Blood purification using a recirculation line and a blood purification system

Abstract

The utility model discloses a kind of blood purification uses circulation pipeline, including artery pipe and vein pipe;Artery pipe is sequentially provided with blood pump pipe, arterial pot and first dialysis connector along blood flow direction;Parallel section and main pipe section are sequentially provided along blood flow direction between arterial pot and first dialysis connector;First dialysis connector is arranged at the end of main pipe section;First branch and second branch are sequentially provided on parallel section along blood flow direction, and the end of first branch and second branch is respectively provided with the first joint and second joint for connecting the main interface of the two ends of perfusion device;Vein pipe is sequentially provided with second dialysis connector and venous pot along blood flow direction;First dialysis connector and second dialysis connector are respectively used for being connected with the arterial interface and venous interface of dialyzer.The utility model further discloses a kind of blood purification system.The blood purification uses circulation pipeline and blood purification system of the utility model can realize that perfusion device and dialyzer are used in combination, and can effectively reduce connecting joint.

Description

Technical Field

[0001] This utility model belongs to the field of blood purification technology, specifically a blood purification circulation pipeline and blood purification system. Background Technology

[0002] A hemoperfusion device draws blood from the patient's body into the extracorporeal circulation system. The adsorbent (made of activated carbon, resin, etc.) within the device binds to and removes metabolic byproducts, toxic substances, and drugs from the body, thus achieving the desired therapeutic effect. In recent years, with the development and technological advancements of new hemoperfusion devices, their application has expanded beyond drug or toxin poisoning to include the rescue and treatment of severe infections, severe liver failure, end-stage renal disease (uremia), and various autoimmune diseases.

[0003] Hemodialysis combined with hemoperfusion (HD+HP) has become the most widely used combined artificial kidney treatment method in clinical practice. When connecting the tubing for combined treatment, the extracorporeal circulation tubing usually cannot be directly connected to the perfusion device; additional tubing is required. Adding additional tubing presents several problems, including:

[0004] (1) Adding connecting pipes will increase the number of connecting joints, which will increase the risk of poor sealing and increase the difficulty of use and operation. For example, if the joints are not tightened, it will lead to the risk of pipeline leakage.

[0005] (2) The connection and matching problems between the connecting pipes of different manufacturers and the extracorporeal circulation pipeline may lead to product leakage and pipe bursting risk in severe cases.

[0006] (3) Since the connecting tube and the pipeline are separate products, the treatment cost for patients is increased. Summary of the Invention

[0007] In view of this, the purpose of this utility model is to provide a blood purification circulation pipeline and blood purification system that is not only suitable for use in conjunction with an perfusion device and a dialyzer, but also effectively reduces the number of connection joints.

[0008] To achieve the above objectives, this utility model provides the following technical solution:

[0009] This utility model first proposes a blood purification circulatory system, including an arterial tube and a venous tube;

[0010] The arterial tube is provided with a blood pump tube, an arterial chamber, and a first dialysis connector in sequence along the blood flow direction; a parallel section and a main section are provided between the arterial chamber and the first dialysis connector in sequence along the blood flow direction; the first dialysis connector is located at the end of the main section; a first branch and a second branch are provided in sequence along the blood flow direction on the parallel section, and the ends of the first branch and the second branch are respectively provided with a first connector and a second connector for connecting the main interfaces at both ends of the perfusion device.

[0011] The vein tube is provided with a second dialysis connector and a vein chamber in sequence along the direction of blood flow;

[0012] The first dialysis connector and the second dialysis connector are used to connect to the arterial interface and the venous interface of the dialyzer, respectively.

[0013] Furthermore, the first branch and the second branch are respectively provided with a first branch switch clamp and a second branch switch clamp; the parallel section is provided with a first switch clamp.

[0014] Furthermore, it also includes a third branch, which is connected to the second branch or the main pipe section, and the end of the third branch is provided with a third connector for connecting a waste liquid bag.

[0015] Furthermore, a third branch switch clamp is provided on the third branch, and a second switch clamp located on the second branch or the main pipe section is provided between the third branch and the first dialysis connector.

