A piperazine ferulate tablet quality detection device

Abstract

The utility model discloses a kind of quality detection devices for Piperazine Ferulate tablets, specifically relates to piperazine ferulate detection technical field, including U-shaped frame and extruding cylinder, and extruding cylinder is located at the top of U-shaped frame, the top of U-shaped frame is fixedly connected with support frame, and the inside both sides of support frame are fixedly connected with extruding cylinder, the bottom of extruding cylinder is provided with moving assembly, moving assembly includes first stepper motor, high-strength positive and negative screw rod, multiple sliding blocks, slide bar, two extruding plates and two gaskets, first stepper motor is fixedly installed in one side of U-shaped frame. The utility model is extruded to tablet by anti-sticking pressing plate, the hardness of detecting tablet, friability, first stepper motor works and drives two extruding plates to move in opposite directions, tablet debris in extruding cylinder falls into storage frame, solution is added to storage frame, mixed solution is discharged into special sampling bottle by water outlet pipe, it is easy to operate, effectively improve the detection efficiency of piperazine ferulate.

Description

Technical Field

[0001] This utility model relates to the field of piperazine ferulate tablets testing technology, and more specifically, to a quality testing device for piperazine ferulate tablets. Background Technology

[0002] Piperazine ferulate tablets are a chemically synthesized oral Western medicine, with piperazine ferulate as its main ingredient. Clinically, it is often used as an adjunct treatment for diseases related to microvascular complications. Normal piperazine ferulate tablets are white or off-white, with a smooth surface, free of spots, foreign matter, and breakage. Systematic testing of the quality indicators of piperazine ferulate tablets is conducted to ensure the safety, efficacy, stability, and uniformity of the drug, thereby preventing substandard drugs from entering the market and protecting patient medication safety.

[0003] A search revealed that Chinese patent CN216350649U discloses a drug quality testing device. By manually rotating a hand-cranked disc clockwise, a screw extrusion mechanism rotates clockwise and moves downwards, causing the extrusion plate to descend along with the screw. This crushes the drug within the extrusion cylinder. During this process, the crushed drug particles fall through a coarse-mesh metal mesh support plate onto the upper surface of a fine-mesh sorting basket. Activating a micro-vibration motor generates vibration, causing the mixing and extrusion cylinders to vibrate together, allowing the coarse-mesh metal mesh support plate and the fine-mesh sorting basket to quickly sieve the crushed drug.

[0004] When the above-mentioned detection device detects piperazine ferulate tablets, the crushed small particles of the drug will pass through the coarse-pore metal mesh support plate and fall onto the upper surface of the fine-pore sorting basket. However, during the compression process, the drug fragments will get stuck on the metal mesh support plate, thereby reducing the actual flow area of ​​the metal mesh support plate. This will prevent the subsequent crushed small particles from passing through smoothly, thus affecting the detection efficiency of piperazine ferulate tablets. Utility Model Content

[0005] In order to overcome the above-mentioned defects of the prior art, the present invention provides a quality testing device for piperazine ferulate tablets, which aims to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a quality testing device for piperazine ferulate tablets, comprising a U-shaped frame and an extrusion cylinder, wherein the extrusion cylinder is located at the top of the U-shaped frame, a support frame is fixedly connected to the top of the U-shaped frame, and both sides of the support frame are fixedly connected to the extrusion cylinder, and a moving component is provided at the bottom of the extrusion cylinder, the moving component comprising a first stepper motor, a high-strength forward and reverse lead screw, multiple sliders, a slide rod, two extrusion plates and two gaskets, the first stepper motor is fixedly installed on one side of the U-shaped frame, and the output shaft end of the first stepper motor is fixedly connected to the high-strength forward and reverse lead screw, both ends of the high-strength forward and reverse lead screw are movably connected to the U-shaped frame through bearings, both ends of the slide rod are fixedly connected to the U-shaped frame, multiple sliders are movably sleeved on the high-strength forward and reverse lead screw and the slide rod, and one side of each slider is fixedly connected to the two extrusion plates.

[0007] Furthermore, the bottom ends of the two gaskets are respectively fixedly connected to the two extrusion plates, and the opposite sides of the two gaskets are in contact with the extrusion cylinder.

[0008] As can be seen, in the above technical solution, the gasket can improve the sealing between the extrusion plate and the extrusion cylinder, thereby preventing debris from overflowing.

