A dry blood spot puncher with anti-spillage

Abstract

The utility model relates to biological sample processing equipment technical field discloses a kind of dry blood spot punchers of anti-spillage, the dry blood spot puncher of anti-spillage includes stamping module, replacement assembly with punch head is installed, collection bin and dismounting assembly.The collection bin is arranged below the stamping path of punch head, for directly collecting punch sample;The dismounting assembly is connected between stamping module and replacement assembly, for realizing the quick locking and release of replacement assembly.The replacement assembly inside is also through the linkage of setting connecting sleeve, push sleeve, ball and spring, the quick plug-in fixation of punch head is realized.The utility model is through setting closed collection bin and two-stage quick dismounting structure, solve the problem that dry blood spot sample is easy to spill and lose in prior art and punch head replacement is cumbersome, with sample collection reliable, effectively prevent cross-contamination, replacement convenient and efficient effect.

Description

Technical Field

[0001] This utility model relates to the field of biological sample processing equipment technology, and in particular to a leak-proof dried blood spot punch. Background Technology

[0002] Dried blood spot samples, formed by dripping collected blood onto specially made filter paper and allowing it to air dry, are widely used in newborn screening for genetic metabolic diseases, forensic evidence identification, and pharmacokinetic studies due to their advantages such as convenient collection, low storage and transportation costs. Before analyzing dried blood spot samples, a special dried blood spot punch is typically used to punch out a circular piece of paper containing blood from a sample card as the sample to be tested.

[0003] Existing dried blood spot punchers typically use a hollow punch head to press against the blood spot area, collecting the small paper fragments of the sample into centrifuge tubes or microplates below. However, this process presents a common technical challenge in biological sample processing equipment: the small paper fragments are extremely lightweight, and the filter paper material is highly susceptible to static electricity due to friction in dry environments.

[0004] When the punch head presses and lifts at high speed, the resulting airflow disturbance and electrostatic adsorption effect often cause small paper samples to fail to fall smoothly into the designated collection container due to gravity. These samples may adhere to the outer or inner wall of the punch head, or be blown to other locations on the worktable by the airflow, resulting in accidental sample loss. This sample loss not only necessitates re-punching, increasing the workload of operators and consuming valuable original samples, but more seriously, if the lost samples accidentally fall into other sample containers, it will cause catastrophic cross-contamination, directly affecting the accuracy of subsequent genetic testing or disease screening results. Utility Model Content

[0005] To overcome the above shortcomings, this utility model provides a spill-proof dried blood spot punch, which aims to improve the problems of sample spillage and loss due to static electricity or airflow disturbance after punching, resulting in sample loss and cross-contamination, and the cumbersome and time-consuming process of replacing the punch head. This utility model aims to provide a spill-proof dried blood spot punch with an improved structure that can effectively solve the above problems.

[0006] To achieve the above objectives, this utility model provides the following technical solution for biological sample processing equipment: a spill-proof dried blood spot punch, comprising: a stamping module and a replacement assembly with a punching head installed; as well as a collection chamber and a disassembly assembly.

[0007] The collection chamber is a closed structure for storing samples, which can effectively prevent samples from being lost or contaminated due to external environmental influences.

[0008] Furthermore, the collection chamber is positioned below the punching path of the punching head, ensuring that samples that fall off during punching can fall directly into the collection chamber due to gravity; the disassembly assembly is connected between the punching module and the replacement assembly, and the replacement assembly can be quickly locked or released as a whole through the disassembly assembly, which is convenient for maintenance and replacement.

[0009] Preferably, the collection chamber is provided with a door, which is used to close or open the retrieval port of the collection chamber to facilitate the storage and retrieval of samples.

[0010] Preferably, the disassembly assembly includes a rotating sleeve, a pressing plate, and a first spring; the rotating sleeve is provided with locking teeth, and the replacement assembly is provided with a locking plate that cooperates with the locking teeth; when the pressing plate is pressed, it drives the first spring and causes the rotating sleeve to rotate so that the locking teeth disengage from the locking plate.

[0011] In a further preferred embodiment, the disassembly assembly further includes a housing, the pressing plate being movably disposed on the housing, and the first spring being housed within the housing and abutting between the pressing plate and the rotating sleeve.

