Modular cell culture tubing fixture

Abstract

The utility model discloses a modularization cell culture pipeline fixing device relates to cell culture technical field, the utility model discloses a device body, it includes oppositely arranged first clamping assembly and second clamping assembly, and the first clamping assembly and second clamping assembly define first clamping mouth and second clamping mouth between, be equipped with the clamping assembly of the second clamping mouth inner pipeline fixed on the second clamping assembly, two pressure plates, its fixed connection on the first clamping assembly and second clamping assembly respectively, and the rotation is connected through first pivot between two pressure plates, and the first torsional spring is set up on first pivot. The utility model discloses through the double clamping of first clamping mouth and second clamping mouth, cooperate the clamping assembly on second clamping assembly, can fix the pipeline of different length, specification on the support frame of different size, can avoid its because free hanging or swing and produce winding, reduce the interference that brings to the follow -up cell culture operation and observation because of pipeline confusion.

Description

Technical Field

[0001] This utility model belongs to the field of cell culture, and more specifically, it relates to a fixing device for modular cell culture tubing. Background Technology

[0002] In the fields of biopharmaceutical, cell therapy, and life science research, cell culture is one of the key technological links. With the development of automated and high-throughput cell culture technology, modular cell culture systems have become the mainstream trend in the industry due to their advantages such as flexible combination and efficient management. Such systems usually include multiple culture tanks, pipelines, pumps, valves, and sensors. Each module realizes functions such as culture medium transfer, gas exchange, and sample collection through the pipeline system. However, the pipeline layout in existing cell culture systems is relatively messy, and the connection with the cell culture tank is also relatively complicated, making it difficult to install and maintain, and requiring a lot of manpower and time.

[0003] Chinese patent CN214496266U discloses a tubing arrangement structure for cell culture jars. This device uses grooves to arrange the tubing sequentially, which does not occupy too much space, ensures safe use, and is simple and uncluttered. When installing the tubing, the mounting ring needs to be rotated first, which drives the torsion spring inside the groove to compress it, and at the same time, the slider on the inner wall aligns with the groove. Then, the mounting ring is installed on the mounting block until the slider enters the annular groove from the groove. Then, the mounting ring is released, and the torsion spring will drive the mounting ring to rotate, causing the slider to be misaligned with one end of the groove. The annular groove then locks the slider in place, thus fixing the tubing. However, after the tubing is installed with the mounting ring, some of the tubing is too long to be easily fixed, which can easily cause the tubing to become tangled and messy, affecting subsequent cell culture.

[0004] In view of this, this utility model is proposed. Utility Model Content

[0005] The technical problem to be solved by this utility model is to overcome the shortcomings of the prior art and provide a modular cell culture tubing fixing device, which solves the problems mentioned in the background art.

[0006] To solve the above-mentioned technical problems, the basic concept of the technical solution adopted by this utility model is as follows: A modular cell culture tubing fixing device includes: a device body, which includes a first clamping component and a second clamping component disposed opposite to each other, a first clamping port and a second clamping port being defined between the first clamping component and the second clamping component, and the second clamping component being provided with a clamping component for fixing the tubing in the second clamping port; Two pressure plates are fixedly connected to the first clamping assembly and the second clamping assembly, respectively. The two pressure plates are rotatably connected by a first rotating shaft, and a first torsion spring is sleeved on the first rotating shaft.

[0007] Optionally, the first clamping assembly includes a first plate, a second plate, and a connecting plate. The connecting plate is fixedly installed between the first plate and the second plate, and the second plate is fixedly connected to the pressure plate. Both the first plate and the second plate have an arc-shaped structure.

[0008] Optionally, the second clamping assembly includes a third plate and a fourth plate disposed relative to the first plate and the second plate, the first clamping port being located between the third plate and the first plate, the second clamping port being located between the fourth plate and the second plate, and the clamping assembly being located on the fourth plate.

[0009] Optionally, both the first plate and the third plate are fixedly connected with bonding plates that can be bonded to each other.

