A stem cell preparation storage device
Patent Information
- Application Number
- CN202522325200.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-11-03
- Publication Date
- 2026-09-04
- Estimated Expiration
- 2035-11-03
AI Technical Summary
[0003]本实用新型的目的在于提供一种干细胞制剂存储装置,旨在解决现有技术中提出现有的超低温冰箱在对干细胞制剂进行存储时大多利用抽屉式设计对多种制剂进行分类存放,但由于超低温环境下,抽屉底部与限位轨道接触部位易因微量水汽凝结结冰,导致抽拉阻力骤增,甚至出现卡滞,强行拉动可能造成抽屉变形,还可能震落内部的干细胞制剂容器
Smart Images

Figure CN224715448U_ABST
Abstract
Description
Technical Field
[0001] This utility model belongs to the field of stem cell preparation storage technology, and specifically relates to a stem cell preparation storage device. Background Technology
[0002] Stem cell preparations refer to biological products containing stem cells and their derivatives, prepared through in vitro culture and induction techniques. They possess potential medical value in repairing tissues and regenerating organs, and are widely used in cell therapy, regenerative medicine, and other fields. Because stem cells are extremely sensitive to environmental factors such as temperature and pollution, specialized storage devices are required to maintain their activity and function. Currently, there are three main types of storage devices for stem cell preparations: ultra-low temperature freezers are used for short-term or medium-term storage, using compressors to maintain an environment of -60℃ to -80℃; liquid nitrogen storage tanks use liquid nitrogen at -196℃ for long-term preservation, almost completely stopping cell metabolism; and programmed cooling devices are used as pretreatment equipment, reducing cell cryopreservation damage through step-cooling. The core of the ultra-low temperature freezer is a cascade refrigeration system: two compressors connected in series respectively complete the "high-temperature section" (exhausting heat from -20℃ to room temperature) and the "low-temperature section" (lowering the temperature from -20℃ to -80℃), while an insulation layer reduces cold loss. Simultaneously, internal air circulation ensures even distribution of cold air throughout the storage area, and a precise temperature control system maintains stable temperatures, providing a safe short- to medium-term storage environment for stem cell preparations. Existing ultra-low temperature freezers mostly utilize a drawer-type design for storing stem cell preparations, allowing for the categorization and storage of various preparations. However, due to the ultra-low temperature environment, the contact area between the bottom of the drawer and the limiting track is prone to condensation and ice formation due to trace amounts of moisture, leading to a sudden increase in resistance when pulling out the drawer, and even jamming. Forcibly pulling it out may cause the drawer to deform and may also shake off the stem cell preparation containers inside. Secondly, friction-type sliding systems have poor stability, and the drawer is prone to shaking when pulled out. For stem cell preparations containing fragile cryovials or cryopreservation bags, the bumps may cause the containers to collide and break, leading to sample contamination or loss. Utility Model Content
[0003] The purpose of this invention is to provide a stem cell preparation storage device, aiming to solve the problem that existing ultra-low temperature freezers mostly use a drawer-type design to classify and store various preparations when storing stem cell preparations. However, due to the ultra-low temperature environment, the contact area between the bottom of the drawer and the limiting track is prone to condensation and ice formation due to trace amounts of water vapor, resulting in a sudden increase in the resistance to pulling out the drawer, or even jamming. Forcibly pulling out the drawer may cause it to deform and may also shake off the stem cell preparation containers inside. Secondly, the stability of friction sliding is poor, and the drawer is prone to shaking when pulled out. For stem cell preparations containing fragile cryovials or cryopreservation bags, the bumps may cause the containers to collide and break, leading to sample contamination or loss.
