Probe storage aid and memory assembly

Abstract

The utility model discloses a kind of auxiliary device and memory component of detecting object storage, belong to detecting object storage equipment technical field.The device aims to solve the problem of incomplete reconstitution caused by sticking to container cover or high inner wall due to static electricity and shaking of detecting object small ball in the transport process.The technical scheme points are that a film fixed plug is used, which is composed of a rigid support ring and a brittle sealing film.The outer diameter of the lower end of the support ring is suitable for clamping on the internal shoulder of the storage, thereby separating the inner cavity of the container into an upper cavity and a lower ball storage cavity.The brittle sealing film covers the lower end port of the support ring and leaves a pressure prevention gap between the detecting object small ball.The device can effectively limit the displacement of the small ball, prevent it from jumping or sticking to a high place, and ensure that the detecting object can be fully reconstituted at the bottom of the container when in use, mainly used for the auxiliary fixing and limiting of detecting object storage in medical immunodetection.

Description

Technical Field

[0001] This utility model belongs to the technical field of detection object storage devices, and more specifically, this utility model relates to an auxiliary device and memory component for a detection object storage device. Background Technology

[0002] In the field of medical immunology, especially in fluorescence immunochromatography, labeled antibodies are often stored as solid probe beads using vacuum low-temperature freeze-drying technology. Each bead is approximately 3.9 mm in diameter, and 1-3 beads are dispensed into each probe storage unit for later use. The probe storage unit is usually a plastic tube, wider at the top and narrower at the bottom, tapering from the middle downwards. The outer diameter of the upper part is 9.7 mm, the lower part is 7.7 mm, and the overall height of the plastic tube is approximately 24.8 mm. To use, open the cap of the plastic tube, then use a pipette to add 100-300 μL of diluent to the tube to dissolve the probe. The liquid level should be approximately 6.8 mm from the bottom. Then add the sample (75-50-30-10 μL, the amount varies depending on the test), mix well, and then take 75 μL for testing.

[0003] During transportation, static electricity can easily be generated due to friction between the probe balls or between the probe and the inner wall of the memory, causing the probe to adhere to the outer cover of the memory or the inner wall of the container (see...). Figure 3 (See the existing phenomenon diagram). This phenomenon causes the added quantitative sample diluent to fail to fully contact the probe adhering to a high position during testing, resulting in incomplete redissolution of the probe and thus affecting the accuracy of the test results; the small ball adhering to the container lid is prone to flying out when the lid is opened, also affecting the test. Therefore, a memory auxiliary tool is needed that can fix the position of the probe and prevent it from shifting due to electrostatics. Utility Model Content

[0004] One object of this invention is to solve at least the aforementioned defects and to provide at least the advantages described below.

[0005] This invention provides an auxiliary device for a detector storage device, which solves the problem that detector balls adhere to the container lid or inner wall high up due to static electricity and shaking during transportation.

[0006] This utility model provides an auxiliary device for a detector storage device. The detector storage device is a tube with a large inner diameter at the top and a small inner diameter at the bottom. An accommodating cavity for accommodating a small ball of detector is formed inside. The inner wall of the accommodating cavity forms an annular shoulder at the junction of the upper and lower parts. The auxiliary device includes a thin-film fixing plug, which consists of a rigid support ring and a brittle sealing film covering the lower port of the support ring. The outer diameter of the support ring is larger than the inner diameter of the lower accommodating cavity of the probe storage and smaller than or equal to the inner diameter of the upper accommodating cavity, so that the thin-film fixing plug can be inserted from the tube opening and abut against the shoulder, thereby dividing the accommodating cavity into an upper cavity and a lower ball storage cavity. A pressure-resistant gap is reserved between the brittle sealing film and the probe ball placed at the bottom of the ball storage cavity.

[0007] Preferably, the brittle sealing film is an aluminum foil composite material or a medical polymer film with a hydrophobic surface treatment.

[0008] Preferably, the support ring is made of plastic and has an interference fit with the shoulder of the probe storage.

[0009] Preferably, a brittle sealing film is heat-sealed to the lower end port of the support ring.

[0010] Preferably, the upper outer side of the support ring is provided with a flange for locking and limiting, the outer diameter of the flange being less than or equal to the inner diameter of the probe storage tube opening, so that the flange can be embedded inside the tube opening; the distance between the lower surface of the flange and the shoulder of the probe storage is configured such that when the upper end face of the flange abuts against or is slightly lower than the lower end of the outer cover of the tube opening, the lower port of the support ring abuts against the shoulder.

[0011] Preferably, one end of a traction rope is fixed to the upper end of the support ring, and the other end of the traction rope extends to the opening of the pipe.

[0012] Preferably, the side wall of the support ring is provided with a guide groove that runs through it from top to bottom, and one end of a traction rope is fixed to the bottom of the support ring or the lower part of the side wall, and the other end of the rope passes through the guide groove and extends to the pipe opening.

