A device for simultaneous administration of drugs to the skin of a domestic rabbit

Abstract

The utility model relates to the field of animal testing apparatus, disclose rabbit skin simultaneous dosing restraint device, including movable table body, rabbit body restraint box and platform cover. The movable table body rear end is equipped with recess, and the recess middle part is opened one drainage hole. Rabbit body restraint box is installed on the table body upper surface, and there is a semicircular recess in the front baffle upper side along the central axis, and the recess has semicircular buckle, through the fixed pet rabbit neck, further restraint pet rabbit, the restraint box upper cover is the movable cover, is used in giving the test object after necessary fixed animal, the restraint box rear baffle lower side is equipped with the aperture, is used for discharging animal excrement. The platform cover includes cover body, shadowless lamp and exhaust system. The cover body can move up and down, and the shadowless lamp is convenient for giving the test object and observing the animal state together, and a plurality of air inlets are arranged around the lower side, and the inside and outside of the cover body can be rapidly exchanged. The rabbit skin simultaneous dosing restraint device is especially suitable for the situation that the number of experimental animals is more and / or the test object needs to be given repeatedly for many times in a short time.

Description

Technical Field

[0001] This utility model relates to the field of experimental equipment technology, and belongs to the field of testing pharmacological activity and safety evaluation (i.e. toxicity) of external test substances (including drugs, medical devices, cosmetics, health products, etc.) on animal skin. Background Technology

[0002] Before being marketed, pharmaceuticals, cosmetics, medical aesthetic products, and health supplements mostly require corresponding pharmacological and toxicological tests. Laboratory animals play a crucial role in evaluating the efficacy and safety of these products during these tests. When the skin is used as the target or delivery medium for test substances, transdermal administration to animals is often an essential method in experimental research. Currently, rabbits are a popular choice for transdermal drug delivery due to their thin skin, ease of absorption of test substances, and sensitivity to stimuli. They also offer advantages such as moderate size, docile temperament, abundant availability, low cost, and ease of training and handling. In experimental research, to obtain accurate and reliable data that can guide clinical practice, a relatively large number of animals are typically used in each group. Furthermore, animal experiments generally administer the test substance based on its clinical frequency and number of administrations. Transdermal administration is usually characterized by repeated, multiple uses, resulting in a relatively high frequency and number of administrations per animal per day. If the above situations are encountered in experiments, on the one hand, repeatedly grasping, administering medication, and restraining the animals consumes a lot of manpower, and on the other hand, it also affects the efficiency of the experiment. Furthermore, repeated grasping operations can easily cause animal agitation, affecting the accuracy of the experimental results. Therefore, the rabbit skin-administered medication and restraint device of the present invention can solve the above problems. Utility Model Content

[0003] The purpose of this invention is to provide a restraint device for simultaneous skin administration of drugs to rabbits, which can reduce human intervention and improve the efficiency of drug administration and the accuracy and reliability of experimental results.

[0004] To achieve the above objectives, this utility model provides the following technical solution: a rabbit skin-administering restraint device, comprising a movable platform, a rabbit restraint box, and a platform cover. The movable platform has a certain angle at the front and rear, and a groove of a certain width is provided at the rear end of the platform, with a drainage hole with a filter screen in the middle of the groove. The rabbit restraint box is installed on the upper surface of the platform; a semi-circular groove is provided along the central axis above the front baffle of the rabbit restraint box, and a corresponding semi-circular buckle that can move freely up and down is installed simultaneously; the upper cover of the restraint box is a hollow movable cover; an opening is provided below the rear baffle of the restraint box. The platform cover includes a cover body, a shadowless lamp, and a ventilation system. The front and rear covers of the cover body can move up and down; multiple small air inlets are provided around the bottom of the cover body.

[0005] Preferably, the mobile platform, rabbit restraint box, and platform cover should be made of lightweight and strong materials (such as aluminum alloy, magnesium alloy, etc.) to facilitate handling and movement.

[0006] Preferably, the front and rear of the table should have an inclination angle of at least 10º to 15º.

[0007] Preferably, the movable platform support legs are equipped with rollers with fixing devices.

[0008] Preferably, the groove is slightly higher on both sides and lower in the middle, and a drain pipe is installed below the middle drain hole.

[0009] Preferably, the movable platform is provided with a hinged connection device on both sides that can connect the same fixed platform in series.

[0010] Preferably, five rabbit restraint boxes can be installed on the platform, and they can be freely assembled and disassembled.

[0011] Preferably, both the circular groove and the semi-circular buckle are covered with a layer of soft material to avoid injury to the rabbit's neck during restraint.

[0012] Preferably, the upper cover is semi-raised and hollow, and is connected to the fixed baffles on both sides in a certain way. When needed, the upper cover is closed, and together with the circular groove and semi-circular buckle, it restrains the experimental animal.

