An inspection apparatus

Abstract

The utility model discloses a kind of test equipment, including main frame, the main frame is set using gantry type upper / lower split structure, the main frame is box structure, the middle position of the main frame is provided with fixed isolation mesa, the upper space of the main frame is provided with first horizontal module and the longitudinal module connected with the first horizontal module, the first horizontal module can be moved along the horizontal direction of the main frame, the longitudinal module moves along the vertical direction of the main frame, two through passageways are fixed on the fixed isolation mesa, two hollow beaker baskets for placing beaker are fixed in the passageway, the position below the fixed isolation mesa of the main frame is also provided with second horizontal module, separator and ultrasonic cleaning tank are respectively provided on the second horizontal module.

Description

Technical Field

[0001] This utility model belongs to the field of testing equipment technology, and specifically relates to a testing device. Background Technology

[0002] Magnetic bead separation technology is a molecular biology separation technique that utilizes the affinity binding of surface-modified magnetic particles to biomolecules or cells for separation. It enables efficient enrichment of targets for separation or detection, and is a convenient, rapid, highly recoverable, and selective method. The application of magnetic bead separation technology in biology began in the late 1970s, and it has already yielded remarkable research results in molecular biology, cell biology, immunology, microbiology, and biochemistry.

[0003] To meet the requirements of cell separation, existing cell separation devices use magnetic bead separation technology for cell detection experiments. In the implementation of related technologies, strong magnetic racks are commonly used for operation. Since strong magnetic racks ensure that multiple different cell sample solutions can be separated simultaneously under the same magnetic conditions, most of the work of adding liquid, stirring and sonicating, separating, and removing waste liquid is done manually. In mass production, this is time-consuming, wastes human resources, and is costly.

[0004] In view of the above factors, this utility model provides a testing device that is simple to operate. Each operation procedure can be composed of several program blocks, and the speed and frequency are adjustable, making it convenient for practical operation and improving work efficiency. Utility Model Content

[0005] The purpose of this invention is to provide an inspection device to solve the problems mentioned in the background art.

[0006] The purpose of this utility model is achieved through the following technical solution: an inspection device, including a main frame, the main frame adopts a gantry-type upper / lower split structure, the main frame is a box structure, a fixed isolation platform is provided in the middle position of the main frame, and a first horizontal module and a vertical module connected to the first horizontal module are provided in the upper space of the main frame.

[0007] The first transverse module is capable of moving horizontally along the main frame, and the longitudinal module is capable of moving vertically along the main frame.

[0008] Two through-holes are fixedly opened on the fixed isolation platform, and two hollow beaker baskets for placing beakers are fixedly installed in the through-holes.

[0009] A second horizontal module is also provided below the fixed isolation platform on the main frame. The second horizontal module is provided with a separator and an ultrasonic cleaning tank.

[0010] Furthermore, the upper front and rear ends of the main frame are connected to the first double doors by hinges, and the lower front and rear ends of the main frame are connected to the second double doors by hinges. The second double doors are folding doors, which are symmetrically arranged, and each folding door includes two door leaves that are hinged to each other. The relative positions of the second double doors are slidably connected to the upper and lower edges of the lower part of the main frame.

[0011] Furthermore, the first transverse module includes a first drive motor and a lead screw shaft connected to the first drive motor, one end of which is connected to a bearing seat on the inner wall of the main frame;

[0012] The first transverse module also includes a linear guide slider connected to the lead screw shaft, and a connecting back plate is fixedly provided on the linear guide slider.

[0013] Furthermore, a longitudinal module is fixedly disposed on the connecting back plate, and the longitudinal module includes at least 3 sets;

[0014] Each of the longitudinal modules includes a fixed frame and a second drive motor mounted on the fixed frame. The second drive motor is connected to a longitudinal lead screw shaft, and the other end of the longitudinal lead screw shaft is connected to a bearing seat on the fixed frame.

[0015] Furthermore, an L-shaped linear guide slider is connected to the longitudinal lead screw shaft, and each set of the longitudinal module's linear guide slider is equipped with a liquid suction pipe, a liquid addition pipe, and a stirrer;

[0016] Each set of vertical modules consists of a suction tube, a liquid addition tube, and a stirrer, from left to right, with two liquid addition tubes provided.

