Filtering device for tylosin decolorization

Abstract

The utility model discloses a tylosin decolorization is with filter device belongs to the biopharmaceutical equipment technical field, including decoloring jar, desolventizing jar and candle type filter, and the import of candle type filter is connected with the export of decoloring jar through feed line, and the export of candle type filter is connected with the import of desolventizing jar through discharge line, and the discharge line is communicated with the return line, and one end of return line is connected on the discharge line, and the other end is connected to the import of decoloring jar, and the feed line is equipped with feed valve, and the discharge line is equipped with discharge valve, and the return line is equipped with return valve. Through setting up candle type filter and return line, cooperate with the closed circulation passageway formed by feed valve, discharge valve and return valve, ensure that only the liquid that reaches the predetermined clarification standard can be sent into desolventizing jar, avoid the risk of tylosin liquid turbidity exceeding the standard caused by single filtration effect, significantly improve the clarity and quality stability of tylosin finished material, reduce the labor intensity.

Description

Technical fields: This utility model belongs to the field of biopharmaceutical equipment technology, and more specifically relates to a filtration device for tylosin decolorization. Background technology: During the production of tylosin, granular activated carbon is used to remove impurities such as pigments from the feed solution. After adsorption, the activated carbon needs to be removed. Currently, plate filters are commonly used for activated carbon removal. This equipment requires the use of both twill filter cloth and fine cloth in production. Therefore, during production, there are two main problems: First, the filtration effect of plate filters is not good, which can easily lead to excessive turbidity in the tylosin feed solution. In addition, the filter cloth needs to be cleaned and installed daily, requiring two people to work together, resulting in a heavy workload for operators. Second, the filter cloth replacement cycle is relatively short, and the disposal of waste filter cloth requires additional environmental protection costs, increasing production costs. Utility Model Content: To solve the above problems and overcome the shortcomings of the prior art, this utility model provides a filtration device for tylosin decolorization; The first technical problem to be solved was that the plate filter had poor filtration effect, which could easily lead to excessive turbidity in the Tylosin solution, requiring daily cleaning and installation of the filter cloth, which was labor-intensive.

[0004] The second technical problem to be solved is that the filter cloth replacement cycle is relatively short, and the disposal of waste filter cloth requires additional environmental protection costs, which increases production costs.

[0005] The specific technical solution of this utility model to solve the above-mentioned technical problems is as follows: the filtration device for decolorizing tylosin includes a decolorizing tank and a desolvation tank, and also includes a candle filter for filtering activated carbon in tylosin solution. The inlet of the candle filter is connected to the outlet of the decolorizing tank through a feed pipe, and the outlet of the candle filter is connected to the inlet of the desolvation tank through a discharge pipe. A return pipe is connected to the discharge pipe, one end of which is connected to the discharge pipe and the other end is connected to the inlet of the decolorization tank. The feed pipe is equipped with a feed valve, the discharge pipe is equipped with a discharge valve, and the return pipe is equipped with a return valve.

[0006] Furthermore, the bottom of the candle filter is provided with a material collection trough, the material collection trough is connected to a bottom discharge valve, and below the bottom discharge valve is an interface structure for sealing connection with the inlet of the ton bag.

[0007] Furthermore, the candle filter is provided with a backflush line, one end of which is connected to the high-pressure air source, and the other end is connected to the top inlet of the candle filter or directly to the inside of the candle filter housing. A backflush valve is provided on the backflush line.

[0008] Furthermore, the top of the candle filter is provided with a top wash water pipeline, one end of which is connected to the purified water source and the other end is connected to the inlet of the candle filter. A top wash water valve is provided on the top wash water pipeline.

[0009] Furthermore, the candle filter is also provided with a rinsing water pipe for rinsing the inside of the candle filter, and a rinsing water valve is installed on the rinsing water pipe.

[0010] The beneficial effects of this utility model are: One advantage of this invention is that by setting up a candle filter and a reflux pipeline, along with a closed-loop circulation path consisting of a feed valve, a discharge valve, and a reflux valve, it ensures that only the liquid that meets the predetermined clarification standard is sent to the desolvation tank. This avoids the risk of excessive turbidity in the tylosin liquid due to poor single-pass filtration, significantly improves the clarity and quality stability of the finished tylosin product, and reduces labor intensity.

[0011] One advantage of this invention is that the candle filter has a rinsing device at the top inside, which can perform in-situ and comprehensive rinsing of the filter bag, flushing out the fine impurities attached deep to the filter bag, extending the service life of the filter bag and reducing consumable costs.

