Cell detection shaking mixer

Abstract

The utility model relates to cell detection technical field, concretely is a kind of cell detection concussion homogenizer, the utility model includes base, rotatingly installed with pivot in the base middle part, eccentric wheel one is slidably connected to pivot upper end, the position of eccentric wheel one upper end near edge is fixedly connected with the tray for installing test tube rack, the drive assembly for driving pivot rotation is installed in base interior, annular groove is set up in base upper end, eccentric wheel one lower end slides in annular groove, hole is set up in annular groove and is penetrated through base top, upper top subassembly is fixedly connected to base inner wall top, and the moving end of upper top subassembly is inserted with hole and is matched with, for driving tray up and down to shake;This cell detection concussion homogenizer possesses two kinds of mode of circumference track concussion and up and down concussion, and the mode of concussion is various, need not frequently replace equipment, and the degree of complexity of cell detection process drops, and efficiency improves.

Description

Technical Field

[0001] This utility model relates to the field of cell detection, specifically a cell detection oscillating mixer. Background Technology

[0002] In life sciences and medical testing fields such as cell detection, immunoassay, and biochemical reactions, shaking and mixing is a crucial pretreatment step. Its purpose is to ensure that the sample and reagents are thoroughly mixed and homogeneous, or that cells are uniformly suspended in the culture medium, thereby ensuring the accuracy and reliability of the test results.

[0003] Traditional orbital oscillators achieve mixing by using a tray to make horizontal circular motions. This motion mode is gentle and suitable for scenarios such as cell suspension, but it has low mixing efficiency for viscous samples or samples with tightly packed sediments, and may pose a risk of incomplete mixing.

[0004] Existing cell detection oscillators are limited in function and have fixed oscillation modes, with only one of circular or vertical oscillation possible. In practice, operators need to switch between different oscillation modes on different devices according to the characteristics of different cell samples (such as viscosity and cell sensitivity), which is cumbersome and inefficient. Therefore, a cell detection oscillator is proposed. Utility Model Content

[0005] The purpose of this invention is to provide a cell detection oscillator that can switch between different oscillation modes on a single device, in order to solve the problems mentioned in the background art.

[0006] The objective of this utility model can be achieved through the following technical solutions:

[0007] A cell detection shaking mixer includes a base, a rotating shaft rotatably mounted in the middle of the base, an eccentric wheel slidably connected to the upper end of the rotating shaft, a tray for mounting a test tube rack fixedly connected to the upper end of the eccentric wheel near its edge, a drive assembly for driving the rotating shaft to rotate inside the base, an annular groove opened at the upper end of the base, the lower end of the eccentric wheel sliding in the annular groove, a hole penetrating the top of the base opened in the annular groove, an upper push assembly fixedly connected to the top of the inner wall of the base, the movable end of the upper push assembly being inserted into the hole to drive the tray to shake up and down.

[0008] Preferably, the drive assembly includes a first bevel gear and a second bevel gear, the first bevel gear being coaxially fixed to the rotating shaft, a first servo motor being fixed inside the base, the output end of the first servo motor being fixed to the center of the second bevel gear, and the first bevel gear and the second bevel gear meshing and transmitting power.

[0009] Preferably, the upper jacking assembly includes a bracket, which is fixed to the inner wall of the base. A slide plate is slidably installed inside the bracket, and a protrusion is fixed to the upper end of the slide plate. The protrusion is inserted into a hole for jacking the eccentric wheel.

[0010] Preferably, a second servo motor is fixedly connected to the top of the inner wall of the base, and a cam is fixedly connected to the output end of the second servo motor. The cam is located inside the bracket and is in a pressing fit with the lower end of the slide plate.

[0011] Preferably, an eccentric wheel two is fixedly connected to the side wall of the rotating shaft. The eccentric wheel two and the eccentric wheel one are arranged at 180 degrees diagonally. A load-bearing block is installed on the eccentric wheel two. A sliding groove is opened at the upper end of the shaft body. The drive shaft of the eccentric wheel one is slidably connected to the sliding groove.

[0012] Preferably, a support ring is fixedly connected to the upper end of the machine base, the tray rotates on the support ring, and a sealing cover is snapped onto the upper end of the machine base for covering the tray.

[0013] The beneficial effects of this utility model are:

[0014] This invention uses a drive component to rotate a shaft, which in turn drives an eccentric wheel to rotate. This causes the eccentric wheel to rotate a tray, resulting in circumferential oscillation of the cells on the tray. When the shaft stops, an upper component is inserted into the hole, continuously pushing the eccentric wheel upwards, causing the cells on the tray to oscillate up and down. This cell detection oscillator has two modes: circumferential oscillation and up-and-down oscillation. With diverse oscillation modes, it eliminates the need for frequent equipment changes, reduces the complexity of the cell detection process, and improves efficiency. Attached Figure Description

[0015] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, for those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0016] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0017] Figure 2 This is a schematic diagram of the base structure of this utility model;

[0018] Figure 3 This is a schematic diagram of the internal structure of the base of this utility model;

[0019] Figure 4 This is an enlarged cross-sectional view of the base structure of this utility model;

[0020] The attached figures are labeled as follows:

[0021] 1. Base; 2. Sealing cover; 3. Tray; 4. Support ring; 5. Annular groove; 6. Eccentric wheel one; 7. Rotating shaft; 8. Bevel gear one; 9. Bevel gear two; 10. Servo motor one; 11. Eccentric wheel two; 12. Load-bearing block; 13. Bracket; 14. Slide plate; 15. Protrusion; 16. Cam; 17. Hole; 18. Slide groove; 20. Servo motor two. Detailed Implementation

[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present utility model.

