A multi-channel pipetting aid for the preparation of adipose-derived stem cells

Abstract

This invention discloses a multi-channel pipetting aid for the preparation of adipose-derived stem cells, belonging to the technical field of pipetting aids. It includes a device body with an internal adjustment assembly. The invention utilizes a rotating rocker to drive a lead screw to rotate within a placement groove. During the rotation of the lead screw, a slider moves along the lead screw axis, which in turn moves a horizontal plate synchronously. The horizontal plate, through a tilted groove design, allows multiple sets of circular shafts to open and close synchronously. This causes the circular shafts to slide, moving a vertical plate horizontally along a limiting axis. The limiting axis ensures stable and non-deviation-prone movement of the vertical plate. Multiple vertical plates are connected by a component to synchronously adjust the spacing of the pipetting tips, allowing for flexible adjustment of the tip spacing without requiring device replacement or switching to a single channel, thus avoiding operational interruptions.

Description

Technical Field

[0001] This utility model relates to the field of pipetting assistance device technology, specifically a multi-channel pipetting assistance device for the preparation of adipose stem cells. Background Technology

[0002] In the process of preparing adipose-derived stem cells, the role of the multi-channel pipetting aid device revolves around four core needs: improving operational efficiency, ensuring cell viability and purity, reducing the risk of contamination, and ensuring experimental reproducibility. It is deeply adapted to the characteristics of the entire process of preparing adipose-derived stem cells, from material collection and processing, separation and purification to culture and expansion, and is a key piece of equipment for standardized and large-scale preparation of adipose-derived stem cells.

[0003] Existing multichannel pipetting aids for adipose stem cell preparation have a fixed distance between pipette tips. When the distance between the pipette tips and the container for liquid collection is different, single-channel operation or multiple repositioning is required, which reduces efficiency, increases the risk of cross-contamination, and accumulates errors, which is not conducive to high throughput and standardization.

[0004] To address this, a multi-channel pipetting aid device for the preparation of adipose-derived stem cells is proposed. Utility Model Content

[0005] In order to overcome the shortcomings of the prior art and solve at least one of the technical problems mentioned in the background art, this utility model proposes a multi-channel pipetting aid device for the preparation of adipose stem cells.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a multi-channel pipetting aid for the preparation of adipose stem cells, comprising a device body, wherein an adjustment component is provided inside the device body; The adjustment assembly includes a mounting plate fixedly connected to the inner wall of the device body. The mounting plate has a placement groove inside, and a lead screw is installed inside the placement groove. A slider passes through the lead screw, and a horizontal plate is fixedly connected to one side of the slider. Multiple sets of sliding grooves are formed on the surface of the horizontal plate, and a round shaft is slidably connected inside each of the multiple sets of sliding grooves. A vertical plate is fixedly connected to one end of each round shaft. Multiple sets of limiting shafts pass through one side of the vertical plate and are fixedly connected to the inner wall of the mounting plate. A rocker arm is fixedly connected to the top of the lead screw, and a connecting assembly is fixedly connected to the surface of the vertical plate. A pipette tip is installed at the bottom end of the connecting assembly.

[0007] Preferably, a positioning plate is fixedly connected to the bottom of the placement slot, and a bearing is fixedly connected to the top of the positioning plate. The bottom of the lead screw is fixedly connected to the inner ring of the bearing. The positioning plate 441 supports and positions the bearing 442. Then, under the action of the bearing 442, the rotation range of the lead screw 44 can be limited to prevent it from shifting or moving during rotation, which would affect the subsequent use effect.

[0008] Preferably, the inner wall of the mounting plate has limit grooves on both sides. The horizontal plate slides inside the limit grooves. The limit grooves 412 constrain the horizontal plate to slide only in a straight line, suppressing tilting and torsion, ensuring that the displacement of each channel is consistent, and reducing the risk of cross-contamination and wall adhesion.

[0009] Preferably, the connecting assembly includes a fixing block, one side of which is fixedly connected to the surface of the vertical plate. A first locking block is fixedly connected to the bottom of the fixing block, and a second locking block is engaged with the bottom of the first locking block. The bottom of the second locking block is fixedly connected to the top of the pipette tip. When it is necessary to disassemble the pipette tip 2, the protrusion on the surface of the second locking block 33 engages with the groove inside the first locking block 32 through the first locking block 32 and the second locking block 33, and the pipette tip 2 can be disassembled by moving it, which is convenient for subsequent replacement.

[0010] Preferably, a gasket is fixedly connected to the bottom of the fixing block, and one side of the gasket is fixedly connected to the top of the first locking block. By using the gasket, the sealing performance is consistent each time the block is installed and removed, reducing liquid residue and contamination.