[0013] Preferably, the free end of the traction rope is provided with a pull ring or marker ball for easy gripping; the inner wall of the guide groove is smoothly transitioned to avoid cutting the traction rope.

[0014] This utility model also provides a detector storage assembly, which includes the above-mentioned auxiliary device for the detector storage and a tubular detector storage, wherein the opening of the detector storage is provided with an outer cover that can be opened and closed.

[0015] This utility model has at least the following beneficial effects: First, this invention features a thin-film retaining plug that abuts against the shoulder of the memory device. The brittle sealing film forms a physical barrier, confining the small ball within the lower storage cavity. This effectively prevents displacement and jumping, ensuring the probe is fully reconstituted at the bottom of the container during use. It is primarily used for auxiliary fixation and positioning of probe storage devices in medical immunoassays. The pre-reserved pressure-resistant gap ensures the film does not directly press on the small ball, preventing breakage due to compression. This device requires no alteration to the existing memory device's main structure, utilizing its inherent shape for positioning; it is highly versatile and easy to install.

[0016] Secondly, the support ring of this invention is made of plastic and forms an interference fit with the shoulder of the storage device. The plastic material has a certain degree of elasticity, making it easy to insert and press against the shoulder. The interference fit ensures that it will not loosen due to vibration during transportation, thus improving the reliability of the device.

[0017] Third, a flange is provided on the upper outer side of the support ring for engagement with the outer cover, enhancing the stability of the overall structure. This invention also features a traction rope to facilitate user removal of the film retainer from the storage after use, avoiding direct contact contamination or operational inconvenience. The guide groove design allows the traction rope to directly pull the interference fit at the lower end of the support ring; the smooth transition of the guide groove's inner wall prevents cutting or jamming during pull-out, making operation smoother. A pull ring or marker ball is also provided at the free end of the traction rope to increase operational convenience and identification, making it easier for users to grip and pull out.

[0018] Other advantages, objectives and features of this invention will be partly apparent from the following description, and partly understood by those skilled in the art through study and practice of this invention. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of one embodiment in which the auxiliary device for the detector storage of the present invention is placed inside the storage. Figure 2 This is an enlarged schematic diagram of the auxiliary device for the detector storage of the present invention; Figure 3 This is a diagram illustrating the existing phenomenon of probes adhering to the outer cover of a memory or the inner wall of a container in the prior art. Among them, the outer cover is 1; the upper part of the detector storage is 2; the lower part of the detector storage is 3; the detector storage is 4; the ball storage cavity is 5; the detector ball is 6; the brittle sealing film is 7; the support ring is 8; the film fixing plug is 9; the plastic bead is 10; the flange is 11; and the traction rope is 12. Detailed Implementation

[0020] The present invention will be further described in detail below with reference to the embodiments, so that those skilled in the art can implement it based on the description.

[0021] It should be noted that, unless otherwise specified, the experimental methods described in the following embodiments are conventional methods, and the reagents and materials described are commercially available. In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "setting" should be interpreted broadly. For example, they can refer to fixed connection or setting, detachable connection or setting, or integral connection or setting. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances. The terms "lateral," "longitudinal," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model and simplifying the description. They do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0022] Figure 1-2 An embodiment of an auxiliary device for a detector storage device is shown. The detector storage device 4 is a plastic tube with a larger inner diameter at the top and a smaller inner diameter at the bottom. Specifically, the upper part 2 of the detector storage device has a larger inner diameter, and the lower part 3 has a smaller inner diameter. An accommodating cavity is formed inside, and a ring-shaped shoulder is naturally formed at the junction of the upper and lower parts. This auxiliary device includes a thin-film retainer 9, which consists of a rigid plastic support ring 8 and a brittle sealing film 7. The brittle sealing film can be made of aluminum foil composite material and is tightly sealed to the lower port of the support ring using a thermoforming process. The outer diameter of the lower end of the support ring can be designed to be 7.5 mm, which is larger than the inner diameter of the lower accommodating cavity of the storage device (e.g., 7.2 mm); the outer diameter of the upper end of the support ring can be designed to be 8.8 mm, which is slightly smaller than the inner diameter of the upper accommodating cavity of the storage device (e.g., 9.2 mm). Thus, the thin-film retainer can be inserted from the tube opening and pressed against the shoulder by the interference fit between its outer diameter and the inner wall of the cavity containing the shoulder. During installation, it is necessary to ensure that there is a pressure-resistant gap of at least 0.5 mm between the brittle sealing membrane and one to three probe balls 6 that are pre-placed at the bottom of the ball storage cavity 5. This gap can ensure that the membrane will not compress the balls.