[0009] Furthermore, an anti-sticking pressure plate is provided on the top of the extrusion cylinder, and a hydraulic cylinder is fixedly connected to the center of the top of the anti-sticking pressure plate, and the top of the hydraulic cylinder is fixedly connected to the support frame.

[0010] Furthermore, a storage frame is fixedly connected to the center of the bottom of the U-shaped frame, and a water outlet pipe is fixedly connected to the bottom of the U-shaped frame near the front edge, with a valve fixedly installed on the water outlet pipe.

[0011] As can be seen, in the above technical solution, the valve is opened and the mixed liquid is discharged into a special sampling bottle through the water outlet pipe for subsequent high performance liquid chromatography to detect the content of piperazine ferulate, related substances and other indicators.

[0012] Furthermore, a base is provided at the bottom of the U-shaped frame, and a vibration assembly is provided at the top of the base. The vibration assembly includes multiple telescopic rods, a second stepper motor, an eccentric wheel, and multiple springs.

[0013] Furthermore, the top and bottom ends of the multiple telescopic rods are fixedly connected to the U-shaped frame and the base, respectively. The second stepper motor is fixedly installed on the front side of the base, and the output shaft end of the second stepper motor is fixedly connected to the eccentric wheel. The front and rear ends of the eccentric wheel are movably connected to the base through bearings.

[0014] Furthermore, the multiple springs are movably sleeved on the outside of the multiple telescopic rods, and the top and bottom ends of the multiple springs are fixedly connected to the multiple telescopic rods and the base, respectively.

[0015] It can be seen that the above technical solution facilitates the resetting of the U-shaped frame.

[0016] The technical effects and advantages of this utility model are as follows:

[0017] 1. This utility model uses an anti-sticking pressure plate to squeeze tablets and test their hardness and brittleness. The first step motor drives two squeezing plates to move in opposite directions, and the tablet fragments in the squeezing cylinder fall into the storage frame. A solution is added to the storage frame to mix the fragments with the solution. The mixture is discharged into a special sampling bottle through a water outlet pipe for subsequent high performance liquid chromatography (HPLC) to detect the content of piperazine ferulate, related substances, and other indicators. The operation is simple and effectively improves the detection efficiency of piperazine ferulate tablets.

[0018] 2. This utility model uses a second stepper motor to drive an eccentric wheel to rotate. When the top of the eccentric wheel contacts the U-shaped frame, the U-shaped frame begins to move upward, thereby causing multiple telescopic rods to extend, which in turn causes multiple springs to stretch. When the eccentric wheel moves away from the U-shaped frame, the multiple springs rebound and cause the U-shaped frame to return to its original position downward. This cycle repeats, vibrating the U-shaped frame and the piperazine ferulic acid tablets. The structure is simple and easy to use. Attached Figure Description

[0019] The structures, proportions, sizes, etc. illustrated in this specification are only for the purpose of assisting those skilled in the art in understanding and reading the content disclosed herein, and are not intended to limit the implementation conditions of this utility model. Therefore, they have no substantial technical significance. Any modifications to the structure, changes in the proportions, or adjustments to the size, without affecting the effects and objectives that this utility model can produce, should still fall within the scope of the technical content disclosed in this utility model.

[0020] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0021] Figure 2 This is a perspective view of the present invention from a downward angle;

[0022] Figure 3 This is a schematic diagram of the assembly structure of the U-shaped frame and the extrusion cylinder of this utility model;

[0023] Figure 4 This is a schematic diagram of the assembly structure of the base and vibration component of this utility model;

[0024] Figure 5 This is a schematic diagram of the structure of the mobile component of this utility model.

[0025] In the diagram: 1. U-shaped frame; 2. Extrusion cylinder; 3. Support frame; 4. Anti-stick pressure plate; 5. Hydraulic cylinder; 6. Moving component; 7. Storage box; 8. Base; 9. Vibration component; 10. Water outlet pipe; 11. Valve; 601. First stepper motor; 602. High-strength forward and reverse lead screw; 603. Slider; 604. Slide rod; 605. Extrusion plate; 606. Gasket; 901. Telescopic rod; 902. Second stepper motor; 903. Eccentric wheel; 904. Spring. Detailed Implementation

[0026] The following specific embodiments illustrate the implementation of this utility model. Those skilled in the art can easily understand other advantages and effects of this utility model from the content disclosed in this specification. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of this utility model.

