A leukofilter system for children

Abstract

The utility model discloses a leukocyte removal filter system for children, including blood collection bag, wherein the top of blood collection bag is connected leukocyte removal filter, filter blood bag, transfer bag and red cell storage solution bag in proper order through connecting catheter, leukocyte removal filter is arranged between blood collection bag and filter blood bag, and filter blood bag is connected RBC subpackaging blood bag through subpackaging catheter, and transfer bag is connected plasma subpackaging blood bag through subpackaging catheter. The leukocyte removal filter system for children provided by the utility model can realize quantitative subpackaging of blood components, avoid exposure risk caused by external blood bag subpackaging and improve the safety of blood.

Description

Technical Field

[0001] This utility model relates to a medical blood bag, and more particularly to a leukocyte removal filtration system for children. Background Technology

[0002] Blood transfusion remains an essential and irreplaceable clinical treatment. Leukocyte removal from blood components can improve their preservation time, reduce febrile non-hemolytic reactions (FNHTR), inhibit or delay HLA alloimmunization, and decrease post-transfusion graft-versus-host disease (GVHD), among other harmful adverse reactions. Therefore, leukocyte-removed blood products are preferred for transfusion. Leukocyte removal filters primarily remove leukocytes from the blood through filtration and adsorption; this method is simple, easy to implement, and effective, and has been widely used.

[0003] Pediatric patients constitute a heterogeneous group, existing at different stages of growth and development. They exhibit significant differences in blood volume, blood composition levels, immune system maturity, and physiological responses to hypovolemia and hypoxia, placing high demands on blood transfusions and increasing the risk of adverse transfusion reactions. Therefore, blood transfusion practices in pediatric diseases differ from those in adult patients and are far more complex. A scientific and comprehensive assessment of the pediatric patient's condition, transfusion needs, benefits, and risks is crucial. The principle of avoiding unnecessary and excessive transfusions should be upheld, measures taken to avoid or reduce transfusions, and the selection of strict or lenient transfusion thresholds and appropriate blood components should be carefully considered. Timely evaluation of transfusion efficacy is also essential. Therefore, pediatric transfusions should utilize leukocyte-reduced blood components with higher leukocyte-reduction efficacy, and the amount of blood used in children must be strictly limited. Currently, the minimum blood collection volume in China is 200ml of whole blood, which is clearly insufficient to meet the needs of children. This necessitates aliquoting of blood components, which is inconvenient and carries the risk of contamination. Meanwhile, children have a higher risk of exposure to DEHP (di(2-ethylhexyl) phthalate), and DEHP-plasticized PVC materials should be avoided as much as possible when children receive blood transfusions. Utility Model Content

[0004] The technical problem to be solved by this utility model is to provide a leukocyte removal filtration system for children, which can realize the quantitative dispensing of blood components, avoid the exposure risk caused by dispensing with external blood bags, and improve the safety of blood.

[0005] The technical solution adopted by this utility model to solve the above-mentioned technical problems is to provide a leukocyte-removing filtration system for children, including a blood collection bag, wherein the top of the blood collection bag is connected in sequence to a filtered blood bag, a transfer bag and a red blood cell preservation solution bag via a connecting conduit, a leukocyte-removing filter is provided between the blood collection bag and the filtered blood bag, the filtered blood bag is connected to an RBC dispensing blood bag via a dispensing conduit, and the transfer bag is connected to a plasma dispensing blood bag via a dispensing conduit.

[0006] Furthermore, the top of the blood collection bag is connected to the sampling device and the blood collection needle via a T-fitting fitting. An anti-needle-puncture protection device is provided between the blood collection needle and the T-fitting fitting, and a flow-stopping clamp is provided between the sampling device and the blood collection bag.

[0007] Furthermore, the sampling device, blood collection bag, filtered blood bag, RBC dispensing blood bag, transfer bag, plasma dispensing blood bag, red blood cell preservation solution bag, and connecting catheter are all made of BTHC-plasticized PVC material.

[0008] Furthermore, the dispensing conduit is equipped with a flow-stopping clamp.

[0009] Furthermore, the filtered blood bag is provided with a transfusion port, and the transfusion port is made of BTHC-plasticized PVC material.

[0010] Furthermore, the blood collection bag, filtered blood bag, transfer bag, and red blood cell preservation solution bag are provided with a folded core barrier, the folded core of which is made of PC material.

[0011] Furthermore, the outer shell of the leukocyte-removing filter is made of PC material, and the filter material of the leukocyte-removing filter is PBT non-woven fabric.

[0012] Compared with the prior art, the present invention has the following advantages: The leukocyte removal filtration system for children provided by the present invention uses a multi-unit blood bag for storing blood components and sets up a separate storage bag, which realizes the separation and application of blood components in a closed system, avoids the exposure risk caused by external blood bag separation, and improves the safety of blood. Attached Figure Description

[0013] Figure 1 This is a schematic diagram of the structure of the leukocyte removal filtration system for children according to this utility model.

[0014] The diagram is marked as follows:

[0015] 1. Blood collection needle; 2. Needle-prick protection device; 3. Sampling device; 4. Leukocyte-removing filter; 5. Blood collection bag; 6. Filtered blood bag; 7. RBC dispensing blood bag; 8. Transfer bag; 9. Plasma dispensing blood bag; 10. Red blood cell preservation solution bag; 11. T-fitting fitting; 12. Flow stop clamp; 13. Folded core barrier; 14. Transfusion port. Detailed Implementation

[0016] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0017] Figure 1 This is a schematic diagram of the structure of the leukocyte removal filtration system for children according to this utility model.

