A microneedle device

Abstract

This utility model relates to the field of oral medical device technology, specifically to a microneedle device. The microneedle device provided by this utility model includes a first microneedle mechanism, a second microneedle mechanism, and a delivery mechanism. The first microneedle mechanism includes a base and a plurality of first microneedles. The base has a first liquid storage chamber, and the plurality of first microneedles are evenly distributed on the base, with the inner cavity of each first microneedle communicating with the first liquid storage chamber. When using the first microneedle mechanism, because the plurality of first microneedles are evenly distributed on the base, the spacing between adjacent first microneedles is basically the same. Therefore, the uniformity of drug injection is higher, and the efficiency is high due to the simultaneous injection of multiple first microneedles.

Description

Technical Field

[0001] This utility model relates to the field of oral medical device technology, specifically to a microneedle device. Background Technology

[0002] In some localized precision treatments for periodontitis and peri-implantitis, microneedles are used to inject medication into the area requiring treatment.

[0003] Currently, common microneedle devices include syringes and single microneedles. The single microneedle is inserted into the area requiring treatment, and the medication is injected into the designated location through the syringe.

[0004] However, microneedle devices like those mentioned above, due to their single microneedle design, are prone to poor drug distribution when injected into the gingival papilla or other areas requiring treatment, affecting the treatment effect and resulting in low efficiency. Utility Model Content

[0005] (a) The problem to be solved by this utility model is that, due to the use of a single microneedle design, the drug distribution is poor when injected into the gingival papilla area, which affects the treatment effect and is inefficient.

[0006] (II) Technical Solution This utility model provides a microneedle device, which includes a first microneedle mechanism, a second microneedle mechanism and a pushing mechanism; The first microneedle mechanism includes a base and a plurality of first microneedles; The base is provided with a first liquid storage cavity, and a plurality of first microneedles are evenly distributed on the base, and the inner cavity of each first microneedle is connected to the first liquid storage cavity. The second microneedle mechanism includes a roller and a plurality of second microneedles; The roller is provided with a second liquid storage chamber, and a plurality of second microneedles are evenly distributed on the side wall of the roller, and the inner cavity of each second microneedle is connected to the second liquid storage chamber. The first microneedle mechanism is detachably connected to the pushing mechanism so that the pushing mechanism pushes the drug solution into the first liquid storage chamber; or, the second microneedle mechanism is detachably connected to the pushing mechanism so that the pushing mechanism pushes the drug solution into the second liquid storage chamber.

[0007] According to one embodiment of the present invention, the second microneedle mechanism further includes an arc-shaped protective plate, which is disposed on one side of the roller.

[0008] According to one embodiment of the present invention, the microneedle device further includes a positioning plate, and a plurality of positioning holes are provided on one side of the positioning plate. The positioning holes correspond one-to-one with the first microneedles, and the diameter of the positioning holes is larger than the outer diameter of the first microneedles.

[0009] According to one embodiment of the present invention, the bottom of the positioning plate is provided with an adhesive layer.

[0010] According to one embodiment of the present invention, the first microneedle mechanism includes a first connecting tube, one end of which is connected to the base, and the other end of which is interference-fitted with the liquid outlet of the pushing mechanism.

[0011] According to one embodiment of the present invention, the first connecting tube includes a first tube portion and a first needle seat connected to each other. The first tube portion is connected to the base, and the first needle seat is interference-fitted with the liquid outlet of the pushing mechanism.

[0012] According to one embodiment of the present invention, the second microneedle mechanism includes a second connecting tube, one end of which is rotatably connected to the roller, and the other end of which is interference-fitted with the liquid outlet of the pushing mechanism.

[0013] According to one embodiment of the present invention, the second connecting tube includes a second tube section, a third tube section, and a second needle seat connected in sequence. The second tube section and the third tube section are perpendicular to each other. One end of the second tube section away from the third tube section is rotatably connected to the roller. The second needle seat and the liquid outlet of the pushing mechanism are interference-fitted.