[0027] Refer to the instruction manual appendix Figure 1-5 This embodiment of a quality testing device for piperazine ferulate tablets includes a U-shaped frame 1 and a compression cylinder 2, with the compression cylinder 2 located at the top of the U-shaped frame 1. A support frame 3 is fixedly connected to the top of the U-shaped frame 1, and both sides of the support frame 3 are fixedly connected to the compression cylinder 2. A moving component 6 is provided at the bottom of the compression cylinder 2. The moving component 6 includes a first stepper motor 601, a high-strength forward and reverse lead screw 602, multiple sliders 603, a slide rod 604, two compression plates 605, and two gaskets 606. The first stepper motor 601 is fixedly installed on one side of the U-shaped frame 1, and the output shaft end of the first stepper motor 601 is fixedly connected to the high-strength forward and reverse lead screw 602. Both ends of the high-strength forward and reverse lead screw 602 are movably connected to the U-shaped frame 1 through bearings. Both ends of the slide rod 604 are fixedly connected to the U-shaped frame 1. Multiple sliders 603 are movably sleeved on the high-strength forward and reverse lead screw 602 and the slide rod 604, and one side of each slider 603 is fixedly connected to the two compression plates 605.

[0028] Furthermore, the bottom ends of the two gaskets 606 are fixedly connected to the two extrusion plates 605 respectively, and the opposite sides of the two gaskets 606 are in contact with the extrusion cylinder 2. The top of the extrusion cylinder 2 is provided with an anti-sticking pressure plate 4. A hydraulic cylinder 5 is fixedly connected to the center of the top of the anti-sticking pressure plate 4, and the top of the hydraulic cylinder 5 is fixedly connected to the support frame 3. A storage frame 7 is fixedly connected to the center of the bottom of the U-shaped frame 1. A water outlet pipe 10 is fixedly connected to the bottom of the U-shaped frame 1 near the front edge, and a valve 11 is fixedly installed on the water outlet pipe 10.

[0029] Furthermore, a base 8 is provided at the bottom of the U-shaped frame 1, and a vibration component 9 is provided at the top of the base 8. The vibration component 9 includes multiple telescopic rods 901, a second stepper motor 902, an eccentric wheel 903, and multiple springs 904. The top and bottom ends of the multiple telescopic rods 901 are fixedly connected to the U-shaped frame 1 and the base 8, respectively. The second stepper motor 902 is fixedly installed on the front side of the base 8, and the output shaft end of the second stepper motor 902 is fixedly connected to the eccentric wheel 903. The front and rear ends of the eccentric wheel 903 are movably connected to the base 8 through bearings. The multiple springs 904 are movably sleeved on the outside of the multiple telescopic rods 901, and the top and bottom ends of the multiple springs 904 are fixedly connected to the multiple telescopic rods 901 and the base 8, respectively.

[0030] The base 8 is fixed with multiple bolts, and the bottom of the U-shaped frame 1 near the four corners is supported by multiple telescopic rods 901. When the second stepper motor 902 is started, it drives the eccentric wheel 903 to rotate. When the top of the eccentric wheel 903 contacts the U-shaped frame 1, the U-shaped frame 1 begins to move upward, thereby causing the multiple telescopic rods 901 to extend, which in turn causes the multiple springs 904 to stretch. When the eccentric wheel 903 moves away from the U-shaped frame 1, the multiple springs 904 rebound and cause the U-shaped frame 1 to return to its original position downward. This cycle repeats, vibrating the U-shaped frame 1 and the piperazine ferulate tablets. On the one hand, it can cause the residual piperazine ferulate tablet fragments on the inner wall of the extrusion cylinder 2 to detach from the wall and fall into the storage frame 7 with the vibration, reducing the residue of fragments. On the other hand, it can accelerate the mixing of fragments and solvent in the storage frame 7, shortening the dissolution time. The structure is simple and easy to use.

[0031] The usage method of this embodiment is as follows:

[0032] When in use, the staff places the piperazine ferulate tablets into the extrusion cylinder 2. At this time, the two symmetrical extrusion plates 605 are in a closed state, forming a horizontal support for the tablets from the bottom. The appearance and color of the tablets are observed for any abnormalities. Then, the hydraulic cylinder 5 is activated. The piston rod on the hydraulic cylinder 5 extends, which can drive the anti-sticking plate 4 with a polytetrafluoroethylene anti-stick coating at the bottom to move downward. The tablets are squeezed by the anti-sticking plate 4, and the hardness and brittleness of the tablets are tested.

