Culture solution mixing device for stem cell culture

CN224656628UActive Publication Date: 2026-08-21TIANJIN JINHUA BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202521941646.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-09-10
Publication Date
2026-08-21
Estimated Expiration
2035-09-10

AI Technical Summary

Technical Problem

[0003]目前多采用试杯混合,各种培养液添加后,通过混合装置或手动进行搅拌混合,混合不够均匀,影响细胞培养的培养质量,且混合结束后,内壁残留有培养液,不便于后续进行清理

Benefits of technology

[0013](1)本实用新型所述的一种干细胞培养用的培养液混合装置,电机带动旋转辊转动时,同时带动搅拌叶和凹型刮板进行转动,能够对混合罐内的多种营养液充分的搅拌均匀,混合效果好,刮板外侧与混合罐内壁相互接触,可以沿着环形的导向轨对附着在混合罐内壁营养液刮离,避免附着过多的营养液,防止混合不均匀,影响混合的效果,后期对混合罐内壁清洗时,也可将内壁的附着物刮离、清洗干净。

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Abstract

The utility model relates to stem cell culture technical field, and specifically is a kind of culture solution mixing device for stem cell culture, including base, hydraulic cylinder and discharge valve, the base top is separately equipped with receiving tray and auxiliary telescopic column, the base top is welded support plate corresponding receiving tray side, the support plate front side is equipped with placing plate, the placing plate top is equipped with mixing tank, the top of support plate is equipped with control panel.Motor drives rotary roller to rotate, stirring blade and concave scraper are rotated simultaneously, can be fully stirred evenly to the various nutrient solution in mixing tank, and mixing effect is good, scraper outside and mixing tank inner wall are contacted each other, can be scraped off the nutrient solution adhered in mixing tank inner wall along annular guide rail, avoid adhering too much nutrient solution, prevent mixing uneven, affect the effect of mixing, when cleaning mixing tank inner wall in later period, adherend on inner wall can also be scraped off, cleaned.
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Description

Technical Field

[0001] This utility model relates to the field of stem cell culture technology, and specifically to a culture medium mixing device for stem cell culture. Background Technology

[0002] Cell culture, also known as cell cloning technology, is a crucial process in biology, requiring the mixing of various nutrient solutions. This process is essential for both the broader field of bioengineering and the specific application of biological cloning.

[0003] Currently, mixing is mostly done in test cups. After adding various culture media, the mixture is stirred manually or using a mixing device. However, this method results in uneven mixing, affecting the quality of cell culture. Furthermore, culture media residue remains on the inner wall after mixing, making subsequent cleaning difficult. Therefore, a culture medium mixing device for stem cell culture is proposed to facilitate the scraping off of nutrient media adhering to the inner wall of the mixing vessel. This device also allows for the removal and cleaning of the inner wall during subsequent cleaning, improving the mixing effect and quality. Utility Model Content

[0004] To address the problems in the existing technology, this utility model provides a culture medium mixing device for stem cell culture, which facilitates the scraping off of nutrient solution adhering to the inner wall of the mixing tank. During subsequent cleaning of the inner wall of the mixing tank, the adhering substances can also be scraped off and cleaned, thereby improving the mixing effect and quality.

[0005] The technical solution adopted by this utility model to solve its technical problem is a culture medium mixing device for stem cell culture, including a base, a hydraulic cylinder and a discharge valve. The top of the base is respectively provided with a receiving tray and an auxiliary telescopic column. A support plate is welded to the side of the top of the base corresponding to the receiving tray. A placement plate is provided on the front side of the support plate. A mixing tank is provided on the top of the placement plate. A control panel is provided on the top of the support plate.

[0006] The mixing tank is equipped with stirring blades and concave scrapers. The top of the mixing tank is equipped with a top cover, and a motor is located at the center of the top of the top cover.

[0007] Specifically, two sets of mounting slots are opened on the front side of the support plate. A hydraulic cylinder is installed in the top of the mounting slot by bolts. A mounting plate is welded to the bottom drive end of the hydraulic cylinder. One end of the mounting plate is connected to the placement plate by bolts.

[0008] Specifically, the bottom of the mixing tank is connected to the discharge valve via a pipe that passes through a reserved opening at the top of the placement plate.

