Frozen tissue processing device
Patent Information
- Application Number
- CN202521399053.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-07-04
- Publication Date
- 2026-08-18
- Estimated Expiration
- 2035-07-04
AI Technical Summary
[0004]然而,病理科术中冰冻诊断后剩余标本处理流程繁琐、人工操作效率低,难以满足高工作量需求,甚至还会导致标本固定不及时,可能影响后续病理检测准确性
[0017] (1) Compared with the dyeing and separation steps in related technologies that rely on manual labor, this application realizes the whole process of "thawing-dyeing-separation-recycling" through the synergistic effect of heating components, spraying devices, push plates and recycling devices, which improves the degree of automation and reduces the intensity of manual operation;
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Figure CN224650992U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of specimen preparation auxiliary devices, and in particular to frozen tissue processing devices. Background Technology
[0002] Intraoperative frozen section is a rapid diagnostic technique in pathology. During surgery, freshly removed tissue samples are rapidly frozen and prepared into sections for pathologists to observe under a microscope, helping surgeons quickly determine the nature of lesions during the operation.
[0003] In related techniques, after intraoperative frozen section diagnosis in the pathology department, the operator needs to first stain the cut surface of the frozen section with hematoxylin, wait for the frozen tissue embedding gel to thaw at room temperature, and then put it into a specimen bag filled with fixative such as formalin for preservation and subsequent pathological testing.
[0004] However, the process of handling the remaining specimens after intraoperative frozen section diagnosis in pathology is cumbersome and inefficient due to low manual operation, making it difficult to meet the demands of high workloads. It may even lead to untimely specimen fixation, which may affect the accuracy of subsequent pathological tests. Utility Model Content
[0005] The present invention aims to at least solve one of the technical problems existing in the prior art. Therefore, one objective of the present invention is to provide a frozen tissue processing device that improves the processing efficiency of frozen tissue and reduces the workload of medical personnel.
[0006] This invention provides a frozen tissue processing device, comprising a base, a specimen tray support plate, a heating assembly, a spraying device, a recovery device, and a pusher plate. One end of the specimen tray support plate is rotatably mounted on the base to form a rotating connection end, and the other end extends away from the rotating connection end to form an extension end. The heating assembly is embedded in the specimen tray support plate and is used to heat and thaw the specimen tray on the support plate. The spraying device includes a nozzle located above the specimen tray support plate for spraying staining solution. The recovery device is located below the specimen tray support plate and contains a first cavity and a second cavity. The top of the recovery device has a first inlet communicating with the first cavity and a second cavity communicating with the second cavity. The second inlet, the first inlet and the second inlet are configured to be arranged sequentially in a direction away from the rotating connection end, the first cavity is used to retrieve the specimen tray, and the second cavity is used to retrieve bagged specimens; the specimen tray support plate has a downward tilting position and a horizontal position: in the downward tilting position, the extension end is located above the first inlet; in the horizontal position, the extension end is located above the second inlet; a push plate is provided on the base and is used to push the specimen on the specimen tray support plate so that the specimen is disengaged from the specimen tray support plate to the side away from the rotating connection end.
[0007] In some embodiments, the frozen tissue processing apparatus further includes an adsorption component embedded in the specimen holder support plate; the adsorption component is configured to adsorb the specimen holder when the specimen holder support plate is in the horizontal position and to release the adsorption on the specimen holder when the specimen holder support plate is in the downward tilt position.
[0008] In some embodiments, the adsorption component is configured as a vacuum adsorption device or an adjustable magnetic adsorption device.
[0009] In some embodiments, the recycling device is further provided with a disinfectant inlet and a disinfectant outlet that communicate with the first cavity.
[0010] In some embodiments, the cavity wall of the first cavity is provided with a heating wire.
[0011] In some embodiments, the frozen tissue processing apparatus further includes a guide device disposed between the specimen holder support plate and the second cavity; the guide device has an inclined guide surface, one end of which is configured to be located directly below an extension end of the specimen holder support plate when the specimen holder support plate is in a horizontal position, the inclined guide surface extending downward along a side away from the rotatable connection end into the second cavity; the guide device defines at least a portion of the second inlet.