[0011] Compared with the prior art, the beneficial effects of this utility model are: 1. This utility model uses a rotating rocker arm to drive a lead screw to rotate within a placement groove. During the rotation of the lead screw, a slider is driven to move along the lead screw axis, thereby causing the horizontal plate to move synchronously. The horizontal plate, through the inclined design of the slide groove, can drive multiple sets of round shafts to open and close synchronously. This allows the round shafts to drive the vertical plate to move horizontally along the limiting axis during sliding. Under the action of the limiting axis, the movement of the vertical plate is ensured to be smooth and without deviation. The multiple sets of vertical plates are connected by a component to synchronously adjust the spacing of the pipette tips, allowing for flexible adjustment of the tip spacing without the need to change the device or switch to a single channel, thus avoiding operational interruptions. Attached Figure Description

[0012] Figure 1 This is a three-dimensional structural diagram of the present invention; Figure 2 This is a schematic diagram showing the structural separation of this utility model; Figure 3 This is a partial structural schematic diagram of the present invention; Figure 4 This is a schematic diagram of the installation of the adjustment component structure of this utility model; Figure 5 This is a schematic diagram of the connection component structure installation of this utility model.

[0013] In the diagram: 1. Equipment body; 2. Pipette tip; 3. Connecting assembly; 31. Fixing block; 32. First locking block; 33. Second locking block; 4. Adjusting assembly; 41. Mounting plate; 411. Placement slot; 412. Limiting slot; 42. Limiting shaft; 43. Vertical plate; 44. Lead screw; 441. Positioning plate; 442. Bearing; 45. Rocker arm; 46. Horizontal plate; 47. Slide groove; 48. Round shaft; 49. Slider. Detailed Implementation

[0014] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and should not be construed as limiting the present invention.

[0015] The embodiments of this utility model will be described below based on its overall structure.

[0016] Please see Figure 1 - Figure 5 A multi-channel pipetting aid for the preparation of adipose stem cells includes a device body 1, and an adjustment component 4 is provided inside the device body 1; The adjustment assembly 4 includes a mounting plate 41, which is fixedly connected to the inner wall of the device body 1. The mounting plate 41 has a placement groove 411 inside, and a lead screw 44 is installed inside the placement groove 411. The lead screw 44 passes through a slider 49. A horizontal plate 46 is fixedly connected to one side of the slider 49. Multiple sets of sliding grooves 47 are opened on the surface of the horizontal plate 46. A round shaft 48 is slidably connected inside each of the multiple sets of sliding grooves 47. A vertical plate 43 is fixedly connected to one end of the round shaft 48. Multiple sets of limiting shafts 42 pass through one side of the vertical plate 43. The multiple sets of limiting shafts 42 are fixedly connected to the inner wall of the mounting plate 41. A rocker arm 45 is fixedly connected to the top of the lead screw 44. A connecting assembly 3 is fixedly connected to the surface of the vertical plate 43. A pipette tip 2 is installed at the bottom of the connecting assembly 3.

[0017] The rocker arm 45 can be used to rotate the lead screw 44 within the placement groove 411. During the rotation of the lead screw 44, the slider 49 can be driven to move along the axis of the lead screw 44, thereby causing the horizontal plate 46 to move synchronously. The horizontal plate 46, through the inclined design of the slide groove 47, can drive multiple sets of circular shafts 48 to open and close synchronously. This allows the circular shafts 48 to drive the vertical plate 43 to move horizontally along the limiting shaft 42 during the sliding process. Then, under the action of the limiting shaft 42, the vertical plate 43 is ensured to move smoothly without deviation. The multiple sets of vertical plates 43 can be connected by the connecting component 3 to synchronously adjust the spacing of the pipette tips 2. The spacing of the pipette tips can be flexibly adjusted without changing the device or switching to a single channel, thus avoiding operation interruption.

[0018] Please see Figure 1 and Figure 5A positioning plate 441 is fixedly connected to the bottom of the placement slot 411, and a bearing 442 is fixedly connected to the top of the positioning plate 441. The bottom of the lead screw 44 is fixedly connected to the inner ring of the bearing 442. Limiting grooves 412 are opened on both sides of the inner wall of the mounting plate 41. The horizontal plate 46 slides inside the limiting grooves 412. The connecting assembly 3 includes a fixing block 31. One side of the fixing block 31 is fixedly connected to the surface of the vertical plate 43. A first locking block 32 is fixedly connected to the bottom of the fixing block 31. A second locking block 33 is engaged with the bottom of the first locking block 32. The bottom of the second locking block 33 is fixedly connected to the top of the pipette tip 2. A gasket is fixedly connected to the bottom of the fixing block 31. One side of the gasket is fixedly connected to the top of the first locking block 32. The positioning plate 441 supports and positions the bearing 442. Under the action of the bearing 442, the rotation range of the lead screw 44 can be limited to prevent it from shifting or moving during rotation, which would affect the subsequent use effect. The limiting groove 412 is used to constrain the horizontal plate 46 to slide only in a straight line, suppressing tilting and torsion, ensuring consistent displacement of each channel, and reducing the risk of cross-contamination and wall adhesion. When it is necessary to disassemble the pipette tip 2, the first locking block 32 and the second locking block 33 are used to make the protrusion on the surface of the second locking block 33 engage with the groove inside the first locking block 32, and the pipette tip 2 can be disassembled by moving it, which is convenient for subsequent replacement. The use of gaskets ensures consistent sealing during each assembly and disassembly, reducing liquid residue and contamination.