[0013] Preferably, the table cover is securely connected to the table surface and can be freely disassembled.

[0014] Preferably, the shadowless lamp (such as an LED lamp) installed at the top inside the stage cover is a cold light source to facilitate operation by laboratory personnel and observation of animals.

[0015] Preferably, the airflow of the exhaust system and the light intensity of the shadowless lamp can be freely adjusted according to the nature and requirements of the experiment. The adjustment methods include either a knob fixed on the device or a remote control.

[0016] Preferably, both the shadowless lamp and the ventilation system can be powered by wired or battery power.

[0017] Preferably, all four sides of the platform cover are made of a safe transparent material (such as plexiglass) to facilitate observation.

[0018] Preferably, the sliding platform cover should be equipped with a locking device.

[0019] Preferably, the device has an arc-shaped design at each corner to facilitate cleaning and wiping after use.

[0020] The beneficial effects of this utility model are as follows: The rabbit skin-administered drug restraint device, by placing the experimental rabbit in multiple rabbit restraint boxes on a mobile platform in a semi-restrained manner, avoids the agitation caused by repeated grasping and restraint operations when the test substance needs to be administered to the skin multiple times, which would affect the accuracy of the experimental results; at the same time, when the number of animals is set in the experiment, it can also improve work efficiency and reduce manual labor.

[0021] The above description is only an overview of the technical solution of this utility model. In order to better understand the technical means of this utility model and to implement it in accordance with the contents of the specification, the preferred embodiments of this utility model are described in detail below with reference to the accompanying drawings. Attached Figure Description

[0022] Figure 1 is a schematic diagram of the movable platform.

[0023] Figure 2 is a schematic diagram of the rabbit restraint box structure.

[0024] Figure 3 is a schematic diagram of the platform cover structure.

[0025] The figure includes a movable platform (100), a rabbit restraint box (200), a platform cover (300), a platform surface (101), a groove of a certain width (102), a drainage hole (103), a drainage pipe (104), a twisting device (105), a front baffle (201), a semi-circular groove (202), a semi-circular buckle (203), a top cover (204), a rear baffle (205), an opening (206), a cover body (301), a shadowless lamp (302), an exhaust system (303), front and rear covers (304), and an air inlet hole (305). Detailed Implementation

[0026] The specific embodiments of this utility model will be described in further detail below with reference to the accompanying drawings and examples. The following examples are used to illustrate this utility model, but are not intended to limit its scope.

[0027] As shown in Figures 1-3, this utility model relates to a rabbit skin-administered restraint device, comprising: a movable platform (100), a rabbit restraint box (200), and a platform cover (300). The movable platform (100) has a platform surface (101) with a certain angle at the front and rear. The rear end of the platform surface (101) is provided with a groove (102) of a certain width, and a drainage hole (103) with a filter screen is opened in the middle of the groove (102). The rabbit restraint box (200) is installed on the upper surface of the platform (100). The front baffle (201) of the rabbit restraint box (200) has a semi-circular groove (202) along the central axis above it, and a semi-circular buckle (203) that can move freely up and down is installed at the same time, corresponding to the groove (202). The upper cover plate (204) of the restraint box is a hollow movable cover plate. An opening (206) is opened below the rear baffle plate (205) of the restraint box. The table cover (300) includes a cover body (301), a shadowless lamp (302), and an exhaust system (303). The front and rear covers (304) of the cover body (301) can move up and down; multiple small air inlets (305) are provided around the bottom of the cover body (301).

[0028] In the above embodiments, the support of the mobile platform (100) is made of magnesium alloy, and the platform panel rabbit body restraint box (200) and platform cover (300) should be made of lightweight and strong materials as much as possible to facilitate handling and movement.

[0029] In the above embodiment, the tabletop (101) is tilted 10º forward and backward.

[0030] In the above embodiment, the support legs of the movable platform (100) are provided with rollers with fixing devices.

[0031] In the above embodiment, the groove (102) of a certain width is slightly higher on both sides and lower in the middle, and a drain pipe (104) is installed below the middle drain hole (103).

[0032] In the above embodiment, the movable platform (100) is provided with a hinge device (105) on both sides that can connect the same fixed platform in series.

[0033] In the above embodiment, five rabbit restraint boxes (200) can be installed on the table (101) and can be freely assembled and disassembled.

[0034] In the above embodiments, both the circular groove (202) and the semi-circular buckle (203) are covered with a layer of soft material to avoid damage to the rabbit's neck during restraint.

[0035] In the above embodiment, the upper cover plate (204) and the fixed baffles on both sides are connected in a certain way to restrain the experimental animals.

[0036] In the above embodiments, the table cover (300) and the table surface (101) are firmly connected and can be freely disassembled.

