Three-dimensional incubation function shaking table

Abstract

The utility model discloses a three -dimensional shaking table with incubation function, including base, the tray of support on the base of shaking and the tray top's tray cover, be provided with flexible liquid storage cavity on the tray cover, the liquid is filled in the flexible liquid storage cavity, the flexible liquid storage cavity has the flexible cavity wall corresponding with the tray inboard bottom, be provided with the temperature control device of control liquid temperature in the flexible liquid storage cavity on the tray cover, when the tray cover buckling on the tray, the flexible cavity wall and the heat conduction contact of the article that is shaken in the tray. The utility model's shaking table upper inboard adopts the water bag water heating, and the soft top water bag makes test sample and heating device better adhere, guarantees the incubation effect. Compared with traditional water bath, more safe and neat, the water bath design of water separation, prevents the pollution caused by sample overflow when incubating, more in line with the biological safety requirement, and the equipment is simple, convenient to move, low in cost, and the grass-roots medical institutions promote the use.

Description

Technical Field

[0001] This utility model relates to the field of biomedical equipment technology, and in particular to a three-dimensional shaker with incubation function. Background Technology

[0002] Clinical trials often require constant temperature incubation of specimens and experimental products. For example, certain diseases (such as mycoplasma pneumonia, lymphoma, and cold agglutinin disease) can cause a significant increase in the titer of cold agglutinins in patients. Test samples must be strictly pre-warmed at 37°C to eliminate cold agglutination interference, prevent agglutination caused by excessively low operating temperature, and ensure the accuracy of test results such as routine blood tests.

[0003] Currently, many laboratories handle such samples by using traditional water bath heating. However, once the sample is removed from the water bath environment for thorough mixing or other operations, it cools down and causes the sample to re-cold and agglomerate, especially when using high-titer cold antibodies or when the ambient temperature is low.

[0004] Since such specimens are generally not produced in large quantities at the same time in clinical practice, from the perspective of solving practical clinical problems, it is sufficient to meet clinical needs by simultaneously incubating and shaking a small number of specimens at a constant temperature.

[0005] Currently available 3D shakers do not have a constant temperature incubation function. In experiments, the shaker needs to be placed in a constant temperature chamber or a special constant temperature chamber with a shaker is required, which is costly, inconvenient to move, and inconvenient to operate.

[0006] Therefore, a new type of shaker with constant temperature incubation function is needed in clinical trials. Utility Model Content

[0007] To solve at least one of the above-mentioned technical problems, this utility model provides a three-dimensional shaker with incubation function, which can incubate specimens at a constant temperature while shaking. It has a simple structure and is easy to use.

[0008] The technical solution adopted in this utility model is to design a three-dimensional shaker with incubation function, including a base, a shaking tray supported on the base, and a cover located above the tray. The cover is provided with a flexible liquid storage cavity, which is filled with liquid. The flexible liquid storage cavity has a flexible cavity wall corresponding to the bottom inner side of the tray. The cover is provided with a temperature control device to control the temperature of the liquid in the flexible liquid storage cavity. When the cover is fastened to the tray, the flexible cavity wall is in thermally conductive contact with the shaken items in the tray.

[0009] In some embodiments, the tray is also equipped with a temperature control device.

[0010] In some embodiments, the bottom inner side of the tray is provided with anti-slip protrusions.

[0011] In some embodiments, the flexible liquid storage cavity is divided into multiple non-interconnected sub-liquid storage cavities.

[0012] In some embodiments, the inner side of the disc cover has an upwardly recessed cover cavity, and the port of the cover cavity is sealed by a flexible membrane to form the flexible liquid storage cavity.

[0013] In some embodiments, the flexible liquid storage chamber is connected to a liquid volume control device, which controls the amount of liquid in the flexible liquid storage chamber.

[0014] In some embodiments, the flexible liquid storage chamber includes multiple independent sub-liquid storage chambers.

[0015] In some embodiments, the sub-liquid storage cavities are arrayed on the covering surface.