[0023] During operation, the installed memory is transported with the probe pellets confined within the storage chamber. Due to the physical barrier of the brittle sealing membrane, the pellets cannot jump out due to static electricity or shaking and adhere to the container lid or inner wall. When the user needs to use the probe, first open the outer cover 1, then use a pipette tip to draw 150 μL of diluent, insert the tip into the tube and gently press downwards to puncture the brittle sealing membrane, adding the diluent into the storage chamber. The liquid flows into the storage chamber, submerging and beginning to dissolve the probe pellets. Afterward, the user can directly pull the upper edge of the support ring by hand, or use tweezers to insert into the tube and grasp the support ring to remove the membrane retainer from the memory, allowing for sample addition and subsequent mixing.

[0024] Alternatively, the entire membrane fixing plug can be removed from the memory first, and then the diluent can be added with a pipette tip to dissolve the probe pellet.

[0025] This embodiment effectively limits the movement range of the probe ball through a detachable mechanical isolation structure, solving the problem of displacement caused by electrostatic adsorption during transportation, which affects resolution.

[0026] In another embodiment, the brittle sealing film can be selected from common pharmaceutical aluminum foil composite materials, such as PTP pharmaceutical aluminum foil, which has a certain tensile strength and can be punctured by a pipette tip. Another option is to use a medical polymer film with a hydrophobic surface treatment, such as a superhydrophobic film on a PMMA substrate.

[0027] In another embodiment, the support ring can be made of polypropylene plastic. Its outer diameter tolerance can be controlled between -0.05 mm and +0.02 mm, while the inner diameter tolerance at the memory shoulder is controlled between ±0.03 mm, thus achieving an interference fit of approximately 0.02 to 0.08 mm between the two. This interference fit generates sufficient friction to ensure that the diaphragm retainer is not easily dislodged or displaced from the shoulder when subjected to vibration, thereby stably maintaining its limiting function.

[0028] In another embodiment, the connection between the brittle sealing film and the lower port of the support ring can be achieved using a thermoforming process. During operation, the film is placed over the port of the support ring, and a certain pressure and temperature are applied through a heated sealing mold, causing the heat-sealing adhesive layer on the film surface to melt and fuse with the plastic support ring. After cooling, a strong connection is formed, ensuring that it can be operated as a single, integrated component.

[0029] In another embodiment, to more precisely control the installation depth and position of the membrane retainer, a flange 11 can be designed on the upper outer side of the support ring. The outer diameter of this flange can be set to 9.1 mm, slightly smaller than or equal to the inner diameter of the probe storage tube opening (e.g., 9.2 mm). The distance between the lower surface of the flange and the lower port of the support ring is configured such that when the upper end face of the flange abuts against or is slightly below the lower end of the outer cap of the tube opening, the lower port of the support ring is stably abutting against the shoulder. At this point, the brittle sealing membrane and the ball form the required pressure-resistant gap, stably maintaining its limiting function.

[0030] In another embodiment, to facilitate the removal of the membrane fixing plug after use, one end of a traction rope can be fixed to the upper end of the support ring, and the other end of the traction rope extends to the tube opening.

[0031] Alternatively, a through-groove can be created on the side wall of the support ring. The width of the groove can be 1 mm. A traction rope, which can be made of thin nylon thread, is fixed at one end to the bottom side wall of the support ring, and the other end passes upward through the guide groove and extends to the top of the tube opening. During operation, before or after adding the diluent, the user can easily remove the entire membrane retainer from the probe storage by pinching the free end of the traction rope with their fingers and pulling upward.

[0032] In another embodiment, to further enhance ease of operation, a small knot or a miniature plastic bead 10 can be tied to the free end of the traction rope 12 as a marker ball. This increases the recognizability and friction for finger gripping, making it easier to pick up. Simultaneously, if a guide groove is provided, its inner and outer edges should be rounded, with a radius of curvature not less than 0.2 mm, to ensure that the groove opening does not cut or wear the traction rope during pulling, thus preventing breakage.

[0033] In another embodiment, the present invention also discloses a detector storage assembly, including an auxiliary device for the detector storage shown above, and a tubular detector storage unit. The opening of the detector storage unit is fitted with an outer cover, which is hinged to the opening (the cover and the tube body are integrally formed, and the connection part is flexible, allowing for a flip-top opening and closing action). When closed, the protruding ring of the outer cover is embedded inside the opening, achieving a tight seal through an interference fit. The assembly is completed before transportation by placing the detector pellets at the bottom of the storage cavity, then placing the thin film fixing plug against the shoulder of the storage unit, and finally closing the outer cover. The lower end of the outer cover abuts against or even presses against the upper surface of the flange, forming a complete, ready-to-use product.

[0034] Although the embodiments of this utility model have been disclosed above, they are not limited to the applications listed in the specification and embodiments. It can be applied to various fields suitable for this utility model. Other modifications can be easily made by those skilled in the art.

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