[0016] Furthermore, it also includes a fourth branch, which is connected to the second branch or the parallel section, and the end of the fourth branch is provided with a fourth connector for connecting to a multi-functional interface located at one end of the irrigation device.

[0017] Furthermore, the third branch is located between the fourth branch and the first dialysis connector.

[0018] Furthermore, a fourth branch switch clamp is provided on the fourth branch.

[0019] Furthermore, it also includes a fifth branch, which is connected to the fourth branch or a parallel section, and the end of the fifth branch is provided with a fifth connector for connecting to a multi-functional interface located at the other end of the irrigation device.

[0020] Furthermore, a fifth branch switch clamp is provided on the fifth branch.

[0021] Furthermore, an auxiliary branch is provided on the first branch, and an auxiliary connector is provided at the end of the auxiliary branch. A third switch clamp is provided on the auxiliary branch.

[0022] This utility model also proposes a blood purification system, including an perfusion device, a dialyzer, and a blood purification circulation pipeline as described above. The perfusion device has a main interface at both ends, and the dialyzer has an arterial interface and a venous interface at both ends. The first branch and the second branch are respectively connected to the main interfaces at both ends of the perfusion device through the first connector and the second connector. The first dialysis connector and the second dialysis connector are respectively connected to the arterial interface and the venous interface of the dialyzer.

[0023] The beneficial effects of this utility model are as follows:

[0024] This invention utilizes a circulating tubing for blood purification. By installing a first dialysis connector and a second dialysis connector on the arterial and venous tubing respectively, it can be directly connected to the arterial and venous interfaces of the dialyzer. Furthermore, by establishing a parallel section between the arterial chamber and the first dialysis connector support, and by providing a first branch and a second branch on this parallel section for connection to the perfusion device, it becomes suitable for applications where the perfusion device and dialyzer are used together. Moreover, by integrating the first and second branches directly with the arterial tubing, the number of connection connectors is effectively reduced, lowering the risk of poor sealing and operational difficulty, and improving safety performance. Attached Figure Description

[0025] To make the objectives, technical solutions, and beneficial effects of this utility model clearer, the following drawings are provided for illustration:

[0026] Figure 1 This is a schematic diagram of the blood purification system of this utility model, specifically a schematic diagram of the structure when the third branch is connected to the second branch;

[0027] Figure 2 This is a schematic diagram of the structure when the third branch of the blood purification system is connected to the main branch in this embodiment;

[0028] Figure 3 This is a schematic diagram of the blood purification system in this embodiment when a fourth branch is provided and both the third and fourth branches are connected to the second branch;

[0029] Figure 4 This is a schematic diagram of the blood purification system in this embodiment when a fourth branch is provided and the third branch is connected to the main branch.

[0030] Figure 5 This is a schematic diagram of the blood purification system in this embodiment when a fifth branch is provided and the fifth branch is connected to the second branch.

[0031] Figure 6 This is a schematic diagram of the blood purification system in this embodiment when a fifth branch is provided and the third branch is connected to the main branch;

[0032] Figure 7 This is a structural view of the blood purification system in this embodiment when a fifth branch is provided and the fifth branch is connected to the parallel section;

[0033] Figure 8 This is a structural view of the blood purification system in this embodiment when a fourth branch is provided and the fourth branch is connected to the parallel section;

[0034] Figure 9 This is a schematic diagram of the blood purification system in this embodiment when an auxiliary branch is provided.

[0035] Explanation of reference numerals in the attached figures:

[0036] 1-Perfusion device; 2-Dialyzer; 3-Waste liquid bag;

[0037] 10-Arterial tube; 11-Blood pump tube; 12-Arterial chamber; 13-First dialysis connector; 14-Parallel section; 141-First switch clamp; 15-Main tube section; 16-First branch; 161-First connector; 162-First branch switch clamp; 17-Second branch; 171-Second connector; 172-Second branch switch clamp; 18-Third branch; 19-Second switch clamp; 20-Fourth branch; 201-Fourth connector; 202-Fourth branch switch clamp; 21-Fifth branch; 211-Fifth connector; 212-Fifth branch switch clamp; 22-Anticoagulant branch; 23-Auxiliary branch; 231-Auxiliary connector; 232-Third switch clamp;

[0038] 30-Vein tube; 31-Second dialysis connector; 32-Vein chamber. Detailed Implementation

[0039] The present invention will be further described below with reference to the accompanying drawings and specific embodiments, so that those skilled in the art can better understand and implement the present invention. However, the embodiments are not intended to limit the present invention.

