A high-pressure dead-end constant-flow separation membrane performance testing device

Abstract

The utility model belongs to but is not limited to the separation membrane performance test technical field, disclose a kind of high-pressure dead-end constant current separation membrane performance test equipment, solve the problem such as existing equipment high-pressure test deficiency, large constant voltage error, material liquid consumption more etc..Equipment includes metal shell and the high-pressure plunger infusion pump of integration / fixed on it, miniature cylindrical diaphragm filter container, pressure monitoring recording unit, magnetic stirrer and constant temperature water bath device.Provide >60bar pressure, 0.01mL / min flow rate precision and constant current control for high-pressure plunger infusion pump;Miniature container 12mL, adaptation 3cm diaphragm, outside 5-95 ℃±0.5 ℃ constant temperature water bath of temperature control, below magnetic stirrer;Pressure monitoring unit contains 0.01bar precision sensor and 1Hz sampling paperless recorder.Equipment area is less than 0.3m², adaptation high-pressure membrane test, improve data precision, reduce cost, realize accurate and efficient test.

Description

Technical Field

[0001] This utility model belongs to, but is not limited to, the field of separation membrane performance testing technology, and particularly relates to a high-voltage dead-end constant current separation membrane performance testing device. Background Technology

[0002] Membrane separation technology is a core technology in water treatment, material separation, and other fields, and accurate performance testing is a key prerequisite for membrane material research and development and process optimization. Currently, commonly used membrane separation testing systems mainly include low-pressure dead-end filtration systems and low-pressure and high-pressure cross-flow filtration systems.

[0003] Low-pressure dead-end filtration uses high-pressure gas cylinders, typically nitrogen cylinders, to provide pressure. Membrane testing containers can generally withstand pressures not exceeding 6 bar, limiting the testing range and making it impossible to test high-pressure nanofiltration membranes and reverse osmosis membranes. High-pressure gas cylinders also occupy a large space and pose safety hazards.

[0004] While cross-flow filtration systems can provide different pressures by selecting different pump types, they also have several problems: high-speed flow causes pressure fluctuations and errors; they require a large dead volume in the pipeline, and performance testing requires a large amount of feed liquid; the pipeline flushing process is cumbersome; high-pressure pump cross-flow filtration systems occupy a large space; and the membrane installation process is cumbersome.

[0005] Furthermore, both of the above devices are currently tested under constant pressure, which means that the principle remains constant, but the membrane permeation flow rate cannot be adjusted. The membrane permeation flux directly affects the concentration polarization phenomenon in the membrane separation process, thereby affecting indicators such as membrane rejection and membrane fouling. In other words, the constant pressure process cannot eliminate the difference in rejection rate caused by different flux by controlling variables, which to some extent reduces the accuracy of the evaluation of the separation performance of the separation membrane itself.

[0006] Existing technology 1 (CN 102049199 B): It uses nitrogen cylinders for pressure supply (constant pressure mode), the permeation tank is a large-area submerged structure, there is no constant flow control function, and the stirring device is only used for mixing the feed liquid, which cannot specifically weaken the concentration polarization of the membrane surface.

[0007] Existing technology 2 (CN 206553337 U): The separation membrane has no high-pressure adapter design, the air pump and the separation membrane are independent modules, the stirring device is used to mix acetic acid and reducing agent, and it does not have the core function of membrane performance testing.

[0008] Existing technology limitations: Low-pressure dead-end systems with pressure ≤6 bar cannot test high-pressure nanofiltration / reverse osmosis membranes; high-pressure gas cylinders are bulky and pose safety hazards. Constant-pressure testing cannot control the flow rate, and flux differences lead to errors in rejection rates. Cross-flow systems require large-volume tubing (>100 mL) and feed solution, resulting in high costs. Cross-flow system tubing flushing is cumbersome, and membrane installation is complex. Traditional systems only display static pressure values ​​and cannot capture fluctuation details. High-pressure gas cylinders require regular safety inspections, and cross-flow pump valves are prone to wear.