[0014] According to one embodiment of the present invention, the base is triangular in shape.

[0015] According to one embodiment of the present invention, the side length of the base is between 0.8mm and 5mm.

[0016] The beneficial effects of this utility model are: When using the first microneedle mechanism, the outlets of the first microneedle mechanism and the delivery mechanism are connected, allowing the delivery mechanism to push the medication into the first reservoir. Since multiple first microneedles are evenly distributed on the base, with approximately the same spacing between adjacent first microneedles, the uniformity of medication injection is higher, and the simultaneous injection of multiple first microneedles results in high efficiency. When using the second microneedle mechanism, the outlets of the second microneedle mechanism and the delivery mechanism are connected, allowing the delivery mechanism to push the medication into the second reservoir. Since multiple second microneedles are evenly distributed on the outer wall of the roller, the uniformity of medication injection is even higher when the roller rolls and multiple second microneedles puncture, resulting in better treatment efficacy. Furthermore, the choice between the first or second microneedle mechanism based on the actual treatment location further enhances efficiency. Attached Figure Description

[0017] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0018] Figure 1 A three-dimensional structural diagram of the microneedle device provided in the embodiment of this utility model; Figure 2 A front view of the first microneedle mechanism and positioning plate provided in an embodiment of this utility model; Figure 3 A front view of the second microneedle mechanism provided in an embodiment of this utility model; Figure 4 A three-dimensional structural diagram of the positioning plate provided in an embodiment of this utility model.

[0019] Icons: 1. First microneedle mechanism; 11. Base; 12. First microneedle; 13. First connecting tube; 131. First tube section; 132. First needle seat; 2. Second microneedle mechanism; 21. Roller; 22. Second microneedle; 23. Arc-shaped protective plate; 24. Second connecting tube section; 241. Second tube section; 242. Third tube section; 243. Second needle seat; 3. Pushing mechanism; 31. Nipple; 32. Sleeve; 33. Push rod; 4. Positioning plate; 41. Positioning hole. Detailed Implementation

[0020] The technical solution of this utility model will be clearly and completely described below with reference to the embodiments. Obviously, the described embodiments are only some embodiments of this utility model, not all embodiments. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of this utility model.

[0021] like Figures 1-4 As shown, one embodiment of the present invention provides a microneedle device, including a first microneedle mechanism 1, a second microneedle mechanism 2, and a pushing mechanism 3; The first microneedle mechanism 1 includes a base 11 and a plurality of first microneedles 12; The base 11 is provided with a first liquid storage chamber, and a plurality of first microneedles 12 are evenly distributed on the base 11, and the inner cavity of each first microneedle 12 is connected to the first liquid storage chamber. The second microneedle mechanism 2 includes a roller 21 and a plurality of second microneedles 22; The roller 21 is provided with a second liquid storage chamber, and multiple second microneedles 22 are evenly distributed on the side wall of the roller 21. The inner cavity of each second microneedle 22 is connected to the second liquid storage chamber. The first microneedle mechanism 1 is detachably connected to the pushing mechanism 3 so that the pushing mechanism 3 pushes the liquid into the first liquid storage chamber; or, the second microneedle mechanism 2 is detachably connected to the pushing mechanism 3 so that the pushing mechanism 3 pushes the liquid into the second liquid storage chamber.

[0022] Specifically, when using the first microneedle mechanism 1, the outlet of the first microneedle mechanism 1 and the push mechanism 3 are connected, allowing the push mechanism 3 to push the medication into the first reservoir. Since multiple first microneedles 12 are evenly distributed on the base 11, and the spacing between adjacent first microneedles 12 is basically the same, the uniformity of medication injection is higher, and the efficiency is high due to the simultaneous injection of multiple first microneedles 12. When using the second microneedle mechanism 2, the outlet of the second microneedle mechanism 2 and the push mechanism 3 are connected, allowing the push mechanism 3 to push the medication into the second reservoir. Since multiple second microneedles 22 are evenly distributed on the outer wall of the roller 21, the uniformity of medication injection is higher and the treatment effect is better when the roller 21 rolls and multiple second microneedles 22 are inserted. Furthermore, the first microneedle mechanism 1 or the second microneedle mechanism 2 can be selected for treatment according to the actual treatment location, resulting in higher efficiency.