[0018] Please see Figure 1 This utility model provides a leukocyte-removing filtration system for children, comprising a blood collection bag 5. The top of the blood collection bag 5 is sequentially connected to a filtered blood bag 6, a transfer bag 8, and a red blood cell preservation solution bag 10 via connecting conduits. A leukocyte-removing filter 4 is disposed between the blood collection bag 5 and the filtered blood bag 6. The filtered blood bag 6 is connected to an RBC (red blood cell) dispensing bag 7 via a dispensing conduit, and the transfer bag 8 is connected to a plasma dispensing bag 9 via a dispensing conduit. Based on existing leukocyte-removing filtration multi-unit blood bags, this utility model configures one or more blood component dispensing and storage bags on each blood component storage bag, realizing the dispensing and application of blood components within a closed system. This avoids the exposure risks associated with external blood bag dispensing and improves blood safety.

[0019] The leukocyte removal filtration system for children provided by this utility model has a sampling device 3 and a blood collection needle 1 connected to the top of the blood collection bag 5 via a three-way fitting 11. A needle-puncture protection device 2 is provided between the blood collection needle 1 and the three-way fitting 11, and a flow-stopping clamp 12 is provided between the sampling device 3 and the blood collection bag 5.

[0020] The leukocyte-reducing filtration system for children provided by this utility model is made of BTHC (trihexyl butyryl citrate) plasticized PVC, comprising the sampling device 3, blood collection bag 5, filtered blood bag 6, RBC dispensing blood bag 7, transfer bag 8, plasma dispensing blood bag 9, red blood cell preservation fluid bag 10, and connecting tubing. The filtered blood bag 6 is equipped with a transfusion port 14, which is also made of BTHC plasticized PVC. All materials in contact with blood in this multi-unit blood bag system are DEHP-free. The use of BTHC plasticized PVC replaces the DEHP plasticized PVC used in traditional blood bags, thus avoiding the risk of DEHP exposure in children receiving blood transfusions.

[0021] This utility model provides a leukocyte removal filtration system for children. The blood collection bag 5, filtered blood bag 6, transfer bag 8, and red blood cell preservation fluid bag 10 are equipped with a folded core barrier 13, the core of which is made of PC material. The outer shell of the leukocyte removal filter 4 is made of PC material, and the filter material is PBT non-woven fabric. This ensures that the residual white blood cell count is below 1×10⁻⁶. 6 Each unit reduces the risk of adverse transfusion reactions in children due to residual leukocytes. The entire leukocyte-removing filter 4 undergoes high-temperature, high-pressure steam sterilization to ensure it is completely sterile and pyrogen-free.

[0022] The pediatric leukocyte removal filtration system provided by this utility model features a flow stop clamp 12 on the dispensing tubing for convenient quantitative dispensing. In use, blood collection, leukocyte removal filtration, blood component preparation, and blood component storage are completed according to standard procedures. When quantitative dispensing of blood components is required for clinical application in pediatric blood use, the flow stop clamp 12 on the dispensing tubing is closed, the folded core barrier 13 on the blood component storage bag is opened, the dispensing blood bag is placed on a scale, the flow stop clamp 12 on the dispensing tubing is opened, and the storage bag is gently pressed to allow the blood components to enter the dispensing blood bag through the dispensing tubing. After the required blood volume is reached, the flow stop clamp on the dispensing tubing is closed, and the dispensing blood bag is heat-sealed for clinical transfusion. The remaining blood component storage multi-unit blood bag is used for other clinical transfusion needs.

[0023] Although the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the present invention. Any person skilled in the art can make some modifications and improvements without departing from the spirit and scope of the present invention. Therefore, the scope of protection of the present invention shall be determined by the claims.

Claims

1. A leukocyte removal filtration system for children, comprising a blood collection bag (5), characterized in that, The top of the blood collection bag (5) is connected in sequence to the filtered blood bag (6), the transfer bag (8) and the red blood cell preservation solution bag (10) via a connecting conduit. A leukocyte-reducing filter (4) is provided between the blood collection bag (5) and the filtered blood bag (6). The filtered blood bag (6) is connected to the RBC dispensing blood bag (7) via a dispensing conduit. The transfer bag (8) is connected to the plasma dispensing blood bag (9) via a dispensing conduit.

2. The leukocyte removal filtration system for children as described in claim 1, characterized in that, The top of the blood collection bag (5) is connected to the sampling device (3) and the blood collection needle (1) through a three-way fitting (11). A needle-puncture protection device (2) is provided between the blood collection needle (1) and the three-way fitting (11). A flow stop clamp (12) is provided between the sampling device (3) and the blood collection bag (5).

3. The leukocyte removal filtration system for children as described in claim 2, characterized in that, The sampling device (3), blood collection bag (5), filtered blood bag (6), RBC dispensing blood bag (7), transfer bag (8), plasma dispensing blood bag (9), red blood cell preservation fluid bag (10) and connecting catheter are all made of BTHC-plasticized PVC material.

4. The leukocyte removal filtration system for children as described in claim 1, characterized in that, The dispensing conduit is equipped with a flow stop clamp (12).

5. The leukocyte removal filtration system for children as described in claim 1, characterized in that, The filtered blood bag (6) is provided with a transfusion port (14), and the transfusion port (14) is made of BTHC plasticized PVC material.

6. The leukocyte removal filtration system for children as described in claim 1, characterized in that, The blood collection bag (5), the filtered blood bag (6), the transfer bag (8) and the red blood cell preservation solution bag (10) are provided with a folded core barrier (13), and the folded core barrier (13) is made of PC material.

7. The leukocyte removal filtration system for children as described in claim 1, characterized in that, The outer shell of the leukocyte removal filter (4) is made of PC material, and the filter material of the leukocyte removal filter (4) is PBT non-woven fabric.

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