[0019] The working principle is as follows: A rotating rocker arm 45 drives a lead screw 44 to rotate within the placement groove 411. During the rotation of the lead screw 44, a slider 49 moves along the axis of the lead screw 44, which in turn moves the horizontal plate 46 synchronously. The horizontal plate 46, through the inclined design of the sliding groove 47, can drive multiple sets of circular shafts 48 to open and close synchronously. This allows the circular shafts 48 to move the vertical plate 43 horizontally along the limiting shaft 42 during sliding. Under the action of the limiting shaft 42, the vertical plate 43 moves smoothly without deviation. Multiple sets of vertical plates 43 are connected by the connecting assembly 3 to synchronously adjust the spacing of the pipette tips 2, allowing for flexible adjustment of the tip spacing without changing the device or switching to a single channel, thus avoiding operational interruptions. The positioning plate 441 supports and positions the bearing 442. Under the action of the bearing 442, the rotation range of the lead screw 44 is limited to prevent it from shifting or moving during rotation, which would affect the subsequent use effect. The limiting groove 412 constrains the horizontal plate 46 to slide only in a straight line, suppressing tilting and torsion, ensuring consistent displacement of each channel, and reducing the risk of cross-contamination and wall adhesion. When it is necessary to disassemble the pipette tip 2, the first locking block 32 and the second locking block 33 are used to make the protrusion on the surface of the second locking block 33 engage with the groove inside the first locking block 32, and the pipette tip 2 can be disassembled by moving it, which is convenient for subsequent replacement. The use of gaskets ensures consistent sealing during each assembly and disassembly, reducing liquid residue and contamination.

[0020] Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A multi-channel pipetting aid for the preparation of adipose-derived stem cells, comprising a device body (1), characterized in that: An adjustment component (4) is provided inside the device body (1); The adjustment component (4) includes a mounting plate (41), which is fixedly connected to the inner wall of the device body (1). The mounting plate (41) has a placement groove (411) inside, and a lead screw (44) is installed inside the placement groove (411). The lead screw (44) passes through a slider (49). A horizontal plate (46) is fixedly connected to one side of the slider (49). Multiple sets of sliding grooves (47) are opened on the surface of the horizontal plate (46). A round shaft (48) is slidably connected inside each of the multiple sets of sliding grooves (47). A vertical plate (43) is fixedly connected to one end of the round shaft (48). Multiple sets of limiting shafts (42) pass through one side of the vertical plate (43). The multiple sets of limiting shafts (42) are fixedly connected to the inner wall of the mounting plate (41). A rocker arm (45) is fixedly connected to the top of the lead screw (44). A connecting component (3) is fixedly connected to the surface of the vertical plate (43). A pipette tip (2) is installed at the bottom of the connecting component (3).

2. The multi-channel pipetting aid device for preparing adipose-derived stem cells according to claim 1, characterized in that: The bottom of the placement slot (411) is fixedly connected to a positioning plate (441), the top of the positioning plate (441) is fixedly connected to a bearing (442), and the bottom of the lead screw (44) is fixedly connected to the inner ring of the bearing (442).

3. The multi-channel pipetting aid device for preparing adipose-derived stem cells according to claim 2, characterized in that: Limiting grooves (412) are provided on both sides of the inner wall of the mounting plate (41), and the horizontal plate (46) slides inside the limiting grooves (412).

4. The multi-channel pipetting aid device for preparing adipose-derived stem cells according to claim 3, characterized in that: The connecting component (3) includes a fixing block (31), one side of which is fixedly connected to the surface of the vertical plate (43), and a first locking block (32) is fixedly connected to the bottom of the fixing block (31). A second locking block (33) is engaged with the bottom of the first locking block (32), and the bottom of the second locking block (33) is fixedly connected to the top of the pipette tip (2).

5. The multi-channel pipetting aid device for preparing adipose-derived stem cells according to claim 4, characterized in that: A gasket is fixedly connected to the bottom of the fixing block (31), and one side of the gasket is fixedly connected to the top of the first locking block (32).

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