[0023] According to one embodiment of this utility model, the base 11 is triangular in shape, specifically, the base 11 is an equilateral triangle with a side length between 0.5mm and 10mm, preferably 0.8mm. Multiple first microneedles 12 are of the same length, each 2mm, and the bevel angle of the tip of each first microneedle 12 is 30°, suitable for patients with an average gingival papilla width of 1.2-1.8mm. It should be noted that the base 11 can also be rectangular or other shapes.

[0024] Preferably, the number of the first microneedles 12 can be between 9 and 25, depending on actual needs.

[0025] The first microneedle 12 is made of 316L medical-grade stainless steel. It should be noted that the first microneedle 12 can be selected from either an ultra-fine array (the diameter of the first microneedle 12 is 50-80μm, suitable for liquid drug injection, such as 0.1% etimicin solution) or a conventional coarse array (the diameter of the first microneedle 12 is 300-400μm, matching the specifications of insulin needles, suitable for gel-like drug injection, such as 2% minocycline gel). This allows for flexible selection based on actual needs, better conforming to the gingival papilla morphology, and the first microneedle mechanism 1 avoids the problem of drug overflowing onto adjacent surfaces due to excessive pressure during traditional single microneedle injection.

[0026] According to one embodiment of this utility model, the roller 21 has a diameter between 1.5mm and 10mm and a length between 1mm and 5mm. The diameter of the roller 21 is preferably one of four specifications: 1.5mm, 2mm, 3mm, and 5mm. Along the circumference of the roller 21, twelve second microneedles 22 are evenly distributed on the sidewall of the roller 21. Each second microneedle 22 is 1mm long. The needle body of the second microneedles 22 can be made of biodegradable polylactic acid (PLA). The needle tip can be an ultra-fine array (the diameter of the second microneedles 22 is 50-80μm, suitable for liquid drug injection) or a conventional coarse array (the diameter of the second microneedles 22 is 300-400μm, matching the specifications of insulin needles, suitable for gel drug injection). During rolling drug delivery, the second microneedles 22 form microchannels through point contact, allowing the drug to be evenly distributed with the rolling motion. This is suitable for drug delivery to the gums, mucosa, etc. The first microneedle mechanism 1 or the second microneedle mechanism 2 can be selected for treatment depending on the actual treatment location.

[0027] According to one embodiment of the present invention, the second microneedle mechanism 2 further includes an arc-shaped protective plate 23, which is disposed on one side of the roller 21. The outer surface of the arc-shaped protective plate 23 is arc-shaped, without sharp edges, and is unlikely to scratch the patient. The arc-shaped protective plate 23 is connected by a connector and a second connecting tube 24.

[0028] The curved protective plate 23 has a smooth surface and is made of medical-grade polyetheretherketone (PEEK) 3D printed material, such as... Figure 3 As shown, the projection of the roller 21 can fall completely into the arc-shaped protective plate 23. During small field of view operation, due to the natural coverage of the buccal mucosa on the dental side, the arc-shaped protective plate 23 can be used to protect the mucosa on the opposite side of the treatment site throughout the treatment process, preventing the second microneedle 22 from puncturing the mucosa on the opposite side.

[0029] According to one embodiment of the present invention, the microneedle device further includes a positioning plate 4. A groove is provided on one side of the positioning plate 4. The function of the groove is to ensure that only the edge of the positioning plate 4 contacts the gingival papilla, avoiding contact of the entire surface, which would result in low stability. A plurality of positioning holes 41 communicating with the groove are provided on the other side. The positioning holes 41 correspond one-to-one with the first microneedle 12. The diameter of the positioning holes 41 is larger than the outer diameter of the first microneedle 12.