[0012] One advantage of this invention is that it provides a top wash water pipeline that is directly connected to the inlet of the candle filter and controls the flow direction through a valve. This ensures that the residual liquid can be recovered to the desolvation tank through the pipeline connection. For high-value antibiotic products, this structure can quantitatively recover several liters or even tens of liters of residual liquid in each batch of the filtration system and directly convert it into product output, resulting in significant economic benefits. Attached image description: Appendix Figure 1 This is a schematic diagram of the structure of this utility model; in the attached drawing: 1. Decolorization tank; 2. Desolventizing tank; 3. Candle filter; 31. Collection trough; 32. Bottom discharge valve; 4. Feeding pipeline; 41. Feeding valve; 5. Discharge pipeline; 51. Discharge valve; 6. Return pipeline; 61. Return valve; 7. Backflush pipeline; 71. Backflush valve; 8. Top wash water pipeline; 81. Top wash water valve; 9. Rinse water pipeline; 91. Rinse water valve. Detailed implementation method: In the description of this utility model, it should be understood that the terms "center," "upper," "lower," "left," "right," "rear," "lower left," "upper right," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limiting the scope of protection of this utility model. In addition, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0015] The specific embodiment of this utility model is as follows: A filtration device for decolorizing tylosin includes a decolorizing tank 1 and a desolvation tank 2, and further includes a candle filter 3 for filtering activated carbon in the tylosin solution. The inlet of the candle filter 3 is connected to the outlet of the decolorizing tank 1 through a feed pipe 4, and the outlet of the candle filter 3 is connected to the inlet of the desolvation tank 2 through a discharge pipe 5. A return pipe 6 is connected to the discharge pipe 5, one end of the return pipe 6 is connected to the discharge pipe 5, and the other end is connected to the inlet of the decolorizing tank 1. A feed valve 41 is provided on the feed pipe 4, a discharge valve 51 is provided on the discharge pipe 5, and a return valve 61 is provided on the return pipe 6.

[0016] This structure, by setting up a candle filter 3 and a return pipeline 6, along with a closed-loop circulation path consisting of a feed valve 41, a discharge valve 51, and a return valve 61, ensures that only the liquid that meets the predetermined clarification standard is sent into the desolvation tank 2. This avoids the risk of excessive turbidity in the tylosin liquid due to poor single filtration effect, and significantly improves the clarity and quality stability of the finished tylosin product.

[0017] Preferably, the bottom of the candle filter 3 is provided with a material collection trough 31, which is funnel-shaped, and a bottom discharge valve 32 is provided at the bottom of the material collection trough 31.

[0018] Preferably, the candle filter 3 is provided with a backflush pipe 7, one end of which is connected to the high-pressure air source, and the other end is connected to the feed pipe 4 and extends into the interior of the candle filter 3. A backflush valve 71 is provided on the backflush pipe 7.

[0019] Preferably, the top of the candle filter 3 is provided with a top wash water pipe 8, one end of which is connected to the purified water source and the other end is connected to the feed pipe 4, extending into the interior of the candle filter 3. A top wash water valve 81 is provided on the top wash water pipe 8.

[0020] Preferably, the candle filter 3 is further provided with a rinsing water pipe 9 for rinsing the inside of the candle filter 3. One end of the rinsing water pipe 9 is connected to a cleaning water source, and the other end extends into the inside of the candle filter 3. The end of the rinsing water pipe 9 is provided with multiple fan-shaped nozzles, which are evenly arranged circumferentially on the top of the filter to spray and cover the surface of the filter bag inside the candle filter 3. The working principle and structure of the fan-shaped nozzles spraying the surface of the filter bag are existing technologies and are not included in the protection scope of this utility model, so they will not be described in detail here. A rinsing water valve 91 is provided on the rinsing water pipe 9.

[0021] It should be noted that this utility model is a filtration device for tylosin decolorization. In specific operation... The tylosin decolorizing solution to be treated flows out of the decolorization tank 1. By opening the inlet valve 41 and the reflux valve 61, while simultaneously closing the outlet valve 51 leading to the desolvation tank 2, the solution enters the candle filter 3 through the inlet pipe 4. The solution penetrates the filter bag inside the candle filter 3, and the activated carbon is trapped to form a waste carbon filter cake. The filtrate flows out from the top outlet pipe 5 and returns entirely to the decolorization tank 1 through the reflux pipe 6. This process utilizes the closed-loop circulation path formed by the reflux pipe 6 and the inlet valve 41, outlet valve 51, and reflux valve 61. As the tylosin decolorizing solution circulates within the system, the waste carbon filter cake layer in the candle filter 3 gradually forms and becomes denser, resulting in increasingly higher retention efficiency for fine carbon particles.

[0022] After the reflux liquid clarifies, close the reflux valve 61 and open the discharge valve 51 leading to the desolvation tank 2. The clarified tylosin decolorized liquid is then directly transported to the desolvation tank 2 for further processing. After the liquid transport is complete, open the top wash water valve 81, and purified water enters the candle filter 3, pushing out the high-value tylosin liquid remaining in the filter housing and waste carbon filter cake. The top wash water pipeline 8 is directly connected to the inlet of the candle filter 3, and the flow direction of the top wash water is the same as that of the liquid, ultimately entering the desolvation tank 2. For high-value antibiotic products, this structure can quantitatively recover several liters or even tens of liters of liquid remaining in the filtration system from each batch, directly converting it into product output, resulting in significant economic benefits.

[0023] After the top wash is completed, the top wash water valve 81 and the discharge valve 51 are closed, and the high-pressure air backflush valve 71 is opened. High-pressure gas enters the top of the candle filter 3, penetrates the waste carbon filter cake, squeezes out the residual moisture, and dries the waste carbon filter cake. Then, the bottom discharge valve 32 is opened and the backflush valve 71 is maintained. The high-pressure air source and backflush pipeline 7 provide gas power. The gas pressure causes the filter bag to expand and deform slightly, and the waste carbon filter cake breaks and falls off the surface of the filter bag. The waste carbon filter cake is dried and shaken off by compressed air, falling into the collection trough 31 and discharged through the bottom discharge valve 32. At this time, the waste carbon filter cake discharged from the bottom discharge valve 32 can be collected manually using a ton bag used to collect the waste carbon filter cake. This structure achieves zero dust leakage throughout the process, meets the cleanliness requirements of pharmaceutical manufacturing quality management standards for raw material production, and protects the operating environment and employee health.

[0024] After the waste carbon filter cake is unloaded, close the bottom unloading valve 32 and the backflush valve 71. Open the rinsing water valve 91, and the rinsing water is delivered through the rinsing water pipe 9 to the inside of the candle filter 3. The water is then sprayed evenly around the outer surface of all the filter bags through the nozzles inside the candle filter 3, so that the filter bags can be rinsed in situ and thoroughly. This washes out the fine impurities attached deep to the filter bags, extends the service life of the filter bags, and reduces consumable costs.

[0025] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claims. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A filtration device for tylosin decolorization, comprising a decolorization tank (1) and a desolvation tank (2), characterized in that, It also includes a candle filter (3) for filtering activated carbon in tylosin solution. The inlet of the candle filter (3) is connected to the outlet of the decolorizing tank (1) through the feed pipe (4), and the outlet of the candle filter (3) is connected to the inlet of the desolvation tank (2) through the discharge pipe (5). The discharge pipe (5) is connected to a return pipe (6), one end of the return pipe (6) is connected to the discharge pipe (5), and the other end is connected to the inlet of the decolorizing tank (1); The feed pipe (4) is equipped with a feed valve (41), the discharge pipe (5) is equipped with a discharge valve (51), and the return pipe (6) is equipped with a return valve (61).

2. The filtration device for tylosin decolorization according to claim 1, characterized in that, The bottom of the candle filter (3) is provided with a material collection trough (31), and the bottom of the material collection trough (31) is connected to a bottom discharge valve (32).

3. The filtration device for tylosin decolorization according to claim 1, characterized in that... The candle filter (3) is provided with a backflush pipe (7). One end of the backflush pipe (7) is connected to a high-pressure gas source, and the other end is connected to the inlet of the candle filter (3) or directly connected to the inside of the housing of the candle filter (3). A backflush valve (71) is provided on the backflush pipe (7).

4. The filtration device for tylosin decolorization according to claim 1, characterized in that, The top of the candle filter (3) is provided with a top wash water pipe (8), one end of which is connected to the purified water source and the other end is connected to the inlet of the candle filter (3). A top wash water valve (81) is provided on the top wash water pipe (8).

5. The filtration device for tylosin decolorization according to claim 1, characterized in that, The candle filter (3) is also provided with a rinsing water pipe (9) for rinsing the inside of the candle filter (3), and a rinsing water valve (91) is provided on the rinsing water pipe (9).

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