[0023] A cell detection oscillator, such as Figures 1-4 As shown, the device includes a base 1 made of metal or high-strength engineering plastic. A rotating shaft 7 is rotatably mounted in the middle of the base 1. The rotating shaft 7 is vertically positioned, with its bottom rotatably mounted to the inner wall of the base 1 via bearings, and its upper end rotatably mounted to the upper end of the base 1 via bearings. An eccentric wheel 6 is slidably connected to the upper end of the rotating shaft 7. A tray 3 for mounting a test tube rack is fixedly attached to the upper edge of the eccentric wheel 6. The drive shaft of the eccentric wheel 6 is inserted into the upper end of the rotating shaft 7 and slidably mounted thereto. The sliding method is up and down sliding, allowing the eccentric wheel 6 to slide up and down a certain height on the rotating shaft 7, but it cannot detach. A device for... A drive assembly that drives the rotating shaft 7 is located on one side of the rotating shaft 7, thereby reducing the thickness of the base 1. An annular groove 5 is provided at the upper end of the base 1, and the lower end of the eccentric wheel 6 slides in the annular groove 5. The annular groove 5 provides a circumferential track for the rotation of the eccentric wheel 6. A hole 17 that penetrates the top of the base 1 is provided in the annular groove 5, so that the interior of the base 1 and the interior of the annular groove 5 are connected. An upper top assembly is fixed to the top of the inner wall of the base 1. The moving end of the upper top assembly is inserted into the hole 17 to drive the tray 3 to shake up and down. The tray 3 is provided with holes 17 of various sizes, which are used to install cell tube racks with the help of positioning pins or bolts.

[0024] The drive assembly includes a first bevel gear 8 and a second bevel gear 9. The first bevel gear 8 is coaxially fixed to the rotating shaft 7. A first servo motor 10 is fixed inside the base 1. The output end of the first servo motor 10 is fixed to the center of the second bevel gear 9. The first bevel gear 8 and the second bevel gear 9 mesh and drive each other. The diameter of the first bevel gear 8 is larger than the diameter of the second bevel gear 9.

[0025] The motor base 1 of the servo motor 10 (model MSME042G1U) is installed inside the base 1. Through the meshing of bevel gear 8 and bevel gear 9, the servo motor 10 drives the rotating shaft 7 to rotate, which in turn drives the upper tray 3 to make a horizontal circular track movement. The speed and direction of the servo motor 10 can be precisely programmed and controlled by a controller (such as a PLC or a dedicated control board). This is existing technology and will not be elaborated further.

[0026] The upper assembly includes a bracket 13, which is fixed to the inner wall of the base 1. A slide plate 14 is slidably installed inside the bracket 13. A protrusion 15 is fixed to the upper end of the slide plate 14. The protrusion 15 is inserted into the hole 17 for pushing the eccentric wheel 6.

[0027] When tray 3 stops rotating, shaft 7 returns to its original position. Each time shaft 7 stops rotating, it returns to its original state, so that eccentric wheel 6 and tray 3 return to their positions before oscillation. This is achieved by controlling the number of rotations of the output shaft of servo motor 10, or by installing relevant sensors in the base 1 for control. This is existing technology and will not be elaborated further. When shaft 7 stops rotating, the position of eccentric wheel 6 is just above hole 17. When slide plate 14 is raised, protrusion 15 pushes eccentric wheel 6 from hole 17, causing eccentric wheel 6 to oscillate up and down.

[0028] Servo motor 20 (Panasonic Minas A6 series MSME012G1U) is fixedly installed on the inner wall of the base 1. The output shaft of servo motor 20 rotates, which drives cam 16 to rotate, causing cam 16 to push slide plate 14 or slide plate 14 to drop due to gravity, causing protrusion 15 to continuously push eccentric wheel 6 up and down, causing the test tube rack on tray 3 to vibrate up and down.