[0033] The first stepper motor 601 is started, which drives the high-strength forward and reverse screw 602 to rotate. Since two of the sliders 603 are threadedly connected to the high-strength forward and reverse screw 602, and the other two sliders 603 and the slide rod 604 cooperate to restrict the rotation of the two extrusion plates 605, the high-strength forward and reverse screw 602 can drive the two extrusion plates 605 to move in opposite directions. The tablet fragments in the extrusion cylinder 2 fall into the storage frame 7, and the bottom of the extrusion cylinder 2 can clean the fragments adhering to the extrusion plates 605. At the same time, the gasket 606 can improve the sealing between the extrusion plates 605 and the extrusion cylinder 2, thereby preventing the fragments from overflowing.

[0034] Then, add the solution into the storage box 7 and mix the debris with the solution. Finally, open the valve 11 and discharge the mixture into a special sampling bottle through the water outlet pipe 10 for subsequent high performance liquid chromatography (HPLC) detection of the content of piperazine ferulate, related substances, and other indicators. The operation is simple and effectively improves the detection efficiency of piperazine ferulate tablets.

[0035] All contents not described in detail in the specification are existing technologies known to those skilled in the art, and the model parameters of each electrical appliance are not specifically limited; conventional equipment can be used. Electrical control components not mentioned in this technical solution are not shown in the figures because they are existing technologies, and will not be described here.

[0036] The above are merely preferred embodiments of the present utility model and are not intended to limit the present utility model. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A piperazine ferulate tablet quality detection device, comprising a U-shaped frame (1) and a squeezing cylinder (2), and the squeezing cylinder (2) is located at the top of the U-shaped frame (1), characterized in that: A support frame (3) is fixedly connected to the top of the U-shaped frame (1), and both sides of the support frame (3) are fixedly connected to the extrusion cylinder (2). A moving component (6) is provided at the bottom of the extrusion cylinder (2). The moving component (6) includes a first stepper motor (601), a high-strength forward and reverse lead screw (602), multiple sliders (603), a slide rod (604), two extrusion plates (605), and two gaskets (606). The first stepper motor (601) is fixedly installed on the U-shaped frame (1). On one side, the output shaft end of the first stepper motor (601) is fixedly connected to the high-strength forward and reverse lead screw (602). Both ends of the high-strength forward and reverse lead screw (602) are movably connected to the U-shaped frame (1) through bearings. Both ends of the slide rod (604) are fixedly connected to the U-shaped frame (1). Multiple sliders (603) are movably sleeved on the high-strength forward and reverse lead screw (602) and the slide rod (604), and one side of each slider (603) is fixedly connected to two extrusion plates (605).

2. The piperazine ferulate tablet quality detection device according to claim 1, characterized in that: The bottom ends of the two gaskets (606) are fixedly connected to the two extrusion plates (605) respectively, and the opposite sides of the two gaskets (606) are in contact with the extrusion cylinder (2).

3. The ferulic acid piperazine tablet quality detection device according to claim 1, characterized by: The top of the extrusion cylinder (2) is provided with an anti-sticking pressure plate (4), and a hydraulic cylinder (5) is fixedly connected at the center of the top of the anti-sticking pressure plate (4), and the top of the hydraulic cylinder (5) is fixedly connected to the support frame (3).

4. The ferulic acid piperazine tablet quality detection device according to claim 1, characterized by: A storage frame (7) is fixedly connected to the center of the bottom of the U-shaped frame (1). A water outlet pipe (10) is fixedly connected to the bottom of the U-shaped frame (1) near the front edge. A valve (11) is fixedly installed on the water outlet pipe (10).

5. The ferulic acid piperazine tablet quality detection device according to claim 1, characterized by: The bottom of the U-shaped frame (1) is provided with a base (8), and the top of the base (8) is provided with a vibration assembly (9). The vibration assembly (9) includes multiple telescopic rods (901), a second stepper motor (902), an eccentric wheel (903), and multiple springs (904).

6. The piperazine ferulate tablet quality detection device according to claim 5, characterized in that: The top and bottom ends of the multiple telescopic rods (901) are fixedly connected to the U-shaped frame (1) and the base (8) respectively. The second stepper motor (902) is fixedly installed on the front side of the base (8), and the output shaft end of the second stepper motor (902) is fixedly connected to the eccentric wheel (903). The front and rear ends of the eccentric wheel (903) are movably connected to the base (8) through bearings.

7. The quality testing device for piperazine ferulate tablets according to claim 5, characterized in that: Multiple springs (904) are movably sleeved on the outside of multiple telescopic rods (901), and the top and bottom ends of multiple springs (904) are fixedly connected to multiple telescopic rods (901) and base (8) respectively.

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