[0040] like Figure 1-2 As shown, the blood purification system of this embodiment includes an perfusion device 1, a dialyzer 2, and a blood purification circulation pipeline. The perfusion device 1 has a main interface at both ends, and the dialyzer 2 has an arterial interface and a venous interface at both ends.

[0041] This embodiment of blood purification uses a circulatory system, including an arterial tube 10 and a venous tube 30. Specifically, the arterial tube 10 is provided with a blood pump tube 11, an arterial chamber 12, and a first dialysis connector 13 sequentially along the blood flow direction. A parallel section 14 and a main tube section 15 are sequentially provided between the arterial chamber 12 and the first dialysis connector 13 along the blood flow direction. An anticoagulant branch 22 is provided at the inlet side of the blood pump tube 11 or between the blood pump tube 11 and the arterial chamber 12. The first dialysis connector 13 is located at the end of the main tube section 15. A first branch 16 and a second branch 17 are sequentially provided along the blood flow direction on the parallel section 14, and the ends of the first branch 16 and the second branch 17 are respectively provided with a first connector 161 and a second connector 171 for connecting the main interfaces at both ends of the perfusion device 1. The venous tube 30 is provided with a second dialysis connector 31 and a venous chamber 32 sequentially along the blood flow direction.

[0042] In this embodiment, the first branch 16 and the second branch 17 are connected to the main interfaces at both ends of the perfusion device 1 via the first connector 161 and the second connector 171, respectively. The first dialysis connector 13 and the second dialysis connector 31 are connected to the arterial interface and the venous interface of the dialyzer 2, respectively.

[0043] In this embodiment, the first branch 16 and the second branch 17 are respectively provided with a first branch switch clamp 162 and a second branch switch clamp 172. The parallel section 14 is provided with a first switch clamp 141. Thus, when the perfusion device 1 and the dialyzer 2 need to be used together, the first switch clamp 141 is closed, and the first branch switch clamp 162 and the second branch switch clamp 172 are opened, so that blood flows through the arterial tube 10 through the perfusion device 1 and the dialyzer 2, and then returns from the venous tube 30; when the perfusion device 1 is saturated or only the dialyzer 2 is needed for treatment, the first branch switch clamp 162 and the second branch switch clamp 172 are closed, and the first switch clamp 141 is opened, so that blood flows through the arterial tube 10 through the parallel section 14 and the dialyzer 2, and then returns from the venous tube 30.

[0044] In a preferred embodiment of this example, such as Figure 1-2 As shown, the blood purification circulation pipeline in this embodiment also includes a third branch 18, which is connected to the second branch 17 or the main pipe section 15. The end of the third branch 18 is provided with a third connector for connecting the waste liquid bag 3. Figure 1 The diagram shown is a structural schematic of the connection between the third branch 18 and the second branch 17; as shown... Figure 2 The diagram shows the structural connection between the third branch 18 and the main pipe section 15. Specifically, to control the flow direction, the third branch 18 in this embodiment is equipped with a third branch switch clip, and a second switch clip 19 located on the second branch 17 or the main pipe section 15 is provided between the third branch 18 and the first dialysis connector 13. Figure 1 As shown, the second switch clip 19 is disposed on the second branch 17 and located between the parallel section 14 and the first dialysis connector 13. Figure 2 As shown, the second switch clip 19 is disposed on the main pipe section 15 and located between the third branch 18 and the first dialysis connector 13.

