An apparatus for large scale synthesis of magnetic beads

Abstract

The utility model discloses a kind of equipment for large-scale synthesis magnetic bead;The utility model discloses a base, high-efficiency manufacturing component being arranged on the surface of base and setting up reverse mould dismounting component in the surface of base, high-efficiency manufacturing component includes lower mould being detachably connected in the inside of base, hydraulic rod is arranged in the both ends of base, one end of hydraulic rod is provided with top plate, and upper mould is connected with the cooperation of top plate bottom, and upper mould is cooperatively connected on the surface of lower mould, reverse mould dismounting component includes opening being opened in the one end of base, and lower mould is cooperatively connected in the inside of opening, by high-efficiency manufacturing component being set on base, effectively solve the problem that traditional magnetic bead synthesis equipment manufacturing efficiency is lower, inconvenient for large-scale manufacturing, wherein by hydraulic rod driving top plate and upper mould, realize fast, accurate moulding and opening mould action, cooperate detachably connected lower mould, constitute efficient forming system, can realize the fast compression forming and demoulding of magnetic bead.

Description

Technical Field

[0001] This utility model relates to the technical field of magnetic bead manufacturing equipment, specifically to a device for large-scale synthesis of magnetic beads. Background Technology

[0002] Biomagnetic beads are tiny superparamagnetic microspheres composed of an iron oxide magnetic core and a polymer shell. They exhibit superparamagnetism and can rapidly aggregate or disperse in a magnetic field. Their surfaces are modified with active groups such as carboxyl groups, facilitating the coupling of biomolecules such as antibodies and nucleic acids, enabling efficient separation when combined with magnetic separation technology. Magnetic beads typically range in size from nanometers to micrometers, possessing both strong magnetic responsiveness and anti-settling properties, making them suitable for automated operations.

[0003] A publicly available patent (publication number CN218872179U) discloses a novel magnetic bead preparation device, characterized by comprising a container, a feeding port located at the top of the container, and a discharging port located at the bottom of the container; a magnetic bead collecting unit is installed at the discharging port, the magnetic bead collecting unit comprising a magnet assembly, a circular conveyor belt, and a motor. This invention solves the problem that existing magnetic bead preparation devices lack a unit for collecting magnetic beads, requiring other devices after the reaction is complete, and using methods such as centrifugation to separate and collect magnetic beads, which makes it difficult to separate non-magnetic impurities in the product. This invention improves the efficiency of magnetic bead manufacturing, and is energy-saving and environmentally friendly.

[0004] However, there are some problems in the use of existing synthetic magnetic bead equipment: 1. The overall manufacturing efficiency of the synthetic magnetic bead equipment on the market is low, which is not conducive to large-scale manufacturing; 2. The overall material discharge capability of the synthetic magnetic bead equipment on the market is low, which is not conducive to rapid material discharge. Utility Model Content

[0005] The purpose of this invention is to provide an apparatus for the large-scale synthesis of magnetic beads, so as to solve the problems mentioned in the background art.

[0006] To solve the above-mentioned technical problems, the present invention provides the following technical solution: an apparatus for large-scale synthesis of magnetic beads, comprising a base, a high-efficiency manufacturing component disposed on the surface of the base, and a mold disassembly component disposed on the surface of the base;

[0007] The high-efficiency manufacturing component includes a lower mold detachably connected inside the base. Hydraulic rods are provided at both ends of the base. A top plate is provided at one end of each hydraulic rod. An upper mold is connected to the bottom of the top plate. The upper mold is connected to the surface of the lower mold.

[0008] The mold disassembly assembly includes an opening at one end of the base, a lower mold is connected inside the opening, and an insert plate is provided inside the opening to close the opening.

[0009] As a further improvement of this utility model, the high-efficiency manufacturing component also includes connecting plates that are connected to both ends of the base, and connecting blocks are detachably connected to the surface of the connecting plates.

[0010] As a further improvement of this utility model: a hydraulic rod is fitted to the surface of the connecting block, and a fixing plate is fitted to the other end of the hydraulic rod.

[0011] As a further embodiment of this utility model: one end of the fixing plate is fixedly connected to a top plate, and both ends of the hydraulic rod are detachably connected to connecting blocks.