[0012] In some embodiments, one end of the inclined guide surface is connected to an upwardly extending transverse baffle and a drainage baffle connected to both ends of the transverse baffle; the two drainage baffles are perpendicular to the inclined guide surface and extend approximately along the inclined direction of the inclined guide surface, and the two drainage baffles gradually approach each other in the extending direction; a fixed liquid inlet is provided on the transverse baffle.
[0013] In some embodiments, the frozen tissue processing apparatus further includes a fixative supply device; the fixative supply device includes a fixative storage tank, a fixative supply pump, and a fixative supply pipe; the fixative supply pipe is connected between the fixative storage tank and the fixative inlet, and the fixative supply pump is connected to the fixative supply pipe and is used to drive the fixative from the fixative storage tank to the fixative inlet on the transverse baffle.
[0014] In some embodiments, the frozen tissue processing apparatus further includes a pusher plate driving device; the pusher plate driving device is used to drive the pusher plate to move away from the rotating connection end.
[0015] In some embodiments, the frozen tissue processing apparatus further includes a telescopic drive rod; one end of the telescopic drive rod is hinged to the lower surface of the specimen support plate, and the other end of the telescopic drive rod is hinged to the base, the telescopic drive rod being used to drive the specimen support plate to rotate during telescopic movement.
[0016] As can be seen from the technical solution, the embodiments provided by this utility model have the following advantages:
[0017] (1) Compared with the dyeing and separation steps in related technologies that rely on manual labor, this application realizes the whole process of "thawing-dyeing-separation-recycling" through the synergistic effect of heating components, spraying devices, push plates and recycling devices, which improves the degree of automation and reduces the intensity of manual operation;
[0018] (2) Heating and thawing and spray dyeing can be carried out simultaneously, reducing waiting time and improving efficiency;
[0019] (3) Parameters such as heating time and staining solution spray volume can be controlled more precisely, reducing the instability of specimen status caused by differences in manual operation. Attached Figure Description
[0020] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0021] Figure 1 This is a cross-sectional view of a frozen tissue processing apparatus according to an embodiment of the present invention;
[0022] Figure 2 This is a schematic diagram of the overall structure of the frozen tissue processing device according to an embodiment of the present utility model;
[0023] Figure 3 This is a schematic diagram of the structure of the first cavity according to an embodiment of the present utility model.
[0024] Figure label:
[0025] Frozen tissue processing device 100, specimen tray 200, disinfectant storage tank 300;
[0026] Base 1;
[0027] Specimen support plate 2, rotating connection end 21, extension end 22;
[0028] Spraying device 3, nozzle 31, dyeing agent inlet pipe 32, dyeing agent supply device 33;
[0029] Recovery device 4, first chamber 41, first inlet 411, disinfectant inlet 412, disinfectant outlet 413, heating wire 414, second chamber 42, second inlet 421;
[0030] Push plate 5;
[0031] Guide device 6, inclined guide surface 61, transverse baffle 62, fixed liquid inlet 621, and drainage baffle 63;
[0032] Fixative supply device 7;
[0033] Push plate drive device 8;
[0034] Telescopic drive rod 9. Detailed Implementation
[0035] The embodiments of this utility model are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this utility model, and should not be construed as limiting this utility model.
[0036] In the description of this utility model, it should be understood that the terms "center," "longitudinal," "transverse," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," and "circumferential," etc., indicating the orientation or positional relationship shown in the accompanying drawings, are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, features defined with "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this utility model, unless otherwise stated, "a plurality of" means two or more.
[0037] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.
[0038] Intraoperative frozen section is a rapid diagnostic technique in pathology. During surgery, freshly removed tissue samples are rapidly frozen to create sections for pathologists to observe under a microscope. This helps surgeons quickly determine the nature of the lesion (such as benign or malignant, and whether the surgical margins are clean) during surgery, and pathological diagnosis results are usually available within 30 minutes.
