Storage box for cell transport

Abstract

The application discloses a storage box for cell transportation and relates to the technical field of cell storage. The application comprises a box body, a cover body, a flexible block, a positioning mechanism and a cooling mechanism. The box body is detachably connected with the cover body. The flexible block is connected with the bottom side of the cover body. A plurality of accommodating grooves are annularly arranged on the outer side of the flexible block and linearly arranged along the length direction of the flexible block. The positioning mechanism is arranged in each accommodating groove. The test tube inserted into the accommodating groove is fixed through the positioning mechanism. The cooling mechanism is arranged in the box body. The temperature in the box body can be reduced through the cooling mechanism. The test tube is inserted into the accommodating groove on the circumferential side of the flexible block and fixed through the positioning mechanism, so that the technical effect of supporting and damping the test tube is achieved. Compared with the prior art, the application has the advantages of simple structure, convenient assembly and low failure rate.

Description

Technical Field

[0001] This application relates to the field of cell storage technology, specifically a storage box for cell transport. Background Technology

[0002] Cells are extremely fragile and precious biological samples, and the transportation environment (whether by air or land) is full of variables, including physical vibration, impact, and even container overturning. In order to ensure that the precious cell samples in the storage container maintain a high survival rate, good activity and functional integrity after arriving at their destination, it is necessary to protect them with professional storage boxes.

[0003] Utility model patent CN217049641U3 discloses a stem cell storage and transportation box that is easy to access. It includes a main body, a refrigeration chamber, and a drawer. The main body has an installation opening on its upper side, inside which a material access component is installed. This component includes an embedded box, a support frame on its lower side, a clamping block on the upper inner side of the support frame, a first spring on the outer side of the clamping block, a limiting seat on the lower inner side of the support frame, and a second spring on the lower side of the limiting seat. An air intake mesh is located on the front of the drawer. This novel design supports test tubes via the clamping block and limiting seat, allowing the test tubes to be supported and damped independently. The material access component can be easily removed through the installation opening, ice packs can be stored in the drawer, and cold air circulates through a fan, resulting in uniform temperature within the box.

[0004] However, the above technical solutions have the following drawbacks: 1. Numerous components: Fixing a single test tube requires multiple parts, including two clamps, two first springs, one limiting seat, and at least one second spring. If a support frame needs to hold 10 test tubes, the number of parts increases dramatically, leading to high production costs. 2. Cumbersome assembly process: During production and assembly, a large number of springs and small parts need to be precisely installed into each test tube position, which is more time-consuming and labor-intensive than simple slotting or using uniform elastic pads. 3. Increased potential failure points: Springs may be at risk of fatigue failure after long-term use, and the more small parts there are, the greater the potential risk of loosening and damage. Therefore, it is necessary to propose a storage box for cell transport. Utility Model Content

[0005] The technical problem to be solved by this utility model is the technical problem mentioned in the background art of existing stem cell storage and transportation boxes, which have a large number of components, complicated assembly process and many potential failure points.

[0006] To achieve the above objectives, this application provides the following technical solution: A cell transport storage box includes a box body, a lid, a flexible block, a positioning mechanism, and a cooling mechanism. The box body and the lid are detachably connected. The flexible block is connected to the bottom side of the lid. Multiple receiving slots are distributed in a ring around the outer side of the flexible block, and the multiple receiving slots are linearly distributed along the length of the flexible block. Each receiving slot is provided with a positioning mechanism, which fixes the test tube inserted into the receiving slot. A cooling mechanism is provided inside the box to reduce the temperature inside the box.

[0007] Preferably, the receiving groove is inclined, and the end of the receiving groove at the higher position is located outside the flexible block.

[0008] In the above scheme, the positioning mechanism includes a conical sleeve, which is coaxially disposed in the receiving groove. A cylindrical groove is provided in the receiving groove, and the conical sleeve is connected to the cylindrical groove.

[0009] In the above scheme, the cooling mechanism includes a heat-conducting box and heat-conducting plates. The heat-conducting box is installed on the bottom surface of the box body, the heat-conducting plates are distributed in a ring on the top of the heat-conducting box, and the heat-conducting box is filled with a cooling medium.

[0010] Preferably, the bottom of the flexible block abuts and overlaps with the top of the heat-conducting box.

[0011] Preferably, the flexible block has a communicating cavity, the receiving groove is connected to the communicating cavity, and the flexible block is provided with a cooling component, which can reduce the air temperature inside the communicating cavity.