[0010] Optionally, a first connecting block and a second connecting block are fixedly connected to the third plate and the fourth plate, respectively. The first connecting block and the second connecting block are rotatably connected by a second rotating shaft. A second torsion spring is sleeved on the second rotating shaft. The second torsion spring has a deformation end and two connecting ends. The two connecting ends are fixedly connected to the first connecting block and the second connecting block, respectively. The deformation end is fixedly connected to the third plate.

[0011] Optionally, the connecting plate is disposed opposite to the fourth plate, and slots are provided through the connecting plate and the fourth plate, a support rod is rotatably connected in the slot, and a clamping pad is fixedly connected to the inner wall of the slot.

[0012] Optionally, the clamping assembly includes: A fixing block is fixedly installed on the fourth plate. An adjusting screw passes through and is threadedly connected to the fixed block. The end of the adjusting screw extends into the second clamping port and is fixedly mounted with a clamping plate, which is positioned relative to the second plate.

[0013] Optionally, a guide rod is movably connected through the fixing block, one end of the guide rod is fixedly connected to the clamping plate, and the other end is fixedly connected to a limiting plate. The fixing block has an indented groove for the limiting plate to move.

[0014] By adopting the above technical solution, the present invention has the following beneficial effects compared with the prior art. Of course, any product implementing the present invention does not necessarily need to achieve all of the following advantages at the same time: By incorporating a first clamping component, a second clamping component, and a clamping component, and through the dual clamping of the first and second clamping ports, combined with the clamping component on the second clamping component, tubing of different lengths and specifications can be fixed on support frames of different sizes. This allows for the adaptation of cell culture tubing of different diameters and materials. In particular, for longer tubing, it can prevent tangling caused by free hanging or swinging, maintain the neat and orderly layout of the cell culture system tubing, and reduce the interference caused by tubing disorder to subsequent cell culture operations and observations. By incorporating a second torsion spring, a first connecting block, and a second connecting block, the second torsion spring enables the third plate to reset when the first clamping port disengages from the support frame rod. This prevents conflict between the first and second clamping ports when clamping support frame rods and pipes of different sizes, increasing the adaptability and versatility of the device. By incorporating a slot and a support rod, the stability of the third plate is improved, preventing it from rotating excessively under the influence of the first torsion spring.

[0015] The specific embodiments of this utility model will be described in further detail below with reference to the accompanying drawings. Attached Figure Description

[0016] The accompanying drawings described below are merely some embodiments. Those skilled in the art can obtain other drawings based on these drawings without any creative effort. In the drawings: Figure 1 This is a schematic diagram of the overall structure of this utility model; Figure 2 This utility model Figure 1 A structural diagram from another perspective; Figure 3 This is a schematic diagram of the clamping assembly of this utility model; Figure 4 This is a schematic diagram of the card slot structure of this utility model; Figure 5 This is a schematic diagram of the structure of the clamping pad of this utility model; Figure 6 This utility model Figure 5 Enlarged structural diagram of point A in the middle; Figure 7 This is a schematic diagram of the structure of the movable groove of this utility model; Figure 8 This is a schematic diagram of the structure of the second torsion spring of this utility model.

[0017] The attached diagram lists the components represented by each number as follows: 1. First clamping port; 2. Second clamping port; 3. Device body; 31. First clamping assembly; 311. First plate; 312. Second plate; 313. Connecting plate; 32. Second clamping assembly; 321. Third plate; 322. Fourth plate; 33. Pressure plate; 4. First rotating shaft; 5. First torsion spring; 6. First buffer pad; 7. Support rod; 8. Guide rod; 9. Clamping assembly; 91. Adjusting screw; 92. Fixing block; 93. Clamping plate; 10. Deformation end; 11. Second buffer pad; 12. Adhesive plate; 13. Slot; 14. Clamping pad; 15. Movable slot; 16. Second rotating shaft; 17. Second torsion spring; 18. First connecting block; 19. Second connecting block; 20. Limiting plate; 21. Connecting end.