[0009] In summary, existing technologies cannot simultaneously meet the requirements of "high-pressure testing", "constant current speed control", "low power consumption and high efficiency" and "integrated operation", and there is an urgent need for a separation membrane performance testing device that can fill this gap. Utility Model Content

[0010] To address the problems existing in the prior art, this utility model provides a high-pressure dead-end constant current separation membrane performance testing device, which realizes accurate constant current testing under high-pressure conditions, while reducing experimental costs and operational complexity.

[0011] This utility model is implemented as follows: a high-pressure dead-end constant current separation membrane performance testing device includes a metal shell and a high-pressure plunger infusion pump, a micro cylindrical membrane filter container, a pressure monitoring and recording unit, a magnetic stirrer, and a constant temperature water bath device integrated in or fixed to the metal shell platform.

[0012] The input end of the high-pressure plunger infusion pump is connected to the feed bottle, and the output end is connected to the micro cylindrical membrane filter container through a 1 / 16 liquid chromatography line. The high-pressure plunger infusion pump can provide a liquid pressure of >60 bar, and the flow rate control accuracy is up to 0.01 mL / min and supports constant flow closed-loop control.

[0013] The volume of the micro cylindrical membrane filter container is 12 mL, the diameter of the compatible membrane is 3 cm, the constant temperature water bath device is sleeved on the outside of the micro cylindrical membrane filter container, and the magnetic stirrer is located directly below the micro cylindrical membrane filter container, which can drive the magnetic rotor inside the container to rotate.

[0014] The pressure monitoring and recording unit includes a pressure sensor and a paperless recorder. The pressure sensor is connected in series in the pipeline between the high-pressure plunger infusion pump and the miniature cylindrical membrane filter container, with a measurement accuracy of 0.01 bar. The paperless recorder is electrically connected to the pressure sensor.

[0015] Furthermore, the high-pressure plunger infusion pump uses a corrosion-resistant ceramic plunger with a service life of >5000 hours.

[0016] Furthermore, the micro cylindrical membrane filter container includes a stainless steel upper cover, a stainless steel lower cover, a magnetic rotor, a magnetic stirring rod, a screw plug, a chromatography tubing connector, and a porous foam metal gasket; the porous foam metal gasket is disposed inside the stainless steel lower cover, the membrane to be tested is placed on the porous foam metal gasket, the stainless steel upper cover and the stainless steel lower cover are fastened and sealed by the hand-tightening screw, and the chromatography tubing connector is disposed at the corresponding interface of the stainless steel upper cover and the lower cover, and is adapted to the 1 / 16 liquid chromatography tubing.

[0017] Furthermore, the paperless recorder has a sampling frequency of 1Hz, can generate continuous pressure curves in real time, and automatically stores the pressure data as a CSV format file.

[0018] Furthermore, the temperature control range of the constant temperature water bath device is 5-95℃, and the temperature control accuracy is ±0.5℃. The bottom area of ​​the container of the constant temperature water bath device is similar to that of the bottom area of ​​the magnetic stirrer, and the height is consistent with the height of the micro cylindrical membrane filter container.

[0019] Furthermore, the metal casing is equipped with a modular mounting bracket inside for fixing the high-pressure plunger infusion pump and the paperless recorder; the overall footprint of the metal casing is <0.3m², and the external platform is used to place the miniature cylindrical membrane filter container, the magnetic stirrer, and the constant temperature water bath device.

[0020] Based on the above technical solutions and the technical problems solved, the advantages and positive effects of the technical solution to be protected by this utility model are as follows:

[0021] First, this utility model achieves accurate constant current testing at high-voltage dead ends while comprehensively addressing the shortcomings of traditional equipment, balancing low power consumption, high efficiency, and safety. Specifically, it is reflected in:

[0022] (1) Breakthrough in high-pressure testing capability and improved safety: The high-pressure plunger pump directly outputs liquid pressure >60 bar without relying on high-pressure gas cylinders, which is suitable for the testing requirements of high-pressure nanofiltration membranes and reverse osmosis membranes, and avoids the large footprint of gas cylinders (equipment volume is reduced by more than 50%) and the risk of gas leakage; the pump body uses corrosion-resistant ceramic plungers with a service life of >5000 hours, and the equipment failure rate is reduced by 80% (based on 3 months of trial operation data in the laboratory), reducing maintenance costs.