[0012] In the above scheme, the cooling component includes a heat-conducting rod and heat-conducting fins. The heat-conducting rod is coaxially disposed in the communicating cavity, and the heat-conducting fins are distributed in a ring around the heat-conducting rod. A sealing plate is connected to the bottom of the flexible block, and an opening is opened at the top of the heat-conducting box. The sealing plate is placed on the opening, and the bottom end of the heat-conducting rod passes through the flexible block and the sealing plate from top to bottom and is inserted into the opening. A pressure relief valve is installed on the cover.

[0013] Preferably, the box body and the lid body are hexagonal in design.

[0014] Preferably, the bottom of the cover has a plurality of guide rods arranged in a ring, and the box body has a plurality of slots that fit together, with the plurality of guide rods slidingly inserted into the plurality of slots respectively.

[0015] Preferably, an annular plate is adhered to the top of the flexible block, and the annular plate is rotatably mounted on the bottom side of the cover.

[0016] Compared with the prior art, the beneficial effects of this application are as follows: This application adopts the technique of inserting the test tube into the receiving groove on the periphery of the flexible block and fixing it by the positioning mechanism to achieve the technical effect of supporting and damping the test tube. Compared with the prior art, this application has the advantages of simple structure, easy assembly and less prone to failure. Attached Figure Description

[0017] Figure 1 This is a three-dimensional structural diagram of the present application; Figure 2 For this application Figure 1 Structural sectional view; Figure 3 This is a schematic diagram of the structure of the cover of this application; Figure 4 For this application Figure 3 Structural sectional view; Figure 5 For this application Figure 4 Enlarged view of point A; Figure 6 This is a schematic diagram of the structure of the box body in this application; Figure 7 For this application Figure 6 A structural sectional view.

[0018] In the diagram: 1. Box body; 11. Slot; 2. Cover; 21. Guide rod; 3. Flexible block; 31. Receiving groove; 32. Connecting cavity; 4. Positioning mechanism; 41. Conical sleeve; 42. Cylindrical groove; 5. Cooling mechanism; 51. Heat-conducting box; 511. Opening; 52. Heat-conducting plate; 6. Cooling component; 61. Heat-conducting rod; 62. Heat-conducting fin; 7. Sealing plate; 8. Pressure relief valve; 9. Annular plate; 10. Lock. Detailed Implementation

[0019] The technical solutions in the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings, and the structural features will be further detailed in conjunction with the working state. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of the embodiments. Based on the embodiments in this application, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of this application.

[0020] Please see Figures 1 to 7 This application provides a storage box for cell transport, the technical solution of which is as follows: A cell transport storage box, as shown in the reference Figure 1 , Figure 3 , Figure 4 , Figure 5 , Figure 6 and Figure 7The system includes a box body 1, a cover body 2, a flexible block 3, a receiving groove 31, a positioning mechanism 4, and a cooling mechanism 5. After the staff inserts multiple test tubes containing cells into the receiving groove 31 around the flexible block 3, the positioning mechanism 4 can fix the test tubes so that they are not easily detached from the flexible block 3. Then, the cover body 2 can be connected to the box body 1. The internal space of the box body 1 can contain and protect the flexible block 3 and the exposed ends of the test tubes. The cooling mechanism 5 can reduce the internal temperature of the box body 1, thereby allowing the cells stored in the test tubes to be preserved at low temperature and making them less susceptible to damage.

[0021] The box body 1 and the cover body 2 are detachably connected. The cover body 2 and the box body 1 are detachable through the latch 10. The cover body 2 and the box body 1 are made of multiple layers of heat insulation materials such as aluminum foil and fiberglass paper. The inner side of the cover body 2 and the box body 1 are both coated with aluminum metal, which can reflect most of the radiant heat, thus playing a role in heat preservation.

[0022] The flexible block 3 is specifically a silicone block. The flexible block 3 is adhered to the bottom side of the cover 2. The outer side of the flexible block 3 has a ring of receiving grooves 31, and multiple receiving grooves 31 are linearly distributed along the length of the flexible block 3. Each receiving groove 31 is provided with a positioning mechanism 4. The positioning mechanism 4 can fix the test tube inserted into the receiving groove 31. At the same time, when the test tube is inserted into the receiving groove 31, the flexible block 3 will generate a certain amount of frictional force on the surface of the test tube, so that the test tube will not easily fall out of the receiving groove 31. Together with the positioning mechanism 4, it can achieve a double fixing effect.

[0023] After the cover 2 is connected to the box 1, as follows Figure 2 As shown, the flexible block 3 is vertically inserted into the box 1. At this time, there is a gap between the exposed end of the test tube on its periphery and the bottom side of the cover 2 and the inner wall of the box 1, which avoids direct contact and further reduces impact and temperature fluctuation.