[0016] In some embodiments, each of the sub-storage chambers is connected to the liquid volume control device via an independent control valve, so that the liquid volume of each sub-storage chamber can be adjusted independently.

[0017] In some embodiments, the liquid volume control device includes a liquid storage tank and a liquid pump connecting the liquid storage tank and the flexible liquid storage chamber.

[0018] Compared with the prior art, the present invention has the following beneficial effects:

[0019] The upper inner layer of the shaker in this invention uses a water bag for water-insulated heating. The soft-top water bag allows the test sample to better fit with the heating device and increases the contact area, ensuring effective incubation. The lower part of the shaker uses a metal bath for heating, and the rigid bottom with horizontal grooves ensures that the sample container is better fixed to the bottom plane, preventing slippage and maintaining a good shaking effect. The upper and lower surfaces of the sample fixing device use a combination of soft and hard materials, which can increase the variety of compatible sample containers and expand the product's applicability.

[0020] Compared to traditional water baths, this method is safer and cleaner. The water-proof design prevents sample spillage and contamination during incubation, better meeting biosafety requirements. Compared to large incubators with shakers, this equipment is simpler, easier to move, and lower in cost, making it easier for primary healthcare institutions to adopt. Attached Figure Description

[0021] The present invention will now be described in detail with reference to specific embodiments and accompanying drawings. To illustrate the details and facilitate understanding of its principles, the drawings are not necessarily to scale, and similar reference numerals may describe similar components in different views. The accompanying drawings generally illustrate the embodiments discussed herein by way of example and not limitation. Wherein:

[0022] Figure 1This is a cross-sectional schematic diagram of the three-dimensional shaker in Embodiment 1 when it is open.

[0023] Figure 2 This is a cross-sectional schematic diagram of the three-dimensional shaking table during engagement in Embodiment 1.

[0024] Figure 3 This is a schematic diagram showing that the flexible liquid storage chamber is divided into multiple non-interconnected sub-liquid storage chambers.

[0025] Figure 4 This is a diagram of the bottom of the tray.

[0026] Figure 5 This is a cross-sectional schematic diagram of the three-dimensional shaker in Embodiment 2 when it is open.

[0027] Figure 6 Yes, this is a cross-sectional diagram of the three-dimensional shaking table during engagement.

[0028] In the diagram, 1. Base; 2. Tray; 3. Cover; 4. Specimen; 5. Flexible liquid storage chamber; 6. Flexible chamber wall; 7. Electric heater; 8. Flexible diaphragm; 9. Sub-liquid storage chamber; 10. Liquid storage tank; 11. Liquid pump; 12. Small bag; 13. Control valve; 14. Anti-slip protrusion. Detailed Implementation

[0029] The following are specific embodiments of this utility model, and the technical solution of this utility model will be further described with reference to the accompanying drawings. However, this utility model is not limited to these embodiments, and the following embodiments do not limit the utility model involved in the claims. In addition, all combinations of features described in the embodiments are not necessarily necessary for the solution of the utility model.

[0030] The principle and structure of this utility model will be described in detail below with reference to the accompanying drawings and embodiments.

[0031] Example 1

[0032] like Figure 1 , 2 As shown, a three-dimensional shaker with incubation function is similar to a regular three-dimensional shaker, including a base 1, a shaking tray 2 supported on the base 1, and a cover 3 located above the tray 2. In use, the object to be shaken (e.g., a biological specimen 4) is placed in the tray 2, the cover 3 is closed, and the power device on the base 1 can shake the tray 2, thereby shaking the object.

[0033] Unlike existing technologies, this embodiment features a flexible liquid storage cavity 5 on the cover 3, filled with liquid such as water. The flexible liquid storage cavity 5 has a flexible cavity wall 6 corresponding to the bottom inner side of the tray 2. The cover 3 is equipped with a temperature control device to regulate the temperature of the liquid within the flexible liquid storage cavity 5. When the cover 3 is fastened to the tray 2, the flexible cavity wall 6 makes thermal contact with the biological specimen 4 within the tray 2, thereby allowing the liquid in the flexible liquid storage cavity 5 to exchange heat with the biological specimen 4, maintaining the biological specimen 4 at a suitable temperature.