[0030] According to one embodiment of the present invention, the bottom of the positioning plate 4 is provided with an adhesive layer, which is a pressure-sensitive adhesive layer.

[0031] When using the first microneedle mechanism 1 for treatment, the positioning plate 4 is fixed to the gingival papilla by the pressure-sensitive adhesive layer. After the fixation is completed, multiple first microneedles 12 are inserted into the corresponding positioning holes 41. Force is applied to make multiple first microneedles 12 pierce into the gingival papilla. Since the positioning is pre-positioned by the positioning plate 4, it can prevent the first microneedle 12 from deviating from its piercing position due to hand tremors or other reasons.

[0032] Preferably, a positioning plate 4 of the corresponding specification is selected according to the size of the gingival papilla (the size includes height and base width) to adapt to different base widths.

[0033] The pushing mechanism 3 is a spiral push rod micro-injector, preferably a spiral push rod micro-injector with an internal capacity of 2mm-5mm. The spiral push rod micro-injector includes a sleeve 32, a plunger, a push rod 33 and a nipple 31. One end of the sleeve 32 is connected to the nipple 31. A plunger is sealed inside the sleeve 32. A push rod 33 is connected to one side of the plunger. The plunger is moved by the push rod 33. The nipple 31 is the outlet of the pushing mechanism 3. When the first needle seat 132 is connected to the nipple 31 by interference fit, the medicine can be pushed into the first reservoir. When the second needle seat 243 is connected to the nipple 31, the medicine can be pushed into the second reservoir.

[0034] According to one embodiment of the present invention, the first microneedle mechanism 1 includes a first connecting tube 13, one end of which is connected to a base 11, and the other end of which is interference-fitted with the liquid outlet of the pushing mechanism 3.

[0035] Specifically, the first connecting tube 13 includes a first tube portion 131 and a first needle seat 132 connected to each other. The first tube portion 131 is connected to the base 11, and the first needle seat 132 is press-fitted with the nipple 31.

[0036] The first tube 131 can be configured as a straight line, an L-shape, or an arc shape.

[0037] According to one embodiment of the present invention, the second microneedle mechanism 2 includes a second connecting tube 24, one end of which is rotatably connected to a roller 21, and the other end of which is interference-fitted with the liquid outlet of the pushing mechanism 3.

[0038] Specifically, the second connecting tube 24 includes a second tube section 241, a third tube section 242, and a second needle seat 243 connected in sequence. The second tube section 241 and the third tube section 242 are perpendicular to each other. The end of the second tube section 241 away from the third tube section 242 is rotatably connected to the roller 21. The second needle seat 243 and the nipple 31 are interference-fitted. The axis of the second tube section 241 coincides with the axis of the roller 21.

[0039] Since the second tube 241 is rotatably connected to the roller 21, when the doctor pushes the medicine into the second reservoir by holding the push mechanism 3, the push mechanism 3 can also be moved at the same time, so that the roller 21 rolls along its axis. Pushing the roller 21, the second microneedle 22 is inserted to a depth of 1mm, and can perform crisscrossing linear rolling in the treatment area, increasing the number of pores on the mucosal surface and increasing the amount of drug permeation.

[0040] In another embodiment, the second tube 241 is directly fixedly connected to the roller 21. The angle between the roller 21 and the gingival papilla surface is changed by the doctor's hand-held pushing mechanism 3, causing the roller 21 to roll. The purpose of this embodiment does not deviate from the design concept of this utility model, and therefore, it should fall within the protection scope of this utility model.

[0041] When used for injections into the oral mucosa, lips, buccal mucosa, or lingual / palatal gingiva, the second microneedle mechanism 2 can be used. It is suitable for injections over larger areas or for surface penetration of the drug. When used in areas with smaller areas and higher precision requirements, such as the gingival papilla, the first microneedle mechanism 1 can be used for injection.