[0039] Frozen sections refer to the technique of rapidly freezing and solidifying fresh tissue in a low-temperature environment (below -20°C), then cutting it into thin sections (approximately 4-10 micrometers thick) using a cryostat, and finally staining it to prepare microscopic observation samples.
[0040] During the freezing process, a frozen specimen holder is needed to fix and support the tissue. The frozen specimen holder is usually a metal circular tray with a diameter of 2 cm. After the fresh tissue is placed on the specimen holder, a cryoemulation medium (such as OCT) is injected. After freezing, it forms a regular-shaped hard block, which is convenient for the cryostat to hold and section.
[0041] In related techniques, after intraoperative freezing, the tissue still needs to be manually processed, as follows:
[0042] 1. Staining: Apply hematoxylin staining solution manually to the frozen tissue section for staining;
[0043] 2. Tissue separation: The embedding gel melts naturally at room temperature, allowing the tissue to separate from the specimen holder;
[0044] 3. Sealing and fixation: Manually place the tissue into a specimen bag and infuse formalin.
[0045] 4. Specimen tray processing: Manual cleaning, disinfection, and drying of specimen trays.
[0046] The applicant found that the relevant technology relies too heavily on manual operation, which has the following drawbacks:
[0047] 1. Insufficient efficiency: The process of handling the remaining specimens after intraoperative frozen section diagnosis in the pathology department is cumbersome and the efficiency of manual operation is low, making it difficult to meet the needs of high workload.
[0048] 2. Untimely specimen fixation: Manual operation is inefficient, which can lead to untimely specimen fixation, potentially affecting the accuracy of subsequent pathological tests;
[0049] 2. Human error: Human operation is prone to errors (such as uneven staining or improper packaging), which can lead to unstable specimen condition.
[0050] 3. Delayed processing of specimen trays: The cleaning, disinfection and drying of specimen trays rely on manual labor, which is time-consuming and labor-intensive, affecting subsequent work and resulting in low efficiency.
[0051] The following is for reference. Figures 1-3Describes a frozen tissue processing apparatus 100 according to an embodiment of the present invention.
[0052] like Figure 1 As shown, this embodiment provides a frozen tissue processing device 100, which includes a base 1, a specimen support plate 2, a heating component, a spraying device 3, a recovery device 4, and a pusher plate 5.
[0053] One end of the specimen support plate 2 is rotatably mounted on the base 1 to form a rotatable connection end 21, and the other end of the specimen support plate 2 extends away from the rotatable connection end 21 to form an extension end 22.
[0054] The heating component is embedded in the specimen tray support plate 2, and the heating component can heat and thaw the specimen tray 200 on the specimen tray support plate 2.
[0055] The spraying device 3 includes a nozzle 31, which is located above the specimen holder support plate 2 and can spray staining solution.
[0056] The recycling device 4 is located below the specimen tray support plate 2. The recycling device 4 has a first cavity 41 and a second cavity 42. The top of the recycling device 4 has a first inlet 411, which connects to the first cavity 41. The top of the recycling device 4 also has a second inlet 421, which connects to the second cavity 42. The first inlet 411 and the second inlet 421 are arranged sequentially in a direction away from the rotating connection end 21. The first cavity 41 is used to recycle the specimen tray 200, and the second cavity 42 is used to recycle bagged specimens.
[0057] The first inlet 411 and the second inlet 421 are arranged sequentially in the direction away from the rotating connection end 21, which means that the first inlet 411 is closer to the rotating connection end 21 than the second inlet 421, and the second inlet 421 is farther away from the rotating connection end 21 than the first inlet 411; in other words, the first inlet 411 is located between the second inlet 421 and the rotating connection end 21.
[0058] The specimen tray support plate 2 has a downward tilting position and a horizontal position. When the specimen tray support plate 2 is in the downward tilting position, the extension end 22 is located above the first inlet 411; when the specimen tray support plate 2 is in the horizontal position, the extension end 22 is located above the second inlet 421.