[0012] Preferably, the replacement component includes a connecting sleeve, and the punch head is pluggably installed in the connecting sleeve; the replacement component also includes a retaining ball, a second spring, and a pushing sleeve; the second spring applies elastic force to cause the retaining ball to engage in the slot of the punch head to fix the punch head, and the pushing sleeve is used to compress the second spring to disengage the retaining ball from the slot.

[0013] More preferably, the replacement component further includes a retaining ring, and the pushing sleeve is fitted around the outer periphery of the connecting sleeve and moves axially along the connecting sleeve under the limitation of the retaining ring.

[0014] Preferably, the spill-proof dried blood spot punch further includes a control console and a display screen mounted on the control console, the display screen being used to display operating parameters and status.

[0015] More preferably, the console is further provided with a button, which is electrically connected to the console.

[0016] This utility model has the following beneficial effects:

[0017] 1. In this utility model, by setting up a closed collection chamber located below the punching head, the punched sample falls directly into it, which solves the problem that dried blood spot samples are easy to spill or lose due to their light weight or static electricity, and may cause cross-contamination in existing biological sample processing equipment technology. This achieves the technical effect of biological sample processing equipment that ensures complete sample collection, safety and reliability, and effective prevention of contamination.

[0018] 2. This utility model, by designing a quick replacement mechanism consisting of disassembly and replacement components working in concert, utilizes mechanical linkages such as springs, locking teeth, and locking balls to solve the problems of cumbersome, time-consuming, and tool-required perforation head replacement processes in existing biological sample processing equipment. It achieves the technical effect of quick hand-operated perforation head replacement, convenient operation, and significantly improved equipment maintainability and work efficiency in biological sample processing equipment. Attached Figure Description

[0019] Figure 1 A three-dimensional structural diagram of a spill-proof dried blood spot punch proposed in this utility model;

[0020] Figure 2 This is a schematic diagram of the disassembly components of a spill-proof dried blood spot punch according to the present invention.

[0021] Figure 3 This is a schematic diagram of the display screen portion of a leak-proof dried blood spot puncher proposed in this utility model;

[0022] Figure 4 This is a schematic diagram of the replacement component of a spill-proof dried blood spot punch according to the present invention.

[0023] Legend:

[0024] 1. Collection compartment; 2. Compartment door; 3. Button; 4. Control panel; 5. Display screen; 6. Stamping module; 7. Disassembly assembly; 701. Housing; 702. First spring; 703. Pressing plate; 704. Rotating sleeve; 705. Clamping tooth; 706. Clamping plate; 8. Replacement assembly; 801. Pushing sleeve; 802. Second spring; 803. Fixing ring; 804. Connecting sleeve; 805. Clamping ball; 806. Punching head. Detailed Implementation

[0025] The technical solutions of the biological sample processing equipment in the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this utility model, and not all embodiments. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art of biological sample processing equipment without creative effort are within the scope of protection of this utility model.

[0026] Please refer to Figures 1 to 4 This utility model provides a leak-proof dried blood spot punch, which aims to solve the problems of easy leakage and loss of dried blood spot samples after punching and the cumbersome replacement of punch heads in existing biological sample processing equipment technology.

[0027] like Figure 1 and Figure 2 As shown, a spill-proof dried blood spot punch includes a stamping module 6, a replacement component 8, a disassembly component 7 for connecting the stamping module 6 and the replacement component 8, and a collection chamber 1. The stamping module 6 provides stamping power. A punching head 806 is detachably mounted on the front end of the replacement component 8. The disassembly component 7 connects the stamping module 6 and the replacement component 8 to achieve overall locking or separation between the replacement component 8 and the stamping module 6. Crucially, the collection chamber 1 is positioned below the stamping path of the punching head 806. The chamber structure of the collection chamber 1 is designed to directly receive and collect dried blood spot samples processed by the punching head 806. The direct positional relationship of the sample that falls off after the punching action ensures structurally that the sample falls into the collection chamber 1, thus fundamentally preventing sample spillage. To facilitate sample storage and retrieval, the collection chamber 1 is also equipped with a door 2, which is connected to the collection chamber 1 by a hinge to close or open the retrieval port of the collection chamber 1. A spill-proof dried blood spot punch also includes a control console 4, which is equipped with a display screen 5 to display the device's operating parameters and status. The control console 4 is also equipped with a button 3, which is located on the control console 4 and electrically connected to the control console 4 for performing quick operations.