[0012] As a further improvement of this utility model, the mold disassembly assembly also includes a slot formed on the surface of the base, the interior of the slot communicating with the interior of the opening.

[0013] As a further improvement of this utility model: the opening is provided with a socket, and the socket and the slot are connected to a plug plate.

[0014] As a further improvement of this utility model: a handle is fixedly connected to one end of the insert plate, and an inner groove is provided on the surface of the lower mold.

[0015] Compared with the prior art, the beneficial effects of this utility model are:

[0016] This invention effectively solves the problems of low manufacturing efficiency and inconvenience for large-scale manufacturing in traditional magnetic bead synthesis equipment by using a high-efficiency manufacturing component set on the base. The hydraulic rod drives the top plate and upper mold to achieve fast and precise mold closing and opening actions. Combined with the detachable lower mold, it forms a high-efficiency molding system that enables rapid pressing and demolding of magnetic beads. This automated and continuous operation significantly reduces the single molding cycle and increases the output per unit time of the equipment, meeting the stringent requirements for production efficiency in large-scale synthesis of magnetic beads.

[0017] This invention overcomes the shortcomings of traditional equipment, such as low material discharge capacity and inconvenience in rapid unloading, by using a mold disassembly component mounted on the base. The opening at one end of the base mates with the lower mold, and the opening is closed or opened by a plate. After molding is completed, the lower mold and the molded magnetic beads can be easily removed through the opening, or the material can be quickly unloaded. This design greatly simplifies the mold removal and material discharge process, reduces equipment downtime, ensures the continuity and efficiency of the production process, and improves the overall material discharge efficiency and ease of operation. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the overall structure of an embodiment of the present utility model;

[0019] Figure 2 This is a schematic diagram of the upper mold structure according to an embodiment of the present utility model;

[0020] Figure 3 This is a schematic diagram of the mold disassembly assembly structure according to an embodiment of the present utility model;

[0021] Figure 4 This is a schematic diagram of the connecting block structure according to an embodiment of the present utility model.

[0022] In the diagram: 1. Base; 2. High-efficiency manufacturing component; 201. Lower mold; 202. Connecting plate; 203. Hydraulic rod; 204. Connecting block; 205. Fixing plate; 206. Top plate; 207. Upper mold; 3. Molding disassembly component; 301. Opening; 302. Slot; 303. Insert; 304. Insert plate; 305. Handle; 306. Inner groove. Detailed Implementation

[0023] To facilitate the solution of the problem, this utility model provides an apparatus for the large-scale synthesis of magnetic beads. The technical solutions of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this utility model, and not all of them. All other embodiments obtained by those skilled in the art based on the embodiments of this utility model without creative effort are within the scope of protection of this utility model.

[0024] Example 1

[0025] like Figures 1 to 4 As shown, this embodiment provides an apparatus for large-scale synthesis of magnetic beads, including a base 1, a high-efficiency manufacturing component 2 disposed on the surface of the base 1, and a mold disassembly component 3 disposed on the surface of the base 1. The high-efficiency manufacturing component 2 includes a lower mold 201 detachably connected inside the base 1. Hydraulic rods 203 are provided at both ends of the base 1. A top plate 206 is provided at one end of the hydraulic rods 203. An upper mold 207 is connected to the bottom of the top plate 206. The upper mold 207 is connected to the surface of the lower mold 201. The mold disassembly component 3 includes an opening 301 at one end of the base 1. The lower mold 201 is connected inside the opening 301. An insert plate 304 is provided inside the opening 301 to close the interior of the opening 301.

[0026] Example 2

[0027] In addition to all the technical features in Embodiment 1, this embodiment also includes: a top plate 206 is fixedly connected to one end of the fixing plate 205; connecting blocks 204 are detachably connected to both ends of the hydraulic rod 203; and the mold disassembly assembly 3 also includes a slot 302 opened on the surface of the base 1. The interior of the slot 302 communicates with the interior of the opening 301, and the hydraulic rod 203 is conveniently installed and used through the connecting blocks 204.