[0059] The push plate 5 is located on the base 1. The push plate 5 can push the specimen on the specimen support plate 2 away from the rotating connection end 21 so that the specimen is removed from the specimen support plate 2.
[0060] In a specific application scenario, the specimen support plate 2 is first placed horizontally, and the specimen tray 200 containing the frozen specimen is placed on the specimen support plate 2. Next, specimen retrieval is performed: the heating component is activated to heat the specimen tray 200 and the tissue for a preset time, accelerating the separation of the specimen encased in frozen embedding gel from the specimen tray 200. Simultaneously, staining solution is sprayed onto the tissue through the nozzle 31 to complete the staining process. After the preset heating time, the push plate 5 is activated, which pushes the specimen on the specimen support plate 2 away from the rotating connection end 21. Medical personnel need to prepare a specimen bag in advance and align the opening of the specimen bag with the bottom of the specimen support plate 2 so that the specimen can be placed into the specimen bag. After the specimen falls into the specimen bag, the medical personnel seal the specimen bag and place it into the second cavity 42. Finally, the specimen tray 200 is recovered: when the specimen tray support plate 2 is rotated to the downward tilt position, the extension end 22 is located above the first inlet 411, and the specimen tray 200 slides off the extension end 22 due to gravity and falls into the first cavity 41 through the first inlet 411.
[0061] Here, "bagged specimen" refers to the specimen and its bag forming a whole.
[0062] It should be further explained that the cooperation between the retrieval device 4 and the specimen tray support plate 2 requires first determining the position of the rotating connection end 21 of the specimen tray support plate 2, which is taken as the rotation axis of the specimen tray support plate 2. The first inlet 411 and the second inlet 421 at the top of the retrieval device 4 are arranged sequentially in a direction away from this axis. The first inlet 411 is closer to the rotating end and connects to the first cavity 41 for retrieval of the specimen tray 200, while the second inlet 421 is away from the rotating end and connects to the second cavity 42 for retrieval of bagged specimens. Those skilled in the art can adjust the position, size, and shape of the first inlet 411, the second inlet 421, and the specimen tray support plate 2 according to actual needs, so that when the specimen tray support plate 2 is tilted downwards, the extension end 22 of the specimen tray support plate 2 is aligned with the first inlet 411, and when the specimen tray support plate 2 is horizontal, the extension end 22 is located above the second inlet 421.
[0063] As can be seen from the technical solution, the embodiments provided by this utility model have the following advantages:
[0064] (1) Compared with the dyeing and separation steps in related technologies that rely on manual labor, this application realizes the whole process of "thawing-dyeing-separation-recycling" through the synergistic effect of heating components, spraying device 3, push plate 5 and recycling device 4, which improves the degree of automation and reduces the intensity of manual operation;
[0065] (2) Heating and thawing and spray dyeing can be carried out simultaneously, reducing waiting time and improving efficiency;
[0066] (3) Parameters such as heating time and staining solution spray volume can be controlled more precisely, reducing the instability of specimen status caused by differences in manual operation.
[0067] like Figure 1 As shown, the frozen tissue processing apparatus 100 further includes a pusher plate drive device 8. The pusher plate drive device 8 is used to drive the pusher plate 5 to move away from the rotating connection end 21, thereby pushing the specimen away from the specimen holder 200.
[0068] The push plate drive device 8 here can be a linear motor or a cylinder.
[0069] like Figure 1 As shown, the frozen tissue processing apparatus 100 further includes a telescopic drive rod 9. One end of the telescopic drive rod 9 is hinged to the lower surface of the specimen support plate 2, and the other end of the telescopic drive rod 9 is hinged to the base 1. The telescopic drive rod 9 is used to drive the specimen support plate 2 to rotate during telescopic movement.
[0070] The telescopic drive rod 9 here can be driven by a linear motor push rod or a cylinder push rod.
[0071] The heating element can be a heating wire structure embedded in the specimen holder support plate.