[0018] It should be noted that these accompanying drawings and textual descriptions are not intended to limit the scope of the present invention in any way, but rather to illustrate the concept of the present invention to those skilled in the art by referring to specific embodiments. Detailed Implementation

[0019] The present invention will now be described in further detail with reference to the accompanying drawings.

[0020] Please see Figure 1-8 As shown, this embodiment provides a modular cell culture tubing fixing device, including a device body 3, which includes a first clamping component 31 and a second clamping component 32 arranged opposite to each other. A first clamping port 1 and a second clamping port 2 are defined between the first clamping component 31 and the second clamping component 32. The second clamping component 32 is provided with a clamping component 9 for fixing the tubing in the second clamping port 2. Two pressure plates 33 are respectively fixedly connected to the first clamping component 31 and the second clamping component 32. The two pressure plates 33 are rotatably connected by a first rotating shaft 4. A first torsion spring 5 is sleeved on the first rotating shaft 4.

[0021] Specifically, in use, the operator grasps the two pressure plates 33 with their fingers and manually applies force to rotate the first clamping assembly 31 and the second clamping assembly 32 relative to each other along the first rotating shaft 4. At this time, the first torsion spring 5, which is sleeved on the first rotating shaft 4, is compressed and stores energy. When the first clamping port 1 and the second clamping port 2 open to the appropriate size, the cell culture tubing to be fixed is placed in the second clamping port 2, and the first clamping port 1 is placed on the external support frame (support rod 7, etc.). Then, the external force is released, and under the elastic restoring force of the first torsion spring 5, the first clamping assembly 31 and the second clamping assembly 32 automatically rotate towards each other. The first clamping port 1 clamps the main external support frame, while the tubing is initially fixed in the second clamping port 2. Then, by operating the clamping component 9 on the second clamping assembly 32, the tubing is further fixed. Positioning and fastening further enhance the fixation effect and prevent the tubing from tangling due to shaking or contact. When adjusting the tubing layout in the modular cell culture system, manual force is applied again to separate the first clamping component 31 and the second clamping component 32, allowing for convenient disassembly or reinstallation of the tubing. This enables rapid modular reconfiguration and simple operation of the overall structure. Through the dual clamping of the first clamping port 1 and the second clamping port 2, in conjunction with the clamping component 9 on the second clamping component 32, tubing of different lengths and specifications can be fixed on support frames of different sizes. It can accommodate cell culture tubing of different diameters and materials. Especially for longer tubing, it can prevent tangling caused by free hanging or swinging, maintain the neat and orderly layout of the cell culture system tubing, and reduce interference from tubing disorder to subsequent cell culture operations and observations.

[0022] It should be noted that, in this embodiment, buffer pads, such as rubber pads or sponge pads, are fixedly connected to the inner walls of both the first clamping assembly 31 and the second clamping assembly 32. When fixing the pipeline, these buffer pads can effectively disperse pressure, avoid local compression or wear on the pipeline, and reduce problems such as pipeline deformation and rupture caused by improper fixing. This extends the service life of the pipeline and reduces the maintenance cost and contamination risk of the cell culture system. Meanwhile, in this embodiment, the two ends of the first torsion spring 5 abut against the two pressure plates 33 respectively, and the installation method between the first rotating shaft 4 and the two pressure plates 33 is existing technology. Furthermore, this device can be applied to support frame rods that can be fixed by the first clamping port 1. Of course, the shape of the first clamping port 1 can be adjusted according to the actual situation, which will not be described here.