[0045] like Figure 3-8 As shown, in one embodiment of this invention, the blood purification circulation tubing further includes a fourth branch 20, which is connected to the second branch 17 or the parallel section 14. The end of the fourth branch 20 is provided with a fourth connector 201 for connection to a multi-functional interface located at one end of the perfusion device 1. Figure 3 The diagram shown illustrates the connection between the fourth branch 20 and the second branch 17. Figure 4 The diagram shows the structure connecting the fourth branch 20 to the parallel section 14. When pre-filling the perfusion device 1, the fourth branch 20 is required to be connected to the waste bag 3; therefore, the third branch 18 is located between the fourth branch 20 and the first dialysis connector 13. Specifically, when the third branch 18 is connected to the second branch 17, the fourth branch 20 is required to be connected to the second branch 17; when the third branch 18 is connected to the main pipe section 15, the fourth branch 20 can be connected to the second branch 17, and the fourth branch 20 can also be connected to the parallel section 14. To control the flow direction, the fourth branch 20 in this embodiment is equipped with a fourth branch switch clip 202. Depending on the needs, the multi-functional interface can be used for pre-filling and venting, blood sampling during treatment, drug administration, or fluid infusion during blood return operations on the perfusion device 1.

[0046] Specifically, with the fourth branch 20 installed, the perfusion device 1 can be pre-charged individually. When pre-charging the perfusion device 1 individually, the first switch clamp 141, the second switch clamp 19, and the second branch switch clamp 172 need to be closed, while the first branch switch clamp 162, the third branch switch clamp, and the fourth branch switch clamp 202 need to be opened. When the perfusion device 1 needs to be used in conjunction with the dialyzer 2, the first switch clamp 141, the third branch switch clamp, and the fourth branch switch clamp 202 need to be closed, while the first branch switch clamp 162, the second branch switch clamp 172, and the second switch clamp 19 need to be opened, allowing blood to flow through the arterial tube 10 through the perfusion device 1 and the dialyzer 2. Blood returns from the venous tube 30; when the perfusion device 1 is saturated or only the dialyzer 2 is needed for treatment, the first branch switch clamp 162, the second branch switch clamp 172, the third branch switch clamp and the fourth branch switch clamp 202 are closed, and the first switch clamp 141 is opened; and: when the second switch clamp 19 is on the main line 15, the second switch clamp 19 is opened; when the second switch clamp 19 is on the second branch 17, the second switch clamp 19 does not need to be opened; allowing blood to flow through the arterial tube 10, through the parallel section 14 and the dialyzer 2, and then return from the venous tube 30.

[0047] like Figure 5-8As shown, in one embodiment of this invention, the blood purification circulation tubing further includes a fifth branch 21, which is connected to the fourth branch 20 or the parallel section 14. The end of the fifth branch 21 is provided with a fifth connector 211 for connection to a multi-functional interface located at the other end of the perfusion device 1. Figure 5-6 The diagram shown illustrates the connection between the fifth branch 21 and the fourth branch 20. Figure 7-8 The diagram shows the connection between the fifth branch 21 and the parallel section 14. Similarly, in order to control the flow direction, the fifth branch 21 is equipped with a fifth branch switch clamp 212.

[0048] Specifically, with the fifth branch 21 installed, the perfusion device 1 can be pre-charged individually. When pre-charging the perfusion device 1 individually, the first switch clamp 141, the second switch clamp 19, and the second branch switch clamp 172 need to be closed, while the first branch switch clamp 162, the third branch switch clamp, the fourth branch switch clamp 202, and the fifth branch switch clamp 212 need to be opened. When the perfusion device 1 needs to be used in conjunction with the dialyzer 2, the first switch clamp 141, the third branch switch clamp, the fourth branch switch clamp 202, and the fifth branch switch clamp 212 need to be closed, while the first branch switch clamp 162, the second branch switch clamp 172, and the second switch clamp 19 need to be opened, allowing blood to flow through the arterial tube 10 through the perfusion device 1 and the dialyzer 2. After dialyzer 2, blood returns from the venous tube 30. When the perfusion device 1 is saturated or only dialyzer 2 is needed for treatment, the first branch switch clamp 162, the second branch switch clamp 172, the third branch switch clamp, the fourth branch switch clamp 202, and the fifth branch switch clamp 212 are closed, and the first switch clamp 141 is opened. Also: when the second switch clamp 19 is on the main line 15, the second switch clamp 19 is opened; when the second switch clamp 19 is on the second branch 17, the second switch clamp 19 does not need to be opened. This allows blood to flow through the arterial tube 10, through the parallel section 14, and the dialyzer 2, and then return from the venous tube 30.