[0004] To achieve the above objectives, this utility model provides the following technical solution: a stem cell preparation storage device, comprising a low-temperature refrigerator body, a partition plate installed on the inner wall surface of the low-temperature refrigerator body, a slide rod installed on the top surface of the partition plate, a ball bearing slider slidably connected to the surface of the slide rod, a tray connected to the top surface of the ball bearing slider, a slot formed on the top surface of the tray, a rubber rod inserted into the slot, the top surface of the rubber rod adhered to the bottom of the partition frame, a protective cover connected to the front surface of the partition frame, an insert plate sleeved on one side surface of the opening end of the protective cover, a limiting groove formed on the top surface of the insert plate, a clamping plate inserted into the limiting groove, and a crossbar on the surface of the clamping plate inserted into a circular groove on the surface of a label plate.
[0005] As a preferred embodiment of the stem cell preparation storage device of this utility model, the two ball bearing sliders are symmetrically distributed on the bottom surface of the tray away from the handle end, and the shape and size of the ball bearing sliders are adapted to the top groove of the partition plate.
[0006] As a preferred embodiment of the stem cell preparation storage device of this utility model, four sets of slots are equally spaced on the surface of the tray, and the shape and size of the slots are adapted to the rubber rod.
[0007] As a preferred embodiment of the stem cell preparation storage device of this utility model, the separator is a rectangular box-shaped structure, the shape and size of which are adapted to the rectangular groove on the top of the tray.
[0008] As a preferred embodiment of the stem cell preparation storage device of this utility model, the protective cover has a rectangular groove on its surface, the shape and size of which are adapted to the rectangular block on the surface of the insert plate.
[0009] As a preferred embodiment of the stem cell preparation storage device of this utility model, the clamp is an L-shaped integrated structure with a set of cylindrical crossbars arranged longitudinally on its surface. The shape and size of the crossbars are adapted to the through groove on the surface of the label plate. The two clamps and the label plate intersect to form a T-shaped structure, the shape and size of which are adapted to the limiting groove.
[0010] Compared with the prior art, the beneficial effects of this utility model are: By using a ball bearing slider installed at the bottom of the tray to slide on the slide bar, even if the slide bar is slightly frosted or icy in an ultra-low temperature environment, the rolling friction can reduce the risk of jamming and prevent the tray from deforming or the internal stem cell preparation containers from shaking due to forced pulling. In addition, the rolling friction distributes the force more evenly, making it less likely to wobble or jam, and can reduce the impact on the internal cryopreservation tubes and cryopreservation bags, thereby improving the smoothness and stability of the tray pulling in an ultra-low temperature environment. In addition, the silicone protective cover installed on the separator rack can easily fix the label plate indicating the type of stem cell preparation to the surface of the separator rack. This makes it easy to quickly identify the stem cell preparation to be taken after the surface of the separator rack is covered with frost in ultra-low temperature environments, thereby improving the efficiency of taking stem cell preparations and reducing operation time and the risk of temperature fluctuations. Attached Figure Description
[0011] The accompanying drawings are provided to further illustrate the present invention and form part of the specification. They are used together with the embodiments of the present invention to explain the present invention, but do not constitute a limitation thereof. In the drawings: Figure 1 This is a schematic diagram of the main structure of this utility model; Figure 2 This is a schematic diagram of the main cross-sectional structure of this utility model; Figure 3 This is an exploded structural diagram of the tray and divider components of this utility model; Figure 4 This is an exploded structural diagram of the insert plate and clamping plate of this utility model; Figure 5 This is a schematic diagram of the connection structure between the separator and the protective cover of this utility model.