[0028] Furthermore, the high-efficiency manufacturing component 2 also includes connecting plates 202 that are connected to both ends of the base 1. Connecting blocks 204 are detachably connected to the surface of the connecting plates 202. Hydraulic rods 203 are connected to the surface of the connecting blocks 204. A fixing plate 205 is connected to the other end of the hydraulic rods 203. The connecting plates 202 facilitate the support of the base 1 so that the hydraulic rods 203 can work.

[0029] Furthermore, an insertion port 303 is provided inside the opening 301, and an insertion plate 304 is connected to the insertion port 303 and the slot 302. A handle 305 is fixedly connected to one end of the insertion plate 304, and an inner groove 306 is provided on the surface of the lower mold 201. The handle 305 facilitates the user to move the insertion plate 304.

[0030] Working Principle: The high-efficiency manufacturing component 2, mounted on the base 1, effectively solves the problems of low manufacturing efficiency and inconvenience for large-scale manufacturing in traditional magnetic bead synthesis equipment. The hydraulic rod 203 drives the top plate 206 and upper mold 207 to achieve rapid and precise mold closing and opening actions. Combined with the detachably connected lower mold 201, this forms a highly efficient molding system, enabling rapid pressing and demolding of magnetic beads. This automated and continuous operation significantly reduces the single molding cycle, increases the output per unit time, and meets the stringent requirements for production efficiency in large-scale magnetic bead synthesis. An opening 301 at one end of the base 1 engages with the lower mold 201, and is closed or opened by a plate 304. After molding, the plate 304 can be removed to easily remove the lower mold 201 along with the molded magnetic beads through the opening 301, or to quickly unload the material. This design greatly simplifies the mold removal and material unloading process, reduces equipment downtime, ensures the continuity and efficiency of the production process, and improves overall material unloading efficiency and operational convenience.

[0031] It will be apparent to those skilled in the art that this invention is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this invention. Therefore, the embodiments should be considered illustrative and non-limiting in all respects, and the scope of this invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

[0032] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. An apparatus for large-scale synthesis of magnetic beads, characterized in that: It includes a base (1), a high-efficiency manufacturing component (2) disposed on the surface of the base (1), and a mold removal component (3) disposed on the surface of the base (1); The high-efficiency manufacturing component (2) includes a lower mold (201) detachably connected inside the base (1). Hydraulic rods (203) are provided at both ends of the base (1). A top plate (206) is provided at one end of the hydraulic rods (203). An upper mold (207) is connected to the bottom of the top plate (206). The upper mold (207) is connected to the surface of the lower mold (201). The mold disassembly assembly (3) includes an opening (301) at one end of the base (1), a lower mold (201) is connected inside the opening (301), and an insert plate (304) is provided inside the opening (301) to close the inside of the opening (301).

2. The apparatus for large-scale synthesis of magnetic beads according to claim 1, characterized in that: The high-efficiency manufacturing component (2) also includes connecting plates (202) that are connected to both ends of the base (1), and connecting blocks (204) are detachably connected to the surface of the connecting plates (202).

3. The apparatus for large-scale synthesis of magnetic beads according to claim 2, characterized in that: A hydraulic rod (203) is fitted to the surface of the connecting block (204), and a fixing plate (205) is fitted to the other end of the hydraulic rod (203).

4. The apparatus for large-scale synthesis of magnetic beads according to claim 3, characterized in that: The top plate (206) is fixedly connected to one end of the fixed plate (205), and the connecting blocks (204) can be detachably connected to both ends of the hydraulic rod (203).

5. The apparatus for large-scale synthesis of magnetic beads according to claim 1, characterized in that: The mold removal assembly (3) also includes a slot (302) formed on the surface of the base (1), the interior of the slot (302) communicating with the interior of the opening (301).

6. The apparatus for large-scale synthesis of magnetic beads according to claim 5, characterized in that: The opening (301) has a socket (303) inside, and the socket (303) and the slot (302) are connected to a plug plate (304).

7. The apparatus for large-scale synthesis of magnetic beads according to claim 6, characterized in that: A handle (305) is fixedly connected to one end of the insert plate (304), and an inner groove (306) is provided on the surface of the lower mold (201).

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