An ovarian tissue freezing carrier

Abstract

The utility model discloses an ovary tissue freezing carrier belongs to medical instrument technical field, including handheld part, sealing cover, connecting portion and outer sleeve, the sealing cover is fixed in one end of handheld part, the connecting portion is fixed in one end of sealing cover, the outer wall of connecting portion is equipped with outer thread groove, the inner wall of outer sleeve is equipped with the inner thread groove of matching with outer thread groove, the one end of connecting portion away from sealing cover is fixed with the bearing part, a plurality of ovary tissue loading area are equipped on the bearing part, and rotationally connected with connecting column on bearing part, and the outer wall of connecting column is fixed with the protection board, a plurality of installation slot corresponding with ovary tissue loading area are equipped on the protection board, and rotationally connected with the protection cover in installation slot. This ovary tissue freezing carrier has the protection function, can effectively protect the ovary tissue, reduces its probability of being contaminated.

Description

Technical Field

[0001] This utility model belongs to the field of medical device technology, specifically relating to an ovarian tissue cryopreservation carrier. Background Technology

[0002] Ovarian cryopreservation is a medical technique primarily for unmarried women in their adolescence or reproductive years who have been diagnosed with cancer. Chemotherapy and radiotherapy can lead to premature ovarian failure and loss of fertility. Ovarian tissue cryopreservation before chemotherapy or radiotherapy can preserve a large number of gametes at once, which can then be transplanted back into the woman's body at an appropriate time. Therefore, follicles are preserved, and the woman's hormone secretion capacity is restored.

[0003] Ovarian tissue cryopreservation is an important technique in the field of assisted reproduction, especially suitable for women who need to preserve their fertility due to tumor radiotherapy and chemotherapy, autoimmune diseases, etc. However, existing ovarian tissue cryopreservation carriers have the following shortcomings in practical applications:

[0004] Insufficient protection: Traditional carriers often use open or simple encapsulation structures, making ovarian tissue susceptible to external contamination (such as microorganisms and impurities) or tissue damage due to mechanical collisions during freezing, transportation, and thawing.

[0005] Structural design flaws: The lack of targeted tissue fixation and isolation devices makes it impossible to store multiple ovarian tissue samples independently, which can easily lead to cross-contamination during retrieval. Utility Model Content

[0006] The purpose of this invention is to provide an ovarian tissue cryopreservation carrier to solve the problems of insufficient protection and structural design defects mentioned in the background art.

[0007] To achieve the above objectives, this utility model provides the following technical solution: an ovarian tissue cryopreservation carrier, comprising a handheld part, a sealing cap, a connecting part, and an outer sleeve, wherein the sealing cap is fixed to one end of the handheld part, the connecting part is fixed to one end of the sealing cap, the outer wall of the connecting part is provided with an external thread groove, and the inner wall of the outer sleeve is provided with an internal thread groove that matches the external thread groove.

[0008] The end of the connecting part away from the sealing cover is fixed with a bearing part. The bearing part has multiple ovarian tissue loading areas and a connecting column is rotatably connected to the bearing part. A protective plate is fixed to the outer wall of the connecting column. The protective plate has multiple mounting slots corresponding to the ovarian tissue loading areas and a protective cover is rotatably connected to the mounting slot.

[0009] In a further embodiment, the supporting part is provided with a plurality of grooves, and a magnetic block that is attracted to the protective plate is fixed in the groove.

[0010] In a further embodiment, the supporting part is provided with a plurality of grooves II, and a magnetic block II that is attracted to the protective cover is fixed in the grooves II.

[0011] In a further embodiment, the surface of the bearing portion is provided with a coding area one, and the outer wall of the outer sleeve is provided with a coding area two.

[0012] In a further embodiment, a sealing groove is provided on the outer wall of the connecting part, and a sealing ring is installed in the sealing groove.

[0013] The technical effects and advantages of this utility model are as follows:

[0014] The ovarian tissue cryopreservation carrier has an independent ovarian tissue loading area in its carrier section. Together with a rotatable protective plate and a protective cover, it forms a physical isolation barrier to prevent the tissue from being directly exposed to the external environment. Magnetic block one and magnetic block two respectively generate adsorption force on the protective plate and protective cover to ensure the stability of the sealing state and prevent accidental opening during transportation. The outer tube is connected to the connecting part through threads and uses a sealing ring to form a sealed cavity to isolate liquid nitrogen and external contaminants, while reducing the impact of temperature fluctuations on the tissue.