[0012] In the diagram: 1. Low-temperature refrigerator body; 2. Divider plate; 3. Slide rod; 4. Ball bearing slider; 5. Tray; 6. Slot; 7. Rubber rod; 8. Divider frame; 9. Protective cover; 10. Insert plate; 11. Limiting groove; 12. Clamping plate; 13. Label plate. Detailed Implementation
[0013] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0014] Please see Figures 1-5This utility model provides the following technical solution: a stem cell preparation storage device, including a low-temperature refrigerator body 1, a partition plate 2 installed on the inner wall surface of the low-temperature refrigerator body 1, a slide rod 3 installed on the top surface of the partition plate 2, a ball bearing slider 4 slidably connected to the surface of the slide rod 3, a tray 5 connected to the top surface of the ball bearing slider 4, a slot 6 opened on the top surface of the tray 5, a rubber rod 7 inserted into the surface of the slot 6, the top surface of the rubber rod 7 being adhered to the bottom of the partition frame 8, a protective cover 9 connected to the front surface of the partition frame 8, an insert plate 10 sleeved on one side surface of the opening end of the protective cover 9, a limiting groove 11 opened on the top surface of the insert plate 10, a clamping plate 12 inserted into the surface of the limiting groove 11, and a crossbar on the surface of the clamping plate 12 being inserted into a circular groove on the surface of the label plate 13. In this design, the low-temperature refrigerator body 1 and the partition plate 2 constitute the body of an ultra-low temperature refrigerator, and a large number of related components are set in the body of the ultra-low temperature refrigerator. Since these are existing technologies and the core content of this technical solution is irrelevant to them, they will not be described in detail in this technical solution. The main model of the ultra-low temperature freezer in this solution is: SUFsg7001.
[0015] In use: The low-temperature refrigerator achieves stable storage of stem cell preparations through a two-stage refrigeration system: two compressors respectively handle the refrigeration tasks in the high-temperature range (-20℃ to room temperature) and the low-temperature range (-20℃ to -86℃), using environmentally friendly refrigerants R290 and R170 to quickly lower the chamber temperature to -86℃ in direct cooling mode. Its intelligent temperature control system monitors in real time through calibrated temperature sensors, combined with air circulation technology to ensure that the temperature uniformity error inside the chamber is less than ±1℃, and supports dual temperature monitoring (built-in and external sensors), effectively avoiding the impact of temperature fluctuations on stem cell activity.
[0016] Preferably, two ball bearing sliders 4 are symmetrically distributed on the bottom surface of the tray 5 away from the handle end, and the shape and size of the ball bearing sliders 4 are adapted to the top groove of the partition plate 2.
[0017] In practical use, when it is necessary to take the stem cell preparation container placed on the tray 5, the handle on the surface of the tray 5 can be pulled away from the side of the low temperature refrigerator body 1, so that the ball bearing slider 4 at the bottom of the tray 5 can slide on the slide bar 3, thus smoothly pulling the tray 5 in the low temperature environment. At the same time, the surface of the slide bar 3 can be sprayed with molybdenum disulfide low temperature lubricant.
[0018] Preferably, four sets of slots 6 are equally spaced on the surface of the tray 5, and the shape and size of the slots 6 are adapted to the rubber rod 7.
[0019] In actual use, insert the rubber rod 7 at the bottom of the divider 8 into the slot 6 to fix its position in the rectangular groove at the top of the tray 5.
[0020] Preferably, the divider 8 is a rectangular box-shaped structure, and its shape and size are adapted to the rectangular groove on the top of the tray 5.
[0021] In practical use, the stem cell preparations to be stored are inserted into the circular grooves opened on the inner wall of the separator 8 in sequence. The support plate structure in the middle section of its inner wall supports and limits the inserted stem cell preparation containers to prevent them from shaking when moving.
[0022] Preferably, a rectangular groove is formed on the surface of the protective cover 9, the shape and size of which are adapted to the rectangular block on the surface of the insert plate 10.
[0023] In practical use, the insert plate 10 inserted into the protective cover 9 can be pulled out, the preparation type can be marked on the surface of the clamp plate 12, and the connection between the silicone protective cover 9 and the insert plate 10 can be fixed by inserting them together.
[0024] Preferably, the clamping plate 12 is an L-shaped integrated structure with a set of cylindrical crossbars arranged longitudinally on its surface. The shape and size of the crossbars are adapted to the through groove on the surface of the label plate 13. The two clamping plates 12 and the label plate 13 intersect to form a T-shaped structure, the shape and size of which are adapted to the limiting groove 11.