[0072] Example 2
[0073] Furthermore, the frozen tissue processing device 100 also includes an adsorption component embedded in the specimen tray support plate 2. When the specimen tray support plate 2 is in a horizontal position, the adsorption component adsorbs the specimen tray 200; when the specimen tray support plate 2 is in a downward tilting position, the adsorption component releases the adsorption on the specimen tray 200. By setting up the adsorption device, the stability and reliability of the connection between the specimen tray 200 and the specimen tray support plate 2 are improved, the possibility of accidentally pushing the specimen tray 200 down along with the specimen due to the pusher plate 5 pushing the specimen is reduced, and the accuracy of the separation action between the specimen tray 200 and the specimen is improved.
[0074] Furthermore, the adsorption component is constructed as a vacuum adsorption device or an adjustable magnetic adsorption device.
[0075] Example 3
[0076] like Figure 3 As shown, the recovery device 4 is further equipped with a disinfectant inlet 412 and a disinfectant outlet 413. The disinfectant inlet 412 is connected to the first cavity 41, and the disinfectant outlet 413 is also connected to the first cavity 41. The disinfectant inlet 412 introduces disinfectant into the first cavity 41, immersing the specimen tray 200 located inside the first cavity 41, thereby disinfecting the specimen tray 200. After disinfection is completed, the disinfectant outlet 413 discharges the disinfectant from the first cavity 41.
[0077] like Figure 1 and Figure 3 As shown, the cavity wall of the first cavity 41 is further provided with a heating wire 414. The heating wire 414 is embedded in the cavity wall of the first cavity 41. After the disinfectant is discharged, the heating wire 414 is energized and heated to increase the temperature inside the first cavity 41, thereby accelerating the evaporation of the disinfectant on the surface of the specimen tray 200 and drying the specimen tray 200.
[0078] Alcohol can be used as the disinfectant here.
[0079] Example 4
[0080] like Figure 1 As shown, the frozen tissue processing apparatus 100 further includes a guide device 6 disposed between the specimen holder support plate 2 and the second cavity 42. The guide device 6 has an inclined guide surface 61, one end of which is configured to be directly below the extension end 22 of the specimen holder support plate 2 when the specimen holder support plate 2 is in a horizontal position. The inclined guide surface 61 extends downwards along the side away from the rotating connection end 21 into the second cavity 42, defining at least a portion of the second inlet 421. That is, when the specimen holder support plate 2 is in a horizontal position, one end of the inclined guide surface 61 is directly below the extension end 22 of the specimen holder support plate 2, while the other end of the inclined guide surface 61 extends inclined away from the rotating connection end 21, ultimately entering the interior of the second cavity 42.
[0081] The term "the guide device 6 defines at least part of the second inlet 421" means that the inclined guide surface 61 of the guide device 6 directly forms part of the boundary of the second inlet 421. That is, the inclined guide surface 61 and the open opening at the top of the recovery device 4 together form the outline of the second inlet 421, so that the specimen can only fall into the second cavity 42 from the designated path.
[0082] In a specific application scenario, medical staff open the specimen bag and align the opening of the specimen bag directly below the other end of the inclined guide surface 61 to catch the sliding specimen, then seal the specimen bag and place it in the second cavity 42.
[0083] like Figure 1 and Figure 3As shown, further, one end of the inclined guide surface 61 is connected to a transverse baffle 62, which extends upwards and has drainage baffles 63 at both ends. The two drainage baffles 63 are perpendicular to the inclined guide surface 61 and extend approximately along the inclined direction of the inclined guide surface 61, gradually approaching each other in the extending direction. A fixative inlet 621 is provided on the transverse baffle 62. That is to say, the transverse baffle 62 is connected to the starting end of the inclined guide surface 61 (on the side of the inclined guide surface 61 near the extension end 22 of the specimen holder 200), and the transverse baffle 62 extends upwards to prevent the specimen from accidentally entering the first inlet 411 during the sliding process. The funnel-shaped structure of the drainage baffle 63 further restricts the sliding path of the specimen by narrowing the channel width, making the landing point of the specimen smaller, so that medical personnel can catch the specimen more accurately.