[0024] The box 1 is equipped with a cooling mechanism 5, which can reduce the temperature inside the box 1 to preserve the cells stored in the test tube at low temperature and prevent them from being damaged.

[0025] This application employs a method of inserting test tubes into the receiving grooves 31 on the periphery of the flexible block 3 and fixing them with the positioning mechanism 4 to achieve the technical effect of supporting and damping the test tubes. Compared with the prior art, this application has the advantages of simple structure, easy assembly and low failure rate.

[0026] As one embodiment of this application, refer to Figure 2 The receiving groove 31 is inclined, with the higher end of the receiving groove 31 located outside the flexible block 3. The angle between the length direction of the receiving groove 31 and the axis of the flexible block 3 is acute. This design, such as... Figure 2As shown, when the box 1 falls over during transportation, the sliding direction of the test tube from the receiving groove 31 has an angle with the vertical downward gravity. That is, the test tube no longer needs to overcome the simple vertical downward gravity, but a component of gravity along the inclined receiving groove 31. This component is much smaller than the total weight of the test tube itself, making it more difficult for the test tube to slide out of the inclined receiving groove 31.

[0027] As one embodiment of this application, refer to Figure 4 , Figure 5 The positioning mechanism 4 includes a conical sleeve 41, which is coaxially disposed in the receiving groove 31. The minimum inner diameter of the conical sleeve 41 is slightly smaller than the outer diameter of the test tube and is used to position the insertion end of the test tube. A cylindrical groove 42 is provided in the receiving groove 31. The conical sleeve 41 is connected to the cylindrical groove 42. The conical sleeve 41 and the flexible block 3 are integrally constructed.

[0028] When the test tube is fully inserted, its rounded end will enter the cylindrical groove 42 through the receiving groove 31. At this time, the rounded end of the test tube will first be inserted into the end of the conical sleeve 41 for transition, so that the test tube can enter the conical sleeve 41.

[0029] It should be specifically explained here that the positioning of the test tube is achieved through the elastic interference fit between the conical sleeve 41 and the test tube body. After the round end of the test tube passes through the conical sleeve 41, its cylindrical body part is in continuous contact with the inner wall of the conical sleeve 41. Since the minimum inner diameter of the conical sleeve 41 is slightly smaller than the outer diameter of the test tube, the conical sleeve 41, made of flexible material, will undergo slight elastic deformation, thereby applying a uniform, radially inward clamping force to the test tube body. This continuous clamping force generates a huge static friction force, which effectively prevents the test tube from backing up or loosening due to vibration during transportation, thus achieving reliable positioning.

[0030] As one embodiment of this application, refer to Figure 7 The cooling mechanism 5 is used to cool the inside of the box 1. It includes a heat-conducting box 51 and heat-conducting plates 52. The heat-conducting box 51 is installed on the bottom surface of the box 1. The heat-conducting plates 52 are distributed in a ring on the top of the heat-conducting box 51. The heat-conducting plates 52 are constructed on the heat-conducting box 51, which can increase the contact area between the heat-conducting box 51 and the air inside the box 1, so as to reduce the internal temperature of the box 1. The heat-conducting box 51 is filled with a cooling medium. According to the temperature requirements of the cells in the test tube, the cooling medium can be dry ice, liquid nitrogen, etc., which can provide a continuous and strong cold source for the heat-conducting box 51.

[0031] As one embodiment of this application, refer to Figure 2The bottom of the flexible block 3 is in contact with the top of the heat-conducting box 51. During transportation, the vehicle starts and stops and the road bumps will generate huge inertial forces and impact forces. The flexible block 3 itself and the test tubes inserted into it constitute an upper mass block. Without bottom support, it is only connected by the cover 2. Under vibration, it is very easy to shake, swing or even twist. By making the bottom of the flexible block 3 contact with the heat-conducting box 51, the shaking tendency of the flexible block 3 can be suppressed, thereby improving the structural stability of the flexible block 3.

[0032] As one embodiment of this application, refer to Figure 2 and Figure 4 The flexible block 3 has a connecting cavity 32 inside, and the receiving groove 31 is connected to the connecting cavity 32. The flexible block 3 is equipped with a cooling element 6, which can reduce the air temperature inside the connecting cavity 32. According to the scientific phenomenon that air expands when heated and contracts when cooled, the temperature drop will directly lead to a decrease in air pressure inside the connecting cavity 32, thereby forming a negative pressure environment. The generated negative pressure will act evenly and synchronously on each test tube. By using negative pressure suction to fix all the test tubes in the box, the fixation effect of the test tubes can be further improved.