[0023] In this embodiment, as Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5As shown, the first clamping assembly 31 includes a first plate 311, a second plate 312, and a connecting plate 313. The connecting plate 313 is fixedly installed between the first plate 311 and the second plate 312. The second plate 312 is fixedly connected to the pressure plate 33. Both the first plate 311 and the second plate 312 have arc-shaped structures. The second clamping assembly 32 includes a third plate 321 and a fourth plate 322 disposed opposite to the first plate 311 and the second plate 312. The first clamping opening 1 is located between the third plate 321 and the first plate 311. The second clamping port 2 is located between the fourth plate 322 and the second plate 312. The clamping assembly 9 is located on the fourth plate 322. Specifically, the third plate 321 and the fourth plate 322 are arc-shaped structures that match the first plate 311 and the second plate 312. When it is necessary to fix the cell culture tubing, the operator applies external force to make the first clamping assembly 31 and the second clamping assembly 32 rotate around the first rotating shaft 4. The first torsion spring 5 is compressed by force. Because the first plate 311, the second plate 312 and the third plate 321 and the fourth plate 322 are... The components are all arc-shaped. As the assembly rotates, the first clamping port 1 and the second clamping port 2 open, allowing different pipes to be placed inside. Then, when the external force is removed, under the elastic restoring force of the first torsion spring 5, the first plate 311 and the third plate 321 move closer together. At this time, the support frame rod is located inside the first clamping port 1, fixing the device body 3 to the support frame. Simultaneously, the second plate 312 and the fourth plate 322 also move closer together, clamping and fixing the pipes inside the second clamping port 2. The tubing is further secured by the clamping assembly 9 on the fourth plate 322. When the tubing layout needs to be adjusted or the tubing needs to be replaced, external force is applied again to rotate the assembly, and the first clamping port 1 and the second clamping port 2 open, allowing the tubing to be easily disassembled. The whole process is simple to operate and can quickly realize the installation and disassembly of the tubing. The first plate 311, the second plate 312, the third plate 321 and the fourth plate 322 adopt an arc-shaped structure design, which can better fit the circular cell culture tubing and support frame rod.

[0024] In this embodiment, as Figure 1 , Figure 2 , Figure 3 and Figure 4 As shown, both the first plate 311 and the third plate 321 are fixedly connected with bonding plates 12 that can be bonded to each other. Specifically, the bonding plates 12 can significantly increase the stability between the first plate 311 and the third plate 321.

[0025] In this embodiment, as Figure 4 , Figure 5 , Figure 6 and 8As shown, a first connecting block 18 and a second connecting block 19 are fixedly connected to the third plate 321 and the fourth plate 322, respectively. The first connecting block 18 and the second connecting block 19 are rotatably connected by a second rotating shaft 16. A second torsion spring 17 is sleeved on the second rotating shaft 16. The second torsion spring 17 has a deformation end 10 and two connecting ends 21. The two connecting ends 21 are fixedly connected to the first connecting block 18 and the second connecting block 19, respectively. The deformation end 10 is fixedly connected to the third plate 321. Specifically, when the first plate 311 and the third plate 321 clamp and fix the rod on the support frame, the third plate 321 can rotate under the action of the second rotating shaft 16. The second torsion spring 17 can enable the third plate 321 to reset when the first clamping port 1 is disengaged from the support frame rod. This ensures that the first clamping port 1 and the second clamping port 2 will not conflict when clamping support frame rods and pipes of different sizes, increasing the adaptability of the device and improving its versatility.

[0026] In this embodiment, as Figure 1 , Figure 3 , Figure 4 and Figure 5 As shown, the connecting plate 313 is positioned opposite the fourth plate 322. A slot 13 is provided through both the connecting plate 313 and the fourth plate 322. A support rod 7 is rotatably connected within the slot 13, and a clamping pad 14 is fixedly connected to the inner wall of the slot 13. Specifically, in this embodiment, the support rod 7 is rotatably positioned within one set of slots 13, and the support rod 7 can be clamped within the slot 13. When the device is not in use or after the pipeline and support frame have been clamped and fixed, by rotating the support rod 7 into the corresponding slot 13, the support rod 7 is engaged with the fourth plate 322 and the connecting plate 313. 3. The vertical orientation provides support for the fourth plate 322 and the connecting plate 313. This prevents the third plate 321 from rotating significantly due to the action of the first torsion spring 5, thus improving the stability of the third plate 321. The clamping pad 14 can be made of sponge or rubber, etc. The function of the clamping pad 14 is to enhance the clamping ability of the support rod 7. When it is necessary to place the pipeline into the second clamping port 2, the support rod 7 can be rotated into the slot 13. At this time, the support rod 7 is parallel to the connecting plate 313, so that the pipeline can be placed into the second clamping port 2.