[0015] The corresponding setting of coding area one and coding area two realizes "one organization, one code", which facilitates clinical identity verification and traceability management;

[0016] The protective cap can be opened separately, exposing only the target tissue during use and avoiding contamination of other loading areas. The handle is ergonomically designed for easy operation and transfer. This ovarian tissue cryopreservation carrier has a protective function, effectively protecting the ovarian tissue and reducing the probability of contamination. Attached Figure Description

[0017] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0018] Figure 1 This is a schematic diagram of the structure of this utility model;

[0019] Figure 2 This is a schematic diagram of the structure of this utility model without the outer sleeve.

[0020] Figure 3 This is a structural diagram of the present invention without an outer sleeve and protective plate.

[0021] In the diagram: 1. Handheld part; 2. Sealing cap; 3. Connecting part; 4. Sealing ring; 5. Bearing part; 6. Ovarian tissue loading area; 7. Magnetic block one; 8. Magnetic block two; 9. Coding area one; 10. Protective plate; 11. Protective cover; 12. Outer tube; 13. Coding area two. Detailed Implementation

[0022] In the following description, numerous specific details are set forth in order to provide a more thorough understanding of the present invention. However, it will be apparent to those skilled in the art that the present invention can be practiced without one or more of these details. In other instances, certain technical features well-known in the art have not been described in order to avoid confusion with the present invention.

[0023] Unless otherwise defined, the directions mentioned herein, such as up, down, left, right, front, back, inside, and outside, are based on the directions shown in the figures of this utility model, and are explained here together.

[0024] This utility model provides, for example Figure 1-3 An ovarian tissue cryopreservation carrier shown includes a handheld part 1, a sealing cap 2, a connecting part 3, and an outer tube 12. The sealing cap 2 is fixed to one end of the handheld part 1, and the connecting part 3 is fixed to one end of the sealing cap 2. The outer wall of the connecting part 3 has an external thread groove, and the inner wall of the outer tube 12 has an internal thread groove that matches the external thread groove. The outer wall of the connecting part 3 has a sealing groove, and a sealing ring 4 is installed in the sealing groove. A bearing part 5 is fixed to the end of the connecting part 3 away from the sealing cap 2, and multiple ovarian tissue loading areas 6 are formed on the bearing part 5.

[0025] The support unit 5 uses a bio-coating-titanium alloy-decellularized matrix-titanium alloy-bio-coating structure. The titanium alloy adopts an ultra-thin sheet-like porous structure with a biocompatible coating sprayed on the surface. The middle layer is filled with decellularized matrix / collagen. The titanium alloy has excellent mechanical strength and stability, which can effectively protect ovarian tissue from mechanical damage during freezing, transportation and thawing. It is almost undeformed under liquid nitrogen and is suitable for long-term preservation. The oxide layer on the surface of the titanium alloy can reduce tissue adhesion and immune rejection. The biocompatible coating (such as polydopamine) is sprayed to enhance tissue adhesion and avoid local overcooling caused by direct metal contact. The outer titanium alloy supports rapid cooling (suitable for vitrification) and reduces ice crystal formation. In order to avoid local temperature gradients caused by excessive heat conduction, a sheet-like porous structure is used to balance the uniformity of heat transfer. The porous structure can also promote the penetration efficiency of cryoprotectants. The middle layer is filled with decellularized matrix / collagen to simulate the extracellular environment and promote follicle survival.

[0026] A connecting column is rotatably connected to the support part 5. A protective plate 10 is fixed to the outer wall of the connecting column. The protective plate 10 has multiple mounting slots corresponding to the ovarian tissue loading areas 6, and a protective cover 11 is rotatably connected to each mounting slot. The rotatable protective plate 10 can be rotated to a suitable position when placing ovarian tissue, avoiding obstruction of the multiple ovarian tissue loading areas 6 on the support part 5, making ovarian tissue placement more convenient. At the same time, the individually openable protective cover 11 allows only the corresponding protective cover 11 to be opened when removing ovarian tissue, preventing the opening of other protective covers 11 from contaminating the ovarian tissue in the corresponding ovarian tissue loading area 6. The support part 5 has multiple grooves, and a magnet that attracts the protective plate 10 is fixed in each groove. The first suction block 7 and the second suction block 8 are provided on the support part 5. Multiple grooves are provided on the second suction block 7, and magnetic suction blocks 8 are fixed in the grooves and are attracted to the protective cover 11. The first suction block 7 and the second suction block 8 can attract the protective plate 10 and the protective cover 11 respectively to prevent them from being opened accidentally. At the same time, the protective plate 10 and the protective cover 11 can also block the ovarian tissue in the ovarian tissue loading area 6 to prevent it from falling accidentally. The surface of the support part 5 is provided with a coding area 9, and the outer wall of the outer sleeve 12 is provided with a coding area 13. Each code corresponds to an ovarian tissue piece to facilitate medical staff to verify the identity. The code uses a unique identifier, corresponding to the patient information and tissue number, and can trace the entire freezing-thawing process. The codes in the first coding area 9 and the second coding area 13 correspond to each other, which can further ensure the accuracy of the information.