[0034] The temperature control device is an electric heater 7 mounted on the tray cover 3. The electric heater 7 can be, for example, a resistance heating wire mounted on the tray cover 3 or insulated within the flexible liquid storage chamber 5, similar to the principle of a kettle, thereby heating the liquid within the flexible liquid storage chamber 5 to maintain a suitable temperature for the constant-temperature incubation of the biological specimen 4. A temperature control device can also be mounted on the tray 2, such as a resistance heater mounted on the bottom or side wall of the tray 2. Of course, the temperature control device also includes temperature sensors to achieve closed-loop temperature control, which is a conventional technology in the field of temperature control and will not be elaborated upon here. The temperature control device is not limited to heating devices; it can also include cooling devices, such as semiconductor cooling chips, to cool the specimen 4, enabling rapid and accurate temperature acquisition, or to allow the specimen 4 to be shaken at a suitable low temperature.

[0035] The flexible liquid storage chamber 5 is equivalent to a bag containing liquid fixed inside the cover 3. The bag can be a plastic bag, rubber bag, silicone bag, or other bag with good strength and thermal conductivity. The bag does not need to be filled too full so that the bag has good flexibility and deformation ability. The upper part of the bag is fixedly connected to the inside of the cover 3, and the lower part hangs down naturally under the gravity of the liquid in the chamber. Because the bag has good flexibility, when the cover 3 is closed, the hanging part can adapt to the size and shape of the container (e.g., test tube) of the specimen 4 when it comes into contact with the specimen 4 in the tray 2, so that it can fit better with the container of the specimen 4. This is not only beneficial for heat conduction but also for squeezing and fixing the specimen 4.

[0036] like Figure 4 As shown, the bottom inner side of the tray 2 is provided with anti-slip protrusions 14 to prevent the specimen 4 from moving. The specimen 4 is squeezed between the bag and the anti-slip protrusions 14, which makes the specimen 4 more secure. Since the liquid and the specimen 4 are separated by the bag, it is safer and cleaner than traditional water baths. The water-proof water bath design prevents the sample from spilling and causing contamination during incubation, which is more in line with biosafety requirements.

[0037] Furthermore, such as Figure 3As shown, the flexible liquid storage chamber 5 is divided into multiple non-interconnected sub-liquid storage chambers 9. In this embodiment, the flexible liquid storage chamber 5 is divided into matrix sub-liquid storage chambers 9 by longitudinal and transverse flexible diaphragms 8 inside the bag. In this way, even if part of the bag is damaged, only the liquid in the corresponding sub-liquid storage chamber 9 will leak, while the liquid in other sub-liquid storage chambers 9 will not leak.

[0038] Typically, the inner side of the cover 3 has an upwardly recessed cover cavity. Therefore, simply, this cover cavity can also be used as part of the liquid storage cavity. A flexible membrane can be sealed at the port of the cover cavity to form a flexible liquid storage cavity 5. When the cover 3 is fastened, the flexible membrane covering the port of the cover cavity serves as the flexible cavity wall 6 that contacts the specimen 4 in the tray 2.

[0039] Example 2

[0040] like Figure 5 , 6 As shown, the flexible liquid storage chamber 5 is further connected to a liquid volume control device, which controls the amount of liquid in the flexible liquid storage chamber 5. The liquid volume control device includes a liquid storage tank 10 located at the base 1 and a liquid pump 11 connecting the liquid storage tank 10 and the flexible liquid storage chamber 5. The liquid pump 11 transfers liquid between the liquid storage tank 10 and the flexible liquid storage chamber 5, thereby adjusting the amount of liquid in the flexible liquid storage chamber 5 and controlling its size to accommodate the number of specimens 4 in the tray 2. If there are many specimens 4, the amount of liquid in the flexible liquid storage chamber 5 can be reduced to provide more space for the specimens 4. Alternatively, before the tray cover 3 is closed, the flexible liquid storage chamber 5 can be kept with a small amount of liquid. After the tray cover 3 is closed, liquid is pumped into the flexible liquid storage chamber 5 to enlarge it and ensure full contact with the specimens 4, thus creating pressure in the flexible liquid storage chamber 5 to hold the specimens 4 in place. In this case, a temperature-controlled heater can be installed inside the liquid storage tank 10.