[0049] In a preferred embodiment of this example, the first branch 16 is provided with an auxiliary branch 23, the end of the auxiliary branch 23 is provided with an auxiliary connector 231, and the auxiliary branch 23 is provided with a third switch clip 232, such as... Figure 9 The auxiliary branch 23 can be used to add medicine to the perfusion device 1, or after the perfusion device 1 reaches the treatment time (perfusion device 1 is saturated), saline can be injected into the perfusion device 1 through the auxiliary branch 23 to drain the blood in the perfusion device 1 (i.e., blood return).

[0050] The above-described embodiments are merely preferred embodiments provided to fully illustrate the present invention, and the scope of protection of the present invention is not limited thereto. Equivalent substitutions or modifications made by those skilled in the art based on the present invention are all within the scope of protection of the present invention. The scope of protection of the present invention is defined by the claims.

Claims

1. A blood purification circulation tubing system, characterized in that: Including arterial and venous vessels; The arterial tube is provided with a blood pump tube, an arterial chamber, and a first dialysis connector in sequence along the blood flow direction; a parallel section and a main section are provided between the arterial chamber and the first dialysis connector in sequence along the blood flow direction; the first dialysis connector is located at the end of the main section; a first branch and a second branch are provided in sequence along the blood flow direction on the parallel section, and the ends of the first branch and the second branch are respectively provided with a first connector and a second connector for connecting the main interfaces at both ends of the perfusion device. The vein tube is provided with a second dialysis connector and a vein chamber in sequence along the direction of blood flow; The first dialysis connector and the second dialysis connector are used to connect to the arterial interface and the venous interface of the dialyzer, respectively.

2. The blood purification circulation tubing according to claim 1, characterized in that: The first branch and the second branch are respectively provided with a first branch switch clamp and a second branch switch clamp; the parallel section is provided with a first switch clamp.

3. The blood purification circulation tubing according to claim 1 or 2, characterized in that: It also includes a third branch, which is connected to the second branch or the main pipe section, and the end of the third branch is provided with a third connector for connecting a waste liquid bag.

4. The blood purification system using a circulation tubing according to claim 3, characterized in that: A third branch switch clamp is provided on the third branch, and a second switch clamp located on the second branch or the main pipe is provided between the third branch and the first dialysis connector.

5. The blood purification circulation tubing according to claim 3, characterized in that: It also includes a fourth branch, which is connected to the second branch or the parallel section, and the end of the fourth branch is provided with a fourth connector for connecting to a multi-functional interface located at one end of the perfusion device; the third branch is located between the fourth branch and the first dialysis connector.

6. The blood purification circulation tubing according to claim 5, characterized in that: The fourth branch is equipped with a fourth branch switch clamp.

7. The blood purification circulation tubing according to claim 5, characterized in that: It also includes a fifth branch, which is connected to the fourth branch or a parallel section, and the end of the fifth branch is provided with a fifth connector for connecting to a multi-functional interface located at the other end of the irrigation device.

8. The blood purification circulation tubing according to claim 7, characterized in that: The fifth branch is equipped with a fifth branch switch clamp.

9. The blood purification circulation tubing according to claim 1, characterized in that: An auxiliary branch is provided on the first branch, and an auxiliary connector is provided at the end of the auxiliary branch. A third switch clamp is provided on the auxiliary branch.

10. A blood purification system, characterized in that: The device includes an perfusion device, a dialyzer, and a blood purification circulation tubing as described in any one of claims 1-9. The perfusion device has a main interface at both ends, and the dialyzer has an arterial interface and a venous interface at both ends. The first branch and the second branch are connected to the main interfaces at both ends of the perfusion device through the first connector and the second connector, respectively. The first dialysis connector and the second dialysis connector are connected to the arterial interface and the venous interface of the dialyzer, respectively.

Images