[0009] Specifically, a guide rail is provided on the upper half of the inner wall of the mixing tank, and a rotating roller is connected to the bottom of the mixing tank corresponding to the bottom of the top cover via a rotating shaft. Stirring blades are evenly provided on the outer periphery of the rotating roller from top to bottom. A concave scraper is installed on the bottom of the outer periphery of the rotating roller via bolts, and the side of the concave scraper is arc-shaped and slidably connected to the guide rail via a slider.

[0010] Specifically, an arc-shaped baffle is provided in the mounting groove on one side of the top cover, and the top of the arc-shaped baffle is connected to the inner wall of the top cover through a rotating shaft. A handrail is installed at one point of the top of the arc-shaped baffle through bolts.

[0011] Specifically, the output terminal of the control panel is electrically connected to the auxiliary telescopic column, hydraulic cylinder, discharge valve, and motor input terminal via wires.

[0012] The beneficial effects of this utility model are:

[0013] (1) The culture medium mixing device for stem cell culture described in this utility model, when the motor drives the rotating roller to rotate, it also drives the stirring blade and concave scraper to rotate, which can fully mix the various nutrient solutions in the mixing tank and achieve good mixing effect. The outer side of the scraper is in contact with the inner wall of the mixing tank and can scrape off the nutrient solution adhering to the inner wall of the mixing tank along the annular guide rail, avoiding excessive nutrient solution adhering to the inner wall, preventing uneven mixing and affecting the mixing effect. When cleaning the inner wall of the mixing tank later, the adhering substances on the inner wall can also be scraped off and cleaned.

[0014] (2) The culture medium mixing device for stem cell culture described in this utility model can be activated by starting the control panel and simultaneously opening the hydraulic cylinder to drive the mounting plate to move the placement plate and the mixing tank, which is convenient for adjusting the height and can adapt to different specifications of tank height, making it convenient for filling. Then, the mixed culture medium can be quantitatively discharged by opening the discharge valve using the control panel. Attached Figure Description

[0015] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0016] Figure 1 This is a schematic diagram of the overall design of this utility model;

[0017] Figure 2 This is a schematic diagram of the support plate of this utility model;

[0018] Figure 3 This is a schematic diagram of the mixing tank of this utility model;

[0019] Figure 4 This is a schematic diagram of the top cover of this utility model;

[0020] In the diagram: 1. Base; 2. Receiving tray; 3. Auxiliary telescopic column; 4. Support plate; 5. Mounting groove; 6. Hydraulic cylinder; 7. Mounting plate; 8. Placement plate; 9. Mixing tank; 10. Control panel; 11. Discharge valve; 12. Guide rail; 13. Rotating roller; 14. Agitator blade; 15. Concave scraper; 16. Top cover; 17. Motor; 18. Arc-shaped baffle; 19. Handrail. Detailed Implementation

[0021] To make the technical means, creative features, objectives and effects of this utility model easier to understand, the present utility model will be further described below in conjunction with specific embodiments.

[0022] To facilitate the scraping off of nutrient solution adhering to the inner wall of the mixing tank, the deposits can also be scraped off and cleaned during subsequent cleaning of the inner wall, improving the mixing effect and quality. Figure 1-4 As shown, the culture medium mixing device for stem cell culture of this utility model includes a base 1, a hydraulic cylinder 6 and a discharge valve 11. The top of the base 1 is provided with a receiving tray 2 and an auxiliary telescopic column 3. A support plate 4 is welded to the top of the base 1 on the side corresponding to the receiving tray 2. A placement plate 8 is provided on the front side of the support plate 4. A mixing tank 9 is provided on the top of the placement plate 8. A control panel 10 is provided on the top of the support plate 4.

[0023] The mixing tank 9 is equipped with stirring blades 14 and concave scrapers 15. The top of the mixing tank 9 is equipped with a top cover 16, and a motor 17 is located at the center of the top of the top cover 16.

[0024] When in use, add various nutrient solutions into the mixing tank 9, and move the handle 19 to move the arc-shaped baffle 18 to seal the opening on one side of the top cover 16. The top and bottom of the arc-shaped baffle 18 are covered with silicone sealing strips. When closed, it can block the gap at the connection with the top cover 16, forming a certain degree of sealing and preventing the nutrient solution in the mixture from splashing out of the mixing tank 9.