[0042] The first microneedle mechanism 1 can be interference-fitted with the outlet of the push mechanism 3 via the first needle seat 132, and the second microneedle mechanism 2 can be interference-fitted with the outlet of the push mechanism 3 via the second needle seat 243, making replacement more convenient and faster, with a replacement time of ≤10 seconds. Using this microneedle device, the doctor's operation time is reduced to 30 seconds per case (compared to 60 seconds for a traditional single needle), and the drug is evenly distributed, significantly improving treatment accuracy.

[0043] In the description of this utility model, it should be noted that the terms "upper" and "lower," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model. Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0044] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "connection" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the connection within two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances. Furthermore, in the description of this utility model, unless otherwise stated, "a plurality of" means two or more.

[0045] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A microneedle device, characterized in that, It includes a first microneedle mechanism (1), a second microneedle mechanism (2), and a push mechanism (3); The first microneedle mechanism (1) includes a base (11) and a plurality of first microneedles (12); The base (11) is provided with a first liquid storage cavity, and a plurality of first microneedles (12) are evenly distributed on the base (11), and the inner cavity of each first microneedle (12) is connected to the first liquid storage cavity; The second microneedle mechanism (2) includes a roller (21) and a plurality of second microneedles (22); The roller (21) is provided with a second liquid storage chamber, and a plurality of second microneedles (22) are evenly distributed on the side wall of the roller (21), and the inner cavity of each second microneedle (22) is connected to the second liquid storage chamber; The first microneedle mechanism (1) is detachably connected to the pushing mechanism (3) so that the pushing mechanism (3) pushes the liquid medicine into the first liquid storage chamber, or the second microneedle mechanism (2) is detachably connected to the pushing mechanism (3) so that the pushing mechanism (3) pushes the liquid medicine into the second liquid storage chamber.

2. The microneedle device according to claim 1, characterized in that, The second microneedle mechanism (2) also includes an arc-shaped protective plate (23), which is located on one side of the roller (21).

3. The microneedle device according to claim 1, characterized in that, The microneedle device also includes a positioning plate (4), on one side of which are a plurality of positioning holes (41), each of which corresponds to the first microneedle (12), and the diameter of the positioning hole (41) is greater than the outer diameter of the first microneedle (12).

4. A microneedle device according to claim 3, characterized in that, The bottom of the positioning plate (4) is provided with an adhesive layer.

5. A microneedle device according to claim 1, characterized in that, The first microneedle mechanism (1) includes a first connecting tube (13), one end of which is connected to the base (11), and the other end is interference-fitted with the liquid outlet of the pushing mechanism (3).

6. A microneedle device according to claim 5, characterized in that, The first connecting tube (13) includes a first tube section (131) and a first needle seat (132) connected to each other. The first tube section (131) is connected to the base (11), and the first needle seat (132) is interference-fitted with the liquid outlet of the pushing mechanism (3).

7. A microneedle device according to claim 1, characterized in that, The second microneedle mechanism (2) includes a second connecting tube (24), one end of which is rotatably connected to the roller (21), and the other end is interference-fitted with the liquid outlet of the pushing mechanism (3).

8. A microneedle device according to claim 7, characterized in that, The second connecting tube (24) includes a second tube section (241), a third tube section (242), and a second needle seat (243) connected in sequence. The second tube section (241) and the third tube section (242) are perpendicular to each other. The end of the second tube section (241) away from the third tube section (242) is rotatably connected to the roller (21). The second needle seat (243) and the liquid outlet of the pushing mechanism (3) are interference-fitted.

9. A microneedle device according to claim 1, characterized in that, The base (11) is triangular in shape.

10. A microneedle device according to claim 9, characterized in that, The side length of the base (11) is between 0.8mm and 5mm.

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