[0084] The transverse direction of the transverse baffle 62 is the extension direction of the boundary line between the first inlet 411 and the second inlet 421. The drainage baffle 63 is perpendicular to the inclined guide surface 61 and extends approximately along the inclined direction of the inclined guide surface 61.
[0085] Furthermore, the frozen tissue processing apparatus 100 also includes a fixative supply device 7; the fixative supply device 7 includes a fixative storage tank, a fixative supply pump, and a fixative supply pipe; the fixative supply pipe is connected between the fixative storage tank and the fixative inlet 621, and the fixative supply pump is connected to the fixative supply pipe and is used to drive the fixative from the fixative storage tank to the fixative inlet 621 on the transverse baffle 62.
[0086] The fixative here is formalin.
[0087] In a specific application scenario, medical personnel open the specimen bag and align the opening of the specimen bag directly below the other end of the inclined guide surface 61. First, the fixative supply pump is started, and the fixative in the fixative storage tank is delivered to the inlet of the transverse baffle 62 through the fixative supply pipe to fill the specimen bag with fixative. After the fixative flows out of the inlet, it is guided by the drainage baffle 63, which can increase the flow rate and coverage accuracy of the fixative and reduce liquid spillage. Then, the fixative supply pump is turned off.
[0088] Next, the pusher drive device 8 is activated, the pusher 5 pushes the specimen onto the guide device 6 and slides down along the guide device 6, and finally the specimen bag is poured into the second cavity 42.
[0089] The following is based on Figures 1-3 Let me describe a specific implementation.
[0090] Furthermore, the spray device 3 also includes a dye inlet pipe 32 and a dye supply device 33. The dye supply device includes a dye storage tank and a dye supply pump. The dye inlet pipe 32 is connected between the dye storage tank and the nozzle 31. The dye supply pump is located on the dye inlet pipe and is used to drive the dye from the dye storage tank to the nozzle.
[0091] The staining agent here can be hematoxylin.
[0092] The frozen tissue processing device 100 is externally connected to a disinfectant storage tank 300 and is connected between the disinfectant inlet 412 and the disinfectant storage tank 300 via a disinfectant pipeline (not shown). A disinfectant drive pump (not shown) is installed on the disinfectant pipeline to drive the disinfectant from the disinfectant storage tank 300 into the disinfectant inlet 412.
[0093] The base has a pipe laying cavity for the dyeing agent input pipe.
[0094] A control panel is also embedded on the outer surface of the base 1. The control panel is connected to the telescopic drive rod 9, the heating component, the spray device 3, the push plate drive device 8, the adsorption component, and the fixative supply device 7 to control the opening or closing of the above devices.
[0095] The second cavity 42 may also be equipped with a specimen bag fixing device. For example, the second cavity 42 is equipped with two vacuum adsorption components, the adsorption ends of the vacuum adsorption components are arranged opposite each other and are used to adsorb different sides of the specimen bag while keeping the entrance of the specimen bag open.
[0096] Other configurations and operations of the frozen tissue processing apparatus 100 according to embodiments of the present invention are known to those skilled in the art and will not be described in detail here. In the description of the present invention, "first feature" and "second feature" may include one or more of the aforementioned features. The vertical, horizontal, and front-back directions are defined as shown in the figures.
[0097] In the description of this utility model, unless otherwise expressly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features not in direct contact but through another feature between them. Moreover, "above," "over," and "on top" of the second feature include the first feature directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature.
[0098] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "illustrative embodiment," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.
[0099] Although embodiments of the present invention have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the claims and their equivalents.