[0025] When the motor 17 drives the rotating roller 13 to rotate, it also drives the stirring blade 14 and the concave scraper 15 to rotate, which can fully and evenly stir the various nutrient solutions in the mixing tank 9, resulting in a good mixing effect. The outer side of the scraper is in contact with the inner wall of the mixing tank 9, and can scrape off the nutrient solution adhering to the inner wall of the mixing tank 9 along the annular guide rail 12, avoiding excessive nutrient solution adhering to the inner wall, preventing uneven mixing, and affecting the mixing effect.

[0026] Restarting the control panel 10 simultaneously activates the hydraulic cylinder 6, which drives the mounting plate 7 to move the placement plate 8 and the mixing tank 9, allowing for easy height adjustment to accommodate different tank heights and facilitate filling. Then, using the control panel 10 to open the discharge valve 11 allows for the quantitative discharge of the mixed culture solution.

[0027] To facilitate adjustment of the height of mixing tank 9, for example, as shown... Figure 1 , Figure 2 As shown, the present invention also includes two sets of mounting grooves 5 on the front side of the support plate 4, a hydraulic cylinder 6 is mounted on the top of the mounting groove 5 by bolts, a mounting plate 7 is welded to the bottom drive end of the hydraulic cylinder 6, and one end of the mounting plate 7 is connected to the placement plate 8 by bolts.

[0028] For example, such as Figure 1 , Figure 2 , Figure 3 As shown, the present invention also includes a bottom of the mixing tank 9 connected to the discharge valve 11 via a pipe passing through a reserved opening at the top of the placement plate 8.

[0029] During use, the hydraulic cylinder 6 drives the mounting plate 7 to move the placement plate 8 and the mixing tank 9, which facilitates height adjustment and can adapt to different tank heights, making filling convenient. Then, the control panel 10 is used to open the discharge valve 11 to discharge the mixed culture solution in a quantitative manner.

[0030] For example, such as Figure 1 , Figure 3 As shown, this utility model also includes a guide rail 12 on the upper half of the inner wall of the mixing tank 9, a rotating roller 13 connected to the bottom of the top cover 16 at the bottom of the mixing tank 9 via a rotating shaft, a stirring blade 14 evenly provided from top to bottom on the outer periphery of the rotating roller 13, and a concave scraper 15 installed on the bottom of the outer periphery of the rotating roller 13 by bolts, and the side of the concave scraper 15 is arc-shaped and slidably connected to the guide rail 12 via a slider.

[0031] When in use, the motor 17 drives the rotating roller 13 to rotate, which in turn drives the stirring blade 14 and the concave scraper 15 to rotate. This can fully stir the various nutrient solutions in the mixing tank 9, resulting in a good mixing effect. The outer side of the scraper is in contact with the inner wall of the mixing tank 9, and can scrape off the nutrient solution adhering to the inner wall of the mixing tank 9 along the annular guide rail 12, avoiding excessive nutrient solution adhering to the inner wall and preventing uneven mixing that would affect the mixing effect.

[0032] For example, such as Figure 1 , Figure 4 As shown, the present invention also includes an arc-shaped baffle 18 provided in the mounting groove on one side of the top cover 16, and the top of the arc-shaped baffle 18 is connected to the inner wall of the top cover 16 through a rotating shaft, and a handrail 19 is installed at one point of the top of the arc-shaped baffle 18 by bolts.

[0033] When in use, the handle 19 is turned to move the arc-shaped baffle 18 into the mounting groove of the top cover 16, so that multiple nutrient solutions can be added into the mixing tank 9 at any time. The top and bottom of the arc-shaped baffle 18 are covered with silicone sealing strips. When closed, the gap at the connection with the top cover 16 can be blocked to form a certain degree of sealing and prevent the nutrient solution in the mixture from splashing out of the mixing tank 9.

[0034] For example, such as Figure 1 , Figure 2 , Figure 3 , Figure 4 As shown, this utility model also includes an electrical connection between the output end of the control panel 10 and the auxiliary telescopic column 3, the hydraulic cylinder 6, the discharge valve 11, and the input end of the motor 17, respectively, via wires.