[0028] Please refer to Figure 2 The disassembly assembly 7 includes a housing 701, a first spring 702, a pressing plate 703, and a rotating sleeve 704. The pressing plate 703 is movably mounted on the housing 701. The first spring 702 is housed within the housing 701 and abuts against the pressing plate 703 and the rotating sleeve 704. The rotating sleeve 704 is provided with locking teeth 705. Simultaneously, the replacement assembly 8 is correspondingly provided with a locking plate 706 that engages with the locking teeth 705. In the assembled state, the elastic force of the first spring 702 acts on the rotating sleeve 704, causing the locking teeth 705 on the rotating sleeve 704 to lock and engage with the locking plate 706 on the replacement assembly 8, thereby securely fixing the replacement assembly 8. Connected to the stamping module 6; when it is necessary to separate and replace component 8, press the pressing plate 703, the pressing plate 703 moves inward and compresses the first spring 702, the compressed first spring 702 pushes the rotating sleeve 704 to rotate, the rotation of the rotating sleeve 704 causes the locking tooth 705 to disengage from the locking plate 706, thereby releasing the lock on the replacement component 8, and the replacement component 8 can be easily removed; this linkage unlocking structure formed by the pressing plate 703, the first spring 702, the rotating sleeve 704, the locking tooth 705 and the locking plate 706 ensures the connection stability of the replacement component 8 during operation, and at the same time realizes quick disassembly and installation without tools.

[0029] As a preferred embodiment, to achieve quick replacement of the punch head 806, please refer to... Figure 4The replacement component 8 includes a connecting sleeve 804, a retaining ball 805, a second spring 802, a pushing sleeve 801, and a retaining ring 803. The punch head 806 is detachably installed within the connecting sleeve 804. The retaining ball 805 is accommodated within a side wall hole of the connecting sleeve 804. The second spring 802 is sleeved on the outer periphery of the connecting sleeve 804 and applies elastic force to the retaining ball 805, causing a partial protrusion of the retaining ball 805 and locking it into a groove on the outer periphery of the punch head 806, thereby achieving axial locking of the punch head 806. The pushing sleeve 801 is sleeved on the outer periphery of the connecting sleeve 804 and moves axially along the connecting sleeve 804 under the limitation of the retaining ring 803. The inner wall of the pushing sleeve 801 has a… The bottom surface of the punch head 806 contacts the second spring 802. When the punch head 806 needs to be removed, the push sleeve 801 is pushed axially, which compresses the second spring 802 and releases the radial force exerted by the second spring 802 on the retaining ball 805. The retaining ball 805 can then retract inward and disengage from the slot of the punch head 806, at which point the punch head 806 can be removed. When installing a new punch head 806, simply insert it into the connecting sleeve 804. The end of the punch head 806 will push the retaining ball 805 open. After passing the retaining ball 805, under the elastic force of the second spring 802, the retaining ball 805 automatically resets and snaps into the slot of the new punch head 806, completing the quick fixation.

[0030] Working principle: When it is necessary to perform dried blood spot drilling, first open the door 2, place the dried blood spot sample in the designated drilling position in the collection chamber 1, and then set the operation through the control panel 4. The display screen 5 shows the equipment status in real time. Press the button 3 or start the equipment through the control panel 4. After receiving the instruction, the stamping module 6 starts to work, driving the entire replacement component 8 together with the punching head 806 at its front end to perform a downward stamping motion. The punching head 806 penetrates the dried blood spot sample, and the punched sample falls directly into the collection chamber 1 directly below due to gravity. Due to the closed structure of the collection chamber 1, the leakage, loss or contamination of the sample is effectively avoided.