[0027] All standard parts used in this utility model can be purchased from the market, and irregular parts can be customized according to the description and drawings. The specific connection methods of each part adopt conventional methods such as bolts, rivets, and welding that are mature in the prior art. The machinery, parts and equipment adopt conventional models in the prior art. The contents not described in detail in this specification belong to the prior art known to those skilled in the art.

[0028] In the description of this utility model, it should be understood that the indicated orientation or positional relationship is based on the orientation or positional relationship shown in the accompanying drawings, and is only for the convenience of describing this utility model and simplifying the description, and is not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0029] Working principle:

[0030] When using this ovarian tissue cryopreservation carrier, hold the carrier with the hand-held part 1, rotate the protective plate 10 to the appropriate position, open the corresponding protective cover 11, place the ovarian tissue slice in the loading area of ​​the carrier part 5, rotate the protective plate 10 to make it adsorb with the magnetic block 7, and then use the magnetic block 8 to fix the protective cover 11 to complete the initial protection of the tissue. Then, screw the outer sleeve 12 into the external thread of the connecting part 3 through the internal thread, and the sealing ring 4 forms a sealed space in the sealing groove to ensure that the carrier remains sealed in the liquid nitrogen environment. The information of the coding area 1 9 and the coding area 2 13 are recorded accordingly to facilitate medical staff to verify the tissue identity.

[0031] During freezing, the ultra-thin porous structure of the titanium alloy promotes the penetration of cryoprotectant and balances heat transfer, reducing ice crystal formation. The bio-coating and decellularized matrix layer maintain the stability of the tissue microenvironment. During transport and storage, the outer sheath 12 and the protective structure work together to block external contamination, and the magnetic fixation structure prevents components from loosening, ensuring the long-term safe preservation of ovarian tissue at low temperatures. During revival, the target tissue can be accurately removed by operating in the reverse order, reducing the risk of contamination during the operation.

[0032] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. An ovarian tissue cryopreservation carrier, comprising a handle (1), a sealing cap (2), a connecting part (3), and an outer tube (12), characterized in that: The sealing cap (2) is fixed to one end of the handheld part (1), the connecting part (3) is fixed to one end of the sealing cap (2), the outer wall of the connecting part (3) is provided with an external thread groove, and the inner wall of the outer sleeve (12) is provided with an internal thread groove that matches the external thread groove. The connecting part (3) is fixed with a bearing part (5) at the end away from the sealing cover (2). The bearing part (5) has multiple ovarian tissue loading areas (6) and a connecting column is rotatably connected to the bearing part (5). A protective plate (10) is fixed to the outer wall of the connecting column. The protective plate (10) has multiple mounting slots corresponding to the ovarian tissue loading areas (6) and a protective cover (11) is rotatably connected in the mounting slot.

2. The ovarian tissue cryopreservation carrier according to claim 1, characterized in that: The bearing part (5) has multiple grooves, and a magnetic block (7) that is attracted to the protective plate (10) is fixed in the groove.

3. The ovarian tissue cryopreservation carrier according to claim 2, characterized in that: The bearing part (5) has multiple grooves, and magnetic blocks (8) that are attracted to the protective cover (11) are fixed in the grooves.

4. The ovarian tissue cryopreservation carrier according to claim 1, characterized in that: The surface of the bearing part (5) is provided with a coding area one (9), and the outer wall of the outer sleeve (12) is provided with a coding area two (13).

5. The ovarian tissue cryopreservation carrier according to claim 1, characterized in that: The outer wall of the connecting part (3) is provided with a sealing groove, and a sealing ring (4) is installed in the sealing groove.

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