[0035] When in use, the hydraulic cylinder 6 is activated via the control panel 10 to adjust the height of the mixing tank 9 and the amount of nutrient solution discharged, and the motor 17 is activated to drive the stirring blade 14 to rotate and mix the nutrient solution evenly.

[0036] When using this utility model, multiple nutrient solutions are added into the mixing tank 9. The handle 19 is turned to drive the arc-shaped baffle 18 to seal the opening on one side of the top cover 16. The top and bottom of the arc-shaped baffle 18 are covered with silicone sealing strips. When closed, the gap at the connection with the top cover 16 can be blocked to form a certain degree of sealing and prevent the nutrient solution in the mixture from splashing out of the mixing tank 9.

[0037] When the motor 17 drives the rotating roller 13 to rotate, it also drives the stirring blade 14 and the concave scraper 15 to rotate, which can fully and evenly stir the various nutrient solutions in the mixing tank 9, resulting in a good mixing effect. The outer side of the scraper is in contact with the inner wall of the mixing tank 9, and can scrape off the nutrient solution adhering to the inner wall of the mixing tank 9 along the annular guide rail 12, avoiding excessive nutrient solution adhering to the inner wall, preventing uneven mixing, and affecting the mixing effect.

[0038] Restarting the control panel 10 simultaneously activates the hydraulic cylinder 6, which drives the mounting plate 7 to move the placement plate 8 and the mixing tank 9, allowing for easy height adjustment to accommodate different tank heights and facilitate filling. Then, using the control panel 10 to open the discharge valve 11 allows for the quantitative discharge of the mixed culture solution.

[0039] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The descriptions of the above embodiments and specifications are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of protection claimed by this utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A culture medium mixing device for stem cell culture, characterized in that, Includes a base (1), a hydraulic cylinder (6) and a discharge valve (11). The top of the base (1) is provided with a receiving plate (2) and an auxiliary telescopic column (3). A support plate (4) is welded to the top of the base (1) on the side corresponding to the receiving plate (2). A placement plate (8) is provided on the front side of the support plate (4). A mixing tank (9) is provided on the top of the placement plate (8). A control panel (10) is provided on the top of the support plate (4). The mixing tank (9) is equipped with a stirring blade (14) and a concave scraper (15). The top of the mixing tank (9) is equipped with a top cover (16), and a motor (17) is located at the center of the top of the top cover (16).

2. The culture medium mixing device for stem cell culture according to claim 1, characterized in that, Two sets of mounting slots (5) are opened on the front side of the support plate (4). A hydraulic cylinder (6) is installed in the top of the mounting slot (5) by bolts. A mounting plate (7) is welded to the bottom drive end of the hydraulic cylinder (6). One end of the mounting plate (7) is connected to the placement plate (8) by bolts.

3. The culture medium mixing device for stem cell culture according to claim 1, characterized in that, The bottom of the mixing tank (9) is connected to the discharge valve (11) through a pipe that passes through the reserved opening at the top of the placement plate (8).

4. The culture medium mixing device for stem cell culture according to claim 1, characterized in that, The upper half of the inner wall of the mixing tank (9) is provided with a guide rail (12). The bottom of the mixing tank (9) is connected to the bottom of the top cover (16) via a rotating shaft and a rotating roller (13). The outer circumference of the rotating roller (13) is uniformly provided with stirring blades (14) from top to bottom. The bottom of the outer circumference of the rotating roller (13) is bolted with a concave scraper (15), and the side of the concave scraper (15) is arc-shaped and slidably connected to the guide rail (12) via a slider.

5. The culture medium mixing device for stem cell culture according to claim 1, characterized in that, An arc-shaped baffle (18) is provided in the mounting groove on one side of the top cover (16), and the top of the arc-shaped baffle (18) is connected to the inner wall of the top cover (16) through a rotating shaft. A handrail (19) is installed at one point of the top of the arc-shaped baffle (18) through a bolt.

6. The culture medium mixing device for stem cell culture according to claim 1, characterized in that, The output end of the control panel (10) is electrically connected to the auxiliary telescopic column (3), hydraulic cylinder (6), discharge valve (11) and motor (17) input end via wires.