[0027] In this embodiment, as Figure 1 , Figure 3 , Figure 4 , Figure 5 and Figure 7As shown, the clamping assembly 9 includes a fixing block 92, which is fixedly mounted on the fourth plate 322. An adjusting screw 91 is threaded through and connected to the fixing block 92. The end of the adjusting screw 91 extends into the second clamping port 2 and is fixedly mounted with a clamping plate 93. The clamping plate 93 is positioned relative to the second plate 312. A guide rod 8 is threaded through and movably connected to the fixing block 92. One end of the guide rod 8 is fixedly connected to the clamping plate 93, and the other end is fixedly connected to a limiting plate 20. The fixing block 92 has a recessed movable groove 15 for the limiting plate 20 to move. Specifically, in this embodiment, the adjusting screw 91 and the guide rod 8 are threaded through and movably mounted on the fourth plate 322. When it is necessary to fix the pipeline in the second clamping port 2, the adjusting screw 91 is rotated. Since the adjusting screw 91 is threadedly connected to the fixing block 92, the adjusting screw 91 will move axially under the action of the threaded transmission, driving... The clamping plate 93 at the end moves closer to the second plate 312. At the same time, the guide rod 8 slides in the movable groove 15 in the fixed block 92, providing guidance for the movement of the clamping plate 93 and preventing the clamping plate 93 from shifting or rotating during movement. This ensures that the clamping plate 93 can smoothly and accurately fit the pipe surface. As the adjusting screw 91 continues to rotate, the clamping plate 93 gradually clamps the pipe, achieving clamping and fixing. When it is necessary to disassemble the pipe, the adjusting screw 91 is rotated in the opposite direction. Under the constraint of the guide rod 8, the clamping plate 93 moves smoothly away from the pipe until the clamping of the pipe is released, making it convenient and quick to disassemble the pipe, thereby improving the applicability of the device. It should be noted that in this embodiment, the diameter of the pipe must be smaller than the diameter of the second clamping port 2 when the device is not in use. The limiting plate 20 plays a limiting role, and the diameter of the limiting plate 20 is larger than the diameter of the guide rod 8.

[0028] Working principle: During use, the operator grasps the two pressure plates 33 with their fingers and manually applies force to rotate the first clamping assembly 31 and the second clamping assembly 32 relative to each other along the first rotating shaft 4. At this time, the first torsion spring 5, which is sleeved on the first rotating shaft 4, is compressed and stores energy. When the first clamping port 1 and the second clamping port 2 open to the appropriate size, the cell culture tubing to be fixed is placed in the second clamping port 2, and the first clamping port 1 is placed on the external support frame (support rod 7, etc.). Then, the external force is released, and under the elastic restoring force of the first torsion spring 5... The first clamping assembly 31 and the second clamping assembly 32 automatically rotate towards each other. The first clamping port 1 clamps the main external support frame, while the pipeline is initially fixed within the second clamping port 2. Then, when it is necessary to fix the pipeline within the second clamping port 2, the adjusting screw 91 is rotated. Since the adjusting screw 91 is threadedly connected to the fixing block 92, under the action of threaded transmission, the adjusting screw 91 will move axially, driving the clamping plate 93 at the end to move closer to the second plate 312. At the same time, the guide rod 8 slides in the movable groove 15 within the fixing block 92, thus clamping the pipeline. The movement of the holding plate 93 provides guidance, preventing the clamping plate 93 from shifting or rotating during movement, ensuring that the clamping plate 93 can smoothly and accurately fit the surface of the tubing. As the adjusting screw 91 continues to rotate, the clamping plate 93 gradually clamps the tubing, achieving secondary positioning and fastening of the tubing, further enhancing the fixing effect, and preventing the tubing from tangling due to shaking or contact. When adjusting the tubing layout in the modular cell culture system, manual force is applied again to separate the first clamping component 31 and the second clamping component 32, allowing for convenient disassembly or reinstallation of the tubing, achieving rapid modular reconfiguration. The overall structure is simple to operate. Through the double clamping of the first clamping port 1 and the second clamping port 2, in conjunction with the clamping component 9 on the second clamping component 32, tubing of different lengths and specifications can be fixed on support frames of different sizes. It can adapt to cell culture tubing of different diameters and materials. Especially for longer tubing, it can prevent tangling due to free hanging or swinging, maintaining the neat and orderly layout of the cell culture system tubing, and reducing interference from tubing disorder to subsequent cell culture operations and observations.