[0037] In the above embodiment, the shadowless lamp (302) installed at the top inside the stage cover (300) is a cold light source to facilitate operation by experimental personnel and observation of animals.

[0038] In the above embodiments, the wind force of the exhaust system (303) and the light intensity of the shadowless lamp (302) can be freely adjusted according to the nature and requirements of the experiment. The adjustment methods include fixed or remote control.

[0039] In the above embodiments, both the shadowless lamp (302) and the ventilation system (303) can be powered by wired or battery packs.

[0040] In the above embodiment, all four sides of the stage cover (300) are made of safe transparent material for easy observation.

[0041] In the above embodiments, the sliding platform cover (300) should be equipped with a locking device.

[0042] In the above embodiments, each corner of the device is designed with an arc shape to facilitate cleaning and wiping after use.

[0043] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0044] The above embodiments only illustrate several implementation methods of this utility model, and their descriptions are relatively specific and detailed, but they should not be construed as limiting the scope of the utility model patent. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this utility model, and these all fall within the protection scope of this utility model. Therefore, the protection scope of this utility model patent should be determined by the appended claims.

Claims

1. A device for simultaneously administering medication and restraining rabbits through the skin, characterized in that, include: The mobile platform (100), the rabbit restraint box (200), and the platform cover (300) are as follows: the front and rear of the platform (101) of the mobile platform (100) are inclined at a certain angle, and the rear end of the platform (101) is provided with a groove (102) of a certain width, and a drainage hole (103) with a filter screen is opened in the middle of the groove (102); the rabbit restraint box (200) is installed on the upper surface of the platform (100); the front baffle (201) of the rabbit restraint box (200) has a semi-circular groove (202) along the central axis above it, and a semi-circular buckle (203) that can move freely up and down is installed at the same time, corresponding to the semi-circular groove (202); the upper cover plate (204) of the restraint box is a hollow movable cover plate; an opening (206) is opened below the rear baffle (205) of the restraint box; the platform cover (300) includes a cover body (301). ), shadowless lamp (302) and exhaust system (303); the front and rear covers (304) of the cover (301) can move up and down; multiple air inlets (305) are provided around the bottom of the cover (301).

2. The rabbit skin-administered drug restraint device according to claim 1, characterized in that: The movable platform (100), rabbit restraint box (200), and platform cover (300) should be made of lightweight and strong materials to facilitate handling and movement.

3. The rabbit skin-administered drug restraint device according to claim 1, characterized in that: The tabletop (101) should have a tilt angle of at least 2º at the front and back.

4. The rabbit skin-administered drug restraint device according to claim 1, characterized in that: The mobile platform (100) has casters with locking devices on its support legs.

5. The rabbit skin-administered drug restraint device according to claim 1, characterized in that: The groove (102) of a certain width is slightly higher on both sides and lower in the middle, and a drain pipe (104) is installed below the middle drain hole (103).

6. The rabbit skin-administered drug restraint device according to claim 1, characterized in that: The movable platform (100) is provided with a connecting device (105) on both sides that can connect the same Baoding platform in series.

7. The rabbit skin-administered drug restraint device according to claim 1, characterized in that: Two to five rabbit restraint boxes (200) can be installed on the table (101), and they can be freely assembled and disassembled.

8. The rabbit skin-administered drug restraint device according to claim 1, characterized in that: The circular groove (202) and the semi-circular buckle (203) are both covered with a layer of soft material to avoid damage to the rabbit's neck during restraint.

9. The rabbit skin-administered drug restraint device according to claim 1, characterized in that: The upper cover plate (204) is connected to the fixed baffles on both sides in a certain way to restrain the experimental animals.

10. The rabbit skin-administered drug restraint device according to claim 1, characterized in that: The table cover (300) and the table surface (101) are firmly connected and can be freely disassembled.

11. The rabbit skin-administered drug restraint device according to claim 1, characterized in that: The shadowless lamp (302) installed at the top inside the stage cover (300) is a cold light source to facilitate operation by experimental personnel and observation of animals.

12. The rabbit skin-administered drug restraint device according to claim 1 or 11, characterized in that: The wind force of the exhaust system (303) and the light intensity of the shadowless lamp (302) can be freely adjusted according to the nature and requirements of the experiment. The adjustment methods include fixed or remote control.

13. The rabbit skin-administered drug restraint device according to claim 12, characterized in that: The shadowless lamp (302) and the ventilation system (303) can both be powered by wired or battery packs.

14. The rabbit skin-administered drug restraint device according to claim 1, characterized in that: The four sides of the stage cover (300) are made of safe transparent material for easy observation.

15. The rabbit skin-administered drug restraint device according to claim 1, characterized in that: The platform cover (300) should be equipped with a locking device.

16. The rabbit skin-administered drug restraint device according to claim 1, characterized in that: The device features an arc-shaped design at each corner to facilitate cleaning and wiping after use.

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