[0025] In practical use, the preparation type is marked on the surface of the clamp 12, and then the two clamps 12 are respectively inserted into the circular grooves on the surface of the clamp 12 to fix the connection between the two. Then, the clamps 12 and the clamp 12 are inserted into the limiting groove 11 to fix their position inside the protective cover 9.
[0026] Working principle: When storing stem cell preparations for short to medium term, select a divider 8 with a corresponding groove size according to the size of the stem cell preparation container to be stored. Then, insert the stem cell preparations to be stored into the circular grooves on the inner wall of the divider 8 in sequence. The support plate structure in the middle of the inner wall supports and limits the inserted stem cell preparation containers to prevent them from shaking when moving. Then, insert the rubber rod 7 at the bottom of the divider 8 into the slot 6 to fix its position in the rectangular groove at the top of the tray 5. When storing a large number of stem cell preparations, repeat the above operation and place the stem cell preparations to be stored on the three sets of trays 5 respectively. After placing the preparations in the divider 8, the insert plate 10 inserted into the protective cover 9 can be pulled out, and the preparation type can be marked on the surface of the clamp plate 12. Then, the two clamp plates 12 are inserted into the circular grooves on the surface of the clamp plate 12 to fix the connection between the two. Then, the clamp plate 12 and the clamp plate 12 are inserted into the limiting groove 11 to fix their position in the protective cover 9. Then, the protective cover 9 and the insert plate 10 made of transparent silicone material are used to mark the type of stem cell preparations in each divider 8 in the ultra-low temperature environment by the low temperature resistance and anti-frost properties of silicone material, so that the required stem cell preparations can be quickly and accurately retrieved in the future.
[0027] Finally, it should be noted that the above are merely preferred embodiments of this utility model and are not intended to limit the utility model. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.
Claims
1. A stem cell preparation storage device, comprising a low-temperature refrigerator body (1), characterized in that: The inner wall surface of the low-temperature refrigerator body (1) is equipped with a partition plate (2), the top surface of the partition plate (2) is equipped with a slide rod (3), the surface of the slide rod (3) is slidably connected to a ball bearing slider (4), the top surface of the ball bearing slider (4) is connected to a tray (5), the top surface of the tray (5) is opened with a slot (6), the surface of the slot (6) is inserted with a rubber rod (7), the top surface of the rubber rod (7) is bonded to the bottom of the partition frame (8), the front end surface of the partition frame (8) is connected to a protective cover (9), one side surface of the opening end of the protective cover (9) is fitted with an insert plate (10), the top surface of the insert plate (10) is opened with a limiting groove (11), the surface of the limiting groove (11) is inserted with a clamping plate (12), the crossbar on the surface of the clamping plate (12) is inserted into the circular groove on the surface of the label plate (13).
2. The stem cell preparation storage device according to claim 1, characterized in that: Two ball bearing sliders (4) are symmetrically distributed on the bottom surface of the tray (5) away from the handle end. The shape and size of the ball bearing sliders (4) are adapted to the top groove of the partition plate (2).
3. The stem cell preparation storage device according to claim 2, characterized in that: The tray (5) has four slots (6) evenly spaced on its surface, and the shape and size of the slots (6) are adapted to the rubber rod (7).
4. The stem cell preparation storage device according to claim 3, characterized in that: The divider (8) is a rectangular box structure, and its shape and size are adapted to the rectangular groove on the top of the tray (5).
5. A stem cell preparation storage device according to claim 1, characterized in that: The protective cover (9) has a rectangular groove on its surface, the shape and size of which are adapted to the rectangular block on the surface of the insert plate (10).
6. The stem cell preparation storage device according to claim 1, characterized in that: The clamp (12) is an "L" shaped integrated structure with a set of cylindrical crossbars arranged longitudinally on its surface. The shape and size of the crossbars are adapted to the through groove on the surface of the label plate (13). The two clamps (12) and the label plate (13) intersect to form a "T" shaped structure, the shape and size of which are adapted to the limiting groove (11).