Homogenizer for biological medicine

Abstract

The utility model belongs to homogenizer technical field especially is a kind of homogenizer of biological medicine.The utility model includes connecting stand plate, the closed top cover plate of the one side installation of connecting stand plate top and the homogenizing cylinder of the lower portion of closed top cover plate is provided, still include: the bottom of closed top cover plate is installed with stirring shaft body, and the upper half of stirring side shaft is fixedly connected with stirring shaft body;Shaft body slot is opened in the end face of stirring side shaft close to stirring shaft body, and stirring vane is installed between stirring side shaft and stirring shaft body, and the surface of stirring shaft body is longitudinally equidistant and is provided with the adjusting perforated part for the height adjustment of stirring vane.The utility model designs the design of adjustable longitudinal spacing of stirring vane, can be flexibly adjusted according to material characteristics (viscosity, solid content) and processing demand (liquid level height, homogenization precision).

Description

Technical Field

[0001] This utility model relates to the field of homogenizer technology, specifically a homogenizer for biomedicine. Background Technology

[0002] In the fields of food processing, biomedicine, and chemical industry, homogenizers are the core equipment for refining and uniformly mixing materials. As a key component that directly acts on the materials, the structural design of its stirring shaft directly determines the homogenization efficiency, material compatibility, and ease of equipment maintenance. Currently, most existing homogenizers use an integrated fixed structure for their stirring shafts or rigidly connect them to the transmission system through bolts, couplings, or other means.

[0003] The existing stirring shafts have a fixed longitudinal installation position, making it impossible to adjust the longitudinal spacing according to material characteristics (such as viscosity and solid content) or processing requirements (such as avoiding bottom sedimentation for small batches of materials and increasing the stirring coverage area for high-viscosity materials). For example, when processing small batches of biopharmaceutical materials with low liquid levels (such as stem cell culture medium), the fixed spacing of the stirring shaft can easily lead to uneven homogenization because it cannot reach the material at the bottom of the chamber. On the other hand, when processing high-viscosity slurries (such as jams in the food industry and coatings in the chemical industry), the excessive spacing can result in insufficient stirring shear force, requiring extended homogenization time and reducing production efficiency.

[0004] Therefore, we propose a homogenizer for biomedicine to solve the above problems. Utility Model Content

[0005] (a) Technical problems to be solved

[0006] To address the shortcomings of existing technologies, this invention provides a homogenizer for biopharmaceutical applications. It solves the problem mentioned in the background section where the longitudinal installation position of the existing stirring shaft is fixed, making it impossible to adjust the longitudinal spacing according to material characteristics (such as viscosity and solid content) or processing requirements (such as avoiding bottom sedimentation for small batches of materials and increasing the stirring coverage area for high-viscosity materials). For example, when processing small batches of biopharmaceutical materials with low liquid levels (such as stem cell culture medium), a fixed-spacing stirring shaft may fail to reach the bottom of the chamber, leading to uneven homogenization. Conversely, when processing high-viscosity slurries (such as jams in the food industry and coatings in the chemical industry), excessive spacing results in insufficient stirring shear force, necessitating extended homogenization time and reduced production efficiency.

[0007] (II) Technical Solution

[0008] To achieve the above objectives, this utility model specifically adopts the following technical solution:

[0009] A homogenizer for biomedicine includes a connecting column plate, a closed top cover plate installed on one side of the top of the connecting column plate, and a homogenizing cylinder disposed below the closed top cover plate. It also includes a stirring shaft body installed at the bottom of the closed top cover plate, and the upper half of the stirring side shaft is fixedly connected to the stirring shaft body.

[0010] The shaft body has a slot on the end face of the stirring side shaft near the stirring shaft body, and stirring blades are installed between the stirring side shaft and the stirring shaft body. The surface of the stirring shaft body has longitudinally spaced adjustment holes for adjusting the height of the stirring blades.

[0011] Furthermore, a connecting side block is provided on one side of the stirring blade, and a slider that slides along the groove of the shaft is fixed on the surface of the connecting side block.

[0012] Furthermore, an assembly plate is fixedly provided at the end of the connecting side block away from the slider, and the surface of the assembly plate is provided with multi-faceted holes, and an assembly plug that is inserted and connected to the multi-faceted holes is fixedly provided at the center of one side of the stirring blade.

[0013] Furthermore, a mounting back plate is fixedly provided at the rear end of the connecting side block, and a reinforcing plate that is in contact with the surface of the stirring shaft body is fixedly provided at the end of the mounting back plate.

