from the market, and can be customized according to the description and drawings. The specific connection methods of each part adopt conventional methods such as bolts, rivets, and welding that are mature in the prior art. The machinery, parts and equipment adopt conventional models in the prior art. The control method is automatic control through a controller. The control circuit of the controller can be implemented by simple programming by those skilled in the art and is common knowledge in the field. Furthermore, since this application is mainly used to protect mechanical devices, this application will not explain the control method and circuit connection in detail.

Claims

1. A high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly, characterized in that, The system includes an automated liquid chromatograph (1), which has an automated injection mechanism (4) inside. A drying mechanism (2) and a cleaning mechanism (3) are respectively located on both sides of the bottom of the automated liquid chromatograph (1). The cleaning mechanism (3) includes a cleaning chamber (301), the bottom of which is connected to the bottom of the automated liquid chromatograph (1). A cleaning tank (307) is located inside the cleaning chamber (301), and a cavity (306) is formed at the bottom of the cleaning tank (307). The top of the cavity (306) is... An ultrasonic transducer (304) is installed, and a cover (302) is interference-fitted to the upper end of the cleaning box (301); the drying mechanism (2) includes a drying box (201), the bottom side of the drying box (201) is connected to the other side of the bottom of the automatic injection liquid chromatograph (1), a drip net (205) is provided at the bottom of the interior of the drying box (201), a cover plate (203) is interference-fitted to the upper end of the drying box (201), a hot air blower (204) is installed at the upper end of the cover plate (203), and the output end of the hot air blower (204) extends through the cover plate (203) into the interior of the drying box (201).

2. A high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly according to claim 1, characterized in that, An ultrasonic generator (305) is fixedly installed at the bottom of the cavity (306), and the ultrasonic generator (305) is electrically connected to the ultrasonic transducer (304) through a wire.

3. A high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly according to claim 2, characterized in that, An L-shaped drain pipe (303) is inserted into the bottom side of the cleaning tank (301), and the top end of the L-shaped drain pipe (303) is connected to the bottom side of the cleaning tank (307).

4. A high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly according to claim 1, characterized in that, The drying box (201) has several exhaust holes (202) on both sides of its upper end, and a water outlet pipe (206) is installed on the bottom side of the drying box (201).

5. A high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly according to claim 1, characterized in that, The automatic injection mechanism (4) includes a slide rod (401), which is located inside the automatic injection liquid chromatograph (1). A moving block (404) is slidably sleeved on the slide rod (401). One side of the moving block (404) is slidably connected to the inner wall of the automatic injection liquid chromatograph (1). A pair of clamping seats (407) are fixedly installed on the outer side of the moving block (404). A locking seat (408) is hinged to one end of each clamping seat (407). A first knob (409) is movably inserted into one side of the locking seat (408). One end of the first knob (409) is threadedly connected to the outer side of one end of the clamping seat (407). An injection needle (410) is inserted between the two pairs of clamping seats (407) and the locking seat (408). A push rod (414) is slidably installed inside the injection needle (410).

6. A high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly according to claim 5, characterized in that, A connecting block (416) is installed on the upper side of one side of the movable block (404). A light rod (411) is fixedly installed on the bottom side of the connecting block (416). The bottom end of the light rod (411) is connected to the top end of one of the clamping seats (407). A movable seat (412) is slidably installed on the light rod (411). An electric telescopic rod (415) is inserted into one end of the connecting block (416). The output end of the electric telescopic rod (415) is connected to the upper end of the movable seat (412). The top end of the push rod (414) extends into the interior of the movable seat (412). A second knob (413) is movably inserted into one side of the movable seat (412). One end of the second knob (413) is threadedly connected to the upper side of the push rod (414).

7. A high-performance liquid chromatograph equipped with an automatic injection needle cleaning assembly according to claim 1, characterized in that, The automatic injection mechanism (4) further includes a servo motor (402) and a first synchronous wheel (406). The central shaft of one side of the first synchronous wheel (406) is rotatably connected to the inner bottom side of the automatic injection liquid chromatograph (1). The servo motor (402) is embedded in the upper side of the inside of the automatic injection liquid chromatograph (1). The output end of the servo motor (402) is fitted with a second synchronous wheel (403). A synchronous belt (405) is wound between the first synchronous wheel (406) and the second synchronous wheel (403). One side of the synchronous belt (405) is fixedly connected to one side of the moving block (404).

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