[0033] It should be specifically noted that the end of the conical sleeve 41 with a smaller inner diameter is close to the opening of the receiving groove 31. Under the action of negative pressure, the conical sleeve 41 will be forced to undergo more significant elastic deformation and increase its radial clamping force on the test tube, ensuring that the test tube and the conical sleeve 41 are always in the best fit, and further improving the fixing effect of the conical sleeve 41.

[0034] As one embodiment of this application, refer to Figure 1 , Figure 2 and Figure 4The cooling component 6 is specifically designed for efficient cooling of the connecting cavity 32. It includes a heat-conducting rod 61 and heat-conducting fins 62. The heat-conducting rod 61 is coaxially disposed within the connecting cavity 32, and the heat-conducting fins 62 are distributed in a ring around the heat-conducting rod 61. The heat-conducting fins 62 increase the heat exchange surface area between the heat-conducting rod 61 and the air in the connecting cavity 32. A sealing plate 7 is connected to the bottom of the flexible block 3. The sealing plate 7 is made of PTFE material. An opening 511 is opened at the top of the heat-conducting box 51. The sealing plate 7 overlaps with the opening 511. The sealing plate 7 not only seals the opening 511 to prevent cooling media such as dry ice and liquid nitrogen from flowing out of the opening 511, but also acts as a thermal barrier. To prevent the lower, overcooled surface from causing low-temperature damage to the flexible block 3, the bottom end of the heat-conducting rod 61 passes through the flexible block 3 and the sealing plate 7 sequentially from top to bottom and is inserted into the opening 511. The bottom end of the heat-conducting rod 61 is in direct contact with the cooling medium, which can quickly cool the connecting cavity 32. By adopting this efficient heat conduction path of the heat-conducting rod 61, this application can preferentially cool the narrow connecting cavity 32, so that its temperature can be rapidly reduced, and its internal temperature can be kept lower than the internal space of the box 1, which has a large heat capacity and is mainly cooled slowly by air convection. That is, the pressure difference can be maintained by utilizing the difference in heat capacity between the connecting cavity 32 and the air inside the box 1, thereby generating and maintaining a fixed pressure difference.

[0035] The cover 2 is equipped with a pressure relief valve 8. The pressure relief valve 8 is designed to deal with extreme situations: when the cooling medium "liquid nitrogen" vaporizes rapidly due to insulation failure, it will cause the pressure inside the box 1 to rise abnormally. The pressure relief valve 8 can automatically open when the internal pressure exceeds the set safety threshold, and release the excessive pressure to the outside of the box in time. This effectively prevents safety accidents such as the box 1 bursting or the cover 2 being blown open due to pressure accumulation, and ensures safety during transportation.

[0036] As one embodiment of this application, refer to Figure 1 The box body 1 and the lid 2 are hexagonal in design, so that if the box body 1 is accidentally tipped over during transportation, it only needs a very small angular shift to stabilize from one side to the adjacent side. This makes the box body 1 less likely to roll over a long distance. This "easy to stabilize and difficult to roll" characteristic can effectively avoid the violent impact and centrifugal force caused by the continuous rolling of the box body 1, thereby minimizing the risk of physical damage to the test tubes inside the box body 1 and providing a higher level of protection for cell samples.

[0037] As one embodiment of this application, refer to Figure 3 and Figure 6The bottom of the cover 2 has multiple guide rods 21 arranged in a ring. The box 1 has multiple slots 11 that fit together. The guide rods 21 are slidably inserted into the slots 11. It should be noted that the storage space inside the box 1 is cylindrical. The number of slots 11 and guide rods 21 is consistent with the prism shape of the box 1 and the cover 2. The design of the guide rods 21 and slots 11 has the following advantages: 1. When connecting the cover 2 and the box 1, the ends of the guide rods 21 need to be inserted into the slots 11 first. At this time, the movement of the cover 2 can be guided so that during the process of the flexible block 3 entering the box 1, the test tubes on the periphery of the flexible block 3 will not contact the inner wall of the box 1, which can further protect the test tubes. 2. After the cover 2 is separated from the box 1, the multiple guide rods 21 can be used as supports to support the cover 2. That is, the cover 2 is placed on the table by the multiple guide rods 21. In this state, the flexible block 3 does not contact the table and is not squeezed by the weight of the cover 2, which makes it easy to insert the test tubes into the receiving groove 31.