[0023] (2) Constant flow control eliminates flux interference and significantly improves data accuracy: The constant flow closed-loop feedback of the pump adjusts the plunger frequency and compensates for pressure fluctuations in real time. The flow rate control accuracy reaches 0.01 mL / min, so that the membrane flux is fixed at the set value. The concentration polarization effect is only related to the membrane performance itself. The coefficient of variation (CV value) of experimental data is reduced from ±15% in the traditional constant pressure mode to ±2%, while reducing the debugging time by 90% (without needing to repeatedly adjust the pressure to approach the target flux).

[0024] (3) Miniaturized design significantly reduces experimental costs: The 12mL miniature cylindrical dead-end filter chamber is compatible with a 3cm diameter membrane (effective membrane area 7cm²), reducing the amount of liquid used by 90% compared to the traditional cross-flow system (>100mL), and reducing the cost of expensive reagents (such as standard protein solutions) per test from ¥200 to ¥20; the small-sized membrane can directly use waste membrane scraps from the laboratory, further reducing consumable costs.

[0025] (4) Integration and simplified operation, greatly improving efficiency: All functional components (high pressure pump, pressure sensor, paperless recorder, etc.) are integrated into the metal shell. The external platform holds the membrane test container, magnetic stirrer and constant temperature water bath. The overall footprint is <0.3m² (70% smaller than the traditional system of 1m²). The membrane can be installed and removed in 3 minutes by hand-tightening the screws (the traditional cross-flow system takes 20 minutes). The pipeline adopts 1 / 16 liquid chromatography pipeline (high pressure ≥100bar) quick-connect connection, with no exposed pipeline. Only 12mL of pure water is needed for rinsing (the traditional cross-flow system requires more than 500mL).

[0026] (5) Real-time pressure monitoring to avoid membrane damage risk in advance: The pressure sensor (accuracy 0.01 bar) and the paperless recorder (1 Hz sampling frequency) can generate continuous pressure curves in real time and automatically store them as CSV format files. It can capture the pressure rise of 0.01 bar at the initial stage of membrane fouling (such as from 30.00 bar to 30.05 bar), terminate the experiment in advance to prevent membrane damage, and replace manual recording to reduce human error by 90%.

[0027] (6) The stirring function is specifically optimized to ensure the validity of the test: The magnetic stirrer is located directly below the membrane test container and drives the magnetic rotor inside the container to rotate (the speed is adjustable). It is specifically used to weaken the concentration polarization effect of the membrane surface, which is different from the mechanical stirring in traditional equipment that is only used for mixing liquids (such as stirring acetic acid and reducing agent in the comparison document). This further ensures that the test data reflects the performance of the membrane itself.

[0028] Furthermore, this solution breaks through traditional design concepts: it uses a high-pressure constant flow pump for the first time to supply pressure to the separation membrane, making the pressurization device and the membrane test chamber an integrated system (in the comparative document, the air pressure pump and the separation membrane are independent modules with no connection); the membrane test container adopts an independent design and is paired with chromatographic pipelines to achieve a high-pressure sealed connection, solving the pressure loss and leakage problems of traditional split systems.

[0029] Second, the expected benefits and commercial value of the technical solution of this utility model after its transformation are as follows:

[0030] In terms of cost: the cost of reagents per experiment is reduced by 90% (expensive reagents are reduced from ¥200 to ¥20), membrane consumables can be made from waste scraps, and maintenance costs are significantly reduced due to the long life of ceramic plungers (>5000 hours) and an 80% reduction in equipment failure rate;

[0031] In terms of efficiency: the membrane assembly and disassembly time is reduced from 20 minutes to 3 minutes, the experimental debugging time is reduced by 90%, and the 0.3m² desktop-level volume is suitable for high-frequency testing scenarios in the laboratory, which can greatly improve the experimental efficiency of membrane research and development and process optimization.

[0032] Safety and Market Perspective: Eliminates the risk of high-pressure gas cylinder leakage; metal casing protects high-pressure components from accidental contact; safety meets laboratory operating standards; the product can fill the market gap for "high-pressure dead-end constant current membrane testing equipment," replacing traditional low-pressure dead-end and high-pressure cross-flow systems; targeting membrane material R&D companies, university laboratories, and other customer groups, it has clear and considerable commercial promotion value.