[0017] Furthermore, the second transverse module includes a third drive motor and a second transverse lead screw shaft connected to the third drive motor, with the other end of the second transverse lead screw shaft connected to a bearing seat on the main frame;

[0018] The second transverse module also includes two sets of symmetrical support frames, which are bolted to the bottom of the main frame;

[0019] The support frame is provided with a slide rail, which cooperates with the slider set on the positioning plate. The second transverse lead screw shaft is connected to the nut block, and the nut block is fixedly connected to the positioning plate.

[0020] Furthermore, a lifting device is fixedly installed on the positioning plate, and a separator and an ultrasonic cleaning tank are installed on the lifting device;

[0021] The lifting device is either a hydraulic lifting device or an electric cylinder lifting device.

[0022] Furthermore, a display control screen is also provided on the main frame. The display control screen is electrically connected to a controller located at the position of a microcontroller or PLC. The controller is electrically connected to a first horizontal module, a second horizontal module, and a vertical module.

[0023] Furthermore, the bottom of the main frame is equipped with casters, which allow it to be moved as needed during use.

[0024] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0025] This invention utilizes a combination of a first horizontal module, a second horizontal module, and a vertical module to sequentially and repeatedly perform the processes of adding liquid, stirring and sonicating, separating, and aspirating waste liquid in a beaker. The process is controlled by a microcontroller or PLC. Each step of the control unit in the first horizontal module, second horizontal module, and vertical module is designed as an independent program block. Each operation process can consist of several program blocks, the order of which can be edited. The time, speed, and frequency of each step are adjustable, and the blocks are then stored in a computer with different numbers for easy recall during production operations. Attached Figure Description

[0026] Figure 1 This is a three-dimensional schematic diagram of the present invention;

[0027] Figure 2 This is a schematic diagram of the connection status of the ultrasonic cleaning tank of this utility model;

[0028] Figure 3 This is a schematic diagram of the internal structure of this utility model;

[0029] Figure 4 This is a utility model Figure 3 Enlarged view of a portion;

[0030] Figure 5 This is a rear view schematic diagram of the present invention;

[0031] Figure 6 This is a schematic diagram of the vertical module of this utility model;

[0032] Figure 7 This is a plan view of the second horizontal module of this utility model. Detailed Implementation

[0033] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present utility model without creative effort are within the protection scope of the present utility model.

[0034] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection or an indirect connection through an intermediate medium. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0035] In the description of this utility model, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0036] like Figure 1-6 As shown, an inspection device includes a main frame 1, which adopts a gantry-type upper / lower split structure. The main frame 1 has a box structure. A fixed isolation platform 2 is provided in the middle of the main frame 1. A first horizontal module 5 and a vertical module 6 connected to the first horizontal module 5 are provided in the upper space 3 of the main frame 1.

[0037] The first horizontal module 5 can move horizontally along the main frame 1, and the vertical module 6 can move vertically along the main frame 1.

[0038] Two through-holes 7 are fixedly opened on the fixed isolation platform 2, and two hollow beaker baskets 8 for placing beakers are fixedly installed in the through-holes 7.

[0039] The main frame 1 is made of stainless steel and aluminum alloy, with dimensions of 2000mm in length, 900mm in width, and 1800mm in height.

[0040] The lower space 4 of the main frame 1 is located below the fixed isolation platform 2 and a second horizontal module 9 is provided thereon. The second horizontal module 9 is provided with a separator 10 and an ultrasonic cleaning tank 11.

[0041] The main frame 1 is equipped with ultraviolet light (not shown in the figure). When the equipment is working, the ultraviolet light disinfects. When the first double door 12 and the second double door 13 are opened, the ultraviolet light is turned off.

[0042] To facilitate opening the main frame 1 for internal operations during use, the first double door 12 and the second double door 13 are provided. The upper front and rear ends of the main frame 1 are connected to the first double door 12 by hinges, and the lower front and rear ends of the main frame 1 are connected to the second double door 13 by hinges. The second double door 13 is a folding door, which is symmetrically arranged, and each folding door includes two door leaves that are hinged to each other. The relative positions of the second double door 13 are slidably connected to the upper and lower edges of the lower part of the main frame 1.

[0043] In order to facilitate rapid lateral movement by setting the first lateral module 5 during use, the first lateral module 5 includes a first drive motor 51 and a lead screw shaft 52 connected to the first drive motor 51. One end of the lead screw shaft 52 is connected to a bearing seat on the inner wall of the main frame 1.