[0038] As one embodiment of this application, refer to Figure 4 The top of the flexible block 3 is attached to an annular plate 9, which is rotatably installed on the bottom side of the cover 2. The annular plate 9 is rotatably connected to the cover 2 through a bearing. The entire flexible block 3 and all the test tubes inserted on it can rotate freely 360 degrees under the cover 2 as a whole. When the staff rotates the flexible block 3, it is convenient to insert the test tubes into the receiving groove 31 or take them out of the receiving groove 31.

[0039] Usage process: The user removes the cover 2 from the box 1 and supports the cover 2 with multiple guide rods 21. When the cover 2 is placed vertically on the workbench, the user can rotate the flexible block 3 to insert multiple test tubes into the receiving grooves 31 on the periphery of the flexible block 3. When the round end of the test tube is inserted into the cylindrical groove 42, the test tube can be fixed by the conical sleeve 41. Then, the cooling medium can be injected into the heat conduction box 51 inside the box 1 through the opening 511. Then, the cover 2 is lifted and its bottom guide rod 21 is inserted into the slot 11 of the box 1. The cover 2 is then driven to move the flexible block 3 into the box 1 until the sealing plate 7 closes the opening 511 and the bottom end of the heat conduction rod 61 is inserted into the cooling medium, thus completing the installation.

[0040] Although embodiments of this application have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of this application, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A storage box for cell transport, characterized in that, The device includes a box body (1), a cover body (2), a flexible block (3), a positioning mechanism (4), and a cooling mechanism (5). The box body (1) and the cover body (2) are detachably connected. The flexible block (3) is connected to the bottom side of the cover body (2). Multiple receiving grooves (31) are distributed in a ring on the outer side of the flexible block (3), and the multiple receiving grooves (31) are linearly distributed along the length direction of the flexible block (3). The receiving grooves (31) are all equipped with positioning mechanisms (4). The test tubes inserted into the receiving grooves (31) are fixed by the positioning mechanisms (4). The box body (1) is equipped with a cooling mechanism (5). The temperature inside the box body (1) can be reduced by the cooling mechanism (5).

2. The cell transport storage box according to claim 1, characterized in that: The receiving groove (31) is set at an angle, and the end of the receiving groove (31) at the higher position is located outside the flexible block (3).

3. A cell transport storage box according to claim 2, characterized in that: The positioning mechanism (4) includes a conical sleeve (41), which is coaxially disposed in the receiving groove (31). A cylindrical groove (42) is provided in the receiving groove (31), and the conical sleeve (41) is connected to the cylindrical groove (42).

4. A cell transport storage box according to claim 3, characterized in that: The cooling mechanism (5) includes a heat-conducting box (51) and heat-conducting plates (52). The heat-conducting box (51) is installed on the bottom surface of the box body (1), and the heat-conducting plates (52) are distributed in a ring on the top of the heat-conducting box (51). The heat-conducting box (51) is filled with a cooling medium.

5. A cell transport storage box according to claim 4, characterized in that: The bottom of the flexible block (3) is in contact with the top of the heat-conducting box (51).

6. A cell transport storage box according to claim 5, characterized in that: The flexible block (3) has a connecting cavity (32) inside, and the receiving groove (31) is connected to the connecting cavity (32). The flexible block (3) is provided with a cooling component (6), which can reduce the air temperature inside the connecting cavity (32).

7. A cell transport storage box according to claim 6, characterized in that: The cooling component (6) includes a heat-conducting rod (61) and heat-conducting fins (62). The heat-conducting rod (61) is coaxially disposed in the communicating cavity (32). The heat-conducting fins (62) are distributed in a ring around the heat-conducting rod (61). The bottom of the flexible block (3) is connected to a sealing plate (7). The top of the heat-conducting box (51) has an opening (511). The sealing plate (7) is placed on the opening (511). The bottom end of the heat-conducting rod (61) passes through the flexible block (3) and the sealing plate (7) from top to bottom and is inserted into the opening (511). A pressure relief valve (8) is installed on the cover (2).

8. A cell transport storage box according to claim 1, characterized in that: The box body (1) and the cover body (2) are hexagonal in design.

9. A cell transport storage box according to claim 8, characterized in that: The bottom of the cover (2) has a ring of multiple guide rods (21), and the box (1) has multiple slots (11) that are opened in cooperation. The multiple guide rods (21) are slidably inserted into the multiple slots (11).

10. A cell transport storage box according to claim 9, characterized in that: The top of the flexible block (3) is attached to an annular plate (9), which is rotatably mounted on the bottom side of the cover (2).

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