[0029] This utility model is not limited to the above-described embodiments. Anyone should know that structural changes made under the guidance of this utility model, and any technical solutions that are the same as or similar to this utility model, fall within the protection scope of this utility model. Technical aspects, shapes, and structures not described in detail in this utility model are all publicly known technologies.

Claims

1. A fixing device for modular cell culture tubing, characterized in that, include: The device body (3) includes a first clamping component (31) and a second clamping component (32) disposed opposite to each other. A first clamping port (1) and a second clamping port (2) are defined between the first clamping component (31) and the second clamping component (32). The second clamping component (32) is provided with a clamping component (9) for fixing the pipe inside the second clamping port (2). Two pressure plates (33) are fixedly connected to the first clamping assembly (31) and the second clamping assembly (32) respectively. The two pressure plates (33) are rotatably connected by a first rotating shaft (4). A first torsion spring (5) is sleeved on the first rotating shaft (4).

2. The modular cell culture tubing fixing device according to claim 1, characterized in that, The first clamping assembly (31) includes a first plate (311), a second plate (312) and a connecting plate (313). The connecting plate (313) is fixedly installed between the first plate (311) and the second plate (312). The second plate (312) is fixedly connected to the pressure plate (33). Both the first plate (311) and the second plate (312) are arc-shaped structures.

3. The modular cell culture tubing fixing device according to claim 2, characterized in that, The second clamping assembly (32) includes a third plate (321) and a fourth plate (322) disposed relative to the first plate (311) and the second plate (312), the first clamping port (1) being located between the third plate (321) and the first plate (311), the second clamping port (2) being located between the fourth plate (322) and the second plate (312), and the clamping assembly (9) being located on the fourth plate (322).

4. The modular cell culture tubing fixing device according to claim 3, characterized in that, Both the first plate (311) and the third plate (321) are fixedly connected with bonding plates (12) that can be bonded to each other.

5. A fixing device for modular cell culture tubing according to claim 3, characterized in that, A first connecting block (18) and a second connecting block (19) are fixedly connected to the third plate (321) and the fourth plate (322), respectively. The first connecting block (18) and the second connecting block (19) are rotatably connected by a second rotating shaft (16). A second torsion spring (17) is sleeved on the second rotating shaft (16). The second torsion spring (17) has a deformation end (10) and two connecting ends (21). The two connecting ends (21) are fixedly connected to the first connecting block (18) and the second connecting block (19), respectively. The deformation end (10) is fixedly connected to the third plate (321).

6. The modular cell culture tubing fixing device according to claim 3, characterized in that, The connecting plate (313) is positioned relative to the fourth plate (322). The connecting plate (313) and the fourth plate (322) are respectively provided with slots (13) through them. A support rod (7) is rotatably connected in the slot (13). A clamping pad (14) is fixedly connected to the inner wall of the slot (13).

7. The modular cell culture tubing fixing device according to claim 3, characterized in that, The clamping assembly (9) includes: A fixing block (92) is fixedly installed on the fourth plate (322); An adjusting screw (91) is threaded through and connected to the fixed block (92). The end of the adjusting screw (91) extends into the second clamping port (2) and is fixedly mounted with a clamping plate (93). The clamping plate (93) is positioned relative to the second plate (312).

8. A fixing device for modular cell culture tubing according to claim 7, characterized in that, A guide rod (8) is movably connected through the fixed block (92). One end of the guide rod (8) is fixedly connected to the clamping plate (93), and the other end is fixedly connected to the limiting plate (20). The fixed block (92) has an indented groove (15) for the limiting plate (20) to move.

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