Claims
1. A frozen tissue processing device, characterized in that, include: Base (1); The specimen support plate (2) has one end rotatably mounted on the base (1) to form a rotatable connection end (21), and the other end extends away from the rotatable connection end (21) to form an extension end (22). A heating component is embedded in the specimen tray support plate (2) and is used to heat and defrost the specimen tray (200) on the specimen tray support plate (2); The spraying device (3) includes a nozzle (31) disposed above the specimen holder support plate (2), the nozzle (31) being used to spray the staining solution; The recycling device (4) is located below the specimen tray support plate (2) and has a first cavity (41) and a second cavity (42). The top of the recycling device (4) has a first inlet (411) connecting the first cavity (41) and a second inlet (421) connecting the second cavity (42). The first inlet (411) and the second inlet (421) are arranged sequentially in a direction away from the rotating connection end (21). The first cavity (41) is used to recycle the specimen tray (200), and the second cavity (42) is used to recycle bagged specimens. The specimen support plate (2) has a downward tilting position and a horizontal position: in the downward tilting position, the extension end (22) is located above the first inlet (411); in the horizontal position, the extension end (22) is located above the second inlet (421); A push plate (5) is provided on the base (1) and is used to push the specimen on the specimen support plate (2) so that the specimen is disengaged from the specimen support plate (2) away from the rotating connection end (21).
2. The frozen tissue processing apparatus according to claim 1, characterized in that, It also includes an adsorption assembly embedded in the specimen holder support plate (2); The adsorption component is configured to adsorb the specimen tray (200) when the specimen tray support plate (2) is in the horizontal position and to release the adsorption on the specimen tray (200) when the specimen tray support plate (2) is in the downward position.
3. The frozen tissue processing apparatus according to claim 2, characterized in that, The adsorption component is constructed as a vacuum adsorption device or an adjustable magnetic adsorption device.
4. The frozen tissue processing apparatus according to claim 1, characterized in that, The recycling device (4) is also provided with a disinfectant inlet (412) and a disinfectant outlet (413) that are connected to the first cavity (41).
5. The frozen tissue processing apparatus according to claim 4, characterized in that, The cavity wall of the first cavity (41) is provided with a heating wire (414).
6. The frozen tissue processing apparatus according to claim 1, characterized in that, It also includes a guide device (6) disposed between the specimen holder support plate (2) and the second cavity (42); The guide device (6) has an inclined guide surface (61), one end of which is configured to be located directly below the extension end (22) of the specimen support plate (2) when the specimen support plate (2) is in a horizontal position. The inclined guide surface (61) extends downward along the side away from the rotating connection end (21) into the second cavity (42). The guide device (6) defines at least a portion of the second inlet (421).
7. The frozen tissue processing apparatus according to claim 6, characterized in that, One end of the inclined guide surface (61) is connected to an upwardly extending transverse baffle (62) and a flow-draining baffle (63) connected to both ends of the transverse baffle (62). The two drainage baffles (63) are perpendicular to the inclined guide surface and extend approximately along the inclined direction of the inclined guide surface, and the two drainage baffles (63) gradually approach each other in the extending direction; The transverse baffle (62) is provided with a fixed liquid inlet (621).
8. The frozen tissue processing apparatus according to claim 7, characterized in that, It also includes a fixative supply device (7); The fixative supply device (7) includes a fixative storage tank, a fixative supply pump, and a fixative supply pipe; The fixative supply pipe is connected between the fixative storage tank and the fixative inlet (621), and the fixative supply pump is connected to the fixative supply pipe and is used to drive the fixative from the fixative storage tank to the fixative inlet (621) on the transverse baffle (62).
9. The frozen tissue processing apparatus according to claim 1, characterized in that, It also includes a push plate drive device (8); The push plate drive device (8) is used to drive the push plate (5) to move away from the rotating connection end (21).
10. The frozen tissue processing apparatus according to claim 1, characterized in that, It also includes a telescopic drive rod (9); One end of the telescopic drive rod (9) is hinged to the lower surface of the specimen holder support plate (2), and the other end of the telescopic drive rod (9) is hinged to the base (1). The telescopic drive rod (9) is used to drive the specimen holder support plate (2) to rotate during telescopic movement.