[0044] The first transverse module 5 also includes a linear guide slider 53 connected to the lead screw shaft 52, and a connecting back plate 54 is fixedly provided on the linear guide slider 53.

[0045] To facilitate vertical movement via the longitudinal module 6 during use, the longitudinal module 6 is fixedly installed on the connecting back plate 54, and the longitudinal module 6 includes at least 3 sets.

[0046] Each set of longitudinal modules 6 includes a fixed frame 61 and a second drive motor 63 mounted on the fixed frame 61. The second drive motor 63 is connected to a longitudinal lead screw shaft 64, and the other end of the longitudinal lead screw shaft 64 is connected to a bearing seat on the fixed frame 61.

[0047] In order to operate the system by moving the suction pipe 65, the addition pipe 66, and the stirrer 67 in accordance with the vertical module 6 during use, the vertical lead screw shaft 64 is connected to an L-shaped linear guide slider 62. Each set of the vertical module 6 is equipped with a suction pipe 65, an addition pipe 66, a stirrer 67, and an ultrasonic reaction rod on the linear guide slider 62.

[0048] Each set of longitudinal modules 6 consists of, from left to right, a suction tube 65, a liquid addition tube 66, a stirrer 67, and an ultrasonic reaction rod, with two liquid addition tubes 66 provided.

[0049] The linear guide slider 62 is provided with a suction pipe 65, a liquid addition pipe 66, a stirrer 67, and an ultrasonic reaction rod arranged at intervals.

[0050] In order to facilitate the lateral movement of the separator 10 and the ultrasonic cleaning tank 11 in use, the second lateral module 9 includes a third drive motor 91 and a second lateral lead screw shaft 92 connected to the third drive motor 91. The other end of the second lateral lead screw shaft 92 is connected to a bearing seat on the main frame 1.

[0051] The second transverse module 9 also includes two sets of symmetrical support frames 93, which are bolted to the bottom of the main frame 1;

[0052] The support frame 93 is provided with a slide rail, which cooperates with the slider 95 provided on the positioning plate 94. The second transverse module 9 is connected to the nut block 96, which is fixedly connected to the positioning plate 94.

[0053] In order to facilitate the height adjustment of the separator 10 and the ultrasonic cleaning tank 11 by setting a lifting device during use, a lifting device is fixedly installed on the positioning plate 94, and the separator 10 and the ultrasonic cleaning tank 11 are installed on the lifting device.

[0054] The lifting device is either a hydraulic lifting device or an electric cylinder lifting device.

[0055] The fixed isolation platform 2 is also provided with a pipette port, which is connected to an external receiving container through a pipe.

[0056] To facilitate the control of the movement of the first horizontal module 5, the second horizontal module 9, and the vertical module 6 via a controller on a display control screen during use, a display control screen is also provided on the main frame 1. The display control screen is electrically connected to a controller, which is a microcontroller or PLC, and the controller is electrically connected to the first horizontal module 5, the second horizontal module 9, and the vertical module 6.

[0057] The main frame is equipped with casters at the bottom, allowing it to be moved as needed during use.

[0058] In use, the magnetic bead solution to be reacted is manually placed into the beaker, and two 5L beakers (outer diameter: 191mm, height 200mm) are placed in the beaker basket, which is made of 1mm thick 304 stainless steel and is hollow.

[0059] The fixed isolation platform 2 has two through channels 7, and two beaker positions are respectively set from left to right in the channels 7.

[0060] The equipment starts working, and the workflow is as follows:

[0061] The stirrer stirs the solution in the beaker with a stirring paddle, and then the ultrasonic reaction rod is lowered in beaker No. 1 to work. After the ultrasonic treatment is completed, it is lifted and moved to the cleaning tank for cleaning. At the same time, the separator moves to the beaker position and rises to work (reaction time 15-30 minutes). The waste liquid is moved to the beaker through the suction pipe and discharged into the waste liquid tank.

[0062] Repeat the above operation at the other beaker location. After adding liquid to one beaker with the liquid addition tube, wait for the other beaker to complete the separation process and then repeat the above operation.

[0063] The two beaker positions alternately repeat the steps of adding liquid, stirring + sonication, separation, and waste liquid suction 10 times. After all the work is completed, the beakers are manually removed to complete this inspection. The equipment is disinfected with ultraviolet light during operation, and the ultraviolet light is turned off when the door is opened.