[0014] Furthermore, the surface of the reinforcing plate is provided with perforations that are adapted to the adjustment perforation section, and a round hole is provided at the end of the stirring blade away from the assembly plug.

[0015] Furthermore, a connecting piece is provided between the stirring blade and the stirring shaft body, and a cylindrical plug that can be inserted into the round hole is fixed on the surface of the connecting piece, and a through hole adapted to the adjustment through hole is also provided on the surface of the connecting piece.

[0016] (III) Beneficial Effects

[0017] Compared with the prior art, this utility model provides a homogenizer for biomedicine, which has the following beneficial effects:

[0018] This invention features an adjustable longitudinal spacing design for the stirring blades. This allows for flexible adjustment of the blade spacing relative to the bottom of the homogenization chamber based on material characteristics (viscosity, solid content) and processing requirements (liquid level, homogenization accuracy). When processing small batches of materials at low liquid levels, the blade spacing is lowered to cover the material at the bottom of the chamber, preventing uneven homogenization caused by sedimentation. When processing high-viscosity materials, the spacing is raised to increase the longitudinal coverage of the stirring and shearing action, improving shearing efficiency. The stirring blades employ a convenient disassembly structure, facilitating individual deep cleaning of the blades and preventing material residue in the connection gaps. This design meets the requirements of the biopharmaceutical and food industries and also facilitates subsequent maintenance and replacement. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of the structure of this utility model;

[0020] Figure 2 This is an enlarged structural schematic diagram of the stirring blade of this utility model;

[0021] Figure 3 This is a side view of the stirring blade of this utility model;

[0022] Figure 4 This is a diagram showing the separation of the cylindrical plug and the stirring blade of this utility model.

[0023] In the diagram: 1. Connecting column plate; 2. Closing top cover plate; 3. Homogenizing cylinder; 4. Stirring side shaft; 5. Stirring shaft body; 6. Stirring blades; 7. Grooved shaft body; 8. Connecting side block; 9. Mounting back plate; 10. Assembly plate; 11. Assembly plug; 12. Connecting piece; 13. Cylindrical plug; 14. Reinforcing plate; 15. Adjustment perforation. Detailed Implementation

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0025] Example

[0026] like Figure 1-4 As shown, an embodiment of this utility model proposes a homogenizer for biomedicine, including a connecting column plate 1, a closed top cover plate 2 installed on one side of the top of the connecting column plate 1, and a homogenizing cylinder 3 disposed below the closed top cover plate 2. The closed top cover plate 2 is adapted to the homogenizing cylinder 3. After the homogenizing cylinder 3 is rotated to a vertical position, the longitudinal movement of the closed top cover plate 2 can press against the top opening of the homogenizing cylinder 3. At this time, the structure connected to the bottom of the closed top cover plate 2 will extend into the homogenizing cylinder 3. The driving of the closed top cover plate 2 and the rotation of the homogenizing cylinder 3 are conventional structural designs of homogenizers and will not be described in detail.

[0027] The difference is that the originally vertical stirring shaft is designed as a stirring shaft body 5, and a stirring side shaft 4 is horizontally fixed at the top of the stirring shaft body 5. The stirring side shaft 4 is bent so that the end faces upward and is located on one side of the stirring shaft body 5. Stirring blades 6 can be installed between the stirring shaft body 5 and the stirring side shaft 4. Stirring is completed by installing stirring blades 6.

[0028] A shaft slot 7 is provided at the end of the stirring side shaft 4. A connecting side block 8 is provided on one side of the stirring blade 6, and a slider is fixed on the surface of the connecting side block 8 that slides along the groove of the shaft slot 7. The position and height of the connecting side block 8 can be adjusted by sliding the slider in the groove of the shaft slot 7. An assembly plate 10 is fixed on the end of the connecting side block 8 away from the slider, and a polygonal hole is provided on the surface of the assembly plate 10. An assembly plug 11 that is inserted into the polygonal hole is fixed on the center of one side of the stirring blade 6. In actual assembly, the assembly plug 11 on one side of the stirring blade 6 is inserted into the polygonal hole on the assembly plate 10. The stirring blade 6 presents different angles depending on the insertion angle. At the same time, the height of the stirring blade 6 can be adjusted by adjusting the height of the connecting side block 8.