[0041] Furthermore, the flexible liquid storage chamber 5 in this embodiment is composed of multiple independent sub-liquid storage chambers, each of which is an independent small bag 12, thus improving the overall adaptability and deformation capability. The sub-liquid storage chambers are arrayed on the covering surface of the tray cover 3, and each sub-liquid storage chamber is connected to the liquid volume control device through an independent control valve 13, allowing the liquid volume of each sub-liquid storage chamber to be adjusted independently. By opening the control valve 13, the corresponding sub-liquid storage chamber is connected to the liquid storage tank 10, thereby allowing the liquid pump 11 to control the water volume in the corresponding sub-liquid storage chamber. Since the sub-liquid storage chambers are independent small bags 12, the size of the liquid storage chambers in different areas of the covering surface can be controlled to better adapt to the shape of the object in the tray 2. For example, when the specimen 4 is in the middle position, the liquid volume of the sub-liquid storage chamber corresponding to the central area can be reduced, while the liquid volume of the sub-liquid storage chambers in the surrounding areas can be increased, thus allowing the flexible liquid storage chamber 5 to fit better with the specimen 4 and facilitating better fixation of the specimen 4.

[0042] The specific embodiments described herein are merely illustrative examples illustrating the spirit of this utility model. Those skilled in the art to which this utility model pertains may make various modifications or additions to the described specific embodiments or use similar methods to replace them, without departing from the spirit of this utility model or exceeding the scope defined by the appended claims.

Claims

1. A three-dimensional shaker with incubation function, comprising a base, a rocking tray supported on the base, and a tray cover located above the tray, characterized in that, The tray cover is provided with a flexible liquid storage cavity, which is filled with liquid. The flexible liquid storage cavity has a flexible cavity wall corresponding to the bottom inner side of the tray. The tray cover is provided with a temperature control device to control the temperature of the liquid in the flexible liquid storage cavity. When the tray cover is fastened to the tray, the flexible cavity wall is in thermal contact with the shaken items in the tray.

2. The three-dimensional shaker with incubation function according to claim 1, characterized in that, The tray is also equipped with a temperature control device.

3. The three-dimensional shaker with incubation function according to claim 1, characterized in that, The bottom inner side of the tray is provided with anti-slip protrusions.

4. The three-dimensional shaker with incubation function according to claim 1, characterized in that, The flexible liquid storage chamber is divided into multiple non-interconnected sub-liquid storage chambers.

5. The three-dimensional shaker with incubation function according to claim 1, characterized in that, The inner side of the cover has an upwardly recessed cover cavity, and the port of the cover cavity is sealed by a flexible membrane to form the flexible liquid storage cavity.

6. The three-dimensional shaker with incubation function according to claim 1, characterized in that, The flexible liquid storage chamber is connected to a liquid volume control device, which controls the amount of liquid in the flexible liquid storage chamber.

7. The three-dimensional shaker with incubation function according to claim 6, characterized in that, The flexible liquid storage chamber includes multiple independent sub-liquid storage chambers.

8. The three-dimensional shaker with incubation function according to claim 7, characterized in that, The sub-liquid storage chambers are arrayed on the covering surface.

9. The three-dimensional shaker with incubation function according to claim 7, characterized in that, Each of the sub-storage chambers is connected to the liquid volume control device via an independent control valve, allowing the liquid volume of each sub-storage chamber to be adjusted independently.

10. The three-dimensional shaker with incubation function according to claim 6, characterized in that, The liquid volume control device includes a liquid storage tank and a liquid pump connecting the liquid storage tank and the flexible liquid storage chamber.

Images