[0064] The above operations are achieved by the cooperation of the first horizontal module 5, the second horizontal module 9, and the vertical module 6 to achieve the sequential and repeated addition of liquid, stirring + sonication, separation, and waste liquid aspiration of the two beaker positions.

[0065] It will be apparent to those skilled in the art that this invention is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this invention. Therefore, the embodiments should be considered illustrative and non-limiting in all respects, and the scope of this invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

[0066] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. An inspection device, characterized in that: Includes a main frame (1), which adopts a gantry-style upper / lower split structure. The main frame (1) has a box structure. A fixed isolation platform (2) is provided in the middle of the main frame (1). A first horizontal module (5) and a vertical module (6) connected to the first horizontal module (5) are provided in the upper space (3) of the main frame (1). The first horizontal module (5) can move horizontally along the main frame (1), and the vertical module (6) can move vertically along the main frame (1). Two through-holes (7) are fixedly opened on the fixed isolation platform (2), and two hollow beaker baskets (8) for placing beakers are fixedly installed in the through-holes (7). The lower space (4) of the main frame (1) is located below the fixed isolation platform (2) and a second horizontal module (9) is provided. The second horizontal module (9) is provided with a separator (10) and an ultrasonic cleaning tank (11).

2. The testing equipment according to claim 1, characterized in that: The upper front and rear ends of the main frame (1) are connected to the first double door (12) by hinges, and the lower front and rear ends of the main frame (1) are connected to the second double door (13) by hinges. The second double door (13) is a folding door, the folding doors are symmetrically arranged, and each folding door includes two door leaves that are hinged to each other. The relative positions of the second double door (13) are slidably connected to the upper and lower edges of the lower part of the main frame (1).

3. The testing equipment according to claim 2, characterized in that: The first transverse module (5) includes a first drive motor (51) and a lead screw shaft (52) connected to the first drive motor (51). One end of the lead screw shaft (52) is connected to a bearing seat on the inner wall of the main frame (1). The first transverse module (5) also includes a linear guide slider (53) connected to the lead screw shaft (52), and a connecting back plate (54) is fixedly provided on the linear guide slider (53).

4. The testing equipment according to claim 3, characterized in that: A longitudinal module (6) is fixedly installed on the connecting back plate (54), and the longitudinal module (6) includes at least 3 sets; Each of the longitudinal modules (6) includes a fixed frame (61) and a second drive motor (63) mounted on the fixed frame (61). The second drive motor (63) is connected to a longitudinal lead screw shaft (64), and the other end of the longitudinal lead screw shaft (64) is connected to a bearing seat on the fixed frame (61).

5. The testing equipment according to claim 4, characterized in that: The longitudinal lead screw shaft (64) is connected to an L-shaped linear guide slider. Each set of the longitudinal module (6) is provided with a suction pipe (65), a liquid addition pipe (66), and a stirrer (67) on the linear guide slider. Each set of longitudinal modules (6) consists of a suction pipe (65), a liquid addition pipe (66), and a stirrer (67) from left to right, with two liquid addition pipes (66).

6. The testing equipment according to claim 5, characterized in that: The second transverse module (9) includes a third drive motor (91) and a second transverse lead screw shaft (92) connected to the third drive motor (91). The other end of the second transverse lead screw shaft (92) is connected to a bearing seat on the main frame (1). The second transverse module (9) also includes two sets of symmetrical support frames (93), which are bolted to the bottom of the main frame (1); The support frame (93) is provided with a slide rail, which cooperates with the slider (95) provided on the positioning plate (94). The second transverse module (9) is connected to the nut block (96), and the nut block (96) is fixedly connected to the positioning plate (94).

7. The testing equipment according to claim 6, characterized in that: A lifting device is fixedly installed on the positioning plate (94), and a separator (10) and an ultrasonic cleaning tank (11) are installed on the lifting device. The lifting device is either a hydraulic lifting device or an electric cylinder lifting device.

8. The testing equipment according to claim 7, characterized in that: The main frame (1) is also provided with a display control screen, which is electrically connected to a controller in the position of a microcontroller or PLC. The controller is electrically connected to the first horizontal module (5), the second horizontal module (9) and the vertical module (6).

9. The testing equipment according to claim 8, characterized in that: The bottom of the main frame (1) is provided with casters.

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