[0029] An eccentric wheel 11 is fixedly connected to the side wall of the rotating shaft 7. The eccentric wheel 11 and the eccentric wheel 6 are arranged diagonally at 180 degrees. A load-bearing block 12 is installed on the eccentric wheel 11. The load-bearing block 12 is replaceable. The weight is calculated based on the tray 3 and the test tube rack above it to offset the "tension" generated by the rotation of the eccentric wheel 6. The entire rotating shaft 7 rotation system achieves force balance on the horizontal plane, thereby reducing the vibration caused by the rotation of the rotating shaft 7. A sliding groove 18 is opened at the upper end of the shaft body. The side wall of the sliding groove 18 is provided with a recessed rectangular vertical groove. The drive shaft of the eccentric wheel 6 (the side wall is provided with a rectangular groove adapted to the rectangular vertical groove) The rectangular strip is slidably connected to the slide groove 18 (the upper end of the rectangular vertical groove will not penetrate the slide groove 18, so that the rectangular strip cannot be detached, and the eccentric wheel 6 will not detach from the top of the rotating shaft 7). The drive shaft of the eccentric wheel 6 is slidably connected to the upper end of the rotating shaft 7 through the slide groove 18. In order to further increase the ability of the tray 3 to oscillate up and down, a spring in a stretched state is set at the bottom of the inner wall of the slide groove 18. The end of the spring is fixed to the bottom of the drive shaft of the eccentric wheel 6. It is pulled while the eccentric wheel 6 rotates to prevent the eccentric wheel 6 from detaching from the rotating shaft 7, and to facilitate the cam 16 to drive the tray to oscillate up and down.

[0030] A support ring 4 is fixedly connected to the upper end of the base 1, and the tray 3 rotates on the support ring 4. A sealing cover 2 is snapped onto the upper end of the base 1 to cover the tray 3.

[0031] The support ring 4 is located between the upper end of the tray 3 and the base 1 to support the tray 3. The sealing cover 2 can be put on during cell detection. The transparent sealing cover 2 is installed on the upper end of the base 1 by a snap-fit ​​structure to cover the entire area of ​​the tray 3. It does not affect the oscillation of the tray 3, can prevent foreign objects from entering, and can also provide a safety barrier during the cell oscillation and mixing process.

[0032] The working principle of the cell detection shaking mixer provided by this utility model is as follows:

[0033] When only servo motor 10 is activated, it drives shaft 7 to rotate via bevel gears 8 and 9, causing eccentric wheel 6 and tray 3 to perform stable horizontal circular motion, achieving circular track oscillation. When only servo motor 20 is activated, it periodically lifts tray 3 via cam 16 and upper lifting mechanism, causing it to vibrate vertically, achieving up-and-down oscillation. All operating parameters, such as rotation speed, vibration frequency, and running time, can be digitally set and stored through a connected external controller, achieving standardization and automation of the process. This cell detection oscillating mixer has two modes: circular track oscillation and up-and-down oscillation, providing diverse oscillation modes. It eliminates the need for frequent equipment changes, reduces the complexity of the cell detection process, and improves efficiency.

[0034] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model.

Claims

1. A cell detection oscillating mixer, comprising a base (1), characterized in that, A rotating shaft (7) is rotatably mounted in the middle of the base (1). An eccentric wheel (6) is slidably connected to the upper end of the rotating shaft (7). A tray (3) for mounting a test tube rack is fixedly connected to the upper end of the eccentric wheel (6) near the edge. A drive assembly for driving the rotating shaft (7) is installed inside the base (1). An annular groove (5) is opened at the upper end of the base (1). The lower end of the eccentric wheel (6) slides in the annular groove (5). A hole (17) penetrating the top of the base (1) is opened in the annular groove (5). An upper top assembly is fixedly connected to the top of the inner wall of the base (1). The moving end of the upper top assembly is inserted into the hole (17) to drive the tray (3) to shake up and down.

2. The cell detection oscillating mixer according to claim 1, characterized in that, The drive assembly includes a first bevel gear (8) and a second bevel gear (9). The first bevel gear (8) is coaxially fixed to the rotating shaft (7). A first servo motor (10) is fixed inside the base (1). The output end of the first servo motor (10) is fixed to the center of the second bevel gear (9). The first bevel gear (8) and the second bevel gear (9) mesh and drive each other.

3. The cell detection oscillating mixer according to claim 1, characterized in that, The upper jacking assembly includes a bracket (13), which is fixed to the inner wall of the base (1). A slide plate (14) is slidably installed inside the bracket (13). A protrusion (15) is fixed to the upper end of the slide plate (14). The protrusion (15) is inserted into the hole (17) for jacking the eccentric wheel (6).

4. The cell detection oscillating mixer according to claim 3, characterized in that, A servo motor 2 (20) is fixedly connected to the top of the inner wall of the base (1). A cam (16) is fixedly connected to the output end of the servo motor 2 (20). The cam (16) is located inside the bracket (13) and is pressed against the lower end of the slide plate (14).

5. A cell detection oscillating mixer according to claim 1, characterized in that, The side wall of the rotating shaft (7) is fixed with an eccentric wheel two (11). The eccentric wheel two (11) and the eccentric wheel one (6) are arranged at 180 degrees diagonally. A load-bearing block (12) is installed on the eccentric wheel two (11). A sliding groove (18) is opened at the upper end of the shaft body. The drive shaft of the eccentric wheel one (6) is slidably connected to the sliding groove (18).

6. The cell detection oscillating mixer according to claim 1, characterized in that, The upper end of the base (1) is fixedly connected to a support ring (4), the tray (3) rotates on the support ring (4), and a sealing cover (2) is snapped onto the upper end of the base (1) for covering the tray (3).

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