[0029] A mounting back plate 9 is fixedly provided at the rear end of the connecting side block 8, and a reinforcing plate 14 is fixedly provided at the end of the mounting back plate 9, which is in contact with the surface of the stirring shaft body 5. The surface of the reinforcing plate 14 has a through hole adapted to the adjustment through hole 15, and a round hole is provided at the end of the stirring blade 6 away from the mounting plug 11. A connecting piece 12 is provided between the stirring blade 6 and the stirring shaft body 5, and a cylindrical plug 13 that can be inserted into the round hole is fixedly provided on the surface of the connecting piece 12. The surface of the connecting piece 12 also has a through hole adapted to the adjustment through hole 15. In actual assembly, the cylindrical plug 13 is inserted into the round hole, and the mounting plugs 11 on both sides of the stirring blade 6 and the cylindrical plug 13 provide support for the stirring blade 6. After the cylindrical plug 13 is installed, the through holes at the connecting piece 12 and the reinforcing plate 14 are aligned with the adjustment through hole 15. The surface of the stirring shaft body 5 is longitudinally aligned with the adjustment through hole 15. The stirring blades 6 are provided with equal-spaced adjustment perforations 15 for height adjustment, thus having multiple longitudinally spaced positioning mounting points. The connecting plate 12, stirring shaft body 5, and reinforcing plate 14 are then locked synchronously with bolts to complete the reinforcement of the mounting back plate 9 and the stirring blades 6. The spacing between the stirring blades 6 and the bottom of the homogenization chamber can be flexibly adjusted according to the material characteristics, viscosity, solid content, processing requirements, liquid level, and homogenization accuracy. When processing low-liquid-level, small-batch materials, the spacing of the stirring blades 6 can be lowered to cover the material at the bottom of the chamber, avoiding uneven homogenization caused by sedimentation. When processing high-viscosity materials, the spacing can be raised to increase the longitudinal coverage of stirring and shearing, improving shearing efficiency. The stirring blades 6 adopt a convenient disassembly structure, which facilitates deep cleaning of the stirring blades 6 individually to avoid material residue in the connection gaps, meeting the requirements of the biopharmaceutical and food fields, and also facilitating subsequent maintenance and replacement.

[0030] Finally, it should be noted that the above description is merely a preferred embodiment of this utility model and is not intended to limit the utility model. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A homogenizer for biomedicine, comprising a connecting column plate (1), a closed top cover plate (2) installed on one side of the top of the connecting column plate (1), and a homogenizing cylinder (3) disposed below the closed top cover plate (2), characterized in that, Also includes: The stirring shaft body (5) is installed at the bottom of the closed top cover plate (2), and the upper half of the stirring side shaft (4) is fixedly connected to the stirring shaft body (5). The shaft body has a slot (7) on the end face of the stirring side shaft (4) near the stirring shaft body (5), and stirring blades (6) are installed between the stirring side shaft (4) and the stirring shaft body (5). The surface of the stirring shaft body (5) is provided with adjusting perforations (15) at equal intervals in the longitudinal direction for adjusting the height of the stirring blades (6).

2. The homogenizer for biomedicine according to claim 1, characterized in that: The stirring blade (6) has a connecting side block (8) on one side, and the surface of the connecting side block (8) is fixed with a slider that slides in the groove (7) along the shaft.

3. The homogenizer for biomedicine according to claim 2, characterized in that: The connecting side block (8) is fixed with an assembly plate (10) at one end away from the slider, and the surface of the assembly plate (10) is provided with a multi-faceted hole. An assembly plug (11) is fixed at the center of one side of the stirring blade (6) and is connected to the multi-faceted hole.

4. The homogenizer for biomedicine according to claim 3, characterized in that: The rear end of the connecting side block (8) is fixedly provided with a mounting back plate (9), and the end of the mounting back plate (9) is fixedly provided with a reinforcing plate (14) that is in contact with the surface of the stirring shaft body (5).

5. A homogenizer for biomedicine according to claim 4, characterized in that: The surface of the reinforcing plate (14) is provided with perforations that are compatible with the adjustment perforation part (15), and the end of the stirring blade (6) away from the assembly plug (11) is provided with a round hole.

6. A homogenizer for biomedicine according to claim 1, characterized in that: A connecting piece (12) is provided between the stirring blade (6) and the stirring shaft body (5), and a cylindrical plug (13) that can be inserted into the round hole is fixed on the surface of the connecting piece (12), and a through hole that is adapted to the adjustment through hole (15) is also provided on the surface of the connecting piece (12).

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