[0031] When the worn punch head 806 needs to be replaced, first press the pressing plate 703 on the disassembly assembly 7. The pressing plate 703 compresses the first spring 702, which in turn pushes the rotating sleeve 704 to rotate, causing the retaining teeth 705 on the rotating sleeve 704 to disengage from the retaining plate 706 on the replacement assembly 8. At this time, the entire housing 701 can be removed from the stamping module 6. Next, push the pushing sleeve 801 on the replacement assembly 8 by hand. Under the limit of the retaining ring 803, the pushing sleeve 801 compresses the second spring 802, releasing the radial thrust of the second spring 802 on the retaining ball 805, allowing the retaining ball 805 to move towards the target. The new punch head 806 retracts inward and disengages from its slot, allowing it to be removed. The new punch head 806 is then inserted into the connecting sleeve 804. The pushing sleeve 801 is released, and the second spring 802 returns to its elasticity, pushing the retaining ball 805 back into the slot of the new punch head 806, thus quickly securing the punch head 806. Finally, the replacement assembly 8 with the new punch head 806 is reinstalled back into the stamping module 6. The pressing plate 703 is released, and the first spring 702 resets, causing the rotating sleeve 704 to rotate in the opposite direction, re-engaging the retaining teeth 705 with the retaining plate 706, allowing the equipment to continue operation. Through the synergistic effect of the disassembly assembly 7 and the replacement assembly 8, this invention solves the problem of the complex and time-consuming replacement process of the punch head 806 in existing biological sample processing equipment technology.

[0032] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions of the biological sample processing equipment described in the foregoing embodiments or make equivalent substitutions for some of the technical features of the biological sample processing equipment. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A spill-proof dried blood spot punch, comprising a stamping module (6) and a replacement assembly (8) fitted with a punch head (806), characterized in that, The spill-proof dried blood spot punch also includes: Collection chamber (1), the collection chamber (1) being disposed below the punching path of the punching head (806), for collecting samples falling after being punched by the punching head (806); and Disassembly assembly (7), which is connected between the stamping module (6) and the replacement assembly (8), is used to lock or release the replacement assembly (8) to the stamping module (6).

2. The spill-proof dried blood spot punch according to claim 1, characterized in that: The collection chamber (1) is provided with a door (2), which is used to close or open the opening for taking out and putting in the collection chamber (1).

3. The spill-proof dried blood spot punch according to claim 1, characterized in that: The disassembly assembly (7) includes a rotating sleeve (704), a pressing plate (703), and a first spring (702); the rotating sleeve (704) is provided with a locking tooth (705), and the replacement assembly (8) is provided with a locking plate (706) that cooperates with the locking tooth (705); when the pressing plate (703) is pressed, it drives the first spring (702) and drives the rotating sleeve (704) to rotate so that the locking tooth (705) disengages from the locking plate (706).

4. A spill-proof dried blood spot punch according to claim 3, characterized in that: The disassembly assembly (7) also includes a housing (701), the pressing plate (703) is movably disposed on the housing (701), and the first spring (702) is housed in the housing (701) and abuts against the pressing plate (703) and the rotating sleeve (704).

5. A spill-proof dried blood spot punch according to claim 1, characterized in that: The replacement assembly (8) includes a connecting sleeve (804), in which the punch head (806) is pluggably installed; the replacement assembly (8) also includes a retaining ball (805), a second spring (802), and a pushing sleeve (801); the second spring (802) applies a spring force to cause the retaining ball (805) to engage in the slot of the punch head (806) to fix the punch head (806), and the pushing sleeve (801) is used to compress the second spring (802) to disengage the retaining ball (805) from the slot.

6. A spill-proof dried blood spot punch according to claim 5, characterized in that: The replacement component (8) further includes a retaining ring (803), and the pushing sleeve (801) is sleeved on the outer periphery of the connecting sleeve (804) and moves axially along the connecting sleeve (804) under the limitation of the retaining ring (803).

7. A spill-proof dried blood spot punch according to claim 1, characterized in that: The spill-proof dried blood spot punch also includes a control console (4) and a display screen (5) set on the control console (4), the display screen (5) being used to display operating parameters and status.

8. A spill-proof dried blood spot punch according to claim 7, characterized in that: The console (4) is also provided with a button (3), which is electrically connected to the console (4).

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