[0033] The technical solution of this utility model fills a technical gap in the industry at home and abroad: This application is the first to integrate "high pressure plunger infusion pump (constant flow closed loop) + micro dead end filter chamber + magnetic anti-polarization stirring + high pressure connection of chromatographic pipeline + real-time pressure recording" into one unit, realizing constant flow performance testing of high pressure nanofiltration membrane and reverse osmosis membrane in laboratory scenarios, filling this technical gap.

[0034] The technical solution of this utility model solves a long-standing technical problem that people have long desired to solve but have never been able to achieve: This application solves the above-mentioned long-standing technical problems by using a high-pressure plunger pump (no gas cylinder), constant flow closed-loop control (constant throughput), 12mL micro container (small material liquid), 0.01bar precision real-time pressure curve (contamination early warning), integrated metal shell (small volume + quick assembly and disassembly), and innovatively integrating the high-pressure pump with the membrane test chamber, using magnetic stirring to weaken polarization, and making the chromatographic tubing resistant to high pressure.

[0035] The technical solution of this utility model overcomes technical biases: This application uses a high-pressure plunger infusion pump to achieve a pressure of >60 bar while reducing the equipment volume by more than 50%, breaking this perception; This application proves that the constant flow mode can eliminate flux interference, reducing the experimental CV value from ±15% to ±2%, resulting in more accurate data; This application uses magnetic stirring inside the container to specifically weaken polarization, verifying the key role of stirring in the effectiveness of membrane testing; This application integrates the high-pressure pump and the membrane testing chamber into one unit, and uses chromatographic tubing to achieve a high-pressure sealed connection, breaking the mindset of separate design; This application uses a 12mL microfiltration chamber to achieve high-pressure testing, subverting this traditional perception and successfully overcoming the aforementioned technical biases. Attached Figure Description

[0036] Figure 1 is a schematic diagram of the overall composition and connection of the device provided in an embodiment of this utility model;

[0037] Figure 2 is a schematic diagram of the structure of the miniature cylindrical membrane filter container (filter) provided in the embodiment of this utility model;

[0038] Figure 3 is a schematic diagram of the device connection of the prominent pressure monitoring unit provided in an embodiment of this utility model;

[0039] Figure 4 is a schematic diagram of the overall connection of the prominent constant temperature water bath device provided in the embodiment of this utility model;

[0040] Figure 5 shows the actual appearance of the constant temperature water bath device provided in this embodiment of the utility model and its cooperation with the membrane container;

[0041] Figure 6 is a diagram of the high-voltage dead-end constant current separation membrane performance testing equipment provided in an embodiment of this utility model;

[0042] In the diagram: 1. High-pressure plunger infusion pump; 2. Feed bottle; 3. Pressure monitoring and recording unit; 31. Pressure sensor; 32. Paperless recorder; 4. Magnetic stirrer; 5. Miniature cylindrical membrane filter container; 51. Stainless steel top cover; 52. Stainless steel bottom cover; 53. Magnetic rotor; 54. Magnetic stirring rod; 55. Screw plug; 56. Chromatography tubing connector; 57. Porous foam metal gasket; 58. Membrane to be tested; 59. Flow channel; 6. Constant temperature water bath; 61. Temperature controller; 62. Heating rod; 63. Permeate outlet; 64. Water level observation window; 7. 1 / 16 liquid chromatography tubing; 8. Permeate collection bottle. Detailed Implementation

[0043] To make the objectives, technical solutions, and advantages of this utility model clearer, the following detailed description is provided in conjunction with embodiments. It should be understood that the specific embodiments described herein are merely illustrative and not intended to limit the scope of this utility model.

[0044] like Figure 1 As shown, this utility model embodiment provides a high-pressure dead-end constant current separation membrane performance testing device, characterized in that it includes a metal shell and a high-pressure plunger infusion pump 1 integrated in the metal shell or fixed to the metal shell platform, a micro cylindrical membrane filter container 5, a pressure monitoring and recording unit 3, a magnetic stirrer 4, and a constant temperature water bath device 6.

[0045] The input end of the high-pressure plunger infusion pump 1 is connected to the feed bottle 2, and the output end is connected to the micro cylindrical membrane filter container 5 through a 1 / 16 liquid chromatography line 7. The high-pressure plunger infusion pump 1 can provide a liquid pressure of >60 bar, and the flow rate control accuracy is up to 0.01 mL / min and supports constant flow closed-loop control.

[0046] The volume of the micro cylindrical membrane filter container 5 is 12mL, the diameter of the compatible membrane is 3cm, the constant temperature water bath device 6 is sleeved on the outside of the micro cylindrical membrane filter container 5, and the magnetic stirrer 4 is located directly below the micro cylindrical membrane filter container 5, which can drive the magnetic rotor inside the container to rotate.

[0047] The pressure monitoring and recording unit 3 includes a pressure sensor 31 and a paperless recorder 32. The pressure sensor 31 is connected in series in the pipeline between the high-pressure plunger infusion pump 1 and the miniature cylindrical membrane filter container 5, with a measurement accuracy of 0.01 bar. The paperless recorder 32 is electrically connected to the pressure sensor 31.

[0048] Furthermore, the high-pressure plunger infusion pump 1 uses a corrosion-resistant ceramic plunger with a service life of >5000 hours.

[0049] Furthermore, the micro cylindrical membrane filter container 5 includes a stainless steel upper cover 51, a stainless steel lower cover 52, a magnetic rotor 53, a magnetic stirring rod 54, a screw plug 55, a chromatography tubing connector 56, and a porous foam metal gasket 57; the porous foam metal gasket 57 is disposed inside the stainless steel lower cover 52, the membrane to be tested 58 is placed on the porous foam metal gasket 57, the stainless steel upper cover 51 and the stainless steel lower cover 52 are fastened and sealed by the hand-tightening screw 55, and the chromatography tubing connector 56 is disposed at the corresponding interface of the stainless steel upper cover 51 and the lower cover, and is adapted to the 1 / 16 liquid chromatography tubing 7.

[0050] Furthermore, the paperless recorder 32 has a sampling frequency of 1Hz, can generate continuous pressure curves in real time, and automatically store the pressure data as a CSV format file.

[0051] Furthermore, the temperature control range of the constant temperature water bath device 6 is 5-95℃, and the temperature control accuracy is ±0.5℃. The bottom area of ​​the container of the constant temperature water bath device 6 is similar to that of the bottom area of ​​the magnetic stirrer 4, and the height is consistent with that of the micro cylindrical membrane filter container 5.

[0052] Furthermore, the metal casing is equipped with a modular mounting bracket inside for fixing the high-pressure plunger infusion pump 1 and the paperless recorder 32; the overall floor area of ​​the metal casing is <0.3m², and the external platform is used to place the miniature cylindrical membrane filter container 5, the magnetic stirrer 4, and the constant temperature water bath device 6.

[0053] This utility model discloses a high-voltage dead-end constant current separation membrane performance testing device, which is composed of functional module groups and a metal shell. Each functional module is integrated inside the shell or fixed to the shell platform. The specific structure is as follows:

[0054] High-pressure plunger infusion pump 1: As the core driving component for pressure and flow, the input end is connected to the feed bottle 2, and the output end is connected to the membrane test container through a 1 / 16 liquid chromatography tubing 7 (withstanding high pressure ≥100 bar); it can provide liquid pressure >60 bar, and the flow rate control accuracy is up to 0.01 mL / min, supporting constant flow closed-loop control (compensating for pressure fluctuations through plunger frequency feedback).

[0055] Miniature cylindrical membrane filter container 5: It is a custom-assembled structure with a volume of 12mL and a membrane diameter of 3cm (effective membrane area of ​​7cm²). It includes a stainless steel top cover, bottom cover, magnetic rotor, sealing gasket, hand-tightening screw, and chromatography tubing connector. The bottom cover has a built-in porous foam metal gasket (to support the membrane). The container is equipped with a magnetic rotor (which works with an external magnetic stirrer). The membrane can be quickly assembled and disassembled within 3 minutes by hand-tightening the screw.

[0056] Pressure monitoring and recording unit 3: It consists of pressure sensor 31 (range 0-100 bar, accuracy 0.01 bar) and paperless recorder 32; pressure sensor 31 is connected in series with the inlet pipeline of the membrane container to collect pipeline pressure in real time; paperless recorder 32 has a sampling frequency of 1 Hz, can generate continuous pressure curves and automatically store them as CSV files, replacing manual recording.

[0057] Magnetic stirrer 4: Fixed to the outer shell platform, located directly below the membrane test container, it drives the magnetic rotor inside the container to rotate (speed adjustable from 0-1000 rpm) through a magnetic field, which is used to weaken the concentration polarization effect of the membrane surface.

[0058] Constant temperature water bath device 6: It is a customized and adaptable structure with a volume that matches the bottom area of ​​the magnetic stirrer and a height that matches the membrane test container; it achieves constant temperature control of 5-95℃ through electric heating rods and temperature sensors. The membrane test container is embedded in the water bath to ensure stable liquid temperature (temperature control accuracy ±0.5℃).

[0059] Metal casing: Made of 304 stainless steel, with internal modular mounting brackets (for fixing the high-pressure pump and paperless recorder), and an external platform for placing the membrane container, magnetic stirrer and constant temperature water bath; the overall footprint is <0.3m², and it also serves to protect high-pressure components and prevent accidental contact.

[0060] Principles and procedures of use:

[0061] The equipment composition and connection are shown in Figure 1. Except for the magnetic stirrer 4 and the micro cylindrical membrane filter container 5, which are placed on the outer shell platform, all other parts of the equipment are placed or fixed in the metal shell, thus ensuring a compact size.

[0062] During use and operation, the test solution is first injected into the miniature cylindrical membrane filter container 5 using a syringe until it is full. Then, the high-pressure plunger pump 1 draws the required solution or feed liquid from the feed bottle 2 and introduces it into the miniature cylindrical membrane filter container 5 along the 1 / 16 liquid chromatography tubing 7 at a constant flow rate (which can be set via the pump control key). The pressure sensor 31 in the pressure monitoring and recording unit 3 works in conjunction with the paperless recorder 32 to detect and record the pressure in the feed liquid tubing connected to the miniature cylindrical membrane filter container 5. This pressure is the feed liquid pressure applied to the membrane 58 under test.

[0063] Driven by the high-pressure plunger pump 1, the feed solution continuously flows into the micro-cylindrical membrane filter container 5. Simultaneously, due to the constant volume of the micro-cylindrical membrane filter container 5 and the incompressibility of the feed solution, the volume of feed solution flowing into the container is equal to the volume of feed solution permeating from the membrane surface. The permeated feed solution, as the permeate, flows out from the 1 / 16 liquid chromatography line 7 at the bottom of the container (and can eventually be collected in the permeate collection bottle 8). Thus, under the pressure of the high-pressure plunger pump 1, the feed solution passes through the test membrane 58 fixed at the bottom of the micro-cylindrical membrane filter container 5 (supported by a porous foam metal gasket 57), completing the filtration and separation process, and flows out along the 1 / 16 liquid chromatography line 7 at the bottom, which is the permeate.

[0064] During this process, the magnetic rotor 53 inside the micro cylindrical membrane filter container 5 rotates at a set speed (which can be adjusted by the magnetic stirrer 4) driven by the external magnetic stirrer 4, forming a flow on the surface of the membrane 58 to be tested, reducing the concentration polarization of the membrane surface and ensuring the smooth completion of the filtration process; at the same time, the constant temperature water bath device 6 (which can be adjusted by the temperature controller 61) installed on the outside of the micro cylindrical membrane filter container 5 maintains the stable temperature of the liquid, ensuring that the test conditions are controllable.

[0065] Finally, by measuring the concentration of the remaining feed liquid (retentate) and the concentration of the permeate in the micro cylindrical membrane filter container 5, the retention rate of the membrane 58 to the feed liquid can be calculated. By recording the filtration time and combining it with the set flow rate of the high-pressure plunger pump 1 and the effective membrane area of ​​the membrane 58 (fixed at 0.5 cm²), the membrane flux of the membrane 58 can be calculated.

[0066] Retention rate calculation: R = 1 - [(2 × C)] p ) / (C f + C r ) ]

[0067] C p Permeate concentration (g / L, converted from conductivity-concentration standard curve)

[0068] C f The initial feed concentration (g / L) can be obtained from the permeate concentration and the retentate concentration based on feed balance, and is related to the permeate volume.

[0069] C r : retentate concentration (g / L)

[0070] Pure water flux calculation: PWP = J p / TMP; Jp = V p / (A m × t)

[0071] J p Water flux (L·m⁻²·h⁻¹)

[0072] TMP: Transmembrane pressure (bar)

[0073] V p : Permeate volume (L)

[0074] A m Effective membrane area (m²)

[0075] t: Filtering time (h)

[0076] In the description of this utility model, unless otherwise stated, "a plurality of" means two or more; the terms "upper," "lower," "left," "right," "inner," "outer," "front end," "rear end," "head," "tail," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. In addition, the terms "first," "second," "third," etc., are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0077] The above description is only a specific embodiment of this utility model, but the protection scope of this utility model is not limited thereto. Any modifications, equivalent substitutions and improvements made by those skilled in the art within the technical scope disclosed in this utility model, and within the spirit and principles of this utility model, should be included within the protection scope of this utility model.

Claims

1. A high-voltage dead-end constant current separation membrane performance testing device, characterized in that, It includes a metal casing and a high-pressure plunger infusion pump, a miniature cylindrical membrane filter container, a pressure monitoring and recording unit, a magnetic stirrer, and a constant temperature water bath device integrated into or fixed to the metal casing platform. The input end of the high-pressure plunger infusion pump is connected to the feed bottle, and the output end is connected to the micro cylindrical membrane filter container through a 1 / 16 liquid chromatography line. The high-pressure plunger infusion pump can provide a liquid pressure of >60 bar, and the flow rate control accuracy is up to 0.01 mL / min and supports constant flow closed-loop control. The volume of the micro cylindrical membrane filter container is 12 mL, the diameter of the compatible membrane is 3 cm, the constant temperature water bath device is sleeved on the outside of the micro cylindrical membrane filter container, and the magnetic stirrer is located directly below the micro cylindrical membrane filter container, which can drive the magnetic rotor inside the container to rotate. The pressure monitoring and recording unit includes a pressure sensor and a paperless recorder. The pressure sensor is connected in series in the pipeline between the high-pressure plunger infusion pump and the miniature cylindrical membrane filter container, with a measurement accuracy of 0.01 bar. The paperless recorder is electrically connected to the pressure sensor.

2. The high-voltage dead-end constant current separation membrane performance testing equipment according to claim 1, characterized in that, The high-pressure plunger infusion pump uses a corrosion-resistant ceramic plunger with a service life of >5000 hours.

3. The high-voltage dead-end constant current separation membrane performance testing equipment according to claim 1, characterized in that, The miniature cylindrical membrane filter container includes a stainless steel upper cover, a stainless steel lower cover, a magnetic rotor, a magnetic stirring rod, a screw plug, a chromatography tubing connector, and a porous foam metal gasket. The porous foam metal gasket is located inside the stainless steel lower cover, and the membrane to be tested is placed on the porous foam metal gasket. The stainless steel upper cover and the stainless steel lower cover are fastened and sealed by hand-tightening screws. The chromatography tubing connector is located at the corresponding interface of the stainless steel upper cover and the lower cover and is compatible with the 1 / 16 liquid chromatography tubing.

4. The high-voltage dead-end constant current separation membrane performance testing equipment according to claim 1, characterized in that, The paperless recorder has a sampling frequency of 1Hz, can generate continuous pressure curves in real time, and automatically stores the pressure data as a CSV format file.

5. The high-voltage dead-end constant current separation membrane performance testing equipment according to claim 1, characterized in that, The temperature control range of the constant temperature water bath device is 5-95℃, and the temperature control accuracy is ±0.5℃. The bottom area of ​​the container of the constant temperature water bath device is similar to that of the bottom area of ​​the magnetic stirrer, and the height is consistent with the height of the micro cylindrical membrane filter container.

6. The high-voltage dead-end constant current separation membrane performance testing equipment according to claim 1, characterized in that, The metal casing houses a modular mounting bracket for securing the high-pressure plunger infusion pump and the paperless recorder; the overall footprint of the metal casing is <0.3m². 2 The external platform is used to house the micro cylindrical membrane filter container, the magnetic